## Tue Feb 11 18:15:15 2025 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/shared_data/ZYJ_Metagenome/metagenome_bucong/mmseqs/SRR17522547//SRR17522547_p_cluster_rep_seq.fasta --output SRR17522547 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/shared_data/ZYJ_Metagenome/metagenome_bucong/eggnog/SRR17522547 --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k141_11994_1 203122.Sde_0634 1.37e-20 93.6 COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,46A6E@72275|Alteromonadaceae 1236|Gammaproteobacteria V Inner membrane protein CreD creD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06143 - - - - ko00000 - - - CreD k141_11994_2 748658.KB907313_gene2107 1.84e-48 164.0 COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,1T4CS@1236|Gammaproteobacteria,1WZQU@135613|Chromatiales 135613|Chromatiales S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_4302_1 1380380.JIAX01000008_gene1831 1.72e-42 155.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria 28211|Alphaproteobacteria C FAD linked oxidase - - 1.1.3.8,1.1.98.3 ko:K00103,ko:K16653 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 k141_19637_1 396588.Tgr7_2286 1.07e-121 355.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales 135613|Chromatiales S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k141_7091_2 998088.B565_0582 1.93e-94 293.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1Y3VZ@135624|Aeromonadales 135624|Aeromonadales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_14780_1 1318628.MARLIPOL_14615 1.03e-154 445.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,4683Q@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the GSP D family rcpA - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - Secretin,T2SS-T3SS_pil_N k141_14780_2 1318628.MARLIPOL_14620 1.35e-162 469.0 COG4963@1|root,COG4963@2|Bacteria,1R5SM@1224|Proteobacteria,1RRFI@1236|Gammaproteobacteria 1236|Gammaproteobacteria U COG4963 Flp pilus assembly protein, ATPase CpaE tadZ - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - TadZ_N k141_14780_3 1318628.MARLIPOL_14625 1.54e-225 629.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,4644B@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4962 Flp pilus assembly protein, ATPase CpaF tadA - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_14780_4 1318628.MARLIPOL_14630 2.23e-130 380.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S7U3@1236|Gammaproteobacteria,46C3U@72275|Alteromonadaceae 1236|Gammaproteobacteria U Type II secretion system (T2SS), protein F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_14780_5 1318628.MARLIPOL_14635 2.96e-128 373.0 COG2064@1|root,COG2064@2|Bacteria,1RHHS@1224|Proteobacteria,1S61W@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_14780_6 1318628.MARLIPOL_14640 1.27e-69 219.0 COG5010@1|root,COG5010@2|Bacteria,1NA2M@1224|Proteobacteria,1SE2A@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Flp pilus assembly protein TadD, contains TPR repeats - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 k141_14780_8 1318628.MARLIPOL_14650 8.43e-108 343.0 COG4655@1|root,COG4655@2|Bacteria,1R41B@1224|Proteobacteria,1S49Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,Tad_C k141_14780_9 1318628.MARLIPOL_14655 6.91e-86 278.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S1KB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_4303_1 414684.RC1_2827 6.44e-42 159.0 COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3 k141_822_1 631362.Thi970DRAFT_01381 8.25e-112 340.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales 135613|Chromatiales C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2 k141_21703_2 40571.JOEA01000053_gene6818 8.31e-44 157.0 COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4E0VV@85010|Pseudonocardiales 201174|Actinobacteria L Integrase core domain - - - - - - - - - - - - HTH_21,rve k141_21703_3 1298593.TOL_1867 3.85e-51 164.0 COG2963@1|root,COG2963@2|Bacteria,1N1CG@1224|Proteobacteria,1SAIC@1236|Gammaproteobacteria,1XPKX@135619|Oceanospirillales 135619|Oceanospirillales L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_18962_2 243233.MCA1976 8.64e-100 315.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XE70@135618|Methylococcales 135618|Methylococcales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_4304_1 697282.Mettu_2580 6.5e-65 219.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XEQK@135618|Methylococcales 135618|Methylococcales O Cytochrome c-type biogenesis protein CcmF ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_7810_1 857571.EA1_06851 7.71e-09 63.2 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,3NIXN@468|Moraxellaceae 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_7810_2 1278309.KB907103_gene1136 8.29e-101 295.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_7810_3 1278309.KB907103_gene1137 9.75e-100 291.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales 135619|Oceanospirillales S colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V k141_7810_4 1278309.KB907103_gene1138 0.0 887.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XHAH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_9861_1 794903.OPIT5_07190 6.73e-51 184.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,46URZ@74201|Verrucomicrobia,3K946@414999|Opitutae 414999|Opitutae T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_9861_2 670292.JH26_27240 2.43e-30 118.0 COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,1JSSN@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,Response_reg k141_9861_3 425104.Ssed_2865 2.78e-44 174.0 COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae 1236|Gammaproteobacteria T histidine kinase A domain protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - CHASE,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1 k141_7811_1 717774.Marme_3717 1.49e-13 76.6 COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,1XJX1@135619|Oceanospirillales 135619|Oceanospirillales U AAA domain - - - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR k141_823_1 765914.ThisiDRAFT_1039 3.66e-138 417.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_18963_1 1288826.MSNKSG1_05681 0.0 872.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4650M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 k141_7093_1 243233.MCA2253 2.12e-187 550.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XDWG@135618|Methylococcales 135618|Methylococcales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_15496_1 1121479.AUBS01000027_gene456 1.11e-133 387.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N k141_14072_1 279714.FuraDRAFT_1811 2.56e-23 97.1 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria 28216|Betaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_14072_2 1209072.ALBT01000033_gene1634 7.55e-08 58.5 COG0664@1|root,COG0664@2|Bacteria,1RKRH@1224|Proteobacteria,1S42Z@1236|Gammaproteobacteria,1FGQD@10|Cellvibrio 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_5726_1 1288826.MSNKSG1_15646 9.63e-286 803.0 COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,1T3BE@1236|Gammaproteobacteria,46D4Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_5726_2 225937.HP15_3863 7.1e-149 434.0 COG2199@1|root,COG3300@1|root,COG2199@2|Bacteria,COG3300@2|Bacteria,1RGCV@1224|Proteobacteria,1RZPM@1236|Gammaproteobacteria,469UT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Bacterial signalling protein N terminal repeat - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - GGDEF,MHYT k141_4305_1 1121035.AUCH01000015_gene2492 2.03e-205 595.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVQE@206389|Rhodocyclales 206389|Rhodocyclales T chemotaxis protein - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_4305_2 204773.HEAR3262 7.81e-22 97.8 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,473VA@75682|Oxalobacteraceae 28216|Betaproteobacteria NT methyl-accepting chemotaxis protein - - - ko:K03406,ko:K03776,ko:K05874,ko:K05875 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH k141_8504_1 1278309.KB907103_gene1084 2.65e-239 669.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XI1K@135619|Oceanospirillales 135619|Oceanospirillales I Poly(3-hydroxyalkanoate) synthetase - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N k141_11325_1 443152.MDG893_07720 2.87e-126 365.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,467P6@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_11325_2 270374.MELB17_00865 5.91e-83 256.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RZSX@1236|Gammaproteobacteria,46DGD@72275|Alteromonadaceae 1236|Gammaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_16872_1 1278309.KB907101_gene635 2.13e-122 358.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1XIW9@135619|Oceanospirillales 135619|Oceanospirillales OU peptidase sohB - - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_21722_2 203122.Sde_0010 2.64e-50 164.0 2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21722_4 1049564.TevJSym_bj00170 1.78e-113 343.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1J4FJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0018995,GO:0022610,GO:0030430,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0050789,GO:0051082,GO:0051704,GO:0061077,GO:0065007,GO:0101031,GO:1990220,GO:2000535 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_17556_1 2340.JV46_07570 4.86e-63 197.0 COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1J6R4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 k141_17556_2 1382359.JIAL01000001_gene1984 3.88e-50 176.0 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity - - - - - - - - - - - - CCP_MauG k141_107_1 338969.Rfer_0711 1.46e-70 227.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,4ABFN@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM mannose-6-phosphate isomerase, type II cpsB - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_107_2 439235.Dalk_1657 1.06e-71 227.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2MIHM@213118|Desulfobacterales 28221|Deltaproteobacteria M Polysaccharide biosynthesis protein - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_20388_1 1121918.ARWE01000001_gene3199 2.46e-06 50.4 COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg k141_20388_2 1335760.ASTG01000019_gene2740 3e-12 66.6 COG3804@1|root,COG3804@2|Bacteria,1NE6U@1224|Proteobacteria,2UHYI@28211|Alphaproteobacteria,2K6S8@204457|Sphingomonadales 204457|Sphingomonadales S Sensors of blue-light using FAD - - - - - - - - - - - - BLUF k141_10613_1 760117.JN27_08615 1.16e-122 361.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,47296@75682|Oxalobacteraceae 28216|Betaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_1526_1 298386.PBPRA0776 5.63e-38 149.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTC9@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - - - - - - - - - - MCPsignal,dCache_1 k141_4988_2 1232683.ADIMK_1329 4.66e-213 603.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,464AT@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_4988_3 1201293.AKXQ01000022_gene447 5.41e-28 120.0 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k141_4988_4 357804.Ping_1305 1.11e-27 107.0 COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,1S97W@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component - - - - - - - - - - - - PBP_like_2 k141_7110_1 1128912.GMES_0390 3.17e-12 65.5 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,467D6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaiL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09912 - - - - ko00000 - - iECW_1372.ECW_m0432,iWFL_1372.ECW_m0432 DUF2058 k141_7110_2 1286106.MPL1_04065 6.08e-22 89.7 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SCXD@1236|Gammaproteobacteria,4638S@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_7110_3 1121385.AQXW01000004_gene1271 6.75e-53 186.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,1ZWE2@145357|Dermacoccaceae 201174|Actinobacteria E B12 binding domain metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_108_1 323850.Shew_2140 3.05e-21 93.2 COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,1RMSD@1236|Gammaproteobacteria,2QB3M@267890|Shewanellaceae 1236|Gammaproteobacteria K WYL domain - - - - - - - - - - - - WYL k141_16155_1 1278309.KB907100_gene2205 9.5e-39 135.0 COG5285@1|root,COG5285@2|Bacteria,1PF68@1224|Proteobacteria,1RYF8@1236|Gammaproteobacteria,1XPMF@135619|Oceanospirillales 135619|Oceanospirillales Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH k141_16155_2 1278309.KB907100_gene2206 3.55e-61 196.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XHIK@135619|Oceanospirillales 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_16873_1 396588.Tgr7_0875 2.15e-88 286.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales 135613|Chromatiales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_4326_1 1249627.D779_2440 9.42e-134 388.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1WVWC@135613|Chromatiales 135613|Chromatiales K TIGRFAM RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_14796_1 666681.M301_2780 5.52e-101 308.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,2KMGD@206350|Nitrosomonadales 206350|Nitrosomonadales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 k141_2223_1 205918.Psyr_2106 7.39e-44 154.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1Z4VY@136849|Pseudomonas syringae group 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 DHO_dh k141_7111_1 105559.Nwat_0178 5.88e-18 81.3 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales 135613|Chromatiales S subfamily IA, variant 1 - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_7111_2 454957.IA64_09215 8.75e-26 105.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1X407@135614|Xanthomonadales 135614|Xanthomonadales J Responsible for synthesis of pseudouridine from uracil rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_13398_1 62928.azo2556 0.000146 49.7 COG0689@1|root,COG2304@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG0689@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QU09@1224|Proteobacteria 1224|Proteobacteria M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - Calx-beta,DUF4347,He_PIG,VWA_2 k141_19653_1 10756.DPOL_BPPH2 4.6e-08 60.5 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage 10239|Viruses S DNA polymerase type B, organellar and viral - GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039687,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k141_15513_1 1168067.JAGP01000001_gene1191 1.93e-109 334.0 COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1MUM1@1224|Proteobacteria,1RZKJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - 1.12.1.2,1.12.7.2 ko:K00533,ko:K18006 - - R00019 - ko00000,ko01000 - - - Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3 k141_4327_1 745411.B3C1_00230 1.66e-64 202.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,1J5W4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S DoxX - - - - - - - - - - - - DoxX k141_2931_1 713586.KB900536_gene1212 6.39e-15 72.8 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1WXAI@135613|Chromatiales 135613|Chromatiales H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_4989_1 1124780.ANNU01000032_gene1265 1.34e-132 392.0 COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,47K0W@768503|Cytophagia 976|Bacteroidetes S FAD dependent oxidoreductase - - - ko:K07137 - - - - ko00000 - - - FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2 k141_5747_1 572479.Hprae_0855 9.84e-34 133.0 COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WBKK@53433|Halanaerobiales 186801|Clostridia T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg,dCache_1 k141_12690_1 1120953.AUBH01000003_gene2172 1.19e-20 89.7 COG3913@1|root,COG3913@2|Bacteria,1QFVW@1224|Proteobacteria,1RSPG@1236|Gammaproteobacteria,46CYI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2094) - - - ko:K11890 ko02025,map02025 - - - ko00000,ko00001,ko02044 - - - DUF2094 k141_12690_2 1278309.KB907104_gene835 2.63e-79 261.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XI32@135619|Oceanospirillales 135619|Oceanospirillales N ImcF-related N-terminal domain - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N,OmpA k141_7112_1 1246995.AFR_07045 1.56e-13 74.3 COG3300@1|root,COG3300@2|Bacteria,2GMG6@201174|Actinobacteria,4DD5S@85008|Micromonosporales 201174|Actinobacteria T Bacterial signalling protein N terminal repeat - - - - - - - - - - - - MHYT k141_1528_1 395493.BegalDRAFT_2005 1.66e-57 189.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,460Q9@72273|Thiotrichales 72273|Thiotrichales EH PFAM Aminotransferase, class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_1528_2 1158762.KB898040_gene1501 5.98e-07 50.8 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales 135613|Chromatiales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_7828_1 1461579.CCNK01000031_gene1018 3.61e-38 136.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1Y6Y2@135625|Pasteurellales 135625|Pasteurellales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_10614_1 391038.Bphy_3851 3.48e-48 180.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,2VTF9@28216|Betaproteobacteria,1K0XB@119060|Burkholderiaceae 28216|Betaproteobacteria I Phosphoesterase PA-phosphatase related yabI_1 - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - LssY_C,PAP2,SNARE_assoc k141_10614_2 207954.MED92_17465 3.37e-06 48.1 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XII2@135619|Oceanospirillales 135619|Oceanospirillales H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_6403_1 1415755.JQLV01000001_gene3804 2.3e-101 306.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XI3H@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_844_1 435908.IDSA_10095 9.97e-193 546.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_844_2 243233.MCA2055 2.12e-107 317.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,1XE4U@135618|Methylococcales 135618|Methylococcales O PFAM 20S proteasome, A and B subunits - - - ko:K07395 - - - - ko00000 - - - - k141_16709_1 1255043.TVNIR_3387 8.08e-40 145.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - PLDc_2 k141_6267_1 1288826.MSNKSG1_10488 3.35e-56 181.0 COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,1S4NN@1236|Gammaproteobacteria,46CHB@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_6267_2 1288826.MSNKSG1_10483 0.0 899.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4659W@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1061 DNA or RNA helicases of superfamily II yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k141_14568_1 583345.Mmol_1370 3.22e-79 248.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KM17@206350|Nitrosomonadales 206350|Nitrosomonadales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_2774_1 118173.KB235914_gene2642 1.43e-25 109.0 COG5361@1|root,COG5361@2|Bacteria,1G1YW@1117|Cyanobacteria,1HBQ9@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_17408_1 396588.Tgr7_2051 1.99e-64 207.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales 135613|Chromatiales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_17408_2 545276.KB898730_gene1402 5.41e-23 91.3 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1WYAE@135613|Chromatiales 135613|Chromatiales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_18814_1 765914.ThisiDRAFT_1160 5.21e-80 246.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1WWKH@135613|Chromatiales 135613|Chromatiales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_18814_2 648757.Rvan_0305 1.02e-33 125.0 COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,2U3GA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1614) - - - - - - - - - - - - DUF1614 k141_695_1 1298608.JCM18900_1502 0.000229 43.1 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,3NKNN@468|Moraxellaceae 1236|Gammaproteobacteria P Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_695_2 1001585.MDS_3649 1.98e-11 68.2 2C3TN@1|root,32ZG7@2|Bacteria,1N6ZH@1224|Proteobacteria,1SEMF@1236|Gammaproteobacteria,1YI5Z@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17409_1 570952.ATVH01000011_gene456 2.23e-28 107.0 COG1580@1|root,COG1580@2|Bacteria,1RH5D@1224|Proteobacteria,2U9BF@28211|Alphaproteobacteria,2JST8@204441|Rhodospirillales 204441|Rhodospirillales N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_16711_2 1122137.AQXF01000001_gene2850 1.5e-35 129.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria 28211|Alphaproteobacteria I 3-hydroxyacyl-coa dehydrogenase hbdA - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_11780_1 1278309.KB907100_gene1901 4.09e-100 296.0 COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1XIEJ@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_11780_2 1278309.KB907100_gene1902 3.47e-31 109.0 2ENM2@1|root,33G8F@2|Bacteria,1NHSK@1224|Proteobacteria,1SHRE@1236|Gammaproteobacteria,1XMR4@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11780_3 1278309.KB907100_gene1903 2.15e-143 420.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1XI04@135619|Oceanospirillales 135619|Oceanospirillales L exonuclease recJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_6269_1 2340.JV46_03550 8.06e-141 416.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Transket_pyr,Transketolase_C,Transketolase_N k141_6836_1 1131553.JIBI01000005_gene2208 3.25e-17 85.9 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,372HA@32003|Nitrosomonadales 28216|Betaproteobacteria U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_20861_1 1288826.MSNKSG1_14127 6.84e-129 371.0 COG1732@1|root,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RN72@1236|Gammaproteobacteria,46AFM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) yehZ GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iE2348C_1286.E2348C_2278,iEC55989_1330.EC55989_2381,iECIAI39_1322.ECIAI39_0865,iECO103_1326.ECO103_2607,iECSE_1348.ECSE_2399 OpuAC k141_20861_2 1288826.MSNKSG1_14132 6.32e-183 509.0 COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,1RZJJ@1236|Gammaproteobacteria,469VB@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 k141_20861_3 1288826.MSNKSG1_14137 1.05e-110 318.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,1S63W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 k141_20861_4 1288826.MSNKSG1_14142 6e-287 786.0 COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,4695V@72275|Alteromonadaceae 1236|Gammaproteobacteria E Amino acid permease yjeH GO:0000099,GO:0000101,GO:0000102,GO:0001101,GO:0003333,GO:0003674,GO:0005215,GO:0005294,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015191,GO:0015238,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015821,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043200,GO:0043865,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:1901680,GO:1901682,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K03757,ko:K03759,ko:K16263 - - - - ko00000,ko02000 2.A.3.13,2.A.3.2 - - AA_permease_2 k141_696_1 1525715.IX54_04170 3.2e-37 133.0 COG1569@1|root,COG1569@2|Bacteria,1RCZE@1224|Proteobacteria,2U5DQ@28211|Alphaproteobacteria,2PWDF@265|Paracoccus 28211|Alphaproteobacteria S PIN domain - - - - - - - - - - - - PIN_3 k141_696_2 391613.RTM1035_10420 1.43e-66 208.0 COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2UQWK@28211|Alphaproteobacteria,46NMT@74030|Roseovarius 28211|Alphaproteobacteria E Peptidase, M48 family protein - - - ko:K07387 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M48 k141_18816_1 1278309.KB907101_gene700 5.83e-51 166.0 COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,1SAUP@1236|Gammaproteobacteria,1XMCW@135619|Oceanospirillales 135619|Oceanospirillales S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_18816_2 756067.MicvaDRAFT_0270 1.43e-10 60.1 2EA0N@1|root,33462@2|Bacteria,1GEKK@1117|Cyanobacteria,1HFYJ@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_2776_1 1249627.D779_2624 4.92e-38 136.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1WX0X@135613|Chromatiales 135613|Chromatiales Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_6837_1 1123393.KB891316_gene1426 1e-21 90.9 COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,2WEVJ@28216|Betaproteobacteria,1KT3T@119069|Hydrogenophilales 119069|Hydrogenophilales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_7658_2 1278309.KB907104_gene983 2.39e-165 470.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XHGV@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter substrate-binding protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_7658_3 1122599.AUGR01000029_gene3059 1.04e-239 679.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1XITF@135619|Oceanospirillales 135619|Oceanospirillales T Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK - 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_7658_4 1278309.KB907104_gene982 1.66e-207 577.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1XIU3@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - - - - - - - - - - - PFK k141_7658_5 1278309.KB907104_gene981 1.44e-126 365.0 COG0095@1|root,COG0095@2|Bacteria,1MYU3@1224|Proteobacteria,1SG08@1236|Gammaproteobacteria 1236|Gammaproteobacteria H biotin lipoate A B protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - - k141_7658_6 1278309.KB907104_gene980 1.55e-191 540.0 COG1485@1|root,COG1485@2|Bacteria,1MWH4@1224|Proteobacteria,1RMXV@1236|Gammaproteobacteria,1XIM6@135619|Oceanospirillales 135619|Oceanospirillales S AFG1-like ATPase - - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_7658_8 1278309.KB907104_gene978 4.85e-114 330.0 COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1XMAZ@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 k141_7658_9 1278309.KB907104_gene977 3.27e-140 397.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,1XHKZ@135619|Oceanospirillales 135619|Oceanospirillales S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B k141_7658_10 1278309.KB907104_gene976 7.46e-99 288.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1XKKS@135619|Oceanospirillales 135619|Oceanospirillales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_14569_1 1278309.KB907100_gene1949 5.19e-184 544.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIUY@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR,TPP_enzyme_C k141_9682_1 1123514.KB905899_gene1175 6.02e-112 340.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,4603S@72273|Thiotrichales 72273|Thiotrichales KLT Serine/threonine phosphatases, family 2C, catalytic domain - - - - - - - - - - - - PP2C_2,Pkinase k141_17411_1 1278309.KB907102_gene15 2.6e-118 353.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,1XH2I@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the mannose-6-phosphate isomerase type 2 family cpsB - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_11781_1 1244869.H261_02926 5.52e-30 124.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,2JRM7@204441|Rhodospirillales 204441|Rhodospirillales T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4 k141_18817_1 296591.Bpro_2468 3.91e-36 142.0 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG3829@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AC6T@80864|Comamonadaceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain bvgS2 - 2.7.13.3 ko:K07677,ko:K14978 ko02020,ko02026,map02020,map02026 M00474,M00663 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,Response_reg k141_9037_1 859657.RPSI07_2718 6.55e-57 196.0 COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2VMS5@28216|Betaproteobacteria,1K3TH@119060|Burkholderiaceae 28216|Betaproteobacteria S Bacterial protein of unknown function (DUF898) - - - - - - - - - - - - DUF898 k141_9037_2 269799.Gmet_0096 4.56e-71 231.0 COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,42TCQ@68525|delta/epsilon subdivisions,2WM2D@28221|Deltaproteobacteria,43S2X@69541|Desulfuromonadales 28221|Deltaproteobacteria O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_9037_3 765913.ThidrDRAFT_3170 6.27e-23 93.6 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1WX0X@135613|Chromatiales 135613|Chromatiales Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_20863_2 1410608.JNKX01000058_gene1798 5.81e-12 73.9 COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,2FRC8@200643|Bacteroidia,4AVRH@815|Bacteroidaceae 976|Bacteroidetes M rhs family-related protein and SAP-related protein K01238 - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_15234_1 1278309.KB907100_gene2345 3.72e-279 773.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate transport system permease protein - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_15234_2 1278309.KB907100_gene2344 4.82e-190 528.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XHJU@135619|Oceanospirillales 135619|Oceanospirillales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_15234_3 1278309.KB907100_gene2343 1.4e-154 436.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1XI5A@135619|Oceanospirillales 135619|Oceanospirillales P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k141_11807_1 545276.KB898724_gene1862 1.63e-244 677.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa k141_20128_3 396588.Tgr7_0350 5.71e-123 367.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales 135613|Chromatiales C reductase, alpha subunit - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_6889_2 1121940.AUDZ01000004_gene2585 1.09e-08 58.2 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SHDB@1236|Gammaproteobacteria,1XMNG@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 k141_9712_1 330214.NIDE0211 5.83e-52 171.0 COG3496@1|root,COG3496@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1365) - - 2.1.1.79 ko:K00574,ko:K09701 - - - - ko00000,ko01000 - - - DUF1365 k141_9712_2 887062.HGR_05449 4.93e-194 550.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae 28216|Betaproteobacteria S FAD dependent oxidoreductase - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase k141_9712_3 1458275.AZ34_07535 2.69e-44 152.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VMFC@28216|Betaproteobacteria,4AFKG@80864|Comamonadaceae 28216|Betaproteobacteria I Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_20129_1 870187.Thini_3264 7.1e-100 303.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,45ZYR@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_9713_1 323850.Shew_0808 0.000176 50.8 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,2Q914@267890|Shewanellaceae 1236|Gammaproteobacteria T PFAM histidine kinase, HAMP region domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_2,sCache_2 k141_6890_1 1288826.MSNKSG1_07043 6.78e-148 428.0 COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,4654Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) mdoG GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - ko:K03670 - - - - ko00000 - - - MdoG k141_6890_3 443152.MDG893_06004 4.14e-23 99.4 COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,1RMGX@1236|Gammaproteobacteria,465E9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2943 Membrane glycosyltransferase mdoH GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 - ko:K03669 - - - - ko00000,ko01000,ko01003,ko02000 4.D.3.1.1 GT2 - Glyco_trans_2_3,Glycos_transf_2 k141_11808_2 686340.Metal_0342 3.51e-88 289.0 COG2244@1|root,COG2244@2|Bacteria,1MV5E@1224|Proteobacteria,1RVM3@1236|Gammaproteobacteria,1XG4F@135618|Methylococcales 135618|Methylococcales U PFAM Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt_3 k141_9714_1 1278309.KB907101_gene350 2.73e-158 450.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,1XITY@135619|Oceanospirillales 135619|Oceanospirillales C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_9714_2 1278309.KB907101_gene349 4.91e-32 119.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XIDD@135619|Oceanospirillales 135619|Oceanospirillales S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_11809_1 1121013.P873_13245 2.11e-13 70.5 COG2805@1|root,COG5008@1|root,COG2805@2|Bacteria,COG5008@2|Bacteria,1MU3J@1224|Proteobacteria,1T393@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II/IV secretion system protein - - - ko:K12203 - - - - ko00000,ko02044 3.A.7.10.1,3.A.7.9.1 - - T2SSE k141_11809_2 159450.NH14_12305 3.4e-49 164.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae 28216|Betaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_6892_1 1121447.JONL01000002_gene1816 5.14e-94 312.0 COG5290@1|root,COG5290@2|Bacteria,1N3KW@1224|Proteobacteria,42PRG@68525|delta/epsilon subdivisions 1224|Proteobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - k141_11811_1 1237149.C900_04940 6.28e-65 217.0 COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia 976|Bacteroidetes S Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_9716_1 572477.Alvin_2598 2.66e-34 130.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_4094_1 1208321.D104_02075 3.34e-145 427.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XH4X@135619|Oceanospirillales 135619|Oceanospirillales C NADH flavin oxidoreductase NADH oxidase - - - ko:K21833 - - - - ko00000 - - - Oxidored_FMN,Pyr_redox_2 k141_4094_2 1278309.KB907099_gene2692 1.4e-125 357.0 COG1719@1|root,COG1719@2|Bacteria,1NP13@1224|Proteobacteria,1RQKJ@1236|Gammaproteobacteria,1XIEZ@135619|Oceanospirillales 135619|Oceanospirillales S V4R - - - - - - - - - - - - - k141_4094_3 1278309.KB907099_gene2691 2.69e-229 632.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RPBD@1236|Gammaproteobacteria,1XI79@135619|Oceanospirillales 135619|Oceanospirillales E Peptidase M19 - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 k141_4094_6 1122201.AUAZ01000023_gene2989 3.37e-175 540.0 COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1RY2M@1236|Gammaproteobacteria,46772@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_3 k141_6893_2 317025.Tcr_0012 2.67e-54 191.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_6894_1 367336.OM2255_06460 2.24e-76 251.0 COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0513 Superfamily II DNA and RNA helicases mgpS - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C k141_9718_1 1286106.MPL1_10397 5.17e-41 150.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,1SI1R@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_11812_1 402881.Plav_2041 4.04e-47 161.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,1JQM0@119043|Rhodobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon fixJ - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_20130_1 1278309.KB907100_gene1887 7.19e-102 317.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales 135619|Oceanospirillales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_20130_2 1278309.KB907100_gene1886 0.0 1044.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XHWP@135619|Oceanospirillales 135619|Oceanospirillales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_20130_3 1202962.KB907151_gene988 1.93e-19 90.9 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQAF@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,NIT k141_6896_1 272943.RSP_3597 6.83e-20 89.7 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,1FB9M@1060|Rhodobacter 28211|Alphaproteobacteria S Transporter associated domain tlyC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_6896_2 1337093.MBE-LCI_0541 1.29e-12 65.1 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2P8TQ@245186|Loktanella 28211|Alphaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_9719_1 765914.ThisiDRAFT_1983 2.34e-59 196.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX4M@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_7004_2 926562.Oweho_0070 1.06e-21 95.5 28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,1HWQW@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 k141_16759_1 1288826.MSNKSG1_17036 2.87e-130 370.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,466IN@72275|Alteromonadaceae 1236|Gammaproteobacteria H May be involved in the biosynthesis of molybdopterin moaB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_16759_2 1288826.MSNKSG1_17031 1.41e-197 554.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,4662Y@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_16051_1 1278309.KB907110_gene3222 2.75e-310 851.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1XH52@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_4902_1 1288826.MSNKSG1_16926 9.29e-10 59.3 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,4672V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2829 Outer membrane phospholipase A pldA GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0008970,GO:0009279,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044462,GO:0044464,GO:0045203,GO:0046872,GO:0046983,GO:0052689,GO:0071944 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_4201,iECUMN_1333.ECUMN_4347,iEcSMS35_1347.EcSMS35_4188 PLA1 k141_4902_2 1288826.MSNKSG1_16931 3.64e-70 212.0 28ZVJ@1|root,2ZMK3@2|Bacteria,1PABN@1224|Proteobacteria,1STJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4902_3 1288826.MSNKSG1_16936 9.91e-88 258.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,467R4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3245 Cytochrome c5 cyc - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - Cytochrome_CBB3 k141_4902_4 1288826.MSNKSG1_16941 0.0 1315.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4649F@72275|Alteromonadaceae 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_4902_5 1288826.MSNKSG1_16946 4.24e-278 768.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,469T1@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_14671_1 1122201.AUAZ01000005_gene625 1.93e-255 730.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,464J4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_20249_2 1278309.KB907101_gene759 3.52e-81 243.0 COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S3Z2@1236|Gammaproteobacteria,1XKBW@135619|Oceanospirillales 135619|Oceanospirillales I Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_3511_1 301.JNHE01000006_gene1069 9.75e-88 266.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1YE85@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_18854_1 1049564.TevJSym_aa00990 6.08e-66 223.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1J55N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT Chemotaxis protein histidine kinase cheA GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt k141_5601_1 521719.ATXQ01000010_gene41 8.65e-99 300.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase - - - - - - - - - - - - Fer4_14 k141_16760_1 344747.PM8797T_25196 2.83e-90 271.0 COG0024@1|root,COG0024@2|Bacteria,2J1QY@203682|Planctomycetes 203682|Planctomycetes J Methionine aminopeptidase - - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_1418_1 1121935.AQXX01000144_gene4525 6.4e-95 300.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XHTD@135619|Oceanospirillales 135619|Oceanospirillales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_10475_1 1179773.BN6_21530 2.01e-75 265.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_18855_1 1146883.BLASA_1643 3.44e-22 100.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4ERU7@85013|Frankiales 201174|Actinobacteria C NADH flavin oxidoreductase NADH oxidase - - - ko:K21833 - - - - ko00000 - - - NAD_binding_8,Oxidored_FMN,Pyr_redox_2 k141_13971_1 1278309.KB907099_gene2581 5.07e-124 367.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XHVH@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein-ubiquinone oxidoreductase etf - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_7702_1 1122201.AUAZ01000019_gene1788 3.23e-15 71.6 2ENZ5@1|root,33GK1@2|Bacteria,1NH2F@1224|Proteobacteria,1SIQ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12574_1 1278309.KB907104_gene819 2.17e-222 625.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1XJ12@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_19559_2 1336235.JAEG01000004_gene3752 3.17e-33 122.0 296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2U6CK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_3521_1 1123401.JHYQ01000002_gene2634 1.78e-103 323.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,45ZQ7@72273|Thiotrichales 72273|Thiotrichales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_16063_1 398580.Dshi_1340 3.37e-70 227.0 COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria,2U17B@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0591 Na proline symporter - - - - - - - - - - - - SSF k141_16772_1 666685.R2APBS1_3274 4.18e-81 259.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1X3X2@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_745_1 1038858.AXBA01000009_gene633 1.09e-28 109.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,3F168@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Nitroreductase family rutE - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k141_9801_1 1163617.SCD_n01676 1.41e-27 111.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria 28216|Betaproteobacteria EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_9801_2 1056820.KB900629_gene1620 1.73e-17 81.3 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,2PMV8@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E Alanine-glyoxylate amino-transferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_5622_1 1232683.ADIMK_2266 2.95e-44 150.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,466G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase yrfG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_5622_2 396588.Tgr7_2929 9.59e-68 208.0 COG0727@1|root,COG0727@2|Bacteria,1NXZE@1224|Proteobacteria,1SQVM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_35_1 1026882.MAMP_01019 2.11e-50 169.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1SYT9@1236|Gammaproteobacteria,463J6@72273|Thiotrichales 72273|Thiotrichales G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase - - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_35_2 765912.Thimo_2013 1.4e-53 181.0 COG3408@1|root,COG3408@2|Bacteria,1PGVT@1224|Proteobacteria,1SHCY@1236|Gammaproteobacteria,1WZTG@135613|Chromatiales 135613|Chromatiales G Alkaline and neutral invertase - - - - - - - - - - - - GDE_C,Glyco_hydro_100 k141_15387_1 1163617.SCD_n01412 6.89e-52 183.0 COG2199@1|root,COG2200@1|root,COG2203@1|root,COG3290@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,1RGKE@1224|Proteobacteria 1224|Proteobacteria T GAF domain - - 3.1.4.52 ko:K20962 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GAF_2,GGDEF,HWE_HK,PAS,PAS_3,PAS_4,PAS_8 k141_11212_1 395493.BegalDRAFT_1630 1.19e-179 512.0 COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RMV3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation nifK - 1.18.6.1 ko:K02591 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - DUF3364,Oxidored_nitro k141_12600_1 1231190.NA8A_14494 9.6e-31 117.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,43JUY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase k141_12600_2 1158756.AQXQ01000005_gene171 5.77e-48 158.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity VY92_00625 - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_1432_2 351348.Maqu_2474 6.12e-146 424.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,4641Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_20970_1 1278309.KB907103_gene1023 8.65e-129 399.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XIKY@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_5623_1 1461694.ATO9_20230 2.6e-45 159.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,2PCNK@252301|Oceanicola 28211|Alphaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_18867_2 1283300.ATXB01000001_gene33 6.25e-25 102.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XFW1@135618|Methylococcales 135618|Methylococcales P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_11888_1 572477.Alvin_2188 6.39e-88 273.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_11888_2 1005995.GTPT_1380 9.93e-22 89.4 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,4BUP2@82986|Tatumella 1236|Gammaproteobacteria O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB k141_18164_1 270374.MELB17_14301 6.32e-92 281.0 COG0438@1|root,COG0438@2|Bacteria,1NYTU@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k141_4913_1 1443113.LC20_00368 1.43e-36 134.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,41F7Y@629|Yersinia 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N k141_4913_2 1121921.KB898706_gene3313 3.37e-23 99.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,2PMQ1@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria JK 16S rRNA methyltransferase RsmB/F sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_10500_1 1237149.C900_04843 4.98e-60 194.0 COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,47XP8@768503|Cytophagia 976|Bacteroidetes E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_12601_1 1211112.ALJC01000131_gene3298 1.09e-54 191.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_5624_1 1278309.KB907110_gene3207 1.26e-93 294.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XI1F@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_2123_1 1123247.AUIJ01000003_gene1940 2.28e-83 275.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_7719_1 1266925.JHVX01000012_gene1725 7.66e-146 416.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,371YI@32003|Nitrosomonadales 28216|Betaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_7719_2 391038.Bphy_2895 3.61e-49 169.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1K3UE@119060|Burkholderiaceae 28216|Betaproteobacteria S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 k141_20972_1 768671.ThimaDRAFT_4579 1.44e-83 264.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1WXJT@135613|Chromatiales 135613|Chromatiales F Belongs to the 5'-nucleotidase family - - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C k141_21648_1 742733.HMPREF9469_05678 1.44e-09 59.3 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia 186801|Clostridia E Abc transporter - - - - - - - - - - - - ABC_tran,BCA_ABC_TP_C k141_21648_2 1232683.ADIMK_0294 7.69e-153 438.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1S8M4@1236|Gammaproteobacteria,469QN@72275|Alteromonadaceae 1236|Gammaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_21648_3 1232683.ADIMK_0293 2.83e-75 233.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RZ4X@1236|Gammaproteobacteria,46A9A@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13297_1 367336.OM2255_03730 2.1e-35 131.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_13297_2 551789.ATVJ01000002_gene2852 2.16e-21 94.0 COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,2U4AB@28211|Alphaproteobacteria,43XDW@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria cdsA2 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K09949 - - - - ko00000 - - - DUF1009 k141_11214_1 247633.GP2143_15876 5.5e-85 280.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1J501@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Adenylate cyclase cyaA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365 Adenyl_cycl_N,Adenylate_cycl k141_11889_2 1056512.D515_00594 8.47e-16 76.6 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,1Y2PC@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1249) yqiB - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_7026_1 1453501.JELR01000001_gene2245 2.3e-64 219.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_12602_1 1121011.AUCB01000044_gene3127 1.91e-17 80.9 COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1HY7T@117743|Flavobacteriia,23FXB@178469|Arenibacter 976|Bacteroidetes C Aldo/keto reductase family tas - - - - - - - - - - - Aldo_ket_red k141_7720_1 1120953.AUBH01000010_gene169 1.75e-29 117.0 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,4660B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_10501_1 1097668.BYI23_A013150 2.07e-29 111.0 COG5331@1|root,COG5331@2|Bacteria,1Q52X@1224|Proteobacteria,2VY63@28216|Betaproteobacteria 28216|Betaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_16065_1 264198.Reut_A1800 2.24e-115 342.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,1K1VT@119060|Burkholderiaceae 28216|Betaproteobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_2124_1 234826.AM1169 7.68e-09 63.2 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,47EYR@766|Rickettsiales 766|Rickettsiales O Cytochrome c-type biogenesis protein ccmF ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_18166_1 314345.SPV1_13177 3.99e-133 387.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel ynaI - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_20973_1 571166.KI421509_gene1073 5e-178 521.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_8406_1 1268239.PALB_5600 1.04e-48 165.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,2Q166@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_12603_2 1437882.AZRU01000001_gene2141 4.28e-25 102.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1YESP@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_7721_1 1260251.SPISAL_06805 1e-72 230.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales 135613|Chromatiales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_11215_1 1001585.MDS_4130 2.61e-91 280.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1YFKW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_5625_1 1278309.KB907101_gene739 0.0 1013.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1XH5W@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_9105_1 1469613.JT55_03400 1.7e-167 489.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,3FCND@34008|Rhodovulum 28211|Alphaproteobacteria O C-terminal, D2-small domain, of ClpB protein clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_14697_1 626887.J057_01294 7.53e-86 280.0 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,4650J@72275|Alteromonadaceae 1236|Gammaproteobacteria T response regulator rsbU - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_7722_1 367336.OM2255_07820 1.17e-92 283.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria 28211|Alphaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_2825_1 765910.MARPU_15720 9.47e-113 340.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales 135613|Chromatiales S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_17640_1 690597.JH730989_gene2978 2.75e-143 427.0 COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1YRY5@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,TrkA_N k141_5069_1 323261.Noc_0714 1.83e-121 353.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1WW8G@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA k141_5069_2 1452718.JBOY01000040_gene1935 1.12e-195 562.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_188_1 246200.SPO0520 1.95e-45 158.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,4NAGZ@97050|Ruegeria 28211|Alphaproteobacteria P Glutamate glutamine aspartate asparagine bztB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_7891_1 395493.BegalDRAFT_1820 3.24e-71 227.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_21815_1 768066.HELO_3753 3.41e-71 240.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XHTM@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_1608_1 519989.ECTPHS_03969 1.85e-79 243.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales 135613|Chromatiales S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_3009_1 1121374.KB891575_gene934 4.61e-10 59.3 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria 1236|Gammaproteobacteria D peptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 k141_3009_2 519989.ECTPHS_01329 5.31e-57 190.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_17641_1 414684.RC1_0958 1.81e-63 211.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,2JPMK@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_19064_1 105559.Nwat_1021 1.99e-81 266.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase, M16 - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_5070_1 1112217.PPL19_12978 5.38e-95 283.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_5832_3 768066.HELO_2643 1.4e-90 277.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k141_1609_1 1111135.HMPREF1248_1648 9.61e-11 66.6 COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4CX18@84998|Coriobacteriia 84998|Coriobacteriia S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt_3 k141_10693_1 1185876.BN8_00721 1.65e-23 91.3 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,47RU4@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bS21 family rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_10693_2 1279009.ADICEAN_01103 3.23e-16 77.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_17642_1 1121921.KB898706_gene3100 1.33e-105 316.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,2PMUA@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S GTP1/OBG obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_18334_1 1485545.JQLW01000007_gene786 4.4e-293 837.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria 1224|Proteobacteria E methionine synthase metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_7893_1 388401.RB2150_03289 2.94e-143 413.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,3ZGY7@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_20464_1 272568.GDI0639 1.7e-23 106.0 COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,2U33N@28211|Alphaproteobacteria,2JXFW@204441|Rhodospirillales 204441|Rhodospirillales M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k141_20464_2 349521.HCH_06797 2.18e-44 160.0 COG2314@1|root,COG4969@1|root,COG2314@2|Bacteria,COG4969@2|Bacteria,1RJJN@1224|Proteobacteria,1S6WP@1236|Gammaproteobacteria,1XMPG@135619|Oceanospirillales 135619|Oceanospirillales NU TM2 domain - - - - - - - - - - - - Pilin,TM2 k141_20464_3 493475.GARC_4457 5.84e-52 166.0 COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,1S8SG@1236|Gammaproteobacteria,4694E@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG2076 Membrane transporters of cations and cationic drugs emrE GO:0003674,GO:0005215,GO:0005326,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006805,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006855,GO:0006950,GO:0006970,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009410,GO:0009628,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015199,GO:0015220,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015651,GO:0015672,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0015871,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031460,GO:0033554,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071466,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072349,GO:0072488,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_20464_4 1278309.KB907099_gene2950 4.58e-128 372.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XI54@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_12778_1 1249627.D779_1804 2.21e-81 253.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_9930_2 633131.TR2A62_3583 1.32e-147 443.0 COG0457@1|root,COG1835@1|root,COG0457@2|Bacteria,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-transferase - - - - - - - - - - - - Acyl_transf_3 k141_9228_1 1122201.AUAZ01000011_gene1481 3.92e-59 191.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,467VC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_9228_2 1278309.KB907106_gene1351 9.19e-124 352.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1XHB3@135619|Oceanospirillales 135619|Oceanospirillales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_9228_3 1278309.KB907106_gene1350 6.63e-115 339.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHMY@135619|Oceanospirillales 135619|Oceanospirillales IQ catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_10694_1 1123501.KB902293_gene3494 1.97e-63 196.0 COG4101@1|root,COG4101@2|Bacteria,1RIFZ@1224|Proteobacteria,2VG5Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria G PFAM Cupin 2 conserved barrel domain protein - - - - - - - - - - - - Cupin_2 k141_18335_1 1286106.MPL1_08559 2.6e-71 219.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_18335_2 1249627.D779_2313 1.2e-06 48.9 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales 135613|Chromatiales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_5833_1 1469245.JFBG01000030_gene1528 1.06e-89 280.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1WWKI@135613|Chromatiales 135613|Chromatiales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_7 k141_190_1 518766.Rmar_0342 4.92e-103 319.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1FJVJ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_190_2 1298593.TOL_1661 9.72e-34 127.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1XJ4H@135619|Oceanospirillales 135619|Oceanospirillales E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_4410_1 509190.Cseg_1909 7.15e-08 59.3 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2KG6J@204458|Caulobacterales 204458|Caulobacterales M Cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_4410_2 1278309.KB907099_gene2900 6.01e-162 457.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1XJSM@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_4410_3 1278309.KB907099_gene2901 8.47e-98 297.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1XHT8@135619|Oceanospirillales 135619|Oceanospirillales S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase k141_3701_2 519989.ECTPHS_06272 1.67e-166 473.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-Transferase yqjG - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_3701_3 760192.Halhy_3496 1.05e-30 121.0 COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1ISFC@117747|Sphingobacteriia 976|Bacteroidetes S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_7894_1 357804.Ping_2914 1.05e-30 114.0 2BV15@1|root,32QDR@2|Bacteria,1RJ98@1224|Proteobacteria,1RYP4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_12779_1 371731.Rsw2DRAFT_1878 9.23e-57 184.0 COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,1FBTA@1060|Rhodobacter 28211|Alphaproteobacteria L Belongs to the DnaA family hda - - - - - - - - - - - Bac_DnaA k141_17643_1 1163617.SCD_n01211 2.96e-123 362.0 COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria 28216|Betaproteobacteria S DMSO reductase anchor subunit (DmsC) dmsC - - ko:K21309 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 - - - DmsC k141_9229_1 1002340.AFCF01000062_gene829 7.9e-99 294.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,34EQF@302485|Phaeobacter 28211|Alphaproteobacteria F Prokaryotic glutathione synthetase, N-terminal domain gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_1610_1 1260251.SPISAL_00640 1.17e-120 379.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales 135613|Chromatiales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_5073_1 395493.BegalDRAFT_0394 2.86e-107 325.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,45ZSM@72273|Thiotrichales 72273|Thiotrichales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_18336_1 870187.Thini_2730 1.98e-26 104.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,461N8@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_10695_2 1288826.MSNKSG1_00531 9.83e-44 152.0 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP k141_12780_1 1056820.KB900681_gene2859 1.1e-120 355.0 COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3385 FOG Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,DUF4372 k141_1611_1 1278309.KB907104_gene820 9.42e-112 332.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XK0P@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion, TssG - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_11405_1 1123393.KB891316_gene1613 1.55e-20 95.9 2C1AX@1|root,33GUX@2|Bacteria,1MZSH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_21842_1 1136163.M565_ctg5P0085 4.09e-12 67.0 COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,1RQNB@1236|Gammaproteobacteria,1XVQ0@135623|Vibrionales 135623|Vibrionales O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_21842_2 1268068.PG5_09240 8.87e-102 307.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Guanine deaminase guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_913_1 1288826.MSNKSG1_09873 3.84e-19 83.2 COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,1S6MS@1236|Gammaproteobacteria,46AW4@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_913_2 1288826.MSNKSG1_09868 0.0 1039.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_913_3 1288826.MSNKSG1_09863 5.25e-257 704.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,465H5@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1533 DNA repair photolyase - - - - - - - - - - - - Radical_SAM k141_913_4 1288826.MSNKSG1_09858 2.93e-81 260.0 COG0840@1|root,COG0840@2|Bacteria,1RFSF@1224|Proteobacteria,1S42G@1236|Gammaproteobacteria,46AWM@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_15584_1 1288826.MSNKSG1_11293 2.85e-251 691.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family phbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_15584_2 1288826.MSNKSG1_11298 1.2e-104 302.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,46713@72275|Alteromonadaceae 1236|Gammaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_15584_3 1288826.MSNKSG1_11303 2.1e-113 325.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,4679N@72275|Alteromonadaceae 1236|Gammaproteobacteria U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_15584_4 1288826.MSNKSG1_11308 8.76e-88 258.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4680N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0607 Rhodanese-related sulfurtransferase yibN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_15584_5 1288826.MSNKSG1_11313 0.0 1022.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,465AD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_15584_6 1288826.MSNKSG1_11318 3.76e-215 600.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,465VU@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG4942 Membrane-bound metallopeptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 k141_15584_7 1288826.MSNKSG1_11323 1.03e-312 854.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,465J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_15584_8 1288826.MSNKSG1_11328 5.81e-188 522.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,4678G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yibQ - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_17662_1 435908.IDSA_10100 8.13e-89 267.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PFAM 20S proteasome, A and B subunits - - - ko:K07395 - - - - ko00000 - - - Proteasome k141_8598_1 270374.MELB17_08306 2.58e-62 201.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,4640G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the DegT DnrJ EryC1 family spsC - - - - - - - - - - - DegT_DnrJ_EryC1 k141_8598_2 443152.MDG893_01240 3.27e-229 632.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,46620@72275|Alteromonadaceae 1236|Gammaproteobacteria M nucleoside-diphosphate sugar epimerases capD - 4.2.1.115 ko:K15894 ko00520,map00520 - R09697 RC02609 ko00000,ko00001,ko01000 - - - Polysacc_synt_2 k141_8598_4 1288826.MSNKSG1_08788 3.81e-30 114.0 COG3765@1|root,COG3765@2|Bacteria,1N2QS@1224|Proteobacteria,1SAAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Chain length determinant protein - - - - - - - - - - - - Wzz k141_10709_1 1278309.KB907099_gene3150 1.49e-79 239.0 28Q4G@1|root,2ZCMR@2|Bacteria,1RAB3@1224|Proteobacteria,1S2N3@1236|Gammaproteobacteria,1XKF4@135619|Oceanospirillales 135619|Oceanospirillales S Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function syd - - ko:K15723 - - - - ko00000 - - - Syd k141_10709_2 1278309.KB907099_gene3149 1.39e-91 272.0 COG3056@1|root,COG3056@2|Bacteria,1N9MP@1224|Proteobacteria,1SJE1@1236|Gammaproteobacteria,1XMRG@135619|Oceanospirillales 135619|Oceanospirillales M Uncharacterized lipoprotein - - - ko:K07286 - - - - ko00000 - - - Lipoprotein_16 k141_10709_3 1278309.KB907099_gene3148 2.64e-139 395.0 COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria,1XI76@135619|Oceanospirillales 135619|Oceanospirillales L 3-methyladenine DNA glycosylase - - - - - - - - - - - - Adenine_glyco k141_10709_4 1278309.KB907099_gene3147 1.34e-86 255.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XK7A@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_10709_5 1278309.KB907099_gene3146 2.4e-277 760.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XIFG@135619|Oceanospirillales 135619|Oceanospirillales E in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor alaA - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_10709_6 1278309.KB907099_gene3145 1.26e-70 213.0 2CU16@1|root,32SUH@2|Bacteria,1N3T8@1224|Proteobacteria,1SBCZ@1236|Gammaproteobacteria,1XKTF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10709_7 1278309.KB907099_gene3143 4.91e-64 202.0 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1XIWV@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction protein - - - - - - - - - - - - HDOD k141_14179_2 318161.Sden_3519 3.2e-11 62.8 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,2Q9TN@267890|Shewanellaceae 1236|Gammaproteobacteria O PFAM cytochrome c oxidase assembly protein CtaG Cox11 ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_4434_1 264201.pc0479 0.000111 45.4 COG1322@1|root,COG1322@2|Bacteria,2JFJ6@204428|Chlamydiae 204428|Chlamydiae S DNA recombination protein RmuC homolog rmuC - - ko:K09760 - - - - ko00000 - - - RmuC k141_4434_3 557598.LHK_02044 1.05e-76 243.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,2KQEW@206351|Neisseriales 206351|Neisseriales I squalene synthase HpnC hpnC - - - - - - - - - - - SQS_PSY k141_1630_1 311424.DhcVS_1095 2.27e-53 181.0 COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi,34D83@301297|Dehalococcoidia 301297|Dehalococcoidia C Radical SAM superfamily - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_7921_1 1278309.KB907101_gene293 2.78e-07 51.6 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XI3V@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the 5'-nucleotidase family - - - - - - - - - - - - 5_nucleotid_C k141_7921_2 545276.KB898727_gene376 2.44e-120 356.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_12096_2 1218352.B597_019520 5.78e-07 54.7 COG1974@1|root,COG1974@2|Bacteria,1PHU2@1224|Proteobacteria,1TB38@1236|Gammaproteobacteria,1Z3JG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K Peptidase S24-like - - - - - - - - - - - - HTH_3,Peptidase_S24 k141_8101_2 1112217.PPL19_16819 5e-43 144.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_12260_1 236097.ADG881_2183 1.29e-22 99.8 COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria,1T6HU@1236|Gammaproteobacteria,1XQQI@135619|Oceanospirillales 135619|Oceanospirillales M Surface antigen - - - - - - - - - - - - Bac_surface_Ag k141_13628_1 1288826.MSNKSG1_16026 8.23e-133 387.0 2E9Q2@1|root,333WE@2|Bacteria,1N872@1224|Proteobacteria,1SDWG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13628_2 1288826.MSNKSG1_16021 3.78e-94 281.0 2EKRM@1|root,33EFD@2|Bacteria,1NMVY@1224|Proteobacteria,1SITC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19878_1 981336.F944_01730 1.31e-111 357.0 COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,1RQH5@1236|Gammaproteobacteria,3NKDP@468|Moraxellaceae 1236|Gammaproteobacteria L CRISPR-associated helicase, Cas3 cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - ResIII k141_17819_1 1232683.ADIMK_0209 1.42e-93 288.0 28JFR@1|root,2Z99N@2|Bacteria,1R7C5@1224|Proteobacteria,1RZYU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2455_1 472759.Nhal_0482 1.63e-85 263.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1WX5B@135613|Chromatiales 135613|Chromatiales J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_2455_2 1158762.KB898044_gene309 2.24e-15 72.0 COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1WZ00@135613|Chromatiales 135613|Chromatiales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_2455_3 1500890.JQNL01000001_gene1312 2.85e-06 49.7 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1X3X2@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_8727_1 367336.OM2255_13017 6.67e-80 252.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_21323_1 1123020.AUIE01000010_gene1146 2.75e-94 297.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1SZFR@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_17085_1 396588.Tgr7_1082 3.08e-129 383.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales 135613|Chromatiales H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_14283_1 62928.azo1488 2.35e-23 94.4 2BWYB@1|root,32W1H@2|Bacteria,1N1MW@1224|Proteobacteria,2VUU1@28216|Betaproteobacteria,2KX47@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_14283_3 1134912.AJTV01000015_gene294 4.05e-17 80.9 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,2TU3E@28211|Alphaproteobacteria,371EM@31993|Methylocystaceae 28211|Alphaproteobacteria O ATPase family associated with various cellular activities (AAA) - - 3.6.4.6 ko:K06027 ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962 - - - ko00000,ko00001,ko01000,ko04131 1.F.1.1 - - AAA k141_15743_1 1112209.AHVZ01000032_gene2776 3.12e-37 137.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,3NMH5@468|Moraxellaceae 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_8117_1 1234364.AMSF01000055_gene1068 1.69e-54 184.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1X49V@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretory pathway pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_8117_2 754476.Q7A_644 1.47e-118 348.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,460AW@72273|Thiotrichales 72273|Thiotrichales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_9382_1 1288826.MSNKSG1_16076 0.0 1349.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,464P3@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_13630_1 1415756.JQMY01000001_gene1871 2.36e-97 294.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2PFB1@252301|Oceanicola 28211|Alphaproteobacteria S Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 k141_6609_1 292415.Tbd_1896 4.91e-39 141.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,1KRPH@119069|Hydrogenophilales 119069|Hydrogenophilales Q MlaC protein - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_6609_2 1198232.CYCME_0392 6.27e-63 203.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,4613M@72273|Thiotrichales 72273|Thiotrichales S Sodium Bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_7345_1 472759.Nhal_3420 1.51e-89 288.0 COG1674@1|root,COG3266@1|root,COG1674@2|Bacteria,COG3266@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales 135613|Chromatiales D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_1798_1 1027273.GZ77_05675 6.83e-34 127.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales 135619|Oceanospirillales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_1798_2 1279017.AQYJ01000029_gene3449 1.2e-38 145.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,464ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_10119_1 999611.KI421504_gene133 4.42e-54 183.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,27ZNQ@191028|Leisingera 28211|Alphaproteobacteria C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S etf - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_5940_1 398580.Dshi_0002 6.65e-292 842.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_20626_1 1121004.ATVC01000021_gene1793 2.42e-19 86.7 COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,2KREU@206351|Neisseriales 206351|Neisseriales K Bacterial transcriptional repressor C-terminal - - - - - - - - - - - - TetR_C_11,TetR_N k141_8118_1 1123368.AUIS01000003_gene1810 1.62e-55 183.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria 1236|Gammaproteobacteria T CBS-domain-containing membrane protein - - - ko:K07168 - - - - ko00000 - - - HPP k141_14284_1 195105.CN97_04985 1.7e-62 206.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_17820_1 870187.Thini_4105 2.1e-18 83.6 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,45ZQI@72273|Thiotrichales 72273|Thiotrichales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_19880_1 1123517.JOMR01000001_gene909 5.32e-105 312.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,45ZV7@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_16371_3 1049564.TevJSym_aq00500 1.66e-189 545.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1J4EZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281 GATase_6,SIS k141_10862_1 1278309.KB907105_gene1411 2.39e-122 363.0 COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,1RP80@1236|Gammaproteobacteria,1XH7C@135619|Oceanospirillales 135619|Oceanospirillales I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_10862_2 1278309.KB907105_gene1412 4.21e-259 718.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XID8@135619|Oceanospirillales 135619|Oceanospirillales KT Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,PAS,PAS_4,Sigma54_activat k141_10862_3 1278309.KB907105_gene1413 2.26e-134 384.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria,1XHPW@135619|Oceanospirillales 135619|Oceanospirillales E Branched-chain amino acid transport livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_10862_4 1278309.KB907105_gene1414 3.37e-172 481.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1XH78@135619|Oceanospirillales 135619|Oceanospirillales E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_10862_5 1278309.KB907105_gene1415 5.26e-245 679.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,1XHEI@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2,DUF3382 k141_10862_6 207954.MED92_12751 8.32e-188 525.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,1XH8D@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_10862_7 1278309.KB907105_gene1417 7.62e-238 657.0 COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,1RP5V@1236|Gammaproteobacteria,1XHUI@135619|Oceanospirillales 135619|Oceanospirillales E With LivFGHM is involved in the high affinity leucine transport - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_1086_1 395493.BegalDRAFT_0530 2.14e-06 48.1 2EGD6@1|root,33A4Z@2|Bacteria,1QGZY@1224|Proteobacteria,1TEH2@1236|Gammaproteobacteria,463BS@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_1086_2 1380390.JIAT01000010_gene4698 5.13e-55 201.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria 201174|Actinobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF k141_10120_1 95619.PM1_0217545 4.96e-68 224.0 COG4913@1|root,COG4913@2|Bacteria,1QW0C@1224|Proteobacteria,1T2PZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k141_5255_1 1278309.KB907102_gene199 0.0 1258.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XHNQ@135619|Oceanospirillales 135619|Oceanospirillales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,ResIII,SNF2_N k141_17087_1 765910.MARPU_13605 1.09e-53 183.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_4582_1 2340.JV46_03170 1.09e-43 155.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,1J9P0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O CAAX prenyl protease N-terminal, five membrane helices - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_20627_1 491952.Mar181_1614 5.51e-13 68.6 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XIPX@135619|Oceanospirillales 135619|Oceanospirillales S mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_20627_2 717774.Marme_2087 3.35e-55 177.0 2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,1S2ZX@1236|Gammaproteobacteria,1XQ0D@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF2760) - - - - - - - - - - - - DUF2760 k141_1087_2 870187.Thini_1075 1.58e-21 91.7 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,460DZ@72273|Thiotrichales 72273|Thiotrichales G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_2457_1 626887.J057_03130 1.77e-33 134.0 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1R46H@1224|Proteobacteria,1S1DF@1236|Gammaproteobacteria,46CHJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - HDOD,tRNA_edit k141_10863_1 1116472.MGMO_125c00200 1.64e-74 246.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XDTR@135618|Methylococcales 135618|Methylococcales G alpha beta alpha domain I - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_6610_1 1205680.CAKO01000010_gene3989 3.96e-09 57.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2JQ3Z@204441|Rhodospirillales 204441|Rhodospirillales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_6610_2 305900.GV64_18605 4.38e-19 89.7 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1XKGD@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_1799_1 643867.Ftrac_0240 1.6e-17 79.3 COG1396@1|root,COG1396@2|Bacteria,4PNPF@976|Bacteroidetes 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k141_1799_2 1121870.AUAA01000003_gene2570 1.15e-20 91.3 COG3550@1|root,COG3550@2|Bacteria,4NFYY@976|Bacteroidetes,1HXAI@117743|Flavobacteriia 976|Bacteroidetes S Pfam:HipA_N - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C k141_19246_1 1502852.FG94_03246 4.45e-52 176.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae 28216|Betaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_19246_2 1042375.AFPL01000043_gene1395 1.8e-122 365.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,46440@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_10121_1 469382.Hbor_17150 6.5e-16 84.7 COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,241AM@183963|Halobacteria 183963|Halobacteria P Sulfatase - - - - - - - - - - - - Sulfatase k141_1088_1 472759.Nhal_1635 2.88e-50 179.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales 135613|Chromatiales I PFAM SNARE associated Golgi protein - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc k141_7347_1 388401.RB2150_16904 9.29e-114 342.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,3ZGHE@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_9385_1 765914.ThisiDRAFT_0138 2.9e-44 155.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT CheW domain protein VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_3203_1 1278309.KB907102_gene202 0.0 1005.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XI40@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,NMT1,PAS,PAS_3,PAS_9 k141_3203_4 1278309.KB907102_gene204 0.0 1269.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria,1XHVF@135619|Oceanospirillales 135619|Oceanospirillales CK FMN_bind - - - ko:K19339 - - - - ko00000,ko03000 - - - FMN_bind,Fer4_5 k141_3203_5 1278309.KB907102_gene205 0.0 1211.0 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria,1XIUQ@135619|Oceanospirillales 135619|Oceanospirillales C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - k141_3203_6 1278309.KB907102_gene206 1.03e-211 597.0 COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria,1XJ1Q@135619|Oceanospirillales 135619|Oceanospirillales P Domain present in carbohydrate binding proteins and sugar hydrolses - - - ko:K07218 - - - - ko00000 - - - NosD k141_3203_7 1278309.KB907102_gene207 8.92e-169 478.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RY6M@1236|Gammaproteobacteria,1XH4Z@135619|Oceanospirillales 135619|Oceanospirillales V ATPases associated with a variety of cellular activities - - - ko:K19340 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC_tran k141_3203_8 1278309.KB907102_gene208 2.18e-164 463.0 COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria,1XHFC@135619|Oceanospirillales 135619|Oceanospirillales S ABC-2 family transporter protein - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2 k141_3203_9 1278309.KB907102_gene209 6.06e-90 267.0 COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,1S7G3@1236|Gammaproteobacteria,1XRNX@135619|Oceanospirillales 135619|Oceanospirillales C NosL - - - ko:K19342 - - - - ko00000 - - - NosL k141_3203_10 1278309.KB907102_gene210 2.03e-92 280.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1XRU4@135619|Oceanospirillales 135619|Oceanospirillales S FOG TPR repeat - - - - - - - - - - - - Peptidase_C39_2,Peptidase_C70,TPR_16,TPR_8 k141_15000_1 1140.Synpcc7942_1653 7.02e-98 301.0 COG0371@1|root,COG0371@2|Bacteria,1GD1H@1117|Cyanobacteria,1H0EU@1129|Synechococcus 1117|Cyanobacteria C Iron-containing alcohol dehydrogenase - - 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 - R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 - - - Fe-ADH k141_15000_2 1168065.DOK_15074 9.76e-71 228.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,1J4US@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_17822_1 717773.Thicy_1209 7.96e-33 122.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,461Y4@72273|Thiotrichales 72273|Thiotrichales S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_5941_1 1288826.MSNKSG1_01768 3.69e-27 103.0 COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,1S27B@1236|Gammaproteobacteria,4672C@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k141_5941_2 1288826.MSNKSG1_01763 6.81e-208 578.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,466DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPases (G3E family) yeiR GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - - - - - - - - - - CobW_C,cobW k141_8120_1 1288826.MSNKSG1_10113 2.04e-18 82.0 COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,466U0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B asrB - - ko:K16951 ko00920,ko01120,map00920,map01120 - R00858,R10146 RC00065 ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_8120_2 1288826.MSNKSG1_10118 3.7e-109 314.0 COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria,1S7IH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding k141_8120_3 1288826.MSNKSG1_10123 6.19e-212 589.0 COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,466GD@72275|Alteromonadaceae 1236|Gammaproteobacteria S 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 k141_5257_1 314232.SKA53_05980 6.4e-172 510.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family soxA - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_18485_1 1288826.MSNKSG1_04136 1.75e-51 167.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_18485_2 1288826.MSNKSG1_04141 5.89e-187 520.0 COG1192@1|root,COG1192@2|Bacteria,1MVEZ@1224|Proteobacteria,1RPWA@1236|Gammaproteobacteria,465CH@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_18485_3 1288826.MSNKSG1_04146 8.97e-75 223.0 COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,468CS@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqcC GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - DUF446 k141_18485_4 1288826.MSNKSG1_04151 7.07e-186 518.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,465GA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_18485_5 1288826.MSNKSG1_04156 2.47e-296 825.0 COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria,465VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_1115_1 397945.Aave_0060 5.81e-77 239.0 COG0702@1|root,COG0702@2|Bacteria,1PM6M@1224|Proteobacteria,2VMCW@28216|Betaproteobacteria 28216|Betaproteobacteria GM Nad-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase k141_6627_1 314345.SPV1_08456 0.0 1008.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria 1224|Proteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - - - - - - - - - - XFP,XFP_N k141_12276_1 1288826.MSNKSG1_14097 1.35e-265 742.0 COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,464WG@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation ycaO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_12276_2 1288826.MSNKSG1_14107 4.93e-89 260.0 COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S84U@1236|Gammaproteobacteria,4679S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_8738_1 765914.ThisiDRAFT_0975 1.17e-21 99.4 COG0642@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X2SE@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - - - - - - - - - - - CBS,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg k141_19890_1 1269813.ATUL01000008_gene1564 9.83e-12 70.1 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_19890_2 1182590.BN5_00127 9.55e-06 48.1 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1YEID@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Glycolate oxidase subunit GlcD glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 FAD-oxidase_C,FAD_binding_4 k141_4729_1 426114.THI_3374 2.85e-20 96.3 COG4585@1|root,COG4585@2|Bacteria,1R8DN@1224|Proteobacteria,2VPJ9@28216|Betaproteobacteria,1KKHD@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c,HisKA_3 k141_11667_1 1163617.SCD_n02914 4.21e-49 166.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria 28216|Betaproteobacteria M epimerase dehydratase - - 5.1.3.6,5.1.3.7 ko:K02473,ko:K08679 ko00520,ko01100,map00520,map01100 - R00418,R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_18628_1 1278309.KB907100_gene1956 5.74e-92 279.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XMZ2@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 k141_9500_1 754477.Q7C_2167 5.93e-30 115.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RNRI@1236|Gammaproteobacteria,4629P@72273|Thiotrichales 72273|Thiotrichales I PFAM Squalene phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_9500_2 159087.Daro_2707 1.12e-27 112.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,2KVAB@206389|Rhodocyclales 206389|Rhodocyclales H squalene-associated FAD-dependent desaturase - - - - - - - - - - - - Amino_oxidase k141_10265_1 713586.KB900536_gene2946 1.8e-34 122.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales 135613|Chromatiales J Belongs to the HSP15 family - - - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_6055_1 1415778.JQMM01000001_gene1963 1.81e-133 397.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_12420_1 335659.S23_62030 1.18e-38 148.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JVPA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF_2,GGDEF k141_5419_1 382464.ABSI01000022_gene475 5.43e-84 254.0 COG1272@1|root,COG1272@2|Bacteria,46T25@74201|Verrucomicrobia,2IVQU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Haemolysin-III related - - - - - - - - - - - - HlyIII k141_5419_2 1117318.PRUB_13796 2.42e-54 174.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,2Q2GU@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_4730_1 398527.Bphyt_0898 9.72e-43 155.0 COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,1K0JV@119060|Burkholderiaceae 28216|Betaproteobacteria H PFAM UbiA prenyltransferase - - - - - - - - - - - - HAD,UbiA k141_6716_1 1232410.KI421414_gene2847 7.04e-27 115.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales 28221|Deltaproteobacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N k141_17225_1 1288826.MSNKSG1_08653 5.36e-135 386.0 2DR20@1|root,339U3@2|Bacteria,1NI48@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_17225_2 1288826.MSNKSG1_08658 1.25e-226 626.0 COG1776@1|root,COG2201@1|root,COG1776@2|Bacteria,COG2201@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,465BA@72275|Alteromonadaceae 1236|Gammaproteobacteria NT response regulator cheC - - - - - - - - - - - Response_reg k141_13789_1 765910.MARPU_13575 4e-108 323.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WWR6@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator, LysR - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_22118_1 1278309.KB907104_gene909 8.6e-167 477.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XIJ4@135619|Oceanospirillales 135619|Oceanospirillales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_9501_1 396588.Tgr7_0941 1.12e-85 275.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales 135613|Chromatiales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_21458_1 1126627.BAWE01000005_gene6108 1.62e-20 91.7 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria,3K0RD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SapC - - - - - - - - - - - - SapC k141_21458_2 1278309.KB907104_gene815 4.02e-16 77.0 COG3515@1|root,COG3515@2|Bacteria,1MWDQ@1224|Proteobacteria,1RQXI@1236|Gammaproteobacteria,1XMPX@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ vasJ - - ko:K11910 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - ImpA_N,T6SS_VasJ k141_8823_1 349124.Hhal_0092 6.57e-14 70.5 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1WWXS@135613|Chromatiales 135613|Chromatiales P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU k141_8823_2 314278.NB231_00994 3.22e-36 137.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales 135613|Chromatiales G pfam mofrl - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_1917_1 998088.B565_3284 5.28e-30 108.0 COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria,1Y4R9@135624|Aeromonadales 135624|Aeromonadales S DNA-binding protein VF530 - - - - - - - - - - - - VF530 k141_1917_2 425104.Ssed_3773 2.61e-148 429.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,2QECY@267890|Shewanellaceae 1236|Gammaproteobacteria P Metallo-beta-lactamase superfamily blh - - - - - - - - - - - Lactamase_B,Rhodanese k141_1917_5 1190606.AJYG01000168_gene3934 1.87e-21 89.0 2E6Y2@1|root,331HC@2|Bacteria,1N7EH@1224|Proteobacteria,1SE1K@1236|Gammaproteobacteria,1Y12N@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_1917_6 1278309.KB907101_gene709 5.42e-45 147.0 2CBEP@1|root,32RT7@2|Bacteria,1MZXD@1224|Proteobacteria,1SCAX@1236|Gammaproteobacteria,1XM50@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6056_1 243159.AFE_0937 1.09e-111 335.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,2NCF3@225057|Acidithiobacillales 225057|Acidithiobacillales C Nickel-dependent hydrogenase - - - - - - - - - - - - NiFeSe_Hases k141_18630_1 292414.TM1040_2114 4.32e-122 361.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S A circularly permuted ATPgrasp MA20_32420 - - - - - - - - - - - CP_ATPgrasp_2 k141_8232_1 640081.Dsui_0818 1.83e-07 59.7 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,2KUKQ@206389|Rhodocyclales 206389|Rhodocyclales S protein containing LysM domain - - - - - - - - - - - - LysM k141_8232_2 395493.BegalDRAFT_0800 1.79e-28 107.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_15126_1 1202962.KB907161_gene314 2.7e-130 387.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2,HEAT_2 k141_15126_2 1249627.D779_3420 6.45e-150 430.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1WX99@135613|Chromatiales 135613|Chromatiales U Belongs to the binding-protein-dependent transport system permease family - - - ko:K11961 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_12421_1 713586.KB900536_gene2215 1.66e-16 76.3 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1WZ2H@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_8253_2 225937.HP15_2389 4.08e-264 730.0 COG0438@1|root,COG0438@2|Bacteria,1NRYT@1224|Proteobacteria 1224|Proteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k141_18652_2 689781.AUJX01000007_gene739 8.85e-13 75.5 COG0226@1|root,COG0226@2|Bacteria,1VT8I@1239|Firmicutes,24IAW@186801|Clostridia,2PS1B@265975|Oribacterium 186801|Clostridia P PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_22136_1 1123392.AQWL01000006_gene709 5.41e-69 219.0 COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria,1KSIM@119069|Hydrogenophilales 119069|Hydrogenophilales C Domain of unknown function DUF302 - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_15882_1 1380394.JADL01000007_gene4475 4.81e-37 128.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2UFK9@28211|Alphaproteobacteria,2JUAG@204441|Rhodospirillales 204441|Rhodospirillales S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_15882_2 426355.Mrad2831_3800 2.11e-27 107.0 COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2TU8Z@28211|Alphaproteobacteria,1JTH5@119045|Methylobacteriaceae 28211|Alphaproteobacteria P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_11670_1 1479237.JMLY01000001_gene287 2.82e-36 137.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4664T@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC transporter transmembrane region ygaD - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_14400_1 1333507.AUTQ01000260_gene3655 4.45e-126 375.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,2PZNH@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Belongs to the glutamate synthase family gltB - - - - - - - - - - - Glu_synthase k141_19375_1 2340.JV46_16140 1.21e-51 168.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1J5V2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_7520_1 1278309.KB907101_gene585 3.97e-103 308.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XI78@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_7520_2 1278309.KB907101_gene586 2.93e-133 387.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,1XID3@135619|Oceanospirillales 135619|Oceanospirillales C carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_1269_1 633131.TR2A62_1021 1.78e-58 191.0 COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TQXV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator gltR - - - - - - - - - - - HTH_1,LysR_substrate k141_6081_1 1278309.KB907099_gene2461 7.17e-235 647.0 COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,1XITU@135619|Oceanospirillales 135619|Oceanospirillales I Hydroxymethylglutaryl-coenzyme A reductase - - - - - - - - - - - - HMG-CoA_red k141_6081_2 1278309.KB907099_gene2462 1.89e-67 213.0 COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,1RP1W@1236|Gammaproteobacteria,1XJ1Z@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - - - - - - - - - - - FMN_dh k141_5436_2 1288826.MSNKSG1_14112 1.11e-157 444.0 COG1174@1|root,COG1174@2|Bacteria,1MX8D@1224|Proteobacteria,1RSDR@1236|Gammaproteobacteria,46AZ3@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1174 ABC-type proline glycine betaine transport systems, permease component yehW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iEC042_1314.EC042_2361,iECUMN_1333.ECUMN_2462 BPD_transp_1 k141_5436_3 1288826.MSNKSG1_14117 1.49e-221 611.0 COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria,469HM@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1125 ABC-type proline glycine betaine transport systems, ATPase components yehX GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iECED1_1282.ECED1_2573,iEcE24377_1341.EcE24377A_2418,iPC815.YPO1198 ABC_tran,CBS k141_19997_1 1288826.MSNKSG1_02128 5.83e-67 216.0 2C2XP@1|root,32WP3@2|Bacteria,1N3V4@1224|Proteobacteria,1SBUM@1236|Gammaproteobacteria,46DH5@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18008_1 384765.SIAM614_13943 6.89e-73 233.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family gabD6 - - ko:K15786 ko00260,map00260 - R09805 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_18008_2 1123360.thalar_01550 1.91e-116 345.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.76 ko:K15785 ko00260,map00260 - R06977 RC00006,RC00062 ko00000,ko00001,ko01000 - - - Aminotran_3 k141_8842_1 717774.Marme_1563 5.5e-116 343.0 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,1S7P2@1236|Gammaproteobacteria,1XS56@135619|Oceanospirillales 135619|Oceanospirillales E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_17244_1 1278309.KB907102_gene165 3.85e-23 97.4 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1XH65@135619|Oceanospirillales 135619|Oceanospirillales L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,Flavi_DEAD,HA2,Helicase_C,HrpB_C k141_17244_2 1042377.AFPJ01000009_gene234 4.87e-108 322.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T2B5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_18653_1 1304275.C41B8_13395 1.9e-40 146.0 COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria 1224|Proteobacteria P phosphate transport regulator (Distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_10288_1 1255043.TVNIR_2713 2.84e-39 148.0 COG3850@1|root,COG3850@2|Bacteria,1R2CG@1224|Proteobacteria,1T5KV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_22137_1 1122135.KB893157_gene254 2.92e-59 193.0 COG0075@1|root,COG0075@2|Bacteria,1QM2D@1224|Proteobacteria,2TSQ5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0075 serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - - - - - - - - - - Aminotran_5 k141_22137_2 391626.OAN307_c15540 2.33e-49 160.0 COG1522@1|root,COG1522@2|Bacteria,1RAP6@1224|Proteobacteria,2U5FX@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator, AsnC family - - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_9518_1 1288826.MSNKSG1_01623 2.77e-99 293.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,4674U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the MtfA family mtfA GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_9518_2 1288826.MSNKSG1_01618 1.25e-45 147.0 2CC9P@1|root,331C0@2|Bacteria,1NEFX@1224|Proteobacteria,1SEIY@1236|Gammaproteobacteria,46BU5@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit - - - - - - - - - - - - - k141_9518_3 1288826.MSNKSG1_01613 1.93e-152 430.0 COG0702@1|root,COG0702@2|Bacteria,1R8B9@1224|Proteobacteria,1S2S7@1236|Gammaproteobacteria,46A87@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 k141_9518_4 351348.Maqu_1067 1.52e-20 87.0 COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,467B2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitroreductase family nfnB - 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_13116_1 1278309.KB907099_gene2776 2.26e-161 460.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_2597_1 768671.ThimaDRAFT_2533 5.51e-95 286.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 135613|Chromatiales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_7521_1 1122927.KB895423_gene3736 1.31e-05 47.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HD2N@91061|Bacilli,26R1F@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_7521_2 1121448.DGI_0543 2.18e-41 140.0 COG0745@1|root,COG0745@2|Bacteria,1MZGI@1224|Proteobacteria,42UM3@68525|delta/epsilon subdivisions,2WR2K@28221|Deltaproteobacteria,2MC1R@213115|Desulfovibrionales 28221|Deltaproteobacteria T response regulator, receiver - - - - - - - - - - - - Response_reg k141_1937_1 870187.Thini_2730 7.15e-50 166.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,461N8@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_8255_1 62928.azo2450 1.86e-38 147.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGMG@28216|Betaproteobacteria,2KXYR@206389|Rhodocyclales 206389|Rhodocyclales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Response_reg k141_13810_1 1278309.KB907108_gene1604 0.0 979.0 COG3350@1|root,COG3350@2|Bacteria,1MWWK@1224|Proteobacteria,1RMN1@1236|Gammaproteobacteria,1XIIH@135619|Oceanospirillales 135619|Oceanospirillales S Methane/Phenol/Toluene Hydroxylase - - - - - - - - - - - - Phenol_Hydrox,YHS k141_13810_2 1278309.KB907108_gene1605 2.49e-55 172.0 2CJVU@1|root,32S7J@2|Bacteria,1N03Q@1224|Proteobacteria,1S8ZH@1236|Gammaproteobacteria,1XKM5@135619|Oceanospirillales 135619|Oceanospirillales Q MmoB/DmpM family - - - - - - - - - - - - MmoB_DmpM k141_13810_3 1278309.KB907108_gene1606 7.53e-217 600.0 2DB9W@1|root,2Z7Z9@2|Bacteria,1MZFV@1224|Proteobacteria,1RRZT@1236|Gammaproteobacteria,1XI93@135619|Oceanospirillales 135619|Oceanospirillales S Methane/Phenol/Toluene Hydroxylase - - - - - - - - - - - - Phenol_Hydrox k141_14401_1 870187.Thini_0595 8.83e-92 293.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales 72273|Thiotrichales P heavy metal translocating P-type ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_547_1 686340.Metal_1537 6.19e-240 676.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XE1C@135618|Methylococcales 135618|Methylococcales J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_6082_1 1255043.TVNIR_2826 1.48e-28 113.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1SYT9@1236|Gammaproteobacteria,1X25R@135613|Chromatiales 135613|Chromatiales G PFAM glucosamine galactosamine-6-phosphate isomerase - - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_18009_2 1523503.JPMY01000028_gene304 4.84e-21 85.5 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_13117_1 521719.ATXQ01000004_gene1831 3.83e-14 72.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1YEPM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_12439_1 1121875.KB907553_gene20 1.75e-100 306.0 COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_15885_1 243233.MCA0260 6.49e-24 94.0 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the BolA IbaG family yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - - - - - - - - - - BolA k141_5437_1 1232683.ADIMK_0303 1.24e-122 354.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria,46533@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - 4.2.1.132,4.2.1.80 ko:K18364 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02601,R05864 RC00750,RC02676 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_11018_1 1278309.KB907100_gene2144 1.02e-18 82.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,1XM11@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_11018_2 519989.ECTPHS_10291 5.72e-40 135.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1WZT2@135613|Chromatiales 135613|Chromatiales H Pterin 4 alpha carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_11018_3 1278309.KB907100_gene2146 1.02e-49 158.0 2EANF@1|root,334QY@2|Bacteria,1N8X0@1224|Proteobacteria,1SCTI@1236|Gammaproteobacteria,1XQRT@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11018_4 1278309.KB907100_gene2147 7.76e-52 168.0 COG3783@1|root,COG3783@2|Bacteria 2|Bacteria C electron transfer activity cybC - - ko:K15536 - - - - ko00000 - - - Cytochrom_B562 k141_18010_1 1121875.KB907563_gene4 5.04e-92 271.0 2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia 976|Bacteroidetes S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - k141_6838_2 1278309.KB907100_gene1897 1.01e-63 203.0 COG0790@1|root,COG0790@2|Bacteria,1R5EJ@1224|Proteobacteria,1SM9R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_2062_1 1122599.AUGR01000013_gene673 1.78e-19 81.3 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,1XMI5@135619|Oceanospirillales 135619|Oceanospirillales S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG k141_2062_2 1278309.KB907102_gene78 5.33e-79 241.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XJYV@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE k141_16718_1 468059.AUHA01000002_gene883 1.06e-111 355.0 COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1IQ5H@117747|Sphingobacteriia 976|Bacteroidetes H CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_17417_1 102129.Lepto7375DRAFT_2519 3.37e-16 84.0 COG3409@1|root,COG3409@2|Bacteria,1GQNA@1117|Cyanobacteria 1117|Cyanobacteria M Domain of unknown function (DUF4157) - - - - - - - - - - - - DUF4157 k141_4059_1 391626.OAN307_c11530 1.55e-26 103.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG1076 DnaJ-domain-containing proteins 1 djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_4059_2 314265.R2601_19574 2.28e-49 163.0 COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG1247 Sortase and related acyltransferases yncA - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 k141_15242_1 1049564.TevJSym_ad01580 3.97e-92 301.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1J4G0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_14578_1 326442.PSHAb0289 1.14e-39 154.0 COG0642@1|root,COG2202@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q025@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,Response_reg k141_20085_1 765911.Thivi_2156 2.17e-25 106.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1WX5R@135613|Chromatiales 135613|Chromatiales I aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_20085_2 572477.Alvin_2601 6.52e-74 224.0 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,1RRM7@1236|Gammaproteobacteria,1X23M@135613|Chromatiales 135613|Chromatiales S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_17418_1 1403313.AXBR01000023_gene2415 8.51e-10 63.9 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus 91061|Bacilli M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,Trigger_C k141_19515_1 313612.L8106_06020 1.5e-44 171.0 COG0659@1|root,COG0659@2|Bacteria,1G3AY@1117|Cyanobacteria,1H9Q2@1150|Oscillatoriales 1117|Cyanobacteria P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp,cNMP_binding k141_2783_1 89187.ISM_14355 2.22e-100 299.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,46Q3G@74030|Roseovarius 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_2783_2 467661.RKLH11_2559 4.09e-69 213.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,3ZG4P@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 ko:K00338,ko:K03941 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 - - Fer4 k141_16719_1 1226994.AMZB01000117_gene2622 1.99e-93 293.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1YDPU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Amidase atzF - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_2063_1 375451.RD1_2527 1.02e-43 160.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2P1Y8@2433|Roseobacter 28211|Alphaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg k141_7665_1 1278309.KB907100_gene2253 1.71e-60 190.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XJCI@135619|Oceanospirillales 135619|Oceanospirillales L DNA-3-methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_7665_2 1278309.KB907100_gene2254 3.5e-51 162.0 COG3529@1|root,COG3529@2|Bacteria,1NC40@1224|Proteobacteria,1SEJF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S nucleic-acid-binding protein containing a Zn-ribbon domain - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_7665_3 1278309.KB907100_gene2255 0.0 1177.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XHC0@135619|Oceanospirillales 135619|Oceanospirillales E Oligopeptidase prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_7665_4 1278309.KB907100_gene2256 1.02e-101 297.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1XJC5@135619|Oceanospirillales 135619|Oceanospirillales S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - - - - - - - - - - Hexapep k141_9048_1 1122603.ATVI01000001_gene1923 2.22e-23 97.4 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1X432@135614|Xanthomonadales 135614|Xanthomonadales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_9048_2 1101195.Meth11DRAFT_0499 7.55e-22 95.9 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,2VXI0@28216|Betaproteobacteria,2KMZH@206350|Nitrosomonadales 206350|Nitrosomonadales S signal sequence binding - - - - - - - - - - - - - k141_9048_3 686340.Metal_1813 1.14e-36 134.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XEXY@135618|Methylococcales 135618|Methylococcales S SURF1-like protein - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_16720_1 1502852.FG94_00148 4.07e-35 133.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2WENQ@28216|Betaproteobacteria,472E8@75682|Oxalobacteraceae 28216|Betaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_2784_1 395494.Galf_2542 2.46e-13 67.8 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,44VZG@713636|Nitrosomonadales 28216|Betaproteobacteria S Belongs to the UPF0225 family ychJ - - ko:K09858 - - - - ko00000 - - - SEC-C k141_2784_2 857087.Metme_0484 1.55e-48 167.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XGHS@135618|Methylococcales 135618|Methylococcales G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_2064_2 644107.SL1157_2374 1.76e-14 73.2 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,4NA3T@97050|Ruegeria 28211|Alphaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_15244_2 395493.BegalDRAFT_2187 3.41e-42 147.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,462QD@72273|Thiotrichales 72273|Thiotrichales G Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_4061_2 519989.ECTPHS_12798 4.03e-29 109.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WVXA@135613|Chromatiales 135613|Chromatiales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_16721_1 1245471.PCA10_24180 9.63e-145 425.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1YFDU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Sulfatase atsA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase k141_20086_1 1123518.ARWI01000001_gene54 4.7e-117 357.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,4604B@72273|Thiotrichales 72273|Thiotrichales C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_20086_2 472759.Nhal_1890 7.38e-40 139.0 COG1818@1|root,COG1818@2|Bacteria,1NEZ5@1224|Proteobacteria 1224|Proteobacteria S THUMP - - - - - - - - - - - - THUMP k141_14581_1 1232683.ADIMK_3871 9.94e-102 298.0 COG1309@1|root,COG1309@2|Bacteria,1RBN0@1224|Proteobacteria,1S326@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator tetR9 - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_3,TetR_N k141_14581_2 1232683.ADIMK_3882 1.03e-73 223.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,1T03E@1236|Gammaproteobacteria,468KC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_9690_1 1278309.KB907100_gene2272 3.65e-118 351.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XHSI@135619|Oceanospirillales 135619|Oceanospirillales P Trk system potassium uptake protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_9690_2 1278309.KB907100_gene2273 8.28e-137 391.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,1XJS1@135619|Oceanospirillales 135619|Oceanospirillales M Lipid A biosynthesis acyltransferase lpxL2 - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_9690_3 1278309.KB907100_gene2274 8.37e-86 254.0 28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,1S270@1236|Gammaproteobacteria,1XJKV@135619|Oceanospirillales 135619|Oceanospirillales S Nucleoside 2-deoxyribosyltransferase YtoQ - - - - - - - - - - - - Nuc_deoxyri_tr3 k141_9690_4 1278309.KB907100_gene2275 2.6e-231 637.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XHG1@135619|Oceanospirillales 135619|Oceanospirillales J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e k141_9690_5 1278309.KB907100_gene2276 8.22e-57 193.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XH7W@135619|Oceanospirillales 135619|Oceanospirillales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_15245_1 1249627.D779_0301 2.84e-06 48.5 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales 135613|Chromatiales K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_15245_2 710111.FraQA3DRAFT_3454 2.03e-19 90.5 COG1999@1|root,COG1999@2|Bacteria,2GKF0@201174|Actinobacteria,4EVKF@85013|Frankiales 201174|Actinobacteria S SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_2787_1 857087.Metme_1124 8.64e-39 150.0 COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales 135618|Methylococcales T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - - - - - - - - - - CHASE8,HAMP,HATPase_c,HisKA,PAS_9,Response_reg k141_16722_1 686340.Metal_2963 1.91e-63 206.0 COG3272@1|root,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XEGF@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_9052_1 459495.SPLC1_S370790 9.78e-16 77.8 COG0604@1|root,COG0604@2|Bacteria,1FZW8@1117|Cyanobacteria,1H6ZN@1150|Oscillatoriales 1117|Cyanobacteria C COG0604 NADPH quinone reductase and related Zn-dependent - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_20087_1 1123401.JHYQ01000007_gene566 8.74e-90 280.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,46079@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_6840_1 443152.MDG893_05274 7.27e-31 124.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_6840_2 1049564.TevJSym_aj00030 3.85e-51 177.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,1J916@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4062_1 1123228.AUIH01000005_gene726 3.15e-25 103.0 28J26@1|root,2Z8YT@2|Bacteria,1R7S5@1224|Proteobacteria,1RNDH@1236|Gammaproteobacteria,1XMRH@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2914) - - - - - - - - - - - - DUF2914 k141_17419_1 440512.C211_15885 6.36e-16 75.1 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422 Thymidylat_synt k141_17419_2 29495.EA26_02625 4.29e-62 196.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XX0F@135623|Vibrionales 135623|Vibrionales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_17419_3 522306.CAP2UW1_4137 2.63e-92 281.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,1KPXN@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_17419_4 555778.Hneap_1280 1.17e-52 174.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,1SE7Z@1236|Gammaproteobacteria,1X0SS@135613|Chromatiales 135613|Chromatiales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_17419_5 1385517.N800_04220 4.36e-58 182.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1X6WU@135614|Xanthomonadales 135614|Xanthomonadales P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_17419_6 1123399.AQVE01000007_gene1097 6.1e-33 118.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_15247_1 1242864.D187_000126 5.6e-19 89.7 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,42TEI@68525|delta/epsilon subdivisions,2WPXF@28221|Deltaproteobacteria,2YUUZ@29|Myxococcales 28221|Deltaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,TAT_signal k141_14585_1 90814.KL370892_gene2318 1.61e-23 102.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1SN75@1236|Gammaproteobacteria,462AW@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_9053_1 519989.ECTPHS_02526 3.23e-97 291.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_15330_1 2340.JV46_22460 1.01e-64 209.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1J51J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG1760 L-serine deaminase - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_15330_2 1123393.KB891326_gene39 1.03e-07 54.3 2AG0A@1|root,3164B@2|Bacteria,1PWU2@1224|Proteobacteria,2WCCV@28216|Betaproteobacteria,1KTFP@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_15330_3 629265.PMA4326_05401 5.7e-102 309.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1Z6TM@136849|Pseudomonas syringae group 1236|Gammaproteobacteria O Belongs to the peptidase S1C family degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_20180_1 1168065.DOK_18665 5.8e-06 51.6 COG2928@1|root,COG2928@2|Bacteria,1RF26@1224|Proteobacteria,1S579@1236|Gammaproteobacteria,1J60W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 k141_20180_2 580332.Slit_2511 1.05e-16 80.9 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM secretion protein HlyD family protein - - - ko:K01993,ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_6969_1 553178.CAPGI0001_0044 2.21e-25 100.0 28PHV@1|root,2ZC86@2|Bacteria,4NTT8@976|Bacteroidetes,1I57K@117743|Flavobacteriia,1ET0J@1016|Capnocytophaga 976|Bacteroidetes - - - - - - - - - - - - - - - k141_20181_1 1288826.MSNKSG1_07513 7.33e-93 273.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,466TR@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6,DLH k141_20181_2 1288826.MSNKSG1_07508 4.6e-222 626.0 COG2199@1|root,COG3264@1|root,COG3264@2|Bacteria,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1SZ5Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria MT COG2199 FOG GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_4151_1 1288826.MSNKSG1_10713 4.38e-114 345.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_4151_2 1288826.MSNKSG1_10718 2.01e-68 207.0 COG0789@1|root,COG0789@2|Bacteria,1N0AR@1224|Proteobacteria,1SBDH@1236|Gammaproteobacteria,4695G@72275|Alteromonadaceae 1236|Gammaproteobacteria K MerR HTH family regulatory protein cbpM - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_4151_3 1288826.MSNKSG1_10723 2.21e-218 603.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4668N@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG2214 DnaJ-class molecular chaperone cbpA GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0005488,GO:0097159,GO:1901363 - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_20182_1 1121930.AQXG01000003_gene2497 8.67e-41 144.0 2CARY@1|root,32RRX@2|Bacteria,4NWQ6@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_20183_1 314271.RB2654_17941 1.9e-46 150.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k141_4152_1 998674.ATTE01000001_gene2423 2.2e-31 114.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_4152_2 1049564.TevJSym_aa00390 1.52e-111 328.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1J4UT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_4152_3 1121939.L861_16320 1.45e-65 209.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XHXP@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_20184_1 1237149.C900_03855 7.44e-79 249.0 COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes 976|Bacteroidetes S Glutamate-cysteine ligase family 2(GCS2) - - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 k141_4154_2 378806.STAUR_5412 1.78e-07 57.0 COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2YXRH@29|Myxococcales 28221|Deltaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 k141_4157_1 1123279.ATUS01000005_gene3161 1.12e-21 96.3 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1J5XQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S transport system, permease component ypjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C_asm k141_15332_1 1278309.KB907099_gene2489 0.0 893.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XISY@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,Response_reg k141_801_4 1278309.KB907100_gene1941 4.63e-52 165.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1XKZ3@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0125 (RnfH) family rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_801_5 1278309.KB907100_gene1942 5.89e-54 171.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1XKXP@135619|Oceanospirillales 135619|Oceanospirillales I Cyclase dehydrase - - - - - - - - - - - - Polyketide_cyc k141_8472_1 768671.ThimaDRAFT_3401 3.82e-26 105.0 2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria,1WZX3@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8472_2 870187.Thini_1275 1.43e-24 98.6 28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,1RS8I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18932_1 713586.KB900536_gene1933 6.99e-13 70.5 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X2AG@135613|Chromatiales 135613|Chromatiales T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc,PilZ k141_14763_1 998674.ATTE01000001_gene1948 8.3e-21 91.3 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,4607Y@72273|Thiotrichales 72273|Thiotrichales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_14763_2 1089547.KB913013_gene4345 1.79e-39 137.0 COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,47R93@768503|Cytophagia 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - DUF2147 k141_2182_2 760568.Desku_2253 2.02e-21 89.0 COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,261T9@186807|Peptococcaceae 186801|Clostridia S PFAM Appr-1-p processing ymdB - - - - - - - - - - - Macro k141_4279_1 1177154.Y5S_02427 9.03e-72 236.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1XJ9V@135619|Oceanospirillales 135619|Oceanospirillales D peptidase - - - - - - - - - - - - Peptidase_M23 k141_2887_2 313603.FB2170_11356 7.63e-20 90.1 2DBV7@1|root,2ZB9P@2|Bacteria,4NPQU@976|Bacteroidetes,1I3N9@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4386) - - - - - - - - - - - - DUF4386 k141_20354_1 1122194.AUHU01000004_gene1474 1.55e-15 77.8 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_20354_2 765914.ThisiDRAFT_0937 3.24e-25 99.4 COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1WW9G@135613|Chromatiales 135613|Chromatiales J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_18231_1 105559.Nwat_2327 8.11e-70 223.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1X07Y@135613|Chromatiales 135613|Chromatiales E TIGRFAM amidase, hydantoinase carbamoylase - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_18231_2 472759.Nhal_2226 2.38e-25 101.0 2EK1K@1|root,33DS2@2|Bacteria,1NI6I@1224|Proteobacteria,1SH8F@1236|Gammaproteobacteria,1X1BE@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_802_1 745411.B3C1_13633 3.72e-47 171.0 COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,1J83Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 k141_5714_1 1288826.MSNKSG1_08868 1.69e-114 336.0 28HEC@1|root,2Z7QS@2|Bacteria,1N54Y@1224|Proteobacteria,1SA2G@1236|Gammaproteobacteria,4654V@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5714_2 1288826.MSNKSG1_08863 5.27e-130 370.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_5714_3 1288826.MSNKSG1_08858 3.72e-203 563.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,464N6@72275|Alteromonadaceae 1236|Gammaproteobacteria NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02464,ko:K02654 ko03070,map03070 M00331 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15,3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_5714_4 1288826.MSNKSG1_08853 1.56e-39 141.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,465E5@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG1459 Type II secretory pathway, component PulF pilC GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_7070_1 519989.ECTPHS_10276 1.72e-38 142.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales 135613|Chromatiales H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_78_1 765913.ThidrDRAFT_4296 7.47e-135 396.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WWEY@135613|Chromatiales 135613|Chromatiales C FAD linked oxidase - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_11299_1 765911.Thivi_2368 5.45e-09 57.4 COG3378@1|root,COG4643@1|root,COG3378@2|Bacteria,COG4643@2|Bacteria,1PGQR@1224|Proteobacteria,1T6BM@1236|Gammaproteobacteria,1X1M4@135613|Chromatiales 135613|Chromatiales S Primase C terminal 2 (PriCT-2) - - - ko:K06919 - - - - ko00000 - - - PriCT_2 k141_12655_1 376686.Fjoh_3907 2.62e-30 118.0 COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1I3BR@117743|Flavobacteriia,2NYJF@237|Flavobacterium 976|Bacteroidetes C Belongs to the NiFe NiFeSe hydrogenase large subunit family - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases k141_12655_2 1131814.JAFO01000001_gene288 2.18e-26 107.0 COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,2TSH2@28211|Alphaproteobacteria,3F16B@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 hupC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Ni_hydr_CYTB k141_3602_1 1158756.AQXQ01000007_gene305 9.96e-08 58.5 COG2199@1|root,COG3706@2|Bacteria,1RDXH@1224|Proteobacteria,1S3QY@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_18933_2 1304885.AUEY01000052_gene1562 2.63e-25 99.0 COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2MKA4@213118|Desulfobacterales 28221|Deltaproteobacteria S Roadblock/LC7 domain mglB - - - - - - - - - - - Robl_LC7 k141_14055_1 519989.ECTPHS_06762 2.65e-22 104.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales 135613|Chromatiales S TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_11969_1 118173.KB235914_gene2643 1.01e-67 216.0 2DV1D@1|root,33THT@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_19617_1 1278309.KB907110_gene3159 1.6e-187 530.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XHNE@135619|Oceanospirillales 135619|Oceanospirillales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_9158_3 1288826.MSNKSG1_02921 0.0 963.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,464CV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_11990_1 1500259.JQLD01000014_gene1703 2.52e-23 105.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,4BC0C@82115|Rhizobiaceae 28211|Alphaproteobacteria V Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_18957_2 396588.Tgr7_0076 1.78e-74 243.0 COG2199@1|root,COG3706@2|Bacteria,1QUY1@1224|Proteobacteria,1SZ80@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,HAMP k141_20371_2 713586.KB900536_gene3079 3.94e-55 189.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1WX1A@135613|Chromatiales 135613|Chromatiales T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_19634_1 207954.MED92_08211 4.39e-111 339.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XJGP@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook protein flgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_9859_1 1469613.JT55_16645 2.13e-144 420.0 COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,2U18T@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC transporter substrate-binding protein - - - - - - - - - - - - SBP_bac_5 k141_17528_2 1123368.AUIS01000014_gene2288 3.71e-65 202.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,2NCUY@225057|Acidithiobacillales 225057|Acidithiobacillales T low molecular weight - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc k141_17528_3 768671.ThimaDRAFT_3700 1.83e-199 560.0 COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,1WXCD@135613|Chromatiales 135613|Chromatiales P TIGRFAM Arsenical-resistance protein - - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF k141_7807_2 1121035.AUCH01000007_gene460 1.77e-153 493.0 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVXP@206389|Rhodocyclales 206389|Rhodocyclales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS_3,PAS_7,PAS_9,Response_reg k141_7089_2 1278309.KB907101_gene669 1.15e-171 487.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1XHN4@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_7089_3 1278309.KB907101_gene668 3.05e-59 187.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1XK7S@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_1500_1 713586.KB900536_gene2882 8.02e-112 329.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1500_2 395493.BegalDRAFT_0242 3.88e-107 339.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales 72273|Thiotrichales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_6385_1 478741.JAFS01000001_gene1408 1.3e-90 275.0 COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia 74201|Verrucomicrobia GK PFAM ROK family protein - - - - - - - - - - - - ROK k141_14069_1 935836.JAEL01000034_gene4440 0.00015 49.7 COG1011@1|root,COG1011@2|Bacteria,1TRP5@1239|Firmicutes,4HBSP@91061|Bacilli,1ZDNA@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_14069_2 1469245.JFBG01000023_gene1223 6.45e-36 126.0 COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the bacterial histone-like protein family VL23_14575 - - - - - - - - - - - Bac_DNA_binding k141_14069_3 1279038.KB907342_gene2611 4.6e-27 103.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2UFDN@28211|Alphaproteobacteria,2JTWK@204441|Rhodospirillales 204441|Rhodospirillales P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - - - - - - - - - - Rieske k141_14069_4 1122201.AUAZ01000014_gene238 0.000163 47.4 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,467NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T SH3 domain protein ygiM GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - ko:K07184 - - - - ko00000 - - - SH3_3 k141_3615_1 1042375.AFPL01000044_gene1270 2.35e-25 102.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,46867@72275|Alteromonadaceae 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_3615_2 187272.Mlg_2440 3e-125 379.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales 135613|Chromatiales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_16848_1 1278309.KB907107_gene1742 2.58e-97 296.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XIAN@135619|Oceanospirillales 135619|Oceanospirillales N Belongs to the bacterial flagellin family flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_16848_2 1122599.AUGR01000007_gene1199 1.57e-201 588.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XIBV@135619|Oceanospirillales 135619|Oceanospirillales N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_21088_1 319224.Sputcn32_1042 7.08e-101 313.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,2QB0M@267890|Shewanellaceae 1236|Gammaproteobacteria P PFAM Sulfate transporter antisigma-factor antagonist STAS ychM GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - iSbBS512_1146.SbBS512_E1370 STAS,Sulfate_transp k141_21088_2 1278309.KB907104_gene875 1.81e-316 863.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XHE1@135619|Oceanospirillales 135619|Oceanospirillales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_21088_3 1278309.KB907104_gene874 8.06e-82 244.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1XJRY@135619|Oceanospirillales 135619|Oceanospirillales J Binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_21088_5 1278309.KB907104_gene872 1.23e-75 229.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1XK6B@135619|Oceanospirillales 135619|Oceanospirillales J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_21088_7 1278309.KB907104_gene870 3.99e-85 259.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,1XIFB@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_18243_1 1278309.KB907100_gene2000 2.52e-281 771.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1XI7B@135619|Oceanospirillales 135619|Oceanospirillales C Malate dehydrogenase maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_18243_3 1278309.KB907100_gene2002 0.0 1292.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XHF9@135619|Oceanospirillales 135619|Oceanospirillales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_18243_4 1278309.KB907100_gene2003 2.3e-78 248.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XIJZ@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_5724_1 1288826.MSNKSG1_00101 5.36e-88 265.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_5724_2 1288826.MSNKSG1_00096 3.08e-105 303.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S76U@1236|Gammaproteobacteria,46DNR@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ k141_5724_3 1288826.MSNKSG1_00086 2.29e-196 546.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,463Z3@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_5724_4 1288826.MSNKSG1_00081 0.0 1031.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,465I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M (Lipo)protein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_12672_2 323850.Shew_0528 8.42e-09 58.2 COG0790@1|root,COG0790@2|Bacteria,1NNDJ@1224|Proteobacteria,1SH6P@1236|Gammaproteobacteria,2QBFR@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM Sel1 domain protein repeat-containing protein - - - - - - - - - - - - Sel1 k141_2906_1 1288826.MSNKSG1_15646 0.0 1077.0 COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,1T3BE@1236|Gammaproteobacteria,46D4Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_2906_2 1288826.MSNKSG1_15651 6.67e-174 486.0 COG0834@1|root,COG0834@2|Bacteria,1RJ5A@1224|Proteobacteria,1S6WZ@1236|Gammaproteobacteria,46B7A@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - - - - - - - - - - SBP_bac_3 k141_21699_2 1387197.AWGA01000010_gene509 1.21e-11 59.3 2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,1S8U2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - k141_20372_1 314345.SPV1_05208 5.68e-29 121.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg k141_2205_1 292415.Tbd_0234 1.03e-66 229.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1KRGX@119069|Hydrogenophilales 119069|Hydrogenophilales E B12 binding domain - - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_10584_1 1317124.DW2_02779 7.03e-102 306.0 COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,2TUCZ@28211|Alphaproteobacteria,2XMR8@285107|Thioclava 28211|Alphaproteobacteria G Sugar ABC transporter substrate-binding protein MA20_37650 - - ko:K17315 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - SBP_bac_1,SBP_bac_8 k141_9159_2 765913.ThidrDRAFT_3852 6.18e-33 119.0 COG2940@1|root,COG2940@2|Bacteria,1RH54@1224|Proteobacteria 1224|Proteobacteria S SET domain - - - - - - - - - - - - SET k141_4298_1 519989.ECTPHS_12363 6.3e-148 433.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales 135613|Chromatiales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_15490_1 631362.Thi970DRAFT_04753 2.04e-106 326.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales 135613|Chromatiales U sulphate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_6386_1 760192.Halhy_1937 2.74e-66 217.0 COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes 976|Bacteroidetes IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_21089_1 857087.Metme_1082 1.62e-18 85.5 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1XGC2@135618|Methylococcales 135618|Methylococcales T HDOD domain - - - - - - - - - - - - HDOD k141_817_2 1288826.MSNKSG1_01808 3.15e-172 481.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,465GS@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_817_3 1288826.MSNKSG1_01803 8.39e-117 336.0 COG2340@1|root,COG2340@2|Bacteria,1PEEH@1224|Proteobacteria,1TA8R@1236|Gammaproteobacteria,46BPA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP k141_817_4 1288826.MSNKSG1_01798 2.12e-171 479.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria 1236|Gammaproteobacteria F glutamine amidotransferase guaA_2 - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k141_817_5 1288826.MSNKSG1_01793 8.12e-78 231.0 COG1716@1|root,COG1716@2|Bacteria,1PEEJ@1224|Proteobacteria,1S9J0@1236|Gammaproteobacteria,468T1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_817_6 1288826.MSNKSG1_01788 6.47e-164 460.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1SC6K@1236|Gammaproteobacteria,467NF@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0631 Serine threonine protein phosphatase - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_817_7 1288826.MSNKSG1_01783 0.0 981.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,465TI@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT COG0515 Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_234_1 1122134.KB893650_gene562 3.12e-16 81.6 2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria,1XQ67@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7211_1 1298867.AUES01000051_gene4504 2.31e-183 531.0 COG0653@1|root,COG0653@2|Bacteria,1MX0P@1224|Proteobacteria,2U086@28211|Alphaproteobacteria,3K2HA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U SecA preprotein cross-linking domain - - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind k141_7211_2 323848.Nmul_A0923 4.17e-20 92.0 COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2VSG3@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_16981_1 404380.Gbem_0781 4.81e-129 375.0 COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2WJGY@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM Iron-containing alcohol dehydrogenase bdhA - 1.1.1.1 ko:K00001,ko:K08325 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R02528,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC00739,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_19752_1 491952.Mar181_3433 2.23e-09 57.8 COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XI1G@135619|Oceanospirillales 135619|Oceanospirillales G Sugar ABC transporter substrate-binding protein gtsA - - ko:K17315 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - SBP_bac_1,SBP_bac_8 k141_19752_2 349521.HCH_06081 7.19e-102 304.0 COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,1S0D0@1236|Gammaproteobacteria,1XIUX@135619|Oceanospirillales 135619|Oceanospirillales P PFAM binding-protein-dependent transport systems inner membrane component gtsB - - ko:K17316 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_937_2 1123399.AQVE01000030_gene1374 3.17e-40 147.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Hydroxypyruvate reductase ttuD - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_9272_1 1278309.KB907101_gene739 4.45e-130 392.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1XH5W@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_9272_2 349521.HCH_02122 3.9e-20 87.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1XHER@135619|Oceanospirillales 135619|Oceanospirillales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_3053_1 1116472.MGMO_143c00070 1.39e-17 79.3 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1XFAR@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_3053_2 243365.CV_0776 5.16e-121 357.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,2KPVK@206351|Neisseriales 206351|Neisseriales H Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH k141_21873_1 471854.Dfer_4353 9.38e-48 154.0 COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,47PQH@768503|Cytophagia 976|Bacteroidetes J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 k141_21873_2 1089547.KB913013_gene2127 1.38e-40 135.0 COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,47R6N@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_20512_1 977880.RALTA_B0100 0.000419 49.7 COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - CHASE,EAL,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg k141_18381_3 314287.GB2207_05102 4.68e-16 76.3 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,1J7VB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase dam GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k141_4467_1 243233.MCA2967 1.08e-41 149.0 COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1XECH@135618|Methylococcales 135618|Methylococcales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_938_1 269799.Gmet_0007 4.85e-92 281.0 COG2801@1|root,COG2801@2|Bacteria,1NUYG@1224|Proteobacteria,42ZK0@68525|delta/epsilon subdivisions,2WUUJ@28221|Deltaproteobacteria,43URT@69541|Desulfuromonadales 28221|Deltaproteobacteria L Homeodomain-like domain - - - - - - - - - - - - HTH_23,rve k141_19753_1 314271.RB2654_16321 4.4e-85 268.0 COG1010@1|root,COG2073@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,1MU79@1224|Proteobacteria,2TQJQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H precorrin-3b cobJ - 2.1.1.131,3.7.1.12 ko:K05934,ko:K13541 ko00860,ko01100,map00860,map01100 - R05180,R05809,R07772 RC00003,RC01293,RC01545,RC02097,RC03471 ko00000,ko00001,ko01000 - - - CbiG_C,CbiG_N,TP_methylase k141_9273_1 391038.Bphy_2479 2.98e-34 125.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,1K657@119060|Burkholderiaceae 28216|Betaproteobacteria M Nucleotidyl transferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_21874_1 1123368.AUIS01000032_gene1394 1.26e-65 216.0 COG1080@1|root,COG1080@2|Bacteria 2|Bacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_9961_1 1461693.ATO10_09013 2.36e-109 330.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria 28211|Alphaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_939_1 2340.JV46_03220 7.78e-89 273.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1J6QH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T HPP family - - - ko:K07168 - - - - ko00000 - - - HPP k141_5114_1 1122599.AUGR01000007_gene1115 2.05e-07 52.4 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XNKM@135619|Oceanospirillales 135619|Oceanospirillales C Nitrite and sulphite reductase 4Fe-4S domain - - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_5114_2 1122599.AUGR01000007_gene1114 3.03e-58 186.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria,1XKEY@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF934 k141_9274_1 1042375.AFPL01000022_gene2660 2.88e-103 303.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,466DA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_238_1 371731.Rsw2DRAFT_0599 1.18e-78 242.0 COG5010@1|root,COG5010@2|Bacteria,1QYC3@1224|Proteobacteria,2TXN6@28211|Alphaproteobacteria,1FBJB@1060|Rhodobacter 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19 k141_9962_1 314292.VAS14_02993 2.62e-17 78.2 COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,1XSCJ@135623|Vibrionales 135623|Vibrionales J translation elongation factor activity yeiP GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_9962_2 1380380.JIAX01000010_gene44 1.01e-19 90.5 COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2TU4M@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_17690_1 1288826.MSNKSG1_18070 6.06e-33 121.0 COG3025@1|root,COG3025@2|Bacteria,1MY43@1224|Proteobacteria,1RMP4@1236|Gammaproteobacteria,463Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Adenylate cyclase ygiF - 3.6.1.25 ko:K18446 - - - - ko00000,ko01000 - - - CHAD,CYTH k141_17690_2 1288826.MSNKSG1_18065 6.49e-213 590.0 COG3203@1|root,COG3203@2|Bacteria,1N04Q@1224|Proteobacteria 1224|Proteobacteria M PFAM porin Gram-negative type - - - ko:K08720,ko:K09476 ko01501,ko02020,ko05111,map01501,map02020,map05111 M00746 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.1.1.1,1.B.1.2.1 - - Porin_4 k141_17690_3 1288826.MSNKSG1_18060 2.75e-212 590.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,466WT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_1660_1 1479237.JMLY01000001_gene1410 4.61e-218 611.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,464S8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280 Aldedh k141_1660_2 519989.ECTPHS_03016 2.85e-58 187.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales 135613|Chromatiales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_3752_1 1163617.SCD_n00030 3.3e-210 600.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria 28216|Betaproteobacteria NU type II secretion system protein E gspE1 - - ko:K02454,ko:K02652,ko:K12276 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_239_1 857087.Metme_4529 4.18e-153 466.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XE0B@135618|Methylococcales 135618|Methylococcales H Vitamin B12 dependent methionine synthase, activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_2295_1 1288826.MSNKSG1_05041 2.88e-127 370.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,464JF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006633,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008776,GO:0008980,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019541,GO:0019542,GO:0019665,GO:0019666,GO:0019752,GO:0032787,GO:0042710,GO:0043167,GO:0043169,GO:0043436,GO:0044010,GO:0044011,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046394,GO:0046395,GO:0046459,GO:0046872,GO:0046914,GO:0051703,GO:0051704,GO:0051790,GO:0055114,GO:0071704,GO:0072330,GO:0090605,GO:0090609,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.7.2.1,2.7.2.15 ko:K00925,ko:K00932 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3309,iECS88_1305.ECS88_3508,iEcSMS35_1347.EcSMS35_3411,iLF82_1304.LF82_2233,iSDY_1059.SDY_2492,iUTI89_1310.UTI89_C3550,iYL1228.KPN_02687 Acetate_kinase k141_2295_2 1288826.MSNKSG1_05036 0.0 1349.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,464SE@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the CobB CobQ family pta GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - iG2583_1286.G2583_2834,iYL1228.KPN_02688 AAA_26,DRTGG,PTA_PTB k141_2295_3 1288826.MSNKSG1_05031 0.0 879.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,464AT@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_2295_4 1288826.MSNKSG1_05026 1.05e-187 532.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,4648Z@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_2295_5 1288826.MSNKSG1_05021 6.88e-149 419.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,467Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_2295_6 1288826.MSNKSG1_05016 2.15e-293 802.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,464GH@72275|Alteromonadaceae 1236|Gammaproteobacteria J histidyl-tRNA synthetase hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358 HGTP_anticodon,tRNA-synt_His k141_2295_7 1288826.MSNKSG1_05011 3.27e-127 369.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,464MT@72275|Alteromonadaceae 1236|Gammaproteobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 GcpE k141_7212_1 1288826.MSNKSG1_05601 1.3e-210 603.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,469QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_7212_2 1288826.MSNKSG1_05596 0.0 886.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,469HG@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_21875_1 66897.DJ64_24540 3.31e-06 50.8 COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria 201174|Actinobacteria P phosphate binding protein pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - HSP70,PBP_like,PBP_like_2 k141_21875_2 413404.Rmag_0825 1.11e-80 245.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria,1J6FB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Nitroreductase family ycdI - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k141_1661_1 1249627.D779_1731 2.27e-96 296.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_240_1 398580.Dshi_2186 3.83e-63 194.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_9963_1 626887.J057_10736 4.33e-14 80.5 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_21876_1 1049564.TevJSym_am00160 4.74e-64 216.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,1J9QI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_19754_1 857087.Metme_4125 3.13e-123 367.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales 135618|Methylococcales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_942_1 342610.Patl_0345 2.32e-54 178.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,2Q193@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phospholipase/Carboxylesterase estB - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_16244_1 485916.Dtox_0078 5.4e-09 58.5 COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,2612H@186807|Peptococcaceae 186801|Clostridia H Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source cbiA - 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 - - - AAA_26,CbiA,GATase_3 k141_16244_2 1123401.JHYQ01000003_gene2058 7.24e-27 102.0 COG0316@1|root,COG0316@2|Bacteria,1N8ZN@1224|Proteobacteria,1T0Z0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn k141_5115_1 1034943.BN1094_03531 1.81e-44 166.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1JCHF@118969|Legionellales 118969|Legionellales S Alpha-2-macroglobulin family - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1 k141_11425_1 1288826.MSNKSG1_06943 1.51e-83 263.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,469ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k141_11425_2 1288826.MSNKSG1_06948 1.16e-242 666.0 COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,464GV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Lipopolysaccharide biosynthesis protein walW - - - - - - - - - - - - k141_20515_1 396588.Tgr7_1465 4.78e-31 114.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1SEBT@1236|Gammaproteobacteria,1WZ6I@135613|Chromatiales 135613|Chromatiales C TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_20515_2 1158146.KB907126_gene1548 0.00032 42.7 COG2142@1|root,COG2142@2|Bacteria,1RH1K@1224|Proteobacteria,1S7GT@1236|Gammaproteobacteria,1WYKS@135613|Chromatiales 135613|Chromatiales C Succinate dehydrogenase hydrophobic membrane anchor - - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_18382_1 1123393.KB891332_gene2696 9.43e-102 306.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,1KRH0@119069|Hydrogenophilales 119069|Hydrogenophilales I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_18382_2 1123399.AQVE01000006_gene3467 2.49e-89 273.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_9276_1 748247.AZKH_1566 1.84e-78 243.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,2WGG5@28216|Betaproteobacteria,2KZPF@206389|Rhodocyclales 206389|Rhodocyclales E AAA domain, putative AbiEii toxin, Type IV TA system - - 3.6.3.21 ko:K10017,ko:K10025 ko02010,map02010 M00225,M00226,M00235 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.1,3.A.1.3.11 - - ABC_tran k141_21209_1 1232410.KI421428_gene1061 2.9e-09 62.8 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,43TQK@69541|Desulfuromonadales 28221|Deltaproteobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB-2 - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_21209_2 580332.Slit_2852 3.44e-41 139.0 COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,2VWEE@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_21209_3 472759.Nhal_3058 6.83e-114 329.0 COG0288@1|root,COG0288@2|Bacteria,1R3SC@1224|Proteobacteria,1RRB4@1236|Gammaproteobacteria,1WXB8@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_21209_4 314275.MADE_1007645 3.58e-68 216.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,464HV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_14905_1 930169.B5T_03109 3.13e-136 395.0 COG1637@1|root,COG3586@1|root,COG1637@2|Bacteria,COG3586@2|Bacteria,1R4TU@1224|Proteobacteria,1RQ7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - - - - - - - - - - NucS k141_14905_3 998674.ATTE01000001_gene2527 5.17e-51 180.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,461QF@72273|Thiotrichales 72273|Thiotrichales L Type I restriction enzyme R protein N terminus (HSDR_N) - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - HSDR_N,ResIII k141_241_1 1122214.AQWH01000002_gene4300 3.01e-48 163.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2TT7X@28211|Alphaproteobacteria,2PKDA@255475|Aurantimonadaceae 28211|Alphaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family eutC - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_241_2 1287276.X752_10620 3.34e-36 132.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,43GQB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Ectoine utilization eutB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_21877_1 1207063.P24_06586 2.56e-20 89.7 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2JPCN@204441|Rhodospirillales 204441|Rhodospirillales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_21877_2 1122137.AQXF01000007_gene3534 9.28e-42 142.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_16983_1 880072.Desac_1129 8.38e-91 279.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MRE2@213462|Syntrophobacterales 28221|Deltaproteobacteria KT PFAM Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,PAS_9,Sigma54_activat k141_17692_1 396588.Tgr7_0817 6.4e-201 581.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales 135613|Chromatiales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_9964_1 90814.KL370891_gene1377 5.15e-131 384.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2,Usp k141_2298_1 1337093.MBE-LCI_2938 4.9e-27 105.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,2P8XS@245186|Loktanella 28211|Alphaproteobacteria G HpcH/HpaI aldolase/citrate lyase family hpaI GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0008150,GO:0008152,GO:0016829,GO:0016830,GO:0016832,GO:0044238,GO:0044424,GO:0044464,GO:0071704 4.1.2.20,4.1.2.52 ko:K01630,ko:K02510 ko00053,ko00350,ko01120,map00053,map00350,map01120 - R01645,R01647,R02754,R03277 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_2298_2 388401.RB2150_12856 1.73e-57 181.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,3ZHPE@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_7214_1 1304888.ATWF01000001_gene1255 3.52e-26 114.0 COG5002@1|root,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - - - - - - - - - - AAA_16,CHASE,GAF,HAMP,HATPase_c,HisKA,Hpt,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Pkinase,Response_reg,dCache_1 k141_5840_22 220341.16506051 2.03e-49 180.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1S8D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k141_5840_25 1444711.CCJF01000005_gene419 0.000717 44.7 2E5FX@1|root,3307M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_5840_32 375286.mma_2211 4.65e-102 300.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k141_5932_2 1082931.KKY_935 5.6e-82 259.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,3N9DI@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P Major Facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 k141_1052_1 1278309.KB907102_gene272 0.0 912.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,1XHHU@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_1052_2 1278309.KB907102_gene270 1.26e-60 187.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,1XKFT@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the BolA IbaG family bolA - - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_1052_3 1278309.KB907102_gene269 6.78e-182 516.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,1RR20@1236|Gammaproteobacteria,1XHNB@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 k141_8095_1 1288826.MSNKSG1_04221 4.03e-101 303.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,465C7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_16342_1 1121127.JAFA01000036_gene3585 4.39e-49 181.0 COG0501@1|root,COG0501@2|Bacteria,1R7VU@1224|Proteobacteria,2VKS8@28216|Betaproteobacteria 28216|Betaproteobacteria O peptidase m48, ste24p - - - - - - - - - - - - Peptidase_M48 k141_3836_1 443152.MDG893_03905 4.09e-64 206.0 COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,1SVEG@1236|Gammaproteobacteria,46BGR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_18460_1 1288826.MSNKSG1_02148 6.65e-37 135.0 COG0477@1|root,COG2814@2|Bacteria,1R3RZ@1224|Proteobacteria,1S072@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_18460_2 1288826.MSNKSG1_02153 1.71e-163 459.0 2F9BN@1|root,341NM@2|Bacteria,1NYWS@1224|Proteobacteria,1SQE6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP k141_18460_3 1288826.MSNKSG1_02158 3.15e-180 509.0 COG1397@1|root,COG1397@2|Bacteria,1RINX@1224|Proteobacteria,1SPBF@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH k141_12923_1 207954.MED92_07936 1.82e-18 84.3 COG0304@1|root,COG0304@2|Bacteria,1MV67@1224|Proteobacteria,1RMXJ@1236|Gammaproteobacteria,1XHM8@135619|Oceanospirillales 135619|Oceanospirillales IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.180 ko:K18473 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_12923_3 1278309.KB907100_gene1832 2.44e-87 264.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1XJJZ@135619|Oceanospirillales 135619|Oceanospirillales L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_10091_1 1288826.MSNKSG1_08823 1.23e-96 285.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,46612@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313 Inositol_P k141_10091_2 443152.MDG893_01275 4.76e-85 253.0 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,468F4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0250 Transcription antiterminator rfaH GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_15709_3 391615.ABSJ01000034_gene1047 1.64e-24 100.0 COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6- deoxy-6-sulfo-D-fructose 1-phosphate (SFP) yihV GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0061594,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 2.7.1.184,2.7.1.3 ko:K00846,ko:K18478 ko00051,ko01100,ko01120,map00051,map01100,map01120 - R00866,R03819,R10970 RC00002,RC00017,RC00608 ko00000,ko00001,ko01000,ko04147 - - - PfkB,Rieske k141_1770_1 1288826.MSNKSG1_01933 2.18e-222 615.0 COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,1SYJD@1236|Gammaproteobacteria,46A2Z@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_1770_2 1288826.MSNKSG1_01928 7.39e-196 545.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,1SYK4@1236|Gammaproteobacteria,46AGZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_1770_3 1288826.MSNKSG1_01923 8.94e-272 746.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RY3R@1236|Gammaproteobacteria,469EU@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_1770_4 1288826.MSNKSG1_01918 5.65e-168 469.0 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,1RQZM@1236|Gammaproteobacteria,46A98@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_1770_5 1288826.MSNKSG1_01913 4.86e-71 220.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,469DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component braF-2 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_13587_2 676032.FN3523_0092 1.92e-109 326.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,45ZSN@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_20614_1 1208323.B30_15416 2.68e-05 43.1 2DS69@1|root,33ERA@2|Bacteria 2|Bacteria S Entericidin EcnA/B family - - - - - - - - - - - - Entericidin k141_20614_2 1469613.JT55_12615 5.56e-123 367.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,3FCGZ@34008|Rhodovulum 28211|Alphaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_17799_2 455436.DS989810_gene234 2.72e-19 83.6 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,467BX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_1053_1 1288494.EBAPG3_13560 1.3e-08 63.2 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,371WM@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function - - - - - - - - - - - - AsmA_2,DUF3971 k141_19222_2 614083.AWQR01000028_gene3128 7.33e-61 225.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VMCI@28216|Betaproteobacteria 28216|Betaproteobacteria T GAF domain - - - - - - - - - - - - EAL,GAF,GGDEF,PAS_4,PAS_8,PAS_9 k141_14976_1 1288826.MSNKSG1_07743 1.1e-120 364.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,464G0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009436,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iJN746.PP_0356,iWFL_1372.ECW_m3242 Malate_synthase k141_14976_2 1288826.MSNKSG1_07738 2.3e-194 540.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,4649I@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_0281 THF_DHG_CYH,THF_DHG_CYH_C k141_14976_3 1288826.MSNKSG1_07733 4.15e-295 807.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,46543@72275|Alteromonadaceae 1236|Gammaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_13616_2 519989.ECTPHS_04074 9.13e-61 196.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales 135613|Chromatiales H Belongs to the ribF family - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_3843_1 105559.Nwat_0980 6.6e-153 458.0 COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim k141_1074_1 395493.BegalDRAFT_0232 1.39e-142 417.0 COG4651@1|root,COG4651@2|Bacteria,1QUQS@1224|Proteobacteria,1T21E@1236|Gammaproteobacteria,461MK@72273|Thiotrichales 72273|Thiotrichales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_1074_2 1336233.JAEH01000001_gene713 3.54e-10 63.2 COG2199@1|root,COG3706@2|Bacteria,1RBKK@1224|Proteobacteria,1S2QB@1236|Gammaproteobacteria,2QBHA@267890|Shewanellaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_7339_2 1123377.AUIV01000024_gene121 3.57e-13 65.9 COG3831@1|root,COG3831@2|Bacteria,1NGUF@1224|Proteobacteria,1T9BG@1236|Gammaproteobacteria,1X84E@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - WGR k141_7339_3 519989.ECTPHS_11822 2.7e-170 488.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X0VD@135613|Chromatiales 135613|Chromatiales F Belongs to the dGTPase family. Type 2 subfamily - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_7339_4 765912.Thimo_0089 2.75e-136 396.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_12947_1 626887.J057_03825 7.6e-84 256.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,4672Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase (AAA superfamily) - - - ko:K06923 - - - - ko00000 - - - DUF815 k141_383_1 631362.Thi970DRAFT_01933 5.79e-122 355.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales 135613|Chromatiales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_1788_2 870967.VIS19158_00830 2.16e-43 148.0 2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,1S83N@1236|Gammaproteobacteria,1XWXW@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2846) - - - - - - - - - - - - DUF2846 k141_2450_1 631362.Thi970DRAFT_04697 6.17e-63 218.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_15730_1 666509.RCA23_c12090 6.17e-141 402.0 COG2207@1|root,COG2207@2|Bacteria,1MUV5@1224|Proteobacteria,2TS27@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional - - - - - - - - - - - - AraC_binding,HTH_18 k141_14993_1 754477.Q7C_1200 7.28e-25 103.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales 72273|Thiotrichales CP Proton-translocating NADH-quinone oxidoreductase, chain L - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_14993_2 2340.JV46_20400 2.58e-118 354.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1J5MF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NADH ubiquinone oxidoreductase subunit nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_3844_1 765913.ThidrDRAFT_3349 2.03e-23 94.7 28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria,1WY0Y@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_3844_2 1121939.L861_14540 2.27e-16 78.6 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,1XKW7@135619|Oceanospirillales 135619|Oceanospirillales S PKHD-type hydroxylase - - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 k141_1789_1 1411685.U062_00464 6.33e-07 56.2 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1J577@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 k141_384_1 95619.PM1_0209120 4e-54 184.0 COG0642@1|root,COG0642@2|Bacteria,1MURQ@1224|Proteobacteria,1RP9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase fleS - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8 k141_1075_1 1122599.AUGR01000012_gene834 2.75e-123 367.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1XIRA@135619|Oceanospirillales 135619|Oceanospirillales EGP MFS transporter permease - - - - - - - - - - - - MFS_1 k141_12252_1 765914.ThisiDRAFT_2507 5.42e-86 262.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales 135613|Chromatiales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_12252_2 522306.CAP2UW1_3782 3.88e-26 101.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,1KQ34@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria U Preprotein translocase subunit SecG secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_10861_1 491952.Mar181_1480 1.02e-107 337.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHS3@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,dCache_2 k141_14994_1 1250232.JQNJ01000001_gene1739 5.83e-12 67.0 COG1361@1|root,COG3209@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes 976|Bacteroidetes M SPTR CHU large protein - - - - - - - - - - - - CHU_C,DUF11,SprB k141_14994_2 643867.Ftrac_0360 4.2e-24 100.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF k141_2451_1 981085.XP_010109403.1 3.21e-36 122.0 2D40V@1|root,2STG3@2759|Eukaryota,381GS@33090|Viridiplantae,3GMA3@35493|Streptophyta,4JUQW@91835|fabids 35493|Streptophyta - - - - - - - - - - - - - - - k141_1076_1 1122137.AQXF01000005_gene1320 5.04e-77 234.0 COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6ZM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 k141_12949_1 314345.SPV1_06144 5.48e-08 53.1 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria 1224|Proteobacteria E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_12949_2 314345.SPV1_06149 8e-117 340.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria 1224|Proteobacteria F Creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_7340_1 545276.KB898724_gene1865 1.22e-177 521.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_3845_1 1026882.MAMP_01841 2.37e-07 54.7 2A495@1|root,30SUK@2|Bacteria,1PJZN@1224|Proteobacteria,1SX6T@1236|Gammaproteobacteria,46387@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_4571_1 1385517.N800_08200 5.59e-13 76.6 COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T49N@1236|Gammaproteobacteria,1XD92@135614|Xanthomonadales 135614|Xanthomonadales NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_385_1 857087.Metme_0214 2.68e-83 261.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XDYK@135618|Methylococcales 135618|Methylococcales F Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k141_16360_1 1288826.MSNKSG1_04326 1.77e-232 646.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,465B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DEAD box helicase family dbpA GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_16360_2 1288826.MSNKSG1_04331 7.77e-45 145.0 COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SGS8@1236|Gammaproteobacteria,46917@72275|Alteromonadaceae 1236|Gammaproteobacteria C Lyase and sodium transporter oadG GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma k141_16360_3 1288826.MSNKSG1_04336 0.0 1101.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,4659U@72275|Alteromonadaceae 1236|Gammaproteobacteria CI COG5016 Pyruvate oxaloacetate carboxyltransferase oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_16360_4 1288826.MSNKSG1_04341 7.82e-297 812.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,464KB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit oadB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008948,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044464,GO:0055114,GO:0071944 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta k141_6601_1 555778.Hneap_2070 2.84e-66 218.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_6601_2 713586.KB900536_gene2174 3.18e-114 356.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1RQY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07710 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_8111_1 1177154.Y5S_02582 8.49e-09 67.8 COG3266@1|root,COG5492@1|root,COG3266@2|Bacteria,COG5492@2|Bacteria,1R8Z4@1224|Proteobacteria,1S0IR@1236|Gammaproteobacteria,1XMN8@135619|Oceanospirillales 135619|Oceanospirillales N Protein of unknown function (DUF1566) - - - - - - - - - - - - DUF1566 k141_12950_1 754476.Q7A_1472 1.49e-112 333.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales 72273|Thiotrichales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_5247_1 1042375.AFPL01000032_gene1019 4.37e-164 472.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RP59@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_5247_2 1042375.AFPL01000032_gene1020 4.87e-185 531.0 COG1251@1|root,COG1773@1|root,COG1251@2|Bacteria,COG1773@2|Bacteria,1MW58@1224|Proteobacteria,1T1NU@1236|Gammaproteobacteria,46DBH@72275|Alteromonadaceae 1236|Gammaproteobacteria C Rubredoxin rubB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0015046,GO:0016491,GO:0016730,GO:0016731,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.18.1.1 ko:K05297,ko:K12265 ko00071,ko05132,map00071,map05132 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_15733_1 1124983.PFLCHA0_c06830 2.98e-58 186.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1YPGV@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0560 DHquinase_II k141_15733_2 545276.KB898725_gene869 6.89e-07 50.1 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1WYFK@135613|Chromatiales 135613|Chromatiales CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,Redoxin k141_14996_1 530564.Psta_3309 9.94e-19 91.3 COG0661@1|root,COG0661@2|Bacteria 2|Bacteria I Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis - - - - - - - - - - - - ABC1 k141_11536_1 1288826.MSNKSG1_02981 3.93e-209 580.0 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,466GQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG4240 Predicted kinase - - 2.7.1.31 ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ArgK,PRK k141_11536_2 1288826.MSNKSG1_02976 0.0 974.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_1079_1 985255.APHJ01000054_gene2032 1.41e-17 89.0 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,4NKIP@976|Bacteroidetes,1I0IX@117743|Flavobacteriia,2P6AJ@244698|Gillisia 976|Bacteroidetes M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - DUF4394,Gal_Lectin k141_5248_1 1530186.JQEY01000001_gene1089 9.17e-62 204.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2TQJY@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Hydroxypyruvate reductase ttuD - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_15734_1 1288963.ADIS_1679 6.98e-53 174.0 COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,47P6X@768503|Cytophagia 976|Bacteroidetes F uracil phosphoribosyltransferase upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase k141_5409_1 1288826.MSNKSG1_13937 9.44e-222 616.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,469PM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_5409_2 1288826.MSNKSG1_13932 3.58e-209 587.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_4717_1 1288826.MSNKSG1_15906 6.55e-193 543.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM k141_4717_2 1288826.MSNKSG1_15911 5.21e-124 353.0 COG4665@1|root,COG4665@2|Bacteria,1RE14@1224|Proteobacteria,1S582@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - - - - - - - - - - DctQ k141_4717_3 1288826.MSNKSG1_15916 2.64e-243 669.0 COG1638@1|root,COG1638@2|Bacteria,1R7GB@1224|Proteobacteria,1RYMY@1236|Gammaproteobacteria,46CNZ@72275|Alteromonadaceae 1236|Gammaproteobacteria G transport system, periplasmic component - - - - - - - - - - - - DctP k141_4717_4 1288826.MSNKSG1_15921 5.32e-160 450.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1SF7D@1236|Gammaproteobacteria,46CP6@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_4717_5 1288826.MSNKSG1_15926 0.0 1037.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RPG7@1236|Gammaproteobacteria,466C3@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_4717_6 1288826.MSNKSG1_15931 2.78e-180 503.0 COG1028@1|root,COG1028@2|Bacteria,1MU3W@1224|Proteobacteria,1RQ6H@1236|Gammaproteobacteria,467MK@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_4717_7 1288826.MSNKSG1_15936 5.17e-102 295.0 COG2050@1|root,COG2050@2|Bacteria,1MZB4@1224|Proteobacteria,1SBIC@1236|Gammaproteobacteria,46BU0@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT k141_4717_8 1288826.MSNKSG1_15941 2.19e-291 795.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,46475@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_9485_2 616991.JPOO01000001_gene4488 2.7e-18 77.8 2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_6706_1 1123237.Salmuc_04796 1.72e-84 254.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_17,Fer4_8 k141_6040_1 1288826.MSNKSG1_04716 4.66e-120 365.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,464NY@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_22099_1 1163408.UU9_01749 1.28e-17 81.3 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X6S4@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis signal transduction protein - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_22099_2 998674.ATTE01000001_gene3592 3.84e-28 110.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,460NP@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_1237_1 1100720.ALKN01000049_gene533 2.55e-11 65.9 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VP2F@28216|Betaproteobacteria,4AJA7@80864|Comamonadaceae 28216|Betaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_15115_1 1121271.AUCM01000005_gene763 1e-43 150.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.1.77 ko:K01459 - - - - ko00000,ko01000 - - - CN_hydrolase k141_21448_1 1123392.AQWL01000007_gene984 1.02e-177 508.0 COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,2VJFD@28216|Betaproteobacteria,1KRCB@119069|Hydrogenophilales 119069|Hydrogenophilales P FAD-binding domain - - - - - - - - - - - - FAD_binding_8,Ferric_reduct k141_21448_2 1479237.JMLY01000001_gene3658 4.24e-101 297.0 COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,1RPXN@1236|Gammaproteobacteria,4682Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K MAATS-type transcriptional repressor, C-terminal region acrR - - ko:K03577,ko:K18135 ko01501,map01501 M00647 - - ko00000,ko00001,ko00002,ko03000 - - - TetR_C_2,TetR_N k141_14376_1 1278309.KB907099_gene2656 7.13e-99 305.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,1XH3C@135619|Oceanospirillales 135619|Oceanospirillales KQ transcriptional regulator - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_1908_1 207954.MED92_15048 6.79e-77 235.0 COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,1S44W@1236|Gammaproteobacteria,1XK8V@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_3318_1 2340.JV46_12910 3.15e-259 726.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1J5CY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA2 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_3318_2 1123393.KB891326_gene83 8.6e-64 211.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1KSJ5@119069|Hydrogenophilales 119069|Hydrogenophilales L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_thumb,HHH_5,HHH_8 k141_17971_1 666685.R2APBS1_3545 9.37e-48 173.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1X5HN@135614|Xanthomonadales 135614|Xanthomonadales L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N,SWIM k141_12402_1 768066.HELO_2139 2.03e-06 50.1 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transport system permease component ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_12402_2 765914.ThisiDRAFT_2535 3.72e-64 204.0 COG1136@1|root,COG1136@2|Bacteria,1RH0D@1224|Proteobacteria,1T21A@1236|Gammaproteobacteria,1X2P3@135613|Chromatiales 135613|Chromatiales V pfam abc - - - - - - - - - - - - ABC_tran k141_10983_1 765914.ThisiDRAFT_0138 2.89e-13 72.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT CheW domain protein VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_10983_2 555778.Hneap_0722 3.96e-101 303.0 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1WXRP@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_13772_1 1288826.MSNKSG1_16486 3.66e-231 637.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,1RMCE@1236|Gammaproteobacteria,465D0@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yhbW - - - - - - - - - - - Bac_luciferase k141_13772_2 1288826.MSNKSG1_16491 5.1e-151 424.0 COG2129@1|root,COG2129@2|Bacteria,1RFU9@1224|Proteobacteria,1S4S2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterases, related to the Icc protein - - - - - - - - - - - - Metallophos,Metallophos_2 k141_13772_3 1288826.MSNKSG1_16496 1.96e-61 195.0 28IWY@1|root,2Z8V1@2|Bacteria,1R9PZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_5410_1 402777.KB235903_gene1355 1.17e-14 79.3 COG0438@1|root,COG0438@2|Bacteria,1G1WK@1117|Cyanobacteria,1HBAI@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_524_1 1278309.KB907101_gene379 4.89e-09 60.8 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1XRT5@135619|Oceanospirillales 135619|Oceanospirillales T Histidine Phosphotransfer domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS_4,Response_reg k141_524_2 519989.ECTPHS_03262 1.13e-127 375.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria,1WX76@135613|Chromatiales 135613|Chromatiales E lysine 2,3-aminomutase - - - - - - - - - - - - - k141_1238_1 1120963.KB894503_gene1983 2.1e-97 302.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,2PZWR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_4718_1 1278309.KB907100_gene2265 3.12e-100 292.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XJV4@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) - - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_6041_1 1168067.JAGP01000001_gene196 4.2e-50 173.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,460GW@72273|Thiotrichales 72273|Thiotrichales J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD - 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_6041_2 395493.BegalDRAFT_1237 1.97e-32 117.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,4614W@72273|Thiotrichales 72273|Thiotrichales S PFAM Smr - - - - - - - - - - - - Smr k141_13773_1 1049564.TevJSym_aw00360 4.31e-46 154.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfur oxidation protein SoxY soxY - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_6707_1 313606.M23134_03423 3.16e-17 83.2 COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47MBB@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_6707_2 1319815.HMPREF0202_01436 1.03e-05 49.3 COG0859@1|root,COG0859@2|Bacteria,378KR@32066|Fusobacteria 32066|Fusobacteria M Heptosyltransferase II - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_10984_1 886379.AEWI01000023_gene80 1.42e-98 315.0 COG4772@1|root,COG4772@2|Bacteria,4PM03@976|Bacteroidetes,2G09Q@200643|Bacteroidia,3XIVZ@558415|Marinilabiliaceae 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_525_1 1288826.MSNKSG1_01858 1.76e-116 353.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,465CI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria vgrG GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564 - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_8225_1 83406.HDN1F_18490 4.82e-203 568.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1J4CN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_8225_2 1123401.JHYQ01000001_gene1911 2.08e-05 46.2 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,460KW@72273|Thiotrichales 72273|Thiotrichales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_17222_3 1121935.AQXX01000104_gene373 7.35e-32 111.0 2EA6R@1|root,30KMZ@2|Bacteria,1Q1AX@1224|Proteobacteria,1T8WJ@1236|Gammaproteobacteria,1XMUG@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3185) - - - - - - - - - - - - DUF3185 k141_13079_1 1288826.MSNKSG1_11248 2.46e-264 726.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4644H@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K01766,ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_13079_2 1288826.MSNKSG1_11253 3.02e-79 235.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,468EU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the HesB IscA family sufA - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_13079_3 1288826.MSNKSG1_11258 1.69e-128 365.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S4TX@1236|Gammaproteobacteria,466CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-sulfur cluster biosynthetic enzyme - - - - - - - - - - - - FeS_assembly_P k141_13079_4 1288826.MSNKSG1_11263 1.46e-104 302.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,467HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2166 SufE protein probably involved in Fe-S center assembly sufE - - ko:K02426 - - - - ko00000 - - - SufE k141_13079_5 1288826.MSNKSG1_11268 1.78e-249 688.0 28KVI@1|root,2ZAC4@2|Bacteria,1RBAQ@1224|Proteobacteria,1S3C3@1236|Gammaproteobacteria,4677V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flagellar assembly protein T, C-terminal domain flgT - - - - - - - - - - - FlgT_C,FlgT_M,FlgT_N k141_8810_1 1278309.KB907107_gene1733 6.31e-140 412.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XHPQ@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_8810_2 1278309.KB907107_gene1734 1.85e-291 800.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XINN@135619|Oceanospirillales 135619|Oceanospirillales T response regulator - - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_6042_1 748247.AZKH_3238 1.91e-16 75.1 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,2KX24@206389|Rhodocyclales 206389|Rhodocyclales K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_6042_2 1206726.BAFV01000039_gene2833 3.91e-06 48.5 COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria,4G0QC@85025|Nocardiaceae 201174|Actinobacteria O DSBA-like thioredoxin domain - - - - - - - - - - - - Thioredoxin_4 k141_22102_1 391603.FBALC1_04652 4.3e-23 102.0 COG2374@1|root,COG2866@1|root,COG4886@1|root,COG2374@2|Bacteria,COG2866@2|Bacteria,COG4886@2|Bacteria,4NF17@976|Bacteroidetes,1IJNI@117743|Flavobacteriia 976|Bacteroidetes O Mycoplasma protein of unknown function, DUF285 - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF285,LRR_5 k141_14377_1 1123368.AUIS01000031_gene1431 0.000398 43.1 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase pucG - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_14377_3 1123228.AUIH01000018_gene3520 7.36e-61 206.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1XH5W@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_10985_1 1121481.AUAS01000007_gene991 2.85e-58 198.0 COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,47JXP@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_5411_1 105425.BBPL01000002_gene6622 0.000248 46.6 COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,2NHBP@228398|Streptacidiphilus 201174|Actinobacteria S Transporter associated domain corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_5411_2 697282.Mettu_0680 4.17e-54 174.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XFBM@135618|Methylococcales 135618|Methylococcales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_5411_3 187272.Mlg_0395 2.98e-15 74.7 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1WW3U@135613|Chromatiales 135613|Chromatiales T PFAM PhoH family protein - - - ko:K06217 - - - - ko00000 - - - PhoH k141_9486_1 1101195.Meth11DRAFT_2036 4.46e-86 288.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1R1AH@1224|Proteobacteria,2WI0K@28216|Betaproteobacteria 28216|Betaproteobacteria KLT PFAM Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_21450_1 384765.SIAM614_11988 6.91e-26 110.0 COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily sam - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA k141_1911_1 697281.Mahau_0485 5.21e-12 71.2 COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,42FSR@68295|Thermoanaerobacterales 186801|Clostridia O Endopeptidase La - - 3.4.21.53 ko:K04076 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k141_3953_2 261292.Nit79A3_1273 4.38e-59 189.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales 28216|Betaproteobacteria CO oxidoreductase DsbE dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin k141_3953_3 270374.MELB17_17929 1.87e-11 64.3 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4649T@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1138 Cytochrome c biogenesis factor ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_13080_1 1178482.BJB45_00320 1.57e-59 191.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria,1XH8R@135619|Oceanospirillales 135619|Oceanospirillales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_13774_2 472759.Nhal_0861 2.75e-58 183.0 COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria,1X13M@135613|Chromatiales 135613|Chromatiales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_10253_2 56780.SYN_03249 1.88e-171 492.0 COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,42TEG@68525|delta/epsilon subdivisions,2WPXW@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Helix-turn-helix domain of transposase family ISL3 - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 k141_12404_1 1294143.H681_20200 8.42e-112 333.0 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3385 FOG Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 k141_12404_2 1278309.KB907099_gene3129 6.82e-38 129.0 2DZDS@1|root,32V82@2|Bacteria,1N6EX@1224|Proteobacteria,1S9VE@1236|Gammaproteobacteria,1XKPN@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6043_2 187272.Mlg_0395 5.62e-87 265.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1WW3U@135613|Chromatiales 135613|Chromatiales T PFAM PhoH family protein - - - ko:K06217 - - - - ko00000 - - - PhoH k141_16522_1 1523503.JPMY01000037_gene1742 1.95e-79 246.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k141_3338_1 1163617.SCD_n00030 1.29e-163 475.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria 28216|Betaproteobacteria NU type II secretion system protein E gspE1 - - ko:K02454,ko:K02652,ko:K12276 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_1925_1 1129794.C427_3341 7e-27 105.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,468DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB k141_1925_2 491952.Mar181_0941 1.3e-07 51.6 COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1S5D7@1236|Gammaproteobacteria,1XMDR@135619|Oceanospirillales 135619|Oceanospirillales E 5-carboxymethyl-2-hydroxymuconate isomerase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - - k141_8242_1 571166.KI421509_gene1733 1.3e-147 420.0 COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2U0GD@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Formyl transferase, C-terminal domain - - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_11014_1 1095769.CAHF01000018_gene767 5.22e-25 101.0 COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - k141_17999_1 323261.Noc_3082 2.34e-77 239.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales 135613|Chromatiales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_3968_1 1278309.KB907109_gene3283 4.5e-45 160.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1XHEE@135619|Oceanospirillales 135619|Oceanospirillales P Chloride channel - - - - - - - - - - - - CBS,Voltage_CLC k141_3968_2 1278309.KB907109_gene3282 2.27e-113 329.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1XJJR@135619|Oceanospirillales 135619|Oceanospirillales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_3968_3 1278309.KB907109_gene3281 2.71e-238 659.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XII2@135619|Oceanospirillales 135619|Oceanospirillales H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_8832_1 545276.KB898725_gene899 3.97e-41 147.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1WWYR@135613|Chromatiales 135613|Chromatiales S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA k141_1990_1 1121472.AQWN01000002_gene2131 1.6e-36 132.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,2629Q@186807|Peptococcaceae 186801|Clostridia M PFAM Transglycosylase SLT domain yjbJ - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT k141_15976_1 1288826.MSNKSG1_13087 0.0 1472.0 COG0210@1|root,COG0210@2|Bacteria,1MXWE@1224|Proteobacteria,1RP5D@1236|Gammaproteobacteria,466UN@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD-2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_15976_2 1288826.MSNKSG1_13092 1.88e-226 631.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,1T1FC@1236|Gammaproteobacteria,46D4T@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family oprF - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OprF,TSP_3 k141_15976_3 1288826.MSNKSG1_13097 1.68e-107 310.0 2EJ56@1|root,33CWD@2|Bacteria,1NMPP@1224|Proteobacteria,1SIQG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_15976_4 1288826.MSNKSG1_13102 3.3e-269 739.0 2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,466D3@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0500 SAM-dependent methyltransferases PP0279 - - - - - - - - - - - Methyltransf_32 k141_15976_5 1479237.JMLY01000001_gene269 2.48e-129 372.0 COG0565@1|root,COG0565@2|Bacteria,1MUKP@1224|Proteobacteria,1RMZX@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA lasT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_15976_6 1288826.MSNKSG1_13112 8.8e-300 818.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,46524@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0665 Glycine D-amino acid oxidases (deaminating) - - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_15976_7 1288826.MSNKSG1_13117 5.3e-200 553.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,465XC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 k141_15976_8 1288826.MSNKSG1_13122 1.51e-191 531.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,464EP@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0084 Mg-dependent DNase ycfH GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_15976_9 1288826.MSNKSG1_13127 2.52e-282 772.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,464BT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2206 HD-GYP domain - - - - - - - - - - - - DUF3391,HD,HD_5 k141_15976_10 1288826.MSNKSG1_13132 0.0 974.0 COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,464YD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1283 Na phosphate symporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans k141_15976_11 1288826.MSNKSG1_13137 0.0 1215.0 COG3221@1|root,COG5001@1|root,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,46DBB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_8342_2 500635.MITSMUL_04374 5.41e-17 80.1 COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes 909932|Negativicutes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep,Hexapep_2 k141_11108_1 1232683.ADIMK_0105 0.000117 43.1 2E4UV@1|root,32ZP8@2|Bacteria,1N4X4@1224|Proteobacteria,1SER2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB k141_11108_2 1122207.MUS1_11620 4.11e-286 790.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XIF1@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_11108_3 1122599.AUGR01000004_gene2163 2.18e-30 115.0 COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,1S5P4@1236|Gammaproteobacteria,1XR0W@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_11108_4 259536.Psyc_1963 5.31e-48 166.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,3NR33@468|Moraxellaceae 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_3432_1 1237149.C900_00016 2.03e-83 260.0 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_2686_1 349521.HCH_06299 5.04e-26 112.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_8 k141_4822_1 1380600.AUYN01000009_gene2087 7.9e-27 104.0 28RWK@1|root,2ZE8S@2|Bacteria,4P8ZJ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_4822_2 1380600.AUYN01000009_gene2088 3.45e-14 68.9 COG1959@1|root,COG1959@2|Bacteria 2|Bacteria K 2 iron, 2 sulfur cluster binding - - - - - - - - - - - - Rrf2 k141_18110_1 1232437.KL662077_gene1903 2.63e-17 73.9 2EMP1@1|root,33FBF@2|Bacteria,1NPTU@1224|Proteobacteria,432U4@68525|delta/epsilon subdivisions,2WXUI@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_19444_2 1230343.CANP01000042_gene3185 3.25e-81 258.0 COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1JDR9@118969|Legionellales 118969|Legionellales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_22221_1 187272.Mlg_1309 4.35e-85 262.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1WWQ4@135613|Chromatiales 135613|Chromatiales K PFAM sigma-54 factor interaction domain-containing protein - - - - - - - - - - - - HTH_8,Sigma54_activat k141_1354_1 1288826.MSNKSG1_10823 1.2e-162 454.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,467VC@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_1354_2 1288826.MSNKSG1_10818 2.37e-95 284.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,464BE@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_18745_1 1397528.Q671_01110 3.3e-189 536.0 COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,1XPCB@135619|Oceanospirillales 135619|Oceanospirillales L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3 k141_18745_2 1129794.C427_2251 3.06e-69 220.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_16625_1 156889.Mmc1_0042 1.61e-39 139.0 COG1876@1|root,COG1876@2|Bacteria,1RB64@1224|Proteobacteria 1224|Proteobacteria M peptidase M15B and M15C DD-carboxypeptidase VanY - - - - - - - - - - - - VanY k141_16625_2 1121438.JNJA01000012_gene1554 1.22e-61 204.0 COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2M8TP@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - Peptidase_M99,Peptidase_M99_C k141_20783_1 716928.AJQT01000076_gene168 7.14e-54 182.0 COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1NR5P@1224|Proteobacteria,2UPVK@28211|Alphaproteobacteria,4BMNK@82115|Rhizobiaceae 28211|Alphaproteobacteria GK ROK family xylR - - - - - - - - - - - HTH_24,ROK k141_6154_1 1278309.KB907102_gene64 1.47e-234 647.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1XIQQ@135619|Oceanospirillales 135619|Oceanospirillales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_6154_2 1278309.KB907102_gene65 3.81e-253 702.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XHGA@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_6154_3 1278309.KB907102_gene66 9.5e-241 667.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XHZM@135619|Oceanospirillales 135619|Oceanospirillales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_6154_4 1278309.KB907102_gene67 1.53e-160 457.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1XIP2@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_8919_1 1126627.BAWE01000005_gene5999 5.52e-28 117.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,3JSQ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Uncharacterized protein family (UPF0051) sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 k141_15190_1 1157490.EL26_08730 2.3e-11 67.8 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,278A2@186823|Alicyclobacillaceae 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_8359_1 1278309.KB907111_gene3358 1e-170 498.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XHDW@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_18762_1 1278309.KB907101_gene679 2.11e-150 432.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XIPG@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_13907_1 396588.Tgr7_1567 7.61e-66 213.0 COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,1T2FP@1236|Gammaproteobacteria,1WWXW@135613|Chromatiales 135613|Chromatiales C PFAM 2Fe-2S iron-sulfur cluster binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2 k141_6171_1 204773.HEAR1958 1.11e-29 112.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,474WZ@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF1178) - - - - - - - - - - - - DUF1178 k141_6171_2 323261.Noc_1416 2.09e-104 318.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1T05M@1236|Gammaproteobacteria,1WXY2@135613|Chromatiales 135613|Chromatiales P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_6171_3 1121104.AQXH01000001_gene1059 9.92e-17 80.1 COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,1IU9C@117747|Sphingobacteriia 976|Bacteroidetes O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_6171_4 519989.ECTPHS_04009 1.05e-46 172.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_21562_1 1168067.JAGP01000001_gene1160 7.32e-75 237.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,460CV@72273|Thiotrichales 72273|Thiotrichales G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_21562_2 1168067.JAGP01000001_gene1159 3.35e-11 63.2 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales 72273|Thiotrichales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_8940_1 261292.Nit79A3_3464 1.48e-13 71.6 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales 28216|Betaproteobacteria L RNA polymerase recycling family C-terminal - - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N k141_8940_2 1162668.LFE_2141 2.64e-07 54.7 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis resA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - AhpC-TSA,Pyr_redox_2,Redoxin,Thioredoxin k141_17335_1 1392540.P256_00056 1.52e-21 96.3 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria,3NMKN@468|Moraxellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k141_20801_1 161934.XP_010668845.1 1.92e-54 175.0 COG1007@1|root,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae 33090|Viridiplantae C NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient ndhB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.6.5.3 ko:K02992,ko:K05573 ko00190,ko01100,ko03010,map00190,map01100,map03010 M00145,M00178,M00179 R11945 RC00061 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - Proton_antipo_M k141_22235_2 1288826.MSNKSG1_06523 0.0 1410.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_11732_1 2340.JV46_28240 9.44e-65 219.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_13908_1 999141.GME_15385 1.26e-34 120.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XKNG@135619|Oceanospirillales 135619|Oceanospirillales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_13908_2 314278.NB231_16063 5.2e-09 57.4 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1WWAA@135613|Chromatiales 135613|Chromatiales O peptidylprolyl isomerase - - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 k141_14501_1 351348.Maqu_2338 1.3e-09 58.2 COG3250@1|root,COG3250@2|Bacteria,1R87I@1224|Proteobacteria,1RZ7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Protein of unknown function (DUF2804) - - - - - - - - - - - - DUF2804 k141_14501_2 225937.HP15_730 9.37e-36 128.0 COG2867@1|root,COG2867@2|Bacteria,1QU02@1224|Proteobacteria,1T3BK@1236|Gammaproteobacteria 1236|Gammaproteobacteria I START domain - - - - - - - - - - - - START k141_8360_1 1121440.AUMA01000006_gene1594 1.17e-44 152.0 COG3945@1|root,COG3945@2|Bacteria,1RG8J@1224|Proteobacteria,42S6P@68525|delta/epsilon subdivisions,2WNYW@28221|Deltaproteobacteria,2MCW2@213115|Desulfovibrionales 28221|Deltaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_10402_3 317025.Tcr_0811 5.8e-94 280.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,460FZ@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_10402_4 323261.Noc_2569 1.75e-08 55.5 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_15992_1 1288826.MSNKSG1_10763 2.74e-208 575.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,465ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria E reductase metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0117,iSBO_1134.SBO_3961 MTHFR k141_15992_3 1288826.MSNKSG1_10768 1.57e-180 502.0 COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,1RRI5@1236|Gammaproteobacteria,46A2A@72275|Alteromonadaceae 1236|Gammaproteobacteria ET belongs to the bacterial solute-binding protein 3 family glnH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - SBP_bac_3 k141_15992_4 1288826.MSNKSG1_10773 5.84e-148 417.0 COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,1RS0Y@1236|Gammaproteobacteria,46B43@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0765 ABC-type amino acid transport system, permease component glnP - - ko:K10037 ko02010,map02010 M00227 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.2 - - BPD_transp_1 k141_15992_5 1288826.MSNKSG1_10778 7.67e-170 475.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,469ND@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1126 ABC-type polar amino acid transport system, ATPase component glnQ - 3.6.3.21 ko:K02028,ko:K02029,ko:K10038 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 - - ABC_tran k141_15992_6 1288826.MSNKSG1_10783 1.67e-108 313.0 2ED3C@1|root,33708@2|Bacteria,1NETB@1224|Proteobacteria,1SDJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2505) - - - - - - - - - - - - DUF2505 k141_15992_7 1288826.MSNKSG1_10788 0.0 907.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,465KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Aminotran_3 k141_15992_8 1288826.MSNKSG1_10793 3.98e-62 196.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_625_2 225937.HP15_3763 1.13e-31 134.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,464KE@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_17336_1 396588.Tgr7_2294 1.66e-60 201.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_15191_1 1278309.KB907100_gene1948 3.52e-62 198.0 COG3440@1|root,COG3440@2|Bacteria,1NHIB@1224|Proteobacteria,1S546@1236|Gammaproteobacteria,1XPDU@135619|Oceanospirillales 135619|Oceanospirillales V Domain of unknown function (DUF3883) - - - - - - - - - - - - DUF3883 k141_4836_2 1162668.LFE_1242 7.31e-33 119.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_24 k141_4836_3 713586.KB900536_gene1956 7.1e-15 77.4 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase type 11 - - - - - - - - - - - - MerC,Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_4836_4 159087.Daro_2280 4.21e-48 165.0 COG4063@1|root,COG4063@2|Bacteria 2|Bacteria H Domain of unknown function (DUF4346) - - 2.1.1.86 ko:K00577 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00357,M00567 R04347 RC00035,RC00113,RC02892 ko00000,ko00001,ko00002,ko01000 - - - DUF4346,MtrA k141_22236_1 630626.EBL_c31670 2.12e-61 197.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria 1236|Gammaproteobacteria P PFAM Uncharacterised protein family UPF0066 yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - - - - - - - - - - UPF0066 k141_9628_1 1288826.MSNKSG1_08123 3.63e-102 305.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,464K3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rsmC - 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_9628_2 1288826.MSNKSG1_08128 1.21e-128 372.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,465NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_13909_1 223926.28805273 1.66e-119 347.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XSWE@135623|Vibrionales 135623|Vibrionales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_14502_1 1288826.MSNKSG1_14037 2.13e-138 395.0 COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,1RNSM@1236|Gammaproteobacteria,466Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily pagO - - - - - - - - - - - EamA k141_6174_1 556269.ACDQ01000002_gene1135 1.71e-39 150.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,472UR@75682|Oxalobacteraceae 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_18763_1 1049564.TevJSym_aw00120 1.58e-137 412.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster dsrL - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,NADH_4Fe-4S,Pyr_redox_2 k141_8361_1 1177154.Y5S_00766 1.81e-121 361.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XI5M@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_11733_1 1499967.BAYZ01000009_gene5347 4.99e-85 266.0 COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria 2|Bacteria S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_1369_1 562743.JH976434_gene850 3.03e-07 55.5 COG0564@1|root,COG0564@2|Bacteria,1TSPG@1239|Firmicutes,4HBGS@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA - 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2,S4_2 k141_1369_2 1278309.KB907108_gene1585 6.35e-188 528.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,1RMCE@1236|Gammaproteobacteria,1XINK@135619|Oceanospirillales 135619|Oceanospirillales C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase k141_1369_3 13684.SNOT_07805 2.56e-07 51.6 COG3193@1|root,2SUKI@2759|Eukaryota,3A5SY@33154|Opisthokonta,3P5U5@4751|Fungi,3QXIZ@4890|Ascomycota,20508@147541|Dothideomycetes,4KIGR@92860|Pleosporales 4751|Fungi S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_13910_1 425104.Ssed_2174 7.62e-117 353.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,2Q9PS@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_15993_1 1278309.KB907099_gene2561 3.67e-72 235.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RZNZ@1236|Gammaproteobacteria,1XKDT@135619|Oceanospirillales 135619|Oceanospirillales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_15993_2 314275.MADE_000001022010 6.1e-51 176.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,464MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_22237_1 1177179.A11A3_08670 2.4e-80 249.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XI4K@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_4918_2 631362.Thi970DRAFT_04860 7.23e-33 125.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1WWIC@135613|Chromatiales 135613|Chromatiales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_13985_1 426117.M446_6155 5.9e-32 118.0 COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,2UFXH@28211|Alphaproteobacteria,1JVP9@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ k141_13985_2 1042375.AFPL01000013_gene2469 6.93e-38 138.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,46532@72275|Alteromonadaceae 1236|Gammaproteobacteria F Amidohydrolase family hydA - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_15389_1 1288826.MSNKSG1_12842 7.06e-133 379.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,467M9@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0634 Hypoxanthine-guanine phosphoribosyltransferase hpt GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_15389_2 1288826.MSNKSG1_12847 8.22e-114 327.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,467KU@72275|Alteromonadaceae 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_15389_3 1288826.MSNKSG1_12852 1.58e-206 572.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,46476@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - iZ_1308.Z5639 UbiA k141_15389_4 1288826.MSNKSG1_12857 4.47e-160 449.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,464AU@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoB GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_15389_5 1288826.MSNKSG1_12862 1.17e-48 166.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,465EB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_1436_1 1408444.JHYC01000008_gene1309 6.72e-08 52.8 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1JCNU@118969|Legionellales 118969|Legionellales S Belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_9110_1 1124991.MU9_2905 1.84e-83 261.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k141_19563_1 1288826.MSNKSG1_05401 7.63e-291 816.0 COG1196@1|root,COG1196@2|Bacteria,1QU97@1224|Proteobacteria,1T3AS@1236|Gammaproteobacteria,467TR@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0419 ATPase involved in DNA repair - - - - - - - - - - - - AAA_23,AAA_27 k141_19563_2 443152.MDG893_07760 3.52e-80 265.0 COG1061@1|root,COG2227@1|root,COG2932@1|root,COG3886@1|root,COG1061@2|Bacteria,COG2227@2|Bacteria,COG2932@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4657B@72275|Alteromonadaceae 1236|Gammaproteobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,Methyltransf_25,PLDc_2,ResIII k141_7725_1 1121459.AQXE01000018_gene2111 3.22e-101 308.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42PMJ@68525|delta/epsilon subdivisions,2X5FZ@28221|Deltaproteobacteria,2MGQC@213115|Desulfovibrionales 28221|Deltaproteobacteria EGP Sugar (and other) transporter - - - ko:K03762 - - - - ko00000,ko02000 2.A.1.6.4 - - MFS_1,Sugar_tr k141_7725_3 768671.ThimaDRAFT_1213 2.53e-52 171.0 COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1S6Y0@1236|Gammaproteobacteria,1WYNQ@135613|Chromatiales 135613|Chromatiales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_21649_1 1288826.MSNKSG1_12537 1.3e-134 384.0 COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,1S64F@1236|Gammaproteobacteria,467WH@72275|Alteromonadaceae 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_21649_2 1288826.MSNKSG1_12542 3.61e-266 728.0 COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,1RNBV@1236|Gammaproteobacteria,4655W@72275|Alteromonadaceae 1236|Gammaproteobacteria E Carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_21649_3 1288826.MSNKSG1_12547 2.23e-188 525.0 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,1RQ3U@1236|Gammaproteobacteria,466HM@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2113 ABC-type proline glycine betaine transport systems, periplasmic components opuAC - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_8410_1 1198232.CYCME_1822 5.41e-117 347.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales 72273|Thiotrichales E Aminotransferase aspC2 - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_11222_1 1249627.D779_0089 3.49e-25 105.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales 135613|Chromatiales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_11222_2 1123393.KB891318_gene2168 7.85e-59 204.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,1KSBZ@119069|Hydrogenophilales 119069|Hydrogenophilales P TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_20267_1 686340.Metal_0120 4.15e-58 198.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_13301_1 5888.CAK87471 2.97e-13 68.9 COG5194@1|root,KOG2930@2759|Eukaryota 2759|Eukaryota DO NEDD8 transferase activity RBX1 GO:0000082,GO:0000151,GO:0000152,GO:0000165,GO:0000209,GO:0000278,GO:0000715,GO:0001666,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006508,GO:0006511,GO:0006513,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007346,GO:0008134,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009628,GO:0009889,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010265,GO:0010389,GO:0010468,GO:0010498,GO:0010556,GO:0010564,GO:0010604,GO:0010646,GO:0010648,GO:0010948,GO:0010972,GO:0016043,GO:0016055,GO:0016310,GO:0016567,GO:0016740,GO:0019005,GO:0019219,GO:0019221,GO:0019222,GO:0019538,GO:0019787,GO:0019788,GO:0019899,GO:0019941,GO:0022402,GO:0022607,GO:0023014,GO:0023051,GO:0023052,GO:0023057,GO:0030111,GO:0030162,GO:0030163,GO:0030178,GO:0030674,GO:0031146,GO:0031323,GO:0031325,GO:0031326,GO:0031329,GO:0031331,GO:0031334,GO:0031461,GO:0031462,GO:0031463,GO:0031464,GO:0031465,GO:0031466,GO:0031467,GO:0031625,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032434,GO:0032436,GO:0032446,GO:0032991,GO:0033554,GO:0033683,GO:0034097,GO:0034450,GO:0034622,GO:0034641,GO:0035361,GO:0035556,GO:0036211,GO:0036293,GO:0036294,GO:0042176,GO:0042221,GO:0042769,GO:0043161,GO:0043170,GO:0043224,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043412,GO:0043618,GO:0043620,GO:0043632,GO:0043687,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045116,GO:0045732,GO:0045786,GO:0045862,GO:0045930,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051276,GO:0051603,GO:0051606,GO:0051716,GO:0051726,GO:0060090,GO:0060255,GO:0060828,GO:0061136,GO:0061418,GO:0061630,GO:0061659,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070482,GO:0070498,GO:0070555,GO:0070647,GO:0070887,GO:0070911,GO:0071310,GO:0071345,GO:0071347,GO:0071453,GO:0071456,GO:0071704,GO:0071824,GO:0071840,GO:0080008,GO:0080090,GO:0090090,GO:0090304,GO:0090305,GO:0097602,GO:0140096,GO:0198738,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902494,GO:1902749,GO:1902750,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1905114,GO:1990234,GO:2000058,GO:2000060,GO:2000112,GO:2001141 2.3.2.32 ko:K03868 ko03420,ko04066,ko04110,ko04111,ko04114,ko04120,ko04141,ko04310,ko04341,ko04350,ko04710,ko05200,ko05211,map03420,map04066,map04110,map04111,map04114,map04120,map04141,map04310,map04341,map04350,map04710,map05200,map05211 M00379,M00380,M00381,M00382,M00383,M00384,M00385,M00386,M00387,M00407,M00411 - - ko00000,ko00001,ko00002,ko01000,ko03400,ko04121 - - - zf-rbx1 k141_3527_1 1165841.SULAR_09819 2.36e-42 147.0 COG0697@1|root,COG0697@2|Bacteria,1N2BC@1224|Proteobacteria 1224|Proteobacteria EG Protein of unknown function (DUF2569) - - - - - - - - - - - - DUF2569 k141_16072_1 335543.Sfum_2298 1.12e-12 75.5 COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MRYH@213462|Syntrophobacterales 28221|Deltaproteobacteria S PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_4,TPR_8 k141_7030_1 396588.Tgr7_0039 2.24e-61 211.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RWW8@1236|Gammaproteobacteria,1X085@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_13986_1 672.VV93_v1c29710 8.13e-39 142.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1XTBG@135623|Vibrionales 135623|Vibrionales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k141_12605_1 218491.ECA3996 2.74e-52 176.0 COG0009@1|root,COG0551@1|root,COG0009@2|Bacteria,COG0551@2|Bacteria,1MX2E@1224|Proteobacteria,1RQ85@1236|Gammaproteobacteria,1MRN3@122277|Pectobacterium 1236|Gammaproteobacteria L Topoisomerase DNA binding C4 zinc finger yrdD GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005506,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0097159,GO:1901363 - ko:K07479 - - - - ko00000 - - - zf-C4_Topoisom k141_12605_2 857087.Metme_4265 0.0 1035.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XDRF@135618|Methylococcales 135618|Methylococcales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_12605_3 1123377.AUIV01000006_gene1560 2.52e-44 150.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1X63Y@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_41_1 519989.ECTPHS_00230 3.58e-65 204.0 COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria 1236|Gammaproteobacteria F COG0209 Ribonucleotide reductase, alpha subunit nrdJb - - - - - - - - - - - - k141_11892_1 566466.NOR53_3280 1.68e-47 163.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1J85J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_7726_1 1250006.JHZZ01000001_gene2435 4.04e-88 267.0 COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1HX0W@117743|Flavobacteriia,3VV1M@52959|Polaribacter 976|Bacteroidetes H Delta-aminolevulinic acid dehydratase hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_18872_1 1121374.KB891580_gene1789 3.63e-97 302.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_18872_2 335283.Neut_0749 0.000248 46.2 COG5581@1|root,COG5581@2|Bacteria,1MX00@1224|Proteobacteria,2VQEK@28216|Betaproteobacteria,37203@32003|Nitrosomonadales 28216|Betaproteobacteria M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility ycgR - - - - - - - - - - - PilZ,YcgR k141_15390_1 1278309.KB907107_gene1689 1.11e-154 452.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales 135619|Oceanospirillales O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_18172_2 766499.C357_21107 2.15e-74 230.0 COG3218@1|root,COG3218@2|Bacteria,1RI22@1224|Proteobacteria,2UB1D@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system auxiliary component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux k141_14705_1 1288826.MSNKSG1_14907 3.71e-93 288.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,464KE@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_14705_2 1288826.MSNKSG1_14902 4.05e-50 158.0 COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,468GN@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF1653 k141_14705_3 1288826.MSNKSG1_14897 2.84e-115 342.0 COG2056@1|root,COG2056@2|Bacteria,1N8U2@1224|Proteobacteria,1RRW5@1236|Gammaproteobacteria,469EN@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease - - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - - Na_H_antiport_2,Na_H_antiporter k141_9111_1 279714.FuraDRAFT_3749 1.17e-40 144.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2VMWZ@28216|Betaproteobacteria,2KPI1@206351|Neisseriales 206351|Neisseriales IQ Psort location Cytoplasmic, score - - - - - - - - - - - - adh_short k141_5627_1 1278309.KB907112_gene3332 1.19e-24 100.0 COG3203@1|root,COG3203@2|Bacteria,1NA7U@1224|Proteobacteria,1RPXP@1236|Gammaproteobacteria,1XIHX@135619|Oceanospirillales 135619|Oceanospirillales M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_5627_2 1278309.KB907099_gene2588 5.25e-313 856.0 COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,1XH3Q@135619|Oceanospirillales 135619|Oceanospirillales P ATPases associated with a variety of cellular activities - - - ko:K05776 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 - - - ABC_tran k141_5627_3 1278309.KB907099_gene2589 0.0 927.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1XIH7@135619|Oceanospirillales 135619|Oceanospirillales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_5627_4 1042375.AFPL01000038_gene1543 5.23e-190 533.0 COG2207@1|root,COG2207@2|Bacteria,1RG3C@1224|Proteobacteria,1S50G@1236|Gammaproteobacteria,46B4R@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_5627_5 1042375.AFPL01000038_gene1544 4.69e-113 325.0 COG1917@1|root,COG1917@2|Bacteria,1N0BS@1224|Proteobacteria,1SBE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_7 k141_1437_1 398580.Dshi_0979 2.98e-140 409.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_2129_1 1288298.rosmuc_03313 3.5e-118 363.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,46NA4@74030|Roseovarius 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_4206_1 1288826.MSNKSG1_17900 0.0 1204.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,464B1@72275|Alteromonadaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_4206_2 1288826.MSNKSG1_17905 8.07e-314 858.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,464FE@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr k141_4206_3 1288826.MSNKSG1_17910 1.26e-100 294.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,466WC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_4206_4 1288826.MSNKSG1_17915 3.02e-172 484.0 COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,1SAQC@1236|Gammaproteobacteria,46856@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Pilus assembly protein mshI - - ko:K12279 - - - - ko00000,ko02044 - - - - k141_4206_5 1288826.MSNKSG1_17920 7.39e-125 357.0 COG3166@1|root,COG3166@2|Bacteria,1N82E@1224|Proteobacteria,1RTX3@1236|Gammaproteobacteria,4696N@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Fimbrial assembly protein (PilN) - - - ko:K12279 - - - - ko00000,ko02044 - - - PilN k141_4206_6 1288826.MSNKSG1_17925 4.22e-07 50.1 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,1S8XS@1236|Gammaproteobacteria,46DFF@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretion system (T2SS), protein M mshJ - - ko:K12280 - - - - ko00000,ko02044 - - - PilO,T2SSM k141_20982_2 266779.Meso_2003 1.4e-10 68.2 COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,43HJI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria D Essential cell division protein ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_20982_3 1198232.CYCME_2280 2.41e-69 220.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4606P@72273|Thiotrichales 72273|Thiotrichales F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_8411_1 1123393.KB891317_gene2319 3.36e-75 229.0 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 k141_18173_2 1479237.JMLY01000001_gene18 2.62e-30 108.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,468CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03116,ko:K03425 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_11893_2 105559.Nwat_2073 1.02e-21 92.8 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales 135613|Chromatiales BQ PFAM histone deacetylase superfamily - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl k141_5628_1 367336.OM2255_03600 7.95e-97 286.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family cfxE - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_16073_1 267608.RSc3052 3.16e-07 51.2 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,1K0BX@119060|Burkholderiaceae 28216|Betaproteobacteria F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_16073_2 998674.ATTE01000001_gene2974 1.69e-18 84.3 COG3473@1|root,COG3473@2|Bacteria,1RB05@1224|Proteobacteria,1S5KQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Asp Glu racemase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race k141_15391_1 382464.ABSI01000012_gene2256 4.02e-93 281.0 COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,2ITMF@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Transaldolase/Fructose-6-phosphate aldolase - - - - - - - - - - - - TAL_FSA k141_6303_1 395493.BegalDRAFT_1884 3.96e-97 307.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,45ZUB@72273|Thiotrichales 72273|Thiotrichales C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_2828_2 1049564.TevJSym_at00140 3.79e-81 247.0 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1J69Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.1.1.104,4.2.1.109 ko:K08964,ko:K22130 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_2828_3 211114.JOEF01000042_gene6053 1.35e-56 184.0 COG1791@1|root,COG1791@2|Bacteria,2IAG7@201174|Actinobacteria,4E2Z1@85010|Pseudonocardiales 201174|Actinobacteria S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD - 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD k141_2828_4 697282.Mettu_2014 6.18e-86 261.0 COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1XE85@135618|Methylococcales 135618|Methylococcales C Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC - 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - - k141_10508_1 207954.MED92_15043 3.7e-195 551.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHXR@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_11223_1 1042375.AFPL01000032_gene1013 5.43e-58 181.0 COG4766@1|root,COG4766@2|Bacteria,1R6MF@1224|Proteobacteria,1T17A@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Ethanolamine utilisation protein EutQ - - - ko:K04030 - - - - ko00000 - - - EutQ k141_6325_5 1288826.MSNKSG1_16311 2.31e-84 251.0 2E6K1@1|root,3316U@2|Bacteria,1NCHT@1224|Proteobacteria,1S72Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6325_6 1288826.MSNKSG1_16306 4.03e-87 257.0 COG3339@1|root,COG3339@2|Bacteria,1N9BI@1224|Proteobacteria,1SC8Z@1236|Gammaproteobacteria,4692I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 k141_6325_7 1288826.MSNKSG1_16301 6.9e-162 456.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,4658K@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1291 Flagellar motor component motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_6325_8 1288826.MSNKSG1_16296 3.67e-201 559.0 COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,463XV@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1360 Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_6325_9 1288826.MSNKSG1_16291 2.61e-171 485.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,465N3@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_20301_1 555778.Hneap_0792 1.82e-135 390.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1SZ87@1236|Gammaproteobacteria,1X2J8@135613|Chromatiales 135613|Chromatiales P PFAM ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_2845_1 1122197.ATWI01000008_gene3005 1.45e-47 173.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S1KB@1236|Gammaproteobacteria,46CZ2@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_2845_2 1288826.MSNKSG1_16316 0.0 864.0 COG0415@1|root,COG0415@2|Bacteria,1MWRT@1224|Proteobacteria,1RN1P@1236|Gammaproteobacteria,465QF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family cry GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_2845_3 396588.Tgr7_0959 3.93e-154 450.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X0IF@135613|Chromatiales 135613|Chromatiales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3,PAS_4 k141_2845_4 1288826.MSNKSG1_16321 4.99e-273 746.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,464JN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_2845_5 1288826.MSNKSG1_16326 2.97e-134 380.0 COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,466VX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator nemR - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_13,TetR_N k141_2845_6 1288826.MSNKSG1_16331 8.65e-39 138.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_3550_1 666681.M301_1585 1.91e-26 107.0 28KE4@1|root,2ZA0D@2|Bacteria,1MXZT@1224|Proteobacteria,2VNI6@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_3550_2 551789.ATVJ01000001_gene549 4.09e-37 134.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2U3PI@28211|Alphaproteobacteria,43XRT@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_5667_2 187272.Mlg_2696 2.72e-45 147.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales 135613|Chromatiales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic k141_5667_3 1049564.TevJSym_bv00080 7.52e-30 117.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1J594@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_21025_1 1415756.JQMY01000001_gene2783 2.44e-36 135.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,2PCEY@252301|Oceanicola 28211|Alphaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_21025_2 999550.KI421507_gene907 1.11e-28 113.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K03732,ko:K11927 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_7169_1 1232683.ADIMK_4115 2.39e-129 379.0 COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,1T1QB@1236|Gammaproteobacteria 1236|Gammaproteobacteria C TIGRFAM CitB domain protein tcuB - - ko:K13795 - - - - ko00000 - - - - k141_6457_1 90813.JQMT01000001_gene2180 2.22e-92 279.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales 72273|Thiotrichales S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_12068_1 314264.ROS217_10787 3.35e-134 384.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2TQT6@28211|Alphaproteobacteria,46QH0@74030|Roseovarius 28211|Alphaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K02050,ko:K15577 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17 - - BPD_transp_1 k141_5060_2 1278309.KB907101_gene746 3.84e-152 430.0 COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria,1XJ77@135619|Oceanospirillales 135619|Oceanospirillales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_5060_3 1278309.KB907101_gene747 7.05e-92 272.0 COG1670@1|root,COG1670@2|Bacteria,1PY0X@1224|Proteobacteria,1S725@1236|Gammaproteobacteria,1XK6M@135619|Oceanospirillales 135619|Oceanospirillales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_5060_4 1278309.KB907101_gene748 7.75e-136 392.0 COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1SZQ8@1236|Gammaproteobacteria,1XJVT@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_5060_5 1278309.KB907101_gene749 9.05e-60 189.0 COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,1SCZH@1236|Gammaproteobacteria,1XM4P@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF1499 k141_5060_6 1278309.KB907101_gene750 2.21e-101 295.0 COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,1S45M@1236|Gammaproteobacteria,1XJHC@135619|Oceanospirillales 135619|Oceanospirillales S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_5060_7 443152.MDG893_02385 1.91e-46 157.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria,4665I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_16935_1 523791.Kkor_2617 5.34e-45 158.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1XIPZ@135619|Oceanospirillales 135619|Oceanospirillales S protein containing LysM domain - - - - - - - - - - - - LysM k141_16935_2 1116472.MGMO_91c00220 3.8e-37 138.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XE4B@135618|Methylococcales 135618|Methylococcales L PFAM DNA recombination-mediator protein A - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_18325_1 1230343.CANP01000023_gene1546 6.88e-11 61.6 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1JDQ4@118969|Legionellales 118969|Legionellales S SURF1 family - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_18325_2 283942.IL0255 2.49e-05 50.1 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1S85U@1236|Gammaproteobacteria,2QG6D@267893|Idiomarinaceae 1236|Gammaproteobacteria S signal sequence binding VVA1110 - - - - - - - - - - - - k141_21173_1 1122176.KB903565_gene3327 1.49e-82 263.0 COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,4NK7Y@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_11 k141_12768_1 1216007.AOPM01000086_gene856 2.18e-10 58.9 2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria,1SHSY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13460_2 596154.Alide2_2235 7.71e-68 218.0 COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,2VNBE@28216|Betaproteobacteria,4AG24@80864|Comamonadaceae 28216|Betaproteobacteria H PFAM amine oxidase - - - - - - - - - - - - Amino_oxidase k141_11393_1 572477.Alvin_2173 5.75e-92 292.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1WW3V@135613|Chromatiales 135613|Chromatiales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL - 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_19050_1 1288826.MSNKSG1_13222 2.09e-120 346.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,466JE@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_19050_2 1288826.MSNKSG1_13227 7.53e-135 382.0 COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,1S9RI@1236|Gammaproteobacteria,467ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3764 Sortase (surface protein transpeptidase) srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase k141_6458_1 243365.CV_2758 7.32e-81 259.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KPUY@206351|Neisseriales 206351|Neisseriales S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn k141_9244_2 1278309.KB907099_gene2800 6.56e-76 228.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XK2F@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_17657_1 1278309.KB907103_gene1146 2.51e-54 172.0 COG4859@1|root,COG4859@2|Bacteria,1RJ97@1224|Proteobacteria,1S7PB@1236|Gammaproteobacteria,1XK60@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2185) - - - - - - - - - - - - DUF2185 k141_17657_2 1278309.KB907103_gene1145 2.71e-87 257.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S6WS@1236|Gammaproteobacteria,1XRDQ@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the small heat shock protein (HSP20) family - - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 k141_17657_3 1121403.AUCV01000033_gene3627 2.65e-66 206.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,2MJVF@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM Appr-1-p processing domain protein ymdB - - - - - - - - - - - Macro k141_17657_4 1278309.KB907103_gene1143 7.32e-86 259.0 COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XKXC@135619|Oceanospirillales 135619|Oceanospirillales S AMMECR1 - - - - - - - - - - - - AMMECR1 k141_17657_5 1278309.KB907103_gene1142 1.37e-134 387.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XJIC@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_17657_6 1278309.KB907103_gene1141 3.16e-67 210.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1RW3Z@1236|Gammaproteobacteria,1XI20@135619|Oceanospirillales 135619|Oceanospirillales O Pyruvate formate lyase-activating protein - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM k141_7186_1 1121374.KB891591_gene3439 8.91e-113 349.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase fadE - 1.3.8.7 ko:K00249,ko:K06445 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_7186_2 396588.Tgr7_1720 1.78e-78 248.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1X2EF@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 k141_3724_1 1500893.JQNB01000001_gene151 2.33e-43 156.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1X2YZ@135614|Xanthomonadales 135614|Xanthomonadales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_3724_2 1415780.JPOG01000001_gene3064 2.59e-10 60.8 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1X4NV@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_19077_1 1279015.KB908467_gene484 1.2e-11 62.4 COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria,1T2RT@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Prokaryotic N-terminal methylation motif - - - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl k141_19077_2 745411.B3C1_05932 4.52e-25 100.0 COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1J9VA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU general secretion pathway protein xpsH - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl k141_19077_3 999541.bgla_1g01560 4.68e-37 131.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VT48@28216|Betaproteobacteria,1K86T@119060|Burkholderiaceae 28216|Betaproteobacteria U Type II secretion system (T2SS), protein G - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_19077_4 1279015.KB908467_gene481 2.29e-134 395.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1Y3IJ@135624|Aeromonadales 135624|Aeromonadales U General secretion pathway protein F exeF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_18352_2 751994.AGIG01000034_gene411 3.15e-58 182.0 COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1T8KW@1236|Gammaproteobacteria,1JB0B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Ribulose bisphosphate carboxylase, small chain - - - - - - - - - - - - RuBisCO_small k141_7912_1 998088.B565_1486 4.72e-69 230.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1Y3YN@135624|Aeromonadales 135624|Aeromonadales H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_12091_1 1188256.BASI01000003_gene2790 7.25e-93 278.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,3FDAP@34008|Rhodovulum 28211|Alphaproteobacteria S Aminomethyltransferase folate-binding domain ygfZ - - ko:K06980,ko:K22073 - - - - ko00000,ko01000,ko03016,ko03029 - - - GCV_T,GCV_T_C k141_20480_1 351348.Maqu_0210 1.52e-135 418.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria,46AHK@72275|Alteromonadaceae 1236|Gammaproteobacteria L Putative phage integrase - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_integrase k141_10708_1 1278309.KB907101_gene527 1.54e-296 820.0 COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIHK@135619|Oceanospirillales 135619|Oceanospirillales C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - Fer4_10,POR_N,TPP_enzyme_C k141_10708_2 1278309.KB907101_gene526 6.34e-113 328.0 COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,1S352@1236|Gammaproteobacteria,1XJEU@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR k141_1626_1 375451.RD1_1486 1.18e-128 376.0 COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,2TSYG@28211|Alphaproteobacteria,2P23S@2433|Roseobacter 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein smoE - - ko:K02027,ko:K10227 ko02010,map02010 M00200,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.5 - - SBP_bac_1 k141_4426_1 1049564.TevJSym_ba00260 1.68e-222 617.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria 1224|Proteobacteria E threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_4426_2 265072.Mfla_1048 1.89e-41 148.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,2KMC7@206350|Nitrosomonadales 206350|Nitrosomonadales E amino acid-binding ACT domain protein - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_5086_1 1266909.AUAG01000032_gene2385 0.0 896.0 COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,1RRZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M phospholipase C - - 3.1.4.3 ko:K01114 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919 - R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko01000,ko02042 - - - DUF756,Phosphoesterase k141_5086_2 637905.SVI_1952 1.64e-15 71.2 2DDH9@1|root,2ZI34@2|Bacteria,1P6H5@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_8594_1 1278309.KB907103_gene1206 2.62e-15 73.6 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RZ9D@1236|Gammaproteobacteria,1XHTK@135619|Oceanospirillales 135619|Oceanospirillales S Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM k141_8594_2 1278309.KB907103_gene1207 2.34e-119 346.0 COG1216@1|root,COG1216@2|Bacteria,1N6DH@1224|Proteobacteria,1T31U@1236|Gammaproteobacteria,1XRSX@135619|Oceanospirillales 135619|Oceanospirillales S COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_8594_3 1278309.KB907103_gene1208 2.26e-54 185.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XHBP@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter - - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_911_1 396588.Tgr7_2406 2.3e-94 291.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales 135613|Chromatiales M PFAM peptidase - - - - - - - - - - - - OapA,Peptidase_M23 k141_16947_1 395495.Lcho_4119 4.43e-05 49.3 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria 28216|Betaproteobacteria KLT PFAM Sel1 domain protein repeat-containing protein - - - ko:K07126 - - - - ko00000 - - - Sel1,TonB_C k141_16947_2 1278309.KB907099_gene2933 5.07e-51 174.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_5,Pyr_redox_3 k141_17658_1 519989.ECTPHS_10886 1.12e-72 234.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_2,FAD_binding_3,FAD_oxidored,GIDA,Lycopene_cycl k141_3725_1 767434.Fraau_2743 2.58e-13 69.3 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X34C@135614|Xanthomonadales 135614|Xanthomonadales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_3725_2 1500890.JQNL01000001_gene2368 5.55e-61 195.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1X3IF@135614|Xanthomonadales 135614|Xanthomonadales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_9245_2 472759.Nhal_2225 1.51e-67 217.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1X07Y@135613|Chromatiales 135613|Chromatiales E TIGRFAM amidase, hydantoinase carbamoylase - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_12092_1 519989.ECTPHS_02461 3.42e-10 65.5 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_4427_1 1288826.MSNKSG1_18360 7.06e-138 397.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,4647W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0516 DHBP_synthase,GTP_cyclohydro2 k141_13474_1 626887.J057_03295 1.77e-47 163.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,466TU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_13474_2 1123020.AUIE01000039_gene4684 4.1e-113 333.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1YCS9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D Phage integrase, N-terminal SAM-like domain xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_7187_1 187272.Mlg_0933 1.88e-11 62.4 COG5416@1|root,COG5416@2|Bacteria,1QGGK@1224|Proteobacteria,1TDW9@1236|Gammaproteobacteria,1X1XZ@135613|Chromatiales 135613|Chromatiales S Pfam:DUF1049 - - - ko:K08992 - - - - ko00000 - - - LapA_dom k141_7187_2 498211.CJA_2113 1.77e-46 152.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1FHET@10|Cellvibrio 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_7187_3 523791.Kkor_0898 3.59e-26 107.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XHWP@135619|Oceanospirillales 135619|Oceanospirillales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_9936_1 1278309.KB907099_gene2937 1.4e-193 549.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XIX5@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_16948_1 411901.BACCAC_02424 1.19e-25 105.0 COG0161@1|root,COG0502@1|root,COG0161@2|Bacteria,COG0502@2|Bacteria,4NEJN@976|Bacteroidetes,2FNNH@200643|Bacteroidia,4AN3D@815|Bacteroidaceae 976|Bacteroidetes H the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3,BATS,Radical_SAM k141_14883_1 402881.Plav_0407 3.86e-52 178.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,1JNEF@119043|Rhodobiaceae 28211|Alphaproteobacteria E Peptidase dimerisation domain argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_1627_1 1123248.KB893325_gene1224 4.48e-54 176.0 arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_1627_2 1042377.AFPJ01000032_gene2752 4.54e-34 130.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2183 Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_5087_1 1249480.B649_09935 1.53e-54 187.0 COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42Q8D@68525|delta/epsilon subdivisions,2YMC5@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Glycosyl transferases group 1 pglH1 - 2.4.1.292 ko:K17249 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_16949_1 1198452.Jab_2c34020 3.82e-35 132.0 COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria,472QT@75682|Oxalobacteraceae 28216|Betaproteobacteria C Protein of unknown function (DUF4080) - - - - - - - - - - - - B12-binding,DUF4080,Radical_SAM k141_19724_1 1124983.PFLCHA0_c37050 1.43e-05 44.7 2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,1SGBH@1236|Gammaproteobacteria,1YQYY@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Protein of unknown function (DUF2970) - - - - - - - - - - - - DUF2970 k141_19724_2 768671.ThimaDRAFT_4647 2.81e-205 599.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales 135613|Chromatiales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_4428_1 1123401.JHYQ01000030_gene3064 4.44e-97 312.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales 72273|Thiotrichales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_912_1 396588.Tgr7_1538 3.81e-169 483.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1WWFA@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydratase - - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_912_2 1122603.ATVI01000007_gene1449 4.31e-12 65.9 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1X4WZ@135614|Xanthomonadales 135614|Xanthomonadales EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_7914_1 83406.HDN1F_05420 5.24e-134 391.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1J5G5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family wecC - - ko:K02474 ko00520,map00520 - R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_7188_1 247639.MGP2080_09146 9.4e-14 67.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,1J6A6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0260 family ycgN - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_5088_1 314278.NB231_15218 1.05e-48 165.0 2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,1S67B@1236|Gammaproteobacteria,1X0TY@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_3727_1 1131553.JIBI01000026_gene77 5.88e-40 149.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,372ME@32003|Nitrosomonadales 28216|Betaproteobacteria I AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_9247_1 472759.Nhal_0529 6.26e-86 259.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_9247_2 1123400.KB904766_gene2953 1.77e-19 83.6 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,461AM@72273|Thiotrichales 72273|Thiotrichales U PFAM Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_4429_1 519989.ECTPHS_01334 1.47e-36 138.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1WX4I@135613|Chromatiales 135613|Chromatiales D PFAM peptidase - - - - - - - - - - - - Peptidase_M23 k141_12093_1 1123392.AQWL01000010_gene2312 1.47e-67 216.0 COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,2WGR7@28216|Betaproteobacteria,1KSBE@119069|Hydrogenophilales 119069|Hydrogenophilales G Sugar (and other) transporter - - - - - - - - - - - - MFS_1 k141_12093_2 580332.Slit_2852 3.99e-40 137.0 COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,2VWEE@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_12093_3 1123368.AUIS01000018_gene731 3.07e-35 124.0 COG1846@1|root,COG1846@2|Bacteria,1PC0Q@1224|Proteobacteria,1SXNR@1236|Gammaproteobacteria,2NDAB@225057|Acidithiobacillales 225057|Acidithiobacillales K Transcriptional regulator, MarR - - - ko:K06075 - - - - ko00000,ko03000 - - - MarR_2 k141_14885_2 1122164.JHWF01000010_gene2443 4.27e-40 150.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1JDMR@118969|Legionellales 118969|Legionellales M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase k141_16227_1 1288826.MSNKSG1_14697 0.0 1646.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,464X6@72275|Alteromonadaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_16227_2 1288826.MSNKSG1_14692 0.0 1365.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,464AV@72275|Alteromonadaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,AAA_30,UvrD_C_2 k141_18484_1 1278309.KB907100_gene1844 1.24e-187 526.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XH93@135619|Oceanospirillales 135619|Oceanospirillales J Elongation factor P--(R)-beta-lysine ligase genX - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_16368_1 1198452.Jab_1c01570 7.33e-23 96.3 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,4747E@75682|Oxalobacteraceae 28216|Betaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_16368_2 314607.KB13_359 3.56e-126 375.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,1KQCB@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3,OmpA k141_4577_1 870187.Thini_0507 9.44e-148 450.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales 72273|Thiotrichales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_22002_1 1168067.JAGP01000001_gene2181 8.97e-24 96.7 COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,1S0B9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised ACR, YagE family COG1723 - - - - - - - - - - - - DUF155 k141_22002_2 90813.JQMT01000001_gene2140 1.76e-60 195.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,460A9@72273|Thiotrichales 72273|Thiotrichales F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH,TusA k141_19877_1 1123368.AUIS01000025_gene1489 6.88e-51 180.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RZ20@1236|Gammaproteobacteria,2NE5G@225057|Acidithiobacillales 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - EAL,GGDEF k141_12956_1 1121935.AQXX01000122_gene5617 8.07e-135 432.0 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_10114_2 1452718.JBOY01000062_gene1724 2.87e-83 255.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k141_5252_1 1288826.MSNKSG1_11003 1.99e-32 116.0 COG2846@1|root,COG2846@2|Bacteria 2|Bacteria D Di-iron-containing protein involved in the repair of iron-sulfur clusters ytfE GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564 - ko:K07322 - - - - ko00000 - - iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820 Hemerythrin,ScdA_N k141_5252_3 1288826.MSNKSG1_10998 9.42e-244 685.0 COG5001@1|root,COG5001@2|Bacteria 2|Bacteria T cyclic-guanylate-specific phosphodiesterase activity - - - - - - - - - - - - EAL,GGDEF,Hemerythrin,PAS_3,PAS_9 k141_5252_4 1288826.MSNKSG1_10993 2.94e-99 290.0 COG3154@1|root,COG3154@2|Bacteria,1N6DG@1224|Proteobacteria,1SA52@1236|Gammaproteobacteria,4691B@72275|Alteromonadaceae 1236|Gammaproteobacteria I SCP-2 sterol transfer family - - - - - - - - - - - - SCP2 k141_17082_1 525257.HMPREF0204_10347 2.25e-30 132.0 COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia,3ZNM7@59732|Chryseobacterium 976|Bacteroidetes M RHS repeat-associated core domain protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_14279_1 522373.Smlt3967 2.3e-56 189.0 COG1307@1|root,COG1307@2|Bacteria,1R5M9@1224|Proteobacteria,1RZYN@1236|Gammaproteobacteria,1XCQP@135614|Xanthomonadales 135614|Xanthomonadales S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV k141_13626_1 1198232.CYCME_1118 7.82e-152 436.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,45ZR9@72273|Thiotrichales 72273|Thiotrichales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_19243_1 999550.KI421507_gene2359 1.92e-58 193.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_10115_1 395493.BegalDRAFT_0738 2.69e-60 200.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales 72273|Thiotrichales T response regulator receiver - - - - - - - - - - - - DUF229,HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_12957_1 32049.SYNPCC7002_A0847 1.91e-18 84.0 COG0451@1|root,COG0451@2|Bacteria,1G0TM@1117|Cyanobacteria,1GZ9Q@1129|Synechococcus 1117|Cyanobacteria GM Sulfolipid (UDP-sulfoquinovose) biosynthesis protein sqdB - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k141_12957_2 639030.JHVA01000001_gene3250 1.13e-09 62.4 COG1215@1|root,COG1215@2|Bacteria,3Y5DJ@57723|Acidobacteria,2JJU5@204432|Acidobacteriia 204432|Acidobacteriia M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_6608_1 467661.RKLH11_3174 2.83e-116 344.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2TUJV@28211|Alphaproteobacteria,3ZHZD@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_8114_2 1122194.AUHU01000007_gene228 5.93e-28 109.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,467V4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA k141_8114_3 498211.CJA_2804 4.03e-117 342.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1FG79@10|Cellvibrio 1236|Gammaproteobacteria S Branched-chain amino acid ATP-binding cassette transporter lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_8114_4 283942.IL0396 1.28e-35 137.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,2QFAU@267893|Idiomarinaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_16369_1 265072.Mfla_0175 1.07e-62 201.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WFS6@28216|Betaproteobacteria,2KN7H@206350|Nitrosomonadales 206350|Nitrosomonadales S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_12258_1 1237149.C900_01044 6.91e-14 65.5 COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,47S5W@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_12258_2 1237149.C900_01043 1.97e-85 253.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,47P74@768503|Cytophagia 976|Bacteroidetes J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_2454_1 1288826.MSNKSG1_06348 1.17e-142 416.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,465NM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0155 Sulfite reductase, beta subunit (hemoprotein) cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_5253_2 1049564.TevJSym_ap00670 3.06e-30 114.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1J4XT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_15740_1 1278309.KB907099_gene2793 1.65e-174 492.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,1XP1R@135619|Oceanospirillales 135619|Oceanospirillales F Choline/ethanolamine kinase - - - - - - - - - - - - APH k141_15740_2 1278309.KB907099_gene2794 1.62e-58 189.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XHPM@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_1796_1 1288298.rosmuc_03088 2.01e-117 352.0 COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,46PSW@74030|Roseovarius 28211|Alphaproteobacteria C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit nuoEF - 1.17.1.9 ko:K00122 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB k141_21322_1 1278309.KB907099_gene2644 8.23e-236 656.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RN4R@1236|Gammaproteobacteria,1XIVG@135619|Oceanospirillales 135619|Oceanospirillales C Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM k141_21322_2 1278309.KB907099_gene2643 1.01e-287 797.0 COG2010@1|root,COG2010@2|Bacteria,1MUF6@1224|Proteobacteria,1RZFE@1236|Gammaproteobacteria,1XIPJ@135619|Oceanospirillales 135619|Oceanospirillales C Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - - - - - - - - - - Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV k141_21322_3 1278309.KB907099_gene2642 2.49e-146 415.0 COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XR8H@135619|Oceanospirillales 135619|Oceanospirillales T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_21322_4 1278309.KB907099_gene2641 0.0 1398.0 COG0515@1|root,COG0642@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1T55X@1236|Gammaproteobacteria,1XI8Z@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg k141_1083_1 1121035.AUCH01000009_gene884 4e-85 265.0 COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,2VMJE@28216|Betaproteobacteria,2KVTK@206389|Rhodocyclales 206389|Rhodocyclales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_1083_2 1283300.ATXB01000001_gene428 1.32e-78 241.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1XFWX@135618|Methylococcales 135618|Methylococcales S VIT family - - - - - - - - - - - - VIT1 k141_20624_1 998674.ATTE01000001_gene2452 1.37e-96 290.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,460VC@72273|Thiotrichales 72273|Thiotrichales C oxidase subunit III cyoC - 1.9.3.1 ko:K02164,ko:K02276,ko:K02299 ko00190,ko01100,map00190,map01100 M00155,M00417 R00081,R00294 RC00016,RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10,3.D.4.4,3.D.4.5,3.D.4.6 - - COX3 k141_20624_2 323261.Noc_3045 7.76e-52 173.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,1X0T0@135613|Chromatiales 135613|Chromatiales O PFAM Cytochrome c oxidase assembly protein CtaG Cox11 - - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_20624_3 1469245.JFBG01000016_gene967 3.75e-83 261.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1WWX1@135613|Chromatiales 135613|Chromatiales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_8725_2 1333998.M2A_0852 1.59e-53 178.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2TS1B@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase gstch1 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_12259_1 1121939.L861_01290 3.74e-58 197.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1XHDV@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_7343_1 582744.Msip34_1552 1.43e-97 287.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KM7B@206350|Nitrosomonadales 206350|Nitrosomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_17818_1 1278309.KB907106_gene1375 3.75e-230 637.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XH84@135619|Oceanospirillales 135619|Oceanospirillales E D-amino acid - - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_8116_1 1294273.roselon_02713 1.32e-09 57.0 2E8MM@1|root,332Z2@2|Bacteria,1N74Q@1224|Proteobacteria,2UFS8@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_8116_2 367336.OM2255_03750 1.41e-39 142.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases dapE_1 - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_17084_1 767434.Fraau_0411 1.06e-103 304.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1X3QU@135614|Xanthomonadales 135614|Xanthomonadales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_10116_1 1163617.SCD_n01691 1.88e-13 69.3 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria 28216|Betaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_10116_2 1415778.JQMM01000001_gene2182 1.02e-92 283.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP synthase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_14999_2 225937.HP15_2652 2.2e-94 285.0 COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,466HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P ZIP Zinc transporter zupT GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - iECIAI39_1322.ECIAI39_3536 Zip k141_15741_1 1342302.JASC01000013_gene3112 2.18e-07 51.6 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,3ZWIY@60136|Sulfitobacter 28211|Alphaproteobacteria S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DUF3394,DctM k141_15741_2 391624.OIHEL45_06415 1.08e-56 180.0 COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,2UABJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins MA20_08295 - - - - - - - - - - - Usp k141_15741_3 1342301.JASD01000008_gene1422 2.83e-07 50.8 COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,2TTKF@28211|Alphaproteobacteria,3ZVDV@60136|Sulfitobacter 28211|Alphaproteobacteria S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase k141_4579_1 520709.F985_00661 3.75e-59 197.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1SAC7@1236|Gammaproteobacteria 1236|Gammaproteobacteria H SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - Radical_SAM k141_20625_1 1342302.JASC01000014_gene2131 1.26e-74 233.0 COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,3ZW8N@60136|Sulfitobacter 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA,Multi_Drug_Res k141_19245_1 59374.Fisuc_2183 2.46e-24 100.0 2DC00@1|root,2ZC4V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_4600_2 857087.Metme_1847 2.51e-66 210.0 COG2095@1|root,COG2095@2|Bacteria,1MV1C@1224|Proteobacteria,1RPM8@1236|Gammaproteobacteria,1XGYB@135618|Methylococcales 135618|Methylococcales U PFAM Multiple antibiotic resistance (MarC)-related - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_10880_1 1288826.MSNKSG1_11278 1.88e-291 798.0 28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,4683V@72275|Alteromonadaceae 1236|Gammaproteobacteria S F plasmid transfer operon, TraF, protein traF - - - - - - - - - - - TraF_2 k141_10880_2 1288826.MSNKSG1_11283 2.58e-238 659.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,4641Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca GO:0001680,GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016437,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042245,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_10880_3 1288826.MSNKSG1_11288 4.01e-181 503.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,466CG@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ycdF - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_10880_4 1288826.MSNKSG1_11293 1.6e-29 114.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family phbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_16394_1 1042375.AFPL01000038_gene1609 4.51e-105 313.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,1RMG8@1236|Gammaproteobacteria,469TC@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - 1.14.14.12 ko:K16047 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R09819 RC00236 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_16394_2 159087.Daro_0903 2.38e-100 294.0 COG1853@1|root,COG1853@2|Bacteria,1MZKY@1224|Proteobacteria,2VVEB@28216|Betaproteobacteria,2KZAZ@206389|Rhodocyclales 206389|Rhodocyclales S Flavin reductase like domain - - 1.5.1.36 ko:K00484 ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220 - R02698,R03299,R05705,R09748,R09750 RC00046,RC00126 ko00000,ko00001,ko01000 - - - Flavin_Reduct k141_16394_3 1265490.JHVY01000006_gene1978 1.71e-158 449.0 COG2021@1|root,COG2021@2|Bacteria,1QVFH@1224|Proteobacteria,1T2DF@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid mhpC - 3.7.1.14 ko:K05714 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R02603,R06789 RC00752,RC00753,RC01337 br01602,ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 k141_16394_4 1042375.AFPL01000038_gene1611 3.46e-114 335.0 COG1414@1|root,COG1414@2|Bacteria,1QRZN@1224|Proteobacteria,1RYF9@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator mhpR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K05818 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_16394_6 440512.C211_08569 2.42e-36 130.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q hydratase mhpD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0008150,GO:0008152,GO:0008684,GO:0009056,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914 4.2.1.80 ko:K02554 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R02601,R04781 RC00750,RC01213 br01602,ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0386,iECO26_1355.ECO26_0386,iECW_1372.ECW_m0428,iEKO11_1354.EKO11_3492,iEcE24377_1341.EcE24377A_0374,iEcHS_1320.EcHS_A0414,iWFL_1372.ECW_m0428 FAA_hydrolase k141_14297_1 314271.RB2654_14690 7.96e-37 137.0 COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade - 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_14297_2 501479.ACNW01000099_gene991 5.82e-32 115.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Ubiquinol-cytochrome C reductase MA20_25125 - - - - - - - - - - - EVE k141_8138_1 1348635.BBJY01000003_gene3933 5.2e-17 79.7 COG2199@1|root,COG2199@2|Bacteria,1R4XN@1224|Proteobacteria,1RQ6S@1236|Gammaproteobacteria,1XTYC@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_22018_1 765911.Thivi_3391 8.82e-38 140.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1WXAZ@135613|Chromatiales 135613|Chromatiales T EAL domain - - - - - - - - - - - - EAL,HDOD k141_17842_1 911239.CF149_06904 2.02e-61 210.0 COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1N2CB@1224|Proteobacteria 1224|Proteobacteria L ATP-dependent endonuclease of the OLD family - - - ko:K07459 - - - - ko00000 - - - AAA_15 k141_5282_1 1163617.SCD_n00315 1.58e-73 237.0 COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - k141_15758_1 1165096.ARWF01000001_gene691 1.73e-31 110.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,2KN9E@206350|Nitrosomonadales 206350|Nitrosomonadales S Iron-sulphur cluster assembly - - - - - - - - - - - - Fe-S_assembly k141_15758_2 748658.KB907314_gene142 4.23e-51 163.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1X16T@135613|Chromatiales 135613|Chromatiales C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K04755 - - - - ko00000 - - - Fer2 k141_15758_3 1268239.PALB_19240 7.79e-09 56.2 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,2Q0N7@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_18506_1 1382359.JIAL01000001_gene1984 1.67e-63 213.0 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity - - - - - - - - - - - - CCP_MauG k141_17102_1 1178482.BJB45_09435 1.02e-75 237.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XIVQ@135619|Oceanospirillales 135619|Oceanospirillales C Aldo keto reductase tas - - - - - - - - - - - Aldo_ket_red k141_17102_2 768066.HELO_3491 1.37e-45 150.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XK38@135619|Oceanospirillales 135619|Oceanospirillales FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hinT - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_8742_1 1049564.TevJSym_an00030 6.47e-131 389.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7AF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F 5'-nucleotidase, C-terminal domain soxB - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C k141_20637_1 439235.Dalk_4509 8.81e-09 56.2 COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,434AT@68525|delta/epsilon subdivisions,2X9GM@28221|Deltaproteobacteria,2MNQ4@213118|Desulfobacterales 28221|Deltaproteobacteria L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_15023_3 1313421.JHBV01000027_gene1835 5.69e-07 51.6 COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,1IXQF@117747|Sphingobacteriia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_13651_1 1278309.KB907101_gene642 1.35e-123 384.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XI5I@135619|Oceanospirillales 135619|Oceanospirillales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_7362_1 1056820.KB900663_gene3760 2.83e-14 72.8 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,2PNAW@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS,PAS_4 k141_7362_2 945543.VIBR0546_13975 1.85e-49 165.0 COG1335@1|root,COG1335@2|Bacteria,1REQ3@1224|Proteobacteria,1SAXP@1236|Gammaproteobacteria,1XWGQ@135623|Vibrionales 135623|Vibrionales Q COG1335 Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_12980_1 1173027.Mic7113_0539 9.58e-32 128.0 COG0531@1|root,COG0531@2|Bacteria,1G2VF@1117|Cyanobacteria,1HH8S@1150|Oscillatoriales 1117|Cyanobacteria E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k141_22148_2 1286106.MPL1_05247 3.25e-31 114.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,460ZK@72273|Thiotrichales 72273|Thiotrichales J Belongs to the HSP15 family - - - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_1944_3 1294143.H681_25040 3.17e-58 183.0 COG3865@1|root,COG3865@2|Bacteria,1MZHY@1224|Proteobacteria 1224|Proteobacteria S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt k141_1944_4 1298863.AUEP01000010_gene4477 5.8e-27 103.0 2DNU1@1|root,32Z4S@2|Bacteria,2INE9@201174|Actinobacteria 201174|Actinobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_11031_1 472759.Nhal_1173 1.81e-74 226.0 COG2062@1|root,COG2062@2|Bacteria,1RGWQ@1224|Proteobacteria,1S9W7@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine phosphatase superfamily (branch 1) sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_11031_2 261292.Nit79A3_2054 1.16e-139 409.0 COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales 28216|Betaproteobacteria KT PFAM Metal-dependent phosphohydrolase, HD - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,GAF_2,HD k141_15894_1 1005048.CFU_0894 6.13e-58 196.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIJX@28216|Betaproteobacteria,475ME@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ AMP-binding enzyme C-terminal domain matB - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_15894_2 1236959.BAMT01000004_gene968 3.37e-100 313.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria,2KNQG@206350|Nitrosomonadales 206350|Nitrosomonadales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_15894_3 675814.VIC_001122 1.37e-13 71.2 COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria,1XUCJ@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain rstA - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_11695_2 1122197.ATWI01000013_gene2352 7.4e-87 256.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,466UW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L17 rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_13147_1 1123368.AUIS01000013_gene852 1.93e-42 153.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,2NCB0@225057|Acidithiobacillales 1236|Gammaproteobacteria G Protein of unknown function (DUF3417) - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_13147_2 857087.Metme_0076 8.26e-37 127.0 COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,1SC8R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_12466_1 545264.KB898745_gene1036 3.24e-30 117.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T1Q9@1236|Gammaproteobacteria,1WZXW@135613|Chromatiales 135613|Chromatiales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_12466_2 1158762.KB898040_gene1552 5.15e-42 149.0 COG2430@1|root,COG2430@2|Bacteria,1N0R1@1224|Proteobacteria,1SQ9A@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6759_1 913325.N799_14260 8.39e-59 206.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1X4J8@135614|Xanthomonadales 135614|Xanthomonadales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_15913_1 675817.VDA_000885 9.74e-55 191.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XTY1@135623|Vibrionales 135623|Vibrionales V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain lapB - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_7527_2 765911.Thivi_3295 3.66e-61 204.0 COG2304@1|root,COG2304@2|Bacteria,1RIUR@1224|Proteobacteria 1224|Proteobacteria S von Willebrand factor type A domain - - - - - - - - - - - - VWA,VWA_2 k141_8860_1 1380390.JIAT01000010_gene3743 4.38e-27 114.0 COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4CPUW@84995|Rubrobacteria 84995|Rubrobacteria M NlpC/P60 family - - - ko:K21473 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k141_19393_2 395493.BegalDRAFT_1304 8.13e-121 352.0 COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,1RNZ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM beta-lactamase domain protein - - - - - - - - - - - - Lactamase_B k141_9541_1 1288826.MSNKSG1_00071 9.59e-136 384.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,466WU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_8279_1 713586.KB900536_gene785 1.57e-76 247.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_8279_2 1049564.TevJSym_bm00140 3.8e-54 176.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1J656@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325 CDP-OH_P_transf k141_2619_1 713586.KB900536_gene1464 4.1e-134 400.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,1X2J4@135613|Chromatiales 135613|Chromatiales T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_12467_1 633131.TR2A62_2564 1.85e-89 273.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_18687_2 1217718.ALOU01000019_gene2692 1.91e-31 114.0 COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2VTXS@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III nirC - - ko:K19344 - - - - ko00000 - - - Cytochrome_CBB3 k141_18687_3 1333856.L686_22505 1.04e-60 198.0 COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,1RYUT@1236|Gammaproteobacteria,1Z0FQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Heme d1 biosynthesis protein NirF nirF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K19345 - - - - ko00000 - - - Cytochrom_D1 k141_1293_1 1232683.ADIMK_4111 2.7e-13 69.3 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA k141_1293_2 1232683.ADIMK_4110 3.55e-31 119.0 COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,1SBTI@1236|Gammaproteobacteria,46BV1@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp k141_17268_1 1278309.KB907106_gene1360 4.56e-292 820.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XHN6@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_17268_2 1278309.KB907106_gene1361 3.88e-99 289.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XK4C@135619|Oceanospirillales 135619|Oceanospirillales MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_1954_1 421052.F945_00669 1.36e-46 168.0 COG4421@1|root,COG4421@2|Bacteria,1NH8W@1224|Proteobacteria,1TMRA@1236|Gammaproteobacteria,3NP7B@468|Moraxellaceae 1236|Gammaproteobacteria G Protein of unknown function (DUF563) - - - - - - - - - - - - DUF563 k141_1954_2 1280692.AUJL01000001_gene312 2.54e-05 51.6 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,24N29@186801|Clostridia,36UWS@31979|Clostridiaceae 186801|Clostridia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_22171_1 420662.Mpe_A3227 6.18e-20 86.3 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,1KJEQ@119065|unclassified Burkholderiales 28216|Betaproteobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_22171_2 1198232.CYCME_0725 1.1e-36 131.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,460JE@72273|Thiotrichales 72273|Thiotrichales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_3988_1 314270.RB2083_1448 9.08e-96 288.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TVBH@28211|Alphaproteobacteria,3ZHJD@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria P COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components mglC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440,ko:K17214 ko02010,map02010 M00212,M00593 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_5469_2 379731.PST_0206 1.87e-71 221.0 COG1573@1|root,COG1573@2|Bacteria,1RBR1@1224|Proteobacteria,1RZ8U@1236|Gammaproteobacteria,1Z08N@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L uracil-DNA glycosylase - - - - - - - - - - - - UDG k141_11696_1 411154.GFO_0031 3.26e-111 345.0 COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_6099_1 243160.BMAA2111 1.08e-15 75.9 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,1K198@119060|Burkholderiaceae 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_6099_2 2340.JV46_08740 1.95e-301 833.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1J4JD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the glutamate synthase family gltB - - - - - - - - - - - Glu_synthase k141_16560_1 1278309.KB907100_gene1857 0.0 1144.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XHWN@135619|Oceanospirillales 135619|Oceanospirillales J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_11042_1 207954.MED92_08101 2.01e-119 353.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1XHDS@135619|Oceanospirillales 135619|Oceanospirillales K RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_11042_2 207954.MED92_08096 5.74e-47 160.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XJ9X@135619|Oceanospirillales 135619|Oceanospirillales DM COG0739 Membrane proteins related to metalloendopeptidases nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_12468_1 313606.M23134_04235 3.49e-102 309.0 COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 k141_1294_1 1123073.KB899241_gene2360 1.06e-55 188.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X3EN@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the peptidase S1C family htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_22172_1 395493.BegalDRAFT_3522 2.03e-81 258.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,45ZTY@72273|Thiotrichales 72273|Thiotrichales HJ Glutathione synthase Ribosomal protein S6 modification enzyme - - - - - - - - - - - - RLAN,RimK k141_15915_1 1207076.ALAT01000147_gene293 2.43e-99 304.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1Z11J@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_10317_1 207954.MED92_07611 6.56e-199 572.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1XI8F@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - CBS,EAL,GGDEF k141_10317_2 1278309.KB907100_gene1892 1.28e-86 259.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XK4I@135619|Oceanospirillales 135619|Oceanospirillales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_7529_1 1437448.AZRT01000014_gene1751 2.97e-45 154.0 COG3613@1|root,COG4271@1|root,COG3613@2|Bacteria,COG4271@2|Bacteria,1RFT4@1224|Proteobacteria,2UA59@28211|Alphaproteobacteria 28211|Alphaproteobacteria F DNA primase activity - - - - - - - - - - - - - k141_7529_2 1094715.CM001373_gene2147 1.13e-82 252.0 2APRZ@1|root,31EVU@2|Bacteria,1QC87@1224|Proteobacteria,1T7XK@1236|Gammaproteobacteria,1JFZZ@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - k141_9542_3 1120956.JHZK01000015_gene3001 1.11e-23 96.7 COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria,2TVXW@28211|Alphaproteobacteria,1JP0A@119043|Rhodobiaceae 28211|Alphaproteobacteria T cheY-homologous receiver domain divK - - ko:K11443 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg k141_11697_1 292415.Tbd_1413 3.91e-86 259.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,1KRJK@119069|Hydrogenophilales 119069|Hydrogenophilales V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_12469_1 395493.BegalDRAFT_0735 5.59e-63 201.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,462B7@72273|Thiotrichales 72273|Thiotrichales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - - - - - - - - - - CcmB k141_6762_2 1005994.GTGU_02274 8.96e-25 100.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria 1236|Gammaproteobacteria O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479 ABC_tran k141_17270_1 566466.NOR53_218 8.22e-39 130.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1J6B1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_17270_2 1234364.AMSF01000027_gene3528 1.09e-58 183.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1X722@135614|Xanthomonadales 135614|Xanthomonadales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_17270_3 767434.Fraau_0664 1.78e-41 142.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1X304@135614|Xanthomonadales 135614|Xanthomonadales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_11044_1 1307759.JOMJ01000004_gene2521 2.32e-24 107.0 COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2MAB3@213115|Desulfovibrionales 28221|Deltaproteobacteria T ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein - - - - - - - - - - - - HATPase_c,HDOD,HisKA,Response_reg k141_2621_1 1283300.ATXB01000001_gene253 1.6e-35 130.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XEN4@135618|Methylococcales 135618|Methylococcales M Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_2621_2 1116472.MGMO_37c00170 1.87e-101 303.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XDWR@135618|Methylococcales 135618|Methylococcales D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_13150_1 105559.Nwat_2391 1.2e-07 51.6 2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,1SGHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K06950 - - - - ko00000 - - - - k141_13150_2 1049564.TevJSym_ai00270 1.49e-06 53.1 COG4969@1|root,COG4969@2|Bacteria 2|Bacteria NU cell adhesion pilA - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_10318_2 1137799.GZ78_23280 1.05e-23 101.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,1XM2S@135619|Oceanospirillales 135619|Oceanospirillales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_9543_1 1121935.AQXX01000122_gene5647 4.14e-61 202.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1XJ4H@135619|Oceanospirillales 135619|Oceanospirillales E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_1296_1 1288826.MSNKSG1_10713 1.69e-143 423.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_7530_2 314345.SPV1_06149 9.88e-127 365.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria 1224|Proteobacteria F Creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_17271_1 1196835.A458_07765 4.01e-73 227.0 28PV8@1|root,2ZCFZ@2|Bacteria,1RBCG@1224|Proteobacteria,1SNPA@1236|Gammaproteobacteria,1Z23H@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16561_2 1218075.BAYA01000007_gene2722 3.22e-66 205.0 2C5J1@1|root,3067M@2|Bacteria,1N4SF@1224|Proteobacteria,2VWDM@28216|Betaproteobacteria,1K9HT@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_16561_3 596154.Alide2_1079 2.32e-43 157.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VJD3@28216|Betaproteobacteria,4AC9E@80864|Comamonadaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k141_6100_1 396588.Tgr7_3255 5.93e-268 757.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales 135613|Chromatiales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_8280_1 1278309.KB907108_gene1549 1.68e-96 338.0 COG0771@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4347 k141_13151_1 1123247.AUIJ01000045_gene201 7.31e-131 393.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs coxL - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_20737_1 697282.Mettu_3311 9.02e-28 113.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XDT6@135618|Methylococcales 135618|Methylococcales P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_20737_2 1247726.MIM_c05260 7e-12 70.1 COG5589@1|root,COG5589@2|Bacteria,1N6W5@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 k141_20737_3 592028.GCWU000321_00147 1.25e-13 73.2 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H3NI@909932|Negativicutes 909932|Negativicutes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - AI-2E_transport k141_11045_1 1188256.BASI01000001_gene275 1.99e-25 100.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,3FD3Z@34008|Rhodovulum 28211|Alphaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_11045_2 367336.OM2255_10361 1.03e-36 125.0 COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_11045_3 367336.OM2255_10366 2.7e-37 130.0 COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF2 - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_12571_1 697282.Mettu_3162 9.38e-33 133.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_21625_2 1278309.KB907106_gene1338 9.37e-230 634.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_21625_3 1278309.KB907106_gene1337 1.06e-137 390.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1XI4I@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_13269_1 1123054.KB907717_gene211 5.94e-48 157.0 COG2105@1|root,COG2105@2|Bacteria,1NBAY@1224|Proteobacteria,1SCTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT k141_13269_2 1168065.DOK_17865 2.87e-143 407.0 COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,1T268@1236|Gammaproteobacteria,1J83V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0421 Spermidine synthase - - - - - - - - - - - - - k141_13269_4 1278309.KB907099_gene2612 2.73e-84 248.0 COG3450@1|root,COG3450@2|Bacteria,1REFN@1224|Proteobacteria,1S4J1@1236|Gammaproteobacteria,1XKBB@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF861) - - - ko:K06995 - - - - ko00000 - - - Cupin_3 k141_13269_5 1232683.ADIMK_3864 2.3e-78 240.0 COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria,466TI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Lysine exporter protein (LysE YggA) - - - ko:K05834 - - - - ko00000,ko02000 2.A.76.1.1 - - LysE k141_13269_6 1232683.ADIMK_3863 5.48e-292 803.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,464EG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2252 Permeases pbuO - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_13269_7 1232683.ADIMK_3862 3.81e-126 363.0 COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,1RS75@1236|Gammaproteobacteria,467G6@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD HA62_00785 - - - - - - - - - - - FCD,GntR k141_15358_1 43989.cce_2032 2.63e-12 76.6 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGMH@43988|Cyanothece 1117|Cyanobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_16_1 1122135.KB893171_gene2014 4.89e-65 211.0 COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,2TUC6@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_4896_1 1288826.MSNKSG1_12062 1.9e-43 146.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,4689F@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_4896_2 1288826.MSNKSG1_12067 0.0 1075.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,463Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - iYL1228.KPN_04331 ABC1 k141_4896_3 1288826.MSNKSG1_12072 2.09e-98 285.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4679A@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH k141_4896_4 1288826.MSNKSG1_12077 1.48e-31 112.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,467UR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0140 Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_722_1 1535422.ND16A_1869 1e-44 152.0 COG0500@1|root,COG0500@2|Bacteria,1R5D7@1224|Proteobacteria,1TFEU@1236|Gammaproteobacteria,2Q8EV@267889|Colwelliaceae 1236|Gammaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_18136_1 1278309.KB907100_gene2231 3.84e-278 779.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_18136_2 1424334.W822_03455 1.78e-28 108.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,3T4KJ@506|Alcaligenaceae 28216|Betaproteobacteria K transcriptional cueR - - ko:K19591,ko:K19592 - M00768,M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind k141_18136_3 1278309.KB907100_gene2228 2.06e-88 261.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1XKTR@135619|Oceanospirillales 135619|Oceanospirillales S metal-binding protein - - - - - - - - - - - - DUF411 k141_18136_4 1278309.KB907100_gene2227 9.86e-80 238.0 COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,1S976@1236|Gammaproteobacteria,1XKK4@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_20238_1 1026882.MAMP_01683 3.7e-44 152.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,45ZNV@72273|Thiotrichales 72273|Thiotrichales D PFAM CobQ CobB MinD ParA nucleotide binding domain parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,MipZ k141_20238_3 448385.sce6427 3.44e-20 94.0 COG0515@1|root,COG2267@1|root,COG0515@2|Bacteria,COG2267@2|Bacteria,1PEH3@1224|Proteobacteria,430NV@68525|delta/epsilon subdivisions,2WW17@28221|Deltaproteobacteria,2YTSZ@29|Myxococcales 28221|Deltaproteobacteria KLT serine threonine protein kinase - - - - - - - - - - - - FGE-sulfatase,Pkinase k141_11177_2 243277.VC_A0346 1.97e-55 179.0 2F2SR@1|root,33VNZ@2|Bacteria,1NW6D@1224|Proteobacteria,1SPM2@1236|Gammaproteobacteria,1Y18W@135623|Vibrionales 135623|Vibrionales S Lecithin retinol acyltransferase - - - - - - - - - - - - LRAT k141_7693_2 1386089.N865_20505 7.71e-86 262.0 COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria 201174|Actinobacteria G Belongs to the HAD-like hydrolase superfamily - - - ko:K02566 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like k141_3503_1 1232683.ADIMK_0257 6.47e-118 360.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,465N7@72275|Alteromonadaceae 1236|Gammaproteobacteria S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_14664_1 1499686.BN1079_01446 6.34e-65 226.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_11873_1 83219.PM02_07685 3.97e-42 143.0 COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,3ZX75@60136|Sulfitobacter 28211|Alphaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. msrC - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 k141_18843_1 102129.Lepto7375DRAFT_7500 8.19e-17 87.8 COG0358@1|root,COG0553@1|root,COG0358@2|Bacteria,COG0553@2|Bacteria,1G4K0@1117|Cyanobacteria,1HF6S@1150|Oscillatoriales 1117|Cyanobacteria KL C-terminal domain on Strawberry notch homologue - - - - - - - - - - - - AAA_34,Helicase_C_4,MutS_I k141_4198_1 216595.PFLU_5924 8.23e-07 50.4 COG0668@1|root,COG0668@2|Bacteria,1RCM8@1224|Proteobacteria,1SCM2@1236|Gammaproteobacteria,1YMQ5@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_4198_2 391615.ABSJ01000017_gene1628 1.57e-49 172.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1J571@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_2110_1 400668.Mmwyl1_1218 5.65e-66 218.0 2AXBE@1|root,31PAH@2|Bacteria,1RJC8@1224|Proteobacteria,1S7IN@1236|Gammaproteobacteria,1XQ0Y@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_2110_3 1278309.KB907109_gene3288 2.55e-288 790.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XHJ0@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - tRNA-synt_1b k141_2110_4 1278309.KB907109_gene3287 1.35e-238 667.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XHD2@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase M23 - - - - - - - - - - - - OapA,Peptidase_M23 k141_2110_5 1278309.KB907109_gene3286 2.67e-204 572.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1XH7D@135619|Oceanospirillales 135619|Oceanospirillales O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_13270_1 1278309.KB907099_gene2497 9.54e-69 211.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XK9Y@135619|Oceanospirillales 135619|Oceanospirillales M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03767 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_13270_2 1278309.KB907099_gene2498 2.24e-77 236.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S5VC@1236|Gammaproteobacteria,1XS69@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 k141_7715_1 1288826.MSNKSG1_08673 3.37e-146 428.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_11208_1 1219375.CM002139_gene1051 1.8e-86 265.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales 135614|Xanthomonadales G 6-phosphogluconate dehydrogenase gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_21644_1 1278309.KB907106_gene1221 7.03e-32 118.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XHKY@135619|Oceanospirillales 135619|Oceanospirillales P Formate/nitrite transporter - - - - - - - - - - - - Form_Nir_trans k141_21644_2 1278309.KB907106_gene1222 1.37e-149 438.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XH4V@135619|Oceanospirillales 135619|Oceanospirillales KLT Serine Threonine protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_15382_1 370438.PTH_2315 4.78e-32 123.0 COG0739@1|root,COG0739@2|Bacteria,1UYKB@1239|Firmicutes,25B2K@186801|Clostridia 186801|Clostridia M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_12594_1 351016.RAZWK3B_05747 5.34e-39 150.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,2P3KE@2433|Roseobacter 28211|Alphaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_7019_1 90814.KL370891_gene438 1.28e-30 121.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,460N2@72273|Thiotrichales 72273|Thiotrichales S Permease YjgP YjgQ lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_5618_1 91464.S7335_427 3.77e-54 187.0 COG0596@1|root,COG0596@2|Bacteria,1GQGS@1117|Cyanobacteria,1H229@1129|Synechococcus 1117|Cyanobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_6 k141_5618_3 493475.GARC_1242 2.26e-18 88.6 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_5618_4 1121403.AUCV01000012_gene4046 1.45e-23 95.9 COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,43B7J@68525|delta/epsilon subdivisions,2X6KZ@28221|Deltaproteobacteria,2MMAU@213118|Desulfobacterales 28221|Deltaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_20965_1 1238190.AMQY01000010_gene2305 1.34e-73 235.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,1XN9D@135619|Oceanospirillales 135619|Oceanospirillales L COG5377 Phage-related protein - - - - - - - - - - - - YqaJ k141_15383_1 42565.FP66_01330 2.8e-103 310.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XIK3@135619|Oceanospirillales 135619|Oceanospirillales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_14688_1 1278309.KB907099_gene2843 2.39e-297 849.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XHUD@135619|Oceanospirillales 135619|Oceanospirillales L Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_12595_1 247639.MGP2080_14329 6.57e-25 100.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1J4PE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_12595_2 1260251.SPISAL_02945 5.67e-10 58.5 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales 135613|Chromatiales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_10493_1 1395571.TMS3_0115105 3.74e-71 234.0 COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,1RP39@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_10493_2 1049564.TevJSym_bk00180 4.69e-51 168.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1J4G1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 k141_21645_1 195105.CN97_20175 3.57e-32 122.0 COG3203@1|root,COG3203@2|Bacteria,1MX5Q@1224|Proteobacteria,2UA49@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Gram-negative porin - - - ko:K08720 ko01501,ko05111,map01501,map05111 - - - ko00000,ko00001,ko02000 1.B.1.2.1 - - Porin_4 k141_5619_1 930166.CD58_17315 4.75e-55 188.0 COG0654@1|root,COG0654@2|Bacteria,1MX9R@1224|Proteobacteria,1SYDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) - - 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_5619_2 1168059.KB899087_gene3633 3.69e-05 46.2 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family gabD6 - - ko:K15786 ko00260,map00260 - R09805 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_9796_2 1121015.N789_12395 1.35e-79 249.0 COG1638@1|root,COG1638@2|Bacteria,1PBU6@1224|Proteobacteria,1RXK0@1236|Gammaproteobacteria,1X5NG@135614|Xanthomonadales 135614|Xanthomonadales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_15384_1 1178482.BJB45_02540 2.09e-24 107.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XISY@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,dCache_3 k141_14689_1 1237149.C900_05507 8.36e-73 246.0 COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia 976|Bacteroidetes L Superfamily I DNA and RNA - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 k141_7020_1 1122176.KB903549_gene1226 1.03e-27 119.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y k141_20966_1 247633.GP2143_14726 1.06e-27 104.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1J6UC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_16060_1 1278309.KB907106_gene1283 9.62e-188 530.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales 135619|Oceanospirillales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_16060_2 1278309.KB907106_gene1281 1.01e-202 563.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XI0C@135619|Oceanospirillales 135619|Oceanospirillales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_16060_3 1278309.KB907106_gene1280 2.92e-129 374.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1XKI9@135619|Oceanospirillales 135619|Oceanospirillales H synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_7716_1 1237149.C900_01727 1.5e-59 204.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia 976|Bacteroidetes O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_2 k141_7021_1 1049564.TevJSym_av00160 7.89e-106 322.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_21646_1 1234364.AMSF01000082_gene3014 9.68e-12 63.9 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X30C@135614|Xanthomonadales 135614|Xanthomonadales M NAD dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_21646_2 1234364.AMSF01000082_gene3013 1.37e-24 101.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XCEB@135614|Xanthomonadales 135614|Xanthomonadales E Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - ABC_tran,CBS k141_9797_1 631362.Thi970DRAFT_02219 4.35e-97 302.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_10495_1 1123399.AQVE01000035_gene3163 3.46e-76 240.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,461WN@72273|Thiotrichales 72273|Thiotrichales E PFAM Aminotransferase class I and II - - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_33_1 1123253.AUBD01000010_gene2159 1.57e-16 76.6 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_33_2 1395571.TMS3_0114025 2.09e-76 233.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_4910_1 1232683.ADIMK_4139 1.96e-207 606.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,464EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Putative amidoligase enzyme (DUF2126) IV02_11925 - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core k141_14691_1 388401.RB2150_01809 7.96e-52 183.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,3ZGY2@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_5620_1 1288826.MSNKSG1_16901 9.49e-186 518.0 COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,1RR79@1236|Gammaproteobacteria,469W3@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21645 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_17449_1 754476.Q7A_2557 2.76e-152 442.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,4606I@72273|Thiotrichales 72273|Thiotrichales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_17449_2 1122201.AUAZ01000021_gene3215 7.56e-33 125.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,467Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_17449_3 1049564.TevJSym_ac01900 2e-05 52.4 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1J5PH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_7717_1 391595.RLO149_c023920 2.44e-12 71.6 COG3087@1|root,COG3087@2|Bacteria,1MXII@1224|Proteobacteria,2TTG3@28211|Alphaproteobacteria,2P2PD@2433|Roseobacter 28211|Alphaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR k141_9798_1 1123399.AQVE01000005_gene963 8.76e-16 82.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,461X7@72273|Thiotrichales 72273|Thiotrichales V Protein export membrane protein - - - - - - - - - - - - ACR_tran k141_19557_1 555778.Hneap_1517 1.98e-26 100.0 COG0454@1|root,COG0456@2|Bacteria,1RKJA@1224|Proteobacteria,1T1ZP@1236|Gammaproteobacteria,1X1TJ@135613|Chromatiales 135613|Chromatiales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_131_3 1288826.MSNKSG1_06018 7.64e-203 561.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,465KB@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_7143_2 28532.XP_010536515.1 8.19e-07 56.2 COG0501@1|root,KOG2661@2759|Eukaryota,37KS4@33090|Viridiplantae,3G796@35493|Streptophyta,3HPPR@3699|Brassicales 35493|Streptophyta O Peptidase family M48 - GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006508,GO:0006515,GO:0006807,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0019538,GO:0019866,GO:0023052,GO:0030163,GO:0031090,GO:0031929,GO:0031966,GO:0031967,GO:0031975,GO:0035556,GO:0035694,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48 k141_17592_1 1278309.KB907102_gene267 7.46e-64 200.0 2AH9S@1|root,317JX@2|Bacteria,1RKKP@1224|Proteobacteria,1S7FI@1236|Gammaproteobacteria,1XKWT@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_17592_2 1278309.KB907102_gene268 9.8e-66 201.0 2CGNP@1|root,32S4A@2|Bacteria,1N1J7@1224|Proteobacteria,1SAPA@1236|Gammaproteobacteria,1XM5G@135619|Oceanospirillales 135619|Oceanospirillales S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - k141_17592_3 1278309.KB907102_gene269 1e-78 246.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,1RR20@1236|Gammaproteobacteria,1XHNB@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 k141_19694_1 396588.Tgr7_0300 3.09e-113 345.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_863_1 1278309.KB907109_gene3307 5.01e-21 86.7 COG1999@1|root,COG1999@2|Bacteria,1PC4H@1224|Proteobacteria,1SWXI@1236|Gammaproteobacteria,1XM93@135619|Oceanospirillales 135619|Oceanospirillales S signal sequence binding - - - - - - - - - - - - - k141_863_2 287.DR97_3067 5.49e-24 103.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1YFZU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S SURF1 family surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_863_3 1121943.KB899991_gene2375 4.26e-08 52.4 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SGKJ@1236|Gammaproteobacteria,1XMKI@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 k141_863_4 1278309.KB907109_gene3305 3.47e-189 528.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XI6G@135619|Oceanospirillales 135619|Oceanospirillales C Heme copper-type cytochrome quinol oxidase, subunit 3 coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_863_5 1278309.KB907109_gene3304 2.67e-90 269.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,1XJJ9@135619|Oceanospirillales 135619|Oceanospirillales O oxidase assembly ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_863_6 1278309.KB907109_gene3303 0.0 1029.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XH53@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B coxA - 1.10.3.10,1.9.3.1 ko:K02274,ko:K02298 ko00190,ko01100,map00190,map01100 M00155,M00417 R00081,R11335 RC00016,RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6 - - COX1 k141_863_7 1278309.KB907109_gene3302 2.27e-240 664.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XIU7@135619|Oceanospirillales 135619|Oceanospirillales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_2970_1 472759.Nhal_3897 2.14e-71 231.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales 135613|Chromatiales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_2244_1 243160.BMAA0154 3.71e-34 127.0 COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,2VP4J@28216|Betaproteobacteria,1K64M@119060|Burkholderiaceae 28216|Betaproteobacteria IM Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 k141_19008_1 870187.Thini_2780 1.78e-22 90.1 COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,1S5XB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF2269 k141_19008_2 857087.Metme_4098 5.94e-43 154.0 COG0702@1|root,COG0702@2|Bacteria,1PGNB@1224|Proteobacteria,1RUX3@1236|Gammaproteobacteria,1XFGR@135618|Methylococcales 135618|Methylococcales GM epimerase dehydratase - - - - - - - - - - - - DoxX_3,NAD_binding_10 k141_5780_1 2340.JV46_15500 2.41e-64 198.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1J6HU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P conserved protein involved in intracellular sulfur reduction tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_5780_2 396588.Tgr7_2186 2.46e-184 516.0 COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria,1WWM7@135613|Chromatiales 135613|Chromatiales C reductase, dissimilatory-type beta subunit dsrB - 1.8.99.5 ko:K11181 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_14837_1 2340.JV46_26130 3.02e-99 298.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1SJJV@1236|Gammaproteobacteria,1J77S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Galactose-1-phosphate uridyl transferase, N-terminal domain galT - - - - - - - - - - - DUF4921,GalP_UDP_tr_C,GalP_UDP_transf k141_16899_1 358220.C380_17670 9.54e-12 71.6 2DB8Y@1|root,2Z7TF@2|Bacteria,1NCMY@1224|Proteobacteria,2VXBY@28216|Betaproteobacteria 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2236) - - - - - - - - - - - - DUF2236 k141_10650_2 572477.Alvin_2173 4.85e-83 268.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1WW3V@135613|Chromatiales 135613|Chromatiales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL - 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_9202_1 395493.BegalDRAFT_1723 8.18e-134 400.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E ABC-type oligopeptide transport system, periplasmic component yejA GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_17593_1 999547.KI421500_gene3706 1.56e-119 352.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG2041 Sulfite oxidase and related enzymes - - 1.8.3.1 ko:K00387 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00533 RC00168 ko00000,ko00001,ko01000 - - - Mo-co_dimer,Oxidored_molyb k141_2971_1 713587.THITH_01485 2.78e-35 135.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales 135613|Chromatiales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_11364_1 1307759.JOMJ01000003_gene1974 3.92e-17 84.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2WJXH@28221|Deltaproteobacteria,2M7VU@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM N-acetylneuraminic acid synthase - - - - - - - - - - - - NeuB k141_15545_1 290397.Adeh_2888 1.12e-09 58.9 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_15545_2 290397.Adeh_2887 1.05e-76 236.0 COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,438A3@68525|delta/epsilon subdivisions,2X3JI@28221|Deltaproteobacteria,2YWC0@29|Myxococcales 28221|Deltaproteobacteria C Metallo-beta-lactamase superfamily - - - - - - - - - - - - - k141_21759_1 1288826.MSNKSG1_04636 6.87e-85 252.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,467AH@72275|Alteromonadaceae 1236|Gammaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18 k141_21759_2 1288826.MSNKSG1_04631 0.0 1327.0 COG5322@1|root,COG5322@2|Bacteria,1R60X@1224|Proteobacteria,1SMXH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S oxidoreductase activity - - - - - - - - - - - - Semialdhyde_dh k141_8539_1 1397528.Q671_11755 1.32e-85 263.0 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,1S3HN@1236|Gammaproteobacteria,1XJIE@135619|Oceanospirillales 135619|Oceanospirillales S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_12722_1 1219080.VEZ01S_21_01150 8.16e-36 131.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC2 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_12722_2 1123514.KB905899_gene1275 2.16e-11 63.2 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,463X7@72273|Thiotrichales 72273|Thiotrichales G 6-phosphogluconate dehydrogenase, C-terminal domain - - - - - - - - - - - - 6PGD,NAD_binding_2 k141_21144_1 1123279.ATUS01000001_gene1469 6.2e-64 223.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1J4C5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,Cache_3-Cache_2,Globin,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9 k141_2245_1 317025.Tcr_1261 5.16e-79 241.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales 72273|Thiotrichales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_2245_2 768066.HELO_3751 5.52e-37 137.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1XI53@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_9899_1 314345.SPV1_08281 6.93e-146 439.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria 1224|Proteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_865_1 765912.Thimo_1827 7.89e-84 266.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales 135613|Chromatiales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_7145_1 1111732.AZOD01000007_gene405 3.34e-93 286.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1X3IZ@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_17594_1 1122180.Lokhon_00966 3.09e-21 93.6 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,2P87X@245186|Loktanella 28211|Alphaproteobacteria M Penicillin-binding Protein dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_17594_2 1417296.U879_05640 0.000151 46.6 2C7S8@1|root,32RJQ@2|Bacteria,1N2C7@1224|Proteobacteria,2UBZK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - - k141_6435_1 1042375.AFPL01000012_gene713 1.52e-130 382.0 COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria,469MR@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain fabF2 - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_6435_2 400668.Mmwyl1_3886 1.47e-60 191.0 COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,1S9E9@1236|Gammaproteobacteria,1XMHE@135619|Oceanospirillales 135619|Oceanospirillales I 3-hydroxylacyl-(Acyl carrier protein) dehydratase - - - - - - - - - - - - - k141_6435_3 400668.Mmwyl1_3887 8.2e-141 401.0 COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,1RMCB@1236|Gammaproteobacteria,1XNJ5@135619|Oceanospirillales 135619|Oceanospirillales IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_6435_4 1042375.AFPL01000012_gene716 9.12e-233 647.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RQH7@1236|Gammaproteobacteria,469IK@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain fabF1 - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_6435_5 1236542.BALM01000010_gene3724 1.75e-26 110.0 2D9Q2@1|root,32TTQ@2|Bacteria,1N63Z@1224|Proteobacteria,1S9T5@1236|Gammaproteobacteria,2Q9DT@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6435_6 1117647.M5M_15935 1.26e-70 219.0 2E4XF@1|root,32ZRC@2|Bacteria,1NDIY@1224|Proteobacteria,1SF4R@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6435_7 1278309.KB907099_gene2417 1.71e-164 462.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1XH77@135619|Oceanospirillales 135619|Oceanospirillales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_6435_8 1278309.KB907099_gene2418 5.21e-81 244.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1XJWY@135619|Oceanospirillales 135619|Oceanospirillales S Protein affecting phage T7 exclusion by the F plasmid fxsA - - ko:K07113 - - - - ko00000 - - - FxsA k141_6435_9 1278309.KB907099_gene2419 1.61e-57 179.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XKHD@135619|Oceanospirillales 135619|Oceanospirillales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_5781_1 2340.JV46_10180 2e-26 100.0 2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,1SGKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1566_1 1049564.TevJSym_bk00210 6.53e-40 144.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J4SA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_1566_2 187272.Mlg_1097 7.42e-126 386.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WW1G@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_13434_1 6669.EFX64861 0.000954 45.1 COG2227@1|root,KOG1270@2759|Eukaryota,39T8B@33154|Opisthokonta,3BE5R@33208|Metazoa,3CZ4I@33213|Bilateria,41YJT@6656|Arthropoda 33208|Metazoa H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway - - 2.1.1.114,2.1.1.64 ko:K00591 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R02175,R04711,R07235,R08771,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 k141_13434_2 1117379.BABA_11056 1.98e-25 108.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,1ZD5U@1386|Bacillus 91061|Bacilli M GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GAF_3,GDP_Man_Dehyd k141_21760_1 1485544.JQKP01000010_gene845 4.32e-101 302.0 COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2W6SJ@28216|Betaproteobacteria,44VMA@713636|Nitrosomonadales 28216|Betaproteobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA k141_4363_1 1278309.KB907107_gene1649 5.12e-226 625.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1XI82@135619|Oceanospirillales 135619|Oceanospirillales S phosphotransferase related to Ser Thr protein - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_4363_2 1278309.KB907107_gene1648 6.8e-123 355.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1XJ9Z@135619|Oceanospirillales 135619|Oceanospirillales JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase k141_12022_1 768671.ThimaDRAFT_1999 1.69e-13 67.4 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_12022_2 1335757.SPICUR_02270 1.64e-26 110.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1WX4Z@135613|Chromatiales 135613|Chromatiales S AI-2E family transporter - - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_19697_1 387093.SUN_2361 1.73e-74 238.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2YN29@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria E amino acid carrier protein - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_11365_1 65093.PCC7418_0190 6.19e-63 198.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_866_1 1417296.U879_17290 1.27e-97 307.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_15547_1 595494.Tola_1840 2.19e-60 203.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1Y51D@135624|Aeromonadales 135624|Aeromonadales K Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 - - - ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - GAF,Sigma54_activat k141_2973_1 1237149.C900_04442 5.02e-156 470.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,47JTE@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_16189_2 999549.KI421513_gene3288 4e-08 50.4 2EHRS@1|root,33BHI@2|Bacteria,1NGHV@1224|Proteobacteria,2UK22@28211|Alphaproteobacteria,281WJ@191028|Leisingera 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_16189_3 391589.RGAI101_2637 6.55e-05 44.3 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2P2U0@2433|Roseobacter 28211|Alphaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_14122_1 225937.HP15_1774 1.69e-39 136.0 2CH72@1|root,31GTD@2|Bacteria,1QEGI@1224|Proteobacteria,1TB5S@1236|Gammaproteobacteria,4697T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_14122_2 1288826.MSNKSG1_06243 1.97e-224 623.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,464X8@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - iJN746.PP_2734 CMAS k141_17595_1 1122599.AUGR01000002_gene3285 2.5e-63 211.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1XI65@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_7146_1 754476.Q7A_1015 1.58e-129 382.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,45ZND@72273|Thiotrichales 72273|Thiotrichales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_12724_1 377629.TERTU_1665 2.7e-52 174.0 COG3913@1|root,COG3913@2|Bacteria,1N01G@1224|Proteobacteria,1S6EQ@1236|Gammaproteobacteria,2PPPD@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2094) impM - - ko:K11890 ko02025,map02025 - - - ko00000,ko00001,ko02044 - - - DUF2094 k141_11366_1 1123368.AUIS01000006_gene630 1.53e-12 67.8 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,2NC4S@225057|Acidithiobacillales 225057|Acidithiobacillales M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_21145_2 631362.Thi970DRAFT_03106 2.5e-41 142.0 COG0680@1|root,COG0680@2|Bacteria,1RGFM@1224|Proteobacteria,1S4XN@1236|Gammaproteobacteria,1WY9T@135613|Chromatiales 135613|Chromatiales C PFAM Peptidase A31, hydrogen uptake protein - - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI k141_12043_1 596154.Alide2_2589 2.5e-35 127.0 COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,2VSRU@28216|Betaproteobacteria,4AF9Y@80864|Comamonadaceae 28216|Betaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_2255_1 396588.Tgr7_0763 4.82e-56 192.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_7158_1 1523503.JPMY01000031_gene3597 2.75e-90 277.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - Urate_ox_N k141_7158_2 1232683.ADIMK_3869 4.13e-92 272.0 COG3194@1|root,COG3194@2|Bacteria,1RE91@1224|Proteobacteria,1S4PA@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source allA - 4.3.2.3 ko:K01483 ko00230,ko01100,map00230,map01100 - R00776 RC00153,RC00379 ko00000,ko00001,ko01000 - - - Ureidogly_lyase k141_7158_3 1232683.ADIMK_3868 5.78e-162 458.0 COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,1RR90@1236|Gammaproteobacteria,469CD@72275|Alteromonadaceae 1236|Gammaproteobacteria F Allantoicase repeat alc GO:0003674,GO:0003824,GO:0004037,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.4 ko:K01477 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02422 RC00379,RC00712 ko00000,ko00001,ko00002,ko01000 - - - Allantoicase k141_20429_1 697282.Mettu_0563 3.01e-12 66.6 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX1M@1236|Gammaproteobacteria,1XG7H@135618|Methylococcales 135618|Methylococcales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_20429_2 1504672.669786061 3.86e-43 144.0 COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,2VTP9@28216|Betaproteobacteria 28216|Betaproteobacteria KT Response regulator receiver domain - - - - - - - - - - - - Response_reg k141_18310_1 580332.Slit_1177 4.86e-128 392.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria 28216|Betaproteobacteria M Penicillin-binding protein 1c pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase k141_20519_1 1177179.A11A3_00710 1.26e-91 278.0 COG2357@1|root,COG2357@2|Bacteria,1RBSQ@1224|Proteobacteria,1RR52@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Region found in RelA / SpoT proteins - - - - - - - - - - - - RelA_SpoT k141_9279_1 1278309.KB907100_gene1841 3.87e-38 137.0 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XIU6@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_9279_2 1278309.KB907100_gene1840 0.0 934.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XIDM@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_9279_3 1278309.KB907100_gene1839 2.2e-36 134.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1S6T6@1236|Gammaproteobacteria,1XKCA@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8620_1 1278309.KB907103_gene1108 2.74e-87 258.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XIJW@135619|Oceanospirillales 135619|Oceanospirillales H catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_8620_2 1278309.KB907103_gene1109 6.83e-106 308.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1XRDI@135619|Oceanospirillales 135619|Oceanospirillales S Smr domain - - - - - - - - - - - - Smr k141_8620_3 1278309.KB907103_gene1110 1.15e-204 568.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1XHF7@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_21879_1 1278309.KB907099_gene2459 2.96e-138 405.0 COG2204@1|root,COG2204@2|Bacteria,1QVPI@1224|Proteobacteria,1T2FZ@1236|Gammaproteobacteria,1XRSN@135619|Oceanospirillales 135619|Oceanospirillales T Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_21879_2 1278309.KB907099_gene2460 6.69e-49 159.0 2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,1SCEN@1236|Gammaproteobacteria,1XMDP@135619|Oceanospirillales 135619|Oceanospirillales S tryptophan synthase subunit beta - - - - - - - - - - - - - k141_4470_1 1121935.AQXX01000065_gene1676 1.38e-101 302.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1XHC3@135619|Oceanospirillales 135619|Oceanospirillales D Chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_3059_1 631362.Thi970DRAFT_00990 2.75e-104 313.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1WWQU@135613|Chromatiales 135613|Chromatiales E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_19109_1 472759.Nhal_1230 2.56e-63 206.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales 135613|Chromatiales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_19109_2 338963.Pcar_1257 2.42e-07 52.4 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family gnnB - - - - - - - - - - iAF987.Gmet_2351 DegT_DnrJ_EryC1 k141_7220_1 1123322.KB904680_gene3248 2.47e-10 62.8 COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria 201174|Actinobacteria H squalene-associated FAD-dependent desaturase hopC - - - - - - - - - - - Amino_oxidase k141_7220_2 1121921.KB898708_gene1430 3.83e-84 258.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,2PMT2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase yciK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short k141_12123_1 1236542.BALM01000031_gene1901 4.2e-59 190.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,2Q8MQ@267890|Shewanellaceae 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801 NTP_transf_3 k141_17696_1 96561.Dole_0171 7.87e-114 351.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MIZF@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM ABC transporter uup - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_17696_2 713587.THITH_06490 3.73e-25 97.4 2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,1S9XM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_246_1 1168067.JAGP01000001_gene1111 7e-63 202.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,45ZY5@72273|Thiotrichales 72273|Thiotrichales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_8621_1 529818.AMSG_08792T0 4.01e-06 54.3 KOG0498@1|root,KOG0498@2759|Eukaryota 2759|Eukaryota U voltage-gated potassium channel activity - - - - - - - - - - - - Ion_trans,Ion_trans_N,KHA,cNMP_binding k141_20520_1 999541.bgla_1g29270 2.26e-52 172.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_7221_1 1469613.JT55_12120 1.25e-08 56.2 296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2U6CK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_19110_1 1279017.AQYJ01000028_gene2145 1.71e-37 134.0 COG4122@1|root,COG4122@2|Bacteria,1RKKT@1224|Proteobacteria,1SP4T@1236|Gammaproteobacteria,46BV8@72275|Alteromonadaceae 1236|Gammaproteobacteria S O-methyltransferase activity - - - - - - - - - - - - - k141_1667_1 1517416.IDAT_01230 7.18e-12 68.6 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2QFJ5@267893|Idiomarinaceae 1236|Gammaproteobacteria S aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_1667_2 1166948.JPZL01000004_gene321 5.28e-17 81.6 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,HAMP,PAS_4,PAS_8 k141_21880_2 1123371.ATXH01000001_gene1269 5.27e-21 92.0 COG4623@1|root,COG4623@2|Bacteria 2|Bacteria M carbon-oxygen lyase activity, acting on polysaccharides mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_16248_1 398580.Dshi_0388 3.9e-154 436.0 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2TTN8@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC-type sugar transport system, ATPase component frcA - - ko:K10554 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - ABC_tran k141_16248_2 935557.ATYB01000014_gene1462 8.97e-45 154.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TRJJ@28211|Alphaproteobacteria,4B7A2@82115|Rhizobiaceae 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family frcC - - ko:K10553 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - BPD_transp_2 k141_4472_1 1237149.C900_05297 1.63e-80 266.0 COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2 k141_8622_1 1033743.CAES01000129_gene2591 1.7e-49 157.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,26ZFG@186822|Paenibacillaceae 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - k141_247_1 1288826.MSNKSG1_02013 5.22e-149 422.0 COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria 1236|Gammaproteobacteria T membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF347 k141_1668_1 314265.R2601_20336 7.92e-22 93.2 COG1737@1|root,COG1737@2|Bacteria,1R6J5@1224|Proteobacteria,2U06P@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS k141_5120_1 314231.FP2506_10516 2.66e-20 92.8 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,2PJZ8@255475|Aurantimonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1223) MA20_43790 - - - - - - - - - - - DUF1223 k141_5120_2 526222.Desal_2813 4.69e-17 80.1 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,42MVH@68525|delta/epsilon subdivisions,2WMHB@28221|Deltaproteobacteria,2M9JX@213115|Desulfovibrionales 28221|Deltaproteobacteria HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST k141_15598_1 1396858.Q666_12820 1.99e-156 456.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,46A2Y@72275|Alteromonadaceae 1236|Gammaproteobacteria CI Conserved carboxylase domain oadA - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5346 Biotin_lipoyl,HMGL-like,PYC_OADA k141_12124_1 323097.Nham_1013 1.18e-36 128.0 COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,3JYHF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k141_12124_2 399739.Pmen_1200 6.73e-14 70.5 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1YF2V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O AAA domain IV02_30220 - - ko:K04770 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k141_12802_2 1288826.MSNKSG1_12832 2.09e-265 728.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,46561@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD(FAD)-dependent dehydrogenases rubB - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_12802_3 1288826.MSNKSG1_12827 1.51e-199 553.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,464I0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyl-CoA thioesterase tesB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iAF1260.b0452,iB21_1397.B21_00408,iBWG_1329.BWG_0334,iEC55989_1330.EC55989_0466,iECBD_1354.ECBD_3203,iECB_1328.ECB_00404,iECDH10B_1368.ECDH10B_0408,iECDH1ME8569_1439.ECDH1ME8569_0437,iECD_1391.ECD_00404,iECH74115_1262.ECH74115_0541,iECIAI1_1343.ECIAI1_0456,iECIAI39_1322.ECIAI39_0221,iECO103_1326.ECO103_0429,iECO111_1330.ECO111_0485,iECO26_1355.ECO26_0487,iECSE_1348.ECSE_0478,iECSP_1301.ECSP_0520,iECUMN_1333.ECUMN_0492,iECW_1372.ECW_m0524,iECs_1301.ECs0506,iEKO11_1354.EKO11_3394,iETEC_1333.ETEC_0505,iEcDH1_1363.EcDH1_3157,iEcE24377_1341.EcE24377A_0488,iEcHS_1320.EcHS_A0529,iEcSMS35_1347.EcSMS35_0496,iEcolC_1368.EcolC_3163,iG2583_1286.G2583_0564,iJO1366.b0452,iSSON_1240.SSON_0440,iUMNK88_1353.UMNK88_505,iWFL_1372.ECW_m0524,iY75_1357.Y75_RS02335,iZ_1308.Z0564,ic_1306.c0571 4HBT_3,Acyl_CoA_thio k141_12802_4 1288826.MSNKSG1_12822 0.0 1579.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1QXG3@1224|Proteobacteria,1T3B7@1236|Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF k141_12802_5 1288826.MSNKSG1_12817 4.76e-99 288.0 COG0716@1|root,COG0716@2|Bacteria,1N27T@1224|Proteobacteria,1S906@1236|Gammaproteobacteria,467F1@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0716 Flavodoxins yqcA GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06205 - - - - ko00000 - - - Flavodoxin_1 k141_263_1 985054.JQEZ01000003_gene1374 1.16e-15 75.5 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,4NBIH@97050|Ruegeria 28211|Alphaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_21,AAA_23,SMC_N k141_263_2 439497.RR11_376 1.79e-50 169.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,4NBKF@97050|Ruegeria 28211|Alphaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_21889_1 1278309.KB907101_gene632 4.11e-174 497.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XI7E@135619|Oceanospirillales 135619|Oceanospirillales P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB - - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - - NhaB k141_21889_2 1278309.KB907101_gene633 9.91e-141 402.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1XJUP@135619|Oceanospirillales 135619|Oceanospirillales L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase k141_21889_3 207954.MED92_09256 3.44e-38 131.0 COG3255@1|root,COG3255@2|Bacteria,1N206@1224|Proteobacteria,1S8RI@1236|Gammaproteobacteria,1XKN0@135619|Oceanospirillales 135619|Oceanospirillales I SCP-2 sterol transfer family - - - - - - - - - - - - SCP2 k141_21889_4 1278309.KB907101_gene635 0.000338 42.4 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1XIW9@135619|Oceanospirillales 135619|Oceanospirillales OU peptidase sohB - - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_7978_2 314345.SPV1_13387 1.31e-23 97.8 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria 1224|Proteobacteria S Bile acid sodium symporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_9984_1 1444770.AF72_05240 7.92e-13 65.1 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1X871@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_9984_2 748247.AZKH_0589 1.18e-50 167.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales 206389|Rhodocyclales S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_20537_2 717231.Flexsi_1371 4.3e-23 99.4 COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres 200930|Deferribacteres NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_1693_1 795666.MW7_2649 3.27e-141 408.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,1K0EF@119060|Burkholderiaceae 28216|Betaproteobacteria C Isocitrate dehydrogenase icd GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_6498_1 553178.CAPGI0001_0211 2.64e-26 116.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,1EQGJ@1016|Capnocytophaga 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_5854_1 629265.PMA4326_19595 1.2e-11 64.7 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1Z938@136849|Pseudomonas syringae group 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB1 - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_5854_2 1198452.Jab_2c01080 2.86e-31 123.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GGDEF,PAS_4,PAS_9,Response_reg k141_15610_1 297246.lpp1249 1.25e-55 179.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1JD20@118969|Legionellales 118969|Legionellales K regulation of transcription, DNA-templated yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg k141_15610_2 1123255.JHYS01000014_gene552 3.96e-09 61.6 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,4ADC0@80864|Comamonadaceae 28216|Betaproteobacteria T PFAM Forkhead-associated protein - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_9297_1 690585.JNNU01000016_gene2697 8.21e-90 271.0 COG4177@1|root,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,4B7B0@82115|Rhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_12825_1 519989.ECTPHS_09033 1.87e-78 240.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1WWBK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_19124_2 1278309.KB907106_gene1311 4.58e-288 787.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XH22@135619|Oceanospirillales 135619|Oceanospirillales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_19124_4 1278309.KB907106_gene1313 1.34e-143 405.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1XI8V@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_19124_5 1278309.KB907106_gene1314 5.26e-131 373.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_19124_6 1278309.KB907106_gene1315 8.51e-27 99.4 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1XKG5@135619|Oceanospirillales 135619|Oceanospirillales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_13507_1 384765.SIAM614_17154 1.33e-186 523.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_3081_1 626887.J057_11971 6.01e-161 477.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,1QTVB@1224|Proteobacteria,1T35F@1236|Gammaproteobacteria,469B9@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_8,PAS_9,Response_reg k141_9985_1 1045856.EcWSU1_04527 1.86e-70 221.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,3WZUY@547|Enterobacter 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSSON_1240.SSON_3886,iYL1228.KPN_04138 ATP-synt k141_9985_2 870187.Thini_3031 2.08e-57 192.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales 72273|Thiotrichales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_21233_1 1123020.AUIE01000025_gene4782 2.41e-15 75.1 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RQ5E@1236|Gammaproteobacteria,1YF8Q@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Methyltransferase, chemotaxis proteins pilK - 2.1.1.80 ko:K00575,ko:K02661 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035,ko02044 - - - CheR,CheR_N k141_20538_1 1123518.ARWI01000001_gene539 6.87e-76 238.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria,4624H@72273|Thiotrichales 72273|Thiotrichales I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_14206_1 1122921.KB898185_gene3746 9.23e-13 74.7 COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,26SCI@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_5855_1 929562.Emtol_2551 5.02e-39 137.0 COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47XX0@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_15611_1 319236.JCM19294_1627 1.5e-65 205.0 COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1HZEU@117743|Flavobacteriia,3HKEP@363408|Nonlabens 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_5132_1 472759.Nhal_1179 4.76e-46 155.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1WXT6@135613|Chromatiales 135613|Chromatiales I PFAM phosphoesterase PA-phosphatase related - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_2334_1 573065.Astex_0832 2.39e-24 98.2 COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,2U7D2@28211|Alphaproteobacteria,2KK6T@204458|Caulobacterales 204458|Caulobacterales S MAPEG family - - - - - - - - - - - - MAPEG k141_2334_2 1120965.AUBV01000017_gene132 5.99e-10 65.1 COG0642@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47M3T@768503|Cytophagia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_971_1 571166.KI421509_gene1730 3.79e-66 210.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TT5Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor MA20_43200 - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_12826_1 1168067.JAGP01000001_gene986 9.64e-101 319.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,45ZS8@72273|Thiotrichales 72273|Thiotrichales C Belongs to the aconitase IPM isomerase family - - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_16268_1 1122201.AUAZ01000023_gene2999 3.25e-52 171.0 COG4107@1|root,COG4107@2|Bacteria,1MVRN@1224|Proteobacteria,1RR70@1236|Gammaproteobacteria,46AQN@72275|Alteromonadaceae 1236|Gammaproteobacteria P PFAM ABC transporter related phnK GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0071704,GO:1901575,GO:1902494,GO:1904176 - ko:K05781 - - - - ko00000 - - - ABC_tran k141_16268_2 1122201.AUAZ01000023_gene2998 4.61e-190 529.0 COG3627@1|root,COG3627@2|Bacteria,1MV7T@1224|Proteobacteria,1RNI7@1236|Gammaproteobacteria,469D1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose phnJ GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016829,GO:0018835,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0098848,GO:1901575,GO:1902494,GO:1904176 4.7.1.1 ko:K06163 ko00440,map00440 - R10204 RC03078,RC03079 ko00000,ko00001,ko01000 - - - PhnJ k141_16268_3 1122201.AUAZ01000023_gene2997 1.65e-108 322.0 COG3626@1|root,COG3626@2|Bacteria,1MUBA@1224|Proteobacteria,1RRT5@1236|Gammaproteobacteria,469G0@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bacterial phosphonate metabolism protein (PhnI) phnI GO:0003674,GO:0003824,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061693,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1904176,GO:1990234 2.7.8.37 ko:K06164 ko00440,map00440 - R10185 RC00005,RC00063 ko00000,ko00001,ko01000 - - - PhnI k141_21890_1 1198232.CYCME_1178 9.39e-170 511.0 COG0004@1|root,COG3852@1|root,COG5001@1|root,COG0004@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZWR@72273|Thiotrichales 72273|Thiotrichales PT Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS_9 k141_1695_1 1283284.AZUK01000001_gene1040 2.6e-22 100.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y3EI@135624|Aeromonadales 135624|Aeromonadales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_7251_1 1278309.KB907105_gene1469 5.9e-89 266.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1XJAQ@135619|Oceanospirillales 135619|Oceanospirillales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_7251_2 1122599.AUGR01000017_gene2928 9.41e-45 151.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1SB1T@1236|Gammaproteobacteria,1XKJU@135619|Oceanospirillales 135619|Oceanospirillales O FKBP-type peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - FKBP_C k141_7251_3 521000.PROVRETT_05615 1.39e-26 97.8 COG0401@1|root,COG0401@2|Bacteria,1N9JZ@1224|Proteobacteria,1SCHH@1236|Gammaproteobacteria,3Z9GV@586|Providencia 1236|Gammaproteobacteria S Proteolipid membrane potential modulator - - - - - - - - - - - - Pmp3 k141_11441_1 1288826.MSNKSG1_13507 3.39e-90 272.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,465UN@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_15750_3 243277.VC_2722 2.08e-25 104.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XUIT@135623|Vibrionales 135623|Vibrionales P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_21330_1 1278309.KB907102_gene23 3.49e-135 394.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XIF7@135619|Oceanospirillales 135619|Oceanospirillales G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_3210_1 1137799.GZ78_17595 1.05e-92 278.0 2AIRP@1|root,34860@2|Bacteria,1P3DA@1224|Proteobacteria 1137799.GZ78_17595|- S tRNAHis guanylyltransferase - - - - - - - - - - - - - k141_13636_2 365046.Rta_03320 1.39e-27 107.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,4A9J7@80864|Comamonadaceae 28216|Betaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_4594_1 1192868.CAIU01000013_gene1752 3.32e-06 52.4 COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,2TU5T@28211|Alphaproteobacteria,43IK0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate tam - 2.1.1.144 ko:K00598 - - - - ko00000,ko01000 - - - Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_17829_1 1278309.KB907100_gene2017 0.0 1249.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XHS8@135619|Oceanospirillales 135619|Oceanospirillales DM COG3264 Small-conductance mechanosensitive channel - - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - MS_channel,MscS_TM,MscS_porin k141_10871_1 1123518.ARWI01000001_gene1641 1.4e-79 249.0 COG2132@1|root,COG2132@2|Bacteria,1R89G@1224|Proteobacteria,1S5X0@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_3 k141_10871_2 1535422.ND16A_1815 1.46e-72 233.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 k141_17095_1 1291050.JAGE01000001_gene3068 3.77e-38 146.0 COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,24YJI@186801|Clostridia 186801|Clostridia Q Beta-ketoacyl synthase - - - - - - - - - - - - Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt k141_17095_2 232721.Ajs_3072 1.37e-143 424.0 COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2WGHK@28216|Betaproteobacteria,4AF4Y@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Cytochrome P450 - - 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_12970_1 1288826.MSNKSG1_05381 3.74e-115 336.0 COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,1RMQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria P thiamine ABC transporter tbpA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015888,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0030975,GO:0030976,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0045117,GO:0048037,GO:0050662,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0071702,GO:0071705,GO:0072348,GO:0097159,GO:1901363,GO:1901681 - ko:K02064 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - iAPECO1_1312.APECO1_1914,iSFxv_1172.SFxv_0065,iUTI89_1310.UTI89_C0076 SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8 k141_12970_2 1288826.MSNKSG1_05376 0.0 1031.0 COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria 1236|Gammaproteobacteria P with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell thiP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - ko:K02063 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - iAPECO1_1312.APECO1_1915,iECIAI1_1343.ECIAI1_0067,iECO103_1326.ECO103_0068,iECO111_1330.ECO111_0069,iECO26_1355.ECO26_0069,iECOK1_1307.ECOK1_0068,iECS88_1305.ECS88_0072,iECSE_1348.ECSE_0067,iECUMN_1333.ECUMN_0068,iPC815.YPO0521,iSF_1195.SF0062,iSFxv_1172.SFxv_0064,iS_1188.S0064,iUMN146_1321.UM146_23130,iUTI89_1310.UTI89_C0075 BPD_transp_1 k141_12970_3 1288826.MSNKSG1_05371 3.87e-139 394.0 COG3840@1|root,COG3840@2|Bacteria,1MV78@1224|Proteobacteria,1RQH3@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system thiQ GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0006855,GO:0008144,GO:0008150,GO:0015234,GO:0015238,GO:0015399,GO:0015405,GO:0015888,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0072348,GO:0072531,GO:0090482,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901474,GO:1901682 - ko:K02062 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - iAF1260.b0066,iEC55989_1330.EC55989_0064,iECABU_c1320.ECABU_c00740,iECDH1ME8569_1439.ECDH1ME8569_0065,iECO103_1326.ECO103_0067,iECO111_1330.ECO111_0068,iECO26_1355.ECO26_0068,iECSE_1348.ECSE_0066,iETEC_1333.ETEC_0065,iEcDH1_1363.EcDH1_3533,iJO1366.b0066,iJR904.b0066,iUMNK88_1353.UMNK88_64,iY75_1357.Y75_RS00335,ic_1306.c0082 ABC_tran k141_12970_4 1288826.MSNKSG1_05366 2.11e-17 80.5 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents permease component mlaE_1 - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS_2 k141_1110_1 312309.VF_2324 1.92e-62 200.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XSXN@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_22008_1 1288826.MSNKSG1_10813 1.63e-136 395.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,469RP@72275|Alteromonadaceae 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_22008_2 1288826.MSNKSG1_10808 1.81e-291 798.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,4669T@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_22008_3 1288826.MSNKSG1_10803 1.3e-93 281.0 COG1639@1|root,COG1639@2|Bacteria,1RJ09@1224|Proteobacteria,1SZ60@1236|Gammaproteobacteria,46CXA@72275|Alteromonadaceae 1236|Gammaproteobacteria T HDOD domain - - - - - - - - - - - - HDOD k141_8131_1 1288826.MSNKSG1_13742 9.69e-248 683.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,467IV@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_15012_1 2340.JV46_15540 2.73e-10 61.6 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 k141_15012_3 395493.BegalDRAFT_3111 3.62e-37 129.0 COG3829@1|root,COG3829@2|Bacteria,1QZHD@1224|Proteobacteria,1S631@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT transcription factor binding - - - - - - - - - - - - - k141_10136_1 1260251.SPISAL_00300 3.91e-43 159.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_12270_2 765912.Thimo_2956 5.03e-31 111.0 COG2154@1|root,COG2154@2|Bacteria,1N7XJ@1224|Proteobacteria,1T12K@1236|Gammaproteobacteria,1X2MX@135613|Chromatiales 135613|Chromatiales H Pterin 4 alpha carbinolamine dehydratase - - - - - - - - - - - - Pterin_4a k141_12270_3 426114.THI_0147 2.55e-09 58.5 COG1192@1|root,COG1192@2|Bacteria,1RACE@1224|Proteobacteria,2VSW2@28216|Betaproteobacteria,1KPIS@119065|unclassified Burkholderiales 28216|Betaproteobacteria D Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_6623_1 270374.MELB17_23350 2.78e-107 325.0 COG0477@1|root,COG2814@2|Bacteria,1QV32@1224|Proteobacteria,1T3MY@1236|Gammaproteobacteria,46D5H@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 k141_21331_2 1177154.Y5S_01465 1.54e-14 70.9 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1XM6I@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III chi subunit holC - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_15752_2 351016.RAZWK3B_18098 8.36e-28 107.0 28J78@1|root,2Z92P@2|Bacteria,1PEDU@1224|Proteobacteria,2TT0K@28211|Alphaproteobacteria,2P2YP@2433|Roseobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_407_1 796620.VIBC2010_07689 5.61e-42 144.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1XUUK@135623|Vibrionales 135623|Vibrionales O Protein-disulfide isomerase VP2116 - - ko:K07396 - - - - ko00000 - - - Thioredoxin_5 k141_1111_1 686340.Metal_2497 8.74e-90 272.0 COG0482@1|root,COG0482@2|Bacteria,1QV6H@1224|Proteobacteria,1RQSV@1236|Gammaproteobacteria,1XH1D@135618|Methylococcales 135618|Methylococcales J Thiamine biosynthesis protein (ThiI) - - - - - - - - - - - - - k141_12971_1 1288826.MSNKSG1_17271 2.53e-112 331.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_1807_1 1434325.AZQN01000003_gene2767 7.37e-22 93.6 COG2091@1|root,COG2091@2|Bacteria,4NSR9@976|Bacteroidetes,47S70@768503|Cytophagia 976|Bacteroidetes H 4'-phosphopantetheinyl transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_1807_2 391615.ABSJ01000004_gene643 4.04e-69 218.0 COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1T7TI@1236|Gammaproteobacteria,1JB79@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF374) - - - - - - - - - - - - DUF374 k141_18499_1 1123368.AUIS01000001_gene1968 1.6e-104 322.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,2NCDA@225057|Acidithiobacillales 225057|Acidithiobacillales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_22009_1 391615.ABSJ01000039_gene1877 5.96e-29 117.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1J4S5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG4942 Membrane-bound metallopeptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 k141_8132_1 1442599.JAAN01000005_gene946 1e-106 323.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1X4FV@135614|Xanthomonadales 135614|Xanthomonadales C IG-like fold at C-terminal of FixG, putative oxidoreductase - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_20632_1 1163408.UU9_11838 0.000457 44.7 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1X40P@135614|Xanthomonadales 135614|Xanthomonadales M murein transglycosylase mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_20632_2 380703.AHA_3255 6.79e-103 310.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1Y427@135624|Aeromonadales 135624|Aeromonadales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_4595_1 89187.ISM_15900 1.55e-22 91.7 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,46QX7@74030|Roseovarius 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB GO:0003674,GO:0005215 - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_4595_2 999611.KI421504_gene2290 1.61e-25 96.7 COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2V23Y@28211|Alphaproteobacteria,281WX@191028|Leisingera 28211|Alphaproteobacteria U mttA/Hcf106 family - - - - - - - - - - - - MttA_Hcf106 k141_7358_1 1283300.ATXB01000001_gene1972 7.33e-43 170.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GGDEF,PAS_4 k141_17830_1 1278309.KB907103_gene1128 1.46e-62 202.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XHYW@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_1112_1 1123518.ARWI01000001_gene671 7.02e-60 187.0 COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,460PH@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox k141_9398_1 1288826.MSNKSG1_02133 1.54e-316 866.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8 k141_9398_2 1288826.MSNKSG1_02128 1.95e-174 495.0 2C2XP@1|root,32WP3@2|Bacteria,1N3V4@1224|Proteobacteria,1SBUM@1236|Gammaproteobacteria,46DH5@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5942_1 1278309.KB907111_gene3377 0.0 2228.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XHB4@135619|Oceanospirillales 135619|Oceanospirillales E Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_5942_2 1232683.ADIMK_4084 3.57e-149 425.0 COG0672@1|root,COG0672@2|Bacteria 2|Bacteria P high-affinity ferrous iron transmembrane transporter activity - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_5942_3 1232683.ADIMK_4083 8.05e-51 162.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,1SDG5@1236|Gammaproteobacteria,468VC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_5942_4 1278309.KB907111_gene3378 8.96e-93 271.0 COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,1XJX4@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox k141_5942_5 1278309.KB907111_gene3379 2.06e-215 608.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,1XIX7@135619|Oceanospirillales 135619|Oceanospirillales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases prpE - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_6624_1 1198232.CYCME_1738 1.99e-38 147.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,45ZUT@72273|Thiotrichales 72273|Thiotrichales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_16388_1 1177154.Y5S_01375 3.61e-22 106.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XI39@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein - - - ko:K07121 - - - - ko00000 - - - LppC k141_16388_2 93059.P9211_12801 2.2e-10 60.8 COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1MKZA@1212|Prochloraceae 1117|Cyanobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_1808_1 1122599.AUGR01000002_gene3477 2.3e-87 271.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1XHBB@135619|Oceanospirillales 135619|Oceanospirillales C oxidase, subunit - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_14289_1 1288826.MSNKSG1_04011 2.29e-152 432.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_14289_2 351348.Maqu_0926 9.57e-168 470.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,465IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - iSFxv_1172.SFxv_3035 SurE k141_14289_3 1288826.MSNKSG1_04026 3.55e-151 425.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,465SD@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_14289_4 1288826.MSNKSG1_04031 3.72e-206 572.0 COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,466EX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 k141_14289_5 1288826.MSNKSG1_04036 1.8e-189 527.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,466TP@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0739 Membrane proteins related to metalloendopeptidases nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - ko:K06194,ko:K12943 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_14289_6 1288826.MSNKSG1_04041 4.56e-135 388.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,4641K@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70 sigma32) rpoS GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_22010_1 857087.Metme_0152 5.12e-37 131.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XE8S@135618|Methylococcales 135618|Methylococcales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_21332_1 1123399.AQVE01000035_gene3168 5.93e-73 238.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3 k141_13639_1 84531.JMTZ01000067_gene1718 7.39e-43 145.0 COG0454@1|root,COG0454@2|Bacteria,1RDBA@1224|Proteobacteria,1S225@1236|Gammaproteobacteria,1X626@135614|Xanthomonadales 135614|Xanthomonadales K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_13639_2 471874.PROSTU_03148 2.81e-05 46.6 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,3Z7A9@586|Providencia 1236|Gammaproteobacteria H Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_12271_1 396588.Tgr7_0127 7.59e-91 280.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_10138_1 1304885.AUEY01000053_gene140 2.19e-30 124.0 COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2WKH4@28221|Deltaproteobacteria,2MIRQ@213118|Desulfobacterales 28221|Deltaproteobacteria H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group cobD - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib k141_3214_1 313606.M23134_04741 2.87e-37 133.0 28PD0@1|root,2ZC53@2|Bacteria,4NM6X@976|Bacteroidetes,47PYX@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_4596_1 1049564.TevJSym_ac01200 1.16e-132 394.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_8747_2 452637.Oter_3727 5.55e-10 62.4 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_1127_1 1449351.RISW2_01960 9.55e-22 91.7 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1127_2 1449351.RISW2_01965 2.51e-33 126.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,4KN96@93682|Roseivivax 28211|Alphaproteobacteria C Aldehyde dehydrogenase - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_5957_1 1123368.AUIS01000005_gene313 1.04e-21 98.6 COG2223@1|root,COG2223@2|Bacteria,1QVWW@1224|Proteobacteria,1T2M5@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_21343_1 266265.Bxe_A3034 6.43e-40 152.0 COG2202@1|root,COG3614@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - CHASE,EAL,GGDEF,PAS_3,PAS_4,PAS_9 k141_13659_2 1026882.MAMP_00291 1.22e-57 182.0 2E1WQ@1|root,32X5W@2|Bacteria,1N2F8@1224|Proteobacteria,1SA2N@1236|Gammaproteobacteria,462KZ@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_12283_1 1278309.KB907100_gene1851 9.62e-206 577.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XHQS@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_12283_2 1278309.KB907100_gene1852 2.92e-213 592.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XID6@135619|Oceanospirillales 135619|Oceanospirillales T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_12283_3 999141.GME_06874 4.91e-55 177.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XJZW@135619|Oceanospirillales 135619|Oceanospirillales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_12283_4 1278309.KB907100_gene1854 2.56e-135 387.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1XHEY@135619|Oceanospirillales 135619|Oceanospirillales P transporter corC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_17851_1 1114964.L485_15015 1.25e-36 138.0 COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,2K0BT@204457|Sphingomonadales 204457|Sphingomonadales TU Flp pilus assembly protein, ATPase CpaE cpaE - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - CbiA,ParA k141_14303_1 1122164.JHWF01000010_gene2443 6.44e-91 293.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1JDMR@118969|Legionellales 118969|Legionellales M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase k141_6093_6 1288826.MSNKSG1_17201 9.2e-172 482.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,464BI@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_6093_7 1288826.MSNKSG1_17206 0.0 1169.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,463Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N,AcylCoA_dehyd_C k141_6093_8 1288826.MSNKSG1_17211 1.02e-150 426.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,467FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) csgA - - - - - - - - - - - adh_short k141_6093_9 1288826.MSNKSG1_17216 1.77e-148 418.0 COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,1S2IS@1236|Gammaproteobacteria,46DNT@72275|Alteromonadaceae 1236|Gammaproteobacteria T AntiSigma factor chrR - - ko:K07167 - - - - ko00000 - - - Cupin_7 k141_6093_10 1288826.MSNKSG1_17221 2.64e-139 394.0 COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,46820@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_12452_1 1234364.AMSF01000025_gene3652 3.21e-94 293.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1X497@135614|Xanthomonadales 135614|Xanthomonadales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_11684_1 1288826.MSNKSG1_12692 5.4e-43 150.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein k141_11684_2 1288826.MSNKSG1_12697 1.18e-152 429.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,466E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_11684_5 1288826.MSNKSG1_12712 1.16e-208 576.0 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RYBE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Exo_endo_phos k141_11684_6 1288826.MSNKSG1_12717 8.97e-136 385.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,466ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins dsbA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k141_8265_1 1123401.JHYQ01000001_gene1884 3.08e-36 133.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_5456_2 292415.Tbd_0601 8.69e-127 370.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,2VN1T@28216|Betaproteobacteria,1KSVG@119069|Hydrogenophilales 119069|Hydrogenophilales C Domain of unknown function (DUF4931) - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - - k141_13134_1 269799.Gmet_1142 5.74e-138 412.0 COG3292@1|root,COG3292@2|Bacteria,1QMJ4@1224|Proteobacteria,42RQF@68525|delta/epsilon subdivisions,2WNII@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Two component regulator propeller - - - - - - - - - - - - Tail_P2_I k141_13134_2 1144275.COCOR_01891 1.73e-65 225.0 COG3391@1|root,COG3391@2|Bacteria,1QWR8@1224|Proteobacteria,43CAC@68525|delta/epsilon subdivisions,2X7KW@28221|Deltaproteobacteria 28221|Deltaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - k141_19387_1 1123237.Salmuc_01623 5.05e-91 276.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1280_1 439235.Dalk_5003 9.13e-63 202.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_13839_6 1288826.MSNKSG1_18285 5.09e-139 393.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,466YT@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3167 Tfp pilus assembly protein PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_13839_7 1288826.MSNKSG1_18280 2.18e-123 352.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,467DK@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3166 Tfp pilus assembly protein PilN pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_13839_8 1288826.MSNKSG1_18275 1.91e-239 660.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,465IC@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4972 Tfp pilus assembly protein, ATPase PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_13839_9 1288826.MSNKSG1_18270 0.0 1360.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,464YC@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG5009 Membrane carboxypeptidase penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_13839_10 1288826.MSNKSG1_18265 1.3e-204 572.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,465MY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0281 Malic enzyme maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_8863_2 207954.MED92_02279 2.03e-54 174.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XJZ5@135619|Oceanospirillales 135619|Oceanospirillales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_11054_1 643867.Ftrac_1316 1.19e-26 101.0 2E1V4@1|root,32X4G@2|Bacteria,4NTMM@976|Bacteroidetes,47RT0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_11054_2 1122176.KB903539_gene1320 1.06e-09 56.6 COG0454@1|root,COG0456@2|Bacteria,4NPGI@976|Bacteroidetes,1ITRY@117747|Sphingobacteriia 976|Bacteroidetes K Acetyltransferase (GNAT) domain yjaB - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_10 k141_2629_2 1209072.ALBT01000028_gene1213 0.000471 45.8 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1FGXU@10|Cellvibrio 1236|Gammaproteobacteria T Histidine Phosphotransfer domain - - - - - - - - - - - - GGDEF,HDOD,Hpt,Response_reg k141_2629_3 1117319.PSPO_04052 1.27e-26 108.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,2Q04A@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281 GATase_6,SIS k141_14433_2 1453505.JASY01000010_gene4008 3.18e-05 48.9 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia,2NS9E@237|Flavobacterium 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y k141_20740_1 1278309.KB907100_gene1899 4.99e-90 290.0 COG1502@1|root,COG1502@2|Bacteria,1R5BX@1224|Proteobacteria 1224|Proteobacteria I phospholipase d transphosphatidylase - - - - - - - - - - - - PLDc_2 k141_3373_1 472759.Nhal_3503 2.66e-162 462.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1X02A@135613|Chromatiales 135613|Chromatiales F Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase k141_12474_1 159087.Daro_1418 1.34e-102 305.0 28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2VM9W@28216|Betaproteobacteria,2KV5B@206389|Rhodocyclales 206389|Rhodocyclales S SIR2-like domain - - - - - - - - - - - - SIR2_2 k141_18042_1 1278309.KB907112_gene3343 0.0 1160.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_22180_1 1116472.MGMO_111c00230 4.2e-13 77.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XECU@135618|Methylococcales 135618|Methylococcales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_9550_1 83406.HDN1F_33620 8.94e-14 68.2 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S YcgL domain-containing protein ycgL - - ko:K09902 - - - - ko00000 - - - YcgL k141_9550_2 932213.SPM24T3_21519 1.13e-74 230.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,3ZZS5@613|Serratia 1236|Gammaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_8864_1 1535422.ND16A_0786 9.57e-99 296.0 COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,1RRJE@1236|Gammaproteobacteria,2Q5XW@267889|Colwelliaceae 1236|Gammaproteobacteria E Putative serine dehydratase domain - - 4.1.2.42,4.1.3.41 ko:K18425,ko:K19967 - - - - ko00000,ko01000 - - - Ala_racemase_N,D-ser_dehydrat k141_8864_2 1232683.ADIMK_3886 1.68e-40 141.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,46519@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine dehydratase tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_13155_1 1122212.AULO01000007_gene2600 4.8e-54 187.0 COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,1S4PZ@1236|Gammaproteobacteria,1XR61@135619|Oceanospirillales 135619|Oceanospirillales T HD domain - - - - - - - - - - - - HD_5 k141_16570_3 472759.Nhal_1451 3.41e-67 206.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales 135613|Chromatiales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_10323_1 1448139.AI20_14655 1.38e-25 105.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1Y3H8@135624|Aeromonadales 135624|Aeromonadales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_10323_2 574966.KB898646_gene3024 3.07e-49 163.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1XK71@135619|Oceanospirillales 135619|Oceanospirillales S ATPase or kinase - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_14434_1 1163409.UUA_15683 6.03e-56 182.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria,1X5QD@135614|Xanthomonadales 135614|Xanthomonadales I acetyltransferase plsC1 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_14434_2 1234364.AMSF01000025_gene3606 2.13e-07 50.4 COG1522@1|root,COG1522@2|Bacteria,1QSAH@1224|Proteobacteria,1T01I@1236|Gammaproteobacteria,1X6KV@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_11055_1 1232437.KL662020_gene828 8.63e-31 118.0 COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2MKPY@213118|Desulfobacterales 28221|Deltaproteobacteria S Carboxypeptidase controlling helical cell shape catalytic - - - - - - - - - - - - Peptidase_M99,Peptidase_M99_C k141_11055_2 1163617.SCD_n02060 1.38e-24 107.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria 1224|Proteobacteria C oxidoreductase FAD NAD(P)-binding domain protein - - - - - - - - - - - - FAD_binding_6,Fer2 k141_22181_1 351016.RAZWK3B_06967 9.04e-79 258.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria,2P24C@2433|Roseobacter 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhF - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_19401_1 75379.Tint_1660 3.3e-44 160.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,1KJCI@119065|unclassified Burkholderiales 28216|Betaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_19401_2 95619.PM1_0210095 6.12e-18 80.1 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_7533_1 1278309.KB907100_gene2047 1.23e-89 264.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1XK51@135619|Oceanospirillales 135619|Oceanospirillales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_7533_2 1278309.KB907100_gene2048 8.32e-102 296.0 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1XK1S@135619|Oceanospirillales 135619|Oceanospirillales F uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_7533_3 1278309.KB907100_gene2049 1.57e-216 600.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1XIZ1@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_7533_4 1278309.KB907100_gene2050 8.12e-87 267.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1XH2Y@135619|Oceanospirillales 135619|Oceanospirillales F Dihydroorotase multifunctional complex type pyrC-2 - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_16571_1 1215114.BBIU01000013_gene1854 4.07e-39 137.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Aldolase eda GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - iECOK1_1307.ECOK1_1968,iYL1228.KPN_02365 Aldolase k141_16571_2 1035839.AFNK01000006_gene1878 5.51e-17 76.6 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,1Y8HY@135625|Pasteurellales 135625|Pasteurellales G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS k141_12475_1 1484157.PSNIH2_11750 3.07e-08 56.2 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,3VXU4@53335|Pantoea 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_12475_2 1123368.AUIS01000003_gene1665 1.73e-36 127.0 COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,2NDA0@225057|Acidithiobacillales 225057|Acidithiobacillales K MarR family - - - - - - - - - - - - HTH_24 k141_8865_2 292415.Tbd_2327 4.24e-41 138.0 COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria,2W3KZ@28216|Betaproteobacteria 28216|Betaproteobacteria P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_10324_1 1198232.CYCME_0419 3.23e-06 50.4 COG3571@1|root,COG3571@2|Bacteria,1R28T@1224|Proteobacteria,1T5JE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3530) - - - - - - - - - - - - DUF3530 k141_10324_2 713586.KB900536_gene1671 6.79e-63 197.0 COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,1WZE3@135613|Chromatiales 135613|Chromatiales S Copper resistance protein D - - - - - - - - - - - - CopD k141_20017_1 984262.SGRA_0345 2.78e-54 173.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia 976|Bacteroidetes G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB k141_20017_2 926556.Echvi_0906 3.05e-47 168.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate k141_9551_1 1049564.TevJSym_ai00340 8.15e-143 429.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1J534@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_15930_1 1123393.KB891316_gene1510 1.17e-127 379.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,1KSI6@119069|Hydrogenophilales 119069|Hydrogenophilales S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_13156_1 398767.Glov_1969 8.71e-51 184.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_18696_1 1122201.AUAZ01000009_gene2878 1.44e-212 622.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_3997_1 754477.Q7C_704 2.15e-40 149.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales 72273|Thiotrichales V ABC transporter transmembrane region - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_3997_2 568768.CM001975_gene2634 0.000406 43.9 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,2JCVX@204037|Dickeya 1236|Gammaproteobacteria M HlyD family secretion protein lssD - - ko:K02022,ko:K12542 - M00330 - - ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 - - Biotin_lipoyl_2,HlyD,HlyD_3 k141_6766_1 768671.ThimaDRAFT_4368 5.34e-303 839.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1WW8W@135613|Chromatiales 135613|Chromatiales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_4779_2 1288826.MSNKSG1_17930 6.2e-62 191.0 2DR7A@1|root,33AIK@2|Bacteria,1NGEC@1224|Proteobacteria,1SGK6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - mshK - - ko:K12281 - - - - ko00000,ko02044 - - - - k141_4779_3 1288826.MSNKSG1_17925 1.86e-133 381.0 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,1S8XS@1236|Gammaproteobacteria,46DFF@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretion system (T2SS), protein M mshJ - - ko:K12280 - - - - ko00000,ko02044 - - - PilO,T2SSM k141_18045_1 765910.MARPU_14340 7.43e-98 308.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales 135613|Chromatiales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_13841_1 1380394.JADL01000012_gene817 6.68e-83 256.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2U4DC@28211|Alphaproteobacteria,2JU62@204441|Rhodospirillales 204441|Rhodospirillales S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_13841_2 317025.Tcr_1803 1.4e-79 243.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1S357@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B k141_2630_2 1122963.AUHB01000016_gene4362 2.8e-11 65.5 COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,2U9KJ@28211|Alphaproteobacteria,36YM7@31993|Methylocystaceae 28211|Alphaproteobacteria K NikR C terminal nickel binding domain nikR GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 k141_2630_3 1026882.MAMP_01700 1.82e-150 429.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RRKD@1236|Gammaproteobacteria,463MW@72273|Thiotrichales 72273|Thiotrichales P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_9552_1 1205908.AKXW01000018_gene2688 1.82e-31 117.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1XTXV@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0307 family yjgA - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_3375_1 1278309.KB907101_gene351 3e-47 161.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RPA8@1236|Gammaproteobacteria,1XI8Q@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_3375_2 1415755.JQLV01000001_gene3541 5.19e-30 124.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJF8@135619|Oceanospirillales 135619|Oceanospirillales NT PFAM Chemotaxis methyl-accepting receptor, signalling - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_11058_1 525244.HMPREF0023_0052 1.36e-11 64.7 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,3NN6W@468|Moraxellaceae 1236|Gammaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_8866_1 926554.KI912633_gene4039 3.58e-59 207.0 COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg k141_13157_1 1123393.KB891328_gene642 3.58e-69 221.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,2VN1T@28216|Betaproteobacteria,1KSVG@119069|Hydrogenophilales 119069|Hydrogenophilales C Domain of unknown function (DUF4931) - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - - k141_7534_1 105559.Nwat_0472 7.23e-23 95.1 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WXUC@135613|Chromatiales 135613|Chromatiales S ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_7534_2 472759.Nhal_0556 4.85e-70 229.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1WX3X@135613|Chromatiales 135613|Chromatiales N PFAM ABC-type uncharacterised transport system - - - - - - - - - - - - ABC_transp_aux k141_17420_2 396588.Tgr7_1241 5.22e-179 505.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales 135613|Chromatiales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_9054_2 768671.ThimaDRAFT_1427 2.66e-67 207.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1WY24@135613|Chromatiales 135613|Chromatiales O redox protein, regulator of disulfide bond formation - - - ko:K07397 - - - - ko00000 - - - OsmC k141_9054_3 1121921.KB898707_gene1088 1.21e-66 208.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,2PN0Z@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T helix_turn_helix, cAMP Regulatory protein crp GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,cNMP_binding k141_15249_1 1424334.W822_12740 1.86e-25 98.2 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2VU19@28216|Betaproteobacteria,3T44U@506|Alcaligenaceae 28216|Betaproteobacteria J translation initiation inhibitor, yjgF family - - - - - - - - - - - - Ribonuc_L-PSP k141_16725_1 1249627.D779_3988 2.24e-05 47.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1WWJP@135613|Chromatiales 135613|Chromatiales S Sterol-binding domain protein - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_16725_3 1123393.KB891333_gene2507 8.28e-106 317.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales 119069|Hydrogenophilales G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_4064_1 744979.R2A130_3259 1.37e-54 190.0 COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2TRRK@28211|Alphaproteobacteria 28211|Alphaproteobacteria I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons pct - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_2069_1 1126627.BAWE01000002_gene462 1.93e-05 48.9 COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,3JTG9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_2069_2 298653.Franean1_5041 3.49e-15 76.3 COG0604@1|root,COG0604@2|Bacteria,2HHN3@201174|Actinobacteria,4EU5Q@85013|Frankiales 201174|Actinobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_16726_1 1123518.ARWI01000001_gene1495 3.32e-06 48.5 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,460R5@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_16726_2 225937.HP15_3609 3.39e-38 134.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Domain of unknown function DUF302 - - - - - - - - - - - - Beta-lactamase,DUF302 k141_14590_1 1353528.DT23_05090 6.87e-91 281.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2XMFE@285107|Thioclava 28211|Alphaproteobacteria G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_17422_1 987059.RBXJA2T_18041 1.11e-11 66.2 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,1KJ34@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_17422_2 1026882.MAMP_03014 6.13e-13 68.6 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,460W6@72273|Thiotrichales 72273|Thiotrichales M Belongs to the skp family - - - ko:K06142 - - - - ko00000 - - - OmpH k141_15250_1 1163617.SCD_n02361 4.77e-37 139.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3 k141_15250_2 314287.GB2207_10658 4.42e-25 102.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_16727_1 1134474.O59_000056 5.4e-66 215.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1FH21@10|Cellvibrio 1236|Gammaproteobacteria U Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_9693_1 1288826.MSNKSG1_02073 9.33e-62 208.0 COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,1RMJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - - - - - - - - - - Peptidase_M19,Ricin_B_lectin k141_9693_2 1163671.JAGI01000002_gene3130 6.71e-27 106.0 COG0454@1|root,COG0456@2|Bacteria,1V5VU@1239|Firmicutes,24JBE@186801|Clostridia,36K0C@31979|Clostridiaceae 186801|Clostridia K Acetyltransferase (GNAT) domain - - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_10 k141_9693_3 1288826.MSNKSG1_02078 7.57e-80 237.0 COG5395@1|root,COG5395@2|Bacteria,1N0CF@1224|Proteobacteria,1SBQ3@1236|Gammaproteobacteria,468HR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2306) - - - - - - - - - - - - DUF2306 k141_2070_1 1173263.Syn7502_01821 2.78e-17 86.7 COG0642@1|root,COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria 2|Bacteria T response regulator, receiver - - 1.8.1.9,2.7.13.3 ko:K00384,ko:K03407 ko00450,ko02020,ko02030,map00450,map02020,map02030 M00506 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CBS,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg k141_6843_1 1232410.KI421426_gene1483 1.49e-24 99.0 29WX2@1|root,30IJ3@2|Bacteria,1Q0W8@1224|Proteobacteria,433PA@68525|delta/epsilon subdivisions,2WXEY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Cysteine rich repeat - - - - - - - - - - - - Cys_rich_FGFR k141_14591_1 870187.Thini_1703 2.98e-88 275.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales 72273|Thiotrichales T PFAM response regulator receiver - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_9055_1 1288826.MSNKSG1_16856 1.04e-102 298.0 COG0784@1|root,COG0784@2|Bacteria 2|Bacteria T Response regulator, receiver - - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,Response_reg k141_9055_2 1288826.MSNKSG1_16851 0.0 1035.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_17423_1 1184607.AUCHE_04_00870 7.53e-14 73.6 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4F664@85018|Dermatophilaceae 201174|Actinobacteria K helix_turn_helix, cAMP Regulatory protein glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_17423_2 491952.Mar181_0836 5.57e-23 91.3 COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,1SCWV@1236|Gammaproteobacteria,1XM0Q@135619|Oceanospirillales 135619|Oceanospirillales S the cytoplasmic domain of flagellar protein - - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 k141_20865_3 1288826.MSNKSG1_17885 1.71e-143 405.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,464TW@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_20865_5 1288826.MSNKSG1_17875 1.1e-76 229.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,467N1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_20865_6 1288826.MSNKSG1_17865 2.02e-305 834.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,46418@72275|Alteromonadaceae 1236|Gammaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_20865_7 1288826.MSNKSG1_17860 3e-91 268.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,4670D@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_20865_8 1288826.MSNKSG1_17855 1.08e-37 126.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,468BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L30 rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_20865_9 1288826.MSNKSG1_17850 1.93e-109 315.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,464RY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_20865_10 1288826.MSNKSG1_17845 2.34e-72 218.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,4679B@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_20865_11 1288826.MSNKSG1_17840 6.63e-120 343.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,466EY@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_20865_12 1288826.MSNKSG1_17835 1.82e-83 247.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,46724@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_20865_13 1288826.MSNKSG1_17830 1.02e-64 197.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,467UW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_20865_14 1288826.MSNKSG1_17825 3.55e-125 356.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,464A7@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_20865_15 1288826.MSNKSG1_17820 1.93e-69 209.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,467RK@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_20865_17 1122197.ATWI01000013_gene2368 1.37e-53 168.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,467RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_20865_18 1288826.MSNKSG1_17805 2.19e-33 115.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,468D6@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_20865_19 1288826.MSNKSG1_17800 4.19e-90 264.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,466H8@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_20865_20 1288826.MSNKSG1_17795 6.88e-158 443.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,46670@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_20865_21 1288826.MSNKSG1_17790 1.75e-67 205.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,467D4@72275|Alteromonadaceae 1236|Gammaproteobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_20865_24 1288826.MSNKSG1_17775 1.22e-61 189.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,467ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_20865_25 1288826.MSNKSG1_17770 6.4e-132 375.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,464IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the polypeptide exit tunnel rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_20865_26 1288826.MSNKSG1_17765 8.41e-147 414.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,465E3@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_6844_1 349124.Hhal_1108 2.87e-111 336.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales 135613|Chromatiales G PFAM glycoside hydrolase, family 77 - - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_14593_1 1385935.N836_25680 4.26e-05 54.3 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales 1117|Cyanobacteria T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - HAMP,HATPase_c,HisKA,Response_reg,dCache_1 k141_4067_1 443152.MDG893_01230 2.1e-58 191.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,4640G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the DegT DnrJ EryC1 family spsC - - - - - - - - - - - DegT_DnrJ_EryC1 k141_4067_2 225937.HP15_2397 6.45e-124 368.0 COG0667@1|root,COG1861@1|root,COG0667@2|Bacteria,COG1861@2|Bacteria,1RC4U@1224|Proteobacteria,1S6AT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red,CTP_transf_3 k141_20867_1 1307761.L21SP2_0429 3.2e-59 206.0 COG5001@1|root,COG5001@2|Bacteria,2J5Z5@203691|Spirochaetes 203691|Spirochaetes T Diguanylate cyclase (GGDEF) domain - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_9 k141_14594_1 1278309.KB907100_gene1816 4.27e-143 417.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XH5P@135619|Oceanospirillales 135619|Oceanospirillales M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_6845_1 1122947.FR7_3720 2.46e-17 81.6 COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes 1239|Firmicutes S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_20089_1 1288826.MSNKSG1_08558 1.63e-21 91.3 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,465CV@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein C gspC GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - PDZ_2,T2SSC k141_20089_2 1288826.MSNKSG1_08563 3.92e-175 489.0 28P9W@1|root,2ZC38@2|Bacteria,1RCAP@1224|Proteobacteria,1S3DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type II secretion system (T2SS), protein N - - - ko:K02463 ko05111,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSN k141_20089_3 1288826.MSNKSG1_08568 0.0 992.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4647Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_15297_2 2340.JV46_28020 2.67e-08 56.2 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1J6RI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) - - 2.7.7.6 ko:K00960,ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_15298_1 314256.OG2516_11246 4.02e-48 167.0 COG0477@1|root,COG2814@2|Bacteria,1QUD1@1224|Proteobacteria,2TWB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_20149_1 713586.KB900536_gene2316 1.06e-54 182.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria 1236|Gammaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_6921_1 1535422.ND16A_0370 2.48e-189 547.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,2Q5VE@267889|Colwelliaceae 1236|Gammaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain narB - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_20150_1 595494.Tola_2945 8.53e-72 224.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1Y4P3@135624|Aeromonadales 135624|Aeromonadales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - - - - - - - - - - LGT k141_20150_2 485913.Krac_10872 2.06e-13 71.2 COG5002@1|root,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9 k141_6923_1 2340.JV46_23950 9.22e-46 157.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RRJV@1236|Gammaproteobacteria,1J8XT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_6925_2 1120977.JHUX01000003_gene1736 1.59e-35 132.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,3NIFT@468|Moraxellaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_4112_3 631362.Thi970DRAFT_02190 7.24e-58 209.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,1WW0P@135613|Chromatiales 135613|Chromatiales T TIGRFAM Diguanylate cyclase - - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_4112_4 349124.Hhal_2393 6.38e-87 267.0 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1S296@1236|Gammaproteobacteria,1X2D7@135613|Chromatiales 135613|Chromatiales L Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos k141_4113_1 1385515.N791_00705 2.76e-59 203.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1X3ZE@135614|Xanthomonadales 135614|Xanthomonadales KL Helicase yoaA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,ResIII k141_9728_1 264730.PSPPH_0677 1.88e-50 165.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1Z71J@136849|Pseudomonas syringae group 1236|Gammaproteobacteria O OsmC-like protein yhfA - - ko:K07397 - - - - ko00000 - - - OsmC k141_9728_2 1123368.AUIS01000011_gene1180 4.15e-160 473.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_4114_1 1123279.ATUS01000001_gene941 1.5e-56 189.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1J4MK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_6926_2 187272.Mlg_2496 1.24e-183 536.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales 135613|Chromatiales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_11828_1 1123368.AUIS01000003_gene1613 5.2e-138 407.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2NCE3@225057|Acidithiobacillales 225057|Acidithiobacillales T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat k141_11828_3 398579.Spea_1773 5.97e-140 452.0 COG1361@1|root,COG1361@2|Bacteria,1MUQC@1224|Proteobacteria,1RYHS@1236|Gammaproteobacteria,2QEK3@267890|Shewanellaceae 1236|Gammaproteobacteria M Gametolysin peptidase M11 - - - - - - - - - - - - NPCBM_assoc,Peptidase_M11 k141_4115_2 1121374.KB891576_gene512 5.63e-22 95.9 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_11829_1 754477.Q7C_130 3.46e-36 132.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,4607C@72273|Thiotrichales 72273|Thiotrichales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_11829_2 1249627.D779_2734 2.08e-28 112.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WXIX@135613|Chromatiales 135613|Chromatiales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_9729_1 323261.Noc_2706 1.29e-96 308.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales 135613|Chromatiales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA - 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_6927_1 396588.Tgr7_0247 2.4e-68 213.0 COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria,1X0WB@135613|Chromatiales 135613|Chromatiales J PFAM Cold-shock protein, DNA-binding - - - - - - - - - - - - CSD,Ribosomal_S30AE k141_11830_1 2340.JV46_15090 5.25e-110 330.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1J4X6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Adenylsucc_synt k141_11830_2 1452718.JBOY01000151_gene3356 1.35e-15 77.4 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_9731_1 998674.ATTE01000001_gene4327 4.69e-73 230.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,4606V@72273|Thiotrichales 72273|Thiotrichales E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_6928_2 396595.TK90_1182 1.78e-86 263.0 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1WXRP@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_6929_3 1260251.SPISAL_03535 4.32e-18 84.7 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1WW51@135613|Chromatiales 135613|Chromatiales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_9876_2 338963.Pcar_3086 3.81e-84 258.0 COG2197@1|root,COG2197@2|Bacteria,1PHR7@1224|Proteobacteria,42UJB@68525|delta/epsilon subdivisions,2WQPN@28221|Deltaproteobacteria,43SQ2@69541|Desulfuromonadales 28221|Deltaproteobacteria KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - Response_reg k141_4330_1 1124780.ANNU01000064_gene450 1.15e-12 74.3 COG3291@1|root,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia 976|Bacteroidetes E C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD k141_21111_1 1408419.JHYG01000007_gene2938 2.78e-17 75.5 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,2UFFI@28211|Alphaproteobacteria,2JUQD@204441|Rhodospirillales 204441|Rhodospirillales S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_21111_2 1278309.KB907099_gene2785 1.25e-215 600.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1XH8M@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_21111_3 1278309.KB907099_gene2784 1.64e-68 208.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XJX9@135619|Oceanospirillales 135619|Oceanospirillales J endoribonuclease - - - - - - - - - - - - Ribonuc_L-PSP k141_16877_1 291112.PAU_02082 1.26e-26 104.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_16877_2 395493.BegalDRAFT_1798 4.73e-34 127.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,460FI@72273|Thiotrichales 72273|Thiotrichales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16 k141_4990_1 314262.MED193_21284 5.31e-291 806.0 COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,1MV6I@1224|Proteobacteria,2TTWN@28211|Alphaproteobacteria,2P2T4@2433|Roseobacter 28211|Alphaproteobacteria H pfkB family carbohydrate kinase iolC - 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DUF2090,PfkB k141_10617_1 999541.bgla_1g25400 1.54e-35 124.0 COG4680@1|root,COG4680@2|Bacteria,1N1N1@1224|Proteobacteria 1224|Proteobacteria S regulation of mRNA catabolic process higB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1903311,GO:2000112,GO:2000113 - ko:K19166 - - - - ko00000,ko01000,ko02048 - - - HigB_toxin k141_1531_1 981327.F925_01014 1.58e-38 147.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,3NJI2@468|Moraxellaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_14090_1 555088.DealDRAFT_1751 4.61e-38 142.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1UM4E@1239|Firmicutes,25GAM@186801|Clostridia,42KR9@68298|Syntrophomonadaceae 186801|Clostridia M glycosyl transferase group 1 - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glycos_transf_1,Sucrose_synth k141_7115_1 545276.KB898724_gene1850 1.95e-163 490.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_19656_1 944435.AXAJ01000019_gene5264 2.6e-80 244.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_7830_1 323261.Noc_2631 1.57e-41 145.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_7830_2 159087.Daro_0289 1.65e-21 87.4 COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,2KWZM@206389|Rhodocyclales 206389|Rhodocyclales S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 k141_7830_3 713586.KB900536_gene2648 3.53e-71 219.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1WX46@135613|Chromatiales 135613|Chromatiales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_9184_1 589865.DaAHT2_1649 1.65e-24 101.0 COG0561@1|root,COG0561@2|Bacteria,1QFFG@1224|Proteobacteria,42R6U@68525|delta/epsilon subdivisions,2WN0Q@28221|Deltaproteobacteria,2MMQ9@213118|Desulfobacterales 28221|Deltaproteobacteria S HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP k141_9184_2 555088.DealDRAFT_1751 1.13e-106 334.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1UM4E@1239|Firmicutes,25GAM@186801|Clostridia,42KR9@68298|Syntrophomonadaceae 186801|Clostridia M glycosyl transferase group 1 - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glycos_transf_1,Sucrose_synth k141_2226_1 555778.Hneap_1910 2.27e-94 296.0 COG1215@1|root,COG4671@1|root,COG1215@2|Bacteria,COG4671@2|Bacteria,1QU2M@1224|Proteobacteria,1SCHV@1236|Gammaproteobacteria,1X2RE@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_14800_1 765913.ThidrDRAFT_2551 3.56e-10 60.8 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales 135613|Chromatiales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_6404_1 1288826.MSNKSG1_00928 4.18e-256 712.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_12692_1 743721.Psesu_0338 1.09e-113 343.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1X4FV@135614|Xanthomonadales 135614|Xanthomonadales C IG-like fold at C-terminal of FixG, putative oxidoreductase - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_18975_1 97139.C824_00570 7.86e-33 120.0 COG1943@1|root,COG1943@2|Bacteria,1V53Y@1239|Firmicutes,25CMQ@186801|Clostridia,36VU7@31979|Clostridiaceae 186801|Clostridia L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp k141_4991_1 1120963.KB894505_gene3717 2.32e-74 231.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,2Q28D@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Outer membrane lipoprotein-sorting protein VP1287 - - - - - - - - - - - LolA_like k141_5751_1 1476876.JOJO01000015_gene6174 4.23e-79 251.0 COG0465@1|root,COG0465@2|Bacteria,2I2U8@201174|Actinobacteria 201174|Actinobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41,TPR_19,TPR_20 k141_845_1 1163617.SCD_n00699 6.78e-32 115.0 COG0355@1|root,COG0355@2|Bacteria,1RKXG@1224|Proteobacteria,2VR54@28216|Betaproteobacteria 28216|Betaproteobacteria C ATP synthase, Delta/Epsilon chain, beta-sandwich domain - - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_845_2 261292.Nit79A3_0040 6.47e-50 161.0 2CBNW@1|root,32RTR@2|Bacteria,1N7RB@1224|Proteobacteria,2VVDG@28216|Betaproteobacteria,374NX@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_845_3 1163617.SCD_n00697 3.66e-25 97.8 2E6XU@1|root,331H5@2|Bacteria,1N0RI@1224|Proteobacteria,2VUYX@28216|Betaproteobacteria 28216|Betaproteobacteria S N-ATPase, AtpR subunit - - - - - - - - - - - - AtpR k141_845_4 261292.Nit79A3_0042 2.25e-122 353.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VNK8@28216|Betaproteobacteria,3725X@32003|Nitrosomonadales 28216|Betaproteobacteria C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_845_5 1208321.D104_14555 9.32e-10 55.5 COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria,1XKFI@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_14091_1 1123269.NX02_06615 3.59e-57 193.0 COG0210@1|root,COG0210@2|Bacteria,1R3YI@1224|Proteobacteria,2U0RP@28211|Alphaproteobacteria,2K5SB@204457|Sphingomonadales 204457|Sphingomonadales L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_17560_1 1278309.KB907099_gene2853 1.61e-249 705.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XIC7@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_9877_2 1306406.ASHX01000001_gene4342 5.59e-14 72.8 COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria 201174|Actinobacteria S glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_6405_1 1049564.TevJSym_aq00400 1.74e-73 229.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 ATP-synt_A k141_3637_2 485915.Dret_2002 1.08e-189 538.0 COG3464@1|root,COG3464@2|Bacteria,1R4DH@1224|Proteobacteria,43AQ4@68525|delta/epsilon subdivisions,2X63W@28221|Deltaproteobacteria,2MGXP@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - - - - - - - - - - DDE_Tnp_ISL3,zf-ISL3 k141_113_1 1288826.MSNKSG1_04676 3.33e-227 640.0 COG4716@1|root,COG4716@2|Bacteria,1MVTV@1224|Proteobacteria,1RQMG@1236|Gammaproteobacteria,469F5@72275|Alteromonadaceae 1236|Gammaproteobacteria S MCRA family mycA - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA k141_2933_1 396588.Tgr7_2186 8.62e-157 446.0 COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria,1WWM7@135613|Chromatiales 135613|Chromatiales C reductase, dissimilatory-type beta subunit dsrB - 1.8.99.5 ko:K11181 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_5752_1 292415.Tbd_0387 6.12e-19 84.7 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,1KRHN@119069|Hydrogenophilales 119069|Hydrogenophilales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_5752_2 1127673.GLIP_0887 1.08e-32 119.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,466F7@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_18262_1 1278309.KB907099_gene2774 1.33e-253 702.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI11@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18262_2 1278309.KB907099_gene2773 1.86e-254 702.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,1XHZR@135619|Oceanospirillales 135619|Oceanospirillales C L-carnitine dehydratase bile acid-inducible protein F - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 k141_18262_3 1278309.KB907099_gene2772 1.36e-287 785.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1XI9Y@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_16160_1 1288826.MSNKSG1_12512 8.44e-199 554.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_17561_1 1237149.C900_05121 3.32e-16 81.6 2ECXC@1|root,336UI@2|Bacteria,4NV8T@976|Bacteroidetes,47RWP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_4993_1 388401.RB2150_00619 2.14e-50 163.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,3ZHHY@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, periplasmic component mlaD - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_4993_2 1530186.JQEY01000003_gene2267 3.67e-08 54.7 COG4765@1|root,COG4765@2|Bacteria,1RHI7@1224|Proteobacteria,2UBR9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF2155 k141_10619_1 1123393.KB891317_gene2287 1.54e-97 290.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,1KRAJ@119069|Hydrogenophilales 119069|Hydrogenophilales J Metallopeptidase family M24 map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_10619_2 95619.PM1_0217265 4.09e-16 80.5 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_7117_1 472759.Nhal_2748 7.43e-131 390.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_1533_2 1123518.ARWI01000001_gene54 1.71e-60 200.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,4604B@72273|Thiotrichales 72273|Thiotrichales C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_21724_1 1026882.MAMP_01069 0.0 1665.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales 72273|Thiotrichales E Vitamin B12 dependent methionine synthase, activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_21724_2 1121921.KB898710_gene652 2.77e-19 85.9 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the MtfA family mtfA GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_114_1 1122134.KB893651_gene2087 7.71e-06 45.8 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XKU7@135619|Oceanospirillales 135619|Oceanospirillales I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_114_2 631362.Thi970DRAFT_02910 2.49e-77 238.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales 135613|Chromatiales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_3638_1 987059.RBXJA2T_09722 1.39e-39 140.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KK41@119065|unclassified Burkholderiales 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_3638_2 1163617.SCD_n00928 2.29e-65 207.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_16879_1 1123401.JHYQ01000002_gene2806 3.11e-104 315.0 COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,1RRKZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 k141_16879_2 1123368.AUIS01000003_gene1816 2.07e-45 162.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,2NBV2@225057|Acidithiobacillales 1236|Gammaproteobacteria O Peptidase family M48 htpX GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_19658_1 396588.Tgr7_3082 1.35e-176 498.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQPA@1236|Gammaproteobacteria,1X2CQ@135613|Chromatiales 135613|Chromatiales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_15516_1 1335757.SPICUR_00460 2.3e-63 216.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1WX02@135613|Chromatiales 135613|Chromatiales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_15516_2 765914.ThisiDRAFT_1039 1.63e-223 639.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_18263_1 349102.Rsph17025_1108 5.72e-76 238.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2TR6P@28211|Alphaproteobacteria,1FB66@1060|Rhodobacter 28211|Alphaproteobacteria P extracellular solute-binding protein futA1 - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 k141_18263_2 935848.JAEN01000011_gene1840 0.000588 42.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2PUTC@265|Paracoccus 28211|Alphaproteobacteria S MazG nucleotide pyrophosphohydrolase domain mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG k141_20395_1 1232683.ADIMK_0867 7.2e-42 154.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_20395_2 105559.Nwat_2073 1.46e-111 330.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales 135613|Chromatiales BQ PFAM histone deacetylase superfamily - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl k141_14093_1 1123518.ARWI01000001_gene1635 6.62e-44 160.0 COG2010@1|root,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,1T01Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Peripla_BP_6 k141_14096_1 999411.HMPREF1092_00662 5.25e-05 45.1 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,36DN7@31979|Clostridiaceae 186801|Clostridia F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA2 - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_11327_1 1288826.MSNKSG1_14037 1.07e-44 152.0 COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,1RNSM@1236|Gammaproteobacteria,466Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily pagO - - - - - - - - - - - EamA k141_11327_2 1288826.MSNKSG1_14032 4.08e-247 679.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1T05M@1236|Gammaproteobacteria,468T9@72275|Alteromonadaceae 1236|Gammaproteobacteria P transport protein CorA corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_11327_3 1288826.MSNKSG1_14027 9.72e-136 384.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,4645P@72275|Alteromonadaceae 1236|Gammaproteobacteria O Alkyl hydroperoxide reductase ahpC GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_11327_4 1288826.MSNKSG1_14022 2.13e-169 473.0 2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S3VD@1236|Gammaproteobacteria,467A6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3581) SO4011 - - - - - - - - - - - DUF3581 k141_11327_5 1288826.MSNKSG1_14017 0.0 994.0 COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,465DW@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3634 Alkyl hydroperoxide reductase, large subunit ahpF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_11327_6 1288826.MSNKSG1_14012 3.3e-159 450.0 2EH7J@1|root,33ZUS@2|Bacteria,1NYEC@1224|Proteobacteria,1SQW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial extracellular solute-binding proteins, family 3 - - - - - - - - - - - - SBP_bac_3 k141_11327_7 1288826.MSNKSG1_14007 4.84e-150 422.0 COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,1S4S3@1236|Gammaproteobacteria,466HK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Cysteine - - - - - - - - - - - - Transglut_core k141_11327_8 1288826.MSNKSG1_14002 4.1e-249 683.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPCH@1236|Gammaproteobacteria 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein aphA - - - - - - - - - - - Hist_deacetyl k141_11327_9 1288826.MSNKSG1_13997 3.36e-98 289.0 28NVI@1|root,2ZBTK@2|Bacteria,1N283@1224|Proteobacteria,1S26U@1236|Gammaproteobacteria,467GW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial inner membrane protein - - - - - - - - - - - - Imp-YgjV k141_21726_1 1278309.KB907100_gene2086 4.58e-135 399.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XII4@135619|Oceanospirillales 135619|Oceanospirillales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_21726_2 1278309.KB907100_gene2085 2.72e-302 829.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XHK9@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k141_21726_3 1278309.KB907100_gene2083 5.78e-72 224.0 COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,1RQYV@1236|Gammaproteobacteria,1XIDK@135619|Oceanospirillales 135619|Oceanospirillales C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_11357_2 511062.GU3_14310 1.35e-137 402.0 COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,1RNNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C FAD linked oxidase domain protein - - 1.17.99.1 ko:K05797 ko00623,ko01100,ko01120,map00623,map01100,map01120 - R02675,R11194 RC00769 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_21131_1 999547.KI421500_gene3452 6.33e-15 72.8 COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,27ZEC@191028|Leisingera 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_3 k141_21131_2 1353529.M899_2891 8.04e-43 149.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 k141_9889_1 1504672.669784443 3.68e-84 278.0 COG3203@1|root,COG3203@2|Bacteria,1QVSG@1224|Proteobacteria 1224|Proteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane VPA1441 - - - - - - - - - - - - k141_4506_3 1278309.KB907105_gene1510 1.07e-119 343.0 COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,1XJC2@135619|Oceanospirillales 135619|Oceanospirillales J Elongation factor P - - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_4506_4 1278309.KB907105_gene1511 7.13e-26 104.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1XJH2@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the GcvT family - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_10022_1 498211.CJA_1933 1.72e-44 154.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1FGJX@10|Cellvibrio 1236|Gammaproteobacteria NT Methyltransferase, chemotaxis proteins cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_10022_2 1268239.PALB_6220 5.04e-29 109.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,2Q2NT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_2372_1 439496.RBY4I_2405 1.35e-86 272.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_298_1 1449351.RISW2_13480 9.66e-57 181.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,4KMGT@93682|Roseivivax 28211|Alphaproteobacteria S Yqey-like protein MA20_04985 - - ko:K09117 - - - - ko00000 - - - YqeY k141_997_1 1122599.AUGR01000002_gene3358 5.7e-55 187.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XNV7@135619|Oceanospirillales 135619|Oceanospirillales P Na+/H+ antiporter 1 - - - - - - - - - - - - Na_H_antiport_1 k141_10785_1 287.DR97_4281 2.06e-93 300.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1YEYT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_21922_1 983545.Glaag_0244 1.21e-24 95.1 2ENSD@1|root,33GDJ@2|Bacteria,1NGWW@1224|Proteobacteria,1SW0W@1236|Gammaproteobacteria,46CC2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21922_2 155864.EDL933_1467 1.22e-13 72.8 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,3XNAK@561|Escherichia 1236|Gammaproteobacteria IQ 3-oxoacyl- acyl-carrier-protein reductase - - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 ko:K00059,ko:K18337 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 M00083,M00572 R03942,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10788,R10995,R11671 RC00029,RC00066,RC00117,RC00161 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_21256_1 472759.Nhal_0548 2.34e-50 174.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_21256_2 870187.Thini_3907 2.32e-19 85.9 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,460VX@72273|Thiotrichales 72273|Thiotrichales S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_17749_1 1278309.KB907099_gene2787 9.16e-40 136.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,1XJYH@135619|Oceanospirillales 135619|Oceanospirillales K L-2,4-diaminobutyric acid acetyltransferase ectA - 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_17749_2 1278309.KB907099_gene2786 1.09e-89 265.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XK3K@135619|Oceanospirillales 135619|Oceanospirillales K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_17749_3 1278309.KB907101_gene319 1.02e-135 390.0 2C09D@1|root,2Z7WQ@2|Bacteria,1QRHA@1224|Proteobacteria,1S0GY@1236|Gammaproteobacteria,1XJG6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_17749_4 1278309.KB907101_gene318 2.2e-138 392.0 28I9E@1|root,2Z8C2@2|Bacteria,1RBP7@1224|Proteobacteria,1S2SQ@1236|Gammaproteobacteria,1XJAF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_17749_6 1278309.KB907101_gene316 2.76e-53 174.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1XH28@135619|Oceanospirillales 135619|Oceanospirillales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_8022_1 1249627.D779_2215 1e-46 162.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1WWQD@135613|Chromatiales 135613|Chromatiales H Belongs to the folylpolyglutamate synthase family - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M k141_8022_2 95619.PM1_0209720 5.21e-130 376.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Carboxyl_trans k141_12858_1 1278309.KB907111_gene3385 2.69e-196 579.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF k141_12858_2 722419.PH505_ac00860 8.51e-63 206.0 COG0179@1|root,COG0179@2|Bacteria,1MW82@1224|Proteobacteria,1RQYW@1236|Gammaproteobacteria,2Q095@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) fahA - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_4620 FAA_hydrolase,FAA_hydrolase_N k141_5157_1 396588.Tgr7_2560 4.29e-22 95.5 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1WXCQ@135613|Chromatiales 135613|Chromatiales P PFAM NnrS family protein - - - ko:K07234 - - - - ko00000 - - - NnrS k141_5157_2 1123517.JOMR01000001_gene1151 1.02e-42 152.0 COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1RPW5@1236|Gammaproteobacteria,46151@72273|Thiotrichales 72273|Thiotrichales H PFAM UbiA prenyltransferase - - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_16293_1 1000565.METUNv1_02945 1.74e-47 157.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales 206389|Rhodocyclales S CoA-binding protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 k141_16293_2 765911.Thivi_2387 1.24e-61 199.0 COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1SZC2@1236|Gammaproteobacteria,1X2EH@135613|Chromatiales 135613|Chromatiales Q PFAM methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_16293_3 743720.Psefu_0382 4.89e-149 431.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1YV1K@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_998_2 1278309.KB907101_gene812 2.77e-35 121.0 2BYTD@1|root,33P98@2|Bacteria,1NHI8@1224|Proteobacteria,1SJ15@1236|Gammaproteobacteria,1XMPZ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11463_2 1123393.KB891333_gene2621 4.05e-27 100.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria 1224|Proteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_4507_1 1163407.UU7_04312 1.76e-58 199.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1X3TH@135614|Xanthomonadales 135614|Xanthomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_3120_2 1122194.AUHU01000003_gene2286 1.63e-120 370.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,4648I@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpV - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_19797_1 1002340.AFCF01000073_gene3455 2.41e-78 245.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,34F3W@302485|Phaeobacter 28211|Alphaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_1719_1 1442599.JAAN01000021_gene2269 2.34e-23 103.0 COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria,1X40J@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_1719_2 1187848.AJYQ01000156_gene3796 4.36e-22 89.7 COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1SE7V@1236|Gammaproteobacteria,1XY08@135623|Vibrionales 135623|Vibrionales T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS,STAS_2 k141_1719_3 1109445.AGSX01000070_gene70 1.6e-31 125.0 COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,1Z0DD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver rsbU - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_20570_1 1232683.ADIMK_1047 1.19e-140 419.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_21923_1 380358.XALC_2528 8.23e-27 114.0 COG2199@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5278@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1X71E@135614|Xanthomonadales 135614|Xanthomonadales T CHASE3 domain - - - - - - - - - - - - CHASE3,GAF_2,GGDEF k141_2373_1 314345.SPV1_03478 2.56e-92 278.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase type 11 arsM - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 k141_15649_6 1165841.SULAR_03053 2.93e-144 414.0 COG2191@1|root,COG2191@2|Bacteria,1NX7R@1224|Proteobacteria,430UJ@68525|delta/epsilon subdivisions 1224|Proteobacteria C FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - - - - - - - - - - FmdE k141_15649_7 1288826.MSNKSG1_13822 1.8e-86 261.0 COG0697@1|root,COG0697@2|Bacteria,1R9B0@1224|Proteobacteria,1RZ6Q@1236|Gammaproteobacteria,466YI@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA k141_10037_1 1202532.FF52_03690 1.18e-15 83.2 COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - CHU_C,DUF11 k141_8671_1 1298608.JCM18900_1463 9.4e-28 107.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,3NMN8@468|Moraxellaceae 1236|Gammaproteobacteria E ABC transporter, ATP-binding protein hisP - 3.6.3.21 ko:K02028,ko:K10017 ko02010,map02010 M00225,M00226,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.1 - - ABC_tran k141_8671_2 1278309.KB907100_gene2171 7.18e-136 405.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1XHXZ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_10799_1 1298867.AUES01000051_gene4506 8.89e-128 392.0 COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria,3K33G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidase, M50 family - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3,PqqD k141_17033_1 391615.ABSJ01000029_gene1940 1.45e-46 172.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1J4IV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_21268_1 765914.ThisiDRAFT_1725 2.19e-180 511.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_21268_2 243233.MCA1475 1.34e-94 300.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales 135618|Methylococcales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_2394_1 95619.PM1_0202825 2.52e-48 175.0 COG1109@1|root,COG4191@1|root,COG1109@2|Bacteria,COG4191@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria 1236|Gammaproteobacteria G phosphomannomutase algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_16315_2 1286106.MPL1_06250 1.95e-56 181.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,460NB@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_21944_2 745411.B3C1_07089 5.89e-25 105.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4Q2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_1737_1 207954.MED92_13863 1.18e-158 461.0 COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XIXX@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K02476 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_8,SPOB_a,sCache_3_2 k141_12177_1 1278309.KB907099_gene2652 8.87e-28 110.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RZJ1@1236|Gammaproteobacteria,1XIDA@135619|Oceanospirillales 135619|Oceanospirillales C Quinohemoprotein amine dehydrogenase - - - - - - - - - - - - Fer4_12,Radical_SAM k141_12177_2 1278309.KB907099_gene2651 1.35e-148 432.0 COG2010@1|root,COG2010@2|Bacteria,1MUF6@1224|Proteobacteria,1RP6Y@1236|Gammaproteobacteria,1XHGM@135619|Oceanospirillales 135619|Oceanospirillales C Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - - - - - - - - - - Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV k141_19814_1 519989.ECTPHS_07331 1.69e-205 602.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales 135613|Chromatiales C Dehydrogenase E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_1006_1 765912.Thimo_3042 2.59e-152 450.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1WW6M@135613|Chromatiales 135613|Chromatiales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_4524_1 768671.ThimaDRAFT_4193 1.31e-72 231.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1WVUM@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_13539_1 644801.Psest_0998 6.75e-50 174.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1Z1MF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_17771_1 643867.Ftrac_0148 1.48e-130 377.0 COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,47M06@768503|Cytophagia 976|Bacteroidetes O Deoxyhypusine synthase dys1 - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS k141_17771_2 1168034.FH5T_01730 3.44e-14 71.2 COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia 976|Bacteroidetes E Pyridoxal-dependent decarboxylase, C-terminal sheet domain speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_6544_1 472759.Nhal_2115 7.48e-42 144.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_17034_2 870967.VIS19158_08358 1.54e-52 182.0 COG0303@1|root,COG1763@1|root,COG0303@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XU88@135623|Vibrionales 135623|Vibrionales H Molybdopterin-guanine dinucleotide biosynthesis protein - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MobB,MoeA_C,MoeA_N k141_12178_1 765913.ThidrDRAFT_2847 2.63e-36 137.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1WW9A@135613|Chromatiales 135613|Chromatiales G PFAM carbohydrate kinase - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_14945_1 765910.MARPU_02410 1.39e-71 230.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_8672_1 1528106.JRJE01000006_gene994 2.83e-20 89.4 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2U5H3@28211|Alphaproteobacteria,2JRS2@204441|Rhodospirillales 204441|Rhodospirillales J Belongs to the pseudouridine synthase RsuA family rluE - 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_8672_2 396588.Tgr7_1841 2.76e-39 135.0 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,1S970@1236|Gammaproteobacteria,1X18A@135613|Chromatiales 135613|Chromatiales F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ - - - - - - - - - - - NUDIX k141_8672_3 402777.KB235903_gene1329 2.18e-12 67.4 COG3322@1|root,COG3852@1|root,COG5001@1|root,COG3322@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1H9V4@1150|Oscillatoriales 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_8042_1 715451.ambt_07575 1.84e-70 239.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_11478_2 1123487.KB892834_gene3022 9.83e-91 273.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KUNU@206389|Rhodocyclales 206389|Rhodocyclales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_3138_1 1288826.MSNKSG1_14197 0.0 1165.0 COG3055@1|root,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria,1RYPR@1236|Gammaproteobacteria,469I9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1929) - - - - - - - - - - - - DUF1929,Kelch_4 k141_3138_2 1288826.MSNKSG1_14192 6.74e-202 563.0 2DQQS@1|root,3384P@2|Bacteria,1NDAV@1224|Proteobacteria,1SG7B@1236|Gammaproteobacteria,46C27@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3138_3 1288826.MSNKSG1_14187 1.46e-237 654.0 28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,1RNKD@1236|Gammaproteobacteria,469PU@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF2157 k141_3138_4 1298593.TOL_0543 7.64e-14 70.9 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,1SDJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - k141_1007_1 1278309.KB907099_gene2822 7.33e-67 211.0 COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1Q5AK@1224|Proteobacteria,1S19Z@1236|Gammaproteobacteria,1XK64@135619|Oceanospirillales 135619|Oceanospirillales K MarR family - - - - - - - - - - - - Acetyltransf_1,MarR,MarR_2 k141_8043_1 1123073.KB899243_gene700 1.36e-61 204.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1X2ZH@135614|Xanthomonadales 135614|Xanthomonadales J Involved in the processing of the 5'end of 16S rRNA rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_12179_1 1288826.MSNKSG1_08608 5.82e-112 327.0 COG2207@1|root,COG2207@2|Bacteria,1R7PM@1224|Proteobacteria,1RYYY@1236|Gammaproteobacteria,46CNV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_3798_1 1278309.KB907102_gene71 3.78e-47 162.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1XH70@135619|Oceanospirillales 135619|Oceanospirillales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_11594_2 1298593.TOL_1190 4.34e-17 84.7 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XJQE@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_7420_1 1535422.ND16A_1815 9.13e-111 332.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 k141_5343_1 1123368.AUIS01000002_gene1534 1.81e-79 264.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,2NBY2@225057|Acidithiobacillales 225057|Acidithiobacillales C Domain of unknown function (DUF3400) - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_1176_1 1434929.X946_3387 7.13e-38 149.0 COG0596@1|root,COG2771@1|root,COG0596@2|Bacteria,COG2771@2|Bacteria,1RGAP@1224|Proteobacteria,2W45X@28216|Betaproteobacteria 28216|Betaproteobacteria K Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 k141_21399_1 511062.GU3_09530 7.88e-51 165.0 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1Y5WJ@135624|Aeromonadales 135624|Aeromonadales S Phosphate-starvation-inducible E - - - ko:K13256 - - - - ko00000 - - - PsiE k141_21399_2 666685.R2APBS1_0735 2.11e-08 53.9 2EJUZ@1|root,33DJM@2|Bacteria,1NIYD@1224|Proteobacteria,1SGV4@1236|Gammaproteobacteria,1X881@135614|Xanthomonadales 135614|Xanthomonadales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_2514_1 1288826.MSNKSG1_11493 6.52e-154 438.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,466XK@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase FAD binding subunit glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_2514_2 1288826.MSNKSG1_11498 0.0 980.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,463YN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 FAD-oxidase_C,FAD_binding_4 k141_2514_3 1288826.MSNKSG1_11503 2.05e-92 270.0 COG3193@1|root,COG3193@2|Bacteria,1RB2H@1224|Proteobacteria,1S5K1@1236|Gammaproteobacteria,468RK@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein, possibly involved in utilization of glycolate and propanediol - - - - - - - - - - - - Haem_degrading k141_2514_5 1288826.MSNKSG1_11513 2.8e-166 465.0 COG4665@1|root,COG4665@2|Bacteria,1RE14@1224|Proteobacteria,1S582@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - - - - - - - - - - DctQ k141_2514_6 1288826.MSNKSG1_11518 1.01e-249 686.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RY6Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_2514_7 1288826.MSNKSG1_11523 1.2e-171 480.0 COG2186@1|root,COG2186@2|Bacteria,1R8M2@1224|Proteobacteria,1RZIJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional glcC GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K05799,ko:K11474 - - - - ko00000,ko03000 - - - FCD,GntR k141_2514_8 1288826.MSNKSG1_11528 1.06e-180 503.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,464UZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4598 ABC-type histidine transport system, ATPase component aotP - - ko:K10021,ko:K10025 ko02010,map02010 M00231,M00235 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.11,3.A.1.3.5,3.A.1.3.6 - - ABC_tran k141_2514_9 1288826.MSNKSG1_11533 3.41e-179 499.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1RPXK@1236|Gammaproteobacteria,4677F@72275|Alteromonadaceae 1236|Gammaproteobacteria ET Belongs to the bacterial solute-binding protein 3 family artJ - - ko:K02030,ko:K09996,ko:K10014,ko:K10022 ko02010,map02010 M00226,M00229,M00235,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.1,3.A.1.3.11,3.A.1.3.3 - - SBP_bac_3 k141_2514_10 1288826.MSNKSG1_11538 1.5e-166 466.0 COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,467ID@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4215 ABC-type arginine transport system, permease component hisQ GO:0003333,GO:0003674,GO:0005215,GO:0005287,GO:0005290,GO:0005291,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015179,GO:0015238,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044464,GO:0045117,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089709,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1901474,GO:1902475,GO:1903810,GO:1903825,GO:1905039,GO:1990822 - ko:K10016,ko:K10024 ko02010,map02010 M00225,M00226,M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.1,3.A.1.3.11 - iSbBS512_1146.SbBS512_E2686 BPD_transp_1 k141_2514_11 1288826.MSNKSG1_11543 1.6e-49 162.0 COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,46750@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4160 ABC-type arginine histidine transport system, permease component aotM - - ko:K10023 ko02010,map02010 M00235 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.11 - - BPD_transp_1 k141_10193_1 1056820.KB900696_gene4101 1.38e-34 120.0 COG5460@1|root,COG5460@2|Bacteria,1N7MS@1224|Proteobacteria,1SCTR@1236|Gammaproteobacteria,2PP05@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Uncharacterized conserved protein (DUF2164) - - - - - - - - - - - - DUF2164 k141_14340_1 519989.ECTPHS_12788 5.12e-60 194.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1WVWE@135613|Chromatiales 135613|Chromatiales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_4659_1 1423144.Gal_00450 1.37e-09 63.9 28H9Q@1|root,2Z7MC@2|Bacteria,1N3UI@1224|Proteobacteria,2TTXB@28211|Alphaproteobacteria,34E68@302485|Phaeobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_7421_1 1462526.BN990_03120 3.19e-32 124.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,4C4N9@84406|Virgibacillus 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_1177_1 859657.RPSI07_1797 6.85e-20 94.7 COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,2VSAM@28216|Betaproteobacteria,1K6NQ@119060|Burkholderiaceae 28216|Betaproteobacteria G Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Lactonase k141_13036_1 1286631.X805_07000 7.69e-16 77.8 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria 1224|Proteobacteria NU type IV pilus modification protein PilV pilV - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_17158_1 2340.JV46_03520 6.39e-216 602.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1J4P4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the phosphoglycerate kinase family pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSbBS512_1146.SbBS512_E3351 PGK k141_15061_1 349521.HCH_05171 2.39e-16 77.4 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1XIKW@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_15061_2 981223.AIED01000049_gene1385 7.43e-46 152.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,3NIIC@468|Moraxellaceae 1236|Gammaproteobacteria A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_13721_1 1303518.CCALI_00158 3.66e-79 253.0 COG0166@1|root,COG0166@2|Bacteria 2|Bacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_7422_1 395493.BegalDRAFT_1677 8.64e-72 237.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent Clp protease ATP-binding subunit ClpA - - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_4660_2 1168067.JAGP01000001_gene1404 1.98e-47 154.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,4618R@72273|Thiotrichales 72273|Thiotrichales J RNA-binding protein - - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_10931_1 1288826.MSNKSG1_00101 9.61e-152 431.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_10931_2 1288826.MSNKSG1_00106 3.07e-77 231.0 COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,468WU@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_10931_3 1288826.MSNKSG1_00111 0.0 1119.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,4650A@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PBP_dimer,Transpeptidase k141_10931_4 1288826.MSNKSG1_00116 0.0 953.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,465IN@72275|Alteromonadaceae 1236|Gammaproteobacteria M acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10931_5 1288826.MSNKSG1_00121 2.3e-309 846.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,464UU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10931_6 1288826.MSNKSG1_00126 6.07e-251 689.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,465NF@72275|Alteromonadaceae 1236|Gammaproteobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Glycos_transf_4,MraY_sig1 k141_10931_7 1288826.MSNKSG1_00131 3.3e-314 857.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,465HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M k141_10931_8 1288826.MSNKSG1_00136 3.01e-214 596.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,4645C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell division ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_16453_1 399795.CtesDRAFT_PD2249 2.25e-59 209.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,4AD7T@80864|Comamonadaceae 28216|Betaproteobacteria T Diguanylate cyclase - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - 7TMR-DISM_7TM,DUF2222,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9 k141_13037_1 485916.Dtox_1442 1.15e-37 144.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,24FM2@186801|Clostridia 186801|Clostridia L PFAM Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_7423_1 279238.Saro_1668 3.28e-56 187.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,2K00Q@204457|Sphingomonadales 204457|Sphingomonadales C belongs to the aldehyde dehydrogenase family ligV - - - - - - - - - - - Aldedh k141_7423_2 279238.Saro_1669 5.06e-20 87.0 COG1024@1|root,COG1024@2|Bacteria,1MVB1@1224|Proteobacteria,2TVK3@28211|Alphaproteobacteria,2K2WS@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA ferB - 4.1.2.41,4.2.1.101 ko:K18383 ko00360,ko01100,ko01110,map00360,map01100,map01110 - R05772,R05773 RC00307,RC01468,RC01828 ko00000,ko00001,ko01000 - - - ECH_1 k141_8178_1 399739.Pmen_2650 2.28e-21 96.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YD64@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_8178_2 395493.BegalDRAFT_0243 3.71e-56 193.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,463SR@72273|Thiotrichales 72273|Thiotrichales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_18556_1 1238184.CM001792_gene2985 1.06e-25 110.0 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,23IZ2@182709|Oceanobacillus 91061|Bacilli C 4Fe-4S dicluster domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 k141_6669_2 388051.AUFE01000003_gene721 4.29e-08 55.5 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU6J@28216|Betaproteobacteria,1K3PA@119060|Burkholderiaceae 28216|Betaproteobacteria H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_5345_1 1323663.AROI01000009_gene3793 1.88e-97 300.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin 4 family protein ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_19930_1 506534.Rhein_3578 4.4e-98 298.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1WZAN@135613|Chromatiales 135613|Chromatiales L PFAM transposase IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_17159_1 1267005.KB911259_gene3815 2.41e-18 84.3 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,3N82T@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_466_1 631362.Thi970DRAFT_04260 0.000693 43.1 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales 135613|Chromatiales U PFAM Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_466_2 1232683.ADIMK_2161 2.1e-71 229.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1S2ZN@1236|Gammaproteobacteria,46AVC@72275|Alteromonadaceae 1236|Gammaproteobacteria U MotA/TolQ/ExbB proton channel family exbB2 - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_466_4 425104.Ssed_1775 1.32e-64 198.0 COG3631@1|root,COG3631@2|Bacteria,1RJ29@1224|Proteobacteria,1S6S3@1236|Gammaproteobacteria,2QC9V@267890|Shewanellaceae 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_466_5 634500.EbC_02890 2.08e-50 172.0 COG2188@1|root,COG2188@2|Bacteria,1R4PN@1224|Proteobacteria,1RQ87@1236|Gammaproteobacteria,3X7A9@551|Erwinia 1236|Gammaproteobacteria K UTRA phnR - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_466_6 1042375.AFPL01000035_gene2843 7.84e-199 559.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RNNI@1236|Gammaproteobacteria,469DU@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW GO:0003674,GO:0003824 2.6.1.112,2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839,ko:K03430 ko00230,ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R04152,R10908 RC00006,RC00008,RC00018,RC00062,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_466_7 349521.HCH_03084 1.49e-57 188.0 COG0637@1|root,COG0637@2|Bacteria,1MX6B@1224|Proteobacteria,1RQPM@1236|Gammaproteobacteria,1XP0S@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the HAD-like hydrolase superfamily. PhnX family phnX - 3.11.1.1 ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R00747 RC00368 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_4661_1 523791.Kkor_1084 2.04e-16 78.2 COG0204@1|root,COG0204@2|Bacteria,1PDUQ@1224|Proteobacteria,1S51R@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_1844_2 1288826.MSNKSG1_01993 0.0 893.0 COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,1RYKJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the peptidase M17 family - - 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 k141_1844_3 1288826.MSNKSG1_01998 3.98e-229 631.0 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RYDB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx k141_15062_2 1249627.D779_2918 1.47e-64 207.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1WXJR@135613|Chromatiales 135613|Chromatiales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_2516_1 1288826.MSNKSG1_09718 1.63e-230 637.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,464MW@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_17899_1 1535422.ND16A_0195 7.81e-13 70.1 COG4795@1|root,COG4795@2|Bacteria,1N6ZJ@1224|Proteobacteria,1SD3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl k141_17899_2 395495.Lcho_2904 0.00077 46.2 COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,1KMKX@119065|unclassified Burkholderiales 28216|Betaproteobacteria NU Type IV minor pilin ComP, DNA uptake sequence receptor - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_17899_3 1216007.AOPM01000071_gene1565 9.58e-14 70.9 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,2Q30G@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_17899_4 1278309.KB907106_gene1368 3.73e-46 155.0 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria 1224|Proteobacteria NU Tfp pilus assembly protein - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_17899_5 1278309.KB907106_gene1367 2.02e-47 157.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1XMB2@135619|Oceanospirillales 135619|Oceanospirillales NU Type IV minor pilin ComP, DNA uptake sequence receptor - - - - - - - - - - - - ComP_DUS,N_methyl k141_17899_6 1278309.KB907106_gene1366 0.0 937.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XISX@135619|Oceanospirillales 135619|Oceanospirillales NU Tfp pilus assembly protein, tip-associated adhesin PilY1 - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_10932_1 1122614.JHZF01000011_gene1784 1.8e-162 470.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2TSXP@28211|Alphaproteobacteria,2PCCE@252301|Oceanicola 28211|Alphaproteobacteria E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha k141_13039_1 1134474.O59_004307 2.12e-70 231.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RZ3X@1236|Gammaproteobacteria,1FHSJ@10|Cellvibrio 1236|Gammaproteobacteria S protein and some similarities with VgrG protein - - - - - - - - - - - - Phage_GPD k141_3907_1 1123237.Salmuc_02167 1.48e-91 273.0 2E3HM@1|root,32EQI@2|Bacteria,1NGRR@1224|Proteobacteria,2UK11@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_3907_2 1502724.FF80_00712 1.82e-50 164.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2U7B2@28211|Alphaproteobacteria,3N8D4@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K AsnC-type helix-turn-helix domain putR - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_18557_1 472759.Nhal_2258 3.03e-83 261.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1WX2Q@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_3,HlyD_D23,OEP k141_7425_1 1337093.MBE-LCI_0204 1.17e-28 113.0 COG1555@1|root,COG1555@2|Bacteria,1RFDG@1224|Proteobacteria,2UEJG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L photosystem II stabilization - - - - - - - - - - - - - k141_14342_2 203122.Sde_0972 3.96e-44 145.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,467UW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_467_1 768671.ThimaDRAFT_4023 8.98e-48 175.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales 135613|Chromatiales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_1180_1 314345.SPV1_12627 1.13e-66 213.0 COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria 1224|Proteobacteria S PFAM Uncharacterised ACR, YagE family COG1723 - - - - - - - - - - - - DUF155 k141_1180_2 2340.JV46_20200 5.07e-31 119.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_13723_1 76869.PputGB1_0396 9.24e-68 214.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1YXA5@136845|Pseudomonas putida group 1236|Gammaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_0821,iECIAI1_1343.ECIAI1_0813,iECO103_1326.ECO103_0813,iECO111_1330.ECO111_0839,iECO26_1355.ECO26_0904,iECSE_1348.ECSE_0831,iECW_1372.ECW_m0833,iEKO11_1354.EKO11_3108,iEcE24377_1341.EcE24377A_0841,iSFV_1184.SFV_0761,iSSON_1240.SSON_0757,iWFL_1372.ECW_m0833,ic_1306.c0858 AAA_26 k141_13723_2 1123073.KB899241_gene2752 7.87e-07 51.2 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1X53I@135614|Xanthomonadales 135614|Xanthomonadales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_17900_2 1026882.MAMP_01683 1.34e-39 140.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,45ZNV@72273|Thiotrichales 72273|Thiotrichales D PFAM CobQ CobB MinD ParA nucleotide binding domain parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,MipZ k141_15063_1 1423144.Gal_00492 1.7e-85 275.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,34E9Q@302485|Phaeobacter 28211|Alphaproteobacteria M Transglycosylase mrcB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_3291_1 521000.PROVRETT_07017 1.01e-68 223.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,3Z8MF@586|Providencia 1236|Gammaproteobacteria H Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_3291_2 1232683.ADIMK_2278 1.68e-83 261.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,464VI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Histidine ammonia-lyase hutH GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic k141_9455_1 998088.B565_2488 7.81e-80 245.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1Y3VI@135624|Aeromonadales 135624|Aeromonadales T helix_turn_helix, Lux Regulon sirA - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_16469_1 1163617.SCD_n02039 3.42e-90 293.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria 28216|Betaproteobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_13061_1 1026882.MAMP_01648 6.15e-85 261.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_13738_1 748658.KB907313_gene2156 8.3e-86 289.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1WXRE@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Response_reg k141_4677_1 1049564.TevJSym_ad01080 7.69e-67 223.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,1J5AV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor oprC - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_10353_1 1265313.HRUBRA_00046 1.49e-29 116.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_10353_2 292415.Tbd_2725 2.71e-32 124.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2VH44@28216|Betaproteobacteria,1KSA1@119069|Hydrogenophilales 119069|Hydrogenophilales E Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_5489_1 157783.LK03_20530 2.16e-121 362.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria 1224|Proteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N k141_8315_1 1278309.KB907100_gene1796 3.59e-158 467.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales 135619|Oceanospirillales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_8315_2 1278309.KB907101_gene511 2.25e-194 543.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,1XHDC@135619|Oceanospirillales 135619|Oceanospirillales O Peptidase family U32 yhbU - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_7551_1 237609.PSAKL28_18300 1.11e-05 55.1 COG4625@1|root,COG4625@2|Bacteria,1R9VZ@1224|Proteobacteria,1SIX9@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Autotransporter beta-domain - - - - - - - - - - - - Autotransporter k141_11073_1 519989.ECTPHS_02134 4.18e-71 228.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WWMQ@135613|Chromatiales 135613|Chromatiales C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_21525_1 748247.AZKH_2097 1.17e-06 50.1 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KXYH@206389|Rhodocyclales 206389|Rhodocyclales T Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,Response_reg k141_21525_2 697282.Mettu_3162 2.29e-168 526.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_15161_1 998674.ATTE01000001_gene2266 1.98e-52 169.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,460EK@72273|Thiotrichales 72273|Thiotrichales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_15161_2 1033802.SSPSH_001095 1.69e-20 87.8 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_13178_2 1237149.C900_01555 1.69e-62 194.0 COG0739@1|root,COG0739@2|Bacteria,4NU35@976|Bacteroidetes 976|Bacteroidetes M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_2660_1 1121875.KB907553_gene20 2.66e-82 259.0 COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_12503_1 1049564.TevJSym_ak00590 2.19e-91 285.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1J5IS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_17296_1 270374.MELB17_14316 2.25e-24 100.0 COG3307@1|root,COG3307@2|Bacteria,1QQRX@1224|Proteobacteria,1RTEK@1236|Gammaproteobacteria,46583@72275|Alteromonadaceae 1236|Gammaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_17296_2 1288826.MSNKSG1_06928 3.01e-105 312.0 COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria,465P7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis gt2M - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_16602_1 713586.KB900536_gene1766 3.85e-41 140.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_16602_2 1331060.RLDS_00465 3.65e-18 84.3 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2U5MT@28211|Alphaproteobacteria,2K417@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_18722_2 1321786.HMPREF1992_01302 3.22e-16 74.3 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes 1239|Firmicutes L GIY-YIG catalytic domain protein yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_18722_3 749222.Nitsa_0227 8.96e-25 99.8 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2YMER@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_1973_1 765912.Thimo_1492 2.7e-26 112.0 COG1527@1|root,COG1527@2|Bacteria,1R7PV@1224|Proteobacteria,1S0C2@1236|Gammaproteobacteria,1WWZK@135613|Chromatiales 135613|Chromatiales C (C AC39) subunit - - - ko:K02119 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - vATP-synt_AC39 k141_15960_1 1123228.AUIH01000003_gene855 6.48e-62 206.0 COG1876@1|root,COG1876@2|Bacteria,1RB64@1224|Proteobacteria,1RRSM@1236|Gammaproteobacteria,1XNHR@135619|Oceanospirillales 135619|Oceanospirillales M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - VanY k141_15960_2 1565129.JSFF01000002_gene3482 3.23e-23 102.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1S3KK@1236|Gammaproteobacteria,2QA0T@267890|Shewanellaceae 1236|Gammaproteobacteria E Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth k141_15960_3 1121935.AQXX01000125_gene822 4.84e-16 73.6 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XJI3@135619|Oceanospirillales 135619|Oceanospirillales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_7552_1 243233.MCA1973 1.08e-42 147.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1XFC3@135618|Methylococcales 135618|Methylococcales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_7552_2 396588.Tgr7_2600 2.09e-17 75.9 COG1993@1|root,COG1993@2|Bacteria,1N8TP@1224|Proteobacteria,1SDYH@1236|Gammaproteobacteria,1WZIY@135613|Chromatiales 135613|Chromatiales S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 k141_5490_2 1026882.MAMP_01036 1.62e-29 118.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,45ZWJ@72273|Thiotrichales 72273|Thiotrichales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_18074_1 1168067.JAGP01000001_gene981 1.62e-37 137.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,460D4@72273|Thiotrichales 72273|Thiotrichales S Cupin superfamily protein - - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_18074_2 55601.VANGNB10_cI1386c 6.32e-36 135.0 COG2199@1|root,COG2199@2|Bacteria,1RDMU@1224|Proteobacteria,1RQC7@1236|Gammaproteobacteria,1XVEI@135623|Vibrionales 135623|Vibrionales T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF k141_22201_1 1288826.MSNKSG1_18450 8e-109 338.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,46514@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_22201_2 1288826.MSNKSG1_18445 1.93e-176 495.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,464EI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ribF family ribF GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0025,iJN746.PP_0602 FAD_syn,Flavokinase k141_17297_1 760154.Sulba_1896 5.03e-95 286.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42MK3@68525|delta/epsilon subdivisions,2YNC9@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M sialic acid synthase - - 2.5.1.56,3.2.1.183 ko:K01654,ko:K08068 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k141_8316_1 1163617.SCD_n02931 1.96e-66 214.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k141_8316_2 765912.Thimo_1749 2.64e-62 202.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_10354_1 270374.MELB17_19721 1.58e-15 80.5 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_10354_2 765911.Thivi_2855 7.75e-43 147.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1WYAC@135613|Chromatiales 135613|Chromatiales NU pilus assembly protein PilP - - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_21526_1 748280.NH8B_0541 5.75e-07 57.4 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar,PTR,Peptidase_S74,Phage_fiber_2 k141_11075_1 686340.Metal_3769 4.39e-15 73.9 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1XEAV@135618|Methylococcales 135618|Methylococcales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_11075_2 472759.Nhal_3945 6.68e-55 176.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k141_8899_4 1288826.MSNKSG1_14157 3.65e-12 64.7 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,4651C@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_1343_1 1237149.C900_04408 5.66e-85 278.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia 976|Bacteroidetes EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_602_1 1123256.KB907931_gene2752 2.05e-20 89.4 COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,1RQ2R@1236|Gammaproteobacteria,1X41X@135614|Xanthomonadales 135614|Xanthomonadales M 3-beta hydroxysteroid dehydrogenase - - - - - - - - - - - - Epimerase k141_5505_2 2340.JV46_08920 1.39e-19 85.9 COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria,1J75E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Dihaem cytochrome c - - - - - - - - - - - - DHC k141_7564_1 1288826.MSNKSG1_14597 3.83e-228 628.0 COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,1RSBY@1236|Gammaproteobacteria,466NI@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ectoine hydroxylase htxA - 1.14.11.55 ko:K10674 ko00260,ko01120,map00260,map01120 - R08050 RC00661 ko00000,ko00001,ko01000 - - - PhyH k141_7564_2 1288826.MSNKSG1_14592 0.0 1212.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,469MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_7564_3 1288826.MSNKSG1_14587 1.85e-122 350.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria,467E1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3833) PP2730 - - - - - - - - - - - DUF3833 k141_7564_4 1288826.MSNKSG1_14582 9.51e-147 423.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_7564_5 1288826.MSNKSG1_14577 0.0 1337.0 COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,1RS9G@1236|Gammaproteobacteria,46ADF@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,dCache_1 k141_7564_6 1288826.MSNKSG1_14572 1.92e-228 633.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,466HH@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_7564_7 1288826.MSNKSG1_14567 0.0 1551.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_21543_1 1278309.KB907106_gene1299 2.67e-50 164.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XIT9@135619|Oceanospirillales 135619|Oceanospirillales E phosphoserine phosphatase - - - - - - - - - - - - HAD k141_21543_2 1278309.KB907106_gene1300 2.1e-118 338.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1XIY0@135619|Oceanospirillales 135619|Oceanospirillales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_21543_3 1278309.KB907106_gene1301 8.74e-85 270.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHCB@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_19435_1 367336.OM2255_09696 2.16e-22 101.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria 28211|Alphaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_11096_1 1417296.U879_01275 2.79e-85 259.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_11096_2 1278309.KB907099_gene2697 7.46e-247 688.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XHUS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_18098_1 266117.Rxyl_1929 4.41e-77 254.0 COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria 201174|Actinobacteria O AAA domain - - - - - - - - - - - - AAA_32,Lon_C k141_4815_1 2340.JV46_08030 2.26e-101 301.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1JA5H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K LysR substrate binding domain oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_3427_1 425104.Ssed_1779 4.19e-71 230.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amino Acid - - - - - - - - - - - - AA_permease_2 k141_8900_1 697282.Mettu_2978 5.59e-35 128.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1XDPP@135618|Methylococcales 135618|Methylococcales O HflC and HflK could regulate a protease - - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_8900_2 317025.Tcr_1090 7.14e-23 100.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_13198_1 1232683.ADIMK_0868 5.73e-16 80.9 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,465RR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_13198_2 1249627.D779_0089 8.63e-38 141.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales 135613|Chromatiales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_18099_1 1137799.GZ78_05670 7.43e-25 100.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_18099_2 203124.Tery_5033 1.63e-05 48.9 COG1073@1|root,COG1073@2|Bacteria,1G2EP@1117|Cyanobacteria,1H83Z@1150|Oscillatoriales 1117|Cyanobacteria S of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4,Peptidase_S9 k141_13879_1 1049564.TevJSym_am00080 2e-81 249.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1J5E4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 AA_kinase,NAT k141_13879_2 1134474.O59_000629 2.59e-63 200.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1FGCW@10|Cellvibrio 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_8901_1 1122137.AQXF01000002_gene300 7.04e-114 343.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_3428_1 491952.Mar181_3330 6.14e-61 190.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1XJJW@135619|Oceanospirillales 135619|Oceanospirillales J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_5507_1 1121405.dsmv_2084 2.65e-12 69.7 COG0535@1|root,COG0535@2|Bacteria,1PNW8@1224|Proteobacteria,42YG5@68525|delta/epsilon subdivisions,2WTXF@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Radical SAM - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM k141_10369_1 365044.Pnap_3977 5.04e-31 115.0 COG1569@1|root,COG1569@2|Bacteria,1RCZE@1224|Proteobacteria,2VMVB@28216|Betaproteobacteria,4AC8P@80864|Comamonadaceae 28216|Betaproteobacteria S PIN domain - - - - - - - - - - - - PIN_3 k141_4009_1 1288826.MSNKSG1_05496 2.96e-210 590.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464D8@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_13199_1 1122137.AQXF01000001_gene2848 8.85e-89 266.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Electron transfer flavoprotein etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K03521 - - - - ko00000 - - - ETF k141_21545_1 1097668.BYI23_B000060 3.36e-48 167.0 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2VKI0@28216|Betaproteobacteria,1K199@119060|Burkholderiaceae 28216|Betaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_6144_3 1278309.KB907101_gene700 3.42e-71 217.0 COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,1SAUP@1236|Gammaproteobacteria,1XMCW@135619|Oceanospirillales 135619|Oceanospirillales S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_6144_4 1278309.KB907101_gene699 1.04e-65 201.0 COG3805@1|root,COG3805@2|Bacteria,1N2DN@1224|Proteobacteria,1SA51@1236|Gammaproteobacteria,1XKNY@135619|Oceanospirillales 135619|Oceanospirillales Q Dopa 45-dioxygenase - - - ko:K10253 - - - - ko00000,ko01000 - - - DOPA_dioxygen k141_7567_1 1232683.ADIMK_4150 1.82e-68 219.0 COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,469FI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridine nucleotide-disulphide oxidoreductase sqr - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_12516_1 1288826.MSNKSG1_18445 4.18e-63 201.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,464EI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ribF family ribF GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0025,iJN746.PP_0602 FAD_syn,Flavokinase k141_12516_2 1288826.MSNKSG1_18440 2.28e-182 519.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,4663F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - iECO103_1326.ECO103_1114 MVIN k141_1345_1 1283300.ATXB01000001_gene35 2.04e-139 416.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XDJY@135618|Methylococcales 135618|Methylococcales E Peptidase family M3 prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_9600_1 1121374.KB891576_gene388 1.21e-145 426.0 28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,1T4JE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1982_2 1026882.MAMP_02816 0.0 942.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales 72273|Thiotrichales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_18740_1 1288826.MSNKSG1_04721 1.07e-197 551.0 COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria 1236|Gammaproteobacteria H belongs to the carbohydrate kinase PfkB family fruK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0008662,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019320,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2168,iAPECO1_1312.APECO1_4386,iB21_1397.B21_02056,iEC042_1314.EC042_2401,iEC55989_1330.EC55989_2421,iECABU_c1320.ECABU_c24990,iECBD_1354.ECBD_1490,iECB_1328.ECB_02097,iECDH10B_1368.ECDH10B_2325,iECDH1ME8569_1439.ECDH1ME8569_2104,iECD_1391.ECD_02097,iECED1_1282.ECED1_2616,iECH74115_1262.ECH74115_3304,iECIAI1_1343.ECIAI1_2248,iECIAI39_1322.ECIAI39_2308,iECNA114_1301.ECNA114_2259,iECO103_1326.ECO103_2643,iECO111_1330.ECO111_2886,iECO26_1355.ECO26_3080,iECOK1_1307.ECOK1_2400,iECP_1309.ECP_2208,iECS88_1305.ECS88_2316,iECSE_1348.ECSE_2436,iECSF_1327.ECSF_2049,iECSP_1301.ECSP_3046,iECUMN_1333.ECUMN_2504,iECW_1372.ECW_m2369,iECs_1301.ECs3060,iEKO11_1354.EKO11_1586,iETEC_1333.ETEC_2303,iEcDH1_1363.EcDH1_1490,iEcHS_1320.EcHS_A2305,iEcSMS35_1347.EcSMS35_2315,iEcolC_1368.EcolC_1480,iG2583_1286.G2583_2711,iJO1366.b2168,iJR904.b2168,iLF82_1304.LF82_0744,iNRG857_1313.NRG857_11005,iPC815.YPO1299,iSBO_1134.SBO_2156,iSDY_1059.SDY_2316,iSFV_1184.SFV_2243,iSF_1195.SF2253,iSFxv_1172.SFxv_2486,iS_1188.S2382,iUMN146_1321.UM146_05955,iUMNK88_1353.UMNK88_2713,iUTI89_1310.UTI89_C2443,iWFL_1372.ECW_m2369,iY75_1357.Y75_RS11345,iZ_1308.Z3426,ic_1306.c2703 PfkB k141_6145_1 1441629.PCH70_43660 1.44e-10 67.8 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1Z5NX@136849|Pseudomonas syringae group 1236|Gammaproteobacteria NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_14477_1 857087.Metme_1678 3.83e-43 153.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1XF1M@135618|Methylococcales 135618|Methylococcales F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_3517_1 1288826.MSNKSG1_09643 0.0 1272.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit phaA - 1.6.5.3 ko:K00341,ko:K05559 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,3.D.1 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_3517_3 1288826.MSNKSG1_09638 0.0 1063.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_12585_1 32042.PstZobell_20473 3.7e-79 259.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1Z1X0@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_5610_1 1163617.SCD_n01183 2.24e-11 64.7 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria 28216|Betaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA k141_5610_2 998088.B565_2275 2.59e-19 87.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1Y3XG@135624|Aeromonadales 135624|Aeromonadales L MgsA AAA+ ATPase C terminal - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_2821_1 96561.Dole_3270 4.69e-39 148.0 COG0642@1|root,COG0834@1|root,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43BSB@68525|delta/epsilon subdivisions,2X735@28221|Deltaproteobacteria 28221|Deltaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - HATPase_c,HisKA,SBP_bac_3 k141_18863_1 29581.BW37_03418 4.07e-65 201.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,4777R@75682|Oxalobacteraceae 28216|Betaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH k141_18863_2 396588.Tgr7_0218 2.06e-53 169.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1WYHH@135613|Chromatiales 135613|Chromatiales E phosphoribosyl-ATP pyrophosphohydrolase hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_18863_3 323261.Noc_3057 4.41e-51 164.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales 135613|Chromatiales FG PFAM Histidine triad (HIT) protein - - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_18863_4 317025.Tcr_1972 2.46e-18 78.6 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,461D2@72273|Thiotrichales 72273|Thiotrichales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_18863_5 1122604.JONR01000010_gene3841 1.35e-17 79.3 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1X84C@135614|Xanthomonadales 135614|Xanthomonadales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_18863_6 765911.Thivi_1914 6.33e-13 69.3 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_740_1 1278309.KB907105_gene1464 1.11e-265 751.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XJ1N@135619|Oceanospirillales 135619|Oceanospirillales Q Paraquat-inducible protein B - - - - - - - - - - - - MlaD k141_19554_1 391612.CY0110_28874 1.65e-65 221.0 COG5001@1|root,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,3KG35@43988|Cyanothece 1117|Cyanobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_9 k141_9098_2 713587.THITH_16390 2.15e-24 103.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k141_12586_1 1049564.TevJSym_av00160 3.23e-84 265.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_20954_1 472759.Nhal_2807 7.59e-78 248.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales 135613|Chromatiales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase k141_7013_1 1288826.MSNKSG1_14897 2.57e-230 640.0 COG2056@1|root,COG2056@2|Bacteria,1N8U2@1224|Proteobacteria,1RRW5@1236|Gammaproteobacteria,469EN@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease - - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - - Na_H_antiport_2,Na_H_antiporter k141_7013_2 1288826.MSNKSG1_14892 9.36e-55 171.0 COG3529@1|root,COG3529@2|Bacteria,1NPXJ@1224|Proteobacteria,1SHB8@1236|Gammaproteobacteria,4696D@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleic-acid-binding protein containing a Zn-ribbon domain - - - ko:K07070 - - - - ko00000 - - - DUF2387 k141_7013_3 1288826.MSNKSG1_14887 0.0 1372.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,4648F@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0339 Zn-dependent oligopeptidases prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_14683_1 187272.Mlg_1486 2e-67 204.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1WYW2@135613|Chromatiales 135613|Chromatiales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4 k141_14683_2 998674.ATTE01000001_gene2814 8.85e-23 99.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales 72273|Thiotrichales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_16767_1 1255043.TVNIR_1763 2.49e-26 105.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1WWMU@135613|Chromatiales 135613|Chromatiales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_16767_2 1137799.GZ78_07160 3.92e-46 150.0 COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,1SA3S@1236|Gammaproteobacteria,1XQMF@135619|Oceanospirillales 135619|Oceanospirillales C Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_3518_1 1033734.CAET01000076_gene2962 1.69e-05 45.8 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus 91061|Bacilli S phosphohydrolase ypgQ - - ko:K06950 - - - - ko00000 - - - HD k141_3518_3 1313301.AUGC01000014_gene2507 2.45e-12 67.4 COG4251@1|root,COG4251@2|Bacteria 2|Bacteria T photoreceptor activity - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12 k141_1426_1 1122197.ATWI01000011_gene437 3.68e-09 57.8 COG0457@1|root,COG0457@2|Bacteria,1REWI@1224|Proteobacteria,1S3PC@1236|Gammaproteobacteria,46AXR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_16 k141_1426_2 1122197.ATWI01000011_gene438 5.2e-46 150.0 2EB2M@1|root,3353D@2|Bacteria,1NDF8@1224|Proteobacteria,1SG64@1236|Gammaproteobacteria,46BEZ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1426_3 1122197.ATWI01000011_gene439 4.06e-98 289.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins - - - - - - - - - - - - MotA_ExbB k141_21639_1 1278309.KB907110_gene3192 9.54e-208 583.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1XHQQ@135619|Oceanospirillales 135619|Oceanospirillales S SpoVR family - - - - - - - - - - - - SpoVR k141_21639_2 1278309.KB907110_gene3193 1.27e-81 241.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XK38@135619|Oceanospirillales 135619|Oceanospirillales FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hinT - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_12587_1 1123247.AUIJ01000006_gene3233 1.03e-87 280.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system large permease component dctM6 - - - - - - - - - - - DctM k141_20263_1 1354303.M917_1897 2.25e-188 536.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,3NIN2@468|Moraxellaceae 1236|Gammaproteobacteria C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_8400_1 1278309.KB907100_gene2037 2.7e-123 354.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,1RMVC@1236|Gammaproteobacteria,1XJGG@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_C_4,GST_N,GST_N_3 k141_8400_2 1278309.KB907100_gene2036 4.78e-161 456.0 COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,1RQ7J@1236|Gammaproteobacteria,1XI5Z@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_5611_1 686578.AFFX01000010_gene2266 3.2e-20 100.0 COG1109@1|root,COG4191@1|root,COG1109@2|Bacteria,COG4191@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria 1236|Gammaproteobacteria G phosphomannomutase algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_9790_1 1163409.UUA_08176 1.95e-163 484.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1X2YZ@135614|Xanthomonadales 135614|Xanthomonadales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_9099_2 1342302.JASC01000014_gene2349 5.9e-101 293.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2TQYR@28211|Alphaproteobacteria,3ZYGW@60136|Sulfitobacter 28211|Alphaproteobacteria P Cyanate lyase C-terminal domain, Cyanate hydratase cynS - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase k141_11203_2 1283300.ATXB01000001_gene1432 6.99e-61 198.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XE6Q@135618|Methylococcales 135618|Methylococcales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_13289_1 1278309.KB907103_gene997 1.62e-158 452.0 COG2199@1|root,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,1S284@1236|Gammaproteobacteria,1XRT4@135619|Oceanospirillales 135619|Oceanospirillales T Protein of unknown function, DUF484 - - - - - - - - - - - - DUF484,GGDEF k141_13289_2 1278309.KB907103_gene996 1.7e-104 304.0 COG3945@1|root,COG3945@2|Bacteria,1RM01@1224|Proteobacteria,1S7CW@1236|Gammaproteobacteria,1XKD0@135619|Oceanospirillales 135619|Oceanospirillales S Pfam Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_13289_3 1278309.KB907103_gene995 3.07e-87 261.0 COG0546@1|root,COG0546@2|Bacteria,1RHAA@1224|Proteobacteria,1S67H@1236|Gammaproteobacteria,1XS5C@135619|Oceanospirillales 135619|Oceanospirillales S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_21640_1 1288826.MSNKSG1_16026 6.06e-145 418.0 2E9Q2@1|root,333WE@2|Bacteria,1N872@1224|Proteobacteria,1SDWG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18158_1 1121935.AQXX01000068_gene5873 9.28e-12 66.6 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1XKB8@135619|Oceanospirillales 135619|Oceanospirillales T Negative regulator of sigma E activity mucB - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_15377_1 1517416.IDAT_10380 4.19e-45 159.0 COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,1S09X@1236|Gammaproteobacteria,2QGNN@267893|Idiomarinaceae 1236|Gammaproteobacteria M Membrane - - - - - - - - - - - - Porin_4 k141_15377_2 1122201.AUAZ01000001_gene2471 9.02e-277 762.0 COG1457@1|root,COG1457@2|Bacteria,1PFQZ@1224|Proteobacteria,1RY9J@1236|Gammaproteobacteria 1236|Gammaproteobacteria F allantoin - - - - - - - - - - - - Transp_cyt_pur k141_1427_1 95619.PM1_0218905 6.4e-50 168.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator IV02_08490 - - - - - - - - - - - HTH_1,LysR_substrate k141_1427_2 261292.Nit79A3_2530 2.98e-50 162.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,2VU3K@28216|Betaproteobacteria,373A4@32003|Nitrosomonadales 28216|Betaproteobacteria S SURF4 family - - - ko:K15977 - - - - ko00000 - - - DoxX k141_19555_1 34506.g5665 2.4e-156 486.0 COG0223@1|root,COG0451@1|root,COG0463@1|root,COG1245@1|root,KOG0063@2759|Eukaryota,KOG1429@2759|Eukaryota,KOG2978@2759|Eukaryota,KOG3082@2759|Eukaryota,39SRK@33154|Opisthokonta,3CPSA@33208|Metazoa,3DE5H@33213|Bilateria 33208|Metazoa GJM Formyl transferase, C-terminal domain - - - - - - - - - - - - Epimerase,Formyl_trans_C,Formyl_trans_N k141_9100_1 394221.Mmar10_2816 1.06e-24 105.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,43WUZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_10487_1 511.JT27_13260 2.15e-08 57.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,3T2CD@506|Alcaligenaceae 28216|Betaproteobacteria L TatD related DNase ycfH - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_10487_2 1278309.KB907100_gene1833 0.0 996.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1XHRK@135619|Oceanospirillales 135619|Oceanospirillales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_13290_1 316056.RPC_2091 7.08e-70 228.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,3JRC0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain MA20_21605 - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 k141_30_1 187272.Mlg_2070 2.25e-50 175.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_20958_1 207954.MED92_12871 6.72e-104 334.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_21641_1 246200.SPO0596 2.3e-77 241.0 COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,2TU6B@28211|Alphaproteobacteria,4NA4K@97050|Ruegeria 28211|Alphaproteobacteria E Alcohol dehydrogenase GroES-like domain yjjN GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034193,GO:0034195,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.14,1.1.1.380 ko:K00008,ko:K08322 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896,R10848 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N k141_11204_1 1279017.AQYJ01000020_gene1329 6.96e-103 301.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,465T7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_11204_2 1121923.GPUN_2576 1.2e-21 93.6 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_5612_2 767434.Fraau_2420 1.74e-06 48.5 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1X453@135614|Xanthomonadales 135614|Xanthomonadales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_9101_1 1123393.KB891316_gene1507 3.99e-70 221.0 COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,2VHKR@28216|Betaproteobacteria,1KSKE@119069|Hydrogenophilales 119069|Hydrogenophilales K WYL domain - - - - - - - - - - - - WYL k141_4907_1 1288826.MSNKSG1_08893 0.0 972.0 2FJNS@1|root,34BBY@2|Bacteria,1NZSG@1224|Proteobacteria,1ST2V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4907_2 1288826.MSNKSG1_08898 1.24e-205 570.0 COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,466Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S FlgJ-related protein bax - - ko:K03796 - - - - ko00000 - GH73 - Glucosaminidase k141_4907_3 1288826.MSNKSG1_08903 1.17e-218 603.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,464NS@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase yihG - - - - - - - - - - - Acyltransferase k141_4907_4 1288826.MSNKSG1_08908 0.0 964.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1S2DV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_18159_1 1095769.CAHF01000022_gene432 1.05e-130 416.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_12590_2 1125863.JAFN01000001_gene485 2.54e-29 117.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Major facilitator superfamily - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_14684_1 1278309.KB907105_gene1428 4.74e-266 730.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XHJA@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N k141_14684_2 1278309.KB907105_gene1429 5.72e-73 223.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1XKDJ@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - ACP_PD k141_20959_1 756272.Plabr_0677 1.32e-70 224.0 COG1509@1|root,COG1509@2|Bacteria,2IYGS@203682|Planctomycetes 203682|Planctomycetes C lysine 2,3-aminomutase - - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Radical_SAM k141_5613_1 1168067.JAGP01000001_gene402 8.18e-11 62.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,45ZP3@72273|Thiotrichales 72273|Thiotrichales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_5613_2 1123518.ARWI01000001_gene1886 3.54e-54 174.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM DJ-1 family protein thiJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_12610_1 225937.HP15_3786 3.41e-110 328.0 COG2807@1|root,COG2807@2|Bacteria 2|Bacteria P transmembrane transport - - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 k141_12610_2 1288826.MSNKSG1_15057 1.22e-95 278.0 COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,1S41A@1236|Gammaproteobacteria,4674S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant ectC - 4.2.1.108 ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06979 RC01729 ko00000,ko00001,ko00002,ko01000 - - - Ectoine_synth k141_12610_3 1288826.MSNKSG1_15062 0.0 920.0 COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,1T3BC@1236|Gammaproteobacteria,465YW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF3482) - - - - - - - - - - - - DUF3482,MMR_HSR1 k141_11236_1 1506583.JQJY01000001_gene327 2.6e-22 100.0 COG1404@1|root,COG1404@2|Bacteria,4NV7R@976|Bacteroidetes,1I5QQ@117743|Flavobacteriia,2NV28@237|Flavobacterium 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_19570_1 1288826.MSNKSG1_05631 1.16e-99 294.0 COG1946@1|root,COG1946@2|Bacteria,1QTZJ@1224|Proteobacteria 1224|Proteobacteria I Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_3 k141_19570_2 1288826.MSNKSG1_05626 5.32e-31 112.0 COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,1SG1X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - AAA_33,Zeta_toxin k141_13994_1 1120983.KB894570_gene1782 4.08e-15 74.7 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,1JN1R@119043|Rhodobiaceae 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC k141_16782_1 1127673.GLIP_0483 2.21e-112 349.0 COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - - - - - - - - - - AMP-binding,AMP-binding_C,FabA k141_16782_2 697282.Mettu_3301 4.02e-36 128.0 COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,1S9TC@1236|Gammaproteobacteria,1XFD5@135618|Methylococcales 135618|Methylococcales S Membrane - - - - - - - - - - - - - k141_2136_1 1163407.UU7_12948 2.92e-12 72.8 COG3179@1|root,COG3409@1|root,COG4870@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S0VJ@1236|Gammaproteobacteria,1X4WD@135614|Xanthomonadales 135614|Xanthomonadales O Papain family cysteine protease - - - - - - - - - - - - Peptidase_C1 k141_20279_1 1042876.PPS_0966 2.37e-18 81.3 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1YVEB@136845|Pseudomonas putida group 1236|Gammaproteobacteria D Maf-like protein yhdE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_21752_1 1392490.JHZX01000001_gene2019 4.8e-110 330.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,1I085@117743|Flavobacteriia 976|Bacteroidetes G PFAM Mannitol dehydrogenase C-terminal domain uxaB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.17,1.1.1.58 ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00631 R02555,R02703 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_10641_1 1269813.ATUL01000011_gene594 1.13e-36 135.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales 135613|Chromatiales C PFAM Radical SAM - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_10641_2 1278309.KB907103_gene1140 8.75e-205 568.0 COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,1XIF4@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs dusC - - ko:K05541 - - - - ko00000,ko01000,ko03016 - - - Dus k141_10641_3 416348.Hlac_2724 9.93e-07 54.3 COG1514@1|root,arCOG01736@2157|Archaea,2XZ2M@28890|Euryarchaeota,23UQZ@183963|Halobacteria 183963|Halobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_16894_1 1288826.MSNKSG1_09123 1.14e-129 374.0 COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,46449@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleoid-associated protein ndpA - - ko:K06899 - - - - ko00000,ko03036 - - - NA37 k141_18287_1 1266998.ATUJ01000008_gene470 1.74e-77 237.0 COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,2U07P@28211|Alphaproteobacteria,2PV4B@265|Paracoccus 28211|Alphaproteobacteria Q DSBA-like thioredoxin domain nahD - - - - - - - - - - - DSBA k141_18287_2 1288826.MSNKSG1_04671 9.55e-06 49.3 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,1RRGS@1236|Gammaproteobacteria,46CPZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_5774_1 314278.NB231_15473 4.79e-08 55.8 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1WVYW@135613|Chromatiales 135613|Chromatiales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_5774_2 1515746.HR45_10995 1.96e-09 60.1 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,2QA5J@267890|Shewanellaceae 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease hflK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_859_1 1278309.KB907103_gene987 4.29e-192 534.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1XI7V@135619|Oceanospirillales 135619|Oceanospirillales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP ppnK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_859_2 1278309.KB907103_gene986 1.86e-155 444.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1XJ6V@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine - - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP k141_859_4 1278309.KB907103_gene984 1.57e-163 463.0 COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RWQU@1236|Gammaproteobacteria,1XN92@135619|Oceanospirillales 135619|Oceanospirillales T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS k141_859_5 1278309.KB907099_gene3150 2.28e-25 99.8 28Q4G@1|root,2ZCMR@2|Bacteria,1RAB3@1224|Proteobacteria,1S2N3@1236|Gammaproteobacteria,1XKF4@135619|Oceanospirillales 135619|Oceanospirillales S Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function syd - - ko:K15723 - - - - ko00000 - - - Syd k141_21136_1 522306.CAP2UW1_3815 1.24e-20 93.6 COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,1KQZ0@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria N Flagellar basal body rod FlgEFG protein C-terminal flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_21136_2 1122194.AUHU01000005_gene1031 5.5e-07 52.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,466VA@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar rod assembly protein muramidase FlgJ flgJ GO:0003674,GO:0005198 - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k141_9195_1 1170562.Cal6303_2824 1.18e-137 421.0 COG0474@1|root,COG0474@2|Bacteria,1G2C4@1117|Cyanobacteria,1HR73@1161|Nostocales 1117|Cyanobacteria P Cation transporting ATPase, C-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_1563_1 90814.KL370891_gene70 3.92e-59 204.0 COG0243@1|root,COG0243@2|Bacteria,1MX0A@1224|Proteobacteria,1S02G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Molydopterin dinucleotide binding domain - - 1.20.2.1,1.20.9.1 ko:K08356 - - - - ko00000,ko01000,ko02000 5.A.3.6 - - Molybdopterin,Molydop_binding k141_1563_2 859657.RPSI07_mp0919 2.32e-61 194.0 COG0723@1|root,COG0723@2|Bacteria,1RF8Q@1224|Proteobacteria,2VR6G@28216|Betaproteobacteria,1KDRT@119060|Burkholderiaceae 28216|Betaproteobacteria C arsenite oxidase, small subunit aoxA - 1.20.2.1,1.20.9.1 ko:K08355 - - - - ko00000,ko01000,ko02000 5.A.3.6 - - Rieske,TAT_signal k141_5021_1 1296415.JACC01000020_gene3775 1.61e-09 64.7 COG1858@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,COG5276@2|Bacteria,4NIPP@976|Bacteroidetes,1I7A8@117743|Flavobacteriia,2YKAC@290174|Aquimarina 976|Bacteroidetes MP Cellulose binding domain - - - - - - - - - - - - Big_5,CBM_3,Cytochrom_C,Cytochrom_D1,PKD k141_12715_1 187272.Mlg_1899 2.26e-45 159.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1WWEM@135613|Chromatiales 135613|Chromatiales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_12715_2 751994.AGIG01000028_gene1631 1.51e-08 57.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_10642_1 56780.SYN_00833 6.89e-79 252.0 COG1305@1|root,COG1305@2|Bacteria,1Q1D3@1224|Proteobacteria,43772@68525|delta/epsilon subdivisions,2WSIA@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Transglutaminase/protease-like homologues - - - - - - - - - - - - Transglut_core k141_18998_1 317025.Tcr_1556 8.46e-09 58.2 COG1226@1|root,COG1226@2|Bacteria,1R97G@1224|Proteobacteria,1RQAR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P PFAM Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 k141_18998_2 713586.KB900536_gene2600 1.09e-44 150.0 COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales 135613|Chromatiales Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_25 k141_7848_1 1288826.MSNKSG1_11638 1.22e-66 213.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,464FK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livM GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - iPC815.YPO3806,iSDY_1059.SDY_3605 BPD_transp_2,DUF3382 k141_7848_2 1288826.MSNKSG1_11643 9.01e-175 488.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,465SA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component livG GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - iECNA114_1301.ECNA114_3561 ABC_tran,BCA_ABC_TP_C k141_7848_3 1288826.MSNKSG1_11648 1.61e-159 447.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria,46A4K@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0410 ABC-type branched-chain amino acid transport systems, ATPase component livF GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - iAPECO1_1312.APECO1_3005,iECs_1301.ECs4301,iSSON_1240.SSON_3692,iUTI89_1310.UTI89_C3961,iYL1228.KPN_03816,iZ_1308.Z4824 ABC_tran,BCA_ABC_TP_C k141_7848_4 1288826.MSNKSG1_11653 8.72e-98 285.0 2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3015) - - - - - - - - - - - - DUF3015 k141_7848_5 1288826.MSNKSG1_11658 3.95e-245 684.0 28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,1RRQ0@1236|Gammaproteobacteria,464R0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 k141_13425_1 998088.B565_2251 7.17e-106 315.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1Y3SJ@135624|Aeromonadales 135624|Aeromonadales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_146_1 1288826.MSNKSG1_07983 1.51e-181 508.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,467GB@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin znuA GO:0000041,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008270,GO:0030001,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - iECs_1301.ECs2567,iEcSMS35_1347.EcSMS35_1329,iPC815.YPO2061,iZ_1308.Z2909 ZnuA k141_146_2 1288826.MSNKSG1_07988 2.74e-49 165.0 COG0679@1|root,COG0679@2|Bacteria,1RA01@1224|Proteobacteria,1SZPD@1236|Gammaproteobacteria,467T3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_14827_1 264730.PSPPH_4331 1.17e-27 105.0 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,1Z9YY@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - - - - - - - - - - PilZ k141_14827_2 1049564.TevJSym_ac00810 3.61e-51 175.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1J4T3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorB yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_6433_1 335283.Neut_1291 2.31e-34 132.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria,374PN@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_6433_2 1288826.MSNKSG1_05958 8.27e-149 437.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,465JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_9891_1 1288826.MSNKSG1_13187 0.0 1807.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,465HN@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547 Aconitase,Aconitase_C k141_20419_2 870187.Thini_0149 9.14e-25 98.2 COG2932@1|root,COG2932@2|Bacteria,1NBZE@1224|Proteobacteria,1S6MQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Peptidase S24-like - - - - - - - - - - - - Peptidase_S24 k141_20419_3 713587.THITH_08655 4.57e-69 213.0 COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1WY49@135613|Chromatiales 135613|Chromatiales P PFAM Rhodanese-like - - - - - - - - - - - - Rhodanese k141_16915_1 472759.Nhal_0920 1.47e-37 148.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales 135613|Chromatiales M PFAM AsmA family protein - - - ko:K07289 - - - - ko00000 - - - AsmA k141_15560_1 1288826.MSNKSG1_10443 4.45e-233 644.0 COG2199@1|root,COG3706@2|Bacteria,1R9Z4@1224|Proteobacteria,1RNSX@1236|Gammaproteobacteria,469QP@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_15560_2 1288826.MSNKSG1_10448 1.12e-09 57.8 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,46AMD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - 3.1.4.54 ko:K13985 ko04723,map04723 - - - ko00000,ko00001,ko01000 - - - Lactamase_B_2 k141_21774_1 1049564.TevJSym_ar00370 5.11e-62 204.0 COG1142@1|root,COG1142@2|Bacteria,1RIXA@1224|Proteobacteria,1SBMD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - - k141_18306_1 28229.ND2E_3272 3.58e-52 175.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,2Q7U6@267889|Colwelliaceae 1236|Gammaproteobacteria NT Methyltransferase, chemotaxis proteins cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_18306_2 1117315.AHCA01000027_gene4167 1.42e-29 111.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,2Q2NT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_18306_3 998088.B565_2605 7.27e-27 102.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,1Y4CY@135624|Aeromonadales 135624|Aeromonadales N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_2985_1 870187.Thini_3777 8.31e-24 99.4 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria 1224|Proteobacteria C PFAM Polysulphide reductase, NrfD dsrP - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_2985_2 648757.Rvan_0590 1.23e-27 107.0 COG0437@1|root,COG0437@2|Bacteria,1QUMM@1224|Proteobacteria 1224|Proteobacteria C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - ko:K00184,ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3,5.A.3.10 - - Fer4_11,Fer4_3,Fer4_4,Fer4_6,Fer4_7 k141_12741_1 1237149.C900_00894 2.82e-74 243.0 COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA,PD40,TPR_16,TPR_2,TPR_8 k141_5802_1 1278309.KB907100_gene2297 3.73e-129 378.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales 135619|Oceanospirillales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_8559_1 75379.Tint_3214 9.32e-05 48.1 COG0597@1|root,COG0671@1|root,COG0597@2|Bacteria,COG0671@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,1KKU6@119065|unclassified Burkholderiales 28216|Betaproteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_8559_2 1121403.AUCV01000015_gene4712 3.41e-25 105.0 COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,42WVD@68525|delta/epsilon subdivisions 1224|Proteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_12038_1 1415754.JQMK01000013_gene122 1.41e-16 80.5 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,46AFY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Mo-co oxidoreductase dimerisation domain - - - ko:K17225 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Mo-co_dimer,Oxidored_molyb k141_16206_1 1278309.KB907099_gene2467 5.56e-160 472.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XI1I@135619|Oceanospirillales 135619|Oceanospirillales L Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C - - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_16206_2 1278309.KB907099_gene2466 7.67e-199 556.0 COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria,1XJ0Z@135619|Oceanospirillales 135619|Oceanospirillales I GHMP kinases N terminal domain - - - - - - - - - - - - GHMP_kinases_N k141_16206_3 207954.MED92_02384 4.67e-66 211.0 COG1577@1|root,COG1577@2|Bacteria,1NF04@1224|Proteobacteria,1RPXQ@1236|Gammaproteobacteria,1XIA1@135619|Oceanospirillales 135619|Oceanospirillales I GHMP kinases C terminal - - - - - - - - - - - - GHMP_kinases_C,GHMP_kinases_N k141_163_1 998674.ATTE01000001_gene650 2.38e-21 86.3 COG4321@1|root,COG4321@2|Bacteria,1MZP2@1224|Proteobacteria,1S865@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - - - - - - - - - - RHH_4 k141_163_2 207954.MED92_05268 4.69e-114 329.0 COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,1RPRR@1236|Gammaproteobacteria,1XIIZ@135619|Oceanospirillales 135619|Oceanospirillales S Intracellular protease - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_5039_1 1056820.KB900652_gene3325 2.53e-49 167.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,2PQ0Q@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D ATPase MipZ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_5803_1 1094980.Mpsy_2220 4.29e-10 65.5 COG0642@1|root,arCOG02350@1|root,arCOG06712@1|root,arCOG02350@2157|Archaea,arCOG06712@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota 28890|Euryarchaeota T Signal transduction histidine kinase - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_9,sCache_3_3 k141_14849_1 547042.BACCOPRO_00394 1.4e-08 59.3 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia,4AQ4F@815|Bacteroidaceae 976|Bacteroidetes CO Thioredoxin - - - - - - - - - - - - AhpC-TSA,DUF4369,Thioredoxin_8 k141_14849_2 935948.KE386494_gene83 3.68e-22 99.4 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,42ENF@68295|Thermoanaerobacterales 186801|Clostridia T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_12742_1 314232.SKA53_02336 4.73e-110 326.0 COG3239@1|root,COG3239@2|Bacteria,1R42Z@1224|Proteobacteria,2TU07@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_21776_1 395494.Galf_2203 1.55e-40 149.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,44VA4@713636|Nitrosomonadales 28216|Betaproteobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_4376_1 1232683.ADIMK_4139 7.97e-148 452.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,464EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Putative amidoligase enzyme (DUF2126) IV02_11925 - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core k141_20420_1 1395513.P343_11360 4.15e-53 191.0 COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,4HCJG@91061|Bacilli 91061|Bacilli O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_14850_1 1179773.BN6_45930 4.46e-05 50.8 COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria,4E2CE@85010|Pseudonocardiales 201174|Actinobacteria C Elongator protein 3, MiaB family, Radical SAM - - - ko:K18537,ko:K21224 ko01059,ko01130,map01059,map01130 M00831 R11389 RC03430 ko00000,ko00001,ko00002 - - - B12-binding,Radical_SAM k141_164_1 590998.Celf_1265 3.52e-13 67.0 COG2146@1|root,COG2146@2|Bacteria,2IQM4@201174|Actinobacteria,4F1H1@85016|Cellulomonadaceae 201174|Actinobacteria P TIGRFAM nitrite reductase NAD(P)H , small subunit nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske_2 k141_164_2 1286106.MPL1_12191 2.14e-48 160.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales 72273|Thiotrichales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_2987_1 290512.Paes_2153 1.07e-36 130.0 COG0518@1|root,COG0518@2|Bacteria,1FE7U@1090|Chlorobi 1090|Chlorobi F PFAM glutamine amidotransferase class-I - - - - - - - - - - - - GATase k141_2987_2 1123514.KB905899_gene846 1.76e-27 106.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_5040_2 765912.Thimo_1463 3.16e-72 239.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales 135613|Chromatiales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_12743_1 1278309.KB907105_gene1482 3.96e-107 322.0 COG0348@1|root,COG0348@2|Bacteria,1MWZ4@1224|Proteobacteria,1RQZX@1236|Gammaproteobacteria,1XINI@135619|Oceanospirillales 135619|Oceanospirillales C IG-like fold at C-terminal of FixG, putative oxidoreductase - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_20421_2 1123368.AUIS01000009_gene2513 9.64e-28 114.0 COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - GAF,GAF_3,HDOD,Pkinase k141_1578_1 1288826.MSNKSG1_12402 3.04e-58 194.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,469WI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_1578_2 1288826.MSNKSG1_12397 0.0 951.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - CHASE,EAL,GGDEF,PAS,PAS_4,PAS_9 k141_1578_3 1288826.MSNKSG1_12392 1.88e-175 493.0 COG4977@1|root,COG4977@2|Bacteria,1NDWA@1224|Proteobacteria,1SYZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 k141_1578_4 1288826.MSNKSG1_12387 6.38e-18 82.4 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_17615_1 56110.Oscil6304_3489 1.16e-38 151.0 COG0515@1|root,COG0642@1|root,COG3899@1|root,COG4251@1|root,COG5002@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - - - - - - - - - - AAA_16,GAF,GGDEF,Guanylate_cyc,HATPase_c,HisKA,HisKA_3,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE k141_8560_1 1380358.JADJ01000007_gene2911 1.05e-19 86.7 28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,1RMAM@1236|Gammaproteobacteria,1XN26@135619|Oceanospirillales 135619|Oceanospirillales S RES domain - - - - - - - - - - - - RES k141_8560_2 305900.GV64_22260 6.13e-98 294.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_19022_1 1499967.BAYZ01000076_gene804 1.84e-24 99.0 COG3417@1|root,COG3417@2|Bacteria,2NQZZ@2323|unclassified Bacteria 2|Bacteria M Peptidoglycan-synthase activator LpoB lpoB GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07337,ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - LpoB k141_19022_2 1202962.KB907170_gene2408 9.12e-21 89.4 2EUFJ@1|root,33MXU@2|Bacteria,1NZHB@1224|Proteobacteria,1SQC7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LPP20 lipoprotein - - - - - - - - - - - - LPP20 k141_7866_1 1122201.AUAZ01000023_gene2987 7.62e-112 329.0 COG3703@1|root,COG3703@2|Bacteria,1PJ04@1224|Proteobacteria,1S2RZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P AIG2-like family - - - - - - - - - - - - AIG2_2 k141_7866_2 1122201.AUAZ01000023_gene2988 7.43e-66 206.0 28Q1W@1|root,2ZCK4@2|Bacteria,1RDIF@1224|Proteobacteria,1S4Y2@1236|Gammaproteobacteria,467SB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12744_1 491205.JARQ01000004_gene2382 4.89e-50 182.0 COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia,3ZNM7@59732|Chryseobacterium 976|Bacteroidetes M RHS repeat-associated core domain protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_19023_1 1049564.TevJSym_bi00190 1.49e-72 236.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_5041_1 580332.Slit_1617 2.03e-134 397.0 COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the NiFe NiFeSe hydrogenase large subunit family - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases k141_20423_1 243233.MCA1302 9.84e-85 260.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XEPK@135618|Methylococcales 135618|Methylococcales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_4377_1 396588.Tgr7_3073 4.56e-67 215.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales 135613|Chromatiales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_4377_2 251229.Chro_4000 2.63e-82 253.0 COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales 1117|Cyanobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_3159_1 1278309.KB907100_gene2291 2.33e-42 154.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XHRC@135619|Oceanospirillales 135619|Oceanospirillales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_3159_2 156578.ATW7_16303 5.59e-30 116.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_8695_1 1278309.KB907106_gene1330 1.82e-07 50.4 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1XHWV@135619|Oceanospirillales 135619|Oceanospirillales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_8695_2 1122197.ATWI01000013_gene2359 2.31e-25 95.1 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,468BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L30 rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_8695_3 1278309.KB907106_gene1332 6.79e-88 259.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XJJ2@135619|Oceanospirillales 135619|Oceanospirillales J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_8695_4 1278309.KB907106_gene1333 6.21e-301 823.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1XHSE@135619|Oceanospirillales 135619|Oceanospirillales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_8695_5 1278309.KB907106_gene1335 6.64e-45 147.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1XJXT@135619|Oceanospirillales 135619|Oceanospirillales J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_7314_1 194699.Q775D4_BPBPP 8.15e-33 130.0 4QHMX@10239|Viruses,4QW8C@35237|dsDNA viruses no RNA stage,4QRQS@28883|Caudovirales,4QNWI@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k141_12200_1 1049564.TevJSym_ag00360 2.5e-73 228.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1J52V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases crp GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,cNMP_binding k141_19827_1 1288826.MSNKSG1_14042 2.31e-180 504.0 COG4977@1|root,COG4977@2|Bacteria,1MXZQ@1224|Proteobacteria,1RQM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator tetD - - ko:K07506 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18,HTH_AraC k141_19827_2 1288826.MSNKSG1_14037 8.06e-30 112.0 COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,1RNSM@1236|Gammaproteobacteria,466Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily pagO - - - - - - - - - - - EamA k141_14970_1 398767.Glov_2300 1.76e-34 134.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria 28221|Deltaproteobacteria U SMART AAA ATPase exeA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 k141_14252_1 566466.NOR53_546 1.69e-54 174.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1JB6E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL k141_14252_3 935840.JAEQ01000001_gene2685 5.55e-10 59.3 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,43H25@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_9350_2 1288826.MSNKSG1_08583 1.3e-138 394.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,465UP@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 k141_5917_1 247633.GP2143_07634 2.67e-12 67.4 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1J4V3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_5917_2 1209072.ALBT01000012_gene3379 7.47e-24 101.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1FGH9@10|Cellvibrio 1236|Gammaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_346_1 234267.Acid_7866 1.38e-37 137.0 COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria 57723|Acidobacteria K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg k141_346_2 1517416.IDAT_01290 1.88e-42 154.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,2QF1P@267893|Idiomarinaceae 1236|Gammaproteobacteria J The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_15673_1 1288826.MSNKSG1_08593 1.22e-47 163.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,1RPSF@1236|Gammaproteobacteria,46D4F@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0477 Permeases of the major facilitator superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 k141_15673_2 1288826.MSNKSG1_08588 1.68e-64 197.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,468DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L methylated DNA-protein cysteine methyltransferase ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_12201_1 998674.ATTE01000001_gene2142 3.27e-108 330.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales 72273|Thiotrichales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_11502_1 292415.Tbd_1939 4.36e-16 74.7 2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria,2W3YC@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_11502_3 395493.BegalDRAFT_1886 1.19e-40 139.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,460DI@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 k141_8696_1 713586.KB900536_gene635 1.23e-58 203.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1WXN2@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) - - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_19200_1 396588.Tgr7_2396 5.67e-43 157.0 COG1716@1|root,COG3267@1|root,COG1716@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WWX7@135613|Chromatiales 135613|Chromatiales U Type II secretory pathway component ExeA - - - ko:K02450,ko:K12283 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 k141_7315_1 1537994.JQFW01000015_gene1788 3.19e-12 64.3 COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,468DU@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_7315_2 686578.AFFX01000001_gene1045 2.45e-26 109.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_10067_1 1288826.MSNKSG1_12097 9.9e-62 194.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,464CI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_10067_2 1288826.MSNKSG1_12102 1.14e-202 563.0 COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,4643P@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yedI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K09781 - - - - ko00000 - - - DUF808 k141_10067_3 1122197.ATWI01000011_gene365 4.91e-29 113.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_19828_1 935863.AWZR01000012_gene2490 1.56e-58 186.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1X3UG@135614|Xanthomonadales 135614|Xanthomonadales A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_19828_2 998088.B565_2087 8.42e-30 116.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1Y3UR@135624|Aeromonadales 135624|Aeromonadales L Exonuclease C-terminal - - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_14971_1 640511.BC1002_6176 8.25e-72 230.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,2VIN0@28216|Betaproteobacteria,1K58E@119060|Burkholderiaceae 28216|Betaproteobacteria Q benzoate transporter benE - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_15674_2 757424.Hsero_2247 1.68e-20 91.7 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,473UV@75682|Oxalobacteraceae 28216|Betaproteobacteria S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_15674_3 617140.AJZE01000079_gene1792 3.01e-11 60.8 2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,1SCY3@1236|Gammaproteobacteria,1XYVA@135623|Vibrionales 135623|Vibrionales S Family of unknown function (DUF5329) - - - - - - - - - - - - DUF5329 k141_21966_1 2340.JV46_08070 1.46e-126 374.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1J54W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim k141_21966_2 2340.JV46_08040 2.23e-142 405.0 COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1J5WI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0678 Peroxiredoxin VY92_02980 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Glutaredoxin,Redoxin k141_21966_3 1385517.N800_07205 1.38e-24 94.0 COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1X84M@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2061) - - - - - - - - - - - - DUF2061 k141_19829_1 1116375.VEJY3_13355 3.44e-107 318.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1XSKJ@135623|Vibrionales 135623|Vibrionales C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_10068_1 870187.Thini_1499 1.19e-83 256.0 COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,46091@72273|Thiotrichales 72273|Thiotrichales S PFAM Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_347_1 95619.PM1_0218070 1.25e-47 172.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS k141_2423_1 1122599.AUGR01000010_gene1057 1.04e-150 430.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria,1XH6G@135619|Oceanospirillales 135619|Oceanospirillales E Glycine betaine - - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_2423_2 1122599.AUGR01000010_gene1056 0.0 988.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XHHA@135619|Oceanospirillales 135619|Oceanospirillales E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate betA - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_2423_3 1122599.AUGR01000010_gene1055 3.25e-168 481.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIMQ@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14972_1 1288826.MSNKSG1_04816 4.42e-151 437.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_16324_1 1278309.KB907099_gene3031 5.01e-41 139.0 COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,1XK46@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_16324_2 1278309.KB907099_gene3032 3.61e-303 830.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XIXB@135619|Oceanospirillales 135619|Oceanospirillales T With GlrK is part of a two-component signal transduction system regulating glmY - - - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_16324_3 1278309.KB907099_gene3033 4.67e-69 213.0 28YD3@1|root,2ZK7N@2|Bacteria,1PBP9@1224|Proteobacteria,1SVT7@1236|Gammaproteobacteria,1XQHJ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16324_4 1278309.KB907099_gene3034 9.04e-275 758.0 COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,1XJ2K@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_16324_6 1278309.KB907099_gene3036 2.97e-160 453.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1XHXA@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase k141_16324_7 1278309.KB907099_gene3037 2.12e-126 379.0 2DPKZ@1|root,332KF@2|Bacteria,1ND7M@1224|Proteobacteria,1SG2I@1236|Gammaproteobacteria,1XMUH@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16324_8 207954.MED92_14508 4.17e-30 113.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,1S3X9@1236|Gammaproteobacteria,1XJU6@135619|Oceanospirillales 135619|Oceanospirillales O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k141_1763_1 1056820.KB900674_gene2513 1.08e-49 181.0 COG1729@1|root,COG1729@2|Bacteria,1R6YY@1224|Proteobacteria,1S0WM@1236|Gammaproteobacteria,2PQ80@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_5185_1 1288826.MSNKSG1_04586 4.91e-156 446.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,4660W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent protease, contains TPR repeats - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_2,TPR_8 k141_5185_2 1288826.MSNKSG1_04581 4.45e-120 343.0 2B831@1|root,321AX@2|Bacteria,1RIGM@1224|Proteobacteria,1S7NV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5185_3 1288826.MSNKSG1_04576 1.18e-181 511.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,46DFU@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1454 Alcohol dehydrogenase, class IV - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_6567_3 1244869.H261_04510 3.08e-14 74.7 COG0834@1|root,COG0834@2|Bacteria,1N0VS@1224|Proteobacteria,2U2J2@28211|Alphaproteobacteria 28211|Alphaproteobacteria ET Bacterial extracellular solute-binding proteins, family 3 - - - - - - - - - - - - SBP_bac_3 k141_7316_2 935836.JAEL01000015_gene243 5.54e-57 180.0 COG0599@1|root,COG0599@2|Bacteria,1V78I@1239|Firmicutes,4HH8J@91061|Bacilli,1ZG1T@1386|Bacillus 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_7316_3 207954.MED92_06118 2.36e-06 49.3 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1RS3Z@1236|Gammaproteobacteria,1XKTC@135619|Oceanospirillales 135619|Oceanospirillales S Sodium Bile acid symporter family - - - - - - - - - - - - Mem_trans k141_14973_1 398580.Dshi_2080 1.57e-84 257.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E reductase metF GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_5186_1 1123517.JOMR01000001_gene1909 9.2e-09 61.6 COG3203@1|root,COG3203@2|Bacteria,1RKZ1@1224|Proteobacteria,1SWVR@1236|Gammaproteobacteria,4627Z@72273|Thiotrichales 72273|Thiotrichales M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_5918_1 1123257.AUFV01000017_gene3775 5.2e-07 50.8 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RRA7@1236|Gammaproteobacteria,1X4AW@135614|Xanthomonadales 135614|Xanthomonadales S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k141_5918_2 1415780.JPOG01000001_gene2466 1.37e-93 282.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,1X366@135614|Xanthomonadales 135614|Xanthomonadales O Proteasome subunit - - - ko:K07395 - - - - ko00000 - - - Proteasome k141_9351_1 1335757.SPICUR_03510 7.85e-115 345.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1WVVK@135613|Chromatiales 135613|Chromatiales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_8072_2 1288826.MSNKSG1_04666 1.1e-125 358.0 COG3470@1|root,COG3470@2|Bacteria,1RA2Z@1224|Proteobacteria,1RS32@1236|Gammaproteobacteria 1236|Gammaproteobacteria P protein probably involved in high-affinity Fe2 transport tpd - - ko:K07230 - - - - ko00000,ko02000 2.A.108.2.10,2.A.108.2.4,2.A.108.2.9 - - Iron_transport k141_8072_3 1288826.MSNKSG1_04671 1.48e-246 677.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,1RRGS@1236|Gammaproteobacteria,46CPZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_8072_4 1288826.MSNKSG1_04676 3.46e-249 697.0 COG4716@1|root,COG4716@2|Bacteria,1MVTV@1224|Proteobacteria,1RQMG@1236|Gammaproteobacteria,469F5@72275|Alteromonadaceae 1236|Gammaproteobacteria S MCRA family mycA - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA k141_10069_1 1288826.MSNKSG1_16601 7.05e-75 232.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,1RPSG@1236|Gammaproteobacteria,464E6@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yeiH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cons_hypoth698 k141_10069_2 1288826.MSNKSG1_16596 2.23e-143 423.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,465EX@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_14253_2 1318617.MGM1_2020 6.74e-09 61.2 COG0558@1|root,COG0558@2|Bacteria,3WTR9@544448|Tenericutes 544448|Tenericutes I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_6568_1 713586.KB900536_gene2820 9.81e-21 90.1 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 k141_6568_2 1469245.JFBG01000023_gene1275 3.04e-68 220.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales 135613|Chromatiales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_3816_1 1278309.KB907101_gene674 2.11e-53 172.0 2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,1S4JB@1236|Gammaproteobacteria,1XJQ4@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2889) - - - - - - - - - - - - DUF2889 k141_3816_2 1042375.AFPL01000036_gene3004 3.59e-84 256.0 COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,1RR7B@1236|Gammaproteobacteria 1236|Gammaproteobacteria K phenylacetic acid degradation operon negative regulatory protein paaX GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C k141_12203_1 1278309.KB907099_gene2507 1.28e-176 495.0 COG3384@1|root,COG3384@2|Bacteria,1NRQK@1224|Proteobacteria,1SMJ3@1236|Gammaproteobacteria,1XP1W@135619|Oceanospirillales 135619|Oceanospirillales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_12203_2 207954.MED92_10469 5.86e-93 282.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1XHN5@135619|Oceanospirillales 135619|Oceanospirillales S Iron-sulfur cluster-binding domain pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_2425_1 1461693.ATO10_07632 9.06e-56 187.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M k141_14976_4 1288826.MSNKSG1_07728 4.7e-148 417.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,46400@72275|Alteromonadaceae 1236|Gammaproteobacteria OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_14976_5 1288826.MSNKSG1_07723 1.65e-302 825.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,464XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_14976_6 1288826.MSNKSG1_07718 0.0 1536.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,464ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_14976_7 1288826.MSNKSG1_07713 1.56e-51 164.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,467ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_14976_8 1288826.MSNKSG1_07708 0.0 1099.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,4643B@72275|Alteromonadaceae 1236|Gammaproteobacteria O peptidylprolyl isomerase ppiD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_14976_9 1288826.MSNKSG1_07703 2.32e-201 558.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,465QI@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1737 Transcriptional regulators hexR GO:0000976,GO:0001067,GO:0001130,GO:0001131,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_14976_10 1288826.MSNKSG1_07698 0.0 976.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,464A8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf GO:0003674,GO:0003824,GO:0004345,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0009117,GO:0009372,GO:0009987,GO:0010699,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0023052,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - e_coli_core.b1852,iAF1260.b1852,iBWG_1329.BWG_1666,iE2348C_1286.E2348C_1977,iEC042_1314.EC042_2019,iECABU_c1320.ECABU_c21130,iECDH10B_1368.ECDH10B_1993,iECDH1ME8569_1439.ECDH1ME8569_1798,iECED1_1282.ECED1_2057,iECIAI39_1322.ECIAI39_1198,iECNA114_1301.ECNA114_1899,iECO26_1355.ECO26_2690,iECP_1309.ECP_1796,iECSF_1327.ECSF_1710,iECUMN_1333.ECUMN_2149,iECW_1372.ECW_m2026,iEKO11_1354.EKO11_1918,iEcDH1_1363.EcDH1_1789,iEcE24377_1341.EcE24377A_2082,iEcHS_1320.EcHS_A1944,iEcSMS35_1347.EcSMS35_1335,iEcolC_1368.EcolC_1780,iG2583_1286.G2583_2304,iJO1366.b1852,iJR904.b1852,iLF82_1304.LF82_3733,iNRG857_1313.NRG857_09280,iSDY_1059.SDY_1138,iWFL_1372.ECW_m2026,iY75_1357.Y75_RS09725,iYL1228.KPN_02367,ic_1306.c2265 G6PD_C,G6PD_N k141_14976_11 1288826.MSNKSG1_07693 1.83e-148 420.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1S4TG@1236|Gammaproteobacteria,46DJ2@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_14976_12 1288826.MSNKSG1_07688 1.12e-120 346.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,465M9@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase eda GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - iECOK1_1307.ECOK1_1968,iYL1228.KPN_02365 Aldolase k141_19343_1 351348.Maqu_1978 9.37e-74 242.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,465FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_14370_1 1255043.TVNIR_3017 1.35e-32 126.0 COG2391@1|root,COG2391@2|Bacteria,1MWWP@1224|Proteobacteria,1RR58@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Inner membrane protein PRK11099 yeeE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_4713_1 292415.Tbd_1366 1.11e-80 264.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2W14J@28216|Betaproteobacteria 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4 k141_12392_1 1415754.JQMK01000002_gene3345 4.24e-19 87.8 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_21437_1 1278309.KB907100_gene2153 2.8e-124 362.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XHHT@135619|Oceanospirillales 135619|Oceanospirillales D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_16515_1 1137799.GZ78_12945 1.79e-131 403.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_17955_1 1117647.M5M_18955 3.15e-81 270.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J7SU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9 k141_7480_1 351348.Maqu_0652 1.26e-107 320.0 COG4643@1|root,COG4643@2|Bacteria,1MVGY@1224|Proteobacteria,1S7S5@1236|Gammaproteobacteria,46AWU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Toprim domain - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Toprim_3,Toprim_4 k141_8214_1 767434.Fraau_2389 9.12e-74 244.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1X3CX@135614|Xanthomonadales 135614|Xanthomonadales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_13761_1 519989.ECTPHS_01969 1.18e-155 452.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_19344_1 1278309.KB907102_gene33 5.14e-69 212.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XJ5T@135619|Oceanospirillales 135619|Oceanospirillales H May be involved in the biosynthesis of molybdopterin - - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_6028_1 1123393.KB891326_gene13 9.4e-62 194.0 COG1416@1|root,COG1416@2|Bacteria,1NAV2@1224|Proteobacteria 1224|Proteobacteria - - - - - ko:K09004 - - - - ko00000 - - - DrsE k141_6028_2 1123514.KB905899_gene1933 7.73e-30 116.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_17212_2 404380.Gbem_3172 7.38e-29 111.0 COG4968@1|root,COG4968@2|Bacteria,1N31J@1224|Proteobacteria 1224|Proteobacteria U Prokaryotic N-terminal methylation motif - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl k141_17956_1 1089439.KB902267_gene5 4.81e-31 110.0 arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_14371_1 1439940.BAY1663_01811 7.54e-62 215.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_3946_1 713586.KB900536_gene2509 6.74e-79 248.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WWMQ@135613|Chromatiales 135613|Chromatiales C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_21438_1 1268068.PG5_15670 5.03e-24 94.7 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria 1236|Gammaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_21438_2 983545.Glaag_2635 1.68e-93 297.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_1224_1 582744.Msip34_1301 3.81e-84 261.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,2KKWV@206350|Nitrosomonadales 206350|Nitrosomonadales S Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_1224_2 1286106.MPL1_07443 1.52e-17 78.2 COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer Membrane Lipoprotein blc4 - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_513_1 666509.RCA23_c11990 2.11e-59 188.0 COG0410@1|root,COG0410@2|Bacteria,1R8FA@1224|Proteobacteria,2U0JB@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_513_2 1192034.CAP_6416 7e-07 53.1 COG1073@1|root,COG1073@2|Bacteria,1NX86@1224|Proteobacteria,42QXW@68525|delta/epsilon subdivisions,2WN43@28221|Deltaproteobacteria,2YZ5P@29|Myxococcales 28221|Deltaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_4715_1 40215.BBOS01000086_gene3228 3.09e-69 227.0 arCOG06613@1|root,2Z7VT@2|Bacteria,1MVIU@1224|Proteobacteria,1RZ5H@1236|Gammaproteobacteria,3NRC2@468|Moraxellaceae 1236|Gammaproteobacteria S AIPR protein - - - - - - - - - - - - AIPR k141_8801_1 1121271.AUCM01000005_gene666 2.84e-120 352.0 COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria 28211|Alphaproteobacteria D COG1192 ATPases involved in chromosome partitioning mipZ - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - MipZ k141_15102_1 1278309.KB907103_gene1199 2.14e-17 78.6 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XJWG@135619|Oceanospirillales 135619|Oceanospirillales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 k141_15102_2 1278309.KB907103_gene1195 7.78e-317 870.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1XHDV@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_15102_3 674977.VMC_40630 2.94e-50 162.0 COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1XY2Z@135623|Vibrionales 135623|Vibrionales S Glyoxalase-like domain - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_10969_2 1288826.MSNKSG1_02464 0.0 921.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,465KT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_10969_3 1288826.MSNKSG1_02469 8.95e-148 417.0 COG4566@1|root,COG4566@2|Bacteria,1R496@1224|Proteobacteria,1SKGC@1236|Gammaproteobacteria,46CHQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_10969_4 1288826.MSNKSG1_02474 0.0 900.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RZ3B@1236|Gammaproteobacteria,46CH7@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2202 FOG PAS PAC domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9 k141_10969_5 1288826.MSNKSG1_02479 4.16e-79 249.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,465TS@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_533_2 1288826.MSNKSG1_13822 3.06e-108 318.0 COG0697@1|root,COG0697@2|Bacteria,1R9B0@1224|Proteobacteria,1RZ6Q@1236|Gammaproteobacteria,466YI@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA k141_11660_1 522306.CAP2UW1_0384 6.41e-94 300.0 COG2885@1|root,COG3808@1|root,COG2885@2|Bacteria,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KQ7I@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA k141_13781_1 396588.Tgr7_2292 3.28e-144 418.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_2577_1 1298593.TOL_2835 1.46e-43 153.0 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S10P@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_2577_3 1123400.KB904747_gene398 1.89e-07 52.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,45ZRV@72273|Thiotrichales 72273|Thiotrichales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_7489_1 1278309.KB907105_gene1437 2.73e-119 350.0 COG0183@1|root,COG0183@2|Bacteria,1R6V1@1224|Proteobacteria,1S0V8@1236|Gammaproteobacteria,1XHFS@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - - - - - - - - - - - - k141_7489_2 1278309.KB907105_gene1439 5.96e-180 503.0 COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,1XIH8@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K00243 - - - - ko00000 - - - S1_2 k141_7489_3 1278309.KB907105_gene1440 2.41e-105 305.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,1XJD2@135619|Oceanospirillales 135619|Oceanospirillales H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS k141_7489_4 1278309.KB907105_gene1441 1.21e-138 397.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1S3KK@1236|Gammaproteobacteria,1XJT6@135619|Oceanospirillales 135619|Oceanospirillales E Spermidine synthase - - - - - - - - - - - - Spermine_synth k141_7489_6 1278309.KB907105_gene1443 2.72e-299 819.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,1XHP8@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_7489_7 1278309.KB907105_gene1444 2.8e-286 799.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,1XIPK@135619|Oceanospirillales 135619|Oceanospirillales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_7489_8 1278309.KB907105_gene1445 6.04e-248 681.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,1XIIR@135619|Oceanospirillales 135619|Oceanospirillales K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_18617_1 713586.KB900536_gene1606 1.52e-14 71.2 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales 135613|Chromatiales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_18617_2 754477.Q7C_1175 3.49e-29 117.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales 72273|Thiotrichales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_10257_1 95619.PM1_0226155 1.61e-60 199.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_10257_2 261292.Nit79A3_2779 1e-31 121.0 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,372D9@32003|Nitrosomonadales 28216|Betaproteobacteria I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_15870_1 1333998.M2A_2383 1.47e-53 183.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,4BR3W@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P NMT1-like family nrt - - ko:K02051,ko:K15576,ko:K22067 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko02000,ko02022 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17 - - NMT1_2 k141_15870_2 1122201.AUAZ01000039_gene3278 1.57e-102 310.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_13085_1 1278309.KB907101_gene635 1.2e-66 212.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1XIW9@135619|Oceanospirillales 135619|Oceanospirillales OU peptidase sohB - - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_13085_2 1278309.KB907101_gene636 1.23e-115 335.0 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,1XJJB@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - TetR_N k141_13085_3 1123517.JOMR01000001_gene986 1.35e-71 219.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,460TV@72273|Thiotrichales 72273|Thiotrichales S PFAM L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_13085_4 1278309.KB907101_gene638 3.67e-181 511.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1XH2N@135619|Oceanospirillales 135619|Oceanospirillales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_13085_5 1278309.KB907101_gene639 1.17e-122 359.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XH2C@135619|Oceanospirillales 135619|Oceanospirillales M mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_13782_1 1149133.ppKF707_5410 7.45e-38 133.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1YJAG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_17980_1 1288826.MSNKSG1_11553 1.1e-302 827.0 COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,1RNSS@1236|Gammaproteobacteria,464N5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) astB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009015,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.23 ko:K01484 ko00330,ko01100,map00330,map01100 - R04189 RC00024 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_2463,iECSP_1301.ECSP_2313,iECs_1301.ECs2451,iG2583_1286.G2583_2191 AstB k141_17980_2 1288826.MSNKSG1_11548 1.09e-86 263.0 COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,466V6@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily astE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009017,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_813,iECABU_c1320.ECABU_c20010,iECED1_1282.ECED1_1946,iECOK1_1307.ECOK1_1864,iECS88_1305.ECS88_1796,iUMN146_1321.UM146_08430,iUTI89_1310.UTI89_C1939,ic_1306.c2144 AstE_AspA k141_12412_1 999423.HMPREF9161_00117 1.38e-22 101.0 COG0726@1|root,COG0726@2|Bacteria,1UYYJ@1239|Firmicutes,4H3MV@909932|Negativicutes 909932|Negativicutes G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_22108_1 90814.KL370891_gene53 2.34e-38 142.0 COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,1SSUB@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - - - - - - - - - - Phosphonate-bd k141_4722_1 1288826.MSNKSG1_15886 9.19e-208 574.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,464KV@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yigM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - EamA k141_4722_2 1288826.MSNKSG1_15881 0.0 880.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,464IA@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_4722_3 1288826.MSNKSG1_15876 7.25e-231 637.0 COG2199@1|root,COG3706@2|Bacteria,1R7V7@1224|Proteobacteria,1RYGS@1236|Gammaproteobacteria,466RP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_18618_1 1278309.KB907113_gene3326 1.56e-116 368.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_15117_1 1288826.MSNKSG1_01623 2.75e-116 337.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,4674U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the MtfA family mtfA GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_15117_2 1288826.MSNKSG1_01628 1.46e-99 289.0 COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,4685Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S integral membrane protein - - - - - - - - - - - - CopD k141_15117_3 1288826.MSNKSG1_01638 9.43e-176 493.0 arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,1S209@1236|Gammaproteobacteria,466KG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15117_4 1288826.MSNKSG1_01643 0.0 930.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,46423@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains norR - - ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_15117_5 1288826.MSNKSG1_01648 1.45e-280 767.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1MV41@1224|Proteobacteria,1RMPJ@1236|Gammaproteobacteria,4668F@72275|Alteromonadaceae 1236|Gammaproteobacteria C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_6711_1 1122599.AUGR01000010_gene1097 1.28e-29 115.0 COG1226@1|root,COG1226@2|Bacteria,1R97G@1224|Proteobacteria,1RQAR@1236|Gammaproteobacteria,1XS1M@135619|Oceanospirillales 135619|Oceanospirillales P Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - - k141_6711_2 748658.KB907315_gene2564 2.28e-44 158.0 COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,1WX8G@135613|Chromatiales 135613|Chromatiales N PFAM OmpA MotB domain protein - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_6711_3 187272.Mlg_1397 1.14e-80 251.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,1WX44@135613|Chromatiales 135613|Chromatiales N PFAM MotA TolQ ExbB proton channel - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_7490_1 247633.GP2143_14466 2.54e-92 278.0 COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,1J9FX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S DUF1338 - - - - - - - - - - - - DUF1338 k141_6048_1 1278309.KB907105_gene1497 4.72e-57 187.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XIT5@135619|Oceanospirillales 135619|Oceanospirillales S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_6048_2 1278309.KB907105_gene1496 5.02e-214 597.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1XHM6@135619|Oceanospirillales 135619|Oceanospirillales S Permease lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_6048_3 1278309.KB907105_gene1495 7.14e-96 293.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XH34@135619|Oceanospirillales 135619|Oceanospirillales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_3959_1 644107.SL1157_0921 1.69e-123 361.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2TT8F@28211|Alphaproteobacteria,4NBFQ@97050|Ruegeria 28211|Alphaproteobacteria G Periplasmic binding protein domain - - - ko:K10552 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - Peripla_BP_4 k141_11661_1 1278309.KB907102_gene88 6.32e-172 494.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1XI4T@135619|Oceanospirillales 135619|Oceanospirillales P iron ABC transporter permease - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_2578_1 1168067.JAGP01000001_gene1454 4.12e-08 55.8 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,460BA@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_2578_2 297246.lpp1346 2.11e-26 97.8 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1JF7R@118969|Legionellales 118969|Legionellales J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_2578_3 216595.PFLU_4709 4.83e-17 80.5 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1YP0G@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Uncharacterized ACR, COG1399 yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 k141_9493_1 391165.GbCGDNIH1_0703 8.75e-40 144.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2JQ6Q@204441|Rhodospirillales 204441|Rhodospirillales E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 k141_17982_1 1122917.KB899661_gene936 1.62e-51 181.0 COG0154@1|root,COG0154@2|Bacteria,1TSAQ@1239|Firmicutes,4HDD7@91061|Bacilli,26RPR@186822|Paenibacillaceae 91061|Bacilli J Allophanate hydrolase - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_1248_3 1027273.GZ77_01765 2.49e-162 461.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XHPA@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_3325_1 396588.Tgr7_2204 2.06e-154 443.0 COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,1RY3C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM k141_3325_2 713587.THITH_00815 8.86e-79 248.0 COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,1S74G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_11777_1 765910.MARPU_07155 4.61e-66 207.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1WWJ3@135613|Chromatiales 135613|Chromatiales N basal body rod protein - - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_11777_2 211586.SO_3245 3.7e-60 194.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,2Q983@267890|Shewanellaceae 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_6242_1 1278309.KB907105_gene1492 9.96e-106 330.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XH2S@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_9013_1 1288826.MSNKSG1_08238 0.0 937.0 COG2518@1|root,COG2804@1|root,COG2518@2|Bacteria,COG2804@2|Bacteria,1R5CG@1224|Proteobacteria,1RV00@1236|Gammaproteobacteria,469V8@72275|Alteromonadaceae 1236|Gammaproteobacteria NOU Type II secretion system (T2SS), protein E, N-terminal domain - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - PCMT,T2SSE,T2SSE_N k141_7647_2 1121935.AQXX01000141_gene2070 5.54e-27 103.0 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,1XMGS@135619|Oceanospirillales 135619|Oceanospirillales S PilZ domain - - - - - - - - - - - - PilZ k141_7647_3 666681.M301_0510 2.13e-26 107.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KN77@206350|Nitrosomonadales 206350|Nitrosomonadales T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_2044_2 1288826.MSNKSG1_11753 2.04e-97 291.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,465QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k141_20843_1 1120919.AUBI01000002_gene1356 7.16e-17 83.6 2E5T9@1|root,330HK@2|Bacteria,1N9RB@1224|Proteobacteria,2UHDB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Sulfotransfer_2 k141_20843_2 1278309.KB907102_gene10 2.16e-175 501.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1XHA3@135619|Oceanospirillales 135619|Oceanospirillales M COG2148 Sugar transferases involved in lipopolysaccharide synthesis wcaJ - 2.7.8.40 ko:K03606,ko:K21303 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - - - Bac_transf,CoA_binding_3 k141_2752_1 1123511.KB905872_gene1845 2.57e-79 251.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H53T@909932|Negativicutes 909932|Negativicutes L RNA-directed DNA polymerase - - - - - - - - - - - - GIIM,RVT_1 k141_7648_1 1122134.KB893650_gene567 3.45e-91 284.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XH9N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_17387_1 1442599.JAAN01000021_gene2269 5.41e-30 123.0 COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria,1X40J@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_17387_2 1269813.ATUL01000045_gene1265 4.56e-30 110.0 COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS,STAS_2 k141_17387_3 595536.ADVE02000001_gene3451 2.61e-15 77.0 COG0745@1|root,COG2199@1|root,COG4251@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1R7HC@1224|Proteobacteria,2TWNT@28211|Alphaproteobacteria,36ZH0@31993|Methylocystaceae 28211|Alphaproteobacteria T Protoglobin - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Protoglobin,Response_reg k141_9014_1 472759.Nhal_1712 3.89e-130 387.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales 1236|Gammaproteobacteria F PFAM glycosyl transferase family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_9667_1 765913.ThidrDRAFT_2524 8.1e-120 363.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_2753_2 1255043.TVNIR_2976 2.15e-35 124.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1WY7Q@135613|Chromatiales 135613|Chromatiales S PFAM Fe-S metabolism associated - - - ko:K02426 - - - - ko00000 - - - SufE k141_2045_1 207954.MED92_12871 1.89e-63 218.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_6243_2 236097.ADG881_2642 1.81e-36 142.0 COG3528@1|root,COG3528@2|Bacteria,1R8GM@1224|Proteobacteria,1RZ6R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2219) - - - - - - - - - - - - DUF2219 k141_676_1 1538295.JY96_16965 1.12e-47 194.0 COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales 28216|Betaproteobacteria MQU Domain of unknown function (DUF4347) - - - - - - - - - - - - DUF4347 k141_9015_1 666681.M301_0245 5.16e-130 385.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,2KNSE@206350|Nitrosomonadales 206350|Nitrosomonadales I PLD-like domain - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_17388_1 1318628.MARLIPOL_14655 4.53e-109 338.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S1KB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_2754_1 1163617.SCD_n01931 5.79e-55 179.0 COG1595@1|root,COG1595@2|Bacteria,1RKQH@1224|Proteobacteria,2VSYG@28216|Betaproteobacteria 28216|Betaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_2046_1 367336.OM2255_07970 7.85e-68 228.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_2046_2 759362.KVU_2112 2.18e-22 95.5 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_6817_1 225937.HP15_757 1.16e-199 562.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_6817_2 1288826.MSNKSG1_01173 3.92e-178 498.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,46700@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, permease component ypjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C_asm k141_6817_3 1288826.MSNKSG1_01168 5.92e-297 811.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,464AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorB yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_6817_4 1288826.MSNKSG1_01163 1.02e-265 744.0 COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria,465VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_6244_1 69328.PVLB_22380 2.76e-131 385.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_15228_1 1288826.MSNKSG1_04811 4.02e-196 546.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,1RR1N@1236|Gammaproteobacteria,469WK@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, periplasmic component - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_15228_2 1288826.MSNKSG1_04806 6.7e-190 530.0 COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,1RY3E@1236|Gammaproteobacteria,46430@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the binding-protein-dependent transport system permease family - - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 k141_15228_3 1288826.MSNKSG1_04801 4.21e-51 167.0 COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,1RSNT@1236|Gammaproteobacteria,46603@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, ATPase component ecfA2 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_9016_1 710687.KI912270_gene4471 1.62e-21 92.4 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,23999@1762|Mycobacteriaceae 201174|Actinobacteria K Rhodanese-like domain - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese k141_9668_1 1224136.AMFN01000023_gene1893 2.78e-156 462.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,283B8@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria L UvrD-like helicase C-terminal domain uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_2047_1 1298593.TOL_3421 2.17e-58 194.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XIS2@135619|Oceanospirillales 135619|Oceanospirillales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_17390_1 351348.Maqu_0077 1.58e-114 337.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,46A3E@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family speC - 4.1.1.17,4.1.1.20 ko:K01581,ko:K01586 ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230 M00016,M00134,M00525,M00526,M00527 R00451,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0864 Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_9017_1 1538295.JY96_03475 5.82e-22 99.8 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VJS8@28216|Betaproteobacteria 28216|Betaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_677_1 1163617.SCD_n01519 5.84e-76 231.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria 28216|Betaproteobacteria T CBS domain containing protein - - - ko:K07168 - - - - ko00000 - - - CBS,HPP k141_677_2 765913.ThidrDRAFT_3973 9.55e-82 249.0 COG3448@1|root,COG3448@2|Bacteria,1QHBG@1224|Proteobacteria,1S7QY@1236|Gammaproteobacteria,1WYGM@135613|Chromatiales 135613|Chromatiales T PFAM CBS domain - - - - - - - - - - - - CBS k141_6245_1 367336.OM2255_11075 2.89e-167 475.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_2756_1 414684.RC1_1068 5.1e-11 65.9 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,2JPR6@204441|Rhodospirillales 204441|Rhodospirillales H Probable molybdopterin binding domain - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_2756_2 439497.RR11_1804 5.47e-56 185.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria,4NBHQ@97050|Ruegeria 28211|Alphaproteobacteria O XdhC and CoxI family MA20_09415 - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_14552_1 1288826.MSNKSG1_09083 1.3e-238 657.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,464Y6@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1077 Actin-like ATPase involved in cell morphogenesis mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_14552_2 1288826.MSNKSG1_09078 1.05e-161 455.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,464KN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_14552_3 1288826.MSNKSG1_09073 2.8e-105 304.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,468E3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_19490_1 545276.KB898732_gene2480 1.19e-171 486.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_19490_3 572477.Alvin_0678 4.15e-45 155.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,1WWFD@135613|Chromatiales 135613|Chromatiales K PFAM Cyclic nucleotide-binding - - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_14553_1 243233.MCA3085 1.8e-83 257.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_6820_2 1123247.AUIJ01000001_gene1782 5.07e-55 182.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_20844_1 553385.JEMF01000081_gene2055 1.3e-20 99.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XHGK@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA - 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_20844_2 1232437.KL662016_gene1204 1.49e-53 176.0 COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42R8D@68525|delta/epsilon subdivisions,2WN83@28221|Deltaproteobacteria,2MJPW@213118|Desulfobacterales 28221|Deltaproteobacteria J SpoU rRNA Methylase family trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_20844_3 104355.XP_007861218.1 9.78e-08 55.1 COG0607@1|root,KOG1530@2759|Eukaryota,3A884@33154|Opisthokonta,3P5AA@4751|Fungi,3VBYR@5204|Basidiomycota,22F1W@155619|Agaricomycetes,3H8RI@355688|Agaricomycetes incertae sedis 4751|Fungi P Rhodanese Homology Domain RDL2 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0012505,GO:0016020,GO:0016740,GO:0016782,GO:0016783,GO:0019867,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0098588,GO:0098805 - - - - - - - - - - Rhodanese k141_6246_2 743299.Acife_1818 1.6e-94 290.0 COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,2NC25@225057|Acidithiobacillales 225057|Acidithiobacillales S 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 k141_679_1 883126.HMPREF9710_03743 1.66e-06 47.0 2EHWE@1|root,33BMZ@2|Bacteria,1NGH4@1224|Proteobacteria,2VY0S@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative motility protein - - - - - - - - - - - - YjfB_motility k141_679_2 90813.JQMT01000001_gene1233 6.82e-13 67.4 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_19491_1 1123070.KB899258_gene1877 9.98e-29 118.0 COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase WecB/TagA/CpsF family - - - - - - - - - - - - Glyco_tran_WecB k141_2050_1 1163409.UUA_11943 4.73e-71 238.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X4ZZ@135614|Xanthomonadales 135614|Xanthomonadales T GGDEF domain - - - - - - - - - - - - EAL,GAF_2,GGDEF k141_9019_1 990285.RGCCGE502_22320 6.33e-72 239.0 COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria,4BAZE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_9670_1 1232683.ADIMK_0636 1.71e-31 124.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,465CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2200 FOG EAL domain - - 3.1.4.52 ko:K20963 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - CBS,EAL,GGDEF k141_9670_2 1278309.KB907100_gene1894 5.55e-105 306.0 COG2365@1|root,COG2365@2|Bacteria,1RGE7@1224|Proteobacteria,1SBQH@1236|Gammaproteobacteria,1XPA6@135619|Oceanospirillales 135619|Oceanospirillales T Tyrosine phosphatase family - - - - - - - - - - - - Y_phosphatase2 k141_17392_1 665029.EAMY_3683 9.53e-88 274.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,3X4GW@551|Erwinia 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_17392_2 765913.ThidrDRAFT_2150 3.79e-60 200.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_14554_1 1305737.JAFX01000001_gene144 2.97e-14 66.2 29AQG@1|root,2ZXQ8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_680_1 1125973.JNLC01000010_gene1339 7.92e-29 107.0 COG2246@1|root,COG2246@2|Bacteria,1NA3W@1224|Proteobacteria,2UGKB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GtrA-like protein - - - - - - - - - - - - GtrA k141_6247_1 472759.Nhal_2016 4.89e-91 278.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX16@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_6247_2 1265503.KB905162_gene3491 1.15e-45 155.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1RPVE@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Spermidine synthase - - - - - - - - - - - - Spermine_synth k141_15230_1 765914.ThisiDRAFT_0385 2.38e-10 60.5 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1WW7C@135613|Chromatiales 135613|Chromatiales E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_15230_2 522306.CAP2UW1_2047 2.23e-169 503.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,1KPQD@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_9699_1 617140.AJZE01000036_gene2906 1.9e-79 269.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales 135623|Vibrionales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_9699_2 1396858.Q666_16530 1.85e-60 196.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,465RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_15253_1 439235.Dalk_2075 2.82e-30 124.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MMRD@213118|Desulfobacterales 28221|Deltaproteobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3 k141_6858_1 1173024.KI912152_gene508 2.38e-70 220.0 COG3316@1|root,COG3316@2|Bacteria,1G3EB@1117|Cyanobacteria 1117|Cyanobacteria L COG3316 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_IS240 k141_20095_2 1216007.AOPM01000012_gene71 1.19e-60 189.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,2Q2CI@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_20095_3 1116472.MGMO_25c00400 8.03e-73 242.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XDPM@135618|Methylococcales 135618|Methylococcales T Signal transduction histidine kinase, phosphotransfer (Hpt) region - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_20878_2 666681.M301_0194 2.03e-79 246.0 COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria 28216|Betaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - - k141_2084_1 443152.MDG893_09696 1.97e-09 57.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k141_2084_2 59538.XP_005976936.1 5.41e-14 75.5 COG0147@1|root,KOG1223@2759|Eukaryota,38FJ5@33154|Opisthokonta 33154|Opisthokonta E anthranilate synthase activity TRP2 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_20096_1 317025.Tcr_0434 4.4e-83 258.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S7I9@1236|Gammaproteobacteria 1236|Gammaproteobacteria M MacB-like periplasmic core domain VPA0559 - - - - - - - - - - - FtsX,MacB_PCD k141_20096_2 1348657.M622_08275 0.000286 42.7 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VQWS@28216|Betaproteobacteria,2KU68@206389|Rhodocyclales 28216|Betaproteobacteria V ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs - - - - - - - - - - - - ABC_tran k141_14607_2 1469613.JT55_16650 4.13e-90 271.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TT48@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_6380_1 1049564.TevJSym_ag01090 2.83e-87 280.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1J526@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_11982_2 1278309.KB907106_gene1359 2.56e-199 555.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XHBV@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_12663_1 243159.AFE_1664 2.8e-88 272.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,2NC9T@225057|Acidithiobacillales 225057|Acidithiobacillales C FAD binding domain glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_12663_2 314345.SPV1_08466 2.09e-112 336.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria 1224|Proteobacteria C PFAM FAD linked oxidase domain protein glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 FAD-oxidase_C,FAD_binding_4 k141_1492_1 1348657.M622_09200 8.08e-08 54.7 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_1492_2 1278309.KB907106_gene1273 9.55e-124 374.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XHDN@135619|Oceanospirillales 135619|Oceanospirillales FP Belongs to the GppA Ppx family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_9156_1 1278309.KB907099_gene2614 4.4e-61 201.0 COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria,1XHV4@135619|Oceanospirillales 135619|Oceanospirillales C one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high narH - 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Fer4_11,Nitr_red_bet_C k141_9156_2 1278309.KB907099_gene2615 1.08e-142 406.0 COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,1RQ23@1236|Gammaproteobacteria,1XJCX@135619|Oceanospirillales 135619|Oceanospirillales C Nitrate reductase delta subunit narJ - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - - Nitrate_red_del k141_9156_3 1278309.KB907099_gene2616 4.96e-145 410.0 COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,1RPTD@1236|Gammaproteobacteria,1XHW8@135619|Oceanospirillales 135619|Oceanospirillales C one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high narI - 1.7.5.1 ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Nitrate_red_gam k141_9156_4 1278309.KB907099_gene2617 2.44e-151 430.0 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1S2D7@1236|Gammaproteobacteria,1XRIB@135619|Oceanospirillales 135619|Oceanospirillales O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_9156_5 998088.B565_3680 5.91e-95 283.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1Y3SW@135624|Aeromonadales 135624|Aeromonadales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_9156_6 1278309.KB907099_gene2619 3.38e-211 587.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XHTC@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_9156_7 1278309.KB907099_gene2620 2.69e-120 348.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,1XMH7@135619|Oceanospirillales 135619|Oceanospirillales T helix_turn_helix, cAMP Regulatory protein - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_9156_8 626887.J057_13461 7.41e-42 142.0 COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,1S936@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zinc-binding protein - - - - - - - - - - - - DGC k141_9156_9 1278309.KB907099_gene2621 3.64e-73 223.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XMRF@135619|Oceanospirillales 135619|Oceanospirillales H Probable molybdopterin binding domain - - - - - - - - - - - - MoCF_biosynth k141_17519_1 207954.MED92_15053 5.03e-97 292.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XMZH@135619|Oceanospirillales 135619|Oceanospirillales P Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_4293_1 396588.Tgr7_0666 7.99e-106 314.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity - - 3.1.1.45,3.1.1.76 ko:K01061,ko:K22249 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_4293_2 314345.SPV1_12220 1.48e-182 516.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria 1224|Proteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2375 DAHP_synth_1 k141_4293_3 1397527.Q670_03110 6.73e-37 143.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9 k141_21692_1 1177928.TH2_20166 3.88e-10 60.8 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2JR96@204441|Rhodospirillales 204441|Rhodospirillales E aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_21692_2 1328313.DS2_00260 1.36e-65 203.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,467BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 k141_11306_2 1288826.MSNKSG1_13617 7.5e-236 649.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464DU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_11306_3 1318628.MARLIPOL_09666 4.92e-207 577.0 COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,46446@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0798 Arsenite efflux pump ACR3 and related permeases arsB - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF k141_4980_7 270374.MELB17_08841 4.99e-227 637.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_4980_8 1046724.KB889877_gene1519 1.81e-278 766.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_4980_9 1046724.KB889877_gene1518 4.09e-81 243.0 COG3090@1|root,COG3090@2|Bacteria 2|Bacteria G Trap-type c4-dicarboxylate transport system, small permease component MA20_30165 - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ k141_4980_10 270374.MELB17_08826 4.42e-205 572.0 COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,1RZWY@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_4980_11 1121943.KB899995_gene834 2.16e-100 297.0 COG1802@1|root,COG1802@2|Bacteria,1RBIC@1224|Proteobacteria,1S276@1236|Gammaproteobacteria,1XPFD@135619|Oceanospirillales 135619|Oceanospirillales K FCD - - - - - - - - - - - - FCD,GntR k141_4980_12 1288826.MSNKSG1_02323 1.31e-290 792.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,46CEQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_4980_13 1288826.MSNKSG1_02318 1.43e-192 536.0 COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,1RSCS@1236|Gammaproteobacteria,465CE@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_4980_14 1288826.MSNKSG1_02313 0.0 895.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4647I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_4980_15 1288826.MSNKSG1_02308 3.93e-289 791.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,466H2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_21101_1 667015.Bacsa_0617 1.84e-32 121.0 COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,2FPZZ@200643|Bacteroidia,4AKXV@815|Bacteroidaceae 976|Bacteroidetes S TIGR02453 family - - - - - - - - - - - - DUF2461 k141_21708_1 357804.Ping_0269 1.38e-10 58.5 2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1840) VPA1132 - - - - - - - - - - - DUF1840 k141_21708_2 365044.Pnap_3370 1.61e-53 175.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,4ADHB@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM Hly-III family protein hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_16148_1 1278309.KB907102_gene16 1.93e-125 374.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XIEY@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 k141_2918_1 1282876.BAOK01000001_gene1149 3.82e-33 127.0 COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,2TTTR@28211|Alphaproteobacteria,4BS8V@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system hmuV - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_11317_1 857087.Metme_4425 1.59e-58 191.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XEJR@135618|Methylococcales 135618|Methylococcales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_14788_1 1027273.GZ77_12535 1.72e-21 94.4 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria,1XM0V@135619|Oceanospirillales 135619|Oceanospirillales D cell division protein - - - - - - - - - - - - SPOR k141_14788_2 2340.JV46_16790 2.32e-17 80.9 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1J5IS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_10595_1 926569.ANT_27630 5.27e-08 53.9 COG2920@1|root,COG2920@2|Bacteria,2G9BI@200795|Chloroflexi 200795|Chloroflexi P DsrC like protein dsrC - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_10595_2 329726.AM1_2737 1.43e-19 86.3 COG2105@1|root,COG2105@2|Bacteria,1GGD4@1117|Cyanobacteria 1117|Cyanobacteria S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT k141_10595_3 768671.ThimaDRAFT_4186 2.01e-40 140.0 2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,1SJ45@1236|Gammaproteobacteria,1X0T7@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_6391_1 1123514.KB905899_gene1734 7.59e-69 213.0 COG0778@1|root,COG0778@2|Bacteria,1RBZQ@1224|Proteobacteria,1S328@1236|Gammaproteobacteria,460X0@72273|Thiotrichales 72273|Thiotrichales C Oxygen-insensitive NAD(P)H nitroreductase Dihydropteridine reductase - - - - - - - - - - - - Nitroreductase k141_19642_1 439496.RBY4I_1126 1.54e-81 256.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_11998_2 1121937.AUHJ01000010_gene1726 9.99e-12 65.9 COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,466MU@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo k141_9868_1 1250005.PHEL85_2143 1.15e-62 202.0 COG3301@1|root,COG3301@2|Bacteria,4NITJ@976|Bacteroidetes,1I0XA@117743|Flavobacteriia 976|Bacteroidetes P Polysulphide reductase, NrfD - - - - - - - - - - - - NrfD k141_18256_2 666686.B1NLA3E_07575 6.98e-25 99.0 2CH44@1|root,30Q8S@2|Bacteria,1U00Q@1239|Firmicutes,4IC9V@91061|Bacilli,1ZK9S@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_15503_1 1089547.KB913013_gene1547 3.84e-63 209.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47JDQ@768503|Cytophagia 976|Bacteroidetes J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_7821_1 519989.ECTPHS_11230 7.82e-19 86.7 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_12677_2 1122197.ATWI01000011_gene452 1.14e-26 99.0 2EMNU@1|root,33FB8@2|Bacteria,1NNXU@1224|Proteobacteria,1SJAS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16861_1 717231.Flexsi_0440 1.44e-52 177.0 COG3547@1|root,COG3547@2|Bacteria 2|Bacteria L Transposase (IS116 IS110 IS902 family) - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_1517_2 666685.R2APBS1_2614 6.96e-62 199.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1X5K2@135614|Xanthomonadales 135614|Xanthomonadales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 k141_13385_1 1121921.KB898706_gene2694 0.000474 42.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,2PNYS@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L Uncharacterised protein family UPF0102 yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_13385_2 1207076.ALAT01000187_gene2874 3.3e-83 251.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1Z0IQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_98_1 329726.AM1_4814 3.04e-19 83.6 COG3576@1|root,COG3576@2|Bacteria,1G5D9@1117|Cyanobacteria 1117|Cyanobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_21102_1 1469613.JT55_06745 1.35e-13 67.0 COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria,3FDG4@34008|Rhodovulum 28211|Alphaproteobacteria O Disulfide bond formation protein DsbB dsbB - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_21102_2 985054.JQEZ01000005_gene252 5.34e-50 164.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria,4NA6T@97050|Ruegeria 28211|Alphaproteobacteria S SNARE associated Golgi protein dedA - - - - - - - - - - - SNARE_assoc k141_10596_2 697282.Mettu_2820 2.71e-45 151.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1XF7S@135618|Methylococcales 135618|Methylococcales T low molecular weight - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_3627_1 1121479.AUBS01000003_gene4146 1.38e-70 237.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_18970_1 521011.Mpal_0355 7.36e-30 115.0 arCOG08055@1|root,arCOG08055@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - Methyltransf_11 k141_14789_1 1123518.ARWI01000001_gene1194 2.91e-79 254.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales 72273|Thiotrichales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_14078_2 388919.SSA_0710 1.18e-10 65.5 COG0110@1|root,COG1216@1|root,COG0110@2|Bacteria,COG1216@2|Bacteria,1UVBQ@1239|Firmicutes,4I3BN@91061|Bacilli,1WRKI@1305|Streptococcus sanguinis 91061|Bacilli S Glycosyl transferases group 1 epsH - - - - - - - - - - - Hexapep k141_11318_1 675812.VHA_001610 9.94e-22 90.5 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,1XTMW@135623|Vibrionales 135623|Vibrionales S nucleoprotein polynucleotide-associated enzyme yaiL - - ko:K09912 - - - - ko00000 - - - DUF2058 k141_11318_2 34506.g6040 1.02e-10 66.2 COG0642@1|root,COG1025@1|root,COG5641@1|root,KOG0519@2759|Eukaryota,KOG0959@2759|Eukaryota,KOG1601@2759|Eukaryota,3AGK5@33154|Opisthokonta,3BXQF@33208|Metazoa,3DDEZ@33213|Bilateria 33208|Metazoa K Sigma-54 interaction domain - - - - - - - - - - - - Response_reg,Sigma54_activat k141_21710_1 1123237.Salmuc_02307 3.34e-39 135.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2U93G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB k141_13386_1 1237149.C900_01985 2.71e-74 236.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40 k141_4315_1 349124.Hhal_1922 3.68e-51 174.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1WWFW@135613|Chromatiales 135613|Chromatiales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_4315_2 1123367.C666_05880 8.35e-15 73.9 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VI8U@28216|Betaproteobacteria 28216|Betaproteobacteria HP Abc transporter - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran,Mg_chelatase k141_9170_1 1196031.ALEG01000047_gene245 1.03e-09 62.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4HB7U@91061|Bacilli,1ZEBW@1386|Bacillus 91061|Bacilli S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_9170_2 491952.Mar181_1005 7.35e-17 81.3 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1S1G2@1236|Gammaproteobacteria,1XN8X@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_15504_1 314282.PCNPT3_00445 1.12e-91 281.0 28I8U@1|root,2Z8BM@2|Bacteria,1R8BF@1224|Proteobacteria,1S6BC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Beta protein - - - - - - - - - - - - Beta_protein k141_11999_2 247634.GPB2148_624 1.13e-62 198.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1J5T9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_10597_1 261292.Nit79A3_1583 4.2e-112 334.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2W9B6@28216|Betaproteobacteria,372NE@32003|Nitrosomonadales 28216|Betaproteobacteria C alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_8496_1 1278309.KB907102_gene46 2.51e-56 177.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XKFH@135619|Oceanospirillales 135619|Oceanospirillales S Stringent starvation protein B sspB - - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_8496_2 1278309.KB907102_gene45 1.69e-149 421.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XI89@135619|Oceanospirillales 135619|Oceanospirillales O Stringent starvation protein A sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_8496_3 1278309.KB907102_gene44 8.79e-119 344.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1XHE5@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_7103_1 298386.PBPRB0645 5.54e-51 179.0 COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria 1224|Proteobacteria C COG0348 Polyferredoxin vnfA - - - - - - - - - - - Fer4_5 k141_19644_1 571166.KI421509_gene4161 2.37e-119 359.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily sulP - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_21711_1 1288826.MSNKSG1_16576 1.57e-109 325.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_11319_2 412597.AEPN01000015_gene1208 2.25e-12 68.9 COG1359@1|root,COG3153@1|root,COG1359@2|Bacteria,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UG08@28211|Alphaproteobacteria,2PVNY@265|Paracoccus 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - ko:K03824 - - - - ko00000,ko01000 - - - ABM,Acetyltransf_1,Acetyltransf_7,Acetyltransf_9 k141_21242_1 396588.Tgr7_0999 1.83e-49 172.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_3771_1 1158182.KB905020_gene1906 3.07e-81 253.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,1X02W@135613|Chromatiales 135613|Chromatiales L Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM k141_5860_1 1385515.N791_04640 1.17e-24 101.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1X5BW@135614|Xanthomonadales 135614|Xanthomonadales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA k141_6507_1 1278309.KB907102_gene233 5.41e-82 244.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,1XKHM@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0260 family - - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_6507_2 1278309.KB907102_gene232 4.53e-47 152.0 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1XKZ7@135619|Oceanospirillales 135619|Oceanospirillales S YcgL domain-containing protein - - - ko:K09902 - - - - ko00000 - - - YcgL k141_6507_3 1278309.KB907102_gene231 5.22e-116 342.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XIUE@135619|Oceanospirillales 135619|Oceanospirillales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_979_1 246197.MXAN_6586 5.62e-19 92.4 COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,42PS5@68525|delta/epsilon subdivisions 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_4,Response_reg k141_5139_1 335543.Sfum_1083 1.65e-112 329.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WJE9@28221|Deltaproteobacteria,2MQA4@213462|Syntrophobacterales 28221|Deltaproteobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_21903_1 1168067.JAGP01000001_gene1912 6.09e-28 109.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,45ZVT@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_21903_2 1168067.JAGP01000001_gene1913 9.16e-56 182.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,46181@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the conversion of dihydroorotate to orotate pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_7991_1 1232683.ADIMK_4111 1.4e-151 444.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA k141_16277_1 216595.PFLU_3971A 3.05e-05 53.5 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria 1224|Proteobacteria L transposase IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_276_1 1278309.KB907102_gene111 8.1e-84 250.0 COG0790@1|root,COG0790@2|Bacteria,1NEQR@1224|Proteobacteria,1S7XV@1236|Gammaproteobacteria,1XKTU@135619|Oceanospirillales 135619|Oceanospirillales S Sel1-like repeats. - - - - - - - - - - - - Sel1 k141_276_2 1278309.KB907102_gene112 3.73e-142 415.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 k141_7264_1 999541.bgla_1g09860 1.42e-48 170.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,1K4ET@119060|Burkholderiaceae 28216|Betaproteobacteria G sorbosone dehydrogenase - - - - - - - - - - - - GSDH,SGL k141_7264_2 697282.Mettu_0698 1.65e-78 245.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales 135618|Methylococcales IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_10003_1 1168067.JAGP01000001_gene220 4.94e-11 60.5 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,46180@72273|Thiotrichales 72273|Thiotrichales S Belongs to the PsiE family - - - ko:K13256 - - - - ko00000 - - - PsiE k141_10003_2 90813.JQMT01000001_gene180 2.34e-31 115.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,46063@72273|Thiotrichales 72273|Thiotrichales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_18404_1 1278309.KB907100_gene2218 1.72e-210 591.0 COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_3,HlyD_D23,OEP k141_18404_2 1278309.KB907100_gene2219 0.0 1293.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria,1XNWG@135619|Oceanospirillales 135619|Oceanospirillales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_18404_3 1278309.KB907100_gene2220 7.2e-14 69.3 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,1XR7H@135619|Oceanospirillales 135619|Oceanospirillales V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_3772_1 352165.HMPREF7215_0570 3.7e-27 111.0 COG1219@1|root,COG1219@2|Bacteria,3TA2N@508458|Synergistetes 508458|Synergistetes O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_15622_1 1547437.LL06_05055 8.98e-53 185.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,43JFR@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_15622_2 1231190.NA8A_18602 2.46e-115 335.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,43J9P@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V COG1136 ABC-type antimicrobial peptide transport system ATPase component - - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran k141_12137_1 1249480.B649_07390 2.47e-121 404.0 COG2304@1|root,COG4932@1|root,COG5295@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1QU09@1224|Proteobacteria,43DI2@68525|delta/epsilon subdivisions 1224|Proteobacteria M von Willebrand factor (vWF) type A domain - - - - - - - - - - - - Calx-beta,HemolysinCabind,VWA_2 k141_12137_2 1278309.KB907101_gene280 4.01e-10 59.3 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_17728_1 1461693.ATO10_04607 4.13e-42 144.0 COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2U5M6@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the globin family MA20_17055 - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - Globin k141_17728_2 998674.ATTE01000001_gene3726 5.24e-43 155.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,45ZRS@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM nitrite reductase NAD(P)H , large subunit - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_4495_1 396588.Tgr7_2953 9.44e-102 310.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales 135613|Chromatiales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_4495_2 314345.SPV1_02172 4.1e-125 367.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria 1224|Proteobacteria O Heat shock protein DnaJ domain protein cbpA - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_4495_3 395493.BegalDRAFT_2992 1.56e-57 182.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,4613N@72273|Thiotrichales 72273|Thiotrichales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_4495_4 521719.ATXQ01000006_gene1357 6.6e-252 710.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1YEIQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_8635_1 1288826.MSNKSG1_07588 2.53e-111 333.0 COG2067@1|root,COG2067@2|Bacteria,1N0NZ@1224|Proteobacteria,1S0U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X k141_8635_2 1288826.MSNKSG1_07593 6.17e-236 649.0 COG3103@1|root,COG3103@2|Bacteria,1R4IV@1224|Proteobacteria,1RYIZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Sh3 type 3 domain protein - - - - - - - - - - - - Phenol_MetA_deg k141_8635_3 1288826.MSNKSG1_07598 1.28e-186 519.0 COG3271@1|root,COG3271@2|Bacteria,1R9HR@1224|Proteobacteria,1RYUR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase - - - ko:K06992 - - - - ko00000 - - - Peptidase_C39 k141_8635_4 1288826.MSNKSG1_07603 2.04e-312 856.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,46411@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_8635_5 1288826.MSNKSG1_07608 2.08e-144 407.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1SAV7@1236|Gammaproteobacteria,46CGT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_8635_6 1288826.MSNKSG1_07613 3.13e-273 749.0 COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,4665P@72275|Alteromonadaceae 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_3,HlyD_D23,OEP k141_8635_7 1288826.MSNKSG1_07618 3.16e-89 283.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria,465XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21243_1 391616.OA238_c34150 2.44e-125 377.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_277_1 1163408.UU9_09377 9.58e-131 378.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1X3G9@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_9312_1 945550.VISI1226_11359 1.28e-09 57.8 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1XWX6@135623|Vibrionales 135623|Vibrionales N Flagellar protein FliS fliS GO:0003674,GO:0005198 - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_9312_2 1123518.ARWI01000001_gene621 1.09e-07 61.2 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,460Z0@72273|Thiotrichales 72273|Thiotrichales N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_5140_1 443152.MDG893_07680 3.41e-126 366.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1SNWW@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG4177 ABC-type branched-chain amino acid transport system, permease component - - - - - - - - - - - - BPD_transp_2 k141_5140_2 270374.MELB17_00840 6.9e-45 152.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1SZ2D@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - - - - - - - - - - BPD_transp_2 k141_7993_1 870187.Thini_1074 4.43e-102 314.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZPC@72273|Thiotrichales 72273|Thiotrichales G PFAM alpha amylase, catalytic - - 2.4.1.4 ko:K05341 ko00500,map00500 - R01823 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_3094_1 795666.MW7_3315 1.86e-54 180.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1K1CF@119060|Burkholderiaceae 28216|Betaproteobacteria P Cytochrome C1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_3094_2 1122134.KB893651_gene1998 1.29e-58 193.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1XHEG@135619|Oceanospirillales 135619|Oceanospirillales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_19138_1 1122599.AUGR01000009_gene2423 1.39e-193 582.0 COG2207@1|root,COG3899@1|root,COG2207@2|Bacteria,COG3899@2|Bacteria,1MX23@1224|Proteobacteria,1SYG8@1236|Gammaproteobacteria,1XKV4@135619|Oceanospirillales 135619|Oceanospirillales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_12138_2 349124.Hhal_1925 4.2e-72 223.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X0W2@135613|Chromatiales 135613|Chromatiales S PFAM cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_12138_3 754476.Q7A_2813 0.000102 44.3 COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,461R0@72273|Thiotrichales 72273|Thiotrichales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_11450_2 1121921.KB898712_gene2126 1.73e-59 193.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,2PNH1@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_11450_3 1049564.TevJSym_aj00070 3.68e-47 160.0 COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SH3 domain protein - - - - - - - - - - - - OMP_b-brl,SH3_3,SH3_4 k141_3773_1 857087.Metme_0226 9.82e-26 109.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XEJJ@135618|Methylococcales 135618|Methylococcales S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn k141_3773_2 90814.KL370891_gene1298 1.63e-15 73.2 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria 1224|Proteobacteria K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_990_2 1449347.JQLN01000005_gene4055 0.00035 46.6 COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria,2M3HF@2063|Kitasatospora 201174|Actinobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_17747_1 323261.Noc_1879 1.93e-32 127.0 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria,1WWYQ@135613|Chromatiales 135613|Chromatiales O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_15636_2 1049564.TevJSym_ax00390 2.85e-62 195.0 COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1JBZG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_15636_3 713587.THITH_04060 1.56e-89 270.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1WWCR@135613|Chromatiales 135613|Chromatiales K response regulator receiver - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_15636_4 1255043.TVNIR_2713 6.29e-119 364.0 COG3850@1|root,COG3850@2|Bacteria,1R2CG@1224|Proteobacteria,1T5KV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 k141_10016_1 207954.MED92_02908 1.76e-154 439.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1XI7Y@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type nitrate sulfonate bicarbonate transport system, ATPase component nasD - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_3114_1 314256.OG2516_12386 2.53e-71 226.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2PCV0@252301|Oceanicola 28211|Alphaproteobacteria S Peptidogalycan biosysnthesis/recognition MA20_36195 - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_3114_2 89187.ISM_09005 6.73e-12 64.3 COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2TV1D@28211|Alphaproteobacteria,46PX1@74030|Roseovarius 28211|Alphaproteobacteria C COG0584 Glycerophosphoryl diester phosphodiesterase ugpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_6524_1 1249975.JQLP01000005_gene1064 3.22e-59 201.0 COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1HX80@117743|Flavobacteriia,2P6GD@244698|Gillisia 976|Bacteroidetes M Mur ligase family, glutamate ligase domain murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_4505_1 674977.VMC_28650 2.59e-147 425.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XV0G@135623|Vibrionales 135623|Vibrionales F carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_10017_1 1122925.KB895378_gene2538 9.78e-06 46.2 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,26SR4@186822|Paenibacillaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_15637_1 519989.ECTPHS_09954 3.38e-69 212.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria,1WXZR@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_15637_2 765910.MARPU_16060 1.04e-33 124.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1WWWY@135613|Chromatiales 135613|Chromatiales D Belongs to the TtcA family ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_17003_1 105559.Nwat_2085 5.39e-59 191.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1WXSE@135613|Chromatiales 135613|Chromatiales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_991_1 1278309.KB907103_gene1038 1.71e-101 299.0 COG5581@1|root,COG5581@2|Bacteria,1RJ1B@1224|Proteobacteria,1T0MN@1236|Gammaproteobacteria,1XRQT@135619|Oceanospirillales 135619|Oceanospirillales M Flagellar protein YcgR - - - - - - - - - - - - PilZ,YcgR_2 k141_991_2 94122.Shewana3_1471 1.35e-20 92.0 COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,2Q90J@267890|Shewanellaceae 1236|Gammaproteobacteria H PFAM ATP-NAD AcoX kinase - - - - - - - - - - - - NAD_kinase k141_10779_1 1288826.MSNKSG1_04741 3.17e-53 167.0 COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,1S8SP@1236|Gammaproteobacteria,46812@72275|Alteromonadaceae 1236|Gammaproteobacteria T Prokaryotic dksA/traR C4-type zinc finger ybiI - - - - - - - - - - - zf-dskA_traR k141_10779_2 1288826.MSNKSG1_04736 1.68e-74 224.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1S9P2@1236|Gammaproteobacteria,46BK2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Lytic transglycolase rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1 k141_20565_1 626887.J057_17785 5.57e-14 71.2 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,4670X@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase atuE - 4.2.1.57 ko:K13779 ko00281,map00281 - R03493 RC00941 ko00000,ko00001,ko01000 - - - ECH_1 k141_20565_2 1250232.JQNJ01000001_gene1602 3.41e-05 45.1 COG2608@1|root,COG2608@2|Bacteria,4NUWP@976|Bacteroidetes,1I5DZ@117743|Flavobacteriia 976|Bacteroidetes P Heavy metal transport detoxification protein - - - - - - - - - - - - HMA k141_20565_3 351348.Maqu_3291 3.49e-16 78.2 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,464C7@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0530 Ca2 Na antiporter Z012_08255 - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_11458_1 323261.Noc_1493 2.86e-129 389.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1WWJW@135613|Chromatiales 135613|Chromatiales S protease with the C-terminal PDZ domain - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_12855_2 1232683.ADIMK_4159 7.05e-72 218.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,46758@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_12855_3 1232683.ADIMK_1393 1.04e-57 189.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,4648K@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_21252_1 388399.SSE37_06609 1.56e-76 238.0 COG0697@1|root,COG0697@2|Bacteria,1MV7Y@1224|Proteobacteria,2TUVM@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_19150_1 1469245.JFBG01000001_gene536 4.46e-35 137.0 COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,1WXQ5@135613|Chromatiales 135613|Chromatiales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_19150_2 396588.Tgr7_0316 3.25e-61 194.0 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_3115_1 472759.Nhal_3420 1e-110 345.0 COG1674@1|root,COG3266@1|root,COG1674@2|Bacteria,COG3266@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales 135613|Chromatiales D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_3115_2 1163617.SCD_n01183 3.1e-19 85.9 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria 28216|Betaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA k141_17865_2 1385935.N836_17730 1.31e-15 77.4 COG2197@1|root,COG2197@2|Bacteria,1G1TZ@1117|Cyanobacteria,1H7FH@1150|Oscillatoriales 1117|Cyanobacteria K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain ycf29 - - - - - - - - - - - GerE,Response_reg k141_17865_3 1124991.MU9_2284 4.2e-11 62.4 COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,1S926@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Periplasmic or secreted lipoprotein osmY_1 - - ko:K04065 - - - - ko00000 - - - BON k141_17865_4 1121943.KB899990_gene3622 1.32e-55 188.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase - - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_15777_1 870187.Thini_3864 1.81e-62 194.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_15777_2 243233.MCA1868 2.62e-14 73.6 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XE0Q@135618|Methylococcales 135618|Methylococcales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_12991_1 1117318.PRUB_06360 4.58e-10 63.5 COG0457@1|root,COG0457@2|Bacteria,1R9GZ@1224|Proteobacteria,1RZID@1236|Gammaproteobacteria,2Q1TU@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - BBP2_2,DUF560,TPR_19 k141_1132_1 768066.HELO_2645 5.9e-32 129.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12316_2 1122194.AUHU01000002_gene2481 1.77e-27 102.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,468RS@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspD GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_10169_2 391625.PPSIR1_38636 0.000557 45.8 COG1716@1|root,COG2197@1|root,COG1716@2|Bacteria,COG2197@2|Bacteria,1NK4J@1224|Proteobacteria 1224|Proteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_16431_1 231434.JQJH01000001_gene1833 1.52e-64 218.0 COG0607@1|root,COG0778@1|root,COG0607@2|Bacteria,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,2U1WC@28211|Alphaproteobacteria,3NA2S@45404|Beijerinckiaceae 28211|Alphaproteobacteria CP Nitroreductase family - - - - - - - - - - - - Nitroreductase,Rhodanese k141_15800_1 985054.JQEZ01000003_gene1214 1.9e-109 327.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4NAED@97050|Ruegeria 28211|Alphaproteobacteria Q Trap dicarboxylate transporter, dctm subunit - - - - - - - - - - - - DctM k141_3882_1 384765.SIAM614_17164 1.04e-126 374.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM k141_3882_2 1123247.AUIJ01000001_gene1730 4.38e-84 269.0 COG4665@1|root,COG4665@2|Bacteria,1QZG7@1224|Proteobacteria,2U0WE@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_3882_3 1123247.AUIJ01000001_gene1731 7.65e-128 372.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_5319_1 1328313.DS2_16159 3.22e-61 190.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,4678S@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_5319_2 1348114.OM33_02315 3.08e-39 147.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,2Q0SJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt k141_5982_1 545264.KB898749_gene89 5.7e-104 317.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_19299_2 1122194.AUHU01000005_gene938 1.37e-20 87.4 COG1716@1|root,COG1716@2|Bacteria,1PEEJ@1224|Proteobacteria,1S9J0@1236|Gammaproteobacteria,468T1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_19299_3 247634.GPB2148_723 4.81e-259 730.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1J4FT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_15047_1 1042375.AFPL01000046_gene1850 7.19e-101 315.0 COG0404@1|root,COG3665@1|root,COG0404@2|Bacteria,COG3665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C k141_15047_2 1395571.TMS3_0107250 5.81e-174 496.0 COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,1RPVS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium transporter - - - - - - - - - - - - Ammonium_transp k141_17131_2 1123399.AQVE01000017_gene3623 1.27e-24 96.3 COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1SEE6@1236|Gammaproteobacteria,4636A@72273|Thiotrichales 72273|Thiotrichales P Rieske-like [2Fe-2S] domain - - - ko:K14750 ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220 - R05440 RC00098 br01602,ko00000,ko00001 - - - Rieske k141_17131_4 1163617.SCD_n02060 4.89e-125 381.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria 1224|Proteobacteria C oxidoreductase FAD NAD(P)-binding domain protein - - - - - - - - - - - - FAD_binding_6,Fer2 k141_17131_5 1026882.MAMP_02122 1.51e-43 143.0 2CDMX@1|root,32S1K@2|Bacteria,1N1I8@1224|Proteobacteria,1S9N4@1236|Gammaproteobacteria,4630G@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_7396_1 1278309.KB907105_gene1407 1.59e-78 240.0 2EDFM@1|root,337BV@2|Bacteria,1NAR8@1224|Proteobacteria,1SE73@1236|Gammaproteobacteria,1XM3B@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7396_2 1278309.KB907105_gene1408 4.05e-94 286.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1XJ8D@135619|Oceanospirillales 135619|Oceanospirillales S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_10917_1 1278309.KB907100_gene2141 5.2e-20 89.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNG1@1236|Gammaproteobacteria,1XR30@135619|Oceanospirillales 135619|Oceanospirillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_10917_2 1278309.KB907100_gene2142 3.57e-131 376.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,1XJV7@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_10917_3 1278309.KB907100_gene2143 1.64e-50 166.0 COG3678@1|root,COG3678@2|Bacteria,1QTNS@1224|Proteobacteria,1RXSJ@1236|Gammaproteobacteria,1XMVX@135619|Oceanospirillales 135619|Oceanospirillales NPTU LTXXQ motif family protein - - - - - - - - - - - - LTXXQ k141_10917_4 1278309.KB907100_gene2144 2.21e-64 204.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,1XM11@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 k141_12317_1 697282.Mettu_2756 6.7e-65 210.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,1T3H9@1236|Gammaproteobacteria,1XDWD@135618|Methylococcales 135618|Methylococcales H Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_1154_1 1198232.CYCME_0386 5.4e-270 754.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,4607G@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_10170_1 713586.KB900536_gene1719 3.47e-58 184.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_10170_2 1388763.O165_025200 7.08e-38 134.0 COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,1T1GC@1236|Gammaproteobacteria,1YVD1@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_13010_1 314278.NB231_01154 1.43e-52 177.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales 135613|Chromatiales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_13010_2 187272.Mlg_1350 1.93e-114 335.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales 135613|Chromatiales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_1832_1 1056820.KB900664_gene3678 1.21e-23 99.4 COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,1RYEE@1236|Gammaproteobacteria,2PNKR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria V Restriction endonuclease mrr GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 - ko:K07448 - - - - ko00000,ko02048 - - - HARE-HTH,Mrr_N,Mrr_cat k141_4638_1 391615.ABSJ01000055_gene1322 2.13e-101 306.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1J9QP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Aminotransferase class I and II hisC GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - iECO111_1330.ECO111_2745,iSDY_1059.SDY_2220,iSSON_1240.SSON_2092 Aminotran_1_2 k141_13693_1 207954.MED92_06776 1.64e-105 318.0 COG0546@1|root,COG1040@1|root,COG0546@2|Bacteria,COG1040@2|Bacteria,1R73Z@1224|Proteobacteria,1SKI8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoglycolate phosphatase activity - - - - - - - - - - - - - k141_6655_1 1123514.KB905899_gene842 3.12e-102 320.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_15802_2 2340.JV46_07200 1.17e-51 168.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1J5S0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_7397_1 1276257.SSABA_v1c01810 1.67e-10 62.0 COG0350@1|root,COG0350@2|Bacteria,3WU43@544448|Tenericutes 544448|Tenericutes L 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567,ko:K13531 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 k141_22039_1 518766.Rmar_2413 8.75e-05 48.1 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1FIZ3@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA k141_22039_2 519989.ECTPHS_02526 1.67e-99 301.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_3883_1 1278309.KB907101_gene395 1.01e-122 360.0 28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1XHY9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_3883_2 1278309.KB907101_gene394 3.94e-11 61.6 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_2503_2 717772.THIAE_07010 2.32e-124 362.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RVP9@1236|Gammaproteobacteria,461M0@72273|Thiotrichales 72273|Thiotrichales P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_2503_3 1269813.ATUL01000011_gene591 7.49e-87 275.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales 135613|Chromatiales KT Fis Family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat k141_14326_1 1123237.Salmuc_01244 2.95e-11 64.3 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2U95K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF498/DUF598) MA20_41450 - - - - - - - - - - - DUF498 k141_11575_1 1278309.KB907100_gene1887 1.33e-174 506.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales 135619|Oceanospirillales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_11575_2 1278309.KB907100_gene1888 8.78e-268 744.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1XHCG@135619|Oceanospirillales 135619|Oceanospirillales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_446_1 391615.ABSJ01000039_gene1855 8.8e-29 114.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1J5VI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_446_2 1122134.KB893650_gene344 0.0 1152.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1XHZE@135619|Oceanospirillales 135619|Oceanospirillales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_446_3 396588.Tgr7_0210 5.76e-208 587.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1X0FA@135613|Chromatiales 135613|Chromatiales P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_446_5 765910.MARPU_02205 2.49e-201 562.0 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1WXJM@135613|Chromatiales 135613|Chromatiales G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_16432_1 391612.CY0110_25486 1.75e-15 85.9 COG0642@1|root,COG2202@1|root,COG3899@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GD97@1117|Cyanobacteria,3KHHW@43988|Cyanothece 1117|Cyanobacteria T Serine Threonine protein kinase - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,PAS_9,Response_reg k141_16432_2 1297581.H919_09938 3.2e-08 52.4 2AEQG@1|root,314M1@2|Bacteria,1VQFC@1239|Firmicutes,4HRE0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_15048_1 343509.SG1845 1.64e-36 133.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the DegT DnrJ EryC1 family arnB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 ko:K07806 ko00520,ko01503,ko02020,map00520,map01503,map02020 M00721,M00761 R07659 RC00006,RC01514 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 - - iSFxv_1172.SFxv_2574 DegT_DnrJ_EryC1 k141_5320_2 243233.MCA0853 3.78e-58 202.0 COG0714@1|root,COG1067@1|root,COG0714@2|Bacteria,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XEPA@135618|Methylococcales 135618|Methylococcales O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_18528_1 1278309.KB907101_gene579 4.09e-222 624.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XHB9@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_18528_2 1278309.KB907101_gene580 1.63e-207 588.0 28H91@1|root,2Z7KU@2|Bacteria,1R4NB@1224|Proteobacteria,1S6NY@1236|Gammaproteobacteria,1XKBX@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10172_1 864069.MicloDRAFT_00024070 4.23e-30 115.0 COG1802@1|root,COG1802@2|Bacteria,1R90Y@1224|Proteobacteria,2U6A9@28211|Alphaproteobacteria,1JR4S@119045|Methylobacteriaceae 28211|Alphaproteobacteria K PFAM regulatory protein GntR HTH matR - - - - - - - - - - - FCD,GntR k141_10919_1 1411685.U062_02362 2.54e-17 77.4 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1J75G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15803_1 390235.PputW619_3655 2.06e-30 110.0 COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,1SCWV@1236|Gammaproteobacteria,1YVJX@136845|Pseudomonas putida group 1236|Gammaproteobacteria S FlhB HrpN YscU SpaS Family flhB2 - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 k141_3258_1 398578.Daci_5314 4.09e-33 133.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2VPBJ@28216|Betaproteobacteria,4AD55@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM Rhomboid family protein - - - - - - - - - - - - Rhomboid k141_3258_2 398579.Spea_3010 1.47e-22 101.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,2Q8PX@267890|Shewanellaceae 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_21378_2 870187.Thini_1248 9.55e-68 226.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales 72273|Thiotrichales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family napA - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_13011_1 870187.Thini_1080 2.16e-39 137.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_3884_1 744979.R2A130_3263 6.31e-82 259.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family MA20_27780 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_13695_1 1278309.KB907100_gene2205 5.16e-66 207.0 COG5285@1|root,COG5285@2|Bacteria,1PF68@1224|Proteobacteria,1RYF8@1236|Gammaproteobacteria,1XPMF@135619|Oceanospirillales 135619|Oceanospirillales Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH k141_17886_1 1177179.A11A3_14712 9.59e-24 100.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RNIM@1236|Gammaproteobacteria,1XQZY@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Osmo_CC,Sugar_tr k141_11576_1 697282.Mettu_1903 9.27e-87 276.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XE7K@135618|Methylococcales 135618|Methylococcales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_5984_1 1288826.MSNKSG1_14717 1.04e-242 684.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_2505_2 7213.XP_004528068.1 2.92e-15 76.6 COG0539@1|root,KOG1070@2759|Eukaryota,39N76@33154|Opisthokonta,3CPSG@33208|Metazoa,3DE11@33213|Bilateria,422RV@6656|Arthropoda,3SQVP@50557|Insecta 33208|Metazoa A S1 RNA binding domain - - - - - - - - - - - - S1 k141_7525_16 1288826.MSNKSG1_12297 3.4e-208 578.0 COG3016@1|root,COG3016@2|Bacteria,1RAAM@1224|Proteobacteria,1T1A0@1236|Gammaproteobacteria,46AY6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haem-binding uptake, Tiki superfamily, ChaN - - - - - - - - - - - - Cofac_haem_bdg k141_7525_17 1288826.MSNKSG1_12292 3.72e-35 119.0 COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,1SCP8@1236|Gammaproteobacteria,468ND@72275|Alteromonadaceae 1236|Gammaproteobacteria K copG family - - - - - - - - - - - - - k141_7525_18 1288826.MSNKSG1_12287 0.0 1069.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4650I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) ychM GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - iSbBS512_1146.SbBS512_E1370 STAS,Sulfate_transp k141_7525_19 1288826.MSNKSG1_12282 0.0 1060.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,4659E@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_7525_20 1288826.MSNKSG1_12262 2.28e-45 162.0 2DBVZ@1|root,2ZBDU@2|Bacteria,1R8P2@1224|Proteobacteria,1TIDG@1236|Gammaproteobacteria,469RI@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7525_21 1288826.MSNKSG1_12257 3.75e-64 197.0 2EGYY@1|root,33AR2@2|Bacteria,1NGMM@1224|Proteobacteria,1SJCX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7525_22 1288826.MSNKSG1_12252 1.84e-152 428.0 COG3271@1|root,COG3271@2|Bacteria,1RHAJ@1224|Proteobacteria,1S6IC@1236|Gammaproteobacteria,467G3@72275|Alteromonadaceae 1236|Gammaproteobacteria S peptidase C39, bacteriocin processing - - - ko:K06992 - - - - ko00000 - - - Peptidase_C39 k141_7525_23 1288826.MSNKSG1_12247 4.18e-109 318.0 2CGFE@1|root,32S3V@2|Bacteria,1N6JI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_22166_1 479432.Sros_7602 1.26e-08 56.6 COG0789@1|root,COG0789@2|Bacteria,2IFX0@201174|Actinobacteria,4EJH1@85012|Streptosporangiales 201174|Actinobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 k141_22166_2 264198.Reut_A2830 7.53e-13 64.7 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,1K6Z5@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM conserved - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_21505_1 395493.BegalDRAFT_0809 1.21e-67 224.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,45ZS9@72273|Thiotrichales 72273|Thiotrichales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_16558_1 1121904.ARBP01000019_gene2773 5.18e-94 290.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_11038_1 519989.ECTPHS_06682 4.55e-35 130.0 COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S5D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L nuclease - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - DUF4124,SNase k141_11038_2 1112274.KI911560_gene2650 4.39e-65 210.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KMFE@206350|Nitrosomonadales 206350|Nitrosomonadales C PFAM malic protein NAD-binding - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_12465_1 472759.Nhal_2808 1.23e-65 211.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales 135613|Chromatiales S Methyltransferase - - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 k141_8277_1 1163617.SCD_n01162 3.23e-119 354.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria 28216|Betaproteobacteria P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_19392_1 397287.C807_01416 3.06e-41 150.0 COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia,27IP1@186928|unclassified Lachnospiraceae 186801|Clostridia NT Methyltransferase, chemotaxis proteins cheR - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_19392_3 1173027.Mic7113_5459 4.79e-43 153.0 COG0615@1|root,COG0615@2|Bacteria,1G4EC@1117|Cyanobacteria,1HA3B@1150|Oscillatoriales 1117|Cyanobacteria IM PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_3 k141_2618_2 715226.ABI_20080 3.21e-08 57.8 COG4421@1|root,COG4421@2|Bacteria,1NH8W@1224|Proteobacteria,2UKSD@28211|Alphaproteobacteria,2KJEQ@204458|Caulobacterales 204458|Caulobacterales G Protein of unknown function (DUF563) - - - - - - - - - - - - DUF563 k141_1290_1 1234364.AMSF01000060_gene962 3.25e-85 252.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1X61V@135614|Xanthomonadales 135614|Xanthomonadales J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_1290_2 1234364.AMSF01000060_gene961 4.23e-18 77.8 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1X64V@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_6098_1 1278309.KB907101_gene719 4.1e-112 333.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1XHKR@135619|Oceanospirillales 135619|Oceanospirillales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_9539_1 1149133.ppKF707_5410 7.54e-16 75.1 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1YJAG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_9539_2 1042375.AFPL01000008_gene3243 6.33e-28 109.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,468IU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_13146_1 768066.HELO_3823 1.89e-35 129.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XH8W@135619|Oceanospirillales 135619|Oceanospirillales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_13146_2 396588.Tgr7_0300 5.51e-138 410.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_18686_1 1149133.ppKF707_6196 1.13e-98 307.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K11914,ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko02044,ko03000 - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_16559_1 357804.Ping_3157 4.71e-101 311.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K13896,ko:K19229,ko:K19230 ko01503,ko02010,ko02024,map01503,map02010,map02024 M00239,M00349,M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24,3.A.1.5.5 - - ABC_tran,oligo_HPY k141_22168_1 765913.ThidrDRAFT_3394 3.29e-90 281.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_15911_1 1278309.KB907102_gene5 3.23e-127 368.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1XIBG@135619|Oceanospirillales 135619|Oceanospirillales M Polysaccharide biosynthesis protein - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_8278_1 1049564.TevJSym_bk00210 9.31e-81 251.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J4SA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_5467_1 765910.MARPU_04090 3.72e-29 108.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales 135613|Chromatiales T low molecular weight - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_5467_2 582744.Msip34_0615 1.04e-45 153.0 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KMQH@206350|Nitrosomonadales 206350|Nitrosomonadales F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ - - - - - - - - - - - NUDIX k141_5467_3 765913.ThidrDRAFT_0316 9.88e-24 99.4 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1WVZU@135613|Chromatiales 135613|Chromatiales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_8859_1 227377.CBU_0473 1.28e-30 111.0 COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the bacterial histone-like protein family VL23_14575 - - - - - - - - - - - Bac_DNA_binding k141_8859_2 351160.RCIX925 1.38e-05 49.3 COG1011@1|root,arCOG02291@2157|Archaea 2157|Archaea S hydrolase (HAD superfamily) - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_20736_1 1123360.thalar_00209 2.97e-06 47.8 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_20736_2 1089551.KE386572_gene3366 1.12e-40 139.0 COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,4BQE0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K ROS/MUCR transcriptional regulator protein mucR - - - - - - - - - - - ROS_MUCR k141_1291_1 1212548.B381_08876 2.78e-09 64.3 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1Z27R@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_14428_1 1288826.MSNKSG1_00021 2.78e-111 320.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,468GJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_14428_2 1288826.MSNKSG1_00016 1.09e-162 458.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1S6T6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14428_3 1288826.MSNKSG1_00011 6.27e-13 67.4 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,464RE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0066 HMGL-like,LeuA_dimer k141_21507_1 1042375.AFPL01000004_gene626 1.89e-14 78.2 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317 HemX k141_1298_8 1288826.MSNKSG1_09468 0.0 874.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465BW@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4,6.4.1.5 ko:K01968,ko:K13777 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R03494,R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_6113_1 1288826.MSNKSG1_15452 0.0 939.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,469S2@72275|Alteromonadaceae 1236|Gammaproteobacteria C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region fdhF GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 ko:K00123,ko:K22015 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - iECBD_1354.ECBD_3953 Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_6113_2 1288826.MSNKSG1_15447 0.0 934.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,46546@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB k141_9558_1 301.JNHE01000026_gene3109 1.64e-24 107.0 COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE8V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3 k141_6769_1 768671.ThimaDRAFT_3035 2.23e-19 89.4 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WX7A@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_6769_2 1168067.JAGP01000001_gene364 8.13e-114 335.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,45ZZM@72273|Thiotrichales 72273|Thiotrichales H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_17278_1 754477.Q7C_1738 4.8e-109 346.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,45ZPD@72273|Thiotrichales 72273|Thiotrichales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_22185_1 1026882.MAMP_01569 1.03e-124 380.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein Ccs1 ResB - - - ko:K07399 - - - - ko00000 - - - ResB k141_22185_2 1166948.JPZL01000003_gene503 1.1e-50 167.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_7540_1 2340.JV46_23630 1.26e-153 440.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1J54M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_5478_1 1123514.KB905899_gene842 1.85e-105 328.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_3378_1 1278309.KB907101_gene337 2.75e-234 648.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XI6J@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_8869_1 1278309.KB907106_gene1291 2.24e-67 216.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1XHSG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the peptidase M24B family pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_8869_2 1278309.KB907106_gene1292 7.23e-257 710.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1XHQ8@135619|Oceanospirillales 135619|Oceanospirillales CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_8869_3 1278309.KB907106_gene1293 2.02e-15 75.1 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales 135619|Oceanospirillales CH hydroxylase ubiF - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_8292_2 1121012.AUKX01000011_gene2328 8.73e-10 58.9 COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia,23GT1@178469|Arenibacter 976|Bacteroidetes S Carbon-nitrogen hydrolase ramA_2 - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_13843_1 697282.Mettu_3160 1.89e-54 194.0 COG2202@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,GAF_2,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Hpt,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Phosphonate-bd,Reg_prop,Response_reg,TarH,Y_Y_Y k141_11703_1 998674.ATTE01000001_gene3034 4.28e-67 205.0 COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,1S654@1236|Gammaproteobacteria,463ES@72273|Thiotrichales 72273|Thiotrichales S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL_2 k141_2636_2 1117318.PRUB_12876 7.06e-53 174.0 COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,1S6W5@1236|Gammaproteobacteria,2Q3JU@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_N k141_20021_1 351348.Maqu_2182 6.14e-24 106.0 COG5001@1|root,COG5001@2|Bacteria,1QR8J@1224|Proteobacteria,1RZA7@1236|Gammaproteobacteria,4655P@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,dCache_1 k141_12483_1 1278309.KB907107_gene1745 9.74e-53 176.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XIS3@135619|Oceanospirillales 135619|Oceanospirillales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_12483_2 1278309.KB907107_gene1746 1.46e-137 391.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1XIV2@135619|Oceanospirillales 135619|Oceanospirillales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_12483_3 95619.PM1_0209020 4.06e-17 78.6 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_15935_2 666685.R2APBS1_1117 2.99e-70 222.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S5DB@1236|Gammaproteobacteria,1X4XD@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF502) YH67_14670 - - - - - - - - - - - DUF502 k141_15935_3 264198.Reut_A2497 0.000347 43.1 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1K4AM@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_6770_1 338969.Rfer_2356 8.78e-20 94.7 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4AJWE@80864|Comamonadaceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg k141_4784_1 1121004.ATVC01000032_gene2193 3.4e-25 114.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VRWJ@28216|Betaproteobacteria,2KR1V@206351|Neisseriales 206351|Neisseriales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_22186_1 870187.Thini_4246 5.31e-84 270.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3 k141_3379_1 1122137.AQXF01000001_gene2639 5.97e-37 143.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria 28211|Alphaproteobacteria T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,PilZ,dCache_1 k141_6114_1 1049564.TevJSym_bc00140 7.48e-115 339.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1J5AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k141_6114_2 2340.JV46_14790 1.09e-72 227.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1J5D9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360 ACP_syn_III,ACP_syn_III_C k141_18052_2 247633.GP2143_13401 1.9e-11 60.1 COG3242@1|root,COG3242@2|Bacteria,1N9FC@1224|Proteobacteria,1SEP6@1236|Gammaproteobacteria,1J79M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2065) - - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_8293_1 2340.JV46_22500 1.53e-105 310.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_14438_1 1288826.MSNKSG1_03141 3.29e-160 449.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,466FV@72275|Alteromonadaceae 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_14438_2 1288826.MSNKSG1_03136 8.42e-156 445.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,465R6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 LpxB k141_4127_1 1449065.JMLL01000010_gene266 1.7e-74 233.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,43IDK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Cytochrome c cycG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C k141_6938_1 1026882.MAMP_00291 8.05e-67 206.0 2E1WQ@1|root,32X5W@2|Bacteria,1N2F8@1224|Proteobacteria,1SA2N@1236|Gammaproteobacteria,462KZ@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_15305_1 697282.Mettu_1061 2.56e-111 361.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_15305_2 472759.Nhal_0252 4.39e-23 98.6 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1WXQX@135613|Chromatiales 135613|Chromatiales L DNA photolyase - - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_11835_1 290400.Jann_0919 9.84e-70 231.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family dmgdh2 - 1.5.8.4 ko:K00315 ko00260,ko01100,map00260,map01100 - R01565 RC00181 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C k141_11835_3 195105.CN97_01130 2.81e-65 220.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0339 Zn-dependent oligopeptidases dcp GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_6939_2 768671.ThimaDRAFT_2669 2.09e-23 93.2 COG0790@1|root,COG0790@2|Bacteria,1N293@1224|Proteobacteria,1SBGP@1236|Gammaproteobacteria,1WYX5@135613|Chromatiales 135613|Chromatiales S Sel1-like repeats. - - - - - - - - - - - - Sel1 k141_4128_1 1049564.TevJSym_bd00260 1.16e-136 399.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1J7KN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cysteine-rich domain glpC GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 ko:K00113,ko:K11473 ko00564,ko00630,ko01100,ko01110,ko01120,ko01130,map00564,map00630,map01100,map01110,map01120,map01130 - R00475,R00848 RC00029,RC00042 ko00000,ko00001,ko01000 - - - CCG,Fer4_8 k141_20158_2 472759.Nhal_1250 3.82e-102 304.0 COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,1S31N@1236|Gammaproteobacteria,1WXP2@135613|Chromatiales 135613|Chromatiales G PFAM Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_6940_1 1124780.ANNU01000015_gene1984 1.37e-10 63.9 COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - DUF4175 k141_6940_2 929704.Myrod_1614 7.51e-32 118.0 COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia,47HR8@76831|Myroides 976|Bacteroidetes L Endonuclease/Exonuclease/phosphatase family xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_6941_1 1168067.JAGP01000001_gene1365 1.54e-43 161.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales 72273|Thiotrichales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_11836_2 1123296.JQKE01000021_gene980 4.95e-119 343.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KPI7@206351|Neisseriales 206351|Neisseriales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_4129_1 395493.BegalDRAFT_0242 3.49e-102 326.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales 72273|Thiotrichales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_15307_1 1237149.C900_04466 1.17e-24 100.0 COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia 976|Bacteroidetes G PFAM Starch synthase catalytic domain glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5 k141_6942_1 1278309.KB907102_gene124 1.14e-136 407.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XHDT@135619|Oceanospirillales 135619|Oceanospirillales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_9740_1 1210884.HG799462_gene8001 2.14e-09 58.5 COG0653@1|root,COG0653@2|Bacteria,2IXIT@203682|Planctomycetes 203682|Planctomycetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_9740_2 187272.Mlg_2085 6.94e-74 234.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1WWSU@135613|Chromatiales 135613|Chromatiales E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_11837_1 929562.Emtol_4245 3.02e-13 66.6 COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,47MHB@768503|Cytophagia 976|Bacteroidetes Q PFAM fumarylacetoacetate (FAA) hydrolase fahA - - - - - - - - - - - FAA_hydrolase k141_11837_2 1121373.KB903654_gene1508 9.54e-37 133.0 COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,47JGC@768503|Cytophagia 976|Bacteroidetes O PFAM Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_4130_1 1288826.MSNKSG1_10488 1.05e-119 345.0 COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,1S4NN@1236|Gammaproteobacteria,46CHB@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_15309_1 1305737.JAFX01000001_gene2956 1.3e-25 104.0 COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,47MKU@768503|Cytophagia 976|Bacteroidetes M Transglycosylase SLT domain mltD_2 - - - - - - - - - - - SLT k141_15309_2 313606.M23134_05873 7.22e-08 55.5 COG0637@1|root,COG0637@2|Bacteria,4NPDJ@976|Bacteroidetes 976|Bacteroidetes S HAD-superfamily hydrolase subfamily IA, variant 3 - - - - - - - - - - - - HAD_2 k141_20160_1 1313421.JHBV01000030_gene2180 3.12e-13 68.2 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia 976|Bacteroidetes G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK k141_20160_2 1237149.C900_04814 1.46e-23 99.8 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 k141_4131_1 1158760.AQXP01000053_gene1481 6.41e-82 255.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RM8C@1236|Gammaproteobacteria,1WWUM@135613|Chromatiales 135613|Chromatiales E PFAM Orn DAP Arg decarboxylase 2 - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_11840_1 1122619.KB892295_gene2039 1.75e-05 50.4 COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VSZY@28216|Betaproteobacteria,3T3K6@506|Alcaligenaceae 28216|Betaproteobacteria S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET k141_9742_1 1150469.RSPPHO_01558 9.26e-65 210.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,2JR9I@204441|Rhodospirillales 204441|Rhodospirillales KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_20161_1 1094715.CM001373_gene825 5.35e-81 249.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,1JDG6@118969|Legionellales 118969|Legionellales S Glucose-regulated metallo-peptidase M90 mtfA - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_15310_1 243159.AFE_2861 4.08e-43 156.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,2NCFN@225057|Acidithiobacillales 225057|Acidithiobacillales M Secretion protein, HlyD - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 k141_4132_1 367336.OM2255_10795 9.16e-96 286.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family vdlC GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - - - - - - - - - - adh_short k141_11841_1 1188256.BASI01000001_gene409 2.35e-44 145.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2U70K@28211|Alphaproteobacteria,3FD2N@34008|Rhodovulum 28211|Alphaproteobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_20162_1 1123517.JOMR01000001_gene558 2.42e-75 251.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg k141_9743_1 382245.ASA_4382 7.45e-08 57.8 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1Y3NC@135624|Aeromonadales 135624|Aeromonadales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_9743_2 1305836.AXVE01000003_gene2174 9.49e-21 85.1 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,26G45@186818|Planococcaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic k141_15311_2 1116472.MGMO_44c00380 5.98e-50 164.0 COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1S271@1236|Gammaproteobacteria,1XEEV@135618|Methylococcales 135618|Methylococcales S small GTP-binding protein - - - ko:K06945 - - - - ko00000 - - - ATP_bind_1 k141_11843_1 1288826.MSNKSG1_17621 5.95e-45 149.0 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,46885@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_11843_2 1288826.MSNKSG1_17626 2.63e-73 220.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,4677W@72275|Alteromonadaceae 1236|Gammaproteobacteria C Iron-sulfur cluster insertion protein ErpA erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564 - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_11843_3 1288826.MSNKSG1_17631 9.15e-157 445.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,464CU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK k141_9746_1 85643.Tmz1t_1723 5.19e-75 236.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,2KUQE@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_6943_1 1278309.KB907100_gene2261 0.0 1164.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XH31@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_6943_2 1278309.KB907100_gene2262 8.28e-168 472.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XHB7@135619|Oceanospirillales 135619|Oceanospirillales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_6943_3 1278309.KB907100_gene2263 1.12e-215 595.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales 135619|Oceanospirillales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_6943_4 1278309.KB907100_gene2264 3.92e-106 308.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1XK4A@135619|Oceanospirillales 135619|Oceanospirillales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_6943_5 1278309.KB907100_gene2265 1.5e-07 50.8 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XJV4@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) - - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_9747_1 1449350.OCH239_14585 1.23e-59 201.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,4KK9Z@93682|Roseivivax 28211|Alphaproteobacteria U Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_6944_1 1200792.AKYF01000009_gene2953 3.91e-51 174.0 28K7U@1|root,2Z9VT@2|Bacteria,1VAFZ@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_6944_2 891974.E05_50830 0.000729 40.8 2ENIZ@1|root,33G6D@2|Bacteria,1NIBA@1224|Proteobacteria,1SGTT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20165_3 469381.Dpep_1976 5.82e-22 91.7 COG0727@1|root,COG0727@2|Bacteria,3TBB7@508458|Synergistetes 508458|Synergistetes S PFAM Uncharacterised protein family (UPF0153) - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_9748_1 999611.KI421504_gene788 7.04e-44 157.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,27ZM8@191028|Leisingera 28211|Alphaproteobacteria H Elongator protein 3, MiaB family, Radical SAM hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_6945_1 187272.Mlg_0377 6.22e-52 176.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_11844_1 1232683.ADIMK_4142 9.1e-21 88.6 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,46C5D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase mhpB - - - - - - - - - - - LigB k141_11844_2 1232683.ADIMK_4143 5.3e-73 221.0 COG3384@1|root,COG3384@2|Bacteria,1RIBC@1224|Proteobacteria,1SYBG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA k141_11844_3 1278309.KB907101_gene340 3.38e-133 387.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1RZI8@1236|Gammaproteobacteria,1XJHX@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, arabinose operon control protein - - - ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 k141_4135_1 443143.GM18_2098 6.01e-81 281.0 COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - HATPase_c,HisKA,Response_reg,dCache_1 k141_15314_1 1236959.BAMT01000003_gene536 2.34e-11 63.9 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,2KNJR@206350|Nitrosomonadales 206350|Nitrosomonadales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_6946_1 396588.Tgr7_3079 1.08e-104 313.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_9749_1 1123392.AQWL01000002_gene1843 1.63e-20 84.0 2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_6947_1 301.JNHE01000013_gene2791 2.3e-132 391.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1YE4T@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_11845_1 187272.Mlg_0338 2.67e-28 111.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1WYIB@135613|Chromatiales 135613|Chromatiales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metXS - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_11845_2 522306.CAP2UW1_2729 1.14e-80 268.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria 28216|Betaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_6948_1 1298593.TOL_2415 6.7e-51 171.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,1XIZT@135619|Oceanospirillales 135619|Oceanospirillales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_15315_1 1278309.KB907100_gene1808 4.1e-281 799.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XI0M@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_11846_1 472759.Nhal_1513 1.64e-43 149.0 COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales 135613|Chromatiales V (ABC) transporter - - - - - - - - - - - - - k141_9752_1 1278309.KB907099_gene2754 2.24e-98 286.0 COG2371@1|root,COG2371@2|Bacteria,1RFX7@1224|Proteobacteria,1S57N@1236|Gammaproteobacteria,1XREK@135619|Oceanospirillales 135619|Oceanospirillales O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly ureE - - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N k141_9752_2 1042375.AFPL01000010_gene452 3.28e-22 91.7 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,467BB@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_10561_2 1123400.KB904802_gene3183 1.1e-147 423.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,460DH@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N k141_14758_2 80884.CCF37043 1.93e-05 45.4 COG0099@1|root,KOG3311@2759|Eukaryota,3A3EC@33154|Opisthokonta,3P3ZS@4751|Fungi,3QWRM@4890|Ascomycota,21ASA@147550|Sordariomycetes,1F323@1028384|Glomerellales 4751|Fungi J Belongs to the universal ribosomal protein uS13 family - GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0071840,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_15475_1 1209072.ALBT01000023_gene3948 5.14e-25 102.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1FG4X@10|Cellvibrio 1236|Gammaproteobacteria H Quinolinate phosphoribosyl transferase, N-terminal domain nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_21067_1 909663.KI867149_gene3250 3.4e-14 77.8 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,42X97@68525|delta/epsilon subdivisions,2WNMY@28221|Deltaproteobacteria 28221|Deltaproteobacteria KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k141_74_1 1249627.D779_0264 4.74e-130 380.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1WWRP@135613|Chromatiales 135613|Chromatiales C Isocitrate lyase - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_74_2 998674.ATTE01000001_gene3819 6.15e-53 176.0 COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,1S88Y@1236|Gammaproteobacteria,462IW@72273|Thiotrichales 72273|Thiotrichales S amidohydrolase - - - - - - - - - - - - - k141_5710_1 1121123.AUAO01000005_gene1750 6.64e-09 60.1 COG3369@1|root,COG3369@2|Bacteria,1RCN9@1224|Proteobacteria,2U878@28211|Alphaproteobacteria,2KHJ4@204458|Caulobacterales 204458|Caulobacterales S CDGSH-type zinc finger. Function unknown. - - - - - - - - - - - - Fer4_19,Ferritin-like,zf-CDGSH k141_5710_2 261292.Nit79A3_3404 2.38e-67 210.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity gpmB - - - - - - - - - - - His_Phos_1 k141_5710_3 582744.Msip34_2228 6.77e-17 80.1 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,2KNEN@206350|Nitrosomonadales 206350|Nitrosomonadales S Cobalt uptake substrate-specific transmembrane region - - - - - - - - - - - - CbiM k141_14759_2 1121127.JAFA01000023_gene7217 1.05e-21 95.9 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,1K15K@119060|Burkholderiaceae 28216|Betaproteobacteria F Belongs to the dGTPase family. Type 2 subfamily dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_7066_1 485913.Krac_7657 1.61e-70 231.0 COG0477@1|root,COG0477@2|Bacteria,2GA6R@200795|Chloroflexi 200795|Chloroflexi EGP Major facilitator superfamily - - - - - - - - - - - - MFS_3 k141_7066_2 1123368.AUIS01000032_gene1394 1.18e-17 84.0 COG1080@1|root,COG1080@2|Bacteria 2|Bacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_19613_1 1267535.KB906767_gene5091 6.65e-12 68.6 COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia 57723|Acidobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran k141_19613_2 1283300.ATXB01000001_gene1784 3.16e-26 104.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1XDJA@135618|Methylococcales 135618|Methylococcales S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_8468_1 1278309.KB907099_gene2853 2.37e-62 211.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XIC7@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_8468_2 1278309.KB907099_gene2852 6.82e-61 188.0 COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,1S9F1@1236|Gammaproteobacteria,1XKM1@135619|Oceanospirillales 135619|Oceanospirillales P Nitrite reductase nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske_2 k141_8468_3 1278309.KB907099_gene2851 1.53e-94 300.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XI8D@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_15476_1 1163408.UU9_09472 3.57e-28 104.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1X7JD@135614|Xanthomonadales 135614|Xanthomonadales KL Belongs to the transcriptional regulatory Fis family fis GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_10562_1 396588.Tgr7_1912 5.65e-104 310.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_11292_1 292415.Tbd_0889 4.2e-27 111.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria 28216|Betaproteobacteria S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_6367_1 314345.SPV1_00095 1.48e-115 367.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_17505_1 686340.Metal_0421 3.48e-61 206.0 COG0811@1|root,COG5306@1|root,COG0811@2|Bacteria,COG5306@2|Bacteria,1N2RJ@1224|Proteobacteria,1RMZK@1236|Gammaproteobacteria,1XEJS@135618|Methylococcales 135618|Methylococcales U MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB k141_14760_2 404589.Anae109_3714 5.91e-40 134.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales 28221|Deltaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_20350_1 1461693.ATO10_13644 3.35e-85 261.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Cysteine synthase cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_20350_2 290400.Jann_2781 4.49e-07 50.8 COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_5711_1 204669.Acid345_3443 3.76e-17 84.3 COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia 204432|Acidobacteriia S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_21676_2 1304888.ATWF01000001_gene1019 8.69e-25 102.0 COG4663@1|root,COG4663@2|Bacteria,2GFC6@200930|Deferribacteres 200930|Deferribacteres C C4-dicarboxylate transporter, substrate-binding protein - - - - - - - - - - - - DctP k141_7067_1 1283079.M1ID95_9CAUD 2.55e-34 137.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k141_7791_1 1288826.MSNKSG1_08928 1.23e-135 391.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,464WH@72275|Alteromonadaceae 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_7791_2 1288826.MSNKSG1_08923 2.13e-137 397.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_6368_1 1198232.CYCME_1169 4.7e-98 298.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,46007@72273|Thiotrichales 72273|Thiotrichales S DNA recombination protein RmuC - - - ko:K09760 - - - - ko00000 - - - RmuC k141_4960_1 1278309.KB907103_gene1022 0.0 1271.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XHMF@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_4960_2 1278309.KB907103_gene1021 6.32e-28 103.0 2EF5A@1|root,338YG@2|Bacteria,1NAMT@1224|Proteobacteria,1SFS9@1236|Gammaproteobacteria,1XMIU@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10563_1 1195246.AGRI_15590 2.48e-85 258.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,464N4@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_17506_2 543728.Vapar_5340 8.36e-12 64.7 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,4AA73@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_3598_2 187272.Mlg_1093 1.7e-93 283.0 COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,1S29T@1236|Gammaproteobacteria,1X0GP@135613|Chromatiales 135613|Chromatiales V TIGRFAM ABC-2 type transporter, NodJ - - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane k141_8469_1 1158165.KB898872_gene1094 2.8e-175 513.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.1,1.7.1.15 ko:K00362,ko:K05297 ko00071,ko00910,ko01120,map00071,map00910,map01120 M00530 R00787,R02000 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_11964_1 1337093.MBE-LCI_3314 1.31e-74 239.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_14761_1 1049564.TevJSym_an00780 9.35e-112 338.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1J4QJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_9846_1 207954.MED92_17948 1.43e-51 173.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XH38@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_9846_2 1278309.KB907100_gene1993 3.63e-95 280.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1XJIB@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_10585_1 266809.PM03_05105 1.49e-89 280.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_10585_2 745014.OMB55_00019650 2.37e-25 107.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria,1J7T0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_9860_1 95619.PM1_0217905 4.99e-137 405.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL k141_7809_1 298386.PBPRA2655 4.94e-66 213.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1XT9P@135623|Vibrionales 135623|Vibrionales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_6387_1 1123279.ATUS01000001_gene1384 2.02e-106 323.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1J4UV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iUTI89_1310.UTI89_C0210 HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_6387_3 243233.MCA2795 4.43e-18 79.0 COG1942@1|root,COG1942@2|Bacteria,1N1GC@1224|Proteobacteria,1SB41@1236|Gammaproteobacteria,1XFD8@135618|Methylococcales 135618|Methylococcales S Macrophage migration inhibitory factor - - - - - - - - - - - - MIF k141_18247_1 1121091.AUMP01000002_gene2140 1.38e-37 140.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl k141_17531_1 278963.ATWD01000002_gene681 9.11e-13 67.8 COG1664@1|root,COG1664@2|Bacteria,3Y5MK@57723|Acidobacteria,2JJXQ@204432|Acidobacteriia 204432|Acidobacteriia M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_21702_1 1123517.JOMR01000001_gene1344 7.55e-38 139.0 COG1216@1|root,COG1216@2|Bacteria,1MYS1@1224|Proteobacteria,1S6E5@1236|Gammaproteobacteria,4618S@72273|Thiotrichales 72273|Thiotrichales S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_820_2 13689.BV96_02776 3.62e-08 59.7 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales 204457|Sphingomonadales QU amidohydrolase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3,PD40 k141_20374_1 1288826.MSNKSG1_03380 3.96e-75 230.0 COG0398@1|root,COG0398@2|Bacteria,1RDZ2@1224|Proteobacteria,1RYPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TVP38 TMEM64 family inner membrane protein ydjZ ydjZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_20374_2 1288826.MSNKSG1_03445 2.22e-36 124.0 COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SHCR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Transmembrane anti-sigma factor - - - - - - - - - - - - zf-HC2 k141_1503_1 1278309.KB907103_gene1153 1.43e-147 442.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_18961_1 292415.Tbd_1409 1.66e-83 265.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,1KRS1@119069|Hydrogenophilales 119069|Hydrogenophilales P NnrS protein - - - ko:K07234 - - - - ko00000 - - - NnrS k141_15493_1 1342302.JASC01000014_gene1673 8.15e-117 350.0 COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,3ZVYT@60136|Sulfitobacter 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF853) yjgR - - ko:K06915 - - - - ko00000 - - - DUF853 k141_4300_2 365046.Rta_07670 3.04e-63 226.0 COG3188@1|root,COG3188@2|Bacteria,1R6ZJ@1224|Proteobacteria,2VPW6@28216|Betaproteobacteria,4AGJE@80864|Comamonadaceae 28216|Betaproteobacteria NU usher protein - - - - - - - - - - - - - k141_2909_1 861299.J421_2262 1.9e-60 219.0 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k141_8491_1 2340.JV46_12780 1.97e-99 296.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1J7WB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Tetrahydrodipicolinate N-succinyltransferase N-terminal dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0158 Hexapep,Hexapep_2,THDPS_N_2 k141_18248_2 1188256.BASI01000002_gene3166 1.24e-87 263.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria,3FD4B@34008|Rhodovulum 28211|Alphaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_17532_1 1342302.JASC01000013_gene2778 5.75e-57 179.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,3ZXEJ@60136|Sulfitobacter 28211|Alphaproteobacteria K at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_19636_1 123214.PERMA_0792 4.5e-11 63.9 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K16079,ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2,1.B.4.2.1 - - MtrB_PioB,OMP_b-brl,OMP_b-brl_2 k141_16141_3 1040986.ATYO01000029_gene3394 1.27e-29 111.0 COG2863@1|root,COG2863@2|Bacteria,1R279@1224|Proteobacteria,2TZC9@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome - - - - - - - - - - - - Cytochrome_CBB3 k141_20375_1 1123401.JHYQ01000001_gene1718 2.82e-21 89.4 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,4610J@72273|Thiotrichales 72273|Thiotrichales O Belongs to the glutathione peroxidase family - - - - - - - - - - - - GSHPx k141_20375_2 1216007.AOPM01000105_gene20 3.37e-40 138.0 COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,1S9EB@1236|Gammaproteobacteria,2Q310@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Sensors of blue-light using FAD - - - - - - - - - - - - BLUF k141_7090_1 1288826.MSNKSG1_02213 6.71e-157 452.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_7090_2 1288826.MSNKSG1_02208 2.62e-87 258.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,4670W@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional liuR - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_7090_3 1288826.MSNKSG1_02203 4.37e-285 778.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,46572@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases ivd - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_15494_1 626887.J057_10366 1.85e-48 166.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 k141_14071_2 1123368.AUIS01000008_gene2266 2.31e-43 147.0 COG4244@1|root,COG4244@2|Bacteria,1NB74@1224|Proteobacteria,1SI9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Predicted membrane protein (DUF2231) - - - - - - - - - - - - DUF2231 k141_821_1 1278309.KB907111_gene3352 2.84e-30 115.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XI26@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_821_2 1278309.KB907111_gene3351 2.56e-128 368.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1XK8K@135619|Oceanospirillales 135619|Oceanospirillales S High frequency lysogenization protein HflD homolog hflD - - ko:K07153 - - - - ko00000 - - - DUF489 k141_1586_1 1288826.MSNKSG1_14362 2.02e-131 381.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,465J8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family fmdF - - ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_1586_2 1288826.MSNKSG1_14367 1.49e-201 560.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,466AP@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_1586_3 1288826.MSNKSG1_14372 9.95e-287 784.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,46675@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 k141_1586_4 1288826.MSNKSG1_14377 7.12e-220 637.0 COG0642@1|root,COG0745@1|root,COG1457@1|root,COG0745@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,464VX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_5819_1 870187.Thini_0145 4.19e-26 111.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,45ZMV@72273|Thiotrichales 72273|Thiotrichales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_2,OstA_C k141_19037_1 1278309.KB907106_gene1228 0.0 927.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XH5X@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_19037_3 1278309.KB907106_gene1230 6.06e-143 406.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,1XR0J@135619|Oceanospirillales 135619|Oceanospirillales O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase - - - - - - - - - - - - FKBP_C,FKBP_N k141_5050_1 1288826.MSNKSG1_02183 9.59e-37 131.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,4641B@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0119 Isopropylmalate homocitrate citramalate synthases mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_5050_2 1288826.MSNKSG1_02188 0.0 1169.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465G3@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_3688_1 1288826.MSNKSG1_01653 1.06e-93 273.0 COG0589@1|root,COG0589@2|Bacteria,1N13N@1224|Proteobacteria,1S9AN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T universal stress protein - - - - - - - - - - - - Usp k141_3688_2 1288826.MSNKSG1_01658 0.0 1166.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1T3BM@1236|Gammaproteobacteria,469XC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631,EAL,GGDEF k141_12758_1 1168067.JAGP01000001_gene424 2.04e-190 545.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4602V@72273|Thiotrichales 72273|Thiotrichales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_17627_1 395494.Galf_2644 2.41e-115 344.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,44V3Y@713636|Nitrosomonadales 28216|Betaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD,HD_5 k141_17627_2 686340.Metal_3341 4.06e-05 46.2 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1XE4V@135618|Methylococcales 135618|Methylococcales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC - 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS k141_20443_1 377629.TERTU_0418 1.98e-63 201.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,2PNBR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E CobB/CobQ-like glutamine amidotransferase domain hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_20443_2 1198232.CYCME_0305 5.47e-112 326.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,45ZZE@72273|Thiotrichales 72273|Thiotrichales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_16923_1 305900.GV64_02860 1.31e-40 146.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XIG4@135619|Oceanospirillales 135619|Oceanospirillales M secretion protein - - - ko:K12542 - M00330 - - ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 - - Biotin_lipoyl_2,HlyD,HlyD_3,OEP k141_13452_1 1123399.AQVE01000024_gene2794 2.97e-147 427.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,462E0@72273|Thiotrichales 72273|Thiotrichales C FAD binding domain - - - - - - - - - - - - FAD_binding_4 k141_13452_2 626887.J057_05676 6.94e-22 93.2 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_12057_1 1123057.P872_01835 2.67e-118 368.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_15565_1 1278309.KB907103_gene993 1.43e-70 214.0 2B5HR@1|root,31YCF@2|Bacteria,1RHN4@1224|Proteobacteria,1S7UN@1236|Gammaproteobacteria,1XKG0@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15565_2 1278309.KB907103_gene992 0.0 1519.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1XHS6@135619|Oceanospirillales 135619|Oceanospirillales E aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_15565_3 1278309.KB907103_gene991 1.05e-169 477.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XIR7@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2797) - - - - - - - - - - - - DUF2797 k141_15565_4 1278309.KB907103_gene990 2.94e-49 157.0 COG3139@1|root,COG3139@2|Bacteria,1N7ZT@1224|Proteobacteria,1SC7K@1236|Gammaproteobacteria,1XMEW@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09916 - - - - ko00000 - - - DUF1315 k141_6466_2 305900.GV64_24385 2.63e-168 483.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,1XNR3@135619|Oceanospirillales 135619|Oceanospirillales F Permease family - - - ko:K16345 - - - - ko00000,ko02000 2.A.40.4.2 - - Xan_ur_permease k141_9233_1 1249627.D779_3353 5.86e-266 777.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_9233_2 765914.ThisiDRAFT_2609 1.46e-75 226.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1WYAY@135613|Chromatiales 135613|Chromatiales J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_1618_1 1121939.L861_16700 6.75e-65 203.0 COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria,1XN13@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_1618_2 1122135.KB893138_gene1110 1.96e-06 46.6 COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - YCII k141_18346_1 313628.LNTAR_18625 1.2e-13 67.8 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_18346_2 998674.ATTE01000001_gene2251 2.98e-40 136.0 COG3695@1|root,COG3695@2|Bacteria 2|Bacteria L enzyme binding ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 k141_21188_1 1163617.SCD_n00310 1.08e-58 185.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria 28216|Betaproteobacteria S coa-binding - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 k141_21188_2 1000565.METUNv1_02944 1.26e-24 99.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,2KV20@206389|Rhodocyclales 206389|Rhodocyclales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_19073_1 323261.Noc_0030 8.14e-150 435.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_14164_1 713587.THITH_11255 1.74e-26 113.0 COG3209@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,1RY7B@1236|Gammaproteobacteria,1X2AS@135613|Chromatiales 135613|Chromatiales M TIGRFAM RHS repeat-associated core domain - - - - - - - - - - - - NHL,RHS_repeat k141_10698_1 1123401.JHYQ01000015_gene1405 5.26e-182 530.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales 72273|Thiotrichales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_3709_1 870187.Thini_3152 1.91e-40 153.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein Ccs1 ResB - - - ko:K07399 - - - - ko00000 - - - ResB k141_3709_2 1123400.KB904754_gene1019 1.18e-45 162.0 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales 72273|Thiotrichales O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_199_1 1056820.KB900699_gene1195 1.26e-82 251.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,2PQ83@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_18347_1 412597.AEPN01000003_gene3424 4.91e-135 403.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,2PU0J@265|Paracoccus 28211|Alphaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADH5_C,Proton_antipo_M,Proton_antipo_N k141_21189_1 1317118.ATO8_06856 6.77e-09 56.2 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,4KK0M@93682|Roseivivax 28211|Alphaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid k141_21189_2 388399.SSE37_13056 3.84e-91 274.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_19074_1 1123034.JMKP01000029_gene1430 1.06e-114 350.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,3NIEG@468|Moraxellaceae 1236|Gammaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_21821_1 1288826.MSNKSG1_06743 1.66e-25 102.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,1RMRY@1236|Gammaproteobacteria,464I9@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_28405 - - ko:K09989 - - - - ko00000 - - - VWA_CoxE k141_21821_2 1288826.MSNKSG1_06748 3.43e-198 549.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,1RQ62@1236|Gammaproteobacteria,465MV@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases HA62_21050 - - - - - - - - - - - AAA,AAA_5 k141_21821_3 1288826.MSNKSG1_06753 1.14e-307 859.0 COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,464I4@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - VWA,VWA_3 k141_10699_1 999411.HMPREF1092_02523 2.84e-20 89.7 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,36EQW@31979|Clostridiaceae 186801|Clostridia KT response regulator srrA1 - - - - - - - - - - - Response_reg,Trans_reg_C k141_20471_1 1278309.KB907101_gene305 7.23e-09 53.9 COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,1XMAC@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CYTH k141_20471_2 1278309.KB907101_gene304 4.47e-229 631.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,1XH5Y@135619|Oceanospirillales 135619|Oceanospirillales F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH k141_20471_3 1278309.KB907101_gene303 2.13e-44 148.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,1S9CC@1236|Gammaproteobacteria,1XJZZ@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 k141_5081_1 1452718.JBOY01000025_gene224 2.06e-101 320.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_3710_1 243265.plu2629 1.24e-40 145.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_8585_1 857087.Metme_0137 1.2e-88 286.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XDWG@135618|Methylococcales 135618|Methylococcales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_17651_1 1163617.SCD_n02324 6.45e-89 273.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_7898_1 270374.MELB17_12071 7e-106 314.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,465NH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_7898_2 999141.GME_14810 2.1e-311 858.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1XH2B@135619|Oceanospirillales 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_7898_3 29581.BW37_03314 2.71e-107 318.0 COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,473YG@75682|Oxalobacteraceae 28216|Betaproteobacteria I Enoyl-CoA hydratase/isomerase fadB3 - - - - - - - - - - - ECH_1 k141_7898_4 999141.GME_14800 9.43e-70 214.0 COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,1SAYI@1236|Gammaproteobacteria,1XK12@135619|Oceanospirillales 135619|Oceanospirillales O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - OsmC k141_7175_1 349521.HCH_03644 1.45e-23 101.0 COG2984@1|root,COG2984@2|Bacteria,1PHTD@1224|Proteobacteria,1RRJH@1236|Gammaproteobacteria,1XMRN@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_7175_2 1278309.KB907108_gene1624 4.91e-206 578.0 COG2984@1|root,COG2984@2|Bacteria,1PHTD@1224|Proteobacteria,1RRJH@1236|Gammaproteobacteria,1XMRN@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_7175_3 1278309.KB907108_gene1625 1.21e-227 644.0 28KVB@1|root,2ZABY@2|Bacteria,1R4BA@1224|Proteobacteria,1SXPU@1236|Gammaproteobacteria,1XP0C@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7175_4 1278309.KB907108_gene1626 1.07e-235 665.0 COG0477@1|root,COG2814@2|Bacteria,1MXKN@1224|Proteobacteria,1S1A0@1236|Gammaproteobacteria,1XKDK@135619|Oceanospirillales 135619|Oceanospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_10700_1 1121405.dsmv_1969 2.01e-52 170.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding crp - 2.7.11.1 ko:K10914,ko:K12132,ko:K21564 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko01000,ko01001,ko03000 - - - cNMP_binding k141_16938_1 1288826.MSNKSG1_03061 0.0 1009.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_16938_2 1288826.MSNKSG1_03056 3.79e-292 797.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,4651N@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_16938_3 1288826.MSNKSG1_03051 1.4e-82 243.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,467VK@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ArsC family yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_16938_4 1288826.MSNKSG1_03046 1.07e-239 659.0 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,46580@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1530 Hexapep_2,THDPS_M,THDPS_N k141_16938_5 1288826.MSNKSG1_03041 2.4e-277 758.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,4650N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_16938_6 1288826.MSNKSG1_03036 2.34e-41 136.0 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,468Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_16938_7 1288826.MSNKSG1_03031 7e-114 328.0 COG1278@1|root,COG1278@2|Bacteria,1N0MM@1224|Proteobacteria,1S8XG@1236|Gammaproteobacteria,468TP@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_16938_8 1288826.MSNKSG1_03026 5.12e-87 255.0 2EU93@1|root,33MRI@2|Bacteria,1N7AW@1224|Proteobacteria,1SE4D@1236|Gammaproteobacteria,46BYN@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16938_10 1288826.MSNKSG1_03016 7.95e-106 305.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,46AJQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_16938_11 1288826.MSNKSG1_03011 5.81e-197 548.0 COG3782@1|root,COG3782@2|Bacteria,1MZ3U@1224|Proteobacteria,1T0YB@1236|Gammaproteobacteria,46D1F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1853) - - - ko:K09977 - - - - ko00000 - - - DUF1853 k141_16938_12 1288826.MSNKSG1_03006 1e-248 682.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,463ZP@72275|Alteromonadaceae 1236|Gammaproteobacteria S N-terminal domain of oxidoreductase - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_16938_13 1288826.MSNKSG1_03001 4.81e-275 751.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,4668K@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_16938_14 1288826.MSNKSG1_02996 0.0 1093.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,4642X@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase ycjM - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_5082_2 296591.Bpro_5314 1.79e-05 49.7 2AN3B@1|root,31D0Z@2|Bacteria,1PWKM@1224|Proteobacteria,2VXPG@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4402) - - - - - - - - - - - - DUF4402 k141_8586_1 754476.Q7A_2254 1.11e-133 397.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,46011@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_10701_1 103690.17130955 1.32e-66 216.0 COG1902@1|root,COG1902@2|Bacteria,1FZYT@1117|Cyanobacteria,1HJXU@1161|Nostocales 1117|Cyanobacteria C PFAM NADH flavin oxidoreductase NADH oxidase - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_3016_1 1278309.KB907109_gene3251 3.8e-75 232.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1XHBC@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_3016_2 1278309.KB907109_gene3250 1.29e-259 714.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XHE0@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_18349_2 1123368.AUIS01000017_gene2566 1.37e-15 79.0 COG2199@1|root,COG2199@2|Bacteria,1R2P6@1224|Proteobacteria,1T5UR@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase activity - - - - - - - - - - - - - k141_3712_1 467661.RKLH11_2667 1.74e-29 114.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,3ZGW3@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_3712_2 388401.RB2150_03214 3.96e-57 184.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,3ZG1Y@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_16939_2 1484158.PSNIH1_03025 2.97e-10 60.5 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,3VYCJ@53335|Pantoea 1236|Gammaproteobacteria T SH3 domain protein ygiM GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - ko:K07184 - - - - ko00000 - - - SH3_3 k141_5838_1 1288826.MSNKSG1_15017 1.89e-79 243.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_5838_2 1288826.MSNKSG1_15012 1.28e-183 511.0 COG0300@1|root,COG0300@2|Bacteria,1NH6F@1224|Proteobacteria,1S0XK@1236|Gammaproteobacteria,46ACT@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_5838_3 1288826.MSNKSG1_15007 1.17e-165 464.0 COG0730@1|root,COG0730@2|Bacteria,1P10Q@1224|Proteobacteria,1RY3A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_19129_1 765912.Thimo_2867 3.67e-137 427.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_11442_2 713587.THITH_06490 2.36e-26 100.0 2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,1S9XM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11442_3 1117647.M5M_04850 9.57e-25 93.6 2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria,1J7E6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11442_4 203908.EGG12771 1.69e-09 61.2 COG0446@1|root,KOG1336@2759|Eukaryota,38CNG@33154|Opisthokonta,3NVZ7@4751|Fungi,3UYFU@5204|Basidiomycota,2YCFT@29000|Pucciniomycotina 4751|Fungi S Rieske [2Fe-2S] domain aif1 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006915,GO:0008150,GO:0008152,GO:0008219,GO:0009987,GO:0012501,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0055114 - - - - - - - - - - Pyr_redox_2,Reductase_C,Rieske k141_11442_5 631362.Thi970DRAFT_04049 1.71e-13 73.6 COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,1T2FP@1236|Gammaproteobacteria,1WWXW@135613|Chromatiales 135613|Chromatiales C PFAM 2Fe-2S iron-sulfur cluster binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2 k141_18403_1 1333856.L686_17285 5.49e-17 75.5 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1Z2VS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_16270_1 1288826.MSNKSG1_02033 2.64e-170 481.0 COG0697@1|root,COG0697@2|Bacteria,1R6CU@1224|Proteobacteria,1SZQJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_16270_2 1288826.MSNKSG1_02028 2.02e-292 802.0 COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria,467PM@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA k141_15632_2 396588.Tgr7_1912 7.87e-119 350.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_5871_2 391616.OA238_c15600 2.23e-59 192.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E dehydrogenases and related proteins - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_12154_2 1349767.GJA_455 1.51e-60 196.0 COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,4743P@75682|Oxalobacteraceae 28216|Betaproteobacteria K Bacterial transcriptional repressor C-terminal - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_11,TetR_N k141_2360_1 1278309.KB907100_gene2113 4.11e-63 200.0 COG3907@1|root,COG3907@2|Bacteria,1QV68@1224|Proteobacteria,1SC79@1236|Gammaproteobacteria,1XKEF@135619|Oceanospirillales 135619|Oceanospirillales S PAP2 superfamily - - - ko:K12978 - - - - ko00000,ko01000,ko01005 - - - PAP2 k141_2360_2 1278309.KB907100_gene2112 1.88e-50 173.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,1XM2S@135619|Oceanospirillales 135619|Oceanospirillales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_10011_1 1232683.ADIMK_3865 1.82e-68 208.0 COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1S9GA@1236|Gammaproteobacteria,468KF@72275|Alteromonadaceae 1236|Gammaproteobacteria S HIUase/Transthyretin family - - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin k141_287_1 1249627.D779_0680 4.18e-46 154.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1WWJX@135613|Chromatiales 135613|Chromatiales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_287_2 870187.Thini_3004 1.61e-50 167.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales 72273|Thiotrichales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_21919_1 1485544.JQKP01000005_gene401 1.34e-10 67.8 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,44WBH@713636|Nitrosomonadales 28216|Betaproteobacteria S MMPL family - - - - - - - - - - - - MMPL k141_16287_1 1123288.SOV_1c10630 1.16e-16 81.3 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4H656@909932|Negativicutes 909932|Negativicutes L Terminase RNaseH-like domain - - - - - - - - - - - - - k141_16287_3 1316936.K678_00265 0.00014 43.9 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k141_17741_1 396588.Tgr7_1541 9.56e-112 334.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_19147_1 1122197.ATWI01000009_gene1966 3.8e-12 65.9 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_19147_2 1288826.MSNKSG1_07893 9.85e-152 426.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,4674R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_19147_3 1288826.MSNKSG1_07898 9.99e-94 280.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,464VS@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_20560_1 292415.Tbd_2479 1.48e-42 146.0 COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria 28216|Betaproteobacteria C Nitrate reductase gamma subunit - - - - - - - - - - - - Nitrate_red_gam k141_3105_2 32057.KB217478_gene3623 8.94e-30 116.0 COG0500@1|root,COG2226@2|Bacteria,1G5DI@1117|Cyanobacteria,1HQFD@1161|Nostocales 1117|Cyanobacteria Q Putative methyltransferase - - - - - - - - - - - - Methyltransf_25,Methyltransf_31,Ubie_methyltran k141_5148_2 1265503.KB905165_gene1013 1.1e-18 80.1 2EP7Z@1|root,30H1A@2|Bacteria,1QMY9@1224|Proteobacteria,1TK9D@1236|Gammaproteobacteria,2Q8FH@267889|Colwelliaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_987_1 472759.Nhal_2058 4.13e-84 265.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_5872_1 686578.AFFX01000002_gene908 5.27e-32 121.0 COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S O-Methyltransferase mdmC - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 k141_15633_1 460265.Mnod_0696 1.58e-28 117.0 COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,1JREF@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q PFAM Cytochrome P450 p450 - - - - - - - - - - - p450 k141_288_1 1288826.MSNKSG1_05531 5e-146 420.0 COG3297@1|root,COG3297@2|Bacteria,1N3RU@1224|Proteobacteria,1T05Z@1236|Gammaproteobacteria,46D09@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_21920_1 187272.Mlg_2790 3.45e-89 277.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1WWI2@135613|Chromatiales 135613|Chromatiales IQ PFAM AMP-dependent synthetase and ligase - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_8011_1 1434325.AZQN01000003_gene2279 5.16e-51 165.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_16288_1 1278309.KB907103_gene1147 8.04e-74 232.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1RSQV@1236|Gammaproteobacteria,1XJJG@135619|Oceanospirillales 135619|Oceanospirillales K PFAM flavin reductase domain protein FMN-binding - - - - - - - - - - - - Flavin_Reduct k141_17742_1 1163617.SCD_n00878 2.53e-07 56.6 COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,2VWJT@28216|Betaproteobacteria 28216|Betaproteobacteria P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - - - - - - - - - - CbiQ k141_8641_1 748247.AZKH_p0018 1.11e-75 236.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria 28216|Betaproteobacteria E Belongs to the arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_8641_2 1232683.ADIMK_2996 5.15e-188 533.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,4660J@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein involved in benzoate metabolism benE - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_9321_1 1278309.KB907106_gene1273 2.79e-77 244.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XHDN@135619|Oceanospirillales 135619|Oceanospirillales FP Belongs to the GppA Ppx family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_9321_2 1278309.KB907106_gene1272 1.34e-139 407.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1XHJI@135619|Oceanospirillales 135619|Oceanospirillales H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_2362_1 227086.JGI_V11_92101 1.79e-15 77.4 COG0722@1|root,2QPSU@2759|Eukaryota 2759|Eukaryota E 3-deoxy-7-phosphoheptulonate synthase activity - GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_18418_1 1266914.ATUK01000010_gene1129 2.55e-48 160.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria,1X18N@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_18418_2 1121413.JMKT01000009_gene1951 7.51e-25 102.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,2MAE4@213115|Desulfovibrionales 28221|Deltaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin,cNMP_binding k141_5149_1 207954.MED92_02279 1.9e-49 160.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XJZ5@135619|Oceanospirillales 135619|Oceanospirillales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_5149_2 675814.VIC_000864 2.76e-13 67.4 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XTXJ@135623|Vibrionales 135623|Vibrionales V COG3023 Negative regulator of beta-lactamase expression ampD - 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 k141_6520_2 948565.AFFP02000004_gene727 3.72e-72 218.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1Y8EB@135625|Pasteurellales 135625|Pasteurellales C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters iscU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N k141_6520_3 2340.JV46_04110 3.07e-62 191.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1J6FZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053 Fe-S_biosyn k141_6520_4 396588.Tgr7_2056 1.9e-19 83.6 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1WYVY@135613|Chromatiales 135613|Chromatiales O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB - - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_3106_1 1469245.JFBG01000019_gene1134 1.02e-129 374.0 COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG k141_5873_2 990285.RGCCGE502_12774 9.33e-19 85.5 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,4B8M0@82115|Rhizobiaceae 28211|Alphaproteobacteria E Methionine synthase metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_289_1 1122947.FR7_0206 3.1e-08 56.2 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4H58R@909932|Negativicutes 909932|Negativicutes L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_12155_1 1288826.MSNKSG1_06623 4.6e-103 310.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464G9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_14229_1 1278309.KB907099_gene2596 4.42e-41 140.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1S0IN@1236|Gammaproteobacteria,1XR8I@135619|Oceanospirillales 135619|Oceanospirillales T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_14229_2 1278309.KB907099_gene2597 1.29e-241 673.0 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1T2MN@1236|Gammaproteobacteria,1XS04@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c k141_14229_3 1278309.KB907099_gene2598 1.34e-35 127.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,1S5J1@1236|Gammaproteobacteria,1XJWS@135619|Oceanospirillales 135619|Oceanospirillales L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k141_10012_1 1288826.MSNKSG1_08293 2.37e-81 246.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,465DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_10012_2 1288826.MSNKSG1_08298 6.94e-136 388.0 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,4640R@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the ParA family fleN - - ko:K04562 - - - - ko00000,ko02035 - - - ParA k141_15634_1 765911.Thivi_0069 6.8e-42 144.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WWT5@135613|Chromatiales 135613|Chromatiales U Part of a membrane complex involved in electron transport - - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_15634_2 272943.RSP_3197 7.04e-46 155.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2TZXR@28211|Alphaproteobacteria,1FC8R@1060|Rhodobacter 28211|Alphaproteobacteria C Part of a membrane complex involved in electron transport. Required for nitrogen fixation. Transfers electrons to nitrogenase rnfE - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_5150_1 985054.JQEZ01000001_gene2498 1.74e-23 97.8 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,4N9RH@97050|Ruegeria 28211|Alphaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_14928_1 1249627.D779_4117 3.86e-151 439.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWGD@135613|Chromatiales 135613|Chromatiales T response regulator - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_14928_2 751994.AGIG01000005_gene955 0.000163 44.3 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1J7BB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phosphate-starvation-inducible E - - - ko:K13256 - - - - ko00000 - - - PsiE k141_20561_1 1165096.ARWF01000001_gene834 8.32e-05 45.8 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,2KMV2@206350|Nitrosomonadales 206350|Nitrosomonadales J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA,SnoaL_3 k141_20561_2 314287.GB2207_06863 3.67e-27 103.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1J6VX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S RnfH family Ubiquitin rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_20561_3 1335757.SPICUR_05095 2.56e-28 105.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1WY06@135613|Chromatiales 135613|Chromatiales I Cyclase dehydrase - - - - - - - - - - - - Polyketide_cyc k141_6521_1 243277.VC_1295 3.84e-22 99.8 COG2770@1|root,COG3437@1|root,COG2770@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XT5R@135623|Vibrionales 135623|Vibrionales T COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5 k141_17743_1 1042375.AFPL01000031_gene837 2.65e-50 166.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,46B76@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF882) ycbK - - - - - - - - - - - Peptidase_M15_2 k141_290_1 1163617.SCD_n00811 7.29e-61 203.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria 28216|Betaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_8013_1 614083.AWQR01000046_gene3341 9.23e-29 118.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,4ACM7@80864|Comamonadaceae 28216|Betaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC - - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_2364_1 1469613.JT55_02380 1.42e-60 191.0 COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,2TTZJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q protocatechuate 3,4-dioxygenase pcaG - 1.13.11.3 ko:K00448 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C k141_2364_2 1246448.ANAZ01000016_gene5891 3.17e-07 51.2 COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4EG1V@85012|Streptosporangiales 201174|Actinobacteria CH FAD binding domain pobA - 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R01298 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3 k141_3108_1 371731.Rsw2DRAFT_2903 2.78e-80 244.0 COG1309@1|root,COG1309@2|Bacteria,1PEYE@1224|Proteobacteria,2V7WT@28211|Alphaproteobacteria,1FD19@1060|Rhodobacter 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_21248_1 1278309.KB907099_gene2860 2.96e-124 368.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XHH7@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_21248_2 1278309.KB907099_gene2857 2.17e-82 256.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1XIGG@135619|Oceanospirillales 135619|Oceanospirillales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_12156_1 391615.ABSJ01000042_gene2284 2.15e-06 50.4 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_1710_1 1278309.KB907101_gene464 9.84e-142 411.0 COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,1RQ5G@1236|Gammaproteobacteria,1XIIK@135619|Oceanospirillales 135619|Oceanospirillales E Periplasmic binding protein - - - - - - - - - - - - Peripla_BP_6 k141_1710_2 1122201.AUAZ01000033_gene3239 1.53e-55 178.0 COG4454@1|root,COG4454@2|Bacteria,1RHS5@1224|Proteobacteria,1S81Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Copper-binding protein - - - - - - - - - - - - - k141_5152_1 1027273.GZ77_02935 8.02e-32 117.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_8014_1 1121875.KB907546_gene2196 4.44e-13 67.4 COG3247@1|root,COG3247@2|Bacteria,4NQZ1@976|Bacteroidetes,1I33Q@117743|Flavobacteriia 976|Bacteroidetes S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 k141_2365_1 1177181.T9A_00399 7.25e-81 252.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1XHYF@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_10014_1 1123399.AQVE01000002_gene2319 1.32e-43 155.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_988_2 1278309.KB907100_gene2082 1.67e-214 600.0 COG0665@1|root,COG0665@2|Bacteria,1Q8AY@1224|Proteobacteria,1RSC9@1236|Gammaproteobacteria,1XI3Z@135619|Oceanospirillales 135619|Oceanospirillales E COG0578 Glycerol-3-phosphate dehydrogenase - - - - - - - - - - - - DAO k141_988_3 1278309.KB907100_gene2081 1.51e-91 279.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XHB6@135619|Oceanospirillales 135619|Oceanospirillales M transferase waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N k141_14930_2 1410620.SHLA_15c000850 6.13e-26 103.0 2BVDA@1|root,32QTA@2|Bacteria,1MYBS@1224|Proteobacteria,2UZ7N@28211|Alphaproteobacteria,4BF99@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package k141_20580_2 322710.Avin_38850 4.49e-80 244.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_8032_1 1122599.AUGR01000009_gene2284 4.48e-173 493.0 COG0179@1|root,COG0179@2|Bacteria,1MW82@1224|Proteobacteria,1RQYW@1236|Gammaproteobacteria,1XHSD@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetase - - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FAA_hydrolase,FAA_hydrolase_N k141_8032_2 1278309.KB907111_gene3386 2.3e-23 89.7 28WVJ@1|root,2ZIUX@2|Bacteria,1P4YD@1224|Proteobacteria,1SUP4@1236|Gammaproteobacteria,1XQVF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5262_1 1122137.AQXF01000003_gene2101 1.9e-35 133.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TRBN@28211|Alphaproteobacteria 28211|Alphaproteobacteria EQ N-methylhydantoinase A acetone carboxylase, beta subunit - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A k141_17093_1 765910.MARPU_03540 6.65e-33 117.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales 135613|Chromatiales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_16377_1 1278309.KB907099_gene2851 1.4e-286 806.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XI8D@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_7349_1 192952.MM_2276 6.55e-25 117.0 arCOG02350@1|root,arCOG03567@1|root,arCOG02350@2157|Archaea,arCOG03567@2157|Archaea,2Y7NM@28890|Euryarchaeota,2NBKN@224756|Methanomicrobia 224756|Methanomicrobia T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_2,MEDS,PAS_3,PAS_4,PAS_9 k141_18488_2 608506.COB47_0920 4.72e-12 73.6 COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,24CSU@186801|Clostridia,42F4U@68295|Thermoanaerobacterales 186801|Clostridia S Protein of unknown function DUF115 - - - - - - - - - - - - MAF_flag10 k141_12262_1 1042375.AFPL01000031_gene741 9.82e-30 108.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,46898@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_12262_2 159087.Daro_1973 7.25e-17 79.7 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,2KVUZ@206389|Rhodocyclales 206389|Rhodocyclales I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_10123_1 1278309.KB907100_gene2312 2.57e-103 303.0 COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,1RS6X@1236|Gammaproteobacteria,1XITG@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator, TrmB - - - - - - - - - - - - TrmB k141_10123_2 1122599.AUGR01000005_gene1844 2.15e-83 253.0 COG4380@1|root,COG4380@2|Bacteria,1R3WM@1224|Proteobacteria,1RSP7@1236|Gammaproteobacteria,1XJIM@135619|Oceanospirillales 135619|Oceanospirillales S Putative bacterial lipoprotein (DUF799) - - - - - - - - - - - - DUF799 k141_10123_3 1122599.AUGR01000005_gene1843 4.39e-31 114.0 COG4259@1|root,COG4259@2|Bacteria,1N7DV@1224|Proteobacteria,1S7AS@1236|Gammaproteobacteria,1XM1R@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4810) - - - - - - - - - - - - DUF4810 k141_10123_4 1121935.AQXX01000142_gene2307 2.74e-106 312.0 COG1462@1|root,COG1462@2|Bacteria,1NDU8@1224|Proteobacteria,1RPPY@1236|Gammaproteobacteria,1XJ00@135619|Oceanospirillales 135619|Oceanospirillales M Curli production assembly/transport component CsgG - - - - - - - - - - - - CsgG k141_10123_5 1278309.KB907100_gene2311 3.82e-88 259.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1XK0R@135619|Oceanospirillales 135619|Oceanospirillales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k141_14285_2 400668.Mmwyl1_3917 1.45e-85 266.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,1XJT7@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_14285_3 491952.Mar181_0397 6.43e-107 318.0 COG0169@1|root,COG0169@2|Bacteria,1Q95E@1224|Proteobacteria,1S38H@1236|Gammaproteobacteria,1XMZF@135619|Oceanospirillales 135619|Oceanospirillales E Shikimate dehydrogenase - - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_NADP,Shikimate_DH,Shikimate_dh_N k141_14285_4 1122201.AUAZ01000014_gene262 7.47e-298 830.0 COG1082@1|root,COG3185@1|root,COG1082@2|Bacteria,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,465EP@72275|Alteromonadaceae 1236|Gammaproteobacteria E 4-hydroxyphenylpyruvate dioxygenase lly - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AP_endonuc_2,Glyoxalase,Glyoxalase_5 k141_15002_1 123899.JPQP01000002_gene822 5.69e-20 87.8 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,3T3QN@506|Alcaligenaceae 28216|Betaproteobacteria O DnaJ C terminal domain cbpA - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_15002_2 1116472.MGMO_145c00070 1.66e-27 103.0 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1XFP5@135618|Methylococcales 135618|Methylococcales K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_15002_3 1172186.KB911465_gene4207 1.12e-52 176.0 COG1853@1|root,COG1853@2|Bacteria,2GK9V@201174|Actinobacteria,237U8@1762|Mycobacteriaceae 201174|Actinobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_2463_1 1283284.AZUK01000002_gene2800 3.36e-46 156.0 COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_2463_2 1156937.MFUM_200067 3.91e-28 104.0 2E70X@1|root,331JP@2|Bacteria,46ZFA@74201|Verrucomicrobia,37GYH@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_2463_3 1121403.AUCV01000038_gene4232 1.19e-39 136.0 COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria 1224|Proteobacteria C atp synthase atpC_2 - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_2463_4 1415778.JQMM01000001_gene2175 1.65e-57 191.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_20628_1 314278.NB231_11604 2.63e-151 438.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_20628_2 395493.BegalDRAFT_0738 3.21e-174 504.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales 72273|Thiotrichales T response regulator receiver - - - - - - - - - - - - DUF229,HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_20628_3 323261.Noc_3018 2.05e-17 83.2 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_9394_1 1288826.MSNKSG1_14197 3.72e-73 240.0 COG3055@1|root,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria,1RYPR@1236|Gammaproteobacteria,469I9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1929) - - - - - - - - - - - - DUF1929,Kelch_4 k141_1803_1 1122207.MUS1_06320 2.46e-05 43.5 COG3655@1|root,COG3655@2|Bacteria,1N9J3@1224|Proteobacteria,1SCJ6@1236|Gammaproteobacteria,1XM8V@135619|Oceanospirillales 135619|Oceanospirillales K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 k141_1803_2 383407.XOC_0422 5.61e-28 105.0 COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,1X7FB@135614|Xanthomonadales 135614|Xanthomonadales IQ acyl carrier protein - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_1096_1 314278.NB231_01334 3.35e-58 195.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1WWER@135613|Chromatiales 135613|Chromatiales M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_5263_1 626418.bglu_1g16140 1.19e-73 238.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria,1K2N3@119060|Burkholderiaceae 28216|Betaproteobacteria K PFAM sigma-54 factor interaction domain-containing protein - - - ko:K06714 - - - - ko00000,ko03000 - - - HTH_8,PAS_4,Sigma54_activat k141_22007_1 558884.JRGM01000019_gene1627 1.75e-20 95.5 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1Y4N8@135624|Aeromonadales 135624|Aeromonadales U General secretion pathway protein C exeC - - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC k141_395_1 1123401.JHYQ01000015_gene1407 5.13e-20 82.0 2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,462XP@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_3206_1 472759.Nhal_2289 1.55e-168 478.0 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1WXSW@135613|Chromatiales 135613|Chromatiales P TIGRFAM phosphate binding protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_3206_2 396588.Tgr7_2471 4.12e-126 377.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1WWCF@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_16378_1 1547437.LL06_17660 1.14e-85 263.0 COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,2TYST@28211|Alphaproteobacteria,43J92@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Extracellular solute-binding protein ydcS GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_12263_1 998674.ATTE01000001_gene803 6.82e-24 101.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - - - - - - - - - - STAS,Sulfate_transp k141_12961_1 1123368.AUIS01000011_gene1158 6.79e-43 146.0 COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,1SBYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Heptaprenyl diphosphate synthase component I - - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I k141_12961_3 519989.ECTPHS_03884 4.85e-107 322.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WX7A@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_7350_1 1385935.N836_19965 1.04e-90 276.0 COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1H9U9@1150|Oscillatoriales 1117|Cyanobacteria C NADPH quinone reductase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_6614_1 580331.Thit_1870 0.000193 49.3 COG1409@1|root,COG1409@2|Bacteria,1V7BW@1239|Firmicutes 1239|Firmicutes V Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_18489_1 1353531.AZNX01000041_gene5875 1.56e-07 57.4 COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9US@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - BTAD,Guanylate_cyc,TPR_14,TPR_16 k141_1804_2 2340.JV46_23290 9.84e-40 136.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1J5QA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_21324_1 1288826.MSNKSG1_08608 4.49e-118 344.0 COG2207@1|root,COG2207@2|Bacteria,1R7PM@1224|Proteobacteria,1RYYY@1236|Gammaproteobacteria,46CNV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_21324_2 1288826.MSNKSG1_08603 2.21e-227 627.0 COG2199@1|root,COG3706@2|Bacteria,1R76U@1224|Proteobacteria,1S15R@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg k141_21324_3 1288826.MSNKSG1_08598 1.37e-97 285.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,466ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0234 family yajQ GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K09767 - - - - ko00000 - - - DUF520 k141_21324_4 1288826.MSNKSG1_08593 1.14e-219 611.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,1RPSF@1236|Gammaproteobacteria,46D4F@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0477 Permeases of the major facilitator superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 k141_1097_1 1122207.MUS1_12455 1.13e-151 439.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1XHPF@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_19251_1 1278309.KB907099_gene3059 1.23e-89 268.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,1XHJQ@135619|Oceanospirillales 135619|Oceanospirillales E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_19251_2 207954.MED92_06078 4.58e-57 181.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1XK9R@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_17824_1 1278309.KB907101_gene402 7e-69 232.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XH7V@135619|Oceanospirillales 135619|Oceanospirillales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_17824_2 1278309.KB907101_gene401 1.79e-296 815.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XI4B@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF k141_17824_3 1278309.KB907101_gene400 5.03e-13 68.2 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_2464_1 1479235.KK366039_gene490 2.53e-18 81.6 COG5642@1|root,COG5642@2|Bacteria,1N043@1224|Proteobacteria,1S8U8@1236|Gammaproteobacteria,1XMFQ@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384 k141_15030_1 29495.EA26_09020 3.64e-73 227.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,1Y299@135623|Vibrionales 135623|Vibrionales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin k141_15030_2 28229.ND2E_1944 1.82e-56 186.0 COG0681@1|root,COG0681@2|Bacteria,1R7Z4@1224|Proteobacteria,1RX6N@1236|Gammaproteobacteria,2Q7GV@267889|Colwelliaceae 1236|Gammaproteobacteria U Peptidase S24-like - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_15030_3 1388763.O165_022370 1.98e-09 62.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1YV1R@136845|Pseudomonas putida group 1236|Gammaproteobacteria S ABC transporter yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_16406_1 1278309.KB907106_gene1279 1.28e-65 211.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XH3M@135619|Oceanospirillales 135619|Oceanospirillales H enzyme of heme biosynthesis hemX - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX k141_16406_2 1278309.KB907106_gene1278 1.11e-245 681.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XIR3@135619|Oceanospirillales 135619|Oceanospirillales H biosynthesis protein HemY hemY - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_7 k141_2485_1 1123278.KB893590_gene5411 1.63e-64 211.0 COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,47MCP@768503|Cytophagia 976|Bacteroidetes M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_11559_1 367336.OM2255_10336 8.54e-85 273.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_14308_1 1235457.C404_06025 9.28e-37 136.0 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,2VMRJ@28216|Betaproteobacteria,1K34K@119060|Burkholderiaceae 28216|Betaproteobacteria S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k141_14308_2 195250.CM001776_gene3060 1.18e-08 55.8 COG3484@1|root,COG3484@2|Bacteria,1G118@1117|Cyanobacteria,1GYUW@1129|Synechococcus 1117|Cyanobacteria O proteasome-type protease - - - ko:K07395 - - - - ko00000 - - - Proteasome k141_7371_1 207954.MED92_04689 6.49e-69 213.0 COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S764@1236|Gammaproteobacteria,1XREF@135619|Oceanospirillales 135619|Oceanospirillales E ACT domain - - - - - - - - - - - - ACT_6 k141_7371_2 717774.Marme_0583 9.17e-55 206.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQ69@1236|Gammaproteobacteria,1XJ95@135619|Oceanospirillales 135619|Oceanospirillales NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_17113_2 292415.Tbd_1583 0.000273 43.5 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,1KSMU@119069|Hydrogenophilales 119069|Hydrogenophilales V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_5296_1 1283078.M1I879_9CAUD 2.58e-83 280.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k141_13669_1 1469245.JFBG01000013_gene1927 1.56e-261 722.0 COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria,1WW7Y@135613|Chromatiales 135613|Chromatiales C reductase, dissimilatory-type alpha subunit - - 1.8.99.5 ko:K11180 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_13669_2 396588.Tgr7_2186 4.5e-35 128.0 COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria,1WWM7@135613|Chromatiales 135613|Chromatiales C reductase, dissimilatory-type beta subunit dsrB - 1.8.99.5 ko:K11181 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_21348_1 857087.Metme_4066 1.08e-157 467.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XEHD@135618|Methylococcales 135618|Methylococcales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_21348_2 1042375.AFPL01000054_gene2157 1.31e-06 49.3 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,464E3@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1419 Flagellar GTP-binding protein flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_22022_1 1232683.ADIMK_3131 1.64e-65 209.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RY9X@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PFAM periplasmic binding protein LacI transcriptional regulator - - - ko:K10552 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - Peripla_BP_4 k141_22022_2 1121918.ARWE01000001_gene3564 8.2e-222 619.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_22022_3 314287.GB2207_05497 1.11e-220 611.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3926,iECUMN_1333.ECUMN_4133,iPC815.YPO0060 ADH_N,ADH_zinc_N k141_8752_1 396588.Tgr7_3308 1.52e-29 111.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales 135613|Chromatiales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_10892_1 1278309.KB907103_gene1135 2.79e-79 247.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1XI63@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_10892_2 1278309.KB907103_gene1134 6.4e-139 397.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XHYS@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_19901_1 89187.ISM_11190 3.7e-50 168.0 COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria,2TTUQ@28211|Alphaproteobacteria,46Q2R@74030|Roseovarius 28211|Alphaproteobacteria G transport system, periplasmic component - - - - - - - - - - - - DctP k141_19901_2 1461693.ATO10_12519 2.67e-21 92.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_6637_2 349521.HCH_06066 4.75e-77 242.0 2DBE3@1|root,2Z8QE@2|Bacteria,1N7W6@1224|Proteobacteria,1RNWG@1236|Gammaproteobacteria,1XKWB@135619|Oceanospirillales 135619|Oceanospirillales S Porin-like glycoporin RafY - - - - - - - - - - - - Porin_8 k141_12287_1 672.VV93_v1c32390 9.44e-20 87.4 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1XTV8@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_12287_3 1278309.KB907103_gene1174 2.94e-139 394.0 COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,1RRRU@1236|Gammaproteobacteria,1XHS1@135619|Oceanospirillales 135619|Oceanospirillales E phosphoserine phosphatase thrH - 2.7.1.39,3.1.3.3 ko:K02203 ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230 M00018 R00582,R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HAD,Hydrolase k141_12287_4 1278309.KB907102_gene180 3.94e-125 360.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XJ16@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_17114_1 1458275.AZ34_06660 1.18e-17 84.3 COG2199@1|root,COG3706@2|Bacteria,1R6GI@1224|Proteobacteria,2VM5N@28216|Betaproteobacteria,4A9XC@80864|Comamonadaceae 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF k141_1815_1 1318628.MARLIPOL_04235 3.84e-51 173.0 COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,1SVEG@1236|Gammaproteobacteria,46BGR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_1815_2 1288826.MSNKSG1_11588 9.1e-286 783.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RR6H@1236|Gammaproteobacteria,4664Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_1815_3 1288826.MSNKSG1_11593 0.0 896.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,464DV@72275|Alteromonadaceae 1236|Gammaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_2531_1 1049564.TevJSym_av00160 4.92e-117 350.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_10942_1 1278309.KB907103_gene1044 4.6e-76 249.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XISF@135619|Oceanospirillales 135619|Oceanospirillales M Sterol-sensing domain of SREBP cleavage-activation - - - ko:K07003 - - - - ko00000 - - - MMPL k141_10942_2 1278309.KB907103_gene1045 3.37e-151 429.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XI25@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_10942_3 1278309.KB907103_gene1046 3.69e-224 629.0 COG4773@1|root,COG4773@2|Bacteria,1QWRF@1224|Proteobacteria,1RN9A@1236|Gammaproteobacteria,1XHTP@135619|Oceanospirillales 135619|Oceanospirillales P Receptor - - - - - - - - - - - - - k141_10942_4 1278309.KB907103_gene1047 7.2e-74 226.0 2AVH6@1|root,31M9J@2|Bacteria,1RHYF@1224|Proteobacteria,1S7C2@1236|Gammaproteobacteria,1XQES@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8190_1 1288826.MSNKSG1_03111 0.0 1198.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_8190_2 1288826.MSNKSG1_03106 0.0 876.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_8190_3 1288826.MSNKSG1_03101 1.31e-238 659.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,464MG@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 DXPR_C,DXP_redisom_C,DXP_reductoisom k141_9454_1 765910.MARPU_00890 0.00012 43.9 COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria 1224|Proteobacteria M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE k141_9454_2 717773.Thicy_1389 2.51e-86 279.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,4609P@72273|Thiotrichales 72273|Thiotrichales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_20690_1 1095769.CAHF01000022_gene432 3.54e-49 177.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_22062_1 713586.KB900536_gene2173 5.78e-12 65.9 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWTP@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K10126,ko:K10943 ko02020,ko05111,map02020,map05111 M00504,M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_22062_2 316067.Geob_1632 5.93e-20 92.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase HAMP - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,sCache_3_3 k141_16468_1 1085623.GNIT_0517 5.54e-65 226.0 COG1352@1|root,COG2201@1|root,COG5001@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465FS@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CBS,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_17921_1 580332.Slit_0992 2.7e-42 152.0 COG0191@1|root,COG0191@2|Bacteria,1R6TC@1224|Proteobacteria,2WDHN@28216|Betaproteobacteria,44W8W@713636|Nitrosomonadales 28216|Betaproteobacteria G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k141_12356_1 519989.ECTPHS_08608 7.82e-20 89.7 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1WWU3@135613|Chromatiales 135613|Chromatiales C UPF0313 protein - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_12356_2 909663.KI867149_gene3448 9.13e-22 96.3 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions 1224|Proteobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,RsbU_N,dCache_1 k141_18576_1 2340.JV46_08890 1.69e-83 257.0 COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1J914@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_19324_1 376733.IT41_02285 2.23e-61 193.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,2PV27@265|Paracoccus 28211|Alphaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_19324_2 1208323.B30_11135 1.95e-85 260.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_17175_2 2340.JV46_12090 3.58e-91 273.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1J5CU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_8191_2 1158150.KB906251_gene2 9.83e-11 59.3 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1SB9R@1236|Gammaproteobacteria,1WYI2@135613|Chromatiales 135613|Chromatiales U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_5367_2 90814.KL370891_gene863 1.15e-67 214.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,461E9@72273|Thiotrichales 72273|Thiotrichales GK ROK family - - 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK k141_7446_1 545276.KB898725_gene591 1.4e-127 369.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1WVUK@135613|Chromatiales 135613|Chromatiales C PFAM oxidoreductase FAD NAD(P)-binding domain protein - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_15831_1 396588.Tgr7_0718 1.46e-27 110.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S4J0@1236|Gammaproteobacteria,1WY5K@135613|Chromatiales 135613|Chromatiales S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA k141_15831_2 279714.FuraDRAFT_0308 4.12e-64 207.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KQT4@206351|Neisseriales 206351|Neisseriales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_22063_1 160488.PP_5320 4.64e-15 72.8 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1YVTG@136845|Pseudomonas putida group 1236|Gammaproteobacteria K phosphate regulon transcriptional regulatory protein PhoB phoB GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_22063_2 243365.CV_0563 9.01e-23 100.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,2KQ8N@206351|Neisseriales 206351|Neisseriales T Domain of unknown function (DUF3329) phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS_8 k141_1200_1 314345.SPV1_00095 3.16e-89 291.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_9470_1 153948.NAL212_1147 6.56e-06 46.6 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,372JB@32003|Nitrosomonadales 28216|Betaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_9470_2 998674.ATTE01000001_gene4292 2.96e-50 161.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,460ZF@72273|Thiotrichales 72273|Thiotrichales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_9470_3 1122134.KB893651_gene1787 1.95e-72 220.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1XJIX@135619|Oceanospirillales 135619|Oceanospirillales J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 k141_8210_1 857087.Metme_0456 3.62e-195 568.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XEJP@135618|Methylococcales 135618|Methylococcales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_14363_1 998088.B565_1061 3.23e-48 170.0 COG0303@1|root,COG1763@1|root,COG0303@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1Y445@135624|Aeromonadales 135624|Aeromonadales H MoeA N-terminal region (domain I and II) - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MobB,MoeA_C,MoeA_N k141_11637_1 1278309.KB907101_gene719 1.27e-176 502.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1XHKR@135619|Oceanospirillales 135619|Oceanospirillales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_11637_3 1278309.KB907101_gene721 6.19e-284 779.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales 135619|Oceanospirillales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_7471_1 1278309.KB907099_gene2831 1.82e-39 147.0 COG0591@1|root,COG1842@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,1QX2W@1224|Proteobacteria,1RZNE@1236|Gammaproteobacteria,1XJ1J@135619|Oceanospirillales 135619|Oceanospirillales EKT Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - - k141_7471_2 1278309.KB907099_gene2830 7.09e-165 464.0 COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1XRS5@135619|Oceanospirillales 135619|Oceanospirillales M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_7471_3 1278309.KB907099_gene2829 0.0 998.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XH5K@135619|Oceanospirillales 135619|Oceanospirillales L helicase superfamily c-terminal domain - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k141_7471_4 1278309.KB907099_gene2828 4.47e-165 466.0 COG0583@1|root,COG0583@2|Bacteria,1N8HZ@1224|Proteobacteria,1RR4Z@1236|Gammaproteobacteria,1XJA7@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_7471_5 1278309.KB907099_gene2827 3.32e-232 643.0 COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,1RMHC@1236|Gammaproteobacteria,1XIHV@135619|Oceanospirillales 135619|Oceanospirillales EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_4 k141_2556_1 393595.ABO_1292 2.42e-22 96.7 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1XHFX@135619|Oceanospirillales 135619|Oceanospirillales L ATPase related to the helicase subunit of the Holliday junction resolvase ycaJ - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_2556_2 1095769.CAHF01000007_gene1691 4.67e-64 211.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,472Q2@75682|Oxalobacteraceae 28216|Betaproteobacteria I Transposase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase k141_10239_1 519989.ECTPHS_00690 3.42e-36 134.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales 135613|Chromatiales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_17948_1 759914.BP951000_1651 2.93e-27 111.0 COG0492@1|root,COG0492@2|Bacteria,2J7WA@203691|Spirochaetes 203691|Spirochaetes C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_17202_1 1056820.KB900696_gene3993 3.39e-09 55.5 2ATYA@1|root,31JHY@2|Bacteria,1QAXH@1224|Proteobacteria,1T6D5@1236|Gammaproteobacteria,2PQK4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17202_2 187272.Mlg_1510 1.04e-102 315.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1WX0K@135613|Chromatiales 135613|Chromatiales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_14364_1 1232683.ADIMK_3120 1.16e-33 125.0 28IGK@1|root,2Z8I1@2|Bacteria,1RAH7@1224|Proteobacteria,1RPTY@1236|Gammaproteobacteria,46AEK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_501_1 1121405.dsmv_1530 1.75e-44 155.0 2EUGP@1|root,33MYX@2|Bacteria,1NHBF@1224|Proteobacteria,432H0@68525|delta/epsilon subdivisions,2WXE2@28221|Deltaproteobacteria,2MPEN@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_5390_1 1278309.KB907109_gene3261 1.91e-44 149.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XJBB@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA k141_5390_2 1278309.KB907109_gene3260 2.33e-247 682.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1XIP9@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - - - - - - - - - - - Aminotran_1_2 k141_5390_3 1278309.KB907109_gene3259 2.69e-93 273.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XJPG@135619|Oceanospirillales 135619|Oceanospirillales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_5390_4 1278309.KB907109_gene3258 2.09e-154 439.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1XJ78@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_5390_5 999141.GME_12409 2.75e-16 72.0 2EFYT@1|root,339QZ@2|Bacteria,1NG9A@1224|Proteobacteria,1SH9T@1236|Gammaproteobacteria,1XMQC@135619|Oceanospirillales 135619|Oceanospirillales S MFS transporter - - - - - - - - - - - - - k141_5390_6 1278309.KB907109_gene3256 0.0 1038.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XHSP@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS k141_2557_1 388399.SSE37_07268 6.64e-74 235.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_8211_1 104623.Ser39006_01585 1.46e-130 379.0 COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,1RQD6@1236|Gammaproteobacteria,401K0@613|Serratia 1236|Gammaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_11638_3 1134474.O59_001295 2.25e-52 173.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1FGRE@10|Cellvibrio 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 CTP_transf_3 k141_20703_1 1166018.FAES_2595 3.72e-54 180.0 COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia 976|Bacteroidetes E 1-aminocyclopropane-1-carboxylate deaminase acdS - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP k141_20703_2 155515.JP36_09715 1.56e-09 58.2 COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,1Y6YE@135625|Pasteurellales 135625|Pasteurellales L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair mutH - - ko:K03573 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutH k141_15096_1 1288826.MSNKSG1_01538 7.01e-182 516.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,46AQD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_15096_2 1288826.MSNKSG1_01543 3.02e-123 350.0 2B7YH@1|root,3215N@2|Bacteria,1RJP9@1224|Proteobacteria,1S6AA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_15096_3 1288826.MSNKSG1_01548 6.17e-189 524.0 COG0625@1|root,COG0625@2|Bacteria,1R7YC@1224|Proteobacteria,1S06X@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG0695 Glutaredoxin and related proteins - - - - - - - - - - - - GST_N_3 k141_15096_4 1288826.MSNKSG1_01553 6.28e-200 556.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,466RA@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0656 Aldo keto reductases, related to diketogulonate reductase - - - - - - - - - - - - Aldo_ket_red k141_15096_5 1288826.MSNKSG1_01558 3.58e-18 80.9 2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,1SDJA@1236|Gammaproteobacteria,46C32@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1894_1 765913.ThidrDRAFT_0469 9.75e-46 167.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1X08T@135613|Chromatiales 135613|Chromatiales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_19970_1 1028307.EAE_09905 7.38e-27 114.0 COG0419@1|root,COG1196@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,1R6NJ@1224|Proteobacteria,1RZRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria D ATPase involved in DNA repair - - - - - - - - - - - - - k141_17949_1 472759.Nhal_2364 2.99e-116 350.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_1220_1 1317124.DW2_00165 3.05e-23 95.9 COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,2XKZH@285107|Thioclava 28211|Alphaproteobacteria U Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_1220_2 1317124.DW2_00170 2.51e-98 295.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,2XN2W@285107|Thioclava 28211|Alphaproteobacteria E Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 k141_19338_1 2340.JV46_07240 9.31e-43 142.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1J6KB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_19338_2 1236541.BALL01000062_gene4662 1.38e-60 189.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,2QBN5@267890|Shewanellaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_19338_3 998088.B565_0198 1.42e-26 102.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1Y3QG@135624|Aeromonadales 135624|Aeromonadales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_18598_1 1288826.MSNKSG1_07443 0.0 1041.0 COG0642@1|root,COG0784@1|root,COG3726@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3726@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,463ZD@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase sagS - 2.7.13.3 ko:K20973 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Response_reg k141_18598_2 1288826.MSNKSG1_07438 3.12e-173 484.0 2BJI2@1|root,32DV0@2|Bacteria,1RK8A@1224|Proteobacteria,1S6ZR@1236|Gammaproteobacteria,4697P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18598_3 1288826.MSNKSG1_07433 4.03e-44 152.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,463Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_6700_1 1288826.MSNKSG1_05476 1.46e-259 720.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,46472@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_16505_1 998674.ATTE01000001_gene2920 4.59e-31 121.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4609S@72273|Thiotrichales 72273|Thiotrichales Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_16505_2 762376.AXYL_05746 1.57e-71 229.0 COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,2VIAG@28216|Betaproteobacteria,3T573@506|Alcaligenaceae 28216|Betaproteobacteria P Copper resistance copB - - ko:K07233 - - - - ko00000 - - - CopB k141_16505_3 1123368.AUIS01000004_gene195 3.57e-08 53.5 2A8P7@1|root,30XRT@2|Bacteria,1QGKW@1224|Proteobacteria,1SJ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2934) - - - - - - - - - - - - DUF2934 k141_2558_1 1122599.AUGR01000005_gene1816 1.65e-78 247.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1MV41@1224|Proteobacteria,1RMPJ@1236|Gammaproteobacteria,1XIM4@135619|Oceanospirillales 135619|Oceanospirillales C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 k141_1895_1 388399.SSE37_13041 5.62e-35 133.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_1895_2 367336.OM2255_06270 4.42e-22 87.8 293EG@1|root,2ZQWX@2|Bacteria,1RDP4@1224|Proteobacteria,2U79J@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Elongation factor P - - - - - - - - - - - - - k141_502_1 1026882.MAMP_00738 2.79e-50 177.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,46010@72273|Thiotrichales 72273|Thiotrichales N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux k141_11639_1 1158150.KB906241_gene1006 3.29e-12 61.6 2C07H@1|root,2ZCWQ@2|Bacteria,1P4TT@1224|Proteobacteria,1SV96@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11639_2 216595.PFLU_5022 1.84e-62 197.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1YM65@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria F Nudix N-terminal - - - - - - - - - - - - NUDIX,Nudix_N_2 k141_19385_6 1278309.KB907099_gene3043 6.01e-69 217.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1XHPN@135619|Oceanospirillales 135619|Oceanospirillales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_4767_2 765912.Thimo_3344 3.76e-23 95.1 2DNYF@1|root,32ZSU@2|Bacteria,1N8ZB@1224|Proteobacteria,1S5ZH@1236|Gammaproteobacteria,1WYS0@135613|Chromatiales 135613|Chromatiales S PFAM HupH hydrogenase expression protein, C-terminal conserved region - - - ko:K03618 - - - - ko00000 - - - HupH_C k141_4767_3 1158146.KB907134_gene1475 1.01e-41 142.0 COG0680@1|root,COG0680@2|Bacteria,1RGFM@1224|Proteobacteria,1S4XN@1236|Gammaproteobacteria,1WY9T@135613|Chromatiales 135613|Chromatiales C PFAM Peptidase A31, hydrogen uptake protein - - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI k141_2606_1 1288826.MSNKSG1_00371 7.09e-221 608.0 COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RP4C@1236|Gammaproteobacteria,464ZF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons dhmA - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_2606_3 1288826.MSNKSG1_00381 1.77e-77 231.0 2C8IA@1|root,3412M@2|Bacteria,1NXE0@1224|Proteobacteria,1SQMH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2606_4 1288826.MSNKSG1_00386 1.04e-238 659.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,46525@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease VP2476 - - - - - - - - - - - AI-2E_transport k141_2606_5 1288826.MSNKSG1_00391 1.78e-75 228.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,PG_binding_1 k141_2606_6 1288826.MSNKSG1_00396 9.53e-204 577.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,464EW@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_18035_4 1288826.MSNKSG1_01948 0.0 1046.0 COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,465Q1@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-type multidrug transport system, ATPase component ybhF - - ko:K01990,ko:K13926 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3,ABC_tran k141_18035_5 1288826.MSNKSG1_01943 3.42e-59 191.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,46DF0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like ybhG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_18690_1 1453501.JELR01000002_gene1097 6.16e-70 215.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,466J1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_10319_1 582744.Msip34_1393 2.69e-06 48.5 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales 206350|Nitrosomonadales CI TIGRFAM oxaloacetate decarboxylase alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_10319_2 207954.MED92_09666 5.26e-85 256.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XJND@135619|Oceanospirillales 135619|Oceanospirillales D Maf-like protein maf-2 - - - - - - - - - - - Maf k141_6101_1 1279017.AQYJ01000027_gene1869 4.17e-80 245.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,4644D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_1958_2 314271.RB2654_08527 3.39e-29 104.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k141_17272_1 1123368.AUIS01000006_gene595 4.72e-15 75.1 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,2NBUP@225057|Acidithiobacillales 225057|Acidithiobacillales O Tetratricopeptide repeat - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_17272_2 631362.Thi970DRAFT_00775 1.41e-36 132.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1WXSE@135613|Chromatiales 135613|Chromatiales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_2623_1 1288826.MSNKSG1_11358 5.94e-101 313.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_22173_1 1288826.MSNKSG1_16461 1.01e-44 147.0 COG0589@1|root,COG0589@2|Bacteria,1RG40@1224|Proteobacteria,1S7C5@1236|Gammaproteobacteria,46AX1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_22173_2 1288826.MSNKSG1_16466 3.77e-288 789.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,46A4D@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_22173_3 1288826.MSNKSG1_16471 6.56e-80 240.0 COG3090@1|root,COG3090@2|Bacteria,1R4WJ@1224|Proteobacteria,1RZRQ@1236|Gammaproteobacteria,469X8@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_3991_1 631362.Thi970DRAFT_02291 5.25e-156 463.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales 135613|Chromatiales M HAD-superfamily hydrolase, subfamily IIB - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_19396_1 2340.JV46_15070 9.77e-123 358.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1J5AE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_16563_1 1120983.KB894574_gene1005 1.61e-20 94.0 COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,1JPHB@119043|Rhodobiaceae 28211|Alphaproteobacteria L Transposase zinc-ribbon domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_6102_1 666681.M301_0515 2.28e-17 85.9 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KKJC@206350|Nitrosomonadales 206350|Nitrosomonadales S PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD k141_8281_1 396588.Tgr7_2469 3.37e-131 385.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1WX8S@135613|Chromatiales 135613|Chromatiales P PFAM phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_8281_2 1236542.BALM01000009_gene3047 1.31e-17 79.3 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,2QAEE@267890|Shewanellaceae 1236|Gammaproteobacteria P Protein of unknown function DUF47 VY92_08315 - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_12471_1 1273538.G159_04955 2.03e-118 351.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26E77@186818|Planococcaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_2624_1 1122194.AUHU01000006_gene524 1.74e-111 352.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_11046_1 1056820.KB900674_gene2502 1.42e-28 122.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1T0B8@1236|Gammaproteobacteria,2PPHU@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T Forkhead associated domain - - - ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA k141_17273_1 1453501.JELR01000005_gene1772 3.06e-108 339.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,46514@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_8861_1 1278309.KB907099_gene2978 9.84e-69 216.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XIPN@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_6103_1 768671.ThimaDRAFT_4172 2.13e-97 293.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales 135613|Chromatiales C PFAM Radical SAM - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_18037_1 1283300.ATXB01000001_gene2275 4.94e-108 347.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XEG1@135618|Methylococcales 135618|Methylococcales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_21509_1 754436.JCM19237_3545 3.7e-21 91.7 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,1XSUE@135623|Vibrionales 135623|Vibrionales J Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM - - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_31 k141_21509_2 1163617.SCD_n02079 5.89e-23 90.9 2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria,2W5JW@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_21509_3 555778.Hneap_0560 4.36e-80 253.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WY32@135613|Chromatiales 135613|Chromatiales P SMART Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_21509_4 555778.Hneap_0559 2.6e-15 79.3 28Q4X@1|root,2ZCN0@2|Bacteria,1RA2A@1224|Proteobacteria,1S3SD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21509_6 272943.RSP_2739 5.55e-08 53.5 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2TU5N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_1959_1 1278309.KB907100_gene2222 4.36e-167 471.0 COG0208@1|root,COG0208@2|Bacteria,1QXP8@1224|Proteobacteria,1S1U9@1236|Gammaproteobacteria,1XNB3@135619|Oceanospirillales 135619|Oceanospirillales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k141_19397_1 398512.JQKC01000002_gene1898 5.82e-10 63.9 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_9544_1 1278309.KB907106_gene1360 0.0 989.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XHN6@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_15921_2 243233.MCA1334 6.75e-18 80.1 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1XFGE@135618|Methylococcales 135618|Methylococcales P Part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_18692_2 1286106.MPL1_00377 3.53e-20 91.7 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,4610C@72273|Thiotrichales 72273|Thiotrichales N Belongs to the bacterial flagellin family - - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_20013_1 290398.Csal_2689 1.57e-83 262.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1XI29@135619|Oceanospirillales 135619|Oceanospirillales C Glycolate oxidase glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_16565_1 926556.Echvi_1491 1.14e-45 150.0 COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,47R4J@768503|Cytophagia 976|Bacteroidetes J TIGRFAM export-related chaperone CsaA csaA - - ko:K06878 - - - - ko00000 - - - tRNA_bind k141_569_1 1278309.KB907104_gene930 0.0 1587.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1XIQV@135619|Oceanospirillales 135619|Oceanospirillales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_569_2 1278309.KB907104_gene931 2.92e-237 655.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1XIJ6@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_569_3 1278309.KB907104_gene932 1.02e-215 601.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1XISZ@135619|Oceanospirillales 135619|Oceanospirillales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_569_4 1278309.KB907104_gene933 7.75e-131 380.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XIP7@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_11047_1 1163617.SCD_n00317 3.8e-26 102.0 COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria 28216|Betaproteobacteria P ABC-3 protein - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 k141_11047_2 1123487.KB892846_gene511 1.22e-70 222.0 COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2VHKN@28216|Betaproteobacteria,2KVG9@206389|Rhodocyclales 206389|Rhodocyclales P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA k141_22175_1 1049564.TevJSym_ap00550 1.37e-140 407.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1J5UV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_8283_1 1479237.JMLY01000001_gene2104 1.3e-11 64.7 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465W3@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_8283_2 1123252.ATZF01000014_gene4262 3.93e-14 74.7 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAQ7@91061|Bacilli,27B5N@186824|Thermoactinomycetaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal yxdJ - - - - - - - - - - - Response_reg,Trans_reg_C k141_3368_1 1278309.KB907107_gene1762 0.0 1032.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XIFS@135619|Oceanospirillales 135619|Oceanospirillales CI Oxaloacetate decarboxylase oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_3368_2 1278309.KB907107_gene1761 3.19e-271 747.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XHCI@135619|Oceanospirillales 135619|Oceanospirillales C Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit oadB - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta k141_3368_3 1278309.KB907107_gene1760 1.8e-218 603.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1XIQJ@135619|Oceanospirillales 135619|Oceanospirillales BQ deacetylase - - - - - - - - - - - - Hist_deacetyl k141_3368_4 1278309.KB907107_gene1759 6.33e-314 864.0 COG2204@1|root,COG2204@2|Bacteria,1QVPI@1224|Proteobacteria,1T2FZ@1236|Gammaproteobacteria,1XJ56@135619|Oceanospirillales 135619|Oceanospirillales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_3368_5 1122599.AUGR01000010_gene1040 7.04e-82 259.0 COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,1S3X1@1236|Gammaproteobacteria,1XKK8@135619|Oceanospirillales 135619|Oceanospirillales S Flavin containing amine oxidoreductase - - - ko:K06955 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_3368_6 1415778.JQMM01000001_gene1998 1.44e-18 80.5 28TEE@1|root,2ZFNN@2|Bacteria,1P93Z@1224|Proteobacteria,1STGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3368_7 477228.YO5_09645 1.86e-196 547.0 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,1RY4A@1236|Gammaproteobacteria,1Z3RG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E catechol lapB - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_3368_8 62928.azo1852 1.45e-303 833.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,2KUXM@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.85 ko:K10217 ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00569 R02762,R03889,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3368_9 62928.azo1853 4.05e-146 416.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VH5E@28216|Betaproteobacteria,2KXZ7@206389|Rhodocyclales 206389|Rhodocyclales Q Fumarylacetoacetate (FAA) hydrolase family - - 4.2.1.132,4.2.1.80 ko:K18364 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02601,R05864 RC00750,RC02676 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_3368_10 62928.azo1854 6.1e-153 434.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VPRJ@28216|Betaproteobacteria,2KY3X@206389|Rhodocyclales 206389|Rhodocyclales Q COG3971 2-keto-4-pentenoate hydratase - - 4.1.1.77 ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R05374 RC00751,RC02672 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_3368_11 322710.Avin_30590 1.68e-14 68.6 COG1942@1|root,COG1942@2|Bacteria,1NFYJ@1224|Proteobacteria 1224|Proteobacteria S protein 4-oxalocrotonate tautomerase homolog lapI - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase k141_3368_12 497321.C664_02510 1.35e-191 535.0 COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,2VICX@28216|Betaproteobacteria,2KYC3@206389|Rhodocyclales 206389|Rhodocyclales Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds - - 1.2.1.10,1.2.1.87 ko:K18366 ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220 M00569 R00228,R01172,R09097 RC00004,RC00184,RC01195 br01602,ko00000,ko00001,ko00002,ko01000 - - - AcetDehyd-dimer,Semialdhyde_dh k141_3368_13 305700.B447_13229 6.63e-210 585.0 COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,2VNHZ@28216|Betaproteobacteria,2KVYS@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds - - 4.1.3.39,4.1.3.43 ko:K18365 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R00750,R05298 RC00307,RC00371,RC00572 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k141_3368_14 159087.Daro_3809 2.1e-111 328.0 COG1028@1|root,COG1028@2|Bacteria,1R4D3@1224|Proteobacteria,2VMFK@28216|Betaproteobacteria,2KVBB@206389|Rhodocyclales 206389|Rhodocyclales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_14429_3 1049564.TevJSym_aa00020 7.5e-117 338.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1J55G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_14429_4 1123228.AUIH01000024_gene3251 6.18e-83 251.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_14429_5 1452718.JBOY01000056_gene1773 2.27e-35 123.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria 1236|Gammaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_14429_6 745014.OMB55_00001830 7.54e-163 459.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1J4FI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_14429_8 1049564.TevJSym_aa00070 4.05e-48 156.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1J668@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_6104_2 1288826.MSNKSG1_02961 1.51e-151 432.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,46AHI@72275|Alteromonadaceae 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_15922_2 1163617.SCD_n00627 1.09e-36 126.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria 28216|Betaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_15922_3 745014.OMB55_00001810 1.91e-16 76.6 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Forms part of the polypeptide exit tunnel rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_12472_1 1122201.AUAZ01000024_gene794 5.21e-60 217.0 COG0515@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T5IH@1236|Gammaproteobacteria,46DBJ@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT GAF domain - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,Hpt,Pkinase,Response_reg k141_3992_2 379731.PST_1222 2.34e-137 407.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1Z10E@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_18038_2 265072.Mfla_2237 4.56e-89 271.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,2KMVZ@206350|Nitrosomonadales 206350|Nitrosomonadales S membrane transporter protein - - - - - - - - - - - - TauE k141_16566_1 713586.KB900536_gene1841 6.69e-129 405.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_20014_1 1439940.BAY1663_04438 4.64e-89 276.0 COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cofactor biosynthesis protein NifB nifB - - ko:K02585 - - - - ko00000 - - - Fer4_14,Nitro_FeMo-Co,Radical_SAM k141_2625_1 1123518.ARWI01000001_gene367 1.94e-74 226.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_2625_2 748247.AZKH_p0115 8.22e-89 266.0 COG1305@1|root,COG1305@2|Bacteria,1R4TK@1224|Proteobacteria,2VQIV@28216|Betaproteobacteria,2KWGJ@206389|Rhodocyclales 206389|Rhodocyclales E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core k141_18693_1 626887.J057_15435 9.8e-22 100.0 COG4251@1|root,COG5001@1|root,COG4251@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF k141_570_1 1245471.PCA10_42330 9.21e-93 283.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1YESG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E ACT domain lysC GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_8284_1 105559.Nwat_2514 1.98e-18 77.8 COG1396@1|root,COG1396@2|Bacteria,1N3AQ@1224|Proteobacteria,1S8YT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 k141_8284_2 105559.Nwat_2515 1.77e-41 138.0 COG2026@1|root,COG2026@2|Bacteria,1N2YY@1224|Proteobacteria,1SA10@1236|Gammaproteobacteria,1X1F4@135613|Chromatiales 135613|Chromatiales DJ Addiction module toxin, RelE StbE family - - - ko:K07334 - - - - ko00000,ko02048 - - - - k141_8862_2 1288826.MSNKSG1_10603 1.31e-66 202.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,467XS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429,ko:K14048 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta,Urease_gamma k141_8862_3 999141.GME_09429 1.59e-42 140.0 COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,1XK3W@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_gamma k141_2825_2 214092.YPO3816 2.19e-58 189.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,41D5A@629|Yersinia 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_2825_3 1163407.UU7_10057 4.52e-66 206.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1X5VI@135614|Xanthomonadales 135614|Xanthomonadales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_2825_4 521719.ATXQ01000007_gene1102 9.11e-42 138.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1YGUJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C 4Fe-4S binding domain fdx1 - - - - - - - - - - - Fer4 k141_16066_1 1163408.UU9_03932 7.94e-97 296.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12980 - - - - ko00000,ko01005 - - - OMP_b-brl,Surface_Ag_2 k141_13981_1 1417296.U879_02120 8.33e-37 128.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2U98F@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional cueR - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_13981_2 292414.TM1040_0969 3.72e-12 65.9 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,4N9Y5@97050|Ruegeria 28211|Alphaproteobacteria C Sarcosine oxidase subunit beta soxB3 - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO k141_13298_1 1249627.D779_1733 1.97e-191 565.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_11216_1 1121382.JQKG01000054_gene2121 1.61e-09 62.8 COG0628@1|root,COG0628@2|Bacteria,1WIXU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S COGs COG0628 permease - - - - - - - - - - - - AI-2E_transport k141_11216_2 1045856.EcWSU1_00765 9.19e-25 102.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,3X08X@547|Enterobacter 1236|Gammaproteobacteria H Aminotransferase hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 k141_10502_1 1123401.JHYQ01000025_gene3302 3.68e-26 100.0 COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,1S5W6@1236|Gammaproteobacteria,461FH@72273|Thiotrichales 72273|Thiotrichales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_10502_2 754476.Q7A_296 5.59e-19 82.8 COG1357@1|root,COG1357@2|Bacteria,1MZAT@1224|Proteobacteria,1S9V6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pentapeptide - - - - - - - - - - - - Pentapeptide k141_20975_1 1042377.AFPJ01000037_gene2989 2.98e-10 61.6 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,466X1@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_20975_2 629265.PMA4326_10655 1.3e-38 149.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1Z72X@136849|Pseudomonas syringae group 1236|Gammaproteobacteria E Domain of unknown function (DUF3488) tgpA - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_9106_1 243365.CV_3791 1.03e-24 94.4 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,2KRBG@206351|Neisseriales 206351|Neisseriales G peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_7723_1 29850.GGTG_09456T0 1.27e-15 79.0 COG2145@1|root,2QS2M@2759|Eukaryota,38EVB@33154|Opisthokonta,3NTW4@4751|Fungi,3QQ75@4890|Ascomycota,2123A@147550|Sordariomycetes,41J8N@639021|Magnaporthales 4751|Fungi G Hydroxyethylthiazole kinase THI6 GO:0003674,GO:0003824,GO:0004417,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016765,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.50 ko:K14154 ko00730,ko01100,map00730,map01100 M00127 R03223,R04448,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - HK,TMP-TENI k141_7723_2 396588.Tgr7_2419 1.65e-54 179.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1WXAI@135613|Chromatiales 135613|Chromatiales H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_11217_1 1278309.KB907107_gene1702 5.65e-38 133.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria,1XJ9S@135619|Oceanospirillales 135619|Oceanospirillales U PFAM MotA TolQ ExbB proton channel - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_11217_2 1278309.KB907107_gene1701 4.24e-109 322.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1XK89@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar motor protein - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_15388_1 1487923.DP73_21515 2.02e-34 129.0 COG0730@1|root,COG0730@2|Bacteria,1U7SH@1239|Firmicutes,247QA@186801|Clostridia,261CB@186807|Peptococcaceae 186801|Clostridia S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_12604_1 187272.Mlg_2496 1.68e-82 268.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales 135613|Chromatiales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_18176_5 391624.OIHEL45_02970 2.53e-45 159.0 COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metal-binding integral membrane protein - - - - - - - - - - - - DUF2182 k141_18176_6 1288826.MSNKSG1_10028 2.24e-116 337.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria,466WX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q dithiol-disulfide isomerase involved in polyketide biosynthesis - - - - - - - - - - - - DSBA k141_18176_7 1288826.MSNKSG1_10023 7.34e-127 361.0 COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,464CE@72275|Alteromonadaceae 1236|Gammaproteobacteria J translational elongation yeiP GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_18176_8 1288826.MSNKSG1_10018 1.25e-146 415.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rsuA - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_18176_9 1288826.MSNKSG1_10013 0.0 887.0 COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria,465Y4@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4303 Ethanolamine ammonia-lyase, large subunit eutB - 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutB k141_18176_10 1288826.MSNKSG1_10008 6.64e-173 485.0 COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,1RQ2T@1236|Gammaproteobacteria,466JB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the EutC family eutC - 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutC k141_18176_11 1288826.MSNKSG1_10003 4.87e-94 275.0 2DM33@1|root,31HZ0@2|Bacteria,1RJQ4@1224|Proteobacteria,1S7SM@1236|Gammaproteobacteria,46B2T@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18176_12 1288826.MSNKSG1_09998 3.1e-144 408.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,466WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_18176_13 1288826.MSNKSG1_09993 6.89e-179 498.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1S4TA@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Spermidine synthase - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Spermine_synth k141_18176_15 1288826.MSNKSG1_09983 2.25e-98 286.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1T01F@1236|Gammaproteobacteria,467UT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1522 Transcriptional regulators - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_18176_16 1288826.MSNKSG1_09978 1.79e-281 801.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,463XX@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_16085_1 1266914.ATUK01000011_gene2493 1.95e-56 185.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - - - - - - - - - - AAA_31 k141_14714_1 1278309.KB907102_gene63 1.7e-91 281.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1XI7C@135619|Oceanospirillales 135619|Oceanospirillales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_14714_2 1278309.KB907102_gene62 3.69e-271 752.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XHNY@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_14714_3 1278309.KB907102_gene61 0.0 993.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XHBX@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_14714_4 1278309.KB907102_gene60 2.54e-40 137.0 COG3116@1|root,COG3116@2|Bacteria 2|Bacteria D cell division ftsL GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_14714_5 1278309.KB907102_gene59 2.5e-207 575.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1XIB9@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_14714_6 1278309.KB907102_gene58 2.24e-94 276.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1XJJI@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ k141_14714_7 1278309.KB907102_gene50 2.57e-175 491.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XHFQ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_17460_1 95619.PM1_0206645 8.13e-186 531.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_17460_2 1163617.SCD_n02485 2.69e-23 99.4 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria 28216|Betaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_21009_1 349521.HCH_00432 2.25e-170 483.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XH8Q@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12,1.2.1.72 ko:K00134,ko:K03472 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 R01061,R01825 RC00149,RC00242 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_21009_2 626887.J057_19740 2.05e-59 198.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_11913_1 522306.CAP2UW1_3768 1.11e-79 252.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,1KPN0@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_2839_1 258594.RPA0270 1.48e-28 115.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,3JU6C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_2839_2 1123399.AQVE01000020_gene1679 8.24e-40 145.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,46024@72273|Thiotrichales 72273|Thiotrichales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_21651_1 1288826.MSNKSG1_05531 1.2e-121 357.0 COG3297@1|root,COG3297@2|Bacteria,1N3RU@1224|Proteobacteria,1T05Z@1236|Gammaproteobacteria,46D09@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_21651_2 1288826.MSNKSG1_05536 1.54e-104 304.0 COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1SCSU@1236|Gammaproteobacteria,46CTA@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspM - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM k141_21651_3 1288826.MSNKSG1_05541 1.9e-158 444.0 COG0454@1|root,COG0456@2|Bacteria,1R8SB@1224|Proteobacteria,1T3AU@1236|Gammaproteobacteria,46DH0@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 k141_21651_4 1288826.MSNKSG1_05546 1.57e-195 549.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,46406@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim k141_7034_1 1278309.KB907107_gene1711 1.73e-215 601.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XH8G@135619|Oceanospirillales 135619|Oceanospirillales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_7034_2 1278309.KB907107_gene1712 4.09e-133 382.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1XJFX@135619|Oceanospirillales 135619|Oceanospirillales N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_7034_3 1278309.KB907107_gene1713 1.5e-47 153.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1XMC2@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar biosynthetic protein FliQ fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_7034_4 1278309.KB907107_gene1714 1.19e-140 400.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XHDM@135619|Oceanospirillales 135619|Oceanospirillales N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_7034_5 1042375.AFPL01000054_gene2151 9.88e-30 112.0 COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,468FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG3190 Flagellar biogenesis protein fliO - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_7034_6 1232683.ADIMK_1541 1.25e-48 159.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,467MM@72275|Alteromonadaceae 1236|Gammaproteobacteria N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C,FliN_N k141_7034_7 1278309.KB907107_gene1717 6.44e-216 598.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1XHYT@135619|Oceanospirillales 135619|Oceanospirillales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_7034_8 1278309.KB907107_gene1718 4.23e-77 235.0 COG1580@1|root,COG1580@2|Bacteria,1N2N9@1224|Proteobacteria,1SAF0@1236|Gammaproteobacteria,1XM0N@135619|Oceanospirillales 135619|Oceanospirillales N Controls the rotational direction of flagella during chemotaxis - - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_10520_1 555500.I215_14506 5.32e-75 237.0 COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1HZCR@117743|Flavobacteriia 976|Bacteroidetes G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_4222_1 1121127.JAFA01000029_gene2554 3.27e-15 73.2 2AGD8@1|root,316J0@2|Bacteria,1PXP5@1224|Proteobacteria,2WD20@28216|Betaproteobacteria,1K937@119060|Burkholderiaceae 28216|Betaproteobacteria S Ion channel - - - - - - - - - - - - Ion_trans_2 k141_11914_1 1121459.AQXE01000003_gene1117 2.26e-25 110.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,42MXD@68525|delta/epsilon subdivisions,2WKDU@28221|Deltaproteobacteria,2MAUZ@213115|Desulfovibrionales 28221|Deltaproteobacteria I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc k141_2840_1 999611.KI421504_gene461 7.71e-27 106.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,280P8@191028|Leisingera 28211|Alphaproteobacteria EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_9118_1 1288826.MSNKSG1_14487 7.29e-229 636.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,465MW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Hexapep,Hexapep_2,NTP_transf_3 k141_9118_2 1288826.MSNKSG1_14482 0.0 1132.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,464V8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281 GATase_6,SIS k141_21010_1 1132855.KB913035_gene322 1.06e-69 224.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,2KM19@206350|Nitrosomonadales 206350|Nitrosomonadales EGP PFAM Major Facilitator Superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_14003_2 1226994.AMZB01000133_gene4828 0.000563 41.2 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1YD2I@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_5656_1 1278309.KB907103_gene1082 1.98e-157 452.0 28Q0R@1|root,2ZCJH@2|Bacteria,1RCAM@1224|Proteobacteria,1S3AM@1236|Gammaproteobacteria,1XJKX@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3080) - - - - - - - - - - - - DUF3080 k141_12615_1 1278309.KB907100_gene2349 2.15e-90 275.0 COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,1RRBY@1236|Gammaproteobacteria,1XIJA@135619|Oceanospirillales 135619|Oceanospirillales S membrane protein, required for spore maturation in B.subtilis - - - - - - - - - - - - Gate k141_12615_2 1278309.KB907100_gene2348 3.5e-82 244.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1S60K@1236|Gammaproteobacteria,1XRD5@135619|Oceanospirillales 135619|Oceanospirillales I Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_12615_3 1278309.KB907100_gene2347 1.18e-203 566.0 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1XH4P@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate-binding protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_12615_4 1278309.KB907100_gene2346 0.0 1313.0 COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1XHZ0@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter permease - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_12615_5 1278309.KB907100_gene2345 9.62e-76 241.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate transport system permease protein - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_754_1 314278.NB231_01274 1.07e-122 379.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_6318_1 1122197.ATWI01000008_gene2435 1.45e-64 211.0 COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,1S2YT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG1073 Hydrolases of the alpha beta superfamily yfhR - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_6318_2 95619.PM1_0205535 1.01e-112 358.0 28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,1RRQ0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 k141_6318_3 1122951.ATUE01000006_gene867 1.52e-45 153.0 2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria,3NKN6@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3015) - - - - - - - - - - - - DUF3015 k141_6318_4 1026882.MAMP_01371 2.5e-83 255.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales 72273|Thiotrichales I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_6318_5 1049564.TevJSym_aq00130 9.64e-71 219.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1J5X6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0241 Histidinol phosphatase and related phosphatases gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iJN746.PP_0059 Hydrolase_like k141_6318_7 713586.KB900536_gene2049 3.92e-137 414.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales 135613|Chromatiales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_11916_1 1236959.BAMT01000007_gene2667 1.27e-15 76.6 COG3087@1|root,COG3087@2|Bacteria,1RIU5@1224|Proteobacteria,2VTKT@28216|Betaproteobacteria,2KMUG@206350|Nitrosomonadales 206350|Nitrosomonadales D PFAM Sporulation domain protein - - - - - - - - - - - - SPOR k141_20288_2 1123514.KB905899_gene1567 6.4e-65 206.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales 72273|Thiotrichales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_4224_1 1188256.BASI01000007_gene2239 2.78e-27 110.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,3FCGC@34008|Rhodovulum 28211|Alphaproteobacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_4224_2 999611.KI421504_gene1449 6.37e-44 150.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,27ZFJ@191028|Leisingera 28211|Alphaproteobacteria HJ Prokaryotic glutathione synthetase, N-terminal domain gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_11252_1 998088.B565_3183 2.07e-45 156.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1Y52B@135624|Aeromonadales 135624|Aeromonadales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_12616_1 795666.MW7_3427 3.36e-75 243.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,1JZNY@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily gsiA - - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_8418_1 754477.Q7C_1499 5.63e-126 366.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,4605X@72273|Thiotrichales 72273|Thiotrichales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_8418_2 999541.bgla_1g29500 1.05e-84 261.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1K1CS@119060|Burkholderiaceae 28216|Betaproteobacteria M glycosyl transferase group 1 gtrA - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_6319_1 1168067.JAGP01000001_gene285 1.15e-125 383.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales 72273|Thiotrichales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_14004_2 314285.KT71_01095 4.09e-18 78.2 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1JAAM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_11381_1 1129794.C427_4176 2.83e-154 443.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1SYUH@1236|Gammaproteobacteria,464G2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_16920_1 292415.Tbd_0574 2.79e-28 103.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,1KTCC@119069|Hydrogenophilales 119069|Hydrogenophilales O Sulfurtransferase TusA - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_16920_2 1449355.JQNR01000005_gene2268 1.02e-08 55.5 COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator icaR - - - - - - - - - - - TetR_N k141_19709_1 883078.HMPREF9695_01275 1.05e-21 92.0 COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2U7AD@28211|Alphaproteobacteria,3JYIX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_886_1 870187.Thini_4285 1.04e-16 79.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_10674_1 314271.RB2654_08672 4.28e-103 322.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family dmgdh2 - 1.5.8.4 ko:K00315 ko00260,ko01100,map00260,map01100 - R01565 RC00181 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C k141_5045_2 1278309.KB907100_gene1981 1.22e-288 790.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XH2G@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_5045_3 1122201.AUAZ01000009_gene2789 3.75e-60 189.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,468FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_13448_1 1278309.KB907104_gene934 0.0 1166.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1XIJ8@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,2.5.1.19 ko:K00210,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025 R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_13448_2 1278309.KB907104_gene935 9.68e-133 379.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1XJAC@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_13448_3 1278309.KB907104_gene936 0.0 921.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XHWF@135619|Oceanospirillales 135619|Oceanospirillales J Ribosomal protein S1-like RNA-binding domain - - - - - - - - - - - - S1 k141_13448_4 1278309.KB907104_gene937 3.46e-62 191.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1XKR3@135619|Oceanospirillales 135619|Oceanospirillales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_13448_5 1278309.KB907104_gene938 6.3e-48 155.0 2EK9Z@1|root,32Z3I@2|Bacteria,1NC8M@1224|Proteobacteria,1SCYF@1236|Gammaproteobacteria,1XQXH@135619|Oceanospirillales 135619|Oceanospirillales S Lipopolysaccharide assembly protein A domain - - - ko:K08992 - - - - ko00000 - - - LapA_dom k141_13448_6 1278309.KB907104_gene939 1.08e-125 369.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XHIB@135619|Oceanospirillales 135619|Oceanospirillales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7 k141_12750_1 1469613.JT55_02820 3.47e-64 223.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,3FE0U@34008|Rhodovulum 28211|Alphaproteobacteria S TamB, inner membrane protein subunit of TAM complex tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_14855_1 1288826.MSNKSG1_02228 1.94e-218 607.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_21787_2 998674.ATTE01000001_gene2545 2.03e-30 115.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - AhpC-TSA,Thioredoxin k141_9915_2 375286.mma_2931 1.27e-19 84.0 COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,474XI@75682|Oxalobacteraceae 28216|Betaproteobacteria S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_9915_3 740709.A10D4_04645 3.4e-77 244.0 COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,2QEZH@267893|Idiomarinaceae 1236|Gammaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily rlmM GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 ko:K06968 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_8570_2 351016.RAZWK3B_15628 2.14e-82 251.0 COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2TQUF@28211|Alphaproteobacteria,2P11N@2433|Roseobacter 28211|Alphaproteobacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS k141_6451_1 1046714.AMRX01000006_gene2640 3.48e-81 247.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_11382_1 395493.BegalDRAFT_1201 1.52e-87 263.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,460FX@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_7867_1 1288826.MSNKSG1_16226 4.67e-152 427.0 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,1S3KS@1236|Gammaproteobacteria,466K1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - CbiM k141_7867_2 1288826.MSNKSG1_16221 0.0 1031.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4647C@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family sulP - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_7867_3 1288826.MSNKSG1_16216 2.35e-209 578.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,464NE@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases blh - - - - - - - - - - - Lactamase_B k141_7867_4 1288826.MSNKSG1_16211 0.0 952.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R895@1224|Proteobacteria,1RSDW@1236|Gammaproteobacteria,467PI@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - GAF,GGDEF,PAS_3 k141_7867_5 1288826.MSNKSG1_16206 2.04e-181 505.0 COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,466VH@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_7867_6 1288826.MSNKSG1_16201 0.0 1004.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,465UH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - - - - - - - - - - AMP-binding,Haem_oxygenas_2 k141_2992_1 879243.Poras_1379 4.84e-28 112.0 COG3103@1|root,COG3103@2|Bacteria,4NIB7@976|Bacteroidetes,2FQFE@200643|Bacteroidia,22X8V@171551|Porphyromonadaceae 976|Bacteroidetes T Sh3 type 3 domain protein - - - - - - - - - - - - - k141_2992_2 504472.Slin_2939 6.92e-27 106.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47JEN@768503|Cytophagia 976|Bacteroidetes S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_17624_1 472759.Nhal_2414 1.1e-126 374.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales 135613|Chromatiales F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_5813_1 1056820.KB900642_gene414 2.04e-140 424.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,2PMIW@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NT Signal transducing histidine kinase, homodimeric domain cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_887_1 1530186.JQEY01000007_gene3174 2.85e-07 51.6 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_887_2 1122614.JHZF01000013_gene3867 2.75e-49 172.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria,2PEYP@252301|Oceanicola 28211|Alphaproteobacteria V MatE matE - - - - - - - - - - - MatE k141_12751_1 580332.Slit_2585 1.4e-36 132.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,44VS6@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_12751_2 472759.Nhal_0767 4.07e-12 66.6 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales 135613|Chromatiales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_13449_1 1278309.KB907101_gene632 7.59e-116 346.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XI7E@135619|Oceanospirillales 135619|Oceanospirillales P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB - - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - - NhaB k141_3687_1 472759.Nhal_3898 6.27e-83 255.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales 135613|Chromatiales P PFAM CBS domain - - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_3687_2 105559.Nwat_0339 2.63e-20 94.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales 135613|Chromatiales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_20437_1 1283300.ATXB01000001_gene2457 4.71e-15 71.6 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1XFB8@135618|Methylococcales 135618|Methylococcales U Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_20437_2 713586.KB900536_gene312 5.14e-21 94.4 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_14140_1 1163617.SCD_n01613 1.25e-189 546.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria 28216|Betaproteobacteria P Ferrous iron transport protein B feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_18314_1 555778.Hneap_1970 2.03e-163 476.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_7868_1 1120953.AUBH01000003_gene2195 4.79e-29 108.0 COG3516@1|root,COG3516@2|Bacteria,1RBNB@1224|Proteobacteria,1S2BT@1236|Gammaproteobacteria,467Q1@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria impB - - ko:K11901 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA k141_7868_2 1278309.KB907104_gene815 1.22e-49 172.0 COG3515@1|root,COG3515@2|Bacteria,1MWDQ@1224|Proteobacteria,1RQXI@1236|Gammaproteobacteria,1XMPX@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ vasJ - - ko:K11910 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - ImpA_N,T6SS_VasJ k141_21788_1 870187.Thini_1279 2.35e-98 295.0 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_5814_1 1288826.MSNKSG1_10738 4.69e-161 456.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate epd GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043891,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048001,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.2.1.12,1.2.1.72 ko:K00134,ko:K03472 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 R01061,R01825 RC00149,RC00242 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - iYL1228.KPN_03356 Gp_dh_C,Gp_dh_N k141_20439_1 1002340.AFCF01000032_gene3819 4.68e-82 254.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,34EEK@302485|Phaeobacter 28211|Alphaproteobacteria G Glucose / Sorbosone dehydrogenase yliI GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 ko:K00117,ko:K21430 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - GSDH k141_12051_1 3067.XP_002959112.1 9.33e-07 52.8 COG1335@1|root,KOG4044@2759|Eukaryota,37VP4@33090|Viridiplantae,34I06@3041|Chlorophyta 3041|Chlorophyta Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_12051_2 1218352.B597_006495 9.65e-36 136.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1YZQD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_9220_1 2340.JV46_14980 9.11e-133 408.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1J4CD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_9220_2 402626.Rpic_1285 5.52e-44 156.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1JZSU@119060|Burkholderiaceae 28216|Betaproteobacteria M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_21789_1 1278309.KB907101_gene483 1.8e-106 311.0 COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,1XKBQ@135619|Oceanospirillales 135619|Oceanospirillales S Lysine exporter protein (LYSE YGGA) - - - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE k141_5048_1 714943.Mucpa_1936 1.42e-41 156.0 COG1680@1|root,COG1680@2|Bacteria,4NGX3@976|Bacteroidetes,1ISWT@117747|Sphingobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_185_1 1232683.ADIMK_2707 9.76e-79 247.0 COG1577@1|root,COG1577@2|Bacteria,1NF04@1224|Proteobacteria,1RPXQ@1236|Gammaproteobacteria,46C8E@72275|Alteromonadaceae 1236|Gammaproteobacteria I GHMP kinases C terminal - - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_21813_1 376733.IT41_17080 7.51e-107 321.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,2PUQU@265|Paracoccus 28211|Alphaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_2273_1 1123514.KB905899_gene1741 2.5e-54 185.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,1RWVW@1236|Gammaproteobacteria,462W1@72273|Thiotrichales 72273|Thiotrichales S Metallo-beta-lactamase superfamily - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Lactamase_B,Lactamase_B_2 k141_1606_1 1288826.MSNKSG1_14467 2.02e-140 400.0 COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,466WY@72275|Alteromonadaceae 1236|Gammaproteobacteria E Allophanate hydrolase subunit 1 kipI - - - - - - - - - - - CT_C_D k141_4408_1 1278309.KB907107_gene1695 1.39e-57 196.0 COG3144@1|root,COG3144@2|Bacteria,1MV22@1224|Proteobacteria,1SCC6@1236|Gammaproteobacteria,1XKD8@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook-length control protein FliK - - - - - - - - - - - - Flg_hook k141_4408_2 1278309.KB907107_gene1694 3.65e-135 385.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1XJI8@135619|Oceanospirillales 135619|Oceanospirillales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran k141_4408_3 1278309.KB907107_gene1693 2.38e-137 392.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,1XIZ7@135619|Oceanospirillales 135619|Oceanospirillales O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_4408_4 1278309.KB907107_gene1692 6.3e-170 475.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1XHCY@135619|Oceanospirillales 135619|Oceanospirillales O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm k141_4408_5 1278309.KB907107_gene1691 1.21e-20 82.8 COG3114@1|root,COG3114@2|Bacteria 2|Bacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735 CcmD k141_4408_6 1278309.KB907107_gene1690 5.4e-87 258.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1XJZE@135619|Oceanospirillales 135619|Oceanospirillales O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE k141_4408_7 1278309.KB907107_gene1689 2.72e-136 403.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales 135619|Oceanospirillales O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_21814_1 314275.MADE_000001021840 2.12e-10 61.6 COG2980@1|root,COG2980@2|Bacteria,1N0JN@1224|Proteobacteria,1SAG4@1236|Gammaproteobacteria,467GS@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 LptE k141_21814_2 243233.MCA1453 4.18e-16 77.8 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XDZ5@135618|Methylococcales 135618|Methylococcales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_9227_1 396588.Tgr7_1371 1.42e-84 273.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_3699_2 1278309.KB907105_gene1392 0.0 1033.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1XHB1@135619|Oceanospirillales 135619|Oceanospirillales T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9 k141_900_1 1485544.JQKP01000001_gene1144 3.97e-62 198.0 COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,2WAP5@28216|Betaproteobacteria,44WER@713636|Nitrosomonadales 28216|Betaproteobacteria S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 k141_900_2 1121413.JMKT01000009_gene2159 3.43e-46 152.0 COG3324@1|root,COG3324@2|Bacteria,1N9ZV@1224|Proteobacteria,430FM@68525|delta/epsilon subdivisions,2WW69@28221|Deltaproteobacteria,2MBS4@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_19062_3 1562701.BBOF01000005_gene96 1.7e-07 51.2 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2VVDM@28216|Betaproteobacteria,1K8XQ@119060|Burkholderiaceae 28216|Betaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k141_4409_1 396588.Tgr7_0263 1.6e-118 356.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales 135613|Chromatiales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_10691_2 1454202.PPBDW_60040___1 1.1e-35 135.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1XVW9@135623|Vibrionales 135623|Vibrionales V COG0286 Type I restriction-modification system methyltransferase subunit - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_19834_1 396588.Tgr7_2469 1.9e-84 261.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1WX8S@135613|Chromatiales 135613|Chromatiales P PFAM phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_12209_2 292415.Tbd_2284 2.86e-12 65.1 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,2W0AA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_1032_1 1288826.MSNKSG1_01593 7.66e-30 110.0 COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria,467I3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k141_1032_2 1288826.MSNKSG1_01598 4.89e-37 134.0 COG0697@1|root,COG0697@2|Bacteria,1Q026@1224|Proteobacteria,1S1PS@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_18445_1 396588.Tgr7_2994 1.22e-45 167.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WXM6@135613|Chromatiales 135613|Chromatiales P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_4547_1 1547437.LL06_02265 3.22e-09 58.5 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43IYG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ AMP-binding enzyme C-terminal domain matB - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_4547_2 713586.KB900536_gene1527 9.77e-20 89.7 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amino Acid - - - - - - - - - - - - AA_permease_2 k141_9358_1 1116472.MGMO_128c00130 1.66e-95 296.0 COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,1MU1B@1224|Proteobacteria,1RNFG@1236|Gammaproteobacteria,1XFU7@135618|Methylococcales 135618|Methylococcales C 4Fe-4S dicluster domain - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_11,Form-deh_trans k141_8100_1 2340.JV46_08870 3e-107 341.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1J7JF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C k141_16347_1 537972.ABQU01000044_gene949 0.000315 48.5 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cmeF - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_6589_1 292415.Tbd_2737 3.26e-126 372.0 COG2271@1|root,COG2271@2|Bacteria,1QYIR@1224|Proteobacteria,2WHF2@28216|Betaproteobacteria,1KS5F@119069|Hydrogenophilales 119069|Hydrogenophilales G Sugar (and other) transporter - - - - - - - - - - - - MFS_1 k141_19857_1 1049564.TevJSym_ap00300 2.29e-25 99.8 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1J6XR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_19857_2 1121921.KB898710_gene568 1.02e-56 179.0 2DHXS@1|root,32U9Z@2|Bacteria,1N3G8@1224|Proteobacteria,1SASY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8707_3 1278309.KB907113_gene3328 5.23e-100 291.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1XJC8@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_8707_4 1278309.KB907113_gene3329 0.0 1268.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XH4H@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_11518_3 1122599.AUGR01000004_gene2140 9e-30 115.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XKAP@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_10094_1 589865.DaAHT2_0496 1.58e-41 143.0 COG4619@1|root,COG4619@2|Bacteria,1QTWV@1224|Proteobacteria,42TE6@68525|delta/epsilon subdivisions,2WPHX@28221|Deltaproteobacteria,2MKDH@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM ABC transporter - - - - - - - - - - - - ABC_tran k141_10094_2 589865.DaAHT2_0497 1.41e-06 50.4 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,42Q0J@68525|delta/epsilon subdivisions,2WNYQ@28221|Deltaproteobacteria,2MJB9@213118|Desulfobacterales 28221|Deltaproteobacteria S Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_12927_1 396588.Tgr7_1053 5.83e-70 218.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1WZUJ@135613|Chromatiales 135613|Chromatiales O Thioredoxin - - - ko:K07396 - - - - ko00000 - - - Thioredoxin_5 k141_1771_1 2340.JV46_23210 6.94e-67 208.0 COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_1771_2 857087.Metme_0536 1.2e-53 173.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1XFC1@135618|Methylococcales 135618|Methylococcales H MoaE protein moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE k141_1771_3 1122599.AUGR01000024_gene1358 2.95e-11 60.8 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria,1XMS7@135619|Oceanospirillales 135619|Oceanospirillales H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_1771_4 857087.Metme_0534 9.96e-80 241.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XF23@135618|Methylococcales 135618|Methylococcales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_14979_1 1237149.C900_00735 1.38e-72 246.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12 k141_17803_1 566466.NOR53_1559 1.98e-36 144.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1J5FN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_16348_1 1237149.C900_04592 1.53e-43 158.0 28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein GldM gldM - - - - - - - - - - - GldM_C,GldM_N k141_10843_1 1122197.ATWI01000011_gene443 2.37e-110 343.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_12234_2 906669.G8C7P5_9CAUD 1.92e-20 94.7 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - k141_1055_1 1049564.TevJSym_an00450 3.01e-117 347.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J8WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_1055_2 396588.Tgr7_2896 3.59e-150 428.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1WW0T@135613|Chromatiales 135613|Chromatiales E PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_1055_3 349124.Hhal_0245 1.76e-54 175.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1WYD4@135613|Chromatiales 135613|Chromatiales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_1055_4 439496.RBY4I_2194 5.94e-50 167.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,2TRUH@28211|Alphaproteobacteria 28211|Alphaproteobacteria HJ Belongs to the RimK family rimK - 6.3.2.32 ko:K05844,ko:K14940 ko00680,ko01120,map00680,map01120 - R09401 RC00064,RC00090 ko00000,ko00001,ko01000,ko03009 - - - RimK,Zn_protease k141_2443_1 1288826.MSNKSG1_00451 9.33e-264 724.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,464B2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_2443_2 1288826.MSNKSG1_00456 2.28e-205 570.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,466W8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k141_2443_3 1288826.MSNKSG1_00461 4.12e-274 750.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4646M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S11 family dacA GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664 PBP5_C,Peptidase_S11 k141_2443_4 351348.Maqu_2409 3.29e-26 99.4 COG2921@1|root,COG2921@2|Bacteria,1PJDV@1224|Proteobacteria,1SXYT@1236|Gammaproteobacteria,468E1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 k141_2443_5 1288826.MSNKSG1_00471 4.34e-149 419.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,466J6@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k141_2443_6 1288826.MSNKSG1_00476 9.39e-85 259.0 COG2199@1|root,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,4681U@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain ydaM GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016740,GO:0016772,GO:0016779,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043900,GO:0043902,GO:0044093,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051252,GO:0052621,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1903506,GO:2000112,GO:2001141 2.7.7.65 ko:K19707,ko:K21088 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko03021 - - - GGDEF,PAS_4,PAS_8,PAS_9 k141_374_1 1328313.DS2_13874 6.54e-29 118.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,466C8@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3344 Retron-type reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k141_3189_1 768671.ThimaDRAFT_0112 5.04e-143 425.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales 135613|Chromatiales U sulphate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_3189_2 1122604.JONR01000013_gene3225 6.97e-53 182.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1X4BH@135614|Xanthomonadales 135614|Xanthomonadales P chloride channel clcA - - - - - - - - - - - Voltage_CLC k141_15712_1 1049564.TevJSym_as00740 4.57e-20 84.0 2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,1S5H3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15712_2 765913.ThidrDRAFT_1710 3.59e-81 248.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1WWEI@135613|Chromatiales 135613|Chromatiales H PFAM UBA THIF-type NAD FAD binding - - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_8708_1 1033802.SSPSH_000272 5.12e-60 199.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_13594_1 1349822.NSB1T_11015 1.95e-120 352.0 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,2FMCZ@200643|Bacteroidia,22W1N@171551|Porphyromonadaceae 976|Bacteroidetes S Hydrolase, carbon-nitrogen family - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_19226_2 523791.Kkor_2472 5.99e-84 250.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XK83@135619|Oceanospirillales 135619|Oceanospirillales S EVE domain - - - - - - - - - - - - EVE k141_375_1 1304885.AUEY01000010_gene1688 4.59e-35 131.0 COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,2MKCG@213118|Desulfobacterales 28221|Deltaproteobacteria L TIGRFAM DNA polymerase III, delta holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_3190_1 1266998.ATUJ01000014_gene2419 5.37e-54 177.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2PVH8@265|Paracoccus 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_21308_1 243233.MCA1475 5.52e-72 240.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales 135618|Methylococcales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_11520_1 1247726.MIM_c10030 1.4e-92 297.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,3T36F@506|Alcaligenaceae 28216|Betaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_8709_1 765912.Thimo_1749 3.92e-61 201.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_10845_1 1005395.CSV86_03507 3.6e-96 291.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1YUZU@136845|Pseudomonas putida group 1236|Gammaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 DXPR_C,DXP_redisom_C,DXP_reductoisom k141_1056_2 1415778.JQMM01000001_gene987 1.6e-89 268.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1J4TW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_2444_1 446469.Sked_01060 1.81e-41 148.0 COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria 201174|Actinobacteria G Belongs to the binding-protein-dependent transport system permease family rbsC - - ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2,Peripla_BP_4 k141_6591_1 435908.IDSA_00165 2.82e-08 63.5 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,2QF9N@267893|Idiomarinaceae 1236|Gammaproteobacteria S AsmA-like C-terminal region yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_376_1 402626.Rpic_3263 2.09e-21 94.7 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,1K2Y8@119060|Burkholderiaceae 28216|Betaproteobacteria O Pfam Cytochrome C assembly protein ccsB - - - - - - - - - - - Cytochrom_C_asm k141_5223_1 396588.Tgr7_0332 6.08e-118 351.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales 135613|Chromatiales GM NAD-dependent epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 k141_5223_2 870187.Thini_3264 1.11e-189 540.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,45ZYR@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_5223_3 331678.Cphamn1_0445 4.52e-17 80.5 COG0500@1|root,COG2226@2|Bacteria,1FF0C@1090|Chlorobi 1090|Chlorobi H PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11 k141_21309_1 765912.Thimo_1749 2.21e-72 229.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8710_1 384765.SIAM614_14315 1.58e-17 80.9 COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,2TT79@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_8710_2 1122194.AUHU01000006_gene528 2.59e-39 139.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RS50@1236|Gammaproteobacteria,464VG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component tauC - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_14980_1 751994.AGIG01000008_gene1136 1.88e-11 64.3 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1J5QD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_14980_2 396588.Tgr7_0860 1.28e-179 519.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1WW6M@135613|Chromatiales 135613|Chromatiales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_19228_2 706587.Desti_2842 7.27e-21 85.1 2EUYT@1|root,33NE0@2|Bacteria,1P79U@1224|Proteobacteria,432X2@68525|delta/epsilon subdivisions,2WXB8@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_11521_1 323848.Nmul_A0150 1.17e-58 206.0 COG0421@1|root,COG0477@1|root,COG0421@2|Bacteria,COG2814@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,372RG@32003|Nitrosomonadales 28216|Betaproteobacteria E Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth k141_12928_2 1461693.ATO10_00825 4.11e-21 95.1 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_4564_1 1232683.ADIMK_4107 1.65e-170 481.0 COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,464Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria L PFAM transposase, IS4 family protein insH6 GO:0000271,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006351,GO:0006355,GO:0006629,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009279,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016051,GO:0016070,GO:0016740,GO:0016757,GO:0016758,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019867,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031975,GO:0032196,GO:0032774,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044424,GO:0044444,GO:0044462,GO:0044464,GO:0045226,GO:0045893,GO:0045935,GO:0046379,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1903509,GO:2000112,GO:2001141 - ko:K07481 - - - - ko00000 - - - DDE_Tnp_1,DUF772 k141_2446_1 1123368.AUIS01000041_gene1 1.44e-71 228.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,2NC58@225057|Acidithiobacillales 225057|Acidithiobacillales C Belongs to the citrate synthase family - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_19858_1 1278309.KB907106_gene1319 2.05e-87 261.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XHGE@135619|Oceanospirillales 135619|Oceanospirillales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_19858_2 1278309.KB907106_gene1318 2.05e-66 202.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1XK4T@135619|Oceanospirillales 135619|Oceanospirillales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_19858_3 1232683.ADIMK_0931 1.3e-58 181.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,4677X@72275|Alteromonadaceae 1236|Gammaproteobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_19858_4 1278309.KB907106_gene1316 2.24e-196 544.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XHKX@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB - - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_19858_5 1278309.KB907106_gene1315 5.59e-30 107.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1XKG5@135619|Oceanospirillales 135619|Oceanospirillales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_17073_1 1297570.MESS4_380029 3.52e-50 179.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,43JE0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family torZ - - ko:K08351 ko00780,ko01100,map00780,map01100 - R10127 RC03056 ko00000,ko00001,ko01000,ko02000 5.A.3.4 - - Molybdopterin,Molydop_binding k141_12238_1 335543.Sfum_1220 3.65e-63 212.0 COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2MR17@213462|Syntrophobacterales 28221|Deltaproteobacteria J Elongation factor Tu domain 2 selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 k141_3191_1 756272.Plabr_2027 8.3e-29 111.0 COG3752@1|root,COG3752@2|Bacteria,2IZ0I@203682|Planctomycetes 203682|Planctomycetes S 3-oxo-5-alpha-steroid 4-dehydrogenase - - - - - - - - - - - - DUF1295 k141_3191_3 1411685.U062_00563 1.94e-57 183.0 COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer Membrane Lipoprotein blc4 - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_1058_1 765912.Thimo_2946 1.06e-109 341.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WWPR@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_16351_1 1485545.JQLW01000005_gene1092 9.79e-99 317.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria 1224|Proteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family czcA - - ko:K07239,ko:K15726 - - - - ko00000,ko02000 2.A.6.1,2.A.6.1.2 - - ACR_tran k141_8101_1 519989.ECTPHS_06917 1.24e-82 249.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1WWJC@135613|Chromatiales 135613|Chromatiales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_9519_1 765913.ThidrDRAFT_3516 4.09e-102 309.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales 135613|Chromatiales S Methyltransferase - - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 k141_22138_1 395961.Cyan7425_0624 5.3e-38 144.0 COG0837@1|root,COG0837@2|Bacteria,1G1TJ@1117|Cyanobacteria,3KHBA@43988|Cyanothece 1117|Cyanobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_22138_2 1380347.JNII01000005_gene3591 1.94e-08 56.6 COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4ESDZ@85013|Frankiales 201174|Actinobacteria G TIGRFAM 6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_18655_1 398580.Dshi_0658 3.18e-113 341.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_12440_1 1528106.JRJE01000032_gene2634 1.23e-45 161.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2JUR5@204441|Rhodospirillales 204441|Rhodospirillales E C-terminus of AA_permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2,AA_permease_C k141_16546_1 859657.RPSI07_0697 2.02e-15 73.9 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,1K029@119060|Burkholderiaceae 28216|Betaproteobacteria S Cytochrome c assembly protein ypjD - - - - - - - - - - - Cytochrom_C_asm k141_16546_2 1033802.SSPSH_002045 3.63e-175 503.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorB yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_20719_1 391615.ABSJ01000026_gene110 2.11e-64 215.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding k141_3978_2 1288826.MSNKSG1_06823 8.25e-158 467.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,4675F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_14,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8 k141_6729_2 1288826.MSNKSG1_07053 1.36e-203 563.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,4650D@72275|Alteromonadaceae 1236|Gammaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_6729_3 1288826.MSNKSG1_07058 6.42e-90 264.0 COG1396@1|root,COG1396@2|Bacteria,1P1P9@1224|Proteobacteria,1SRNQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_19 k141_6729_5 1288826.MSNKSG1_07063 3.93e-93 282.0 2AK3X@1|root,3369U@2|Bacteria,1N7U0@1224|Proteobacteria,1SD30@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13812_1 1461693.ATO10_05821 9.79e-49 162.0 COG1175@1|root,COG1175@2|Bacteria,1MVAZ@1224|Proteobacteria,2TRWF@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1175 ABC-type sugar transport systems permease components - - - ko:K17322 ko02010,map02010 M00607 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.35 - - BPD_transp_1 k141_13812_3 314265.R2601_05283 3.49e-28 110.0 COG3839@1|root,COG3839@2|Bacteria,1MU7W@1224|Proteobacteria,2TQNF@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K17325 ko02010,map02010 M00607 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.35 - - ABC_tran,TOBE_2 k141_15886_1 545276.KB898730_gene1486 3.32e-42 144.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1WWRN@135613|Chromatiales 135613|Chromatiales P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_15886_2 717772.THIAE_01910 9.79e-38 139.0 COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria,460Z2@72273|Thiotrichales 72273|Thiotrichales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,LGT k141_19377_1 857087.Metme_1030 0.000152 43.1 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1XDT4@135618|Methylococcales 135618|Methylococcales N TIGRFAM Flagellar basal-body rod - - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_19377_2 472759.Nhal_2327 2.38e-57 194.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1WW6Q@135613|Chromatiales 135613|Chromatiales N basal body rod protein - - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_10290_1 89187.ISM_05730 2.04e-48 157.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,46QV3@74030|Roseovarius 28211|Alphaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_10290_2 1101190.ARWB01000001_gene3876 3.6e-14 72.4 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,36XMT@31993|Methylocystaceae 28211|Alphaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P k141_6083_1 388401.RB2150_13091 3.6e-167 483.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,3ZGAG@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_18011_1 580332.Slit_0868 1.18e-13 71.6 COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria 1224|Proteobacteria C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1 k141_1270_1 500640.CIT292_08808 5.41e-13 65.1 2AHMX@1|root,317ZV@2|Bacteria,1PZIR@1224|Proteobacteria,1SU9H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13118_1 187272.Mlg_0997 0.00029 43.9 COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria,1WWZ5@135613|Chromatiales 135613|Chromatiales P TIGRFAM sulfur relay protein, TusE DsrC DsvC family - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_13118_2 1168067.JAGP01000001_gene771 2.78e-57 185.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,4608K@72273|Thiotrichales 72273|Thiotrichales K Transcriptional regulator - - - - - - - - - - - - Transcrip_reg k141_8273_1 1049564.TevJSym_al00520 1.46e-72 232.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1J578@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC GO:0005575,GO:0005623,GO:0005886,GO:0008104,GO:0008150,GO:0016020,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_8273_2 349521.HCH_06254 2.17e-73 230.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XJBB@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA k141_8273_3 1380387.JADM01000006_gene1180 3.42e-12 67.8 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1XMTM@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14425_1 643867.Ftrac_0222 4.92e-53 173.0 COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,47M9N@768503|Cytophagia 976|Bacteroidetes K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_3983_1 391589.RGAI101_3808 9.53e-62 213.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2TU7G@28211|Alphaproteobacteria,2P4GM@2433|Roseobacter 28211|Alphaproteobacteria O AAA domain - - - - - - - - - - - - AAA_32,Lon_C k141_11690_1 7739.XP_002590720.1 3.12e-45 149.0 2CZEB@1|root,2S9YW@2759|Eukaryota,3AB3P@33154|Opisthokonta,3BUXI@33208|Metazoa,3DB54@33213|Bilateria 33208|Metazoa S Cupin domain - - - - - - - - - - - - Cupin_2 k141_18682_1 1082932.ATCR1_09738 3.37e-26 111.0 COG3735@1|root,COG3735@2|Bacteria,1R7DV@1224|Proteobacteria,2U24S@28211|Alphaproteobacteria,4B7WE@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K09973 - - - - ko00000 - - - TraB k141_21502_1 722419.PH505_dq00010 1.14e-32 121.0 COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,2Q00G@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives ylbG - - - - - - - - - - - HTH_29,rve,rve_2,rve_3 k141_21502_2 314275.MADE_1009785 3.99e-36 134.0 COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,46631@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives ylbG - - - - - - - - - - - HTH_29,rve,rve_2,rve_3 k141_6095_1 1278309.KB907099_gene3021 3.75e-54 174.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1XJVW@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF924 k141_6095_2 1278309.KB907099_gene3020 1.49e-113 333.0 2AAZ1@1|root,310CJ@2|Bacteria,1RF01@1224|Proteobacteria,1S5PA@1236|Gammaproteobacteria,1XK9C@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6095_3 207954.MED92_01414 8.33e-114 330.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,1XIAW@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_3,GST_N k141_6095_4 1278309.KB907099_gene3018 1.1e-52 174.0 28IGK@1|root,2Z8I1@2|Bacteria,1RAH7@1224|Proteobacteria,1RPTY@1236|Gammaproteobacteria,1XJRN@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11035_1 1237149.C900_04094 1.51e-37 141.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_8 k141_6753_1 391615.ABSJ01000027_gene229 5.38e-29 114.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1J4G6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280 Aldedh k141_6753_2 1049564.TevJSym_by00010 1.73e-14 73.9 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1J58M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase III delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_8857_1 631362.Thi970DRAFT_03885 5.09e-82 249.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1WXHM@135613|Chromatiales 135613|Chromatiales IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_10310_1 395493.BegalDRAFT_0856 3.29e-61 204.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_10310_2 342610.Patl_3979 1.22e-111 336.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,2Q0SY@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_1951_2 1288826.MSNKSG1_10853 7.6e-78 233.0 COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,1SDBW@1236|Gammaproteobacteria,468XN@72275|Alteromonadaceae 1236|Gammaproteobacteria S LrgA family - - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA k141_1951_3 1288826.MSNKSG1_10858 0.0 957.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RQJX@1236|Gammaproteobacteria,464B6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - DUF1298,WES_acyltransf k141_1951_4 1288826.MSNKSG1_10863 6.74e-130 369.0 COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1RN9W@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer - - - - - - - - - - - - TetR_N k141_13143_1 391595.RLO149_c001710 1.53e-69 214.0 COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,2P359@2433|Roseobacter 28211|Alphaproteobacteria F Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_17266_2 1288826.MSNKSG1_06613 7.29e-155 441.0 2FFR6@1|root,347NE@2|Bacteria,1P0S4@1224|Proteobacteria,1STKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17266_3 1288826.MSNKSG1_06608 9.84e-138 390.0 2FF8I@1|root,3476D@2|Bacteria,1P1M9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_17266_4 1288826.MSNKSG1_06603 1.21e-45 155.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,466X1@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_21503_1 1158292.JPOE01000002_gene2035 6.96e-54 186.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria 28216|Betaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_22163_1 857087.Metme_4126 7.54e-07 50.4 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XDMX@135618|Methylococcales 135618|Methylococcales H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_22163_2 1123393.KB891330_gene761 6.51e-256 709.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KSCE@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_12461_1 367336.OM2255_06125 8.36e-54 171.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2UC3G@28211|Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_12461_2 633131.TR2A62_3149 4.42e-52 167.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_19391_1 380394.Lferr_0874 3.49e-41 146.0 COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RZYE@1236|Gammaproteobacteria,2NCH5@225057|Acidithiobacillales 225057|Acidithiobacillales S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5 k141_19391_2 765911.Thivi_3043 1.49e-14 75.1 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,1WW06@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_6754_1 76114.ebA3690 2.12e-16 79.0 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2VII5@28216|Betaproteobacteria,2KUUT@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - CbiA,GATase_3 k141_8274_1 1255043.TVNIR_2981 5.59e-29 105.0 COG2154@1|root,COG2154@2|Bacteria,1N7XJ@1224|Proteobacteria,1T12K@1236|Gammaproteobacteria,1X2MX@135613|Chromatiales 135613|Chromatiales H Pterin 4 alpha carbinolamine dehydratase - - - - - - - - - - - - Pterin_4a k141_8274_2 95619.PM1_0216280 2.31e-30 118.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria D chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,MipZ k141_8274_4 1255043.TVNIR_2978 4.65e-40 142.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales 135613|Chromatiales K LysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_9537_1 1278309.KB907103_gene1199 1.51e-68 213.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XJWG@135619|Oceanospirillales 135619|Oceanospirillales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 k141_9537_2 1278309.KB907103_gene1200 3.31e-107 310.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1XHWJ@135619|Oceanospirillales 135619|Oceanospirillales O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_9537_3 1278309.KB907103_gene1201 0.0 1029.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1XHK2@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k141_9537_4 1278309.KB907103_gene1202 1.29e-73 226.0 COG3945@1|root,COG3945@2|Bacteria,1PCE0@1224|Proteobacteria,1SXDY@1236|Gammaproteobacteria,1XPBM@135619|Oceanospirillales 135619|Oceanospirillales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_9537_5 207954.MED92_17157 8.36e-95 279.0 COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,1XP9S@135619|Oceanospirillales 135619|Oceanospirillales P Iron-storage protein - - - - - - - - - - - - Ferritin k141_9537_7 1278309.KB907103_gene1203 0.0 1520.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XNKT@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - - - - - - - - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_6096_1 1469245.JFBG01000061_gene2322 7.46e-116 348.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales 135613|Chromatiales E TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_2615_1 1049564.TevJSym_ag00270 1.27e-09 59.3 COG1801@1|root,COG1801@2|Bacteria,1NJGC@1224|Proteobacteria,1SHUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - - k141_2615_3 1163617.SCD_n01213 5.73e-81 249.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria 28216|Betaproteobacteria M VacJ family lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_13144_2 1049564.TevJSym_ae00870 3.16e-49 164.0 COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria,1J75E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Dihaem cytochrome c - - - - - - - - - - - - DHC k141_1287_1 566466.NOR53_211 2.6e-37 136.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1J4R8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_1287_2 582515.KR51_00013650 2.28e-30 109.0 COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria 1117|Cyanobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_18684_1 1443111.JASG01000004_gene3536 2.73e-34 125.0 COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,3ZV68@60136|Sulfitobacter 28211|Alphaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - - - - - - - - - - LolA k141_15908_1 1288826.MSNKSG1_15686 5.58e-96 279.0 COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria,46AYU@72275|Alteromonadaceae 1236|Gammaproteobacteria S TM2 domain - - - - - - - - - - - - TM2 k141_15908_2 1288826.MSNKSG1_15691 0.0 876.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RQJX@1236|Gammaproteobacteria,464B6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins atfA1 - 2.3.1.20 ko:K00635 ko00561,ko01100,map00561,map01100 M00089 R02251 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - DUF1298,WES_acyltransf k141_568_1 1288826.MSNKSG1_02996 3.04e-68 221.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,4642X@72275|Alteromonadaceae 1236|Gammaproteobacteria G Alpha amylase ycjM - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C k141_568_2 1288826.MSNKSG1_02991 9.07e-299 814.0 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,4647V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_568_3 1288826.MSNKSG1_02986 6.63e-144 409.0 COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,4672I@72275|Alteromonadaceae 1236|Gammaproteobacteria S PFAM Haloacid dehalogenase domain protein hydrolase type 3 yedP - 2.7.1.31,3.1.3.70 ko:K07026,ko:K15918 ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514,R05790 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3,S6PP k141_15332_2 1122599.AUGR01000011_gene4118 1.94e-74 224.0 2E278@1|root,32XDG@2|Bacteria,1NDYE@1224|Proteobacteria,1S8GR@1236|Gammaproteobacteria,1XS8M@135619|Oceanospirillales 135619|Oceanospirillales S Dehydrogenase - - - - - - - - - - - - - k141_15332_3 1278309.KB907099_gene2492 4.13e-192 537.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XHIF@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_15332_4 1278309.KB907099_gene2493 8.86e-169 473.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XH6D@135619|Oceanospirillales 135619|Oceanospirillales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_15332_5 1278309.KB907099_gene2494 1.52e-162 459.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1XHXB@135619|Oceanospirillales 135619|Oceanospirillales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF,QueF_N k141_15332_6 1278309.KB907099_gene2495 9.82e-93 275.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,1XK07@135619|Oceanospirillales 135619|Oceanospirillales C nitroreductase - - - - - - - - - - - - Nitroreductase k141_15332_7 1278309.KB907099_gene2496 2.3e-95 279.0 COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria,1XM52@135619|Oceanospirillales 135619|Oceanospirillales Q COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - YiiD_C k141_15333_1 715451.ambt_21710 2.89e-70 226.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_4159_1 1278309.KB907099_gene2575 5.58e-40 144.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_4159_2 1278309.KB907099_gene2576 5.32e-39 138.0 COG2086@1|root,COG2086@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K03521 - - - - ko00000 - - - ETF k141_4159_4 1278309.KB907099_gene2577 6.62e-215 596.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,1XK88@135619|Oceanospirillales 135619|Oceanospirillales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_4159_5 1278309.KB907099_gene2578 2.24e-158 446.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1XI46@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF k141_4159_6 1278309.KB907099_gene2579 1.19e-68 215.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1XHMV@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_20187_1 1288826.MSNKSG1_09188 0.0 1147.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,466AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_20187_2 1288826.MSNKSG1_09193 0.0 1206.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,463Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases HA62_19490 - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_20187_3 1288826.MSNKSG1_09198 3.65e-72 221.0 COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,1S95Z@1236|Gammaproteobacteria,465PP@72275|Alteromonadaceae 1236|Gammaproteobacteria M SprA-related family - - - - - - - - - - - - SprA-related k141_4160_1 105559.Nwat_2283 1.21e-69 224.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1WXJN@135613|Chromatiales 135613|Chromatiales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_4160_2 1211114.ALIP01000028_gene1434 8.43e-55 196.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales 135614|Xanthomonadales I converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974 k141_20189_2 701176.VIBRN418_08242 6.54e-37 132.0 COG0454@1|root,COG0456@2|Bacteria,1RIMQ@1224|Proteobacteria,1S6A2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Acetyltransferase - - - - - - - - - - - - Acetyltransf_1 k141_4162_1 349521.HCH_04101 6.54e-60 193.0 COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XP7R@135619|Oceanospirillales 135619|Oceanospirillales G Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like k141_4162_2 1278309.KB907099_gene2474 8.76e-129 370.0 COG2186@1|root,COG2186@2|Bacteria,1RC9V@1224|Proteobacteria,1S3E4@1236|Gammaproteobacteria,1XJE6@135619|Oceanospirillales 135619|Oceanospirillales K FCD - - - - - - - - - - - - FCD,GntR k141_4162_3 1278309.KB907099_gene2473 4.94e-50 165.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,1XHCX@135619|Oceanospirillales 135619|Oceanospirillales C Cysteine-rich domain - - - ko:K18928 - - - - ko00000 - - - CCG k141_20191_1 998674.ATTE01000001_gene2265 6.12e-34 122.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_20191_2 1247024.JRLH01000008_gene1466 1.06e-17 85.1 COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,1T63B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_4164_1 1280949.HAD_17002 3.3e-16 80.5 COG1975@1|root,COG2068@1|root,COG1975@2|Bacteria,COG2068@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria,43X8R@69657|Hyphomonadaceae 28211|Alphaproteobacteria O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - NTP_transf_3,XdhC_C,XdhC_CoxI k141_4165_1 195105.CN97_19620 7.67e-157 450.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2TSXN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane MA20_17625 - - - - - - - - - - - Urate_ox_N k141_4169_1 1134474.O59_004068 3.47e-31 124.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria N type VI secretion protein icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_4170_1 396588.Tgr7_2419 6.42e-62 198.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1WXAI@135613|Chromatiales 135613|Chromatiales H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_4170_2 710421.Mycch_1353 8.54e-29 103.0 COG1773@1|root,COG1773@2|Bacteria,2GR50@201174|Actinobacteria,23B70@1762|Mycobacteriaceae 201174|Actinobacteria C involved in the hydrocarbon hydroxylating system to convert conversion of dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase rubB - - - - - - - - - - - Rubredoxin k141_4170_3 395493.BegalDRAFT_2930 4.47e-16 74.7 COG0235@1|root,COG0235@2|Bacteria,1QAVF@1224|Proteobacteria,1RW3I@1236|Gammaproteobacteria,4628Z@72273|Thiotrichales 72273|Thiotrichales G PFAM Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_4171_1 225849.swp_1307 3.54e-56 181.0 COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria,2QBUK@267890|Shewanellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 k141_4173_1 1288826.MSNKSG1_17421 3.89e-157 449.0 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,465QR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - HDOD,tRNA_edit k141_20192_1 1479237.JMLY01000001_gene2446 1.3e-25 99.0 2ERWY@1|root,33JG3@2|Bacteria,1NIZY@1224|Proteobacteria,1SH96@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_20192_2 1288826.MSNKSG1_06428 1.05e-178 498.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,46AM0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0034641,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - iECUMN_1333.ECUMN_1592 adh_short_C2 k141_20192_3 1288826.MSNKSG1_06423 0.0 980.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,464JP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K13896 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_20192_4 1288826.MSNKSG1_06418 1.13e-249 684.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,464AH@72275|Alteromonadaceae 1236|Gammaproteobacteria P transport system, permease component yejE GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k141_20192_5 1288826.MSNKSG1_06413 2.88e-249 685.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,465NV@72275|Alteromonadaceae 1236|Gammaproteobacteria P transport system, permease component yejB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_20192_6 1288826.MSNKSG1_06408 0.0 1200.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,465WW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4166 ABC-type oligopeptide transport system, periplasmic component yejA GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_20192_7 1288826.MSNKSG1_06403 1.19e-64 211.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_4175_1 1278309.KB907099_gene2770 3.01e-103 319.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XHJ4@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_4175_2 207954.MED92_02943 3.57e-56 178.0 COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,1SCJZ@1236|Gammaproteobacteria,1XKZT@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - ko:K09790 - - - - ko00000 - - - DUF454 k141_4176_2 1288826.MSNKSG1_10333 2.7e-82 251.0 COG1462@1|root,COG1462@2|Bacteria,1NDU8@1224|Proteobacteria,1RPPY@1236|Gammaproteobacteria,467EW@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in formation of curli polymers csgG - - - - - - - - - - - CsgG k141_4180_1 367336.OM2255_03082 1.08e-52 179.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_20193_1 1120950.KB892819_gene7148 6.9e-69 219.0 COG2267@1|root,COG2267@2|Bacteria,2I2QH@201174|Actinobacteria 201174|Actinobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_20193_2 1042375.AFPL01000012_gene699 1.73e-61 192.0 COG0393@1|root,COG0393@2|Bacteria,1N109@1224|Proteobacteria,1S9H4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S excinuclease, ATPase subunit - - - - - - - - - - - - - k141_20193_3 1042375.AFPL01000012_gene700 8.53e-81 248.0 2DNSX@1|root,32YZ0@2|Bacteria,1NDSG@1224|Proteobacteria,1T3PH@1236|Gammaproteobacteria,46DB8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2 k141_4181_1 1476902.A0A067ZG57_9CAUD 1.03e-57 183.0 4QGER@10239|Viruses,4QW31@35237|dsDNA viruses no RNA stage,4QSJZ@28883|Caudovirales,4QJ2H@10662|Myoviridae 10662|Myoviridae S methyltransferase activity - - - - - - - - - - - - - k141_20194_1 472759.Nhal_0412 1.01e-129 407.0 COG0247@1|root,COG0277@1|root,COG0437@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0437@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_20197_1 90814.KL370891_gene363 4.78e-39 147.0 COG2197@1|root,COG3221@1|root,COG2197@2|Bacteria,COG3221@2|Bacteria,1QVNP@1224|Proteobacteria 1224|Proteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - 2.7.13.3 ko:K13040 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GerE,Phosphonate-bd k141_20199_2 765914.ThisiDRAFT_2583 3.02e-70 222.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria,1WWG9@135613|Chromatiales 135613|Chromatiales N MotA/TolQ/ExbB proton channel family - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_20200_1 1122947.FR7_1762 1.03e-27 111.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H20G@909932|Negativicutes 909932|Negativicutes H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_20202_1 686340.Metal_3349 3.38e-80 266.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_20204_2 1122201.AUAZ01000021_gene3178 1.44e-49 164.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,4650X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_20205_1 203122.Sde_1621 7.78e-57 186.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,4674R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_20205_2 1049564.TevJSym_al00350 1.02e-57 190.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1JA17@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_20206_1 215803.DB30_3583 1.52e-48 167.0 COG5434@1|root,COG5434@2|Bacteria,1MUGF@1224|Proteobacteria,43802@68525|delta/epsilon subdivisions,2X39Z@28221|Deltaproteobacteria,2YV1S@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - - k141_20207_2 1123518.ARWI01000001_gene651 4.15e-15 72.0 COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,4637D@72273|Thiotrichales 72273|Thiotrichales KNU Anti-sigma-28 factor FlgM - - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_2102_1 216594.MMAR_2186 5.47e-14 72.8 COG1670@1|root,COG1670@2|Bacteria,2ID0Y@201174|Actinobacteria,235WN@1762|Mycobacteriaceae 201174|Actinobacteria J N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_21611_1 690597.JH730961_gene4645 3.95e-37 133.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S2RR@1236|Gammaproteobacteria,1YP58@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase k141_21611_2 398767.Glov_1802 7.16e-94 280.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4308T@68525|delta/epsilon subdivisions,2X5CQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria V PFAM ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_6281_2 94624.Bpet1008 3.77e-18 84.3 2DTYR@1|root,33N91@2|Bacteria,1NIV1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_6281_3 1116472.MGMO_112c00130 4.1e-27 105.0 2DQ6U@1|root,3350B@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4393) - - - - - - - - - - - - DUF4393 k141_14649_1 936053.I1CKP3 1.85e-19 92.0 28N8N@1|root,2QUTZ@2759|Eukaryota,39XUZ@33154|Opisthokonta,3PDMC@4751|Fungi,1GXH4@112252|Fungi incertae sedis 4751|Fungi - - - - - - - - - - - - - - DDE_3,HTH_Tnp_Tc3_2 k141_9763_1 700598.Niako_0777 6.13e-21 95.9 COG0738@1|root,COG0738@2|Bacteria,4PN86@976|Bacteroidetes,1IWVH@117747|Sphingobacteriia 976|Bacteroidetes G major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 k141_11162_1 52598.EE36_12598 0.00015 47.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3ZV47@60136|Sulfitobacter 28211|Alphaproteobacteria V AcrB/AcrD/AcrF family ttgE - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_11162_2 1353528.DT23_01295 1.18e-86 274.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2XMJA@285107|Thioclava 28211|Alphaproteobacteria O Metal ABC transporter permease atm1 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_13945_1 1163408.UU9_14920 6.34e-46 158.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1X3A0@135614|Xanthomonadales 135614|Xanthomonadales S dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB k141_13945_2 1278309.KB907108_gene1600 1.53e-159 454.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XMZA@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_2,GST_N_2 k141_13945_3 460265.Mnod_5142 5.4e-41 140.0 COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,2U6MK@28211|Alphaproteobacteria,1JUWZ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM DoxX family protein - - - ko:K15977 - - - - ko00000 - - - DoxX k141_13945_4 207954.MED92_13418 6.85e-104 312.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1XJHN@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_13945_5 1278309.KB907108_gene1602 3.85e-05 44.7 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XR7Y@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase FAD-binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1 k141_705_1 981384.AEYW01000001_gene1531 1.53e-71 218.0 COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,4NC2B@97050|Ruegeria 28211|Alphaproteobacteria S Response regulator receiver domain protein - - - ko:K09958 - - - - ko00000 - - - DUF1348 k141_16036_1 485916.Dtox_3194 6.04e-51 168.0 COG3039@1|root,COG3039@2|Bacteria 2|Bacteria L Transposase - - - ko:K07481 - - - - ko00000 - - - DDE_Tnp_1,DUF772 k141_16036_2 768710.DesyoDRAFT_2480 6.47e-64 197.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,24BK2@186801|Clostridia,262Y3@186807|Peptococcaceae 186801|Clostridia L PFAM Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_8373_1 1288826.MSNKSG1_14077 0.0 1536.0 COG5001@1|root,COG5001@2|Bacteria,1PV95@1224|Proteobacteria,1RRN3@1236|Gammaproteobacteria,46D4V@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF k141_7679_1 396588.Tgr7_1125 1.48e-102 314.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1WXRW@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_17431_1 207954.MED92_14178 9.86e-151 441.0 COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RS4V@1236|Gammaproteobacteria,1XHIA@135619|Oceanospirillales 135619|Oceanospirillales T PFAM Extracellular solute-binding protein, family 3 - - - - - - - - - - - - HATPase_c,HisKA,SBP_bac_3 k141_6282_1 1122165.AUHS01000011_gene2548 1.14e-68 221.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1JC71@118969|Legionellales 118969|Legionellales D Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_15346_1 1237149.C900_03749 8.52e-61 207.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - OmpA,PD40 k141_12555_1 203122.Sde_0993 8.46e-152 456.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,464B1@72275|Alteromonadaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_11858_1 1266908.AQPB01000033_gene1683 7.06e-17 85.9 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4 k141_5581_1 1279015.KB908458_gene2601 4.23e-41 159.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - Cache_3-Cache_2,HAMP,MCPsignal,dCache_1 k141_5581_2 1116472.MGMO_66c00590 7.01e-57 186.0 COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,1XDKQ@135618|Methylococcales 135618|Methylococcales G pfkB family carbohydrate kinase - - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_18125_1 1123228.AUIH01000031_gene1705 1.77e-206 595.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1S1G2@1236|Gammaproteobacteria,1XN8X@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_18125_2 1123228.AUIH01000031_gene1706 1.32e-111 334.0 COG2358@1|root,COG2358@2|Bacteria,1Q6GH@1224|Proteobacteria,1RZ7Z@1236|Gammaproteobacteria,1XP0J@135619|Oceanospirillales 135619|Oceanospirillales S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_18125_3 981384.AEYW01000013_gene507 0.000141 51.2 COG0583@1|root,COG0583@2|Bacteria,1QU1H@1224|Proteobacteria,2U0TE@28211|Alphaproteobacteria,4ND30@97050|Ruegeria 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_18125_4 717774.Marme_3918 2.96e-179 521.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1XN54@135619|Oceanospirillales 135619|Oceanospirillales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_13255_1 1232683.ADIMK_3858 2.97e-87 269.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,1RQ5C@1236|Gammaproteobacteria,465H7@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 k141_13255_2 32042.PstZobell_16801 2.67e-09 57.8 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,1Z1VS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F xanthine xanQ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16345,ko:K16346 - - - - ko00000,ko02000 2.A.40,2.A.40.4.2,2.A.40.4.3 - iG2583_1286.G2583_3536 Xan_ur_permease k141_817_8 1288826.MSNKSG1_01778 3.33e-76 229.0 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,468QW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_817_9 1288826.MSNKSG1_01773 1.5e-219 607.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,467GK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,TPR_16 k141_817_10 1288826.MSNKSG1_01768 1.08e-140 398.0 COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,1S27B@1236|Gammaproteobacteria,4672C@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k141_21700_1 768671.ThimaDRAFT_4723 2.74e-25 97.1 COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,1SEZ9@1236|Gammaproteobacteria,1X23S@135613|Chromatiales 135613|Chromatiales CQ TIGRFAM Carboxysome peptide B - - - - - - - - - - - - EutN_CcmL k141_21700_2 314278.NB231_15173 2.88e-50 159.0 COG4576@1|root,COG4576@2|Bacteria,1MZNS@1224|Proteobacteria,1S9MK@1236|Gammaproteobacteria,1WYX9@135613|Chromatiales 135613|Chromatiales CQ PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml - - - - - - - - - - - - EutN_CcmL k141_3616_1 292415.Tbd_1193 3.43e-62 215.0 COG3852@1|root,COG4251@1|root,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VQJ3@28216|Betaproteobacteria,1KSXU@119069|Hydrogenophilales 119069|Hydrogenophilales T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 k141_2206_1 400668.Mmwyl1_3291 1.2e-81 252.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1XHTX@135619|Oceanospirillales 135619|Oceanospirillales M Phospholipase pldA - 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - PLA1 k141_18959_1 1125973.JNLC01000010_gene1341 2.13e-47 162.0 COG0702@1|root,COG0702@2|Bacteria,1PTZH@1224|Proteobacteria,2U0MV@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM NAD(P)H-binding - - - - - - - - - - - - Epimerase k141_19635_1 1123377.AUIV01000016_gene358 1.86e-23 98.2 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,1T1K8@1236|Gammaproteobacteria,1X3DZ@135614|Xanthomonadales 135614|Xanthomonadales I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_19635_2 314278.NB231_06041 1.58e-87 268.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales 135613|Chromatiales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_7808_1 266809.PM03_06995 1.14e-28 110.0 COG4960@1|root,COG4960@2|Bacteria,1RDMM@1224|Proteobacteria,2U7NB@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Flp pilus assembly protein protease CpaA - - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 k141_7808_2 1123247.AUIJ01000001_gene1708 3.53e-07 51.2 COG0457@1|root,COG0457@2|Bacteria,1MUW4@1224|Proteobacteria,2TRAE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19 k141_4977_1 472759.Nhal_3447 7.57e-37 137.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales 135613|Chromatiales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_1502_1 42565.FP66_14750 8.11e-138 403.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales 135619|Oceanospirillales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_11311_1 349124.Hhal_0051 4.54e-47 156.0 2CHIC@1|root,2ZNB5@2|Bacteria,1RBRG@1224|Proteobacteria,1S2NN@1236|Gammaproteobacteria,1WY5X@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2452) - - - - - - - - - - - - DUF2452 k141_11311_2 555778.Hneap_1885 4.53e-75 248.0 COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria,1X2B4@135613|Chromatiales 135613|Chromatiales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_11311_3 395494.Galf_1854 5.02e-23 94.7 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2WFRY@28216|Betaproteobacteria 28216|Betaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_8489_1 998674.ATTE01000001_gene1724 1.65e-65 205.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,460YE@72273|Thiotrichales 72273|Thiotrichales S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 k141_20373_1 2340.JV46_28890 4.54e-101 314.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_21701_1 439493.PB7211_763 4.18e-81 243.0 2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,4BRYT@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - k141_17530_1 1168067.JAGP01000001_gene744 1.7e-103 310.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,461ZM@72273|Thiotrichales 72273|Thiotrichales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_17530_2 83406.HDN1F_31730 8.22e-29 110.0 COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,1J6AC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis cheD GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_18246_2 305900.GV64_16975 6.28e-06 47.0 COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1S5D7@1236|Gammaproteobacteria,1XMDR@135619|Oceanospirillales 135619|Oceanospirillales E 5-carboxymethyl-2-hydroxymuconate isomerase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - - k141_819_1 34007.IT40_26525 3.04e-33 129.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2U2FB@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Oxidoreductase - - - - - - - - - - - - DAO k141_16850_1 765912.Thimo_1348 5.29e-62 210.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales 135613|Chromatiales M HAD-superfamily hydrolase, subfamily IIB - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_4987_3 631362.Thi970DRAFT_03191 2.06e-20 89.4 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXRF@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase family 2 - - 2.4.2.53 ko:K10012,ko:K20534 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8,4.D.2.1.9 GT2 - Glycos_transf_2 k141_839_1 1278309.KB907099_gene2748 1.01e-168 473.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XHRF@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter, ATP-binding protein - - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_839_2 1278309.KB907099_gene2749 1.32e-60 191.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XIQH@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter ATP-binding protein - - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k141_11322_1 187272.Mlg_2127 2.77e-91 289.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_12683_1 1278309.KB907099_gene2598 2.72e-81 246.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,1S5J1@1236|Gammaproteobacteria,1XJWS@135619|Oceanospirillales 135619|Oceanospirillales L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k141_14790_1 713587.THITH_06820 1.96e-92 281.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_14790_2 1283300.ATXB01000001_gene2262 0.0 886.0 COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1XENX@135618|Methylococcales 135618|Methylococcales M PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_10607_1 1278309.KB907103_gene1080 2.89e-162 474.0 COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,1T299@1236|Gammaproteobacteria,1XI0H@135619|Oceanospirillales 135619|Oceanospirillales T LapD/MoxY periplasmic domain - - - - - - - - - - - - EAL,GGDEF,LapD_MoxY_N k141_20385_1 1123518.ARWI01000001_gene556 1.05e-99 298.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,45ZQP@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_20385_2 1123261.AXDW01000001_gene1414 4.49e-16 77.4 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1X3M1@135614|Xanthomonadales 135614|Xanthomonadales I Fatty acid synthesis protein - - - - - - - - - - - - FA_synthesis k141_102_1 411684.HPDFL43_16556 1.4e-71 221.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2TTD0@28211|Alphaproteobacteria,43JUC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ related to short-chain alcohol - - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_102_2 391616.OA238_c14560 6.68e-64 211.0 COG1653@1|root,COG1653@2|Bacteria,1N1NW@1224|Proteobacteria,2U094@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_18973_1 876044.IMCC3088_635 3.11e-136 397.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MWNX@1224|Proteobacteria,1RQHG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Integrase catalytic - - - - - - - - - - - - HTH_23,LZ_Tnp_IS481,rve k141_18973_2 1304878.AUGD01000040_gene3272 2.17e-37 130.0 COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria,3JZI8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_13391_1 396588.Tgr7_1224 2.17e-51 175.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1WVV3@135613|Chromatiales 135613|Chromatiales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_13391_2 999141.GME_13853 9.95e-34 128.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1XIV2@135619|Oceanospirillales 135619|Oceanospirillales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_13391_3 765913.ThidrDRAFT_2734 1.61e-48 162.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1WWJ3@135613|Chromatiales 135613|Chromatiales N basal body rod protein - - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_4321_2 396588.Tgr7_2923 7.67e-81 248.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales 135613|Chromatiales S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_4321_3 1286106.MPL1_09190 3.6e-77 246.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,1RPSF@1236|Gammaproteobacteria,463VY@72273|Thiotrichales 72273|Thiotrichales G major facilitator superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_16868_1 1278309.KB907107_gene1754 4.52e-127 368.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XHJD@135619|Oceanospirillales 135619|Oceanospirillales T Two component signalling adaptor domain - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_16868_2 1278309.KB907107_gene1753 3.48e-144 410.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1XI9D@135619|Oceanospirillales 135619|Oceanospirillales NT MCP methyltransferase - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_7105_1 1040987.AZUY01000006_gene1835 2.44e-20 87.4 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,43K15@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_7105_2 318161.Sden_3167 9.21e-06 52.4 COG1514@1|root,COG1514@2|Bacteria,1QEB6@1224|Proteobacteria,1TAWU@1236|Gammaproteobacteria,2QCHE@267890|Shewanellaceae 1236|Gammaproteobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_1520_1 1288826.MSNKSG1_17586 9.52e-125 364.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,463YV@72275|Alteromonadaceae 1236|Gammaproteobacteria H Glutamate-1-semialdehyde aminotransferase hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 k141_1520_2 1288826.MSNKSG1_17591 7.68e-135 385.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,46740@72275|Alteromonadaceae 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_1520_3 1288826.MSNKSG1_17596 4.82e-175 488.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,4646B@72275|Alteromonadaceae 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_1520_4 1288826.MSNKSG1_17601 6.58e-56 176.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,467HW@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_5740_1 1288826.MSNKSG1_16281 0.0 1008.0 COG3127@1|root,COG3127@2|Bacteria,1QXGA@1224|Proteobacteria,1T3BG@1236|Gammaproteobacteria,467CX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_5740_2 1288826.MSNKSG1_16286 1.34e-141 406.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,466MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S secreted hydrolase attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_9172_1 1278309.KB907101_gene807 2.74e-110 319.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1XJF2@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_9172_2 1278309.KB907101_gene806 0.0 1114.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1XH7G@135619|Oceanospirillales 135619|Oceanospirillales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_9172_3 1278309.KB907101_gene805 6.74e-47 152.0 2EEU7@1|root,338MR@2|Bacteria,1NF6F@1224|Proteobacteria,1SFQ9@1236|Gammaproteobacteria,1XMC0@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9172_4 1278309.KB907101_gene804 1.17e-134 391.0 COG3782@1|root,COG3782@2|Bacteria,1MZ3U@1224|Proteobacteria,1S9NQ@1236|Gammaproteobacteria,1XM2Q@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1853) - - - ko:K09977 - - - - ko00000 - - - DUF1853 k141_16149_1 1278309.KB907108_gene1621 0.0 1170.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHS3@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg k141_16149_2 1278309.KB907108_gene1622 3.07e-283 805.0 COG4564@1|root,COG5002@1|root,COG4564@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1XRZS@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Response_reg k141_19649_1 688245.CtCNB1_1242 1.38e-14 73.2 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,4AA4C@80864|Comamonadaceae 28216|Betaproteobacteria S Predicted integral membrane protein (DUF2189) - - - - - - - - - - - - DUF2189 k141_19649_3 1121939.L861_20095 1.85e-90 276.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_12000_1 314271.RB2654_01215 3.24e-64 200.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2U70V@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - - - - - - - - - - Macro k141_12000_2 519989.ECTPHS_01799 1.4e-40 139.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1WYWV@135613|Chromatiales 135613|Chromatiales S Stringent starvation protein B - - - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_12000_3 1137799.GZ78_00070 7.94e-86 259.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XI89@135619|Oceanospirillales 135619|Oceanospirillales O Stringent starvation protein A sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_12000_4 1120999.JONM01000010_gene4072 5.11e-84 258.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,2KPTF@206351|Neisseriales 206351|Neisseriales C Cytochrome C1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_12000_5 292415.Tbd_1832 2.28e-224 629.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales 119069|Hydrogenophilales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_12000_6 870187.Thini_1052 1.56e-42 144.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,460ET@72273|Thiotrichales 72273|Thiotrichales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_21108_1 472759.Nhal_2405 4.92e-163 470.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales 135613|Chromatiales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_21108_2 998674.ATTE01000001_gene4300 1.81e-60 190.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,460T4@72273|Thiotrichales 72273|Thiotrichales J binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_21108_3 2340.JV46_07190 4.86e-25 94.4 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1J78G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L30p/L7e rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_21108_4 765910.MARPU_03805 4.67e-46 152.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1WX2D@135613|Chromatiales 135613|Chromatiales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_2924_1 1278309.KB907101_gene574 5.38e-189 534.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XIWX@135619|Oceanospirillales 135619|Oceanospirillales K membrane rbn-1 - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_2924_2 1191299.AJYX01000086_gene3101 4.79e-15 71.2 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XYDK@135623|Vibrionales 135623|Vibrionales C COG1254 Acylphosphatases acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase k141_2924_3 1278309.KB907101_gene576 5.28e-109 316.0 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1XJJU@135619|Oceanospirillales 135619|Oceanospirillales M Transglycosylase SLT domain - - - - - - - - - - - - SLT k141_2924_4 1278309.KB907101_gene577 1.01e-55 174.0 COG2329@1|root,COG2329@2|Bacteria,1MZKW@1224|Proteobacteria,1S9N8@1236|Gammaproteobacteria,1XKXM@135619|Oceanospirillales 135619|Oceanospirillales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_2924_5 1278309.KB907101_gene578 4.74e-108 318.0 COG3221@1|root,COG3221@2|Bacteria 2|Bacteria P organic phosphonate transport - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd,STAS_2 k141_2924_6 1278309.KB907101_gene579 5.29e-08 53.5 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XHB9@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_6395_2 103733.JNYO01000013_gene4292 1.8e-05 47.0 COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4E057@85010|Pseudonocardiales 201174|Actinobacteria G Glycosyl hydrolase family 1 - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 k141_10608_1 1298865.H978DRAFT_2544 0.000696 41.6 COG2248@1|root,COG2248@2|Bacteria,1MVZY@1224|Proteobacteria,1RPTC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative, 10TM heavy-metal exporter VP1164 - - - - - - - - - - - ArsP_2 k141_10608_2 391619.PGA1_c12100 1.02e-43 146.0 COG0789@1|root,COG0789@2|Bacteria,1RH2P@1224|Proteobacteria,2U9RX@28211|Alphaproteobacteria,34FPE@302485|Phaeobacter 28211|Alphaproteobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_10608_3 292414.TM1040_1556 1.97e-06 47.4 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2U98M@28211|Alphaproteobacteria,4NC9G@97050|Ruegeria 28211|Alphaproteobacteria K Transcriptional regulator, merR family - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_9872_1 1278309.KB907102_gene192 4.58e-124 363.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,1XI5J@135619|Oceanospirillales 135619|Oceanospirillales M Domain of unknown function (DUF3524) - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_16869_1 1049564.TevJSym_ah00650 4.35e-86 276.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1J5H0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Type I restriction-modification system - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_8500_1 1415756.JQMY01000001_gene1832 1.31e-125 370.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2PD5V@252301|Oceanicola 28211|Alphaproteobacteria C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17553_1 1121022.ABENE_11090 1.16e-23 100.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2TRJP@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Long-chain fatty acid transport protein - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_17553_2 765912.Thimo_2637 2.35e-93 274.0 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,1RRM7@1236|Gammaproteobacteria,1X23M@135613|Chromatiales 135613|Chromatiales S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_17553_3 768671.ThimaDRAFT_2070 3.33e-11 66.2 COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,1S69P@1236|Gammaproteobacteria,1WX67@135613|Chromatiales 135613|Chromatiales K cyclic nucleotide-binding - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_5840_43 391587.KAOT1_13682 1.57e-69 224.0 COG4639@1|root,COG4639@2|Bacteria,4NIPE@976|Bacteroidetes 976|Bacteroidetes S AAA domain - - - - - - - - - - - - AAA_33,Acid_phosphat_B k141_5840_47 1458716.W8FTA2_9CAUD 3.26e-139 422.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k141_5840_51 160488.PP_2273 1.07e-54 201.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,1SJP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k141_5840_55 1114179.I2FLR4_9CAUD 3.27e-28 117.0 4QFN3@10239|Viruses,4QZSZ@35237|dsDNA viruses no RNA stage,4QQ4M@28883|Caudovirales,4QNXC@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k141_5840_58 1235661.K0IK58_9CAUD 2.56e-72 228.0 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k141_5840_59 194699.Q774Z7_BPBPP 1.27e-19 84.0 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae 10744|Podoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k141_5125_1 96561.Dole_3250 1.75e-65 215.0 COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1,DUF772 k141_8628_1 870187.Thini_3115 7.75e-65 208.0 COG0457@1|root,COG0457@2|Bacteria,1R85G@1224|Proteobacteria,1S0MD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_3759_1 400668.Mmwyl1_3039 6.91e-52 170.0 COG3531@1|root,COG3531@2|Bacteria,1RA76@1224|Proteobacteria,1RSJ2@1236|Gammaproteobacteria,1XS76@135619|Oceanospirillales 135619|Oceanospirillales O Protein-disulfide isomerase - - - ko:K07396 - - - - ko00000 - - - DSBA k141_21224_1 565045.NOR51B_1193 3.5e-58 194.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21224_2 685782.O99_00831 2.02e-05 48.5 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,48TIP@772|Bartonellaceae 28211|Alphaproteobacteria V Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides macB - - ko:K05685 ko02010,map02010 M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.122.1,3.A.1.122.12 - - ABC_tran,FtsX,MacB_PCD k141_13498_1 1123401.JHYQ01000015_gene1405 2.94e-78 255.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales 72273|Thiotrichales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_953_1 1278309.KB907101_gene444 1.36e-230 650.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XH9G@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter - - - ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_11437_1 371731.Rsw2DRAFT_1516 3.99e-94 286.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,1FBAB@1060|Rhodobacter 28211|Alphaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_7235_1 1121479.AUBS01000002_gene3688 2.6e-99 294.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_3066_1 743721.Psesu_1388 1.7e-14 75.1 COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1X4RV@135614|Xanthomonadales 135614|Xanthomonadales M UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase rfb303 - - - - - - - - - - - Glycos_transf_4 k141_3066_2 1500893.JQNB01000001_gene2275 1.83e-47 161.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1X361@135614|Xanthomonadales 135614|Xanthomonadales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_7 k141_19118_1 686340.Metal_3509 2.44e-53 186.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XDU6@135618|Methylococcales 135618|Methylococcales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_15603_1 105559.Nwat_1944 1.93e-90 275.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales 135613|Chromatiales HJ TIGRFAM alpha-L-glutamate ligase-like protein - - - - - - - - - - - - ATPgrasp_ST k141_17711_1 520709.F985_00662 4.37e-68 217.0 COG2267@1|root,COG2267@2|Bacteria,1RJ4X@1224|Proteobacteria,1SG4Q@1236|Gammaproteobacteria,3NM6Y@468|Moraxellaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_14198_1 1121943.KB899992_gene2277 6.23e-94 288.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XI6I@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_7965_1 1278309.KB907102_gene6 3.32e-55 185.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XH4N@135619|Oceanospirillales 135619|Oceanospirillales J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_9286_2 1288826.MSNKSG1_10098 2.99e-96 281.0 COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria 1224|Proteobacteria C maturation vhtD - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI k141_9286_3 1288826.MSNKSG1_10093 2.3e-51 162.0 2DCC8@1|root,2ZDND@2|Bacteria 2|Bacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - - - - - - - - - - HypA k141_9971_1 1288826.MSNKSG1_09153 8.42e-234 650.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_9971_2 1288826.MSNKSG1_09158 1.05e-123 353.0 COG2888@1|root,COG2888@2|Bacteria,1N3WA@1224|Proteobacteria,1S98T@1236|Gammaproteobacteria,46983@72275|Alteromonadaceae 1236|Gammaproteobacteria J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_9971_3 1288826.MSNKSG1_09163 0.0 1725.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,464DK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_954_2 1121403.AUCV01000004_gene2046 3.27e-37 138.0 COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,42S2Q@68525|delta/epsilon subdivisions,2WNSG@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Surface antigen - - - - - - - - - - - - Bac_surface_Ag k141_5126_1 1278309.KB907104_gene951 2.96e-52 169.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XK48@135619|Oceanospirillales 135619|Oceanospirillales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_5126_2 190486.XAC0222 0.000214 42.7 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1X2XQ@135614|Xanthomonadales 135614|Xanthomonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_18392_1 2340.JV46_09960 1.38e-94 289.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_6485_1 1300345.LF41_3107 3.79e-55 178.0 COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,1X4Z5@135614|Xanthomonadales 135614|Xanthomonadales S UPF0114 protein - - - - - - - - - - - - UPF0114 k141_6485_2 998674.ATTE01000001_gene4229 7.51e-43 145.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,461V2@72273|Thiotrichales 72273|Thiotrichales J Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - MTS k141_7236_1 653733.Selin_1726 2.65e-08 60.8 COG2202@1|root,COG3290@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K13040 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3365,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k141_20528_1 43989.cce_0530 1.29e-14 69.7 COG2954@1|root,COG2954@2|Bacteria,1G5NQ@1117|Cyanobacteria,3KI11@43988|Cyanothece 1117|Cyanobacteria S Adenylate cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CYTH k141_20528_2 1026882.MAMP_02636 8.69e-69 213.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,460TV@72273|Thiotrichales 72273|Thiotrichales S PFAM L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_20528_3 519989.ECTPHS_12998 1.66e-28 111.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1WXR0@135613|Chromatiales 135613|Chromatiales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_19119_1 713586.KB900536_gene1098 1.58e-60 198.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_7966_1 1443111.JASG01000004_gene3597 1.54e-104 327.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,3ZUWA@60136|Sulfitobacter 28211|Alphaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_1680_1 272943.RSP_4017 8.67e-84 265.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,1FCG8@1060|Rhodobacter 28211|Alphaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_10742_1 472759.Nhal_3609 3.66e-89 270.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_13499_1 1403819.BATR01000007_gene237 6.14e-79 252.0 COG2133@1|root,COG2133@2|Bacteria,46V55@74201|Verrucomicrobia,2IVGJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_955_1 1278309.KB907101_gene521 9.81e-42 149.0 COG3064@1|root,COG3064@2|Bacteria,1RINZ@1224|Proteobacteria,1S7TN@1236|Gammaproteobacteria,1XM41@135619|Oceanospirillales 135619|Oceanospirillales M Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 k141_955_2 1278309.KB907101_gene520 1.27e-25 105.0 28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria,1XJA1@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - DUF4129 k141_19767_1 713586.KB900536_gene70 5.29e-211 593.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1WWEG@135613|Chromatiales 135613|Chromatiales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_16258_1 1116472.MGMO_41c00520 7.98e-08 53.9 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XE2C@135618|Methylococcales 135618|Methylococcales KL HELICc2 - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2 k141_6486_1 522306.CAP2UW1_2267 6.1e-86 265.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria 28216|Betaproteobacteria G sorbosone dehydrogenase - - - - - - - - - - - - GSDH,SGL k141_3068_1 1286631.X805_18410 9.28e-55 192.0 COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria 28216|Betaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_20529_2 1056820.KB900651_gene3161 1.65e-39 139.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,2PMX6@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Pfam:DUF328 yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_19120_1 204536.SULAZ_1315 2.9e-12 69.3 COG0517@1|root,COG2199@1|root,COG2905@1|root,COG0517@2|Bacteria,COG2905@2|Bacteria,COG3706@2|Bacteria,2G47E@200783|Aquificae 200783|Aquificae T GGDEF domain - - - - - - - - - - - - CBS,GGDEF k141_19120_2 1340493.JNIF01000003_gene1281 2.31e-22 94.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity M1-798 - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5,Rhodanese k141_269_1 396588.Tgr7_2461 4.34e-87 275.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_2335_1 1288826.MSNKSG1_10868 2.34e-223 618.0 COG1018@1|root,COG1018@2|Bacteria,1RESB@1224|Proteobacteria,1SYC4@1236|Gammaproteobacteria,467XJ@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1 k141_2335_2 1288826.MSNKSG1_10873 7.94e-273 745.0 COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria,1RQCX@1236|Gammaproteobacteria,4669N@72275|Alteromonadaceae 1236|Gammaproteobacteria I fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_2335_3 1288826.MSNKSG1_10878 2.57e-97 283.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,467Q8@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator nsrR - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_17722_1 488538.SAR116_0791 1.61e-24 107.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2U0E0@28211|Alphaproteobacteria,4BQRH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V Beta-lactamase nylB - - - - - - - - - - - Beta-lactamase k141_9990_1 522306.CAP2UW1_2030 8.41e-12 68.6 COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria 28216|Betaproteobacteria S ribonuclease BN - - - - - - - - - - - - Virul_fac_BrkB k141_9990_2 580332.Slit_2526 4.77e-110 331.0 COG0387@1|root,COG0387@2|Bacteria,1MWD8@1224|Proteobacteria,2VJQM@28216|Betaproteobacteria,44V5W@713636|Nitrosomonadales 28216|Betaproteobacteria P PFAM sodium calcium exchanger membrane region - - - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex k141_20543_1 264730.PSPPH_3413 3.13e-45 159.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1Z76K@136849|Pseudomonas syringae group 1236|Gammaproteobacteria T chemotaxis cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_9303_1 1121405.dsmv_0504 3.92e-13 72.8 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N5C@68525|delta/epsilon subdivisions,2WM18@28221|Deltaproteobacteria,2MIV1@213118|Desulfobacterales 28221|Deltaproteobacteria T PFAM ATP-binding region ATPase domain protein - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg k141_9303_2 765912.Thimo_1242 3.44e-80 253.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21236_1 1298858.AUEL01000018_gene2920 8.92e-52 173.0 COG1309@1|root,COG1309@2|Bacteria,1N4J6@1224|Proteobacteria,2UIZP@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_C,TetR_N k141_15614_1 1288826.MSNKSG1_10813 4.99e-178 502.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,469RP@72275|Alteromonadaceae 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_974_1 1278309.KB907109_gene3298 5.3e-21 89.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria,1XHSX@135619|Oceanospirillales 135619|Oceanospirillales F Glutamine amidotransferase class-I - - - - - - - - - - - - GATase k141_974_2 1278309.KB907109_gene3297 1.9e-136 395.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XIRD@135619|Oceanospirillales 135619|Oceanospirillales CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_13510_1 1288826.MSNKSG1_01658 1.99e-97 313.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1T3BM@1236|Gammaproteobacteria,469XC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631,EAL,GGDEF k141_19130_1 1304883.KI912532_gene416 8.59e-33 132.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KUPC@206389|Rhodocyclales 206389|Rhodocyclales T COG2202 FOG PAS PAC domain - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3,TarH k141_10883_2 765911.Thivi_2812 3.83e-13 68.9 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WWUY@135613|Chromatiales 135613|Chromatiales L reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k141_17107_1 1278309.KB907111_gene3371 6.43e-214 619.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,1XIUF@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the peptidase M16 family - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_21342_1 159087.Daro_0110 9.39e-32 120.0 COG0745@1|root,COG0745@2|Bacteria,1R7VB@1224|Proteobacteria,2VI0D@28216|Betaproteobacteria,2KVAH@206389|Rhodocyclales 206389|Rhodocyclales T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2,Response_reg k141_21342_2 580332.Slit_1029 1.61e-22 107.0 COG1086@1|root,COG2199@1|root,COG5000@1|root,COG1086@2|Bacteria,COG2199@2|Bacteria,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.7.7,2.7.8.33,2.7.8.35 ko:K02342,ko:K02851 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378,R08856 RC00002,RC02795 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03032,ko03400 - - - CoA_binding_3,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9,RNase_T,SpoIIE k141_5956_1 1443111.JASG01000004_gene1357 5.57e-28 109.0 COG0524@1|root,COG0524@2|Bacteria,1MXSY@1224|Proteobacteria,2TR08@28211|Alphaproteobacteria,3ZVPW@60136|Sulfitobacter 28211|Alphaproteobacteria G pfkB family carbohydrate kinase psuK - 2.7.1.83 ko:K16328 ko00240,map00240 - R03315 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HTH_24,PfkB k141_5956_2 1042326.AZNV01000024_gene2391 3.03e-15 73.6 COG1309@1|root,COG1309@2|Bacteria,1RC7C@1224|Proteobacteria,2U5YR@28211|Alphaproteobacteria,4B8MP@82115|Rhizobiaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_11553_1 93220.LV28_08785 1.12e-31 121.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1JZMG@119060|Burkholderiaceae 28216|Betaproteobacteria C oxidoreductase FAD NAD(P)-binding domain protein ascD - 1.17.1.1 ko:K00523,ko:K18248 ko00520,ko00627,ko01120,map00520,map00627,map01120 M00637 R00823,R00825,R03391,R03392 RC00192,RC00230 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1,Rieske k141_11553_2 983545.Glaag_0240 7.4e-17 84.0 COG1835@1|root,COG1835@2|Bacteria 2|Bacteria I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 k141_15027_1 1396858.Q666_13880 1e-174 512.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_3862_1 43354.JOIJ01000012_gene951 5.9e-36 135.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4E00A@85010|Pseudonocardiales 201174|Actinobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_3862_2 258594.RPA4566 2.83e-23 98.2 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2TQQQ@28211|Alphaproteobacteria,3JQN3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_13658_1 1121479.AUBS01000017_gene1732 1.1e-86 266.0 COG1539@1|root,COG1539@2|Bacteria,1MY5Q@1224|Proteobacteria,2TRVX@28211|Alphaproteobacteria 28211|Alphaproteobacteria H dihydroneopterin aldolase folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - 4HFCP_synth,FolB k141_6630_1 1122201.AUAZ01000023_gene2989 0.0 1634.0 COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1RY2M@1236|Gammaproteobacteria,46772@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_3 k141_6630_2 443152.MDG893_02680 1.07e-53 175.0 28Q1W@1|root,2ZCK4@2|Bacteria,1RDIF@1224|Proteobacteria,1S4Y2@1236|Gammaproteobacteria,467SB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17850_1 225849.swp_0846 1.47e-34 134.0 COG3713@1|root,COG3713@2|Bacteria,1MXXC@1224|Proteobacteria,1RYNJ@1236|Gammaproteobacteria,2QA3G@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM MltA-interacting MipA family protein - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_3227_1 998674.ATTE01000001_gene2013 5.74e-70 231.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,45ZZJ@72273|Thiotrichales 72273|Thiotrichales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_10884_1 105559.Nwat_2718 1.02e-77 242.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_7367_1 2340.JV46_06000 9.42e-46 154.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1J6DD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C k141_19272_1 113395.AXAI01000013_gene6838 1.36e-65 222.0 COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,3JRTU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_5289_1 1123518.ARWI01000001_gene1808 2.6e-19 84.3 COG1416@1|root,COG1416@2|Bacteria,1N5DH@1224|Proteobacteria,1SF5J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_17108_1 545264.KB898754_gene1802 9.76e-43 149.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_17108_2 1216007.AOPM01000052_gene2188 4.01e-23 97.4 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,2Q2EA@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E asparagine synthase (glutamine-hydrolyzing) asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_20641_1 867900.Celly_1243 5.77e-15 83.2 COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,1F8ND@104264|Cellulophaga 976|Bacteroidetes M COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein - - - - - - - - - - - - OMP_b-brl,OmpA,TSP_3 k141_8747_1 1116472.MGMO_103c00140 5.28e-48 165.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,1T3H9@1236|Gammaproteobacteria,1XDWD@135618|Methylococcales 135618|Methylococcales H Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_5966_3 1122201.AUAZ01000005_gene548 9.52e-52 193.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,4650Y@72275|Alteromonadaceae 1236|Gammaproteobacteria NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_3876_1 716928.AJQT01000064_gene5333 5.48e-44 149.0 COG0457@1|root,COG0457@2|Bacteria,1QY6Q@1224|Proteobacteria,2TXID@28211|Alphaproteobacteria,4BD5G@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 k141_438_2 998674.ATTE01000001_gene239 1.92e-70 227.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,460KI@72273|Thiotrichales 72273|Thiotrichales P Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085) - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_1141_2 1278309.KB907104_gene974 2.04e-93 276.0 COG3613@1|root,COG3613@2|Bacteria,1N0AK@1224|Proteobacteria,1S88V@1236|Gammaproteobacteria,1XMFB@135619|Oceanospirillales 135619|Oceanospirillales F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr k141_1141_3 1278309.KB907104_gene975 9.41e-49 156.0 2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,1SCYA@1236|Gammaproteobacteria,1XM1Y@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF5062) - - - - - - - - - - - - DUF5062 k141_13679_1 717773.Thicy_0462 6.88e-22 87.4 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,46133@72273|Thiotrichales 72273|Thiotrichales J Sigma 54 modulation protein yhbH - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_13679_2 1232683.ADIMK_2787 6.41e-150 437.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_10152_1 252305.OB2597_11306 2.57e-95 309.0 28H8H@1|root,2Z7KE@2|Bacteria,1MV77@1224|Proteobacteria,2TSVV@28211|Alphaproteobacteria,2PCGD@252301|Oceanicola 28211|Alphaproteobacteria S Aerotolerance regulator N-terminal MA20_44655 - - - - - - - - - - - BatA,DUF4159 k141_17121_1 717772.THIAE_03185 4.1e-59 197.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,45ZY0@72273|Thiotrichales 72273|Thiotrichales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_10909_1 1255043.TVNIR_2716 4.75e-23 97.8 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_10909_2 1123368.AUIS01000019_gene1219 6.26e-43 159.0 COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 k141_19290_1 472759.Nhal_3350 3.98e-63 211.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1S0CW@1236|Gammaproteobacteria,1X2DN@135613|Chromatiales 135613|Chromatiales NT CheB methylesterase - - - ko:K06597 ko02020,map02020 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheB_methylest k141_19290_2 1117647.M5M_11225 1.21e-08 55.8 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1J6YN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT CheW-like domain chpC - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_18516_2 1265505.ATUG01000002_gene1682 1.02e-27 112.0 COG3221@1|root,COG3221@2|Bacteria,1QVNP@1224|Proteobacteria,42S28@68525|delta/epsilon subdivisions,2WP33@28221|Deltaproteobacteria,2MN7E@213118|Desulfobacterales 28221|Deltaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - - - - - - - - - - Phosphonate-bd k141_14318_1 1122599.AUGR01000025_gene1456 4.89e-18 82.8 COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,1T299@1236|Gammaproteobacteria,1XI0H@135619|Oceanospirillales 135619|Oceanospirillales T LapD/MoxY periplasmic domain - - - - - - - - - - - - EAL,GGDEF,LapD_MoxY_N k141_14318_2 1278309.KB907103_gene1081 1.02e-116 336.0 COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,1XJ4Z@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial transglutaminase-like cysteine proteinase BTLCP - - - - - - - - - - - - Peptidase_C93 k141_15045_1 519989.ECTPHS_03894 1.49e-53 174.0 COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,1SBYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Heptaprenyl diphosphate synthase component I - - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I k141_5306_2 744985.HIMB59_00006520 3.69e-36 131.0 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2TTN8@28211|Alphaproteobacteria,4BRAZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G ATPases associated with a variety of cellular activities - - - ko:K10554 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - ABC_tran k141_19906_1 331869.BAL199_05294 8.8e-117 363.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2U1PA@28211|Alphaproteobacteria,4BPCU@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain psrA - 1.8.5.6 ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_439_1 439235.Dalk_3497 8.53e-22 96.3 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1QW1M@1224|Proteobacteria 1224|Proteobacteria T SMART PAS domain containing protein - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - - k141_12305_1 1123400.KB904758_gene2234 1.79e-51 172.0 COG0242@1|root,COG0645@1|root,COG0242@2|Bacteria,COG0645@2|Bacteria,1R9XK@1224|Proteobacteria,1S672@1236|Gammaproteobacteria,462KT@72273|Thiotrichales 72273|Thiotrichales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_20651_1 1278309.KB907100_gene1839 2.32e-83 254.0 2BZVX@1|root,32R5V@2|Bacteria,1RKXP@1224|Proteobacteria,1S6T6@1236|Gammaproteobacteria,1XKCA@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20651_2 1278309.KB907100_gene1838 1.13e-27 105.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1XMBY@135619|Oceanospirillales 135619|Oceanospirillales K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_17122_2 1366046.HIMB11_00857 3.87e-35 122.0 COG3255@1|root,COG3255@2|Bacteria,1N0RD@1224|Proteobacteria,2UBXK@28211|Alphaproteobacteria,3ZHTN@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria I sterol carrier protein - - - - - - - - - - - - SCP2 k141_15787_1 697282.Mettu_2538 3.64e-71 223.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XDS5@135618|Methylococcales 135618|Methylococcales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_13680_1 1188256.BASI01000001_gene787 8.5e-53 173.0 COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,3FDCZ@34008|Rhodovulum 28211|Alphaproteobacteria J Protein of unknown function (DUF448) MA20_23920 - - ko:K07742 - - - - ko00000 - - - DUF448,Ribosomal_L7Ae k141_13680_2 367336.OM2255_09336 1.1e-16 80.9 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_4629_1 311402.Avi_0818 4.3e-77 245.0 COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,4BB3F@82115|Rhizobiaceae 28211|Alphaproteobacteria K transcriptional - - - ko:K07110 - - - - ko00000,ko03000 - - - DUF2083,HTH_3,HTH_31,Peptidase_M78 k141_1142_1 1167006.UWK_00327 1.84e-61 202.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales 28221|Deltaproteobacteria P Ammonium Transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_1142_2 999541.bgla_1g35560 7.8e-16 77.4 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1K0BN@119060|Burkholderiaceae 28216|Betaproteobacteria P Ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_5968_1 472759.Nhal_0146 6.68e-110 332.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales 135613|Chromatiales K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_19291_1 391624.OIHEL45_01415 5.02e-12 65.9 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,2TSSX@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA - 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_19291_2 1231190.NA8A_11630 2.02e-23 99.0 COG4658@1|root,COG4658@2|Bacteria,1PWBH@1224|Proteobacteria,2V6AM@28211|Alphaproteobacteria,43KT8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U Belongs to the NqrB RnfD family - - - - - - - - - - - - NQR2_RnfD_RnfE k141_13000_1 1278309.KB907099_gene2512 7.49e-07 50.8 COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,1RP83@1236|Gammaproteobacteria,1XIK7@135619|Oceanospirillales 135619|Oceanospirillales L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C k141_13000_2 1278309.KB907099_gene2513 0.0 1712.0 COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1XI3A@135619|Oceanospirillales 135619|Oceanospirillales L Putative exonuclease SbcCD, C subunit sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,SbcCD_C k141_22030_1 105559.Nwat_1094 7.02e-176 504.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales 135613|Chromatiales T SMART Nucleotide binding protein, PINc - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_10910_2 1178482.BJB45_03740 1e-58 192.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XHV3@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_10154_1 1278309.KB907100_gene2100 2.44e-154 444.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1XH3F@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_17123_1 754476.Q7A_609 3.72e-06 48.1 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,460Q1@72273|Thiotrichales 72273|Thiotrichales E D,D-heptose 1,7-bisphosphate phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like k141_17123_2 754476.Q7A_610 1.34e-59 193.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales 72273|Thiotrichales I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_12306_1 1282876.BAOK01000001_gene962 6.82e-67 219.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria,4BRFG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Conserved region in glutamate synthase - - - - - - - - - - - - Glu_synthase k141_8159_1 380703.AHA_2188 5.39e-50 189.0 COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Y3V7@135624|Aeromonadales 135624|Aeromonadales T Hpt domain - - - - - - - - - - - - DUF4118,HATPase_c,HisKA,Hpt,PAS_3,Response_reg k141_8159_3 675814.VIC_004972 1.53e-22 98.2 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1T4TS@1236|Gammaproteobacteria,1Y38G@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_13681_1 1288826.MSNKSG1_15871 7.92e-112 327.0 COG0834@1|root,COG0834@2|Bacteria,1RJRT@1224|Proteobacteria,1S7XT@1236|Gammaproteobacteria,46DGT@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_6645_1 379731.PST_2817 1.71e-11 63.2 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1Z2V8@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit1 - - - - - - - - - - - HIT k141_16418_1 395493.BegalDRAFT_1966 9.06e-66 206.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,460M5@72273|Thiotrichales 72273|Thiotrichales S Bacterial transferase hexapeptide - - - - - - - - - - - - Hexapep k141_16418_2 936455.KI421499_gene2112 6.83e-61 195.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,3JVI7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase gstch10 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_7387_1 1266908.AQPB01000060_gene176 1.44e-106 323.0 COG0843@1|root,COG0843@2|Bacteria,1QDZV@1224|Proteobacteria,1RYXY@1236|Gammaproteobacteria,1X0EJ@135613|Chromatiales 135613|Chromatiales C PFAM cytochrome c oxidase subunit I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_10911_1 153721.MYP_4146 9.82e-100 320.0 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_4630_1 391595.RLO149_c040760 4.52e-84 250.0 COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,2P32A@2433|Roseobacter 28211|Alphaproteobacteria S Carbon monoxide dehydrogenase subunit G (CoxG) - - - ko:K09386 - - - - ko00000 - - - COXG k141_18030_2 765912.Thimo_0391 8.7e-158 451.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria,1WXHU@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_18030_3 1121937.AUHJ01000013_gene841 1.05e-11 61.2 28YNN@1|root,2ZKGA@2|Bacteria,1P4W0@1224|Proteobacteria,1SUQ0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4771_1 1033734.CAET01000046_gene605 7.6e-31 125.0 COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,4HBIJ@91061|Bacilli,1ZB52@1386|Bacillus 91061|Bacilli C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_12454_1 522373.Smlt0629 5.19e-85 265.0 COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,1S0R5@1236|Gammaproteobacteria,1X5SI@135614|Xanthomonadales 135614|Xanthomonadales H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_21497_1 631362.Thi970DRAFT_00780 1.29e-140 415.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1WW58@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_20008_1 1123278.KB893580_gene892 3.75e-22 98.6 COG0500@1|root,COG2226@2|Bacteria,4NIN6@976|Bacteroidetes,47JAJ@768503|Cytophagia 976|Bacteroidetes Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25,Ubie_methyltran k141_1281_1 1232683.ADIMK_3919 2.77e-101 308.0 COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria 1224|Proteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_1281_2 1232683.ADIMK_2338 2.63e-08 53.9 28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S49D@1236|Gammaproteobacteria,469ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13136_2 1288826.MSNKSG1_07923 9.69e-07 53.5 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_8267_1 519989.ECTPHS_04618 1.07e-73 234.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1WWSE@135613|Chromatiales 135613|Chromatiales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_8267_2 440512.C211_20463 1.38e-46 158.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria N this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine motC - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_8852_1 1095769.CAHF01000011_gene2009 1.06e-75 234.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2VPF9@28216|Betaproteobacteria 28216|Betaproteobacteria S Short-chain dehydrogenase reductase (SDR) - - - - - - - - - - - - adh_short k141_18031_1 1268237.G114_00560 6.96e-91 270.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1Y59G@135624|Aeromonadales 135624|Aeromonadales L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn - - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_18674_1 1122139.KB907904_gene818 3.55e-71 223.0 COG1682@1|root,COG1682@2|Bacteria,1MUTE@1224|Proteobacteria,1RZ4T@1236|Gammaproteobacteria,1XKQZ@135619|Oceanospirillales 135619|Oceanospirillales GM ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane k141_18674_2 1278309.KB907100_gene1790 1.58e-56 181.0 COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1XJJJ@135619|Oceanospirillales 135619|Oceanospirillales GM ABC transporter ATP-binding protein - - 3.6.3.38 ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.103 - - ABC_tran k141_13137_1 1278309.KB907107_gene1730 5.17e-64 218.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales 135619|Oceanospirillales T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_13137_2 1122137.AQXF01000001_gene2744 3.78e-11 65.1 COG3591@1|root,COG3591@2|Bacteria,1MXUN@1224|Proteobacteria,2TT3R@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG3591 V8-like Glu-specific endopeptidase - - - ko:K04775 - - - - ko00000,ko01000,ko01002 - - - Trypsin,Trypsin_2 k141_13834_1 936136.ARRT01000006_gene4053 1.98e-48 169.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,2TVXP@28211|Alphaproteobacteria,4B89M@82115|Rhizobiaceae 28211|Alphaproteobacteria P ABC-type Zn2 transport system, periplasmic component surface adhesin znuA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_15905_2 1123514.KB905899_gene480 3.81e-73 262.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,460BU@72273|Thiotrichales 72273|Thiotrichales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3 k141_5459_2 1266914.ATUK01000011_gene2525 3.54e-24 99.4 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SARP@1236|Gammaproteobacteria 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_13138_1 1117647.M5M_00720 2.11e-77 240.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1J4MQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_22158_2 1278309.KB907100_gene1845 1.27e-131 373.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1XI52@135619|Oceanospirillales 135619|Oceanospirillales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_22158_3 1278309.KB907100_gene1846 5.28e-94 282.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1XHX0@135619|Oceanospirillales 135619|Oceanospirillales C lysine 2,3-aminomutase epmB - - ko:K19810 - - - - ko00000,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM k141_1950_1 1300345.LF41_3107 1.6e-55 181.0 COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,1X4Z5@135614|Xanthomonadales 135614|Xanthomonadales S UPF0114 protein - - - - - - - - - - - - UPF0114 k141_1950_2 754476.Q7A_526 5.82e-48 155.0 2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,462XP@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_1950_3 1286106.MPL1_02016 8.49e-34 121.0 2EFAS@1|root,3393N@2|Bacteria,1NDQN@1224|Proteobacteria,1SSBD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1950_4 395493.BegalDRAFT_0699 2.2e-139 418.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,46214@72273|Thiotrichales 72273|Thiotrichales H UbiA prenyltransferase family - - - - - - - - - - - - HAD,UbiA k141_1950_5 483219.LILAB_13360 2.37e-74 238.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,42MN7@68525|delta/epsilon subdivisions,2WIVK@28221|Deltaproteobacteria,2YYIN@29|Myxococcales 28221|Deltaproteobacteria C FAD binding domain - - - - - - - - - - - - FAD_binding_4 k141_2609_1 666509.RCA23_c30040 1.31e-39 146.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_2609_2 1305735.JAFT01000004_gene217 9.63e-119 352.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,2PCBT@252301|Oceanicola 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP,TAT_signal k141_2609_3 1305735.JAFT01000004_gene216 7.94e-191 550.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2V8HS@28211|Alphaproteobacteria,2PEZU@252301|Oceanicola 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_11685_1 585506.HMPREF0877_1245 1.69e-19 88.2 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,4AWWZ@81850|Leuconostocaceae 91061|Bacilli G 6-phosphogluconate dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_11685_2 179408.Osc7112_4872 1.2e-46 155.0 COG1051@1|root,COG1051@2|Bacteria,1G513@1117|Cyanobacteria,1HAIP@1150|Oscillatoriales 1117|Cyanobacteria F Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_11685_3 1169154.KB897782_gene4719 1.72e-46 153.0 COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria 201174|Actinobacteria CO Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin k141_11685_4 572477.Alvin_0409 1.26e-51 174.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_13835_1 1353537.TP2_15280 9.54e-89 270.0 COG1879@1|root,COG1879@2|Bacteria,1PJU5@1224|Proteobacteria,2V9UW@28211|Alphaproteobacteria,2XNUK@285107|Thioclava 28211|Alphaproteobacteria G Periplasmic binding protein domain - - - - - - - - - - - - Peripla_BP_4 k141_14421_1 265072.Mfla_0351 2.42e-49 167.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,2KKMM@206350|Nitrosomonadales 206350|Nitrosomonadales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_14421_2 393595.ABO_2014 1.57e-25 98.6 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XKMB@135619|Oceanospirillales 135619|Oceanospirillales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_14421_3 1137799.GZ78_02405 1.03e-99 306.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XH25@135619|Oceanospirillales 135619|Oceanospirillales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_12456_2 998674.ATTE01000001_gene378 2.99e-117 355.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,4602P@72273|Thiotrichales 72273|Thiotrichales G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_5460_1 443152.MDG893_02350 1.02e-68 214.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,466K8@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_4774_1 1288826.MSNKSG1_04811 1.55e-69 218.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,1RR1N@1236|Gammaproteobacteria,469WK@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, periplasmic component - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_4774_2 1288826.MSNKSG1_04816 1.97e-33 126.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_8270_1 95619.PM1_0218375 2.56e-94 281.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria 1224|Proteobacteria F Belongs to the SAICAR synthetase family purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 SAICAR_synt k141_8270_2 1454004.AW11_03945 4.08e-65 206.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,1KQW1@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_15152_1 1278309.KB907100_gene2302 6.44e-173 486.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XHMA@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_15152_2 1278309.KB907100_gene2303 2.79e-75 227.0 COG3312@1|root,COG3312@2|Bacteria,1QSYB@1224|Proteobacteria,1RWKF@1236|Gammaproteobacteria,1XMCQ@135619|Oceanospirillales 135619|Oceanospirillales C ATP synthase I chain - - - - - - - - - - - - ATP-synt_I k141_15152_3 1278309.KB907100_gene2304 2.74e-187 522.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales 135619|Oceanospirillales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_15152_5 1278309.KB907100_gene2306 4.86e-52 169.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XJMN@135619|Oceanospirillales 135619|Oceanospirillales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_15152_6 1278309.KB907100_gene2307 1.86e-106 309.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1XK2G@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_1282_1 1220582.RRU01S_07_01000 1.11e-25 102.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,4B9FB@82115|Rhizobiaceae 28211|Alphaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) hpaG - - - - - - - - - - - FAA_hydrolase k141_1282_2 1282356.H045_00355 1.43e-13 71.2 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1YMYW@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E GMC oxidoreductase alkJ - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_14435_2 1123399.AQVE01000002_gene2266 1.71e-10 62.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,461FR@72273|Thiotrichales 72273|Thiotrichales S RDD family - - - - - - - - - - - - RDD k141_13158_1 472759.Nhal_3889 6.04e-25 100.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1WXKR@135613|Chromatiales 135613|Chromatiales NU Pilus assembly protein PilO - - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_18046_1 323261.Noc_2672 4.65e-55 196.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales 135613|Chromatiales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_22183_1 1120965.AUBV01000010_gene2754 0.000317 49.3 COG2911@1|root,COG3210@1|root,COG5492@1|root,COG5563@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,COG5563@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia 976|Bacteroidetes G Protein conserved in bacteria - - - - - - - - - - - - DUF4394,Gal_Lectin k141_5473_1 2340.JV46_04650 4.18e-141 411.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos k141_5473_2 493475.GARC_2259 2.13e-205 591.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4650I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) dauA_1 - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_17276_1 1278309.KB907100_gene2124 0.0 1001.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4 k141_17276_2 1278309.KB907100_gene2125 3.09e-78 234.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XKPZ@135619|Oceanospirillales 135619|Oceanospirillales C cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 k141_17276_3 1278309.KB907100_gene2126 3.29e-274 763.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XHTD@135619|Oceanospirillales 135619|Oceanospirillales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_11059_1 1439940.BAY1663_02036 1.55e-44 154.0 COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1S9HC@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Molecular chaperone - - - - - - - - - - - - DNAJ_related,DnaJ k141_15932_1 1163408.UU9_14375 1.73e-120 376.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3U5@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07789 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2 - - ACR_tran k141_7535_1 90814.KL370891_gene1377 3.12e-97 297.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2,Usp k141_8287_1 472759.Nhal_0325 1.1e-55 183.0 COG3176@1|root,COG3176@2|Bacteria,1P4U9@1224|Proteobacteria,1T162@1236|Gammaproteobacteria,1X2N2@135613|Chromatiales 135613|Chromatiales S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5 k141_18047_1 3694.POPTR_0001s03220.1 3.24e-28 112.0 28Q0M@1|root,2QWP8@2759|Eukaryota,37SGC@33090|Viridiplantae 33090|Viridiplantae S Zinc knuckle family protein - - - - - - - - - - - - MP,RVP,zf-CCHC k141_18698_1 665029.EAMY_2239 1.95e-20 89.7 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,3X64P@551|Erwinia 1236|Gammaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_18698_2 1384065.JAGS01000001_gene2341 5.8e-10 61.6 COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WII0@541000|Ruminococcaceae 186801|Clostridia G Phosphoglycerate mutase family cobC - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_4781_1 743720.Psefu_0504 1.84e-22 101.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YY8B@136845|Pseudomonas putida group 1236|Gammaproteobacteria T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_2632_1 1237149.C900_04180 1.7e-113 338.0 COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,47Q0J@768503|Cytophagia 976|Bacteroidetes S Protease prsW family - - - - - - - - - - - - PrsW-protease k141_20018_1 1131553.JIBI01000017_gene577 7.19e-142 433.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales 28216|Betaproteobacteria L RNA polymerase recycling family C-terminal - - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N k141_16573_1 1046724.KB889876_gene340 1.19e-93 295.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria,467PM@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_17277_1 1278309.KB907100_gene2157 9.32e-68 210.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XK6E@135619|Oceanospirillales 135619|Oceanospirillales L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_11060_2 1231185.BAMP01000013_gene1946 1.54e-28 112.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,43HWQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE_1 - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_5474_1 384765.SIAM614_05518 1.66e-52 174.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator iclR - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_18048_2 367336.OM2255_12115 7.93e-47 160.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria 28211|Alphaproteobacteria M shape-determining protein MreC mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_3376_1 402881.Plav_2273 4.69e-27 102.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria,1JP07@119043|Rhodobiaceae 28211|Alphaproteobacteria H MoaE protein moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE k141_3376_2 644076.SCH4B_0344 4.25e-35 121.0 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2UF4F@28211|Alphaproteobacteria,4NCJ4@97050|Ruegeria 28211|Alphaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_9034_1 225937.HP15_1351 7.15e-102 305.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,4655S@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-2 family transporter protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_9677_1 1278309.KB907100_gene1819 1.17e-80 242.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1XJD0@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_9677_2 1278309.KB907100_gene1818 5.13e-166 466.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XIR0@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_9677_3 1278309.KB907100_gene1817 7.51e-140 401.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1XJNR@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_9677_4 1232683.ADIMK_1617 1.13e-68 222.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_2771_1 697282.Mettu_3799 2.96e-86 277.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XE9Y@135618|Methylococcales 135618|Methylococcales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_17403_1 323850.Shew_2833 5.93e-75 233.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,2QAX8@267890|Shewanellaceae 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_16706_1 631362.Thi970DRAFT_03838 2.28e-27 110.0 COG2232@1|root,COG2232@2|Bacteria 2|Bacteria V ATP-grasp domain - - - - - - - - - - - - ATP-grasp_3 k141_4051_1 1101195.Meth11DRAFT_2524 4.69e-122 355.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,2KM27@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF692) - - - ko:K09930 - - - - ko00000 - - - DUF2063,DUF692 k141_691_1 1437824.BN940_11806 8.78e-31 132.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,3T1RV@506|Alcaligenaceae 28216|Betaproteobacteria N Flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_18811_1 1288826.MSNKSG1_11033 3.67e-256 713.0 COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg,dCache_1 k141_19503_1 1280944.HY17_08835 8.87e-12 64.7 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,43W5K@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria MA20_36195 - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_19503_2 1122137.AQXF01000006_gene919 3.06e-62 196.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2U97G@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 k141_2059_2 1278078.G419_20960 1.38e-75 229.0 COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria,4G0W3@85025|Nocardiaceae 201174|Actinobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_20894_1 596154.Alide2_3749 2.02e-07 58.9 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_6868_1 1317124.DW2_15980 4.3e-43 146.0 COG2913@1|root,COG2913@2|Bacteria,1RHYM@1224|Proteobacteria,2UBU9@28211|Alphaproteobacteria,2XN76@285107|Thioclava 28211|Alphaproteobacteria J SmpA / OmlA family MA20_36760 - - - - - - - - - - - SmpA_OmlA k141_6868_2 1354722.JQLS01000008_gene1582 6.09e-30 114.0 COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,46QNV@74030|Roseovarius 28211|Alphaproteobacteria S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 k141_20106_1 1479237.JMLY01000001_gene1139 0.000235 44.7 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20106_2 395493.BegalDRAFT_1306 3.32e-49 161.0 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales 72273|Thiotrichales M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_20106_3 472759.Nhal_3569 7.58e-59 184.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales 135613|Chromatiales C Iron--sulfur cluster insertion protein erpA erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_20106_4 754476.Q7A_2823 4.24e-123 362.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales 72273|Thiotrichales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_11786_1 1288826.MSNKSG1_17151 0.0 1389.0 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,468GY@72275|Alteromonadaceae 1236|Gammaproteobacteria M esterase of the alpha-beta hydrolase superfamily plpD - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin k141_11786_2 1288826.MSNKSG1_17146 9.09e-97 286.0 COG3152@1|root,COG3152@2|Bacteria,1N85G@1224|Proteobacteria,1SCMI@1236|Gammaproteobacteria,468P3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_11786_3 1288826.MSNKSG1_17141 2.47e-79 236.0 2CJVY@1|root,2ZIH0@2|Bacteria,1P4ER@1224|Proteobacteria,1STI9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11786_4 1288826.MSNKSG1_17136 0.0 1759.0 COG0642@1|root,COG0834@1|root,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4667H@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07646,ko:K07679 ko02020,ko05133,map02020,map05133 M00454,M00477 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3 k141_11786_5 1288826.MSNKSG1_17131 4.5e-48 153.0 COG2040@1|root,COG2040@2|Bacteria,1N7A3@1224|Proteobacteria,1SCA1@1236|Gammaproteobacteria,468HX@72275|Alteromonadaceae 1236|Gammaproteobacteria E Protein of unknown function (DUF2789) XAC1354 - - - - - - - - - - - DUF2789 k141_11786_6 1288826.MSNKSG1_17126 6.35e-311 850.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,46632@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain pleD - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_11786_7 1288826.MSNKSG1_17121 2.85e-215 595.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,465QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_11786_8 1288826.MSNKSG1_17116 3.8e-170 476.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,467JP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigA - - ko:K09921 - - - - ko00000 - - - DUF484 k141_11786_9 1288826.MSNKSG1_17111 4.85e-215 594.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,464H0@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_11786_10 1288826.MSNKSG1_17106 2.43e-303 827.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4641G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_11786_12 1288826.MSNKSG1_17096 0.0 1890.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,464UY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Adenylate cyclase cyaA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365 Adenyl_cycl_N,Adenylate_cycl k141_11786_13 1288826.MSNKSG1_17091 0.0 1581.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1SJP8@1236|Gammaproteobacteria,46D4G@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS sensor diguanylate cyclase and - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9 k141_11786_14 1288826.MSNKSG1_17086 0.0 917.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_11786_15 1288826.MSNKSG1_17081 6.34e-255 701.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_11786_16 1288826.MSNKSG1_17076 1.43e-172 482.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,466SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3279 Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_11786_17 1288826.MSNKSG1_17071 8.95e-222 612.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,464JS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849 Porphobil_deam,Porphobil_deamC k141_11786_18 1288826.MSNKSG1_17066 2.85e-176 493.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,467BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1587 Uroporphyrinogen-III synthase hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0187,iSBO_1134.SBO_3815 HEM4 k141_11786_19 1288826.MSNKSG1_17061 1.55e-222 618.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317 HemX k141_11786_20 1288826.MSNKSG1_17056 7e-17 79.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,46647@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_2 k141_4079_1 1479237.JMLY01000001_gene2584 3.34e-22 101.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,46485@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_20895_1 1382230.ASAP_0978 8.7e-102 315.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2TT6V@28211|Alphaproteobacteria,2JPWF@204441|Rhodospirillales 204441|Rhodospirillales P Voltage gated chloride channel - - - - - - - - - - - - Voltage_CLC k141_6869_1 626887.J057_08791 4.01e-49 168.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RQ5E@1236|Gammaproteobacteria,466CU@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG1352 Methylase of chemotaxis methyl-accepting proteins pilK - 2.1.1.80 ko:K00575,ko:K02661 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035,ko02044 - - - CheR,CheR_N k141_6869_2 1121015.N789_09060 2.45e-30 120.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_20107_1 56780.SYN_00852 6.99e-64 213.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2MQ4F@213462|Syntrophobacterales 28221|Deltaproteobacteria M HlyD family secretion protein - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 k141_15262_1 1208321.D104_08430 2.21e-30 118.0 COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1 k141_15262_2 521719.ATXQ01000002_gene2541 3.92e-23 94.7 COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,1YFVS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase ycgF - - - - - - - - - - - EAL k141_15262_3 1168065.DOK_17510 1.74e-27 100.0 2E4GM@1|root,32ZBT@2|Bacteria,1N7CE@1224|Proteobacteria,1SCTA@1236|Gammaproteobacteria,1JBP2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4080_1 631362.Thi970DRAFT_00956 6.24e-136 387.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S - - - ko:K00184,ko:K21308 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 5.A.3 - - Fer4_11,Fer4_4,Fer4_7 k141_4080_2 1163617.SCD_n01211 8.21e-32 119.0 COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria 28216|Betaproteobacteria S DMSO reductase anchor subunit (DmsC) dmsC - - ko:K21309 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 - - - DmsC k141_6870_1 1278309.KB907110_gene3186 9.34e-12 64.7 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1XH9Y@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_6870_2 1278309.KB907110_gene3187 2.64e-131 381.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1XHJT@135619|Oceanospirillales 135619|Oceanospirillales C 1-deoxy-D-xylulose-5-phosphate synthase - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_20896_1 871968.DESME_04285 1.08e-12 70.1 COG1215@1|root,COG1215@2|Bacteria,1UE3Q@1239|Firmicutes,25BCZ@186801|Clostridia,264KP@186807|Peptococcaceae 186801|Clostridia M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_20896_2 572477.Alvin_2004 2.46e-55 179.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales 135613|Chromatiales E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 k141_20896_3 1122194.AUHU01000004_gene1617 4.88e-67 232.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,466AG@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9 k141_14621_2 857087.Metme_4126 4.69e-17 79.7 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XDMX@135618|Methylococcales 135618|Methylococcales H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_15263_1 511062.GU3_07805 3.52e-61 201.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1Y44T@135624|Aeromonadales 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Sigma54_activat k141_15263_2 1121918.ARWE01000001_gene1524 2.22e-49 174.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,43TUP@69541|Desulfuromonadales 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,SBP_bac_3,sCache_2 k141_14622_1 388399.SSE37_21870 7.3e-115 339.0 COG5285@1|root,COG5285@2|Bacteria,1NQ4U@1224|Proteobacteria,2TRH1@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - - - - - - - - - - PhyH k141_20108_1 1288826.MSNKSG1_00041 1.55e-84 249.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,466SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_20108_2 1288826.MSNKSG1_00036 6.11e-99 287.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,466GF@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_20108_3 1288826.MSNKSG1_00031 4.65e-47 157.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,46719@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0084 Mg-dependent DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_15264_2 1504981.KO116_0381 5.41e-66 210.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XIP5@135619|Oceanospirillales 135619|Oceanospirillales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_6871_1 69279.BG36_05560 2.19e-10 60.1 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRW0@28211|Alphaproteobacteria,43IFQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit - - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_6871_2 1278309.KB907099_gene2503 7.9e-222 618.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XIJI@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase M23 - - - ko:K19304 - - - - ko00000,ko01000,ko01002,ko01011 - - - OapA,Peptidase_M23 k141_20899_2 90813.JQMT01000001_gene1426 3.69e-54 186.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,45ZTE@72273|Thiotrichales 72273|Thiotrichales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_4081_1 472759.Nhal_0236 1.82e-67 215.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_4081_3 589865.DaAHT2_0430 2.14e-23 94.7 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria,2MNE9@213118|Desulfobacterales 28221|Deltaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_15265_1 292415.Tbd_0209 1.1e-50 171.0 COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,2WGG8@28216|Betaproteobacteria 28216|Betaproteobacteria L single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - - - - - - - - - - - k141_20109_1 1479237.JMLY01000001_gene3332 3.08e-70 213.0 COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S69D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphoesterase - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_20109_2 225937.HP15_2845 3.16e-122 351.0 28Z54@1|root,2ZKXF@2|Bacteria,1RAVB@1224|Proteobacteria,1S46P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - - k141_4082_1 796945.HMPREF1145_2109 1e-07 57.4 COG2199@1|root,COG3706@2|Bacteria,1UM30@1239|Firmicutes,25GDH@186801|Clostridia,2PTZX@265975|Oribacterium 186801|Clostridia T diguanylate cyclase - - - - - - - - - - - - GGDEF,Response_reg k141_20900_2 1442599.JAAN01000024_gene1853 1.09e-96 298.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_6872_1 324925.Ppha_2330 9.11e-43 155.0 COG2067@1|root,COG2067@2|Bacteria,1FDNA@1090|Chlorobi 1090|Chlorobi I PFAM membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_15266_1 1211579.PP4_52240 3.65e-15 76.3 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,1YVET@136845|Pseudomonas putida group 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_20110_1 1278309.KB907100_gene1897 3.08e-88 267.0 COG0790@1|root,COG0790@2|Bacteria,1R5EJ@1224|Proteobacteria,1SM9R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_20902_1 396588.Tgr7_1049 3.23e-86 270.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1WXYV@135613|Chromatiales 135613|Chromatiales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_20111_1 580332.Slit_2831 1.79e-36 126.0 COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria,2W3KZ@28216|Betaproteobacteria 28216|Betaproteobacteria P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_11790_1 1121937.AUHJ01000002_gene3434 6.46e-54 179.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,46AVD@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_18254_1 1249627.D779_3319 1.19e-226 639.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales 135613|Chromatiales J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_2209_1 626887.J057_11186 7.64e-49 171.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_12675_2 1288826.MSNKSG1_17451 0.0 1116.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,464VE@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_12675_3 1288826.MSNKSG1_17456 0.0 1116.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_12675_4 1288826.MSNKSG1_17461 1.79e-40 134.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,468FU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_12675_5 1288826.MSNKSG1_17466 7.12e-244 671.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,465FN@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_12675_6 1288826.MSNKSG1_17471 5.75e-133 377.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,466F3@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_12675_7 1288826.MSNKSG1_17476 3.55e-73 220.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,467QU@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808 FolB k141_12675_8 1288826.MSNKSG1_17481 2.14e-80 240.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,46782@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_1514_2 396588.Tgr7_0508 6.61e-62 195.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Peptidyl-prolyl cis-trans slyD GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_21704_1 207954.MED92_02206 1.6e-268 736.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,1RMG8@1236|Gammaproteobacteria,1XIGY@135619|Oceanospirillales 135619|Oceanospirillales I PFAM Acyl-CoA dehydrogenase, type 2 - - - - - - - - - - - - Acyl-CoA_dh_2,Acyl-CoA_dh_N k141_21704_2 1278309.KB907103_gene1151 9.52e-182 508.0 COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,1XHD7@135619|Oceanospirillales 135619|Oceanospirillales DT COG1718 Serine threonine protein kinase involved in cell cycle control - - 2.7.11.1 ko:K07178 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko01001,ko03009 - - - RIO1 k141_21704_3 1278309.KB907103_gene1152 0.0 1691.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1XHDB@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_3621_2 1535422.ND16A_1726 1.56e-86 263.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,2Q6JE@267889|Colwelliaceae 1236|Gammaproteobacteria S Ribosomal RNA large subunit methyltransferase D, RlmJ rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_21095_1 1278309.KB907106_gene1352 2.14e-114 335.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XI4E@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_10593_2 314275.MADE_1016315 5.6e-73 234.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,4640Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL k141_4312_1 1163409.UUA_09466 1.89e-94 289.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1X3HS@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO k141_9865_2 472759.Nhal_2479 7.32e-59 202.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WXWN@135613|Chromatiales 135613|Chromatiales I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_20379_1 1177154.Y5S_01713 8.78e-155 474.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,1XI5R@135619|Oceanospirillales 135619|Oceanospirillales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16 k141_94_1 1122132.AQYH01000005_gene732 1.37e-50 172.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,2TTA3@28211|Alphaproteobacteria 28211|Alphaproteobacteria K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_2916_1 870187.Thini_3427 3.66e-137 397.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,45ZNY@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_14076_1 1121403.AUCV01000007_gene1200 2.62e-150 451.0 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,42ZP1@68525|delta/epsilon subdivisions 1224|Proteobacteria M Glycosyl transferase family group 2 alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_21096_1 266809.PM03_14355 6e-137 409.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TUTB@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family dmgdh5 - 1.5.8.4 ko:K00315 ko00260,ko01100,map00260,map01100 - R01565 RC00181 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C k141_2210_1 1089552.KI911559_gene1029 5.13e-37 133.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,2JR26@204441|Rhodospirillales 204441|Rhodospirillales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF - 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_2210_2 1342302.JASC01000013_gene2776 1.45e-39 140.0 COG0384@1|root,COG0384@2|Bacteria,1MYCV@1224|Proteobacteria,2TUQJ@28211|Alphaproteobacteria,3ZVZ6@60136|Sulfitobacter 28211|Alphaproteobacteria S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF k141_1515_1 265072.Mfla_0626 1.96e-36 131.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KKQW@206350|Nitrosomonadales 206350|Nitrosomonadales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_1515_2 767434.Fraau_0482 1.02e-24 94.0 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1X821@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria VL23_05015 - - - - - - - - - - - zf-CHCC k141_1515_3 545264.KB898746_gene800 9.55e-33 125.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1WWQB@135613|Chromatiales 135613|Chromatiales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k141_13383_1 107635.AZUO01000001_gene963 3e-08 57.4 COG0280@1|root,COG0282@1|root,COG0280@2|Bacteria,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2TQQQ@28211|Alphaproteobacteria,36XT5@31993|Methylocystaceae 28211|Alphaproteobacteria C Acetokinase family ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_13383_2 314345.SPV1_14149 5.11e-32 121.0 COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria 1224|Proteobacteria P phosphate transport regulator (Distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_17538_1 225937.HP15_2391 3.29e-94 287.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - Polysacc_synt k141_17538_2 1177154.Y5S_03263 5.16e-77 236.0 COG0110@1|root,COG0110@2|Bacteria 2|Bacteria S O-acyltransferase activity - - - - - - - - - - - - Hexapep,Hexapep_2 k141_21705_1 1485545.JQLW01000010_gene1617 4.12e-34 139.0 COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase pleC - 2.7.13.3 ko:K07716 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE4,GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg k141_14783_1 765913.ThidrDRAFT_2951 2.32e-67 210.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales 135613|Chromatiales C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 k141_14783_2 472759.Nhal_0708 0.0 941.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales 135613|Chromatiales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_14783_3 1049564.TevJSym_bc00450 1.49e-11 62.0 COG2142@1|root,COG2142@2|Bacteria 2|Bacteria C succinate dehydrogenase activity sdhD GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - e_coli_core.b0722,iAF1260.b0722,iAPECO1_1312.APECO1_1356,iB21_1397.B21_00671,iBWG_1329.BWG_0581,iE2348C_1286.E2348C_0602,iEC042_1314.EC042_0740,iECABU_c1320.ECABU_c07680,iECBD_1354.ECBD_2938,iECB_1328.ECB_00682,iECDH10B_1368.ECDH10B_0789,iECDH1ME8569_1439.ECDH1ME8569_0681,iECD_1391.ECD_00682,iECED1_1282.ECED1_0692,iECIAI1_1343.ECIAI1_0696,iECIAI39_1322.ECIAI39_0680,iECNA114_1301.ECNA114_0658,iECO103_1326.ECO103_0716,iECO111_1330.ECO111_0739,iECO26_1355.ECO26_0783,iECOK1_1307.ECOK1_0722,iECP_1309.ECP_0734,iECS88_1305.ECS88_0748,iECSE_1348.ECSE_0782,iECSF_1327.ECSF_0655,iECUMN_1333.ECUMN_0800,iECW_1372.ECW_m0777,iEKO11_1354.EKO11_3157,iETEC_1333.ETEC_0733,iEcDH1_1363.EcDH1_2913,iEcE24377_1341.EcE24377A_0749,iEcHS_1320.EcHS_A0770,iEcSMS35_1347.EcSMS35_0735,iEcolC_1368.EcolC_2933,iJO1366.b0722,iJR904.b0722,iLF82_1304.LF82_2100,iNRG857_1313.NRG857_03215,iSBO_1134.SBO_0580,iSDY_1059.SDY_0660,iSFV_1184.SFV_0613,iSF_1195.SF0575,iSFxv_1172.SFxv_0634,iSSON_1240.SSON_0673,iS_1188.S0588,iUMN146_1321.UM146_14010,iUMNK88_1353.UMNK88_758,iUTI89_1310.UTI89_C0718,iWFL_1372.ECW_m0777,iY75_1357.Y75_RS03755,ic_1306.c0800 Sdh_cyt k141_11996_1 511062.GU3_12235 9.2e-120 357.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14,6.4.1.6 ko:K01474,ko:K10854 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_11996_2 1278309.KB907099_gene2944 4.17e-176 493.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1XIEB@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_7096_2 1123393.KB891316_gene1280 2e-06 53.9 COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2VRRF@28216|Betaproteobacteria,1KTHI@119069|Hydrogenophilales 119069|Hydrogenophilales M OmpA-like transmembrane domain - - - - - - - - - - - - OmpA_membrane k141_2211_1 292415.Tbd_1502 5.05e-32 124.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales 119069|Hydrogenophilales G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_3623_1 1232683.ADIMK_3829 3.31e-142 410.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,46A7B@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class I and II yfdZ GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K14261 - - - - ko00000,ko01000,ko01007 - - iEcSMS35_1347.EcSMS35_2531,iSBO_1134.SBO_2405 Aminotran_1_2 k141_9866_2 265072.Mfla_1474 2.79e-99 301.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,2KM5K@206350|Nitrosomonadales 206350|Nitrosomonadales O CAAX prenyl protease N-terminal, five membrane helices - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_21097_1 330214.NIDE3877 7.11e-48 157.0 COG3118@1|root,COG3118@2|Bacteria 2|Bacteria O belongs to the thioredoxin family trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_21097_2 207954.MED92_00680 7.38e-48 157.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XK48@135619|Oceanospirillales 135619|Oceanospirillales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_836_1 1318628.MARLIPOL_14290 4.07e-65 210.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_836_2 1049564.TevJSym_aj00400 3.42e-09 55.5 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1J60Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ k141_11328_1 1288826.MSNKSG1_02143 4.37e-119 346.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,466P4@72275|Alteromonadaceae 1236|Gammaproteobacteria C aldo keto reductase yhdN - 1.1.1.65 ko:K05275,ko:K18471 ko00640,ko00750,ko01100,ko01120,map00640,map00750,map01100,map01120 - R01708,R10718 RC00116,RC00739 ko00000,ko00001,ko01000 - - - Aldo_ket_red k141_14098_1 1121035.AUCH01000014_gene2354 1.74e-87 283.0 COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,2KXF8@206389|Rhodocyclales 206389|Rhodocyclales S Rhomboid family - - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid k141_11330_2 639283.Snov_4266 5.67e-27 109.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,3EZ58@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Amidohydrolase family - - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1,Urease_alpha k141_21727_2 2340.JV46_07620 1.39e-70 213.0 COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1T8KW@1236|Gammaproteobacteria,1JB0B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Ribulose bisphosphate carboxylase, small chain - - - - - - - - - - - - RuBisCO_small k141_14099_2 1179778.PMM47T1_22827 1.03e-08 61.2 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S von willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_14100_2 105559.Nwat_0698 2.25e-21 90.5 COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria,1X0WB@135613|Chromatiales 135613|Chromatiales J PFAM Cold-shock protein, DNA-binding - - - - - - - - - - - - CSD,Ribosomal_S30AE k141_1534_1 28229.ND2E_0402 8.93e-113 352.0 COG5635@1|root,COG5635@2|Bacteria,1MY1P@1224|Proteobacteria,1RZKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Nacht domain - - - - - - - - - - - - - k141_11333_1 1288826.MSNKSG1_12957 2.11e-257 707.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,46469@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_11333_2 1288826.MSNKSG1_12952 1.82e-70 217.0 COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,1S3YF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S methyltransferase - - - - - - - - - - - - PrmA k141_21728_1 1117647.M5M_11845 3.99e-50 169.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1J4JX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_21728_2 1123487.KB892863_gene1936 2.38e-43 160.0 COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,2VM72@28216|Betaproteobacteria,2KURH@206389|Rhodocyclales 206389|Rhodocyclales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_14101_1 1246995.AFR_04975 2.29e-14 81.3 COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4DGQR@85008|Micromonosporales 201174|Actinobacteria O Subtilase family mycP - 3.4.21.66 ko:K08651,ko:K14743 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_1535_1 443152.MDG893_07715 3.08e-184 518.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RZSX@1236|Gammaproteobacteria,46DGD@72275|Alteromonadaceae 1236|Gammaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_21729_1 1137799.GZ78_03315 3.02e-149 436.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XJ25@135619|Oceanospirillales 135619|Oceanospirillales S Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_1536_1 172088.AUGA01000013_gene7410 2.77e-92 285.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,3JVCG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Acyl-CoA reductase (LuxC) - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_11336_1 1123354.AUDR01000012_gene1637 3.32e-37 134.0 COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KSP1@119069|Hydrogenophilales 119069|Hydrogenophilales C Dihaem cytochrome c - - - - - - - - - - - - DHC k141_11336_2 1000565.METUNv1_00076 2.28e-13 68.2 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2VWE0@28216|Betaproteobacteria,2KX5T@206389|Rhodocyclales 206389|Rhodocyclales S Propeptide PepSY amd peptidase M4 - - - - - - - - - - - - PepSY k141_11336_3 1042375.AFPL01000036_gene3015 4.36e-14 69.7 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,4649A@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483,ko:K07660 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_1537_1 187272.Mlg_0956 6.98e-82 266.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales 135613|Chromatiales F PFAM glycosyl transferase family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_21115_2 686340.Metal_2029 2.86e-58 194.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XEJX@135618|Methylococcales 135618|Methylococcales H MoeA N-terminal region (domain I - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_17562_1 1036674.A28LD_2000 7.38e-17 81.3 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,2QG7P@267893|Idiomarinaceae 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_9879_2 644107.SL1157_3192 4.9e-68 212.0 COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2TU06@28211|Alphaproteobacteria,4NATR@97050|Ruegeria 28211|Alphaproteobacteria S chaperone TorD torD - - - - - - - - - - - Nitrate_red_del,YdaS_antitoxin k141_2934_1 1286093.C266_19900 0.000425 43.9 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,1K1GX@119060|Burkholderiaceae 28216|Betaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_2934_2 396588.Tgr7_1968 1.02e-113 338.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1WWRA@135613|Chromatiales 135613|Chromatiales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_7119_2 243233.MCA2795 9.39e-35 122.0 COG1942@1|root,COG1942@2|Bacteria,1N1GC@1224|Proteobacteria,1SB41@1236|Gammaproteobacteria,1XFD8@135618|Methylococcales 135618|Methylococcales S Macrophage migration inhibitory factor - - - - - - - - - - - - MIF k141_846_2 998674.ATTE01000001_gene4298 1.51e-76 233.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,460ID@72273|Thiotrichales 72273|Thiotrichales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_4995_2 1121479.AUBS01000007_gene2284 1.82e-29 112.0 COG0546@1|root,COG0546@2|Bacteria,1RB0Z@1224|Proteobacteria,2U5DF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S HAD-superfamily hydrolase subfamily IA, variant gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_4331_1 1121931.AUHG01000012_gene2736 4.05e-38 141.0 2E3RJ@1|root,32YP7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_18264_1 1054213.HMPREF9946_04811 1.94e-17 83.6 COG5653@1|root,COG5653@2|Bacteria,1RINE@1224|Proteobacteria,2U8NS@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_15517_1 1163409.UUA_15458 7.51e-19 81.6 COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,1RPCK@1236|Gammaproteobacteria,1X3GC@135614|Xanthomonadales 135614|Xanthomonadales F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK k141_15517_2 1234364.AMSF01000059_gene949 4.4e-91 285.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1X3YJ@135614|Xanthomonadales 135614|Xanthomonadales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_12693_1 235909.GK3120 1.64e-35 132.0 COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,4HG7P@91061|Bacilli,1WGU9@129337|Geobacillus 91061|Bacilli M Cytidylyltransferase neuA - 2.7.7.82 ko:K18431 ko00520,map00520 - R10182 RC00152 ko00000,ko00001,ko01000 - - - CTP_transf_3 k141_12693_3 189425.PGRAT_15850 0.000187 47.8 COG0535@1|root,COG0535@2|Bacteria,1UA7D@1239|Firmicutes,4IKIK@91061|Bacilli,26TI9@186822|Paenibacillaceae 91061|Bacilli C radical SAM protein - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_20396_1 1208323.B30_03275 3.07e-94 286.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TQVM@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapL - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_15639_4 1288826.MSNKSG1_09438 6.19e-115 331.0 COG1309@1|root,COG1309@2|Bacteria,1RGJ3@1224|Proteobacteria,1S2ZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator pfiT - - - - - - - - - - - TetR_C_4,TetR_N k141_15639_5 1288826.MSNKSG1_09443 3.35e-186 533.0 COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,1RR9Q@1236|Gammaproteobacteria,465U3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Pfam:DUF1446 atuA - - - - - - - - - - - AtuA k141_21926_1 1278309.KB907099_gene2569 1.78e-89 273.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,1XJT7@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_12162_2 706436.HMPREF9074_08675 1.72e-37 135.0 COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia,1EQ3A@1016|Capnocytophaga 976|Bacteroidetes F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_17012_1 1279019.ARQK01000047_gene1036 3.65e-228 652.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_5884_1 1265313.HRUBRA_00800 2.68e-81 257.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5FS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V MacB-like periplasmic core domain VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_19800_1 292415.Tbd_1569 8.42e-101 303.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,1KSVK@119069|Hydrogenophilales 119069|Hydrogenophilales E DegT/DnrJ/EryC1/StrS aminotransferase family - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_13524_1 105559.Nwat_1344 3.92e-66 230.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1WWAA@135613|Chromatiales 135613|Chromatiales O peptidylprolyl isomerase - - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 k141_3124_1 1134474.O59_004072 3.16e-76 244.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1T0B8@1236|Gammaproteobacteria 1236|Gammaproteobacteria T conserved protein, contains FHA domain - - - ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA k141_12863_1 999547.KI421500_gene1728 1.61e-50 164.0 COG1917@1|root,COG1917@2|Bacteria,1RH8X@1224|Proteobacteria,2U7MT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 k141_8027_1 1278309.KB907101_gene587 5.02e-305 838.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RNHN@1236|Gammaproteobacteria,1XI9J@135619|Oceanospirillales 135619|Oceanospirillales I AMP-binding enzyme C-terminal domain - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_10788_1 1316927.ATKI01000087_gene2028 1.57e-19 100.0 COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,1T1GM@1236|Gammaproteobacteria,1YMMJ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria H receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_10024_1 1288826.MSNKSG1_08328 1.84e-41 145.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,464JE@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_10024_2 1288826.MSNKSG1_08323 6.65e-199 551.0 COG3315@1|root,COG3315@2|Bacteria,1RCET@1224|Proteobacteria,1S2A1@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG3315 O-Methyltransferase involved in polyketide biosynthesis - - - - - - - - - - - - LCM k141_10024_3 1288826.MSNKSG1_08318 2.3e-293 801.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria,46596@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG2233 Xanthine uracil permeases uraA GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082 - ko:K02824,ko:K09016 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.1.3 - iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189,iSFxv_1172.SFxv_2795,iS_1188.S2690 Xan_ur_permease k141_10024_4 1288826.MSNKSG1_08313 3.43e-146 412.0 COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,465GY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iAF1260.b2498,iAPECO1_1312.APECO1_4071,iB21_1397.B21_02352,iBWG_1329.BWG_2262,iE2348C_1286.E2348C_2723,iEC042_1314.EC042_2699,iEC55989_1330.EC55989_2783,iECABU_c1320.ECABU_c27980,iECBD_1354.ECBD_1190,iECB_1328.ECB_02390,iECDH10B_1368.ECDH10B_2664,iECDH1ME8569_1439.ECDH1ME8569_2424,iECD_1391.ECD_02390,iECED1_1282.ECED1_2921,iECH74115_1262.ECH74115_3720,iECIAI1_1343.ECIAI1_2550,iECIAI39_1322.ECIAI39_2639,iECNA114_1301.ECNA114_2571,iECO103_1326.ECO103_3015,iECO111_1330.ECO111_3222,iECO26_1355.ECO26_3545,iECOK1_1307.ECOK1_2794,iECP_1309.ECP_2500,iECS88_1305.ECS88_2669,iECSE_1348.ECSE_2784,iECSF_1327.ECSF_2339,iECSP_1301.ECSP_3437,iECUMN_1333.ECUMN_2811,iECW_1372.ECW_m2721,iEKO11_1354.EKO11_1236,iETEC_1333.ETEC_2603,iEcDH1_1363.EcDH1_1171,iEcE24377_1341.EcE24377A_2781,iEcHS_1320.EcHS_A2633,iEcSMS35_1347.EcSMS35_2645,iEcolC_1368.EcolC_1178,iG2583_1286.G2583_3021,iJN746.PP_0746,iJO1366.b2498,iJR904.b2498,iLF82_1304.LF82_2383,iNRG857_1313.NRG857_12410,iSFV_1184.SFV_2543,iSF_1195.SF2542,iS_1188.S2691,iSbBS512_1146.SbBS512_E2872,iUMN146_1321.UM146_04235,iUMNK88_1353.UMNK88_3094,iWFL_1372.ECW_m2721,iY75_1357.Y75_RS13040,ic_1306.c3015 UPRTase k141_10024_5 1288826.MSNKSG1_08308 9.43e-40 145.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,465FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_21261_1 765911.Thivi_1977 2.27e-77 246.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1WWYR@135613|Chromatiales 135613|Chromatiales S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA k141_2378_1 768671.ThimaDRAFT_1285 1.13e-40 142.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales 135613|Chromatiales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_2378_2 1117647.M5M_11840 1.07e-23 100.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1J612@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yigA - - ko:K09921 - - - - ko00000 - - - DUF484 k141_17753_1 1026882.MAMP_02063 6.15e-59 190.0 COG1226@1|root,COG1226@2|Bacteria,1QYC1@1224|Proteobacteria 1224|Proteobacteria P COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 k141_18421_2 384765.SIAM614_11588 1.21e-14 73.6 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2U6G5@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - CbiA k141_1723_1 1122201.AUAZ01000005_gene663 6.17e-05 45.1 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,467QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_5885_1 243233.MCA2283 1.1e-52 183.0 COG0439@1|root,COG0439@2|Bacteria,1NHC0@1224|Proteobacteria 1224|Proteobacteria I Biotin carboxylase - - - - - - - - - - - - - k141_6533_1 1278309.KB907099_gene2762 1.1e-145 418.0 COG0665@1|root,COG0665@2|Bacteria,1MVG3@1224|Proteobacteria,1RT6W@1236|Gammaproteobacteria,1XHRN@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_6533_2 1278309.KB907099_gene2761 1.87e-208 580.0 COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1S0HY@1236|Gammaproteobacteria,1XINQ@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_6533_3 1278309.KB907099_gene2760 1.25e-68 219.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RPU7@1236|Gammaproteobacteria,1XH5G@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_13526_1 768671.ThimaDRAFT_0873 1.23e-38 142.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales 135613|Chromatiales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_13526_2 1232437.KL662015_gene1255 2.91e-10 61.6 COG2909@1|root,COG3187@1|root,COG2909@2|Bacteria,COG3187@2|Bacteria 2|Bacteria O response to heat - - - ko:K03668,ko:K03929 - - - - ko00000,ko01000 - CE10 - GerE,META k141_12864_1 983545.Glaag_4490 7.52e-112 348.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_303_1 1357272.AVEO02000134_gene900 1.61e-104 338.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C indolepyruvate ferredoxin oxidoreductase iorA - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_303_2 1278309.KB907099_gene2565 2.39e-54 184.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XKRC@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - ko:K14055 - - - - ko00000 - - - Usp k141_303_3 1278309.KB907099_gene2564 1.76e-75 248.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_20572_1 2340.JV46_21260 1.66e-240 666.0 COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1J4ZH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k141_12163_1 1049564.TevJSym_bi00190 9.65e-161 470.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_19802_1 754477.Q7C_2557 1.01e-46 173.0 COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,461KU@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,PAS_3,Response_reg,dCache_2 k141_1724_1 1278309.KB907099_gene3059 5.09e-102 301.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,1XHJQ@135619|Oceanospirillales 135619|Oceanospirillales E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_10025_1 1177154.Y5S_00833 1.72e-70 237.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XKXU@135619|Oceanospirillales 135619|Oceanospirillales M COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - - - - - - - - - - Sulfatase k141_17014_1 1278309.KB907109_gene3284 1.84e-08 54.3 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XHRU@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_17014_2 1278309.KB907109_gene3285 3.92e-68 207.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1XKGW@135619|Oceanospirillales 135619|Oceanospirillales C iron-sulfur cluster insertion protein erpA erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_17014_3 225937.HP15_4031 2.1e-14 71.2 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,1RY4A@1236|Gammaproteobacteria,46513@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily xylE - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_304_1 1278307.KB906982_gene3979 1.37e-46 170.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_21927_1 269799.Gmet_1141 4.78e-107 348.0 COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,437D2@68525|delta/epsilon subdivisions,2XA15@28221|Deltaproteobacteria,43VQR@69541|Desulfuromonadales 28221|Deltaproteobacteria S homolog of phage Mu protein gp47 - - - - - - - - - - - - - k141_21927_2 269799.Gmet_1142 1.65e-21 94.0 COG3292@1|root,COG3292@2|Bacteria,1QMJ4@1224|Proteobacteria,42RQF@68525|delta/epsilon subdivisions,2WNII@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Two component regulator propeller - - - - - - - - - - - - Tail_P2_I k141_13527_1 1122137.AQXF01000003_gene2142 5.52e-11 62.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2TS11@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the UPF0246 family - - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_2380_1 713587.THITH_06490 7.78e-13 64.3 2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,1S9XM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2380_2 1249627.D779_3292 6.53e-15 75.9 29QAQ@1|root,30B9W@2|Bacteria,1RGQ5@1224|Proteobacteria,1S5E4@1236|Gammaproteobacteria,1WY7X@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_6534_1 543728.Vapar_0215 2.73e-21 96.3 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHAU@28216|Betaproteobacteria,4AB4Y@80864|Comamonadaceae 28216|Betaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - PEGA,Pkinase k141_12866_1 1232683.ADIMK_1509 6.9e-91 289.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_15640_1 1278309.KB907102_gene202 2.62e-114 359.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XI40@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,NMT1,PAS,PAS_3,PAS_9 k141_15640_2 1278309.KB907102_gene201 3.69e-49 158.0 COG2863@1|root,COG2863@2|Bacteria 2|Bacteria C cytochrome - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C,Cytochrome_CBB3 k141_15640_3 1278309.KB907102_gene200 8.9e-36 132.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XI8E@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_19159_1 1288826.MSNKSG1_06793 3.21e-154 435.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46712@72275|Alteromonadaceae 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_19159_2 1288826.MSNKSG1_06788 9.67e-286 794.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,464IG@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 k141_1725_1 292415.Tbd_1286 4.68e-45 166.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process - - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - DUF4114,Metallophos k141_7277_1 1288826.MSNKSG1_11158 2.94e-62 192.0 COG1846@1|root,COG1846@2|Bacteria,1RJEE@1224|Proteobacteria,1SBSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K MarR family - - - - - - - - - - - - MarR_2 k141_7277_2 1288826.MSNKSG1_11153 8e-123 351.0 2E9MD@1|root,333U1@2|Bacteria,1N912@1224|Proteobacteria,1SBKC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) - - - - - - - - - - - - DUF1282,Yip1 k141_7277_3 1288826.MSNKSG1_11148 7.42e-150 422.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,467AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein, hemolysin III homolog yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_7277_4 1288826.MSNKSG1_11143 6.22e-138 390.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,465N9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the WrbA family wrbA GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_7277_5 1288826.MSNKSG1_11108 1.19e-167 468.0 COG0664@1|root,COG0664@2|Bacteria,1N0FR@1224|Proteobacteria,1SD0C@1236|Gammaproteobacteria,46BQP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding k141_7277_6 1288826.MSNKSG1_11103 8.63e-200 555.0 COG0679@1|root,COG0679@2|Bacteria,1RDRQ@1224|Proteobacteria,1RTUH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans,SBF k141_7277_7 1288826.MSNKSG1_11098 4.06e-137 390.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1S1S4@1236|Gammaproteobacteria,46AI9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1230 Co Zn Cd efflux system component - - - - - - - - - - - - Cation_efflux k141_7277_8 1288826.MSNKSG1_11093 4.19e-104 301.0 COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1S8VE@1236|Gammaproteobacteria,46828@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional cadR - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_7277_9 351348.Maqu_1295 1.62e-13 72.0 COG1422@1|root,COG1422@2|Bacteria,1N972@1224|Proteobacteria,1SFCG@1236|Gammaproteobacteria,4699J@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1090) - - - - - - - - - - - - - k141_7277_10 1288826.MSNKSG1_11083 0.0 981.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,4665Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_7277_11 1288826.MSNKSG1_11078 9.36e-104 300.0 COG0589@1|root,COG0589@2|Bacteria,1RBPZ@1224|Proteobacteria,1S2AC@1236|Gammaproteobacteria,46AXK@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_2381_1 1313421.JHBV01000042_gene3355 1.53e-44 150.0 COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_20574_2 1122194.AUHU01000002_gene2749 8.25e-18 82.8 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,4675M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8653_1 1288826.MSNKSG1_07648 3.87e-300 818.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RYNH@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - - - - - - - - - - Peripla_BP_6 k141_8653_2 1288826.MSNKSG1_07643 5.55e-106 313.0 2A6N7@1|root,30VG1@2|Bacteria,1RDJ7@1224|Proteobacteria,1S69Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5161_1 298386.PBPRB1993 1.18e-130 377.0 28J9Q@1|root,2Z94J@2|Bacteria,1N9VS@1224|Proteobacteria,1RS49@1236|Gammaproteobacteria,1XWKG@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_16297_1 1278309.KB907102_gene137 3.21e-117 338.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1XIEM@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_16297_2 1278309.KB907102_gene136 1.66e-117 338.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1XJCG@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfB - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_16297_3 1278309.KB907102_gene135 2.74e-295 835.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XHNH@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_3802_1 83406.HDN1F_10370 4.53e-13 78.2 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1J65T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M silverDB VP1757 - - - - - - - - - - - Porin_4 k141_12180_1 207954.MED92_15048 2.36e-81 244.0 COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,1S44W@1236|Gammaproteobacteria,1XK8V@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_12180_2 207954.MED92_15053 5.11e-228 631.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XMZH@135619|Oceanospirillales 135619|Oceanospirillales P Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_12180_3 1122599.AUGR01000005_gene1889 2.58e-134 387.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,1XJCJ@135619|Oceanospirillales 135619|Oceanospirillales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_12180_4 1316927.ATKI01000065_gene2021 2.01e-28 120.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YMNV@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria NT methyl-accepting chemotaxis protein VPA0491 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_17041_1 1288826.MSNKSG1_10548 7.98e-161 454.0 COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,1S0IZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM NAD(P)H-binding - - - - - - - - - - - - Epimerase k141_8679_1 1288826.MSNKSG1_14327 8.9e-143 427.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,465IY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_1883_1 1469245.JFBG01000003_gene391 1.25e-59 197.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_10956_1 713586.KB900536_gene2191 9.18e-125 374.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_10956_2 1191523.MROS_0495 1.92e-37 132.0 COG0053@1|root,COG0053@2|Bacteria 2|Bacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - 2.5.1.105 ko:K04088,ko:K06897 ko00790,map00790 M00742 R10339 RC00121 ko00000,ko00001,ko00002,ko01000 - - - Cation_efflux k141_6012_1 396588.Tgr7_2005 1.42e-60 197.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1WXVZ@135613|Chromatiales 135613|Chromatiales C Belongs to the AlaDH PNT family - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_13747_1 1288826.MSNKSG1_04461 5.39e-56 192.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_13747_2 1288826.MSNKSG1_04456 5.08e-261 716.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,464J1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_13747_3 1288826.MSNKSG1_04451 1.46e-260 714.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,464UF@72275|Alteromonadaceae 1236|Gammaproteobacteria E chorismate mutase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_13747_4 1288826.MSNKSG1_04446 1.2e-261 716.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,465ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935 Aminotran_5 k141_13747_5 1288826.MSNKSG1_04441 0.0 1605.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,4643E@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_13747_6 1288826.MSNKSG1_04436 1.72e-209 578.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,465BY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N k141_2553_1 1163409.UUA_14319 1.41e-76 249.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1X2XY@135614|Xanthomonadales 135614|Xanthomonadales C Malic enzyme - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malate_DH,Malic_M,PTA_PTB,malic k141_7468_1 1410620.SHLA_16c000640 2.42e-60 211.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TZDF@28211|Alphaproteobacteria,4BP1X@82115|Rhizobiaceae 28211|Alphaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg k141_15090_1 1185766.DL1_12365 1.62e-121 354.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2XN4T@285107|Thioclava 28211|Alphaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_12372_1 1408445.JHXP01000047_gene1742 3.75e-45 150.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1JDP5@118969|Legionellales 118969|Legionellales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_12372_2 870187.Thini_3309 2.11e-232 658.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,46061@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_18591_1 1288826.MSNKSG1_05041 1.9e-162 462.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,464JF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006633,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008776,GO:0008980,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019541,GO:0019542,GO:0019665,GO:0019666,GO:0019752,GO:0032787,GO:0042710,GO:0043167,GO:0043169,GO:0043436,GO:0044010,GO:0044011,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046394,GO:0046395,GO:0046459,GO:0046872,GO:0046914,GO:0051703,GO:0051704,GO:0051790,GO:0055114,GO:0071704,GO:0072330,GO:0090605,GO:0090609,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.7.2.1,2.7.2.15 ko:K00925,ko:K00932 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3309,iECS88_1305.ECS88_3508,iEcSMS35_1347.EcSMS35_3411,iLF82_1304.LF82_2233,iSDY_1059.SDY_2492,iUTI89_1310.UTI89_C3550,iYL1228.KPN_02687 Acetate_kinase k141_18591_2 1288826.MSNKSG1_05046 0.0 1331.0 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465EN@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CHASE5,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS_4,PAS_9,Response_reg k141_5386_1 1349767.GJA_4841 4.39e-37 139.0 COG0501@1|root,COG0501@2|Bacteria,1R47C@1224|Proteobacteria,2VS05@28216|Betaproteobacteria 28216|Betaproteobacteria O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_11633_1 983545.Glaag_3204 2.81e-78 257.0 28HYP@1|root,2Z842@2|Bacteria,1N96P@1224|Proteobacteria,1RQCQ@1236|Gammaproteobacteria,4659S@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17195_1 439235.Dalk_1928 1.62e-126 369.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_8202_1 1358423.N180_15790 1.88e-51 180.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1IPXI@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_8202_2 187272.Mlg_0956 0.0 1051.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales 135613|Chromatiales F PFAM glycosyl transferase family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_7469_1 1122939.ATUD01000001_gene473 8.64e-19 85.5 COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria 84995|Rubrobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_19965_1 697282.Mettu_0563 9.4e-102 339.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX1M@1236|Gammaproteobacteria,1XG7H@135618|Methylococcales 135618|Methylococcales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_10231_2 246199.CUS_7543 1.54e-24 100.0 COG0745@1|root,COG0745@2|Bacteria,1TRS2@1239|Firmicutes,24AF1@186801|Clostridia,3WIJ9@541000|Ruminococcaceae 186801|Clostridia T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_10231_4 1163409.UUA_16718 4.94e-29 122.0 COG1413@1|root,COG1413@2|Bacteria,1N7WF@1224|Proteobacteria,1SS5I@1236|Gammaproteobacteria,1XA7X@135614|Xanthomonadales 135614|Xanthomonadales C E-Z type HEAT repeats - - - - - - - - - - - - HEAT_2 k141_10231_5 1340434.AXVA01000001_gene1164 1.55e-47 169.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZCR1@1386|Bacillus 91061|Bacilli M Glycosyl transferase family group 2 icaA - - - - - - - - - - - Chitin_synth_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k141_5387_1 1247024.JRLH01000001_gene968 2.78e-86 270.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272,ko:K21344 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECH74115_1262.ECH74115_4363,iECSP_1301.ECSP_4025,iECs_1301.ECs3935,iPC815.YPO0654,iZ_1308.Z4405 CTP_transf_like,PfkB k141_13749_1 384765.SIAM614_02581 8.92e-71 229.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_3 k141_17196_1 1232683.ADIMK_4112 1.88e-103 308.0 COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,1RZ8H@1236|Gammaproteobacteria,46CXF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_21423_1 488538.SAR116_2105 4.03e-142 429.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2U1PA@28211|Alphaproteobacteria,4BPCU@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain psrA - 1.8.5.6 ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_13768_1 1454004.AW11_01915 6.81e-51 180.0 COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria 1224|Proteobacteria L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_Tnp_1 k141_21445_1 1223523.H340_16456 1.28e-75 244.0 COG0019@1|root,COG0019@2|Bacteria,2HHG9@201174|Actinobacteria 201174|Actinobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_21445_2 1198232.CYCME_0935 5.13e-24 103.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,462F7@72273|Thiotrichales 72273|Thiotrichales T HDOD domain - - - - - - - - - - - - HDOD k141_15861_1 1288826.MSNKSG1_12417 1.88e-177 501.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RY35@1236|Gammaproteobacteria,46A6F@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_15861_2 1288826.MSNKSG1_12412 3.48e-288 790.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_15861_3 225937.HP15_3266 6.53e-36 123.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SCXD@1236|Gammaproteobacteria,468RC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_15861_4 1288826.MSNKSG1_12402 0.0 909.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,469WI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_9480_1 648885.KB316283_gene4030 1.5e-76 244.0 COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2TRUJ@28211|Alphaproteobacteria,1JQWE@119045|Methylobacteriaceae 28211|Alphaproteobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_1230_1 926562.Oweho_0732 1.25e-106 334.0 COG1409@1|root,COG1409@2|Bacteria,4NHXB@976|Bacteroidetes,1I958@117743|Flavobacteriia 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_3313_1 1288826.MSNKSG1_12862 5e-275 754.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,465EB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_3313_2 1288826.MSNKSG1_12867 3.14e-196 545.0 COG0745@1|root,COG0745@2|Bacteria,1RBSS@1224|Proteobacteria,1S20D@1236|Gammaproteobacteria,4676W@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Response_reg k141_3313_3 1288826.MSNKSG1_12872 1.87e-288 788.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,464NU@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2951 Membrane-bound lytic murein transglycosylase B - - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - PG_binding_1,SLT_2 k141_3313_4 1288826.MSNKSG1_12877 3.78e-152 429.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,46734@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rsuA - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_3313_5 1288826.MSNKSG1_12882 2.16e-101 295.0 COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,1S5WS@1236|Gammaproteobacteria,467N0@72275|Alteromonadaceae 1236|Gammaproteobacteria EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D VL23_12675 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_3313_6 1288826.MSNKSG1_12887 0.0 1608.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1QXG3@1224|Proteobacteria,1T3B7@1236|Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF k141_3313_7 1288826.MSNKSG1_12892 0.0 1063.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4664R@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_3313_8 1288826.MSNKSG1_12897 0.0 1544.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,469CM@72275|Alteromonadaceae 1236|Gammaproteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - - - - - - - - - - XFP,XFP_N k141_3313_9 1288826.MSNKSG1_12902 1.12e-142 402.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,465P3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) - - - - - - - - - - - - DUF1282 k141_3313_10 1288826.MSNKSG1_12907 5.15e-134 380.0 COG0625@1|root,COG0625@2|Bacteria,1RDBD@1224|Proteobacteria,1SYU8@1236|Gammaproteobacteria,466TK@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_N_3 k141_3313_11 1288826.MSNKSG1_12912 7.52e-262 718.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,465EE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_3313_12 1288826.MSNKSG1_12917 3.67e-160 449.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1SB50@1236|Gammaproteobacteria,467EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_3313_14 1288826.MSNKSG1_12927 0.0 1561.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,4657E@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_10247_1 207954.MED92_12286 1.7e-94 281.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,1XJP6@135619|Oceanospirillales 135619|Oceanospirillales J Pseudouridine synthase rluA - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_10247_2 1278309.KB907101_gene608 2.64e-177 499.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1XH5M@135619|Oceanospirillales 135619|Oceanospirillales CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_10247_3 1278309.KB907101_gene607 2.8e-243 679.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RYZX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M (Lipo)protein - - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_10247_4 1278309.KB907101_gene606 1.77e-186 521.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XHES@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_10247_5 1278309.KB907101_gene605 3.67e-95 278.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XJJA@135619|Oceanospirillales 135619|Oceanospirillales O Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_10247_6 1278309.KB907101_gene604 8.01e-203 566.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XIE3@135619|Oceanospirillales 135619|Oceanospirillales S Permease perM - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_10247_7 1278309.KB907101_gene603 3.56e-41 136.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the sulfur carrier protein TusA family - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_10247_8 1278309.KB907101_gene602 1.43e-254 708.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XIIJ@135619|Oceanospirillales 135619|Oceanospirillales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_19 k141_10247_9 1278309.KB907101_gene600 1.02e-231 647.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1XH2B@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_10975_1 1288826.MSNKSG1_08813 1.17e-63 197.0 COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,465TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase k141_10975_2 1288826.MSNKSG1_08818 4.18e-23 91.7 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,468F4@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0250 Transcription antiterminator rfaH GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_15109_1 998674.ATTE01000001_gene1999 1.72e-147 431.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales 72273|Thiotrichales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_1900_1 1288826.MSNKSG1_01743 1.05e-265 733.0 COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,4648Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_1900_2 1288826.MSNKSG1_01748 9.61e-78 232.0 2ET8P@1|root,33KSR@2|Bacteria,1NN60@1224|Proteobacteria,1SI47@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1900_3 1288826.MSNKSG1_01753 1.7e-132 377.0 COG3839@1|root,COG3839@2|Bacteria,1QXG5@1224|Proteobacteria,1T3B9@1236|Gammaproteobacteria,46AQA@72275|Alteromonadaceae 1236|Gammaproteobacteria G ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_1900_4 1288826.MSNKSG1_01758 3.3e-169 475.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,467K7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_6035_1 323261.Noc_0246 3.38e-77 253.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_2571_1 550540.Fbal_0107 3.78e-93 292.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_7486_1 305900.GV64_02385 8.41e-14 67.8 COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,1XKKP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF962) - - - - - - - - - - - - DUF962 k141_7486_2 312284.A20C1_06796 4.16e-07 52.0 COG3795@1|root,COG3795@2|Bacteria 2|Bacteria F YCII-related domain - - - - - - - - - - - - DoxX_2,YCII k141_13769_1 132113.XP_003492781.1 2.3e-49 176.0 COG2377@1|root,2QUN9@2759|Eukaryota,39RYP@33154|Opisthokonta,3BMM5@33208|Metazoa,3DQQZ@33213|Bilateria,426XQ@6656|Arthropoda,3SMSE@50557|Insecta 33208|Metazoa O Anhydro-N-acetylmuramic acid kinase - - - - - - - - - - - - AnmK k141_5406_1 1049564.TevJSym_al00370 1.63e-69 221.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1J54Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_16521_1 1278309.KB907101_gene627 9.54e-47 165.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XI2V@135619|Oceanospirillales 135619|Oceanospirillales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_16521_2 1278309.KB907101_gene628 2.04e-135 389.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,1XJD5@135619|Oceanospirillales 135619|Oceanospirillales S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_16521_3 1278309.KB907101_gene629 2.7e-22 92.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1XJCH@135619|Oceanospirillales 135619|Oceanospirillales Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_11 k141_3314_1 1041146.ATZB01000046_gene12 3.65e-15 80.1 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4B9N5@82115|Rhizobiaceae 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,MASE4,PAS_3,dCache_1 k141_18604_1 314256.OG2516_04209 1.57e-81 248.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,2PC8S@252301|Oceanicola 28211|Alphaproteobacteria E Serine acetyltransferase, N-terminal cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_15110_1 1137281.D778_00386 9e-61 199.0 COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia 976|Bacteroidetes M Murein transglycosylase mltD_2 - - - - - - - - - - - SLT k141_2572_1 672.VV93_v1c03380 6.81e-54 188.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XUT0@135623|Vibrionales 135623|Vibrionales GM nucleoside-diphosphate sugar epimerases - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_521_1 1298865.H978DRAFT_2689 7.7e-101 317.0 COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,466BY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_521_2 1278309.KB907100_gene2209 9.49e-28 102.0 2EP7V@1|root,33GUI@2|Bacteria,1NPD0@1224|Proteobacteria,1SHPR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20706_1 1288826.MSNKSG1_14167 1.29e-70 227.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein ctpH - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_20706_2 1288826.MSNKSG1_14172 7.77e-160 466.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,464HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_8807_1 1278309.KB907099_gene2749 2.94e-85 255.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XIQH@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter ATP-binding protein - - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k141_8807_2 1278309.KB907099_gene2750 1.71e-169 480.0 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,1XJZX@135619|Oceanospirillales 135619|Oceanospirillales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD k141_7569_1 1288826.MSNKSG1_10308 1.28e-174 491.0 28Z9U@1|root,2ZM1P@2|Bacteria,1RBFF@1224|Proteobacteria,1S17A@1236|Gammaproteobacteria,4676U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7569_2 1288826.MSNKSG1_10303 1.06e-162 461.0 2F5Y3@1|root,33YGR@2|Bacteria,1QSJP@1224|Proteobacteria,1SR35@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7569_3 1288826.MSNKSG1_10298 1.92e-173 486.0 COG2267@1|root,COG2267@2|Bacteria,1QBU6@1224|Proteobacteria,1T7EN@1236|Gammaproteobacteria,46C57@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - - k141_7569_4 1288826.MSNKSG1_10293 0.0 1018.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,465CT@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport ethA - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 k141_7569_5 1288826.MSNKSG1_10288 9.51e-220 608.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1S2JB@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_7569_6 1122194.AUHU01000005_gene963 0.0 2505.0 COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1T315@1236|Gammaproteobacteria,46AA9@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - AAA_16,GAF,GGDEF,Pkinase k141_21549_1 1278309.KB907103_gene1102 1.76e-170 481.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XI3C@135619|Oceanospirillales 135619|Oceanospirillales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_21549_2 216142.LT40_06010 7.6e-20 87.4 COG2062@1|root,COG2062@2|Bacteria 2|Bacteria T phosphohistidine phosphatase, SixA sixA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_21549_3 1278309.KB907103_gene1104 2.74e-286 798.0 COG3307@1|root,COG3307@2|Bacteria,1N5VZ@1224|Proteobacteria,1RMC4@1236|Gammaproteobacteria,1XJGF@135619|Oceanospirillales 135619|Oceanospirillales M Virulence factor membrane-bound polymerase, C-terminal - - - ko:K13009 - - - - ko00000,ko01000,ko01005 - - - Wzy_C,Wzy_C_2 k141_21549_4 1278309.KB907103_gene1105 8.21e-143 410.0 COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,1T1JQ@1236|Gammaproteobacteria,1XRJF@135619|Oceanospirillales 135619|Oceanospirillales S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_21549_5 1278309.KB907103_gene1106 2.39e-137 395.0 COG2885@1|root,COG2885@2|Bacteria,1NF3D@1224|Proteobacteria,1SBSW@1236|Gammaproteobacteria,1XKGM@135619|Oceanospirillales 135619|Oceanospirillales M Domain of unknown function (DUF4892) - - - - - - - - - - - - DUF4892 k141_21549_6 1278309.KB907103_gene1107 3.38e-159 452.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1XHWW@135619|Oceanospirillales 135619|Oceanospirillales S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_17321_1 1188252.AJYK01000106_gene2031 2.25e-12 63.5 2E75R@1|root,331PX@2|Bacteria,1NAGT@1224|Proteobacteria,1SFBT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1993_1 1056820.KB900674_gene2616 1.67e-186 521.0 COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,1RR82@1236|Gammaproteobacteria,2PQ3I@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family nifH - 1.18.6.1 ko:K02588 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - Fer4_NifH k141_3436_1 396588.Tgr7_1557 8.18e-171 485.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_18115_1 1288826.MSNKSG1_04856 1.4e-187 523.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_18115_2 1318628.MARLIPOL_06259 2.24e-154 446.0 2EN2J@1|root,33FQS@2|Bacteria,1PFDP@1224|Proteobacteria,1SI7T@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18115_3 1288826.MSNKSG1_04846 7.8e-58 190.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,465PC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD_5 k141_12532_1 1278309.KB907106_gene1352 1.55e-102 304.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XI4E@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_12532_3 1279017.AQYJ01000019_gene1491 2.28e-47 152.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,467SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_20789_2 998674.ATTE01000001_gene632 1.88e-45 163.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,460A3@72273|Thiotrichales 72273|Thiotrichales L TIGRFAM ATP-dependent DNA helicase, RecQ - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_6160_1 102129.Lepto7375DRAFT_0713 5.65e-29 121.0 COG0358@1|root,COG0827@1|root,COG1203@1|root,COG0358@2|Bacteria,COG0827@2|Bacteria,COG1203@2|Bacteria,1GQMZ@1117|Cyanobacteria,1HHWG@1150|Oscillatoriales 1117|Cyanobacteria L CRISPR-associated helicase, Cas3 - - - - - - - - - - - - AAA_34,DUF3991,Helicase_C_4,Toprim_2 k141_4823_1 1265313.HRUBRA_02342 2.2e-11 63.2 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1J4Q7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_1135 ATP-grasp,Epimerase k141_4823_2 1395571.TMS3_0101380 1.2e-62 203.0 COG0730@1|root,COG0730@2|Bacteria,1RGCZ@1224|Proteobacteria,1S7QU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_4823_3 1278309.KB907104_gene847 1.19e-153 434.0 COG2055@1|root,COG2055@2|Bacteria,1Q4DG@1224|Proteobacteria,1RXZQ@1236|Gammaproteobacteria,1XQY5@135619|Oceanospirillales 135619|Oceanospirillales C Protein of unknown function (DUF3726) - - - - - - - - - - - - DUF3726 k141_4823_4 1278309.KB907104_gene848 0.0 1037.0 COG4367@1|root,COG4367@2|Bacteria,1MU6T@1224|Proteobacteria,1RNPG@1236|Gammaproteobacteria,1XIVN@135619|Oceanospirillales 135619|Oceanospirillales K negative regulation of transcription, DNA-templated - - - - - - - - - - - - - k141_5508_1 1288826.MSNKSG1_01338 0.0 1271.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_5508_2 1288826.MSNKSG1_01343 2.97e-212 586.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,464QD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2444 PALP k141_5508_3 1288826.MSNKSG1_01348 0.0 893.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,464C5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_5508_4 1288826.MSNKSG1_01353 0.0 1465.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4654N@72275|Alteromonadaceae 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS k141_5508_5 1288826.MSNKSG1_01358 1.24e-200 556.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,465UD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyrophosphatase mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 MazG k141_5508_6 225937.HP15_793 1.93e-75 225.0 2CECF@1|root,32RZM@2|Bacteria,1N130@1224|Proteobacteria,1S98I@1236|Gammaproteobacteria,468FH@72275|Alteromonadaceae 1236|Gammaproteobacteria S pilin assembly protein - - - - - - - - - - - - - k141_5508_7 1121935.AQXX01000087_gene4620 5.64e-14 68.6 2CECF@1|root,32RZM@2|Bacteria,1N130@1224|Proteobacteria,1S98I@1236|Gammaproteobacteria,1XM8I@135619|Oceanospirillales 135619|Oceanospirillales S pilin assembly protein - - - - - - - - - - - - - k141_5508_8 1288826.MSNKSG1_01373 0.0 1692.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,4646H@72275|Alteromonadaceae 1236|Gammaproteobacteria C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_4025 PEPcase k141_16630_1 1278309.KB907101_gene490 4.17e-120 349.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,1RMM9@1236|Gammaproteobacteria,1XH54@135619|Oceanospirillales 135619|Oceanospirillales S May be involved in the transport of PQQ or its precursor to the periplasm pqqB - - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 k141_16630_2 1278309.KB907101_gene491 4.86e-182 506.0 COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,1RP1V@1236|Gammaproteobacteria,1XH2V@135619|Oceanospirillales 135619|Oceanospirillales H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 k141_16630_3 1278309.KB907101_gene492 3.5e-52 165.0 2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria,1SCEZ@1236|Gammaproteobacteria,1XKZY@135619|Oceanospirillales 135619|Oceanospirillales S Coenzyme PQQ synthesis protein D (PqqD) pqqD - - ko:K06138 - - - - ko00000 - - - PqqD k141_17323_2 1198232.CYCME_0544 4.47e-24 97.8 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,4616Y@72273|Thiotrichales 72273|Thiotrichales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_18750_1 1382230.ASAP_2271 1.13e-10 63.2 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18750_2 1469245.JFBG01000027_gene1460 1.51e-48 167.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales 135613|Chromatiales GM NAD-dependent epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 k141_8349_1 1209072.ALBT01000052_gene554 3.52e-17 87.4 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1FGEP@10|Cellvibrio 1236|Gammaproteobacteria S Domain of unknown function (DUF4131) ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_8349_2 243277.VC_1880 5.02e-65 204.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XSNS@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_8349_3 1234364.AMSF01000016_gene1680 2.8e-09 57.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1X2X9@135614|Xanthomonadales 135614|Xanthomonadales V Part of the ABC transporter complex LolCDE involved in the translocation of lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_13217_1 519989.ECTPHS_03197 1.63e-181 528.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales 135613|Chromatiales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_13894_2 948565.AFFP02000010_gene1636 1.49e-47 158.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1Y8GN@135625|Pasteurellales 135625|Pasteurellales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_13894_3 519989.ECTPHS_03051 8.51e-87 265.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales 135613|Chromatiales P PFAM CBS domain - - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_3439_1 326297.Sama_3588 3.59e-52 176.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2Q9BN@267890|Shewanellaceae 1236|Gammaproteobacteria V PFAM ABC transporter related ybhF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_21551_1 765911.Thivi_4245 1.75e-100 315.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WW7D@135613|Chromatiales 135613|Chromatiales C Molybdopterin oxidoreductase Fe4S4 domain napA - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_10387_2 1121374.KB891585_gene2402 1.07e-121 355.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2797) LA2027 - - - - - - - - - - - DUF2797 k141_9613_1 1049564.TevJSym_ar00090 3.21e-221 616.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1J5D5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_9613_2 1122951.ATUE01000006_gene1370 3.17e-86 262.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,3NKMT@468|Moraxellaceae 1236|Gammaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_15981_1 1278309.KB907108_gene1608 7.41e-277 768.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XRYT@135619|Oceanospirillales 135619|Oceanospirillales K Activator of aromatic catabolism - - - - - - - - - - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_15981_2 1278309.KB907102_gene90 1.09e-21 90.1 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,1XJ5U@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_15177_1 1123279.ATUS01000002_gene171 1.06e-19 88.2 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1J4SN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_15177_2 1286106.MPL1_05679 1.14e-63 218.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales 72273|Thiotrichales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_18117_1 1317124.DW2_02769 3.5e-163 461.0 COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,2TRQ0@28211|Alphaproteobacteria,2XMII@285107|Thioclava 28211|Alphaproteobacteria U Sugar ABC transporter permease - - - ko:K17317 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_7570_1 743299.Acife_1820 1.24e-134 387.0 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,2NCVE@225057|Acidithiobacillales 225057|Acidithiobacillales C NADH ubiquinone oxidoreductase, 20 Kd subunit - - - - - - - - - - - - Oxidored_q6 k141_7570_2 243159.AFE_0939 6.8e-139 399.0 COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,2NC5H@225057|Acidithiobacillales 225057|Acidithiobacillales C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - - - - - - - - - - DHODB_Fe-S_bind,NAD_binding_1 k141_7570_3 298655.KI912266_gene2852 1.56e-06 48.9 COG0247@1|root,COG0247@2|Bacteria,2I3IR@201174|Actinobacteria,4EUJ2@85013|Frankiales 201174|Actinobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 k141_614_1 1278309.KB907105_gene1517 2.6e-229 648.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XH59@135619|Oceanospirillales 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_614_2 1122201.AUAZ01000011_gene1561 1.12e-113 339.0 COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria 1224|Proteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_614_3 1278309.KB907105_gene1518 1.28e-238 659.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XHVG@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_614_4 1278309.KB907105_gene1519 2.15e-23 98.2 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XHXQ@135619|Oceanospirillales 135619|Oceanospirillales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_17324_1 1288826.MSNKSG1_09148 8.39e-47 157.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4658M@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorC corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_17324_2 1288826.MSNKSG1_09153 2.19e-146 424.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_19451_1 234267.Acid_0309 1.1e-05 48.5 COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria 57723|Acidobacteria K Prokaryotic dksA/traR C4-type zinc finger - - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_8921_1 1122134.KB893651_gene1814 9.85e-36 133.0 COG0330@1|root,COG0330@2|Bacteria,1R93I@1224|Proteobacteria,1RPTI@1236|Gammaproteobacteria,1XINU@135619|Oceanospirillales 135619|Oceanospirillales O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 k141_8921_2 1278309.KB907110_gene3207 0.0 958.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XI1F@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_6162_1 1249627.D779_3662 1.81e-22 96.3 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales 135613|Chromatiales KT Fis Family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat k141_6162_2 395493.BegalDRAFT_3074 1.28e-80 253.0 COG0535@1|root,COG0535@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cofactor biosynthesis protein NifB nifB - - ko:K02585 - - - - ko00000 - - - Fer4_14,Nitro_FeMo-Co,Radical_SAM k141_3440_1 1121403.AUCV01000007_gene1200 8.09e-19 86.7 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,42ZP1@68525|delta/epsilon subdivisions 1224|Proteobacteria M Glycosyl transferase family group 2 alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_2002_3 1278309.KB907110_gene3177 1.09e-308 843.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1XI4J@135619|Oceanospirillales 135619|Oceanospirillales I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_2002_4 1122201.AUAZ01000003_gene2037 2.33e-57 182.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,466TN@72275|Alteromonadaceae 1236|Gammaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - iYL1228.KPN_03664 Biotin_lipoyl k141_2002_5 1278309.KB907110_gene3175 1.79e-89 263.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XJM2@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_2002_6 1278309.KB907110_gene3174 7.21e-219 607.0 COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1XH81@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF2333 k141_2002_7 1278309.KB907110_gene3173 3.86e-165 464.0 COG1192@1|root,COG1192@2|Bacteria,1MVEZ@1224|Proteobacteria,1RPWA@1236|Gammaproteobacteria,1XI4F@135619|Oceanospirillales 135619|Oceanospirillales D COG1192 ATPases involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_8952_1 247634.GPB2148_2077 2.2e-42 142.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1J6EU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised protein family UPF0047 yjbQ - - - - - - - - - - - UPF0047 k141_2701_1 1278309.KB907103_gene1042 9.96e-102 318.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XHR6@135619|Oceanospirillales 135619|Oceanospirillales C Succinyl-CoA ligase like flavodoxin domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_636_1 1158165.KB898872_gene763 1.14e-47 166.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1WWGZ@135613|Chromatiales 135613|Chromatiales J PFAM tRNA synthetase class II (G H P and S) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_15197_1 713586.KB900536_gene1783 4.71e-47 175.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k141_3458_1 69279.BG36_20280 6e-71 215.0 COG3293@1|root,COG3293@2|Bacteria,1RIVX@1224|Proteobacteria,2UA10@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 k141_11737_2 768671.ThimaDRAFT_3668 2.71e-177 501.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1WVY0@135613|Chromatiales 135613|Chromatiales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_6184_1 876044.IMCC3088_662 7.26e-74 236.0 COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria,1J7KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_8953_1 1288298.rosmuc_00722 2.76e-115 343.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,46Q7Y@74030|Roseovarius 28211|Alphaproteobacteria H Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_5535_1 1122134.KB893650_gene379 4.05e-24 101.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XJB4@135619|Oceanospirillales 135619|Oceanospirillales LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_5535_2 105559.Nwat_3068 1.16e-24 97.4 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales 135613|Chromatiales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_22248_1 517417.Cpar_0025 8.95e-11 59.7 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - PI-PLC-C1,Rhodanese k141_22248_2 400668.Mmwyl1_0423 1.72e-22 90.9 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,1SD0D@1236|Gammaproteobacteria 1236|Gammaproteobacteria H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_11310_2 1288826.MSNKSG1_17426 3.83e-97 283.0 2E8BZ@1|root,332QM@2|Bacteria,1NGCQ@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2489) - - - - - - - - - - - - DUF2489 k141_11310_3 1288826.MSNKSG1_17421 2.02e-95 288.0 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,465QR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - HDOD,tRNA_edit k141_10583_1 404589.Anae109_1614 1.27e-06 54.7 COG0517@1|root,COG1993@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,43BS4@68525|delta/epsilon subdivisions,2X72X@28221|Deltaproteobacteria 28221|Deltaproteobacteria K PFAM CBS domain containing protein - - - - - - - - - - - - CBS,DUF190 k141_2204_1 1234364.AMSF01000025_gene3684 6.46e-69 214.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1X303@135614|Xanthomonadales 135614|Xanthomonadales L exodeoxyribonuclease III xthA2 - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_2204_2 1215092.PA6_006_02400 4.34e-22 91.3 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1YCRD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Electron transfer flavoprotein domain etfB - - ko:K03521 - - - - ko00000 - - - ETF k141_4975_1 1288826.MSNKSG1_04326 8.72e-162 462.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,465B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DEAD box helicase family dbpA GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_4975_2 1288826.MSNKSG1_04321 1.74e-111 322.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,467D6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaiL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09912 - - - - ko00000 - - iECW_1372.ECW_m0432,iWFL_1372.ECW_m0432 DUF2058 k141_4975_3 225937.HP15_1326 1.68e-88 281.0 2DM3X@1|root,31MK7@2|Bacteria,1RFI0@1224|Proteobacteria,1S7WP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4297_1 1209072.ALBT01000032_gene2152 2.68e-173 503.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1FGUD@10|Cellvibrio 1236|Gammaproteobacteria L DHH family recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_15489_1 207954.MED92_14168 7.51e-274 757.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XHT5@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of fumarate from aspartate - - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_15489_2 207954.MED92_14163 1.49e-244 679.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XHZY@135619|Oceanospirillales 135619|Oceanospirillales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_9158_2 1288826.MSNKSG1_02916 0.0 1088.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,46481@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the glutamate synthase family HA62_33250 - - - - - - - - - - - Glu_synthase k141_18257_1 582744.Msip34_0615 3.11e-16 74.3 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KMQH@206350|Nitrosomonadales 206350|Nitrosomonadales F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ - - - - - - - - - - - NUDIX k141_18257_2 754476.Q7A_2070 7.22e-78 240.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,460HG@72273|Thiotrichales 72273|Thiotrichales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_18257_3 2340.JV46_14480 7.18e-72 228.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1J4Z7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Isocitrate icd GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Iso_dh k141_20383_1 1278309.KB907101_gene536 8.44e-303 826.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1XI41@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_4984_1 1131553.JIBI01000044_gene1397 2.39e-114 349.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,372DE@32003|Nitrosomonadales 28216|Betaproteobacteria G aldehyde-lyase activity xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_15506_1 1201293.AKXQ01000006_gene348 2.65e-17 83.6 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria 1236|Gammaproteobacteria N flagellar flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_15506_2 105559.Nwat_0929 1.72e-19 85.9 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1WWDH@135613|Chromatiales 135613|Chromatiales D Belongs to the ParA family - - - ko:K04562 - - - - ko00000,ko02035 - - - CbiA,ParA k141_100_1 1005048.CFU_4378 1.97e-128 381.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,472HD@75682|Oxalobacteraceae 28216|Betaproteobacteria C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_5737_1 1110502.TMO_2494 1.69e-18 89.7 COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JQPJ@204441|Rhodospirillales 204441|Rhodospirillales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_11320_3 316275.VSAL_I1037 6.12e-16 76.6 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_21105_2 391595.RLO149_c012800 1.9e-94 280.0 COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,2TUIK@28211|Alphaproteobacteria,2P21I@2433|Roseobacter 28211|Alphaproteobacteria J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k141_1519_1 344747.PM8797T_13947 0.000127 53.5 COG1520@1|root,COG1572@1|root,COG2373@1|root,COG2931@1|root,COG3203@1|root,COG3266@1|root,COG3391@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3203@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,2IZBV@203682|Planctomycetes 203682|Planctomycetes Q aggregation factor core protein MAFp3, isoform C - - - - - - - - - - - - Calx-beta,FG-GAP_2 k141_19646_1 717774.Marme_2954 1.29e-08 55.8 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XI0C@135619|Oceanospirillales 135619|Oceanospirillales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC k141_19646_2 1158762.KB898037_gene2262 9.14e-55 184.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales 135613|Chromatiales H Uroporphyrinogen III synthase - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_17547_2 2340.JV46_02620 9.99e-70 219.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,1JA3Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Prolyl 4-hydroxylase alpha subunit homologues. ybiX - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 k141_18971_2 1191523.MROS_2322 5.9e-62 201.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_Tnp_1,rve,rve_3 k141_18971_3 1122237.AUGQ01000023_gene2479 0.000867 41.2 COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria 201174|Actinobacteria L PFAM transposase IS3 IS911 family protein - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_18971_4 1249480.B649_07045 9.32e-17 90.1 COG5290@1|root,COG5290@2|Bacteria,1N3KW@1224|Proteobacteria,42PRG@68525|delta/epsilon subdivisions,2YRCV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - k141_11321_1 1209072.ALBT01000038_gene2365 1.2e-19 93.2 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1FFU3@10|Cellvibrio 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_21106_1 706587.Desti_1823 6.83e-37 142.0 COG0745@1|root,COG3290@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_2216_1 1123368.AUIS01000035_gene73 6.49e-25 103.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,Cache_3-Cache_2,HAMP,MCPsignal k141_2216_2 398767.Glov_0563 4.57e-60 195.0 COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria 1224|Proteobacteria Q Methyl-transferase - - - - - - - - - - - - Methyltransf_11 k141_5738_1 1182590.BN5_00522 2.04e-37 135.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1YF30@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_4319_1 1288826.MSNKSG1_13462 1.41e-253 701.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,464KD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_18258_1 1049564.TevJSym_aj00060 1.63e-49 181.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1J98N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_6393_1 1049564.TevJSym_ap00650 6.39e-91 273.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1J5PU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_6393_2 1335757.SPICUR_03195 2.53e-13 70.9 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales 135613|Chromatiales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_13390_1 1123228.AUIH01000002_gene1550 2.51e-50 182.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XI39@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein - - - ko:K07121 - - - - ko00000 - - - LppC k141_9870_1 1278309.KB907100_gene1994 3.05e-41 150.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XHZK@135619|Oceanospirillales 135619|Oceanospirillales U Type II and III secretion system protein pilQ - - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_9870_2 1278309.KB907100_gene1995 4.65e-102 298.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1XKCY@135619|Oceanospirillales 135619|Oceanospirillales NU Type 4 fimbrial biogenesis protein PilP pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_9870_3 1278309.KB907100_gene1996 5.36e-119 342.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1XJVN@135619|Oceanospirillales 135619|Oceanospirillales NU Pilus assembly protein PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_9870_4 1278309.KB907100_gene1997 2.12e-37 130.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1XJXN@135619|Oceanospirillales 135619|Oceanospirillales NU pilus assembly protein PilN - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_15507_2 1123368.AUIS01000001_gene1859 4.85e-07 50.8 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,2ND51@225057|Acidithiobacillales 225057|Acidithiobacillales S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_14081_1 1123360.thalar_00639 1.99e-57 187.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_12681_1 95619.PM1_0201095 3.22e-62 213.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_20384_2 1288826.MSNKSG1_06048 2.27e-148 421.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,4653C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_7104_1 754477.Q7C_342 1.11e-55 187.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,45ZUN@72273|Thiotrichales 72273|Thiotrichales E Amino acid kinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_7104_2 1249627.D779_0542 1.05e-121 372.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales 135613|Chromatiales P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_7822_1 582744.Msip34_0973 1.19e-124 384.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,2KKPG@206350|Nitrosomonadales 206350|Nitrosomonadales E Domain of unknown function (DUF3488) - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_7822_2 395493.BegalDRAFT_1363 5.91e-78 248.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,460RY@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_7822_3 395494.Galf_1823 1.04e-88 270.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales 28216|Betaproteobacteria S PFAM ATPase associated with various cellular activities AAA_3 moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_101_1 1328313.DS2_17287 5.28e-05 45.1 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,4677Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_101_2 1288826.MSNKSG1_00581 4.08e-37 125.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,467T8@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 k141_6394_2 1121479.AUBS01000004_gene2493 1.08e-31 115.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2U70I@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_17549_1 1278309.KB907102_gene30 2.01e-87 279.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XI0P@135619|Oceanospirillales 135619|Oceanospirillales D protein involved in exopolysaccharide biosynthesis - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz k141_17549_2 1278309.KB907102_gene29 2.75e-20 86.3 COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,1S34B@1236|Gammaproteobacteria,1XK8J@135619|Oceanospirillales 135619|Oceanospirillales GM capsular polysaccharide biosynthesis protein - - - - - - - - - - - - - k141_8499_1 1288826.MSNKSG1_06468 2.17e-173 508.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4647U@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_8499_2 1288826.MSNKSG1_06473 1.39e-230 638.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,464GC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - 4.4.1.11 ko:K01761,ko:K10764 ko00270,ko00450,ko00920,ko01100,map00270,map00450,map00920,map01100 - R00654,R01288,R04770 RC00020,RC00196,RC00348,RC01209,RC01210,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_2217_1 425104.Ssed_2962 1.17e-72 235.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,2QB35@267890|Shewanellaceae 1236|Gammaproteobacteria J PFAM beta-lactamase domain protein - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_18259_1 585.DR95_531 3.02e-16 79.0 2AXQF@1|root,31PR8@2|Bacteria,1RKX8@1224|Proteobacteria,1S6JS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18259_2 279280.Q6J1R9_9CAUD 5.31e-14 71.2 4QH0X@10239|Viruses,4QXIJ@35237|dsDNA viruses no RNA stage,4QSY6@28883|Caudovirales,4QNTU@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k141_15508_1 1123360.thalar_00684 8.6e-74 235.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_2218_2 207954.MED92_01569 1.37e-49 167.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XIUA@135619|Oceanospirillales 135619|Oceanospirillales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_10605_1 2340.JV46_28240 5.85e-97 307.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_17552_1 1134474.O59_004034 5.35e-42 145.0 COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,1RPY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Di-iron-containing protein involved in the repair of iron-sulfur clusters ytfE GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564 - ko:K07322 - - - - ko00000 - - iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820 Hemerythrin,ScdA_N k141_17552_2 498211.CJA_1546 1.21e-57 197.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1FI2C@10|Cellvibrio 1236|Gammaproteobacteria P Cytochrome C and Quinol oxidase polypeptide I norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_838_1 1278309.KB907100_gene2197 1.31e-258 716.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1S0HT@1236|Gammaproteobacteria,1XI5D@135619|Oceanospirillales 135619|Oceanospirillales T Bacterial regulatory protein, Fis family - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21280_2 1112217.PPL19_09241 1.96e-43 151.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - iZ_1308.Z5639 UbiA k141_1746_1 1288826.MSNKSG1_13257 5.57e-48 155.0 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,46733@72275|Alteromonadaceae 1236|Gammaproteobacteria G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992 MGS k141_1746_2 1288826.MSNKSG1_13262 3.38e-102 295.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,467Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_1746_3 1288826.MSNKSG1_13267 1.98e-230 634.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009333,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2414,iAPECO1_1312.APECO1_4131,iB21_1397.B21_02275,iBWG_1329.BWG_2176,iE2348C_1286.E2348C_2600,iEC042_1314.EC042_2623,iEC55989_1330.EC55989_2704,iECABU_c1320.ECABU_c27350,iECBD_1354.ECBD_1267,iECB_1328.ECB_02314,iECDH10B_1368.ECDH10B_2579,iECDH1ME8569_1439.ECDH1ME8569_2348,iECD_1391.ECD_02314,iECED1_1282.ECED1_2858,iECH74115_1262.ECH74115_3645,iECIAI1_1343.ECIAI1_2472,iECNA114_1301.ECNA114_2491,iECO103_1326.ECO103_2933,iECO111_1330.ECO111_3144,iECO26_1355.ECO26_3467,iECOK1_1307.ECOK1_2731,iECP_1309.ECP_2438,iECS88_1305.ECS88_2604,iECSE_1348.ECSE_2705,iECSF_1327.ECSF_2278,iECSP_1301.ECSP_3362,iECUMN_1333.ECUMN_2736,iECW_1372.ECW_m2643,iECs_1301.ECs3286,iEKO11_1354.EKO11_1314,iETEC_1333.ETEC_2527,iEcDH1_1363.EcDH1_1247,iEcHS_1320.EcHS_A2549,iEcSMS35_1347.EcSMS35_2569,iEcolC_1368.EcolC_1264,iG2583_1286.G2583_2946,iJO1366.b2414,iJR904.b2414,iLF82_1304.LF82_0418,iNRG857_1313.NRG857_12105,iSSON_1240.SSON_2503,iSbBS512_1146.SbBS512_E2766,iUMN146_1321.UM146_04550,iUMNK88_1353.UMNK88_3016,iUTI89_1310.UTI89_C2747,iWFL_1372.ECW_m2643,iY75_1357.Y75_RS12650,iZ_1308.Z3680 PALP k141_1746_4 1288826.MSNKSG1_13272 4.34e-53 167.0 COG5304@1|root,COG5304@2|Bacteria,1N269@1224|Proteobacteria,1SAZ0@1236|Gammaproteobacteria,46BER@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - CopG_antitoxin k141_1746_5 519989.ECTPHS_12778 6.38e-19 81.3 COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,1SD4N@1236|Gammaproteobacteria,1X1CI@135613|Chromatiales 135613|Chromatiales K Bacterial antitoxin of type II TA system, VapB - - - - - - - - - - - - VapB_antitoxin k141_8688_3 340099.Teth39_1865 5.24e-29 114.0 COG4923@1|root,COG4923@2|Bacteria,1UEUI@1239|Firmicutes,25JU1@186801|Clostridia,42I65@68295|Thermoanaerobacterales 186801|Clostridia S Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 k141_332_1 349124.Hhal_2433 3.93e-23 94.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales 135613|Chromatiales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_10052_1 756272.Plabr_2766 1.52e-46 164.0 COG1004@1|root,COG1004@2|Bacteria,2IXM4@203682|Planctomycetes 203682|Planctomycetes C Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_6555_1 501479.ACNW01000102_gene780 3.47e-58 200.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_2425_2 1472418.BBJC01000001_gene794 2.81e-58 181.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_19830_1 1234364.AMSF01000085_gene2962 6e-34 122.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1X6H1@135614|Xanthomonadales 135614|Xanthomonadales S Glutamyl-tRNA amidotransferase - - - ko:K09117 - - - - ko00000 - - - YqeY k141_19830_3 722419.PH505_bj00110 5.43e-64 205.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,2Q12T@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_20599_2 296591.Bpro_5550 3.56e-57 188.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,4A9SH@80864|Comamonadaceae 28216|Betaproteobacteria C NADH flavin oxidoreductase NADH oxidase - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_9352_1 243233.MCA0974 5.19e-18 78.2 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1XDSY@135618|Methylococcales 135618|Methylococcales P ZIP Zinc transporter - - - - - - - - - - - - - k141_9352_2 497321.C664_10742 1.26e-31 118.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KUES@206389|Rhodocyclales 206389|Rhodocyclales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_5188_1 269799.Gmet_1138 1.44e-36 132.0 COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,42Q1X@68525|delta/epsilon subdivisions,2WM75@28221|Deltaproteobacteria,43VDG@69541|Desulfuromonadales 28221|Deltaproteobacteria S Baseplate assembly protein - - - - - - - - - - - - - k141_3160_1 1286106.MPL1_07792 1.41e-213 599.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_3160_2 340.xcc-b100_3337 1.31e-125 377.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X55Q@135614|Xanthomonadales 135614|Xanthomonadales EH component I pabB - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_19201_2 270374.MELB17_20676 3.09e-191 540.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,464NP@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG5008 Tfp pilus assembly protein, ATPase PilU pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_16326_1 465817.ETA_18770 1.06e-18 82.4 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1S70H@1236|Gammaproteobacteria,3X6WE@551|Erwinia 1236|Gammaproteobacteria S Invasion gene expression up-regulator, SirB sirB2 - - - - - - - - - - - SirB k141_16326_2 292415.Tbd_0780 2.47e-75 230.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria 28216|Betaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_11503_1 1278309.KB907107_gene1732 8.42e-105 306.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,1XID0@135619|Oceanospirillales 135619|Oceanospirillales K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain degU - - - - - - - - - - - GerE,Response_reg k141_11503_2 1278309.KB907107_gene1733 2.73e-254 709.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XHPQ@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_21967_2 1278309.KB907101_gene677 4.9e-91 268.0 COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,1S4MZ@1236|Gammaproteobacteria,1XK3G@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_21967_3 1122599.AUGR01000031_gene15 5.68e-88 267.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XK7G@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_12204_1 686340.Metal_2185 2.01e-80 252.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1XDRB@135618|Methylococcales 135618|Methylococcales E PFAM Aminotransferase - - - - - - - - - - - - Aminotran_5 k141_14974_1 384765.SIAM614_10098 4.84e-25 102.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_14974_2 644107.SL1157_1356 1.74e-92 275.0 COG3090@1|root,COG3090@2|Bacteria,1R9XF@1224|Proteobacteria,2U6EU@28211|Alphaproteobacteria,4NCB3@97050|Ruegeria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter DctQ component - - - - - - - - - - - - DctQ k141_14974_3 384765.SIAM614_10108 3.36e-08 53.1 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria 28211|Alphaproteobacteria I conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct k141_15678_1 946235.CAER01000063_gene2374 3.86e-09 61.6 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,23K4N@182709|Oceanobacillus 91061|Bacilli K Bacterial transcription activator, effector binding domain - - - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_14254_1 335543.Sfum_2391 6.94e-96 300.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria 28221|Deltaproteobacteria V PFAM ABC transporter - - - ko:K01990,ko:K01992,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC2_membrane_3,ABC_tran k141_14254_2 1121405.dsmv_2633 5.52e-05 45.4 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MJGT@213118|Desulfobacterales 28221|Deltaproteobacteria M Biotin-lipoyl like - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 k141_349_1 1049564.TevJSym_ai00340 1.43e-174 512.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1J534@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_349_2 1026882.MAMP_01529 6.22e-22 93.6 COG0204@1|root,COG0204@2|Bacteria,1PDUQ@1224|Proteobacteria,1S51R@1236|Gammaproteobacteria,462J0@72273|Thiotrichales 72273|Thiotrichales I TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_5189_1 1037409.BJ6T_07570 2.33e-26 103.0 COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria,3JY5A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_5189_2 391624.OIHEL45_15719 6.71e-07 50.1 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_10071_1 2340.JV46_22530 1.3e-95 290.0 COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,1JBNA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_3,HlyD_D23,OEP k141_5919_1 396588.Tgr7_2339 1.41e-142 414.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1WX6X@135613|Chromatiales 135613|Chromatiales C Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_13569_1 1288826.MSNKSG1_10668 1.21e-33 122.0 COG1802@1|root,COG1802@2|Bacteria,1RIE7@1224|Proteobacteria,1S6K0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - FCD,GntR k141_13569_2 626887.J057_22635 6.13e-23 104.0 2FFR6@1|root,347NE@2|Bacteria,1P0S4@1224|Proteobacteria,1STKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13569_3 1288826.MSNKSG1_10678 1.06e-234 647.0 COG0392@1|root,COG0392@2|Bacteria,1R5YI@1224|Proteobacteria,1T0KN@1236|Gammaproteobacteria,46D10@72275|Alteromonadaceae 1236|Gammaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_13569_4 1288826.MSNKSG1_10683 0.0 1202.0 COG0438@1|root,COG1409@1|root,COG0438@2|Bacteria,COG1409@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,466AT@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 k141_16327_1 1215092.PA6_002_01080 1.07e-19 91.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YI04@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Cache domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_8697_1 1286106.MPL1_03900 9.36e-63 204.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,46095@72273|Thiotrichales 72273|Thiotrichales D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_8697_2 377629.TERTU_4181 6.41e-34 129.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,2PMZE@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Protein of unknown function, DUF484 yigA - - ko:K09921 - - - - ko00000 - - - DUF484 k141_8697_3 1249627.D779_3725 2.79e-133 385.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales 135613|Chromatiales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_19832_1 1288826.MSNKSG1_14197 1.85e-135 406.0 COG3055@1|root,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria,1RYPR@1236|Gammaproteobacteria,469I9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1929) - - - - - - - - - - - - DUF1929,Kelch_4 k141_15679_1 1335760.ASTG01000010_gene597 9e-14 73.6 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K2YM@204457|Sphingomonadales 204457|Sphingomonadales U Pilus formation protein N terminal region - - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N k141_1027_1 1278309.KB907099_gene3112 2.17e-18 82.8 COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,1RPH7@1236|Gammaproteobacteria,1XI23@135619|Oceanospirillales 135619|Oceanospirillales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.15 ko:K00455 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R03303 RC00643 ko00000,ko00001,ko00002,ko01000 - - - LigB k141_1027_2 1278309.KB907099_gene2508 1.01e-175 498.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria,1XR9V@135619|Oceanospirillales 135619|Oceanospirillales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_1027_3 1278309.KB907099_gene2510 6.23e-142 406.0 COG4340@1|root,COG4340@2|Bacteria,1PJYC@1224|Proteobacteria,1THCC@1236|Gammaproteobacteria,1XMNA@135619|Oceanospirillales 135619|Oceanospirillales S 2OG-Fe dioxygenase - - - - - - - - - - - - 2OG-Fe_Oxy_2 k141_1027_4 509635.N824_03075 2.31e-13 71.6 COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,1IS8S@117747|Sphingobacteriia 976|Bacteroidetes KT PFAM response regulator receiver - - - - - - - - - - - - Response_reg,SpoIIE k141_1027_5 1121935.AQXX01000139_gene3000 2.22e-81 265.0 COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S2RH@1236|Gammaproteobacteria,1XJB0@135619|Oceanospirillales 135619|Oceanospirillales T Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - - - - - - - - - - HD_5,Response_reg k141_1027_6 1122599.AUGR01000014_gene539 8.81e-91 270.0 COG2199@1|root,COG3706@2|Bacteria,1QX2V@1224|Proteobacteria,1T34Y@1236|Gammaproteobacteria,1XK8S@135619|Oceanospirillales 135619|Oceanospirillales T Helix-turn-helix domain - - - - - - - - - - - - HTH_17,Response_reg k141_1027_7 1232683.ADIMK_3505 4.04e-19 96.7 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CBS,EAL,GGDEF,PAS,PAS_4,PAS_9 k141_10072_1 1294143.H681_14070 1.84e-115 344.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.96 ko:K00128,ko:K20199 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00623,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00623,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01294,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11195 RC00047,RC00071,RC00075,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14255_1 95619.PM1_0226635 8.48e-22 92.4 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_14255_2 1026882.MAMP_01610 3.54e-33 123.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,45ZU9@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_6569_1 279238.Saro_3711 4.21e-06 54.7 COG1309@1|root,COG1309@2|Bacteria,1Q5ND@1224|Proteobacteria,2UQ9P@28211|Alphaproteobacteria,2K8VR@204457|Sphingomonadales 204457|Sphingomonadales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_6569_2 857087.Metme_1659 9.85e-62 195.0 COG2227@1|root,COG2227@2|Bacteria,1QYD8@1224|Proteobacteria,1T58X@1236|Gammaproteobacteria 1236|Gammaproteobacteria H ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_8073_1 1278309.KB907100_gene2237 4.14e-177 505.0 COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,1XI71@135619|Oceanospirillales 135619|Oceanospirillales C Thiol oxidoreductase - - - - - - - - - - - - DHOR k141_8073_2 1278309.KB907100_gene2236 2.28e-150 433.0 COG3487@1|root,COG3487@2|Bacteria,1MX5H@1224|Proteobacteria,1RPWE@1236|Gammaproteobacteria,1XHKC@135619|Oceanospirillales 135619|Oceanospirillales P Imelysin - - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_10815_1 1288826.MSNKSG1_15217 1.07e-158 454.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,46CFS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0477 Permeases of the major facilitator superfamily - - - ko:K08170 - M00702 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 - - MFS_1 k141_10815_2 1288826.MSNKSG1_15222 7.03e-105 306.0 COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,466Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane HA62_23750 - - - - - - - - - - - UPF0016 k141_10815_3 1288826.MSNKSG1_15227 3.49e-247 679.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,467JG@72275|Alteromonadaceae 1236|Gammaproteobacteria S ErfK YbiS YcfS YnhG family protein ycfS GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016807,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0034645,GO:0042546,GO:0042597,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070004,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K16291,ko:K19234,ko:K19235,ko:K19236 ko01503,map01503 - - - ko00000,ko00001,ko01002,ko01011 - - - LysM,YkuD k141_10815_4 1288826.MSNKSG1_15232 1.68e-174 487.0 COG0300@1|root,COG0300@2|Bacteria,1P42K@1224|Proteobacteria,1RS9E@1236|Gammaproteobacteria,464Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_19202_1 377629.TERTU_2112 5.89e-11 63.2 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,2PMWS@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L EXOIII dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_H,RNase_T k141_19202_2 519989.ECTPHS_12978 1.47e-101 308.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1WVYA@135613|Chromatiales 135613|Chromatiales H TIGRFAM molybdenum cofactor synthesis - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_13570_1 379066.GAU_3726 5.43e-21 92.8 COG3666@1|root,COG3666@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k141_3162_2 76114.ebA4463 1.44e-15 83.2 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,2KV67@206389|Rhodocyclales 206389|Rhodocyclales C FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_1028_1 1278309.KB907099_gene2760 1.84e-09 57.4 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RPU7@1236|Gammaproteobacteria,1XH5G@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_1028_2 1278309.KB907099_gene2759 2.46e-115 332.0 COG3090@1|root,COG3090@2|Bacteria,1RB5V@1224|Proteobacteria,1S3CS@1236|Gammaproteobacteria,1XJEN@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_17781_1 1288826.MSNKSG1_18360 4.21e-63 202.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,4647W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0516 DHBP_synthase,GTP_cyclohydro2 k141_17781_2 1288826.MSNKSG1_18355 8.11e-261 715.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,464V2@72275|Alteromonadaceae 1236|Gammaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 RibD_C,dCMP_cyt_deam_1 k141_17781_3 1288826.MSNKSG1_18350 5.09e-117 335.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,466Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_17781_4 1288826.MSNKSG1_18345 2.75e-305 832.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,4641N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_17781_5 1288826.MSNKSG1_18340 0.0 1080.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,464W9@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn k141_17781_6 1288826.MSNKSG1_18335 2.94e-314 858.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,4659K@72275|Alteromonadaceae 1236|Gammaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_17781_7 1288826.MSNKSG1_18330 2.1e-85 251.0 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,46894@72275|Alteromonadaceae 1236|Gammaproteobacteria S Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - - - - - - - - - - PilZ k141_17781_8 1288826.MSNKSG1_18325 1.39e-257 706.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,46563@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3734,iSBO_1134.SBO_4018 URO-D k141_17781_9 1288826.MSNKSG1_18320 0.0 961.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,464UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3503,iYL1228.KPN_03625 Fer4_11,Fer4_20,Pyr_redox_2 k141_17781_10 1288826.MSNKSG1_18315 0.0 2932.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,465BS@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0067 Glutamate synthase domain 1 gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_17781_11 1288826.MSNKSG1_18310 1.19e-78 251.0 COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,468KN@72275|Alteromonadaceae 1236|Gammaproteobacteria U Sporulation related domain damX GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR k141_11504_1 1123392.AQWL01000005_gene2862 6.14e-21 87.4 COG2920@1|root,COG2920@2|Bacteria,1N6BZ@1224|Proteobacteria,2WCAJ@28216|Betaproteobacteria,1KTBU@119069|Hydrogenophilales 119069|Hydrogenophilales P DsrC like protein - - - - - - - - - - - - DsrC k141_11504_2 3711.Bra024014.1-P 3.89e-07 53.9 29XB7@1|root,2RXRF@2759|Eukaryota,37TXK@33090|Viridiplantae,3GIAE@35493|Streptophyta,3I0BB@3699|Brassicales 35493|Streptophyta S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT k141_12205_2 199310.c3056 2.42e-235 654.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,3XMZ0@561|Escherichia 1236|Gammaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 k141_13571_1 1049564.TevJSym_bl00150 9.29e-62 203.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1J4S0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_15821_3 1212548.B381_02064 5.42e-07 52.4 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1Z1AD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG1045 Serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0840 Hexapep,SATase_N k141_3268_1 1288826.MSNKSG1_17733 0.0 1809.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,46403@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_5335_1 633131.TR2A62_2789 1.13e-91 283.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_464_1 1278309.KB907110_gene3204 6.43e-258 728.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1XIF3@135619|Oceanospirillales 135619|Oceanospirillales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_22052_1 1288826.MSNKSG1_07883 8.45e-17 76.3 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,4674N@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yceF GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_22052_2 1288826.MSNKSG1_07878 1.74e-123 352.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,46873@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-binding, possibly nucleic acid-binding protein yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 k141_22052_3 1288826.MSNKSG1_07873 1.42e-34 118.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,468BN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_22052_4 1288826.MSNKSG1_07868 2.19e-229 633.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,464HB@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695 FA_synthesis k141_22052_5 1288826.MSNKSG1_07863 5.48e-203 563.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,464BG@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k141_22052_6 1288826.MSNKSG1_07858 4.6e-73 224.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710 adh_short_C2 k141_15057_1 1121937.AUHJ01000009_gene1465 1.8e-29 119.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,465JD@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD linked oxidases, C-terminal domain - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_15057_2 1122604.JONR01000001_gene1715 4.9e-29 122.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1X9AC@135614|Xanthomonadales 135614|Xanthomonadales K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15057_3 292.DM42_5018 4.02e-25 111.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,2VR0E@28216|Betaproteobacteria,1KFID@119060|Burkholderiaceae 28216|Betaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_11588_1 1278309.KB907105_gene1419 7.61e-84 278.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_7416_1 290315.Clim_2516 5.83e-26 106.0 COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi 1090|Chlorobi S PFAM Rhomboid family protein - - - - - - - - - - - - Rhomboid k141_17152_1 237368.SCABRO_02538 2.21e-111 340.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2IXNK@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_465_1 1168034.FH5T_15140 6.53e-66 217.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia 976|Bacteroidetes M Psort location CytoplasmicMembrane, score 10.00 algI - - - - - - - - - - - MBOAT k141_18544_1 857087.Metme_3848 7.62e-20 85.1 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XEYS@135618|Methylococcales 135618|Methylococcales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 k141_6663_1 1255043.TVNIR_2988 2.21e-145 423.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA k141_3901_1 266809.PM03_08225 1.51e-132 398.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs coxL - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_20670_1 367336.OM2255_09326 1.37e-89 280.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_21393_3 234826.AM1300 3.18e-26 106.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,47F6S@766|Rickettsiales 766|Rickettsiales C Cytochrome c oxidase subunit III coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_13027_1 1123393.KB891316_gene1664 7.43e-21 90.5 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,1KSTY@119069|Hydrogenophilales 119069|Hydrogenophilales M YMGG-like Gly-zipper - - - - - - - - - - - - Gly-zipper_YMGG,OmpA k141_13027_2 236097.ADG881_1369 3.55e-48 164.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales 135619|Oceanospirillales D COG1192 ATPases involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_10185_1 287.DR97_3381 2.96e-53 187.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1YEZ2@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Signal transducing histidine kinase, homodimeric domain chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_10185_2 472759.Nhal_3350 5.86e-62 208.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1S0CW@1236|Gammaproteobacteria,1X2DN@135613|Chromatiales 135613|Chromatiales NT CheB methylesterase - - - ko:K06597 ko02020,map02020 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheB_methylest k141_15822_1 1449063.JMLS01000014_gene1632 4.89e-08 61.2 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,26QB8@186822|Paenibacillaceae 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_17897_1 1122197.ATWI01000009_gene1542 0.0 1001.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - HSDR_N,ResIII k141_22053_1 1408473.JHXO01000003_gene2576 1.45e-14 75.5 COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes 976|Bacteroidetes S 2-Nitropropane dioxygenase - - - - - - - - - - - - - k141_22053_2 1122225.AULQ01000002_gene548 8.71e-30 119.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k141_3270_1 1123514.KB905900_gene2093 2.22e-107 332.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,45ZUX@72273|Thiotrichales 72273|Thiotrichales L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_12338_1 1123393.KB891328_gene602 3.51e-60 202.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1KSXW@119069|Hydrogenophilales 119069|Hydrogenophilales F 5'-nucleotidase, C-terminal domain - - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C k141_1172_1 1215092.PA6_020_00580 1.11e-100 306.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1YFFD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Trypsin degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_5336_1 1249627.D779_0119 1.48e-44 155.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1WW3U@135613|Chromatiales 135613|Chromatiales T PFAM PhoH family protein - - - ko:K06217 - - - - ko00000 - - - PhoH k141_5336_2 396588.Tgr7_2292 4.29e-124 367.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_11589_1 1236976.JCM16418_2420 7.49e-24 104.0 COG2199@1|root,COG3706@2|Bacteria,1TSGN@1239|Firmicutes,4HED7@91061|Bacilli,26REP@186822|Paenibacillaceae 91061|Bacilli T diguanylate cyclase ydaM - - - - - - - - - - - GGDEF,PAS,PAS_9 k141_1840_1 1122599.AUGR01000002_gene3477 5.63e-108 326.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1XHBB@135619|Oceanospirillales 135619|Oceanospirillales C oxidase, subunit - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_1840_2 1122599.AUGR01000002_gene3476 2.57e-217 606.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria,1XII1@135619|Oceanospirillales 135619|Oceanospirillales C cytochrome d ubiquinol oxidase, subunit - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_1840_3 318161.Sden_1276 9.19e-12 58.9 COG4890@1|root,COG4890@2|Bacteria,1NGDQ@1224|Proteobacteria,1SGGW@1236|Gammaproteobacteria,2QD3R@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM membrane bound YbgT family protein ybgT GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019867,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0071944 1.10.3.14 ko:K00424 ko00190,ko02020,map00190,map02020 M00153 - - ko00000,ko00001,ko01000 3.D.4.3 - - YbgT_YccB k141_1840_4 1278309.KB907100_gene2223 2.5e-100 304.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RM90@1236|Gammaproteobacteria,1XHRT@135619|Oceanospirillales 135619|Oceanospirillales KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Sigma54_activat k141_19311_1 1485544.JQKP01000018_gene586 2.04e-09 56.6 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,44VU8@713636|Nitrosomonadales 28216|Betaproteobacteria S DJ-1/PfpI family - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_19311_2 1005395.CSV86_05472 3.22e-48 167.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yibQ - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_19311_3 105559.Nwat_0028 8.22e-173 497.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_13028_1 323261.Noc_2581 2.57e-77 246.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1WVWX@135613|Chromatiales 135613|Chromatiales CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_17898_1 634497.HAH_2800 2.36e-05 49.3 COG0589@1|root,arCOG02053@2157|Archaea,2XZ3J@28890|Euryarchaeota,23X20@183963|Halobacteria 183963|Halobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_1173_1 999550.KI421507_gene2985 9.39e-42 141.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_1173_2 89187.ISM_01710 3.52e-34 117.0 COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,46R4C@74030|Roseovarius 28211|Alphaproteobacteria J COG1841 Ribosomal protein L30 L7E rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_10186_1 349521.HCH_06299 1.8e-38 150.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_8 k141_17154_1 1415779.JOMH01000001_gene1020 1.76e-23 99.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1X665@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_17154_2 1122211.JMLW01000011_gene137 2.32e-16 76.3 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,1XKJK@135619|Oceanospirillales 135619|Oceanospirillales M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_18546_1 1120956.JHZK01000016_gene2185 7.79e-141 404.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria,1JQNE@119043|Rhodobiaceae 28211|Alphaproteobacteria EP N-terminal TM domain of oligopeptide transport permease C dppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02034,ko:K12370 ko02010,ko02024,map02010,map02024 M00239,M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_13712_1 207954.MED92_14243 2.34e-55 186.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHE8@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 ko:K00130,ko:K00151,ko:K10217 ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00555,M00569 R02565,R02566,R02762,R03889,R04418,R05353 RC00080,RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_13712_2 1122599.AUGR01000009_gene2305 7.24e-176 491.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1XHUJ@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase family - - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_14349_1 1232683.ADIMK_0265 7.26e-138 400.0 COG2207@1|root,COG2207@2|Bacteria,1R81X@1224|Proteobacteria,1S0CG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_14349_3 1278309.KB907104_gene857 9.84e-78 232.0 COG1539@1|root,COG1539@2|Bacteria,1RDHQ@1224|Proteobacteria,1S4Q3@1236|Gammaproteobacteria,1XKN1@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate folX - 5.1.99.7 ko:K07589 ko00790,map00790 - R11082 RC01479 ko00000,ko00001,ko01000 - - - FolB k141_14349_4 1278309.KB907104_gene855 9.77e-60 187.0 COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1S2VZ@1236|Gammaproteobacteria,1XJSF@135619|Oceanospirillales 135619|Oceanospirillales S DNA-binding protein VF530 - - - - - - - - - - - - VF530 k141_1860_2 396588.Tgr7_1140 4.36e-12 65.1 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1WWKH@135613|Chromatiales 135613|Chromatiales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_13056_2 1288826.MSNKSG1_17975 4.08e-76 230.0 COG2165@1|root,COG2165@2|Bacteria 2|Bacteria NU general secretion pathway protein - - - ko:K02457,ko:K10926 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl k141_20688_1 1255043.TVNIR_1098 1.62e-22 90.5 2CFFG@1|root,2ZJ1J@2|Bacteria,1P5Q0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_20688_2 765911.Thivi_4472 4.48e-40 139.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1WXNV@135613|Chromatiales 135613|Chromatiales C cytochrome - - - - - - - - - - - - Ni_hydr_CYTB k141_5360_1 1278309.KB907099_gene2575 0.0 959.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_5360_2 1278309.KB907099_gene2574 3.31e-60 207.0 COG4564@1|root,COG5000@1|root,COG4564@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1T35N@1236|Gammaproteobacteria,1XRT7@135619|Oceanospirillales 135619|Oceanospirillales T Cache_2 - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2 k141_3286_1 768670.Calni_1836 8.57e-33 129.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2GF7H@200930|Deferribacteres 200930|Deferribacteres T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_3286_2 596154.Alide2_2622 3.99e-53 181.0 COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,4AABZ@80864|Comamonadaceae 28216|Betaproteobacteria T GAF domain - - - - - - - - - - - - GAF,HD,HD_5 k141_19945_1 225937.HP15_2395 1.85e-125 367.0 COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,1RYTC@1236|Gammaproteobacteria,4675D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Spore coat polysaccharide biosynthesis protein - - - - - - - - - - - - Acetyltransf_3,Glyco_tran_28_C k141_5996_1 768710.DesyoDRAFT_3893 5e-17 81.3 COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,261W2@186807|Peptococcaceae 186801|Clostridia S integral membrane protein sdpI - - - - - - - - - - - DUF1648,SdpI k141_5996_2 264732.Moth_2084 8.14e-05 43.1 COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,42GZ1@68295|Thermoanaerobacterales 186801|Clostridia K Transcriptional regulator ArsR family - - - - - - - - - - - - HTH_20,HTH_5 k141_22060_1 1278309.KB907100_gene2162 9.92e-96 281.0 COG1507@1|root,COG1507@2|Bacteria,1RDW4@1224|Proteobacteria,1S5CM@1236|Gammaproteobacteria,1XKAI@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF501) - - - ko:K09009 - - - - ko00000 - - - DUF501 k141_22060_2 1278309.KB907100_gene2161 3.05e-57 177.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1XKGB@135619|Oceanospirillales 135619|Oceanospirillales C Ferredoxin - - - - - - - - - - - - Fer4 k141_22060_3 1278309.KB907100_gene2160 7.87e-92 270.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XJJM@135619|Oceanospirillales 135619|Oceanospirillales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_22060_4 1278309.KB907100_gene2159 3.2e-244 677.0 COG0501@1|root,COG0501@2|Bacteria,1QAMJ@1224|Proteobacteria,1S05I@1236|Gammaproteobacteria,1XHVB@135619|Oceanospirillales 135619|Oceanospirillales O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_22060_5 1122212.AULO01000012_gene1048 0.0 929.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1XIQA@135619|Oceanospirillales 135619|Oceanospirillales CH Phenol hydroxylase, C-terminal dimerisation domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_7440_1 105559.Nwat_0750 5.84e-162 469.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1WWHC@135613|Chromatiales 135613|Chromatiales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_19320_1 765911.Thivi_3744 3.9e-86 258.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1WWVC@135613|Chromatiales 135613|Chromatiales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_484_1 509635.N824_11410 5.39e-33 133.0 COG1511@1|root,COG1511@2|Bacteria,4PMPJ@976|Bacteroidetes,1IQJY@117747|Sphingobacteriia 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k141_7441_2 864051.BurJ1DRAFT_3340 3.36e-08 55.1 28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_10208_1 580332.Slit_2417 7.41e-32 126.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,44VK3@713636|Nitrosomonadales 28216|Betaproteobacteria S Peptidase family M48 yggG_1 - - - - - - - - - - - Peptidase_M48,TPR_19 k141_2527_1 1123401.JHYQ01000006_gene148 1.81e-64 220.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales 72273|Thiotrichales P heavy metal translocating P-type ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_2527_2 396588.Tgr7_2993 5.27e-19 79.7 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Cytochrome oxidase maturation protein ccoS - - - - - - - - - - - FixS k141_21407_1 712898.Pvag_2580 3.18e-12 66.2 COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,1RPUV@1236|Gammaproteobacteria,3VYRI@53335|Pantoea 1236|Gammaproteobacteria P Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system hmuV - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_21407_2 1278309.KB907109_gene3264 2.31e-87 265.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XIUS@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_1861_1 1123054.KB907710_gene893 3.09e-45 153.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1WW0K@135613|Chromatiales 135613|Chromatiales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_9449_1 391595.RLO149_c003450 2.75e-66 226.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2P3FF@2433|Roseobacter 28211|Alphaproteobacteria Q Zinc-dependent metalloprotease - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - HemolysinCabind,PPC,Peptidase_M10_C,Reprolysin_4 k141_18568_2 28229.ND2E_0412 9.36e-10 64.7 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,2Q62Q@267889|Colwelliaceae 1236|Gammaproteobacteria K PFAM response regulator receiver, regulatory protein LuxR tcsR - - - - - - - - - - - GerE,Response_reg k141_587_2 118163.Ple7327_0401 9.72e-145 422.0 COG1812@1|root,COG1812@2|Bacteria 2|Bacteria E S-adenosylmethionine synthetase (AdoMet synthetase) metK-2 - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_Synthase k141_20758_2 435908.IDSA_02685 1.64e-15 72.4 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,2QGFP@267893|Idiomarinaceae 1236|Gammaproteobacteria S YcgL domain-containing protein ycgL - - ko:K09902 - - - - ko00000 - - - YcgL k141_9576_1 518766.Rmar_2739 3.64e-25 108.0 COG1033@1|root,COG1033@2|Bacteria,4PIHC@976|Bacteroidetes,1FJ1U@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_2653_1 1380387.JADM01000001_gene182 1.79e-78 244.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XI08@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_2653_2 572477.Alvin_0525 6.05e-121 358.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_1968_1 1278309.KB907099_gene2783 1.39e-197 554.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XIS7@135619|Oceanospirillales 135619|Oceanospirillales E D-amino acid dehydrogenase dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_1968_2 1278309.KB907099_gene2782 9.96e-107 308.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1XJP7@135619|Oceanospirillales 135619|Oceanospirillales K AsnC family transcriptional regulator lrp - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_1968_3 1278309.KB907099_gene2781 9.68e-182 509.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1S242@1236|Gammaproteobacteria,1XRIK@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_5498_1 1288826.MSNKSG1_16121 2.31e-284 785.0 COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1RQZW@1236|Gammaproteobacteria,464FX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_5498_2 1288826.MSNKSG1_16116 9.06e-166 463.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,4669J@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain walR - - - - - - - - - - - Response_reg,Trans_reg_C k141_5498_4 1288826.MSNKSG1_16111 3.64e-218 601.0 COG3386@1|root,COG3386@2|Bacteria,1PHYJ@1224|Proteobacteria,1RX8E@1236|Gammaproteobacteria,46C5M@72275|Alteromonadaceae 1236|Gammaproteobacteria G SMP-30/Gluconolaconase/LRE-like region - - - - - - - - - - - - SGL k141_5498_5 1288826.MSNKSG1_16106 1.79e-65 207.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria,469BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_13194_1 999611.KI421504_gene692 4.57e-36 133.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2807V@191028|Leisingera 28211|Alphaproteobacteria O C-terminal, D2-small domain, of ClpB protein hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_13194_2 266809.PM03_13545 1.77e-28 113.0 COG0477@1|root,COG2814@2|Bacteria,1QUD1@1224|Proteobacteria,2TWB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_14468_1 1288826.MSNKSG1_04461 2.34e-226 641.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_14468_2 1288826.MSNKSG1_04466 4.98e-20 85.1 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,466NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO1391,iSDY_1059.SDY_2348 Cytidylate_kin k141_21539_1 1045856.EcWSU1_02248 3.52e-57 191.0 29GEV@1|root,303CN@2|Bacteria,1MXRD@1224|Proteobacteria,1RZBE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19429_1 1449350.OCH239_03605 5.28e-100 301.0 COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2TRYK@28211|Alphaproteobacteria,4KKDR@93682|Roseivivax 28211|Alphaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabF1 - - ko:K14660 - - - - ko00000,ko01000 - - - Ketoacyl-synt_C,ketoacyl-synt k141_16614_1 381666.PHG090 1.57e-72 223.0 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,2VJH8@28216|Betaproteobacteria,1K8ZF@119060|Burkholderiaceae 28216|Betaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit hoxY GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 ko:K18007 - - - - ko00000,ko01000 - - - Oxidored_q6 k141_16614_2 381666.PHG089 1.94e-124 359.0 COG3383@1|root,COG3383@2|Bacteria,1MXTC@1224|Proteobacteria,2WGYK@28216|Betaproteobacteria,1KIJI@119060|Burkholderiaceae 28216|Betaproteobacteria F 4Fe-4S single cluster domain hoxU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 ko:K18006 - - - - ko00000,ko01000 - - - Fer2_4,Fer4_15,NADH-G_4Fe-4S_3 k141_16614_3 266264.Rmet_1522 2.05e-301 838.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,1K4IR@119060|Burkholderiaceae 28216|Betaproteobacteria C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region hoxF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 ko:K18005 - - - - ko00000,ko01000 - - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB k141_18091_1 314271.RB2654_08052 8.13e-32 122.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_18091_2 1185766.DL1_05210 8.37e-42 148.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2XMFW@285107|Thioclava 28211|Alphaproteobacteria F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_2670_1 1255043.TVNIR_2420 3.7e-87 279.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.1,1.7.1.15 ko:K00362,ko:K05297 ko00071,ko00910,ko01120,map00071,map00910,map01120 M00530 R00787,R02000 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_15974_1 1461694.ATO9_05075 2.67e-29 108.0 COG3153@1|root,COG3153@2|Bacteria,1RD0C@1224|Proteobacteria,2U7AS@28211|Alphaproteobacteria,2PE7I@252301|Oceanicola 28211|Alphaproteobacteria S Acetyltransferase (GNAT) domain MA20_06530 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_9 k141_15974_2 991905.SL003B_1649 4.75e-27 104.0 COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,2TT7S@28211|Alphaproteobacteria,4BQFH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_11092_2 1298865.H978DRAFT_2369 2.7e-11 61.2 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,4687F@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif ppdD GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - ko:K02650,ko:K02682 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_8894_1 1500893.JQNB01000001_gene3285 1.25e-10 58.5 COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,1X6HZ@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox k141_8894_2 105559.Nwat_2339 1.15e-81 267.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales 135613|Chromatiales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_8330_1 1278309.KB907101_gene734 4.91e-51 166.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XJSZ@135619|Oceanospirillales 135619|Oceanospirillales E Lysine exporter protein (LysE - - - - - - - - - - - - LysE k141_8330_2 1278309.KB907101_gene735 3.08e-31 110.0 2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LITAF-like zinc ribbon domain containing protein - - - - - - - - - - - - Cys_rich_CPXG k141_18735_1 396588.Tgr7_0368 4.21e-68 218.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_12513_1 207954.MED92_01759 4.19e-39 140.0 COG3110@1|root,COG3110@2|Bacteria,1RK33@1224|Proteobacteria,1SACH@1236|Gammaproteobacteria,1XMQJ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0319 family - - - ko:K09909 - - - - ko00000 - - - DUF2057 k141_12513_2 1122599.AUGR01000013_gene740 8.74e-121 356.0 COG3203@1|root,COG3203@2|Bacteria,1NA7U@1224|Proteobacteria,1RPXP@1236|Gammaproteobacteria,1XIHX@135619|Oceanospirillales 135619|Oceanospirillales M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_12513_3 935557.ATYB01000010_gene347 9.14e-153 452.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,4B765@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_5499_1 925775.XVE_4880 5.91e-26 106.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales 135614|Xanthomonadales V Efflux pump membrane transporter - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_14469_1 1123518.ARWI01000001_gene582 3.51e-21 97.4 COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria,461TZ@72273|Thiotrichales 72273|Thiotrichales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_20768_1 317025.Tcr_1800 2.3e-66 211.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_20768_2 396588.Tgr7_3082 2.52e-168 477.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQPA@1236|Gammaproteobacteria,1X2CQ@135613|Chromatiales 135613|Chromatiales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_20768_3 555778.Hneap_0792 6.81e-80 246.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1SZ87@1236|Gammaproteobacteria,1X2J8@135613|Chromatiales 135613|Chromatiales P PFAM ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_10363_1 1158146.KB907133_gene116 3.68e-33 120.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity VY92_00625 - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_10363_2 395494.Galf_2476 2.62e-55 182.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,44W1J@713636|Nitrosomonadales 28216|Betaproteobacteria T PFAM HPP family protein - - - ko:K07168 - - - - ko00000 - - - CBS,HPP k141_15975_1 2340.JV46_15000 2.24e-64 210.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4U6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C,RhlB k141_1980_1 1288826.MSNKSG1_11977 1.33e-102 296.0 COG2010@1|root,COG2010@2|Bacteria,1RH1S@1224|Proteobacteria,1SDRE@1236|Gammaproteobacteria,468QM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2010 Cytochrome c, mono- and diheme variants - - - - - - - - - - - - Cytochrome_CBB3 k141_1980_2 1288826.MSNKSG1_11982 8.41e-280 765.0 COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,1RQ5G@1236|Gammaproteobacteria,465XF@72275|Alteromonadaceae 1236|Gammaproteobacteria E TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system - - - - - - - - - - - - Peripla_BP_6 k141_1980_3 1288826.MSNKSG1_11987 1.68e-73 236.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,465NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S 40-residue YVTN family beta-propeller repeat pedA - - - - - - - - - - - Cytochrom_D1,Lactonase k141_1980_4 1288826.MSNKSG1_11992 1.22e-162 456.0 COG1131@1|root,COG1131@2|Bacteria,1MX56@1224|Proteobacteria,1S0C7@1236|Gammaproteobacteria,466WS@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component pedB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1980_5 1288826.MSNKSG1_11997 1.69e-187 521.0 COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,1RNF7@1236|Gammaproteobacteria,4657I@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0842 ABC-type multidrug transport system, permease component pedC - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_1980_6 1288826.MSNKSG1_12002 2.8e-149 421.0 COG1116@1|root,COG1116@2|Bacteria,1MU6C@1224|Proteobacteria,1S584@1236|Gammaproteobacteria,46ATF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_19430_1 1031711.RSPO_c00041 1.57e-20 89.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VU41@28216|Betaproteobacteria,1K78A@119060|Burkholderiaceae 28216|Betaproteobacteria K Rrf2 family nsrR - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_19430_2 1122135.KB893138_gene1109 2.12e-13 67.4 COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,2U3P5@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N k141_13874_1 754477.Q7C_462 8.64e-137 404.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales 72273|Thiotrichales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_1337_1 1278309.KB907101_gene510 1.79e-11 63.5 COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,1XIPW@135619|Oceanospirillales 135619|Oceanospirillales O Peptidase family U32 - - - - - - - - - - - - Peptidase_U32 k141_1337_2 1411685.U062_00052 1.54e-28 110.0 COG3154@1|root,COG3154@2|Bacteria,1N6DG@1224|Proteobacteria,1SA52@1236|Gammaproteobacteria 1236|Gammaproteobacteria I lipid carrier protein - - - - - - - - - - - - SCP2 k141_1337_3 1278309.KB907099_gene2625 3.32e-144 421.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,1XIMX@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD k141_18092_1 1122921.KB898187_gene4537 3.72e-15 75.1 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,26UZF@186822|Paenibacillaceae 91061|Bacilli EI Allophanate hydrolase subunit 2 - - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_18092_2 225937.HP15_3147 3.53e-139 394.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,1RR1E@1236|Gammaproteobacteria,464DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1989) ycgI - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_18092_3 1479237.JMLY01000001_gene3654 3.65e-97 287.0 COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,4641M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1989) IV02_09290 - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_18736_1 367336.OM2255_11290 8.18e-112 351.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family soxA2 - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_597_2 400682.PAC_15709540 9.3e-34 130.0 COG0661@1|root,KOG1235@2759|Eukaryota,39P9X@33154|Opisthokonta,3CQUD@33208|Metazoa 33208|Metazoa S ABC1 family - - - - - - - - - - - - ABC1 k141_8896_1 395493.BegalDRAFT_3043 2.58e-43 148.0 COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria 1236|Gammaproteobacteria C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters nifU - - ko:K13819 - - - - ko00000 - - - Fer2_BFD,NifU,NifU_N k141_8896_2 580332.Slit_0804 3.49e-43 143.0 COG0316@1|root,COG0316@2|Bacteria,1MZTE@1224|Proteobacteria,2VUJT@28216|Betaproteobacteria,44WGU@713636|Nitrosomonadales 28216|Betaproteobacteria S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn k141_15171_1 1288826.MSNKSG1_10053 1.31e-104 305.0 2ED96@1|root,3375M@2|Bacteria,1QXX5@1224|Proteobacteria,1T3IY@1236|Gammaproteobacteria,46DDF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF642) - - - - - - - - - - - - DUF642,VPEP k141_15171_2 1288826.MSNKSG1_10058 1.75e-177 499.0 COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,1RYVT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive Ion channel - - - - - - - - - - - - MS_channel k141_2673_1 1177181.T9A_00070 7.04e-55 179.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1XJI9@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_14471_1 1163408.UU9_07159 1.39e-116 342.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_5501_1 1415754.JQMK01000007_gene1860 8.43e-33 125.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,46546@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB k141_5501_2 1288826.MSNKSG1_15442 2.61e-95 279.0 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,467F4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - 1.6.5.3 ko:K00127,ko:K00334 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_9590_1 349124.Hhal_1184 2.73e-26 106.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1WYR7@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 k141_9590_2 379731.PST_4072 6.78e-05 43.9 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,1Z3FW@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_9590_3 582744.Msip34_0158 1.96e-26 100.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria,2KP3R@206350|Nitrosomonadales 206350|Nitrosomonadales D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_9590_4 95619.PM1_0227005 4.68e-50 167.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_9590_5 477228.YO5_17740 2.48e-05 43.5 2AYFF@1|root,31QIN@2|Bacteria,1QN59@1224|Proteobacteria,1TG4M@1236|Gammaproteobacteria,1Z3I4@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11093_1 1049564.TevJSym_ar00460 1.65e-249 698.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1J589@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_3423_1 1318628.MARLIPOL_16364 3.68e-22 91.3 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,46701@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG3023 Negative regulator of beta-lactamase expression ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Amidase_2 k141_3423_2 519989.ECTPHS_06117 1.96e-28 117.0 COG3725@1|root,COG3725@2|Bacteria 2|Bacteria - - ampE GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 6.3.1.10 ko:K02227,ko:K03807 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - AmpE,CobD_Cbib k141_3423_3 1123392.AQWL01000003_gene417 7.02e-15 71.2 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2WGE2@28216|Betaproteobacteria,1KSQD@119069|Hydrogenophilales 119069|Hydrogenophilales G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_20769_2 580332.Slit_0300 6.33e-10 63.9 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,44VSW@713636|Nitrosomonadales 28216|Betaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_18737_1 765913.ThidrDRAFT_4145 4.78e-74 247.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWAU@135613|Chromatiales 135613|Chromatiales U Hydrophobe Amphiphile Efflux-1 (HAE1) - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_598_1 388739.RSK20926_11844 2.5e-06 47.8 2EPF7@1|root,33H1V@2|Bacteria,1NQBI@1224|Proteobacteria,2UNAS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_18093_1 472759.Nhal_3420 5.8e-133 405.0 COG1674@1|root,COG3266@1|root,COG1674@2|Bacteria,COG3266@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales 135613|Chromatiales D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_2674_1 395495.Lcho_2436 1.35e-23 96.3 COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,1KKUU@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Bacterial transcriptional repressor C-terminal - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_11,TetR_N k141_2674_2 1206101.AZXC01000014_gene622 8.56e-10 63.2 COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2GKEU@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - - ko:K01990,ko:K21397 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl k141_4812_1 1286106.MPL1_05884 2.89e-131 394.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales 72273|Thiotrichales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_14680_1 765911.Thivi_3168 2.91e-21 97.4 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales 135613|Chromatiales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_14680_2 519989.ECTPHS_07242 7.77e-238 668.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales 135613|Chromatiales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_14680_3 1453496.AT03_03480 1.3e-20 86.7 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_11198_1 1031711.RSPO_c01148 9.62e-11 64.3 28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,1K17Y@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_11198_2 360911.EAT1b_1951 6.89e-17 77.4 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HWWZ@91061|Bacilli,3WG4M@539002|Bacillales incertae sedis 91061|Bacilli K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_1423_1 1278309.KB907099_gene2613 0.0 1751.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,1XI5X@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG - 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_16764_1 1208323.B30_09563 4.38e-52 186.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,2TUMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S integral membrane protein mprF - 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 - - DUF2156,LPG_synthase_TM k141_13287_2 472759.Nhal_1532 2.02e-90 275.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales 135613|Chromatiales BQ PFAM histone deacetylase superfamily - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl k141_20260_1 345073.VC395_1468 1.74e-25 110.0 COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1Y33D@135623|Vibrionales 135623|Vibrionales T Histidine Phosphotransfer domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg k141_18152_1 1288826.MSNKSG1_05201 2.37e-124 356.0 COG1802@1|root,COG1802@2|Bacteria,1RIE7@1224|Proteobacteria,1S6K0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - FCD,GntR k141_9787_1 413816.BBJP01000010_gene699 0.000589 47.8 COG2391@1|root,arCOG05632@2157|Archaea,2XW2J@28890|Euryarchaeota,23S2N@183963|Halobacteria 183963|Halobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_20951_2 1196835.A458_10790 4.4e-05 45.4 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria,1Z2KI@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_21638_1 1278309.KB907105_gene1530 2.21e-233 647.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XH80@135619|Oceanospirillales 135619|Oceanospirillales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_12584_2 1168067.JAGP01000001_gene1731 3.36e-48 165.0 2AC0A@1|root,311I2@2|Bacteria,1RG7Y@1224|Proteobacteria,1S5RW@1236|Gammaproteobacteria,463D6@72273|Thiotrichales 72273|Thiotrichales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_18153_1 1121878.AUGL01000007_gene1196 2.56e-49 162.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_20261_1 2340.JV46_12860 2.13e-92 293.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1J58B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the aconitase IPM isomerase family acnB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415 Aconitase,Aconitase_2_N,Aconitase_B_N k141_2820_1 983545.Glaag_0586 1.89e-238 677.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_13288_1 1089439.KB902243_gene1286 2.96e-06 45.8 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,461CG@72273|Thiotrichales 72273|Thiotrichales J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_13288_2 391615.ABSJ01000049_gene1559 4.02e-41 137.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_13288_4 396588.Tgr7_2313 2.21e-07 49.3 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales 135613|Chromatiales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_17445_1 396588.Tgr7_2021 5.21e-31 114.0 COG0500@1|root,COG2226@2|Bacteria,1QWW2@1224|Proteobacteria,1T361@1236|Gammaproteobacteria,1WY3X@135613|Chromatiales 135613|Chromatiales Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_17445_2 1123392.AQWL01000006_gene709 1.37e-148 430.0 COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,2VRTH@28216|Betaproteobacteria,1KSIM@119069|Hydrogenophilales 119069|Hydrogenophilales C Domain of unknown function DUF302 - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_17445_3 713586.KB900536_gene2263 4.44e-35 126.0 COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_17445_4 123214.PERMA_0097 2.94e-11 70.9 COG2199@1|root,COG3706@2|Bacteria,2G51D@200783|Aquificae 200783|Aquificae T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_5609_1 1237149.C900_00887 2.1e-16 75.9 2FGH6@1|root,348D3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_5609_3 1408164.MOLA814_02474 5.94e-25 103.0 2ABEH@1|root,310VA@2|Bacteria,1NCY4@1224|Proteobacteria,2W3JY@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4145) - - - - - - - - - - - - DUF4145 k141_11223_2 511062.GU3_08000 3.76e-113 340.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1Y5PG@135624|Aeromonadales 135624|Aeromonadales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_17452_2 1049564.TevJSym_ap00580 2.52e-85 254.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1J746@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Thioredoxin-like [2Fe-2S] ferredoxin nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_16775_1 1122135.KB893166_gene3041 1.81e-133 396.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_16775_2 395963.Bind_3523 1.85e-22 96.3 COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria,3NCAQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria K PFAM regulatory protein GntR HTH - - - ko:K11475 - - - - ko00000,ko03000 - - - FCD,GntR k141_42_1 1227497.C491_19689 1.24e-25 111.0 COG0642@1|root,COG2202@1|root,COG3413@1|root,arCOG02348@1|root,arCOG02349@1|root,arCOG02350@1|root,arCOG08095@1|root,arCOG02276@2157|Archaea,arCOG02327@2157|Archaea,arCOG02334@2157|Archaea,arCOG02348@2157|Archaea,arCOG02349@2157|Archaea,arCOG02350@2157|Archaea,arCOG08095@2157|Archaea,2XTCA@28890|Euryarchaeota,23S6Z@183963|Halobacteria 183963|Halobacteria T COG2202 FOG PAS PAC domain - - - - - - - - - - - - BAT,GAF_2,HTH_10,PAS_3,PAS_4,PAS_8,PAS_9 k141_4919_1 1122194.AUHU01000007_gene232 6.13e-40 139.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,46810@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_4919_2 1385515.N791_13720 6.92e-59 195.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S2K0@1236|Gammaproteobacteria,1X321@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_18873_1 472759.Nhal_0412 4.74e-162 492.0 COG0247@1|root,COG0277@1|root,COG0437@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0437@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_4207_1 983545.Glaag_3147 3.05e-38 141.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae 1236|Gammaproteobacteria M zinc metalloprotease rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_4207_2 741091.Rahaq_4820 8.11e-08 54.7 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,3FI0G@34037|Rahnella 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_19564_1 292415.Tbd_0034 1.31e-51 194.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria 28216|Betaproteobacteria L PD-(D/E)XK nuclease superfamily addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_20984_1 582744.Msip34_1543 1.3e-20 93.2 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KKX6@206350|Nitrosomonadales 206350|Nitrosomonadales H Belongs to the folylpolyglutamate synthase family - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_20984_2 1335757.SPICUR_07200 9.43e-08 54.3 COG3147@1|root,COG3147@2|Bacteria,1MXHQ@1224|Proteobacteria,1RRKM@1236|Gammaproteobacteria,1WZKK@135613|Chromatiales 135613|Chromatiales D Sporulation related domain - - - ko:K03749 - - - - ko00000 - - - SPOR k141_8412_1 1121374.KB891585_gene2402 5.83e-108 318.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2797) LA2027 - - - - - - - - - - - DUF2797 k141_2829_1 95619.PM1_0201870 1.83e-59 187.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_3528_1 1278309.KB907110_gene3215 1.13e-39 134.0 2DNT0@1|root,32YZR@2|Bacteria,1QX2U@1224|Proteobacteria,1T34V@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_3528_2 1278309.KB907110_gene3214 1.29e-140 399.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XHKG@135619|Oceanospirillales 135619|Oceanospirillales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_3528_3 1278309.KB907110_gene3213 1.82e-94 282.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XHGU@135619|Oceanospirillales 135619|Oceanospirillales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_5629_2 1232430.CAVG010000145_gene1486 4.51e-37 144.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,4GXKP@90964|Staphylococcaceae 91061|Bacilli T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like k141_18874_1 36080.S2JRD1 5.87e-19 85.9 COG0166@1|root,KOG2446@2759|Eukaryota,38EWT@33154|Opisthokonta,3NW61@4751|Fungi,1GT3S@112252|Fungi incertae sedis 4751|Fungi G Phosphoglucose isomerase PGI1 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006098,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006739,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019682,GO:0019693,GO:0019752,GO:0031012,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0062039,GO:0062040,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_11894_1 413404.Rmag_0825 4.27e-32 117.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria,1J6FB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Nitroreductase family ycdI - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k141_11894_2 1121912.AUHD01000013_gene982 6.34e-07 52.0 COG3369@1|root,COG3369@2|Bacteria,4NSK8@976|Bacteroidetes,1I4X7@117743|Flavobacteriia 976|Bacteroidetes S zinc finger, CDGSH-type - - - - - - - - - - - - zf-CDGSH k141_1438_1 1123278.KB893544_gene4878 1.4e-09 65.1 COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,47JM4@768503|Cytophagia 976|Bacteroidetes CT Cyclic nucleotide-monophosphate binding domain - - - ko:K03301 - - - - ko00000 2.A.12 - - TLC,cNMP_binding k141_1438_2 225937.HP15_3231 2.6e-93 293.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,464VC@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family ybaL - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N k141_6304_2 370438.PTH_0142 3.73e-28 118.0 COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,26097@186807|Peptococcaceae 186801|Clostridia T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,Pkinase,Response_reg k141_8413_1 1347393.HG726020_gene1823 1.03e-06 46.6 2EIJX@1|root,33CB7@2|Bacteria,4NY82@976|Bacteroidetes,2FVGJ@200643|Bacteroidia,4ASM2@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k141_16776_1 1163408.UU9_05999 2.56e-38 142.0 COG2010@1|root,COG2010@2|Bacteria,1MW1W@1224|Proteobacteria,1S1DG@1236|Gammaproteobacteria,1X6MQ@135614|Xanthomonadales 135614|Xanthomonadales C SnoaL-like domain - - - - - - - - - - - - Cytochrome_CBB3,DUF4440 k141_13304_1 519989.ECTPHS_06977 6.46e-50 169.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1WWEM@135613|Chromatiales 135613|Chromatiales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_13304_2 1380387.JADM01000001_gene100 4.3e-10 60.1 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1XHAN@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N k141_20269_1 1121440.AUMA01000008_gene822 5.4e-35 127.0 COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,43AE6@68525|delta/epsilon subdivisions,2X6A8@28221|Deltaproteobacteria,2MH0U@213115|Desulfovibrionales 28221|Deltaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_9112_1 911045.PSE_4530 2.12e-33 139.0 COG3437@1|root,COG5001@1|root,COG3437@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg k141_4920_1 261292.Nit79A3_0611 2.38e-106 322.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2VKQG@28216|Betaproteobacteria,371QI@32003|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the glutamate synthase family glt - - - - - - - - - - - Glu_synthase k141_18875_1 1499686.BN1079_02952 9.98e-56 186.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphotransferase related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_16075_1 323848.Nmul_A1101 2.19e-07 49.7 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,373AA@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_16075_2 105559.Nwat_0565 4.41e-68 213.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S4ZA@1236|Gammaproteobacteria,1X25S@135613|Chromatiales 135613|Chromatiales C Belongs to the complex I subunit 6 family - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_3529_1 314345.SPV1_00345 5.66e-93 299.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_10509_1 1121937.AUHJ01000013_gene860 3.41e-17 81.3 COG0664@1|root,COG0664@2|Bacteria,1RKRH@1224|Proteobacteria,1S42Z@1236|Gammaproteobacteria,46BUZ@72275|Alteromonadaceae 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_10509_2 566466.NOR53_3412 1.85e-86 263.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1SXIG@1236|Gammaproteobacteria,1J7MC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_20985_1 748247.AZKH_1608 6.89e-29 111.0 COG1131@1|root,COG1131@2|Bacteria,1MX56@1224|Proteobacteria,2VQIQ@28216|Betaproteobacteria,2KXXS@206389|Rhodocyclales 206389|Rhodocyclales V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_20985_2 1278309.KB907099_gene2506 2.33e-115 338.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,1SYJZ@1236|Gammaproteobacteria,1XP4C@135619|Oceanospirillales 135619|Oceanospirillales P ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_20985_3 1278309.KB907099_gene2505 2.65e-51 168.0 COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,1RR15@1236|Gammaproteobacteria,1XJI6@135619|Oceanospirillales 135619|Oceanospirillales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_6305_1 89187.ISM_10685 1.11e-54 183.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,46Q1G@74030|Roseovarius 28211|Alphaproteobacteria E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases metB - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_6305_2 1122180.Lokhon_01261 2.51e-11 60.5 COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,2TUXK@28211|Alphaproteobacteria,2P7UY@245186|Loktanella 28211|Alphaproteobacteria F Acts on guanine, xanthine and to a lesser extent hypoxanthine gpt - 2.4.2.22 ko:K00769 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_4921_1 864051.BurJ1DRAFT_0167 2.25e-60 196.0 COG2770@1|root,COG2770@2|Bacteria,1QZYS@1224|Proteobacteria,2VJTC@28216|Betaproteobacteria,1KJFF@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365,HAMP k141_11895_1 640081.Dsui_3214 2.31e-51 189.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,2KUW5@206389|Rhodocyclales 206389|Rhodocyclales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_11225_1 1042209.HK44_007345 4.85e-150 434.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria 1236|Gammaproteobacteria O FeS assembly protein SufB sufB GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 k141_11225_2 948106.AWZT01000053_gene1578 3.03e-113 332.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria,1K5H7@119060|Burkholderiaceae 28216|Betaproteobacteria O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_7728_1 1288826.MSNKSG1_13752 1.71e-212 593.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,46495@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump VVA1228 - - - - - - - - - - - MatE k141_7728_2 1288826.MSNKSG1_13747 7.05e-116 332.0 COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,466K3@72275|Alteromonadaceae 1236|Gammaproteobacteria O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin k141_7728_3 1288826.MSNKSG1_13742 1.2e-103 310.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,467IV@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_5632_1 395493.BegalDRAFT_0456 1.02e-28 113.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,4610E@72273|Thiotrichales 72273|Thiotrichales K Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_5632_2 1122194.AUHU01000020_gene3494 5.5e-05 45.1 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_14706_1 1027273.GZ77_00285 0.0 1088.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XHCH@135619|Oceanospirillales 135619|Oceanospirillales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_20270_1 1123070.KB899247_gene1440 5.16e-56 189.0 COG1680@1|root,COG1680@2|Bacteria 2|Bacteria V peptidase activity - - - - - - - - - - - - Beta-lactamase k141_13987_1 1278309.KB907103_gene1068 4.61e-187 546.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHFD@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_13987_2 1278309.KB907103_gene1069 1.12e-70 218.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1XMCH@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09926 - - - - ko00000 - - - FixH k141_13987_3 1278309.KB907103_gene1070 6.15e-44 154.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1XI7X@135619|Oceanospirillales 135619|Oceanospirillales C COG0348 Polyferredoxin - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_12064_2 1123276.KB893257_gene2734 2.09e-15 79.3 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ccmG - - - - - - - - - - - AhpC-TSA,DUF4369 k141_15571_1 1120999.JONM01000002_gene834 1.4e-13 76.3 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,2KPXA@206351|Neisseriales 206351|Neisseriales N flagellar hook-associated protein - - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_7163_1 1288826.MSNKSG1_11943 2.29e-75 232.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,1RMM9@1236|Gammaproteobacteria,4655A@72275|Alteromonadaceae 1236|Gammaproteobacteria S May be involved in the transport of PQQ or its precursor to the periplasm pqqB GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 k141_7163_2 1288826.MSNKSG1_11938 2.07e-189 525.0 COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,1RP1V@1236|Gammaproteobacteria,4661W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 k141_7163_3 1288826.MSNKSG1_11933 1.1e-58 181.0 2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria,1SCEZ@1236|Gammaproteobacteria,468AS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Coenzyme PQQ synthesis protein D (PqqD) pqqD - - ko:K06138 - - - - ko00000 - - - PqqD k141_7163_4 1288826.MSNKSG1_11928 1.24e-278 761.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,4656E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyrroloquinoline quinone biosynthesis protein E pqqE GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_7163_5 1288826.MSNKSG1_11923 0.0 1206.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,465BC@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases pqqM - - - - - - - - - - - PD40,Peptidase_S9 k141_7163_6 1288826.MSNKSG1_11918 1.73e-270 741.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,4673A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1454 Alcohol dehydrogenase, class IV - - - - - - - - - - - - Fe-ADH k141_7163_7 1288826.MSNKSG1_11913 0.0 1070.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,1QTVB@1224|Proteobacteria,1T35F@1236|Gammaproteobacteria,469B9@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_8,PAS_9,Response_reg k141_7163_8 1288826.MSNKSG1_11908 1.24e-64 196.0 2C56U@1|root,34BH4@2|Bacteria,1P042@1224|Proteobacteria,1SS8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7163_9 1288826.MSNKSG1_11903 0.0 876.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,464A2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_7163_10 1288826.MSNKSG1_11898 6.24e-92 270.0 COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,1SASF@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG0575 CDP-diglyceride synthetase - - 2.7.7.67 ko:K19664 ko00564,map00564 - R08966 RC00002 ko00000,ko00001,ko01000 - - - CarS-like k141_7163_11 1288826.MSNKSG1_11893 1.78e-238 655.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 k141_7163_12 1288826.MSNKSG1_11888 9.88e-157 439.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,467HQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_7163_13 1288826.MSNKSG1_11883 3.69e-104 300.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,467FG@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_7163_14 1288826.MSNKSG1_11878 3.65e-31 110.0 COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,1SR7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_5826_1 929703.KE386491_gene630 2.2e-91 277.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia 976|Bacteroidetes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_5058_1 1118235.CAJH01000022_gene1394 3.17e-86 266.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1X32N@135614|Xanthomonadales 135614|Xanthomonadales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM k141_18318_1 225937.HP15_1351 6.24e-36 132.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,4655S@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-2 family transporter protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_18318_2 1167006.UWK_01404 9.16e-45 154.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales 28221|Deltaproteobacteria V PFAM ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_11391_1 1123360.thalar_01870 1.85e-29 115.0 COG5388@1|root,COG5388@2|Bacteria,1RCVG@1224|Proteobacteria,2U2IX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PAS domain - - - - - - - - - - - - PAS_5 k141_2261_1 1211814.CAPG01000088_gene4044 2.95e-05 45.1 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,1ZBSG@1386|Bacillus 91061|Bacilli I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_2261_2 765914.ThisiDRAFT_0274 1.81e-16 80.1 COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,1S2TH@1236|Gammaproteobacteria,1WY0K@135613|Chromatiales 135613|Chromatiales S PFAM Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_9923_1 1288826.MSNKSG1_05943 0.0 1022.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,469FR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_9923_2 1288826.MSNKSG1_05938 3.43e-168 480.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,468A1@72275|Alteromonadaceae 1236|Gammaproteobacteria G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_14148_1 1168067.JAGP01000001_gene2178 6.11e-91 284.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,463SJ@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_17631_1 1288826.MSNKSG1_07443 1.71e-120 365.0 COG0642@1|root,COG0784@1|root,COG3726@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3726@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,463ZD@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase sagS - 2.7.13.3 ko:K20973 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Response_reg k141_17631_2 1288826.MSNKSG1_07448 3.23e-101 294.0 COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,468SH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_17631_3 1288826.MSNKSG1_07453 3.01e-115 330.0 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,4671Y@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the glutathione peroxidase family - - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_17631_4 1288826.MSNKSG1_07458 2.8e-296 808.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,465JB@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_5059_1 714943.Mucpa_3998 2.42e-19 88.6 COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1IV25@117747|Sphingobacteriia 976|Bacteroidetes O Peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - Peptidase_S8 k141_8575_2 396588.Tgr7_2136 6.81e-46 151.0 COG4831@1|root,COG4831@2|Bacteria,1NMBS@1224|Proteobacteria,1SHJI@1236|Gammaproteobacteria,1X1V5@135613|Chromatiales 135613|Chromatiales S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_8575_3 396588.Tgr7_2135 3.05e-39 134.0 COG4831@1|root,COG4831@2|Bacteria,1N4ET@1224|Proteobacteria,1SG6W@1236|Gammaproteobacteria,1X1BI@135613|Chromatiales 135613|Chromatiales S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_8575_4 2340.JV46_26610 9.82e-41 136.0 COG4831@1|root,COG4831@2|Bacteria,1N55K@1224|Proteobacteria 1224|Proteobacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_16928_1 595460.RRSWK_00347 1.16e-38 135.0 COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes 203682|Planctomycetes K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - - - - - - - - - - Sigma70_ECF k141_2262_1 351348.Maqu_3841 2.44e-100 304.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465SI@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB GO:0001505,GO:0003674,GO:0003824,GO:0004029,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006113,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008802,GO:0009058,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015980,GO:0016043,GO:0016491,GO:0016620,GO:0016903,GO:0019285,GO:0019695,GO:0022607,GO:0031455,GO:0031456,GO:0034641,GO:0042133,GO:0042398,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097164,GO:1901564,GO:1901566,GO:1901576 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_0345,iECOK1_1307.ECOK1_0306,iECS88_1305.ECS88_0320,iECSF_1327.ECSF_0290 Aldedh k141_6455_1 1472418.BBJC01000001_gene403 1.41e-43 152.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria 28211|Alphaproteobacteria P transport system, permease component yejB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_6455_2 1123247.AUIJ01000012_gene855 2.94e-36 137.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type oligopeptide transport system periplasmic component yejA - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_20452_1 349521.HCH_01812 3.44e-48 176.0 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1R46H@1224|Proteobacteria,1S1DF@1236|Gammaproteobacteria,1XR47@135619|Oceanospirillales 135619|Oceanospirillales T HDOD domain - - - - - - - - - - - - HDOD,tRNA_edit k141_21169_2 83406.HDN1F_36200 1.55e-51 167.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1J66X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG1186 Protein chain release factor B yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_21169_4 237368.SCABRO_02538 1.02e-59 203.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2IXNK@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_17632_1 1049564.TevJSym_aw00360 1.42e-13 67.8 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfur oxidation protein SoxY soxY - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_17632_2 1049564.TevJSym_aw00370 1.17e-31 114.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1JAXW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur oxidation protein SoxZ soxZ - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ k141_2263_1 298386.PBPRB0650 2.19e-106 332.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XU9K@135623|Vibrionales 1224|Proteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism - - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_7880_1 351348.Maqu_0228 0.0 972.0 COG0457@1|root,COG0457@2|Bacteria,1QV4P@1224|Proteobacteria,1SJ0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K SIR2-like domain - - - - - - - - - - - - SIR2_2 k141_7880_2 1288826.MSNKSG1_16836 7.54e-139 399.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_7165_1 1278309.KB907100_gene1986 3.53e-188 530.0 COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1XIBP@135619|Oceanospirillales 135619|Oceanospirillales E O-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_7165_2 1278309.KB907100_gene1987 1.59e-10 60.8 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1XJD9@135619|Oceanospirillales 135619|Oceanospirillales P Reversible hydration of carbon dioxide yadF - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_21800_1 1288826.MSNKSG1_00686 3.2e-122 363.0 COG0840@1|root,COG0840@2|Bacteria,1PHEA@1224|Proteobacteria,1RX5Y@1236|Gammaproteobacteria,46B0P@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - HAMP,MCPsignal k141_21800_5 1288826.MSNKSG1_00666 2.89e-48 164.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria,466C4@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_19046_1 765911.Thivi_3170 1.15e-25 103.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_19046_2 1286106.MPL1_06844 3.02e-38 129.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,4611Y@72273|Thiotrichales 72273|Thiotrichales J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_16929_1 1122604.JONR01000005_gene971 3.75e-23 107.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1X5NA@135614|Xanthomonadales 135614|Xanthomonadales NU Neisseria PilC beta-propeller domain - - - - - - - - - - - - Neisseria_PilC k141_17633_1 519989.ECTPHS_06582 1.14e-71 239.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WXM6@135613|Chromatiales 135613|Chromatiales P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_2264_1 56780.SYN_02443 6.66e-31 116.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WNB6@28221|Deltaproteobacteria,2MS22@213462|Syntrophobacterales 28221|Deltaproteobacteria J Telomere recombination - - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_1595_1 105559.Nwat_3137 1.84e-107 319.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales 135613|Chromatiales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_1595_2 472759.Nhal_3953 1.06e-10 62.4 2DSZ4@1|root,33I02@2|Bacteria,1NGMX@1224|Proteobacteria,1SGFG@1236|Gammaproteobacteria,1X20S@135613|Chromatiales 135613|Chromatiales S ATP synthase I chain - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_1595_3 631362.Thi970DRAFT_04380 6.35e-73 228.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1WWUT@135613|Chromatiales 135613|Chromatiales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_20453_1 1266908.AQPB01000052_gene702 1.01e-111 334.0 COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_21801_2 1288826.MSNKSG1_02123 2.43e-96 284.0 COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,1S3DM@1236|Gammaproteobacteria,467DG@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_10683_1 1278309.KB907102_gene134 1.97e-233 644.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1XH3W@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_10683_2 1278309.KB907102_gene133 2.54e-35 126.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1XJEJ@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_17634_1 243233.MCA2446 1.2e-36 130.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XF7V@135618|Methylococcales 135618|Methylococcales M Belongs to the skp family - - - ko:K06142 - - - - ko00000 - - - OmpH k141_7177_2 398580.Dshi_1555 6.28e-34 123.0 COG1396@1|root,COG1396@2|Bacteria,1R6PS@1224|Proteobacteria,2TT0B@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 k141_7902_1 1212548.B381_15418 1.6e-06 49.3 COG0789@1|root,COG0789@2|Bacteria,1N9C6@1224|Proteobacteria,1SAI3@1236|Gammaproteobacteria,1Z2Z0@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_19717_1 1288826.MSNKSG1_06008 0.0 1305.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_19717_2 1288826.MSNKSG1_06013 1.2e-205 572.0 COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,1RW61@1236|Gammaproteobacteria,469JB@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - Glycos_transf_1 k141_12788_1 1131553.JIBI01000006_gene1085 3.86e-52 171.0 COG0454@1|root,COG0456@2|Bacteria,1RH4M@1224|Proteobacteria,2VWG3@28216|Betaproteobacteria,373CQ@32003|Nitrosomonadales 28216|Betaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k141_12081_1 635013.TherJR_0997 8.35e-42 167.0 COG0395@1|root,COG5001@1|root,COG5002@1|root,COG0395@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_8,PAS_9 k141_8588_1 765913.ThidrDRAFT_0905 2.28e-08 55.1 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1WW3V@135613|Chromatiales 135613|Chromatiales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL - 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_8588_2 1255043.TVNIR_3361 3.17e-47 157.0 2E8UR@1|root,33355@2|Bacteria,1MYPY@1224|Proteobacteria,1S6SI@1236|Gammaproteobacteria,1WYQ0@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_15582_1 748658.KB907312_gene1893 2.16e-65 219.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXKY@135613|Chromatiales 135613|Chromatiales T PFAM chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,NIT,PAS_3,PAS_8,PAS_9 k141_21191_1 880072.Desac_2354 1.56e-17 84.3 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2MS3W@213462|Syntrophobacterales 28221|Deltaproteobacteria S Smr domain - - - - - - - - - - - - Smr k141_2277_1 1380394.JADL01000007_gene4475 2.76e-35 124.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2UFK9@28211|Alphaproteobacteria,2JUAG@204441|Rhodospirillales 204441|Rhodospirillales S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_1619_1 589865.DaAHT2_1621 0.000221 52.0 COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM GGDEF domain containing protein - - - - - - - - - - - - GAF_2,GGDEF,HAMP k141_1619_2 395495.Lcho_0028 9.72e-47 155.0 COG0454@1|root,COG0456@2|Bacteria,1MZUT@1224|Proteobacteria,2VS6B@28216|Betaproteobacteria,1KNYN@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k141_1619_3 765913.ThidrDRAFT_1284 8.55e-83 250.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S42B@1236|Gammaproteobacteria,1X0T8@135613|Chromatiales 135613|Chromatiales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_1619_4 349521.HCH_03352 2.78e-34 124.0 COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,1RRMA@1236|Gammaproteobacteria,1XJ20@135619|Oceanospirillales 135619|Oceanospirillales E Transglutaminase/protease-like homologues - - - - - - - - - - - - Transglut_core k141_21824_1 1117647.M5M_16045 1.77e-47 167.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RQW0@1236|Gammaproteobacteria,1J885@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k141_17654_1 1198232.CYCME_2165 1.22e-39 139.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,460Y2@72273|Thiotrichales 72273|Thiotrichales M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_17654_2 1026882.MAMP_00009 1.96e-07 54.3 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,460ZY@72273|Thiotrichales 72273|Thiotrichales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_15668_1 2340.JV46_27040 2.84e-12 65.1 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1JARK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_10809_1 1288826.MSNKSG1_14697 7.04e-147 447.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,464X6@72275|Alteromonadaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_10809_2 1288826.MSNKSG1_14702 0.0 2321.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,465KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_10809_3 1288826.MSNKSG1_14707 1.17e-94 276.0 2D78S@1|root,32TNJ@2|Bacteria,1N0VB@1224|Proteobacteria,1SJD8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4864) - - - - - - - - - - - - DUF4864 k141_10809_4 1288826.MSNKSG1_14712 0.0 1101.0 COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,4645Z@72275|Alteromonadaceae 1236|Gammaproteobacteria L VRR_NUC - - - - - - - - - - - - VRR_NUC k141_9343_1 985054.JQEZ01000002_gene3596 7.84e-33 117.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,4NCKD@97050|Ruegeria 28211|Alphaproteobacteria K Transcriptional regulator, ArsR family - - - - - - - - - - - - HTH_20,HTH_5 k141_9343_2 1197906.CAJQ02000009_gene3530 2.39e-09 58.9 COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,3JWKP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Calcineurin-like phosphoesterase prp1 - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos k141_7309_1 906968.Trebr_2333 1.47e-07 61.6 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2J6FV@203691|Spirochaetes 203691|Spirochaetes T Adenylate guanylate cyclase catalytic domain protein - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_7309_2 472759.Nhal_3857 3e-104 319.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales 135613|Chromatiales J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_1026_1 349124.Hhal_1188 2.35e-56 189.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1WWM0@135613|Chromatiales 135613|Chromatiales P extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_1026_2 497321.C664_18854 1.16e-97 291.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2VJHT@28216|Betaproteobacteria,2KW66@206389|Rhodocyclales 206389|Rhodocyclales C PKHD-type hydroxylase - - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 k141_1026_3 870187.Thini_0957 4.95e-101 310.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,46058@72273|Thiotrichales 72273|Thiotrichales C FMN-dependent dehydrogenase lldD - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh k141_1026_4 1355374.JARU01000001_gene429 1.85e-06 50.8 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,42SBW@68525|delta/epsilon subdivisions,2YPT4@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_14966_3 284031.JNXD01000039_gene6256 9.98e-07 53.9 COG0789@1|root,COG0789@2|Bacteria,2GPCQ@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - MerR_1 k141_1756_2 1158182.KB905025_gene342 2.81e-54 182.0 COG1960@1|root,COG1960@2|Bacteria,1NDQ8@1224|Proteobacteria,1S0J8@1236|Gammaproteobacteria,1X2HK@135613|Chromatiales 135613|Chromatiales I Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_N k141_19824_2 207954.MED92_12871 4.02e-06 48.1 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_8068_1 1122137.AQXF01000005_gene1270 7.4e-45 148.0 2E42N@1|root,32YZ4@2|Bacteria,1NB0A@1224|Proteobacteria,2UHGU@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_11500_1 1469613.JT55_04755 2.16e-83 257.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,3FCV2@34008|Rhodovulum 28211|Alphaproteobacteria G Glycosyl hydrolase family 3 N terminal domain nagZ - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Glyco_hydro_3 k141_14247_1 153721.MYP_943 3.23e-32 116.0 COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47RT9@768503|Cytophagia 976|Bacteroidetes M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_14247_2 880071.Fleli_0734 2.04e-27 106.0 COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,47PPP@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 nlpD_1 - - - - - - - - - - - Peptidase_M23 k141_19195_1 1123514.KB905899_gene1276 2.56e-86 270.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - - - - - - - - - - - G6PD_C,G6PD_N k141_19195_2 395494.Galf_1906 1.54e-60 196.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,44VZS@713636|Nitrosomonadales 28216|Betaproteobacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_20594_1 1120965.AUBV01000008_gene2105 1.32e-25 97.4 2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,47S69@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_20594_2 688270.Celal_2638 3.08e-18 82.0 COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia,1F8Q3@104264|Cellulophaga 976|Bacteroidetes S COGs COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like mazG - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_3811_1 314232.SKA53_00724 1.36e-107 314.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria,2P8W5@245186|Loktanella 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family ycgM GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0008948,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0018773,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 3.7.1.20 ko:K16165 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R01085 RC00326,RC00446 ko00000,ko00001,ko01000 - - - FAA_hydrolase k141_18438_1 519989.ECTPHS_12983 1.23e-16 77.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1WWNN@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine - - 2.4.2.28,2.4.2.44 ko:K00772,ko:K19696 ko00270,ko01100,map00270,map01100 M00034 R01402,R09668 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_18438_2 1121935.AQXX01000112_gene5737 1.42e-61 196.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1XJQK@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_16337_3 1278309.KB907102_gene140 4.49e-164 461.0 COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,1S2BC@1236|Gammaproteobacteria,1XIRS@135619|Oceanospirillales 135619|Oceanospirillales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_16337_4 1278309.KB907102_gene141 0.0 1045.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XHUA@135619|Oceanospirillales 135619|Oceanospirillales C Sulfite reductase - - - - - - - - - - - - NIR_SIR,NIR_SIR_ferr k141_16337_5 1278309.KB907102_gene142 2.86e-94 276.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria,1XKEY@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF934 k141_16337_6 1278309.KB907102_gene143 3.35e-164 461.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1XIMU@135619|Oceanospirillales 135619|Oceanospirillales EH Reduction of activated sulfate into sulfite - - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_16337_7 1278309.KB907102_gene144 4.58e-79 248.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XHN1@135619|Oceanospirillales 135619|Oceanospirillales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_2435_1 1278309.KB907102_gene161 1.29e-117 341.0 COG0388@1|root,COG0388@2|Bacteria,1MXBR@1224|Proteobacteria,1RQ4Z@1236|Gammaproteobacteria,1XHKT@135619|Oceanospirillales 135619|Oceanospirillales S Carbon-nitrogen hydrolase - - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_2435_3 998674.ATTE01000001_gene1848 4.39e-114 346.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_2435_5 1278309.KB907102_gene162 2.12e-61 194.0 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,1S6VD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14270_1 1278309.KB907099_gene2695 1.07e-10 61.6 COG2025@1|root,COG2025@2|Bacteria,1MUQ5@1224|Proteobacteria,1RS2R@1236|Gammaproteobacteria,1XHQV@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein, alpha subunit - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_14270_2 1278309.KB907099_gene2696 2.28e-137 394.0 COG2086@1|root,COG2086@2|Bacteria,1N8JA@1224|Proteobacteria,1RP9A@1236|Gammaproteobacteria,1XHX8@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF k141_14270_3 1278309.KB907099_gene2697 3.21e-43 153.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XHUS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_7326_1 391616.OA238_c23680 1.46e-91 277.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TSVB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S succinylglutamate desuccinylase aspartoacylase eutE - 3.5.1.125 ko:K06987,ko:K15784 ko00260,ko01100,map00260,map01100 - R09801 RC00064,RC00300 ko00000,ko00001,ko01000 - - - AstE_AspA k141_1768_1 472759.Nhal_3565 1.5e-64 222.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Adenylate cyclase cyaA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365 Adenyl_cycl_N,Adenylate_cycl k141_6582_2 765912.Thimo_1468 6.65e-30 116.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1WW57@135613|Chromatiales 135613|Chromatiales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_10832_1 1208323.B30_07356 9.88e-90 276.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacC - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_12917_1 1177928.TH2_09879 8.89e-49 164.0 COG1573@1|root,COG1573@2|Bacteria,1RBA6@1224|Proteobacteria,2U60S@28211|Alphaproteobacteria 28211|Alphaproteobacteria L uracil-dna glycosylase - - - - - - - - - - - - UDG k141_12917_2 1082931.KKY_3619 2.76e-125 372.0 COG1694@1|root,COG1694@2|Bacteria,1MX3B@1224|Proteobacteria,2TUBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k141_20610_1 572477.Alvin_1100 1.62e-59 206.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_8087_1 1278309.KB907099_gene2574 9.76e-231 665.0 COG4564@1|root,COG5000@1|root,COG4564@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1T35N@1236|Gammaproteobacteria,1XRT7@135619|Oceanospirillales 135619|Oceanospirillales T Cache_2 - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2 k141_8087_2 1278309.KB907099_gene2573 3.42e-138 394.0 COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XJHD@135619|Oceanospirillales 135619|Oceanospirillales T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_8087_3 1232683.ADIMK_3629 9.29e-218 610.0 COG2252@1|root,COG2252@2|Bacteria,1QU00@1224|Proteobacteria,1T1JI@1236|Gammaproteobacteria,464UK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Xanthine uracil vitamin C permease - - - - - - - - - - - - Xan_ur_permease k141_5208_1 1278309.KB907101_gene812 1.05e-19 80.9 2BYTD@1|root,33P98@2|Bacteria,1NHI8@1224|Proteobacteria,1SJ15@1236|Gammaproteobacteria,1XMPZ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5208_2 1278309.KB907101_gene811 7.17e-132 377.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1XJ08@135619|Oceanospirillales 135619|Oceanospirillales K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K07690 ko02020,ko05133,map02020,map05133 M00477,M00697 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - GerE,Response_reg k141_5208_3 1278309.KB907101_gene810 1.21e-80 241.0 2D4ZG@1|root,32THX@2|Bacteria,1N08Z@1224|Proteobacteria,1S98S@1236|Gammaproteobacteria,1XKSK@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5208_4 1278309.KB907101_gene809 1.4e-80 249.0 COG1196@1|root,COG1196@2|Bacteria,1N4Q4@1224|Proteobacteria,1SAM5@1236|Gammaproteobacteria,1XMGU@135619|Oceanospirillales 135619|Oceanospirillales D Plasmid replication region DNA-binding N-term - - - - - - - - - - - - KfrA_N k141_9363_1 1278309.KB907106_gene1377 1.98e-88 266.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XJHK@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_9363_2 1278309.KB907106_gene1378 1.81e-205 571.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_9363_3 1278309.KB907106_gene1379 5.24e-126 363.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XJ9Q@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_9363_4 1278309.KB907106_gene1380 3.85e-32 113.0 2DSZK@1|root,33I2H@2|Bacteria,1NJWH@1224|Proteobacteria,1SJ2R@1236|Gammaproteobacteria,1XQJ2@135619|Oceanospirillales 135619|Oceanospirillales S FeoA - - - - - - - - - - - - FeoA k141_9363_5 1278309.KB907106_gene1381 0.0 1084.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1XHHW@135619|Oceanospirillales 135619|Oceanospirillales P transporter of a GTP-driven Fe(2 ) uptake system - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_9363_7 1278309.KB907106_gene1382 0.0 902.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1XHJB@135619|Oceanospirillales 135619|Oceanospirillales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_2436_1 1046724.KB889828_gene2914 5.04e-107 321.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4641G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_19217_1 1278309.KB907099_gene2538 1.73e-56 179.0 2EEMZ@1|root,338FW@2|Bacteria,1NF7F@1224|Proteobacteria,1SE9X@1236|Gammaproteobacteria,1XMCZ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_12224_1 2340.JV46_28590 7.46e-113 339.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,1J840@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iJN746.PP_2845 Amidohydro_1,Urease_alpha k141_12224_2 1458357.BG58_13385 6.37e-50 160.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2VSGJ@28216|Betaproteobacteria,1K8JZ@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta k141_12224_3 395961.Cyan7425_2271 2.15e-52 166.0 COG0831@1|root,COG0831@2|Bacteria,1G6KQ@1117|Cyanobacteria,3KI94@43988|Cyanothece 1117|Cyanobacteria E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_gamma k141_12224_4 399739.Pmen_0696 7.98e-44 155.0 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1S5QC@1236|Gammaproteobacteria,1YD9J@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD k141_18454_1 2340.JV46_17620 9.84e-170 495.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1J572@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Oligopeptidase A prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_3177_1 1288826.MSNKSG1_05641 1.41e-116 350.0 COG0515@1|root,COG0515@2|Bacteria,1MWEY@1224|Proteobacteria,1RQHW@1236|Gammaproteobacteria,465AS@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_3177_2 1288826.MSNKSG1_05646 0.0 899.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RMJR@1236|Gammaproteobacteria,465MF@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes bkdB - 2.3.1.168 ko:K09699 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R02662,R03174,R04097,R10998 RC00004,RC02727,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_3177_3 1288826.MSNKSG1_05651 2.26e-142 406.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,465NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit bkdA2 - 1.2.4.4 ko:K00167 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_12918_1 1123053.AUDG01000047_gene1854 1.83e-91 287.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1WWIW@135613|Chromatiales 135613|Chromatiales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_9364_1 743720.Psefu_3675 1.08e-72 235.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1YY60@136845|Pseudomonas putida group 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_17064_2 1278309.KB907100_gene2154 1.89e-147 416.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XH6V@135619|Oceanospirillales 135619|Oceanospirillales D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_7327_1 1217718.ALOU01000007_gene1259 1.48e-45 163.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,1KF02@119060|Burkholderiaceae 28216|Betaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_7327_2 1316936.K678_03914 1.37e-08 58.2 COG0346@1|root,COG1433@1|root,COG0346@2|Bacteria,COG1433@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2JS47@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_21975_1 1278309.KB907101_gene424 3.05e-54 176.0 COG1802@1|root,COG1802@2|Bacteria,1Q85H@1224|Proteobacteria,1RZ0B@1236|Gammaproteobacteria,1XIUR@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K15735 - - - - ko00000,ko03000 - - - FCD,GntR k141_21975_2 1278309.KB907101_gene425 6.26e-219 605.0 2CG84@1|root,2Z8GB@2|Bacteria,1MVXD@1224|Proteobacteria,1RQ5B@1236|Gammaproteobacteria,1XIVX@135619|Oceanospirillales 135619|Oceanospirillales C CsiD - - - ko:K15737 - - - - ko00000 - - - CsiD k141_21975_3 1278309.KB907101_gene426 3.86e-157 448.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria,1XJ2W@135619|Oceanospirillales 135619|Oceanospirillales S Catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate - - - ko:K15736 - - - - ko00000,ko01000 - - - DAO k141_16338_1 1123228.AUIH01000022_gene3128 1.83e-09 57.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1XKR5@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_16338_2 1042377.AFPJ01000032_gene2822 8.42e-48 156.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,467AE@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_16338_4 663321.REG_0356 1.44e-16 78.2 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,282YU@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k141_19218_1 1231190.NA8A_06614 4.74e-11 68.6 COG0747@1|root,COG2931@1|root,COG3210@1|root,COG3468@1|root,COG4625@1|root,COG4733@1|root,COG0747@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,1MU7T@1224|Proteobacteria,2TYEC@28211|Alphaproteobacteria,43R5X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria QU Cadherin-like beta sandwich domain - - - - - - - - - - - - Autotransporter,Cadherin-like k141_15700_1 323850.Shew_3275 2.92e-10 58.5 COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,1S22M@1236|Gammaproteobacteria,2QBQ7@267890|Shewanellaceae 1236|Gammaproteobacteria N CheC-like family cheX - - ko:K03409 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheX k141_15700_4 331678.Cphamn1_1741 4.6e-99 302.0 COG1808@1|root,COG1808@2|Bacteria,1FEKP@1090|Chlorobi 1090|Chlorobi S Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 k141_3178_1 644107.SL1157_0139 4.89e-107 323.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,4NAN1@97050|Ruegeria 28211|Alphaproteobacteria H Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_6696_1 1182590.BN5_00708 7.55e-17 81.6 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1YCZH@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_6696_2 105559.Nwat_2581 4.37e-34 128.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1WXFU@135613|Chromatiales 135613|Chromatiales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_500_1 1288826.MSNKSG1_11578 2.45e-284 781.0 COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,1T2N1@1236|Gammaproteobacteria,465DB@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - GIY-YIG,RNase_T,VRR_NUC k141_500_2 1318628.MARLIPOL_04235 2.56e-80 250.0 COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,1SVEG@1236|Gammaproteobacteria,46BGR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_2 k141_15856_1 90813.JQMT01000001_gene2048 6.32e-59 201.0 COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P k141_15856_2 215803.DB30_6771 8.07e-16 74.3 COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,42VV6@68525|delta/epsilon subdivisions,2WS0G@28221|Deltaproteobacteria,2Z1B1@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 k141_6018_1 1255043.TVNIR_3846 6.17e-79 251.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_1888_1 467661.RKLH11_641 6.21e-14 69.3 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,3ZGN4@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E ABC-type polar amino acid transport system, ATPase component bztD - 3.6.3.21 ko:K02028,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k141_1888_2 981384.AEYW01000001_gene1435 2.02e-29 111.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,4NCAT@97050|Ruegeria 28211|Alphaproteobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_1215_1 391615.ABSJ01000033_gene697 6.48e-127 378.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1J5H2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon k141_18597_1 382464.ABSI01000006_gene852 2.7e-186 565.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor preT - 1.2.7.1 ko:K00171,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_20,Fer4_6,PFOR_II,POR,POR_N,Pyr_redox_2,Pyr_redox_3,TPP_enzyme_C k141_17200_1 187272.Mlg_2779 8.95e-75 254.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1WW36@135613|Chromatiales 135613|Chromatiales E PFAM NAD-glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_12378_1 926559.JoomaDRAFT_2678 2.94e-22 98.6 COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia 976|Bacteroidetes K CRP FNR family transcriptional regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_4701_1 439493.PB7211_851 2.25e-13 73.9 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,4BQ0C@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_17942_1 292414.TM1040_0760 7.26e-49 170.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,4NBRH@97050|Ruegeria 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_17942_2 367336.OM2255_12847 5.12e-75 240.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_16501_1 1095769.CAHF01000022_gene324 1.34e-26 116.0 COG1716@1|root,COG2203@1|root,COG2206@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,476NW@75682|Oxalobacteraceae 28216|Betaproteobacteria T HD domain - - 3.1.4.17 ko:K01120 ko00230,map00230 - R00191,R01234 RC00296 ko00000,ko00001,ko01000 - - - FHA,GAF,HD,HD_5 k141_10235_1 1218352.B597_004290 1.77e-10 60.5 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1YZZ7@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K Transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k141_3935_1 472759.Nhal_0536 2.16e-133 394.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_10963_1 1288826.MSNKSG1_10633 2.81e-182 533.0 COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,465TG@72275|Alteromonadaceae 1236|Gammaproteobacteria N ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux k141_10963_2 1288826.MSNKSG1_10628 7.98e-199 553.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,465J0@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1889_1 1188256.BASI01000001_gene245 2.23e-47 162.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,3FCU0@34008|Rhodovulum 28211|Alphaproteobacteria EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k141_1889_2 296591.Bpro_1052 1.73e-11 65.5 COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,2VMF8@28216|Betaproteobacteria,4ACXY@80864|Comamonadaceae 28216|Betaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_20701_1 1085623.GNIT_1745 3.34e-17 82.4 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,4661M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted integral membrane protein (DUF2189) - - - - - - - - - - - - DUF2189 k141_14360_1 1122218.KB893653_gene748 0.000222 42.7 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,1JSX4@119045|Methylobacteriaceae 28211|Alphaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_14360_2 1402135.SUH3_04650 5.05e-53 176.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2TSJP@28211|Alphaproteobacteria,3ZUTX@60136|Sulfitobacter 28211|Alphaproteobacteria S 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM k141_8208_1 396588.Tgr7_0559 1.11e-55 186.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1WWYR@135613|Chromatiales 135613|Chromatiales S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA k141_8208_2 265072.Mfla_0499 2.01e-10 67.4 COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,2KKK5@206350|Nitrosomonadales 206350|Nitrosomonadales S Tetratricopeptide repeat - - - - - - - - - - - - SnoaL_3,TPR_16,TPR_17 k141_6020_1 717774.Marme_1983 7.03e-82 250.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XHES@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_8795_1 1278309.KB907099_gene2569 1.38e-34 128.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,1XJT7@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_8795_2 1278309.KB907099_gene2569 1.83e-77 243.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,1XJT7@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_6698_1 349521.HCH_06083 1.42e-138 403.0 COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XI1G@135619|Oceanospirillales 135619|Oceanospirillales G Sugar ABC transporter substrate-binding protein gtsA - - ko:K17315 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - SBP_bac_1,SBP_bac_8 k141_12379_2 1121918.ARWE01000001_gene1750 6.26e-07 56.6 COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,1R9AF@1224|Proteobacteria 1224|Proteobacteria Q Multicopper oxidase, type 2 ompB - - - - - - - - - - - ASH,Cu-oxidase_2,fn3 k141_8209_2 367336.OM2255_12075 3.5e-11 63.2 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria 28211|Alphaproteobacteria CP Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit nuoL2 - 1.6.5.3 ko:K00341,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_10964_1 713586.KB900536_gene2299 7.84e-137 405.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_1216_1 661367.LLO_1796 4.03e-104 317.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1JDP1@118969|Legionellales 118969|Legionellales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_15,TPR_16,TPR_7 k141_1216_2 225937.HP15_1370 7.01e-27 104.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_21426_1 644107.SL1157_2924 4.31e-101 297.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,4NAE3@97050|Ruegeria 28211|Alphaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_21426_2 999550.KI421507_gene1462 2.58e-14 72.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria 28211|Alphaproteobacteria FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA k141_2555_1 1278309.KB907101_gene457 3.08e-222 640.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTVB@1224|Proteobacteria,1RYDJ@1236|Gammaproteobacteria,1XRSZ@135619|Oceanospirillales 135619|Oceanospirillales T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg k141_2555_3 1278309.KB907101_gene460 9.89e-183 533.0 COG4564@1|root,COG5001@1|root,COG4564@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,Reg_prop,Y_Y_Y,dCache_2 k141_17201_1 1278309.KB907102_gene251 2.94e-239 677.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RPZD@1236|Gammaproteobacteria,1XHMC@135619|Oceanospirillales 135619|Oceanospirillales K Ribonuclease R winged-helix domain - - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_19336_1 1278309.KB907102_gene93 1.59e-100 318.0 COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales 135619|Oceanospirillales D Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 k141_19336_2 1278309.KB907102_gene92 1.95e-168 471.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1XIIM@135619|Oceanospirillales 135619|Oceanospirillales IQ reductase phbB - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k141_19336_3 1278309.KB907102_gene91 3.87e-253 702.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XHNU@135619|Oceanospirillales 135619|Oceanospirillales V MATE efflux family protein - - - - - - - - - - - - MatE k141_19336_4 1122599.AUGR01000007_gene1180 8.68e-22 86.3 COG1942@1|root,COG1942@2|Bacteria,1N7K1@1224|Proteobacteria,1SCSS@1236|Gammaproteobacteria,1XMFM@135619|Oceanospirillales 135619|Oceanospirillales S Tautomerase enzyme - - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase k141_19336_5 1278309.KB907108_gene1591 1.47e-108 315.0 COG3224@1|root,COG3224@2|Bacteria,1QUU7@1224|Proteobacteria,1S1S3@1236|Gammaproteobacteria,1XS7M@135619|Oceanospirillales 135619|Oceanospirillales S Antibiotic biosynthesis monooxygenase - - - ko:K09932 - - - - ko00000 - - - ABM k141_19336_6 1278309.KB907108_gene1592 1.54e-141 403.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RS6V@1236|Gammaproteobacteria,1XI4V@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase k141_13757_1 314345.SPV1_00095 8.36e-97 313.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_10238_1 1122614.JHZF01000014_gene2638 1.72e-11 58.9 2AJD5@1|root,319YN@2|Bacteria,1Q4GF@1224|Proteobacteria,2VAYM@28211|Alphaproteobacteria,2PEVZ@252301|Oceanicola 28211|Alphaproteobacteria S Bacterial aa3 type cytochrome c oxidase subunit IV - - - - - - - - - - - - COX4_pro_2 k141_10238_2 1123360.thalar_00330 2.08e-14 70.9 2BZ3T@1|root,315W2@2|Bacteria,1PV8U@1224|Proteobacteria,2U9KU@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_14362_1 991905.SL003B_3844 4.41e-10 61.2 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4BPRG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E TOBE domain ydcT - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 k141_22084_2 1122604.JONR01000003_gene1498 8.35e-63 216.0 28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,1S04D@1236|Gammaproteobacteria,1X51D@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_19968_1 28229.ND2E_2784 2.05e-88 273.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_19968_2 1116375.VEJY3_04390 3e-151 436.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XW4V@135623|Vibrionales 135623|Vibrionales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k141_4704_1 519989.ECTPHS_11832 4.96e-50 166.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1WWA2@135613|Chromatiales 135613|Chromatiales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_17946_1 472759.Nhal_1120 2.58e-73 244.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_3936_1 1122599.AUGR01000010_gene1058 3.57e-124 359.0 COG4176@1|root,COG4176@2|Bacteria,1QTTE@1224|Proteobacteria,1S03C@1236|Gammaproteobacteria,1XR6V@135619|Oceanospirillales 135619|Oceanospirillales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_3936_2 1121479.AUBS01000014_gene1174 1.52e-25 102.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2TRV8@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type proline glycine betaine transport systems periplasmic components proX - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_1891_1 243924.LT42_22150 1.22e-60 207.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase k141_1217_2 744979.R2A130_3418 1.52e-52 179.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM k141_16504_1 1304883.KI912532_gene3234 7.3e-61 213.0 COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_7,PAS_8,PAS_9,PilJ,Response_reg k141_19337_1 985054.JQEZ01000002_gene3523 4.08e-37 129.0 COG0350@1|root,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,2TV5U@28211|Alphaproteobacteria,4NC5M@97050|Ruegeria 28211|Alphaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 k141_19337_2 367336.OM2255_06875 3.56e-42 146.0 COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_16522_2 472759.Nhal_3344 2.16e-57 181.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02657 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_16522_3 1042377.AFPJ01000032_gene2822 5.35e-51 164.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,467AE@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_16522_4 1122244.AUGF01000003_gene926 5.92e-16 79.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,3NT3W@468|Moraxellaceae 1236|Gammaproteobacteria NT Two component signalling adaptor domain pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_16522_5 396588.Tgr7_2901 6.54e-151 461.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X29W@135613|Chromatiales 135613|Chromatiales NT chemotaxis - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_4719_1 1121374.KB891575_gene1457 1.7e-129 390.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_17973_1 1278309.KB907107_gene1639 1.23e-135 412.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1XK6W@135619|Oceanospirillales 135619|Oceanospirillales U haemagglutination activity domain - - - - - - - - - - - - DUF3739,Haemagg_act k141_15116_3 349163.Acry_3102 1.97e-20 87.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,2UBM6@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DSBA-like thioredoxin domain - - - ko:K07396 - - - - ko00000 - - - DSBA,Thioredoxin_5 k141_22103_1 314231.FP2506_04601 1.01e-51 179.0 COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria,2U0PC@28211|Alphaproteobacteria 28211|Alphaproteobacteria O ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS k141_22103_2 314262.MED193_10066 1.67e-38 139.0 COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,2TQM4@28211|Alphaproteobacteria,2P4I4@2433|Roseobacter 28211|Alphaproteobacteria K Transcriptional regulator, LacI family protein - - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_21451_1 1163408.UU9_10057 9.75e-67 211.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1X3GV@135614|Xanthomonadales 135614|Xanthomonadales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_21451_2 767434.Fraau_2737 1.55e-11 64.7 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1X432@135614|Xanthomonadales 135614|Xanthomonadales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_19356_1 1278309.KB907101_gene448 5.92e-51 171.0 COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,1RQK2@1236|Gammaproteobacteria,1XHXV@135619|Oceanospirillales 135619|Oceanospirillales S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_19356_2 1278309.KB907101_gene447 3.82e-108 316.0 COG1280@1|root,COG1280@2|Bacteria,1RF1D@1224|Proteobacteria,1S43Q@1236|Gammaproteobacteria,1XJPE@135619|Oceanospirillales 135619|Oceanospirillales E Threonine transporter RhtB - - - - - - - - - - - - LysE k141_19356_3 1278309.KB907101_gene446 3.63e-128 374.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria,1XJ6H@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_19356_4 1278309.KB907101_gene445 2.5e-135 387.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1XJ54@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_13775_1 1123368.AUIS01000003_gene1556 6.7e-26 103.0 COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,1RSEU@1236|Gammaproteobacteria,2NDCA@225057|Acidithiobacillales 225057|Acidithiobacillales G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 k141_13775_2 1279019.ARQK01000040_gene391 8.48e-37 130.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1WW4H@135613|Chromatiales 135613|Chromatiales J PFAM methyltransferase small - - - - - - - - - - - - MTS,MTS_N k141_9487_1 435908.IDSA_10435 1.73e-37 138.0 COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,1RRY0@1236|Gammaproteobacteria,2QFU8@267893|Idiomarinaceae 1236|Gammaproteobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_1912_1 644076.SCH4B_2864 1.69e-108 317.0 COG1738@1|root,COG1738@2|Bacteria,1MVQU@1224|Proteobacteria,2TRYN@28211|Alphaproteobacteria,4NA9S@97050|Ruegeria 28211|Alphaproteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage yhhQ GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046116,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072531,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1990397 - ko:K09125 - - - - ko00000 - - - Vut_1 k141_1912_2 412597.AEPN01000005_gene1469 2.01e-07 51.6 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2TS9C@28211|Alphaproteobacteria,2PVQ1@265|Paracoccus 28211|Alphaproteobacteria E Aminotransferase class I and II tyrB - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_20708_1 1278309.KB907099_gene2655 7.24e-272 748.0 COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,1S1JM@1236|Gammaproteobacteria,1XI18@135619|Oceanospirillales 135619|Oceanospirillales M Alginate export - - - - - - - - - - - - Alginate_exp k141_8937_1 1049564.TevJSym_ak00680 2.09e-72 233.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1J5GF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG1530 Ribonucleases G and E rng GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_18761_2 1288826.MSNKSG1_11158 1.14e-49 160.0 COG1846@1|root,COG1846@2|Bacteria,1RJEE@1224|Proteobacteria,1SBSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K MarR family - - - - - - - - - - - - MarR_2 k141_2695_1 207954.MED92_02833 2.03e-58 196.0 28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1XHY9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10400_1 1298593.TOL_0842 1.78e-45 165.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XI39@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein - - - ko:K07121 - - - - ko00000 - - - LppC k141_4835_1 765910.MARPU_06630 2.16e-103 323.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1WW3V@135613|Chromatiales 135613|Chromatiales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL - 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_5523_1 948106.AWZT01000001_gene5552 6.85e-29 117.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2VH8K@28216|Betaproteobacteria,1K1M3@119060|Burkholderiaceae 28216|Betaproteobacteria E PFAM serine dehydratase alpha chain sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_15189_1 314345.SPV1_10841 3.36e-103 305.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria 1224|Proteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_1367_1 1382306.JNIM01000001_gene667 2.35e-18 85.9 COG0520@1|root,COG0520@2|Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - - - - - - - - - - - Aminotran_5 k141_1367_2 1122137.AQXF01000006_gene851 5.06e-47 165.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C_2,Acyltransferase,PP-binding k141_7584_1 469610.HMPREF0189_01428 1.18e-28 118.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,1KJPV@119065|unclassified Burkholderiales 28216|Betaproteobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_14498_1 1437882.AZRU01000001_gene2127 1.16e-28 109.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,1YFU8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_14498_3 1279019.ARQK01000035_gene1554 4.54e-33 122.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13906_1 1318628.MARLIPOL_05015 3e-79 245.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,4650B@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_10401_2 323848.Nmul_A0175 2.28e-54 184.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,371T8@32003|Nitrosomonadales 28216|Betaproteobacteria C 4Fe-4S double cluster binding domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_20800_1 420662.Mpe_A0434 1.04e-05 48.1 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,1KJS5@119065|unclassified Burkholderiales 28216|Betaproteobacteria O Cytochrome c assembly protein ccsB - - - - - - - - - - - Cytochrom_C_asm k141_20800_2 1502852.FG94_01399 8.21e-48 178.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,472EW@75682|Oxalobacteraceae 28216|Betaproteobacteria O ResB-like family resB - - ko:K07399 - - - - ko00000 - - - ResB k141_11731_1 349124.Hhal_1183 1.48e-09 55.8 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SX58@1236|Gammaproteobacteria,1WZBH@135613|Chromatiales 135613|Chromatiales S TIGRFAM TIGR02449 family protein - - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_9627_1 1453498.LG45_11475 7.42e-72 232.0 COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia,2NUTS@237|Flavobacterium 976|Bacteroidetes S Deoxyribodipyrimidine photo-lyase-related protein - - - ko:K06876 - - - - ko00000 - - - DPRP k141_17334_1 1211817.CCAT010000071_gene1288 1.83e-32 129.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,36E0C@31979|Clostridiaceae 186801|Clostridia L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_11138_1 870187.Thini_1080 1.67e-21 91.3 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_1386_1 631362.Thi970DRAFT_01573 9.88e-100 305.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_1386_2 349521.HCH_01075 6.48e-18 81.6 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1XM56@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_1386_3 1123517.JOMR01000001_gene3 4.41e-17 75.9 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,461D2@72273|Thiotrichales 72273|Thiotrichales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_17346_1 666685.R2APBS1_0695 3.44e-41 144.0 COG1609@1|root,COG1609@2|Bacteria,1R9T6@1224|Proteobacteria,1SPK1@1236|Gammaproteobacteria,1XCEV@135614|Xanthomonadales 135614|Xanthomonadales K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 k141_11746_1 1288826.MSNKSG1_08918 2.24e-116 351.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,4645D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) aidA - - - - - - - - - - - DUF1302 k141_16015_2 519989.ECTPHS_06727 5.04e-192 547.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1WX9B@135613|Chromatiales 135613|Chromatiales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_16015_3 1335757.SPICUR_09310 1.31e-09 57.8 COG1938@1|root,COG3103@1|root,COG1938@2|Bacteria,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1WY3A@135613|Chromatiales 135613|Chromatiales T SH3 domain - - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_2711_1 153948.NAL212_2938 2.55e-167 488.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,371QC@32003|Nitrosomonadales 28216|Betaproteobacteria C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA k141_19465_1 672.VV93_v1c26760 4.25e-17 79.0 COG2197@1|root,COG2197@2|Bacteria,1R531@1224|Proteobacteria,1S18M@1236|Gammaproteobacteria,1XVDS@135623|Vibrionales 135623|Vibrionales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - ko:K04333 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - GerE k141_19465_2 1042377.AFPJ01000051_gene40 5.45e-41 140.0 2C2E6@1|root,2ZPXX@2|Bacteria,1N6U8@1224|Proteobacteria,1SEU1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S assembly protein CsgE csgE - - ko:K04337 - - - - ko00000,ko02044 - - - CsgE k141_19465_3 1279017.AQYJ01000024_gene963 3.77e-35 124.0 2DEP1@1|root,32U3R@2|Bacteria,1N4PQ@1224|Proteobacteria,1SBR1@1236|Gammaproteobacteria,46DMT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VIII secretion system (T8SS), CsgF protein csgF GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030312,GO:0030313,GO:0031975,GO:0042710,GO:0044010,GO:0044462,GO:0044464,GO:0044764,GO:0051704,GO:0071944 - ko:K04338 - - - - ko00000,ko02044 - - - CsgF k141_19465_4 1117647.M5M_08995 5.31e-138 398.0 COG1462@1|root,COG1462@2|Bacteria,1MVZM@1224|Proteobacteria,1RQ5F@1236|Gammaproteobacteria,1J5P7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Curli production assembly transport csgG GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0019867,GO:0022610,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0033036,GO:0042597,GO:0042710,GO:0042802,GO:0042886,GO:0044010,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0045184,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098552 - ko:K06214 - - - - ko00000,ko02044 - - - CsgG k141_16650_1 1288826.MSNKSG1_14977 1.86e-256 703.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_16650_2 1288826.MSNKSG1_14982 5.93e-179 501.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,465UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iJN746.PP_0110 UbiA k141_20814_2 160488.PP_4268 9.75e-46 150.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1YYT7@136845|Pseudomonas putida group 1236|Gammaproteobacteria L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_20814_3 1384056.N787_08025 1.16e-87 263.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1X30Z@135614|Xanthomonadales 135614|Xanthomonadales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_9645_1 1288826.MSNKSG1_13182 2.1e-82 267.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RX68@1236|Gammaproteobacteria,46688@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2203 FOG GAF domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3 k141_9645_2 1288826.MSNKSG1_13177 7.29e-67 218.0 COG5002@1|root,COG5002@2|Bacteria,1QWCR@1224|Proteobacteria 1224|Proteobacteria T signal transduction Histidine kinase - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_20037_1 1415774.U728_390 1.24e-16 83.2 COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes 1239|Firmicutes T Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - ko:K07814 - - - - ko00000,ko02022 - - - GGDEF,HD,HD_5,PAS_3,Response_reg k141_5547_1 1085623.GNIT_2693 3.69e-26 110.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,464U9@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_1387_1 643867.Ftrac_2829 8.25e-50 169.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - k141_11139_2 1288494.EBAPG3_20620 6.94e-34 123.0 COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,372T2@32003|Nitrosomonadales 28216|Betaproteobacteria J Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - CSD,Ribosomal_S30AE k141_3467_1 1279015.KB908467_gene494 8.73e-118 363.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1Y46M@135624|Aeromonadales 135624|Aeromonadales MU AAA domain exeA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 k141_13930_2 1198232.CYCME_0641 1.56e-134 390.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,460H9@72273|Thiotrichales 72273|Thiotrichales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_4856_1 1278309.KB907099_gene2650 3.15e-249 691.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIWJ@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_4856_2 1278309.KB907099_gene2651 5.52e-165 474.0 COG2010@1|root,COG2010@2|Bacteria,1MUF6@1224|Proteobacteria,1RP6Y@1236|Gammaproteobacteria,1XHGM@135619|Oceanospirillales 135619|Oceanospirillales C Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - - - - - - - - - - Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV k141_6191_1 768671.ThimaDRAFT_0605 6.43e-212 599.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WWEY@135613|Chromatiales 135613|Chromatiales C FAD linked oxidase - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_10432_1 89187.ISM_01525 2.09e-139 426.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,46QM9@74030|Roseovarius 28211|Alphaproteobacteria F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_17347_1 1236959.BAMT01000009_gene3352 1.01e-92 306.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KM5A@206350|Nitrosomonadales 206350|Nitrosomonadales L TIGRFAM ATP-dependent helicase HrpA - - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_2712_1 1384056.N787_07700 3.35e-117 355.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1X2YR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_20815_1 1535422.ND16A_1814 6.17e-112 363.0 COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Parallel beta-helix repeats - - - - - - - - - - - - Cu-oxidase_3 k141_9646_1 765914.ThisiDRAFT_1341 3.35e-40 138.0 2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria,1WYGK@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF1841) - - - - - - - - - - - - DUF1841 k141_1388_1 713586.KB900536_gene2174 1.13e-53 187.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1RQY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07710 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_8960_1 28042.GU90_07025 1.06e-12 68.9 COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DYM9@85010|Pseudonocardiales 201174|Actinobacteria C Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase - - 1.1.2.3,1.13.12.4 ko:K00101,ko:K00467 ko00620,ko01100,map00620,map01100 - R00196,R00319 RC00044,RC01312 ko00000,ko00001,ko01000 - - - FMN_dh k141_8960_2 1217714.F975_00075 2.29e-57 214.0 COG2206@1|root,COG3290@1|root,COG2206@2|Bacteria,COG3290@2|Bacteria,1QXG8@1224|Proteobacteria,1T4ZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Membrane-associated sensor domain - - - - - - - - - - - - HD_5,MASE3,PAS,PAS_9 k141_4857_1 186497.PF0729 1.11e-42 153.0 COG1145@1|root,COG1456@1|root,arCOG00958@2157|Archaea,arCOG06909@2157|Archaea 2157|Archaea C CO dehydrogenase/acetyl-CoA synthase delta subunit - - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - CdhD,Fer4,PAPS_reduct k141_16018_2 298386.PBPRB0650 1.41e-66 223.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XU9K@135623|Vibrionales 1224|Proteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism - - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_10433_1 1469613.JT55_13725 2.46e-43 141.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria,3FDBX@34008|Rhodovulum 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_16651_1 1323663.AROI01000023_gene1501 3.85e-86 263.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S3EV@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_11140_1 930171.Asphe3_19350 3.78e-24 94.4 COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,1W9QU@1268|Micrococcaceae 201174|Actinobacteria K AsnC family - - - - - - - - - - - - AsnC_trans_reg k141_11140_2 880070.Cycma_1378 5.45e-49 172.0 COG1292@1|root,COG1292@2|Bacteria,4NEIW@976|Bacteroidetes,47KFC@768503|Cytophagia 976|Bacteroidetes M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_6808_1 1286106.MPL1_11673 1.35e-88 275.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,45ZZV@72273|Thiotrichales 72273|Thiotrichales P PFAM CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_6808_2 483219.LILAB_28270 3.43e-07 55.5 COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2WNRU@28221|Deltaproteobacteria,2YU91@29|Myxococcales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - FHA,GGDEF,Yop-YscD_cpl k141_9647_1 395493.BegalDRAFT_1631 2.71e-126 372.0 COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,1RSFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C protein alpha chain nifD - 1.18.6.1 ko:K02586 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - Oxidored_nitro k141_19467_1 1192868.CAIU01000012_gene1355 4.95e-18 80.1 COG3822@1|root,COG3822@2|Bacteria,1MWPT@1224|Proteobacteria,2U2MB@28211|Alphaproteobacteria,43H7R@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S ABC-type sugar transport system, auxiliary component - - 5.3.1.15 ko:K09988 ko00040,map00040 - R01898 RC00516 ko00000,ko00001,ko01000 - - - Lyx_isomer k141_19467_2 367336.OM2255_11950 2.83e-84 254.0 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type branched-chain amino acid transport systems ATPase component - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_2713_1 999549.KI421513_gene745 6.7e-164 468.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2808W@191028|Leisingera 28211|Alphaproteobacteria H Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 k141_5549_1 674977.VMC_28360 2.68e-45 160.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XSDS@135623|Vibrionales 135623|Vibrionales P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_3468_1 522306.CAP2UW1_0889 1.14e-10 61.6 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,1KQ5E@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 k141_7594_1 1232683.ADIMK_0480 6.85e-213 601.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,4644B@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4962 Flp pilus assembly protein, ATPase CpaF tadA - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_7594_2 1439940.BAY1663_02255 6.05e-88 279.0 COG2199@1|root,COG4963@1|root,COG3706@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S6CE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG4963 Flp pilus assembly protein ATPase CpaE - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31 k141_7594_3 1205908.AKXW01000002_gene3185 6.25e-16 78.2 COG4961@1|root,COG4961@2|Bacteria,1PRDK@1224|Proteobacteria,1TC3B@1236|Gammaproteobacteria,1XYH0@135623|Vibrionales 135623|Vibrionales U TadE-like protein VP2414 - - - - - - - - - - - TadE k141_7594_4 1123020.AUIE01000027_gene4605 1.26e-13 72.0 COG4961@1|root,COG4961@2|Bacteria,1N8UM@1224|Proteobacteria,1TC7W@1236|Gammaproteobacteria,1YK0X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria U TadE-like protein - - - - - - - - - - - - TadE k141_7594_5 1318628.MARLIPOL_12729 1.01e-47 176.0 COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,46AQ4@72275|Alteromonadaceae 1236|Gammaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad k141_10434_1 83219.PM02_00780 1.84e-131 389.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,3ZVE2@60136|Sulfitobacter 28211|Alphaproteobacteria J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_20816_1 1163617.SCD_n00904 1.58e-88 293.0 COG2199@1|root,COG2200@1|root,COG5002@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WHDZ@28216|Betaproteobacteria 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_9 k141_11141_2 1442599.JAAN01000035_gene702 1.86e-53 175.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,1X353@135614|Xanthomonadales 135614|Xanthomonadales H UbiA prenyltransferase family - - - - - - - - - - - - HAD,UbiA k141_18777_1 272134.KB731326_gene296 2.06e-41 147.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_25,Methyltransf_31,Ubie_methyltran k141_19598_1 1278309.KB907100_gene2080 1.97e-56 179.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XKC8@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_19598_2 1278309.KB907100_gene2081 3.54e-152 439.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XHB6@135619|Oceanospirillales 135619|Oceanospirillales M transferase waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N k141_3582_1 1288826.MSNKSG1_09728 1.83e-56 187.0 COG1488@1|root,COG1488@2|Bacteria 2|Bacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_3582_2 1288826.MSNKSG1_09733 1.32e-34 118.0 COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria,46BR1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin k141_1476_1 1288826.MSNKSG1_03986 5.9e-195 541.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,4661I@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the KdsA family kdsA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_1476_2 1288826.MSNKSG1_03981 0.0 1079.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,4646Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3323,iPC815.YPO3377 CTP_synth_N,GATase k141_1476_3 1288826.MSNKSG1_03976 1.72e-225 627.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,465VG@72275|Alteromonadaceae 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_17494_1 1288826.MSNKSG1_05481 7.06e-107 322.0 COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria,46B77@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases ygcU - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_17494_2 1288826.MSNKSG1_05476 6.69e-88 272.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,46472@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_790_1 1288826.MSNKSG1_14837 1.25e-122 356.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,463ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein containing LysM domain lysM - - - - - - - - - - - LysM k141_790_2 1288826.MSNKSG1_14842 6.18e-55 182.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae 1236|Gammaproteobacteria LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_8454_1 1177181.T9A_03130 5.83e-19 90.1 COG4590@1|root,COG4590@2|Bacteria,1MW7Q@1224|Proteobacteria,1S6QR@1236|Gammaproteobacteria,1XS3D@135619|Oceanospirillales 135619|Oceanospirillales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - - k141_14745_1 1123368.AUIS01000036_gene90 9.71e-63 219.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - CHASE,CHASE8,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_9837_1 935567.JAES01000012_gene955 2.14e-19 85.1 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S6G7@1236|Gammaproteobacteria,1X6FR@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_9837_2 1123073.KB899241_gene3467 3.32e-37 131.0 COG1247@1|root,COG1247@2|Bacteria,1NC5U@1224|Proteobacteria,1SWEE@1236|Gammaproteobacteria,1X7B9@135614|Xanthomonadales 135614|Xanthomonadales M COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_2873_1 1288826.MSNKSG1_11668 3.65e-98 306.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4651T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_20337_1 1453501.JELR01000001_gene3138 1.69e-71 234.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,4653E@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans k141_20337_2 713586.KB900536_gene1641 6.36e-36 128.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1WXIA@135613|Chromatiales 135613|Chromatiales Q PFAM Isochorismatase - - - - - - - - - - - - Isochorismatase k141_70_1 472759.Nhal_3859 3.8e-18 83.2 COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,1S5RT@1236|Gammaproteobacteria,1X0MN@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1614) - - - - - - - - - - - - DUF1614 k141_70_2 1123399.AQVE01000013_gene312 8.03e-19 81.6 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,460WR@72273|Thiotrichales 72273|Thiotrichales S Fe-S metabolism associated domain - - - ko:K02426 - - - - ko00000 - - - SufE k141_15464_2 666685.R2APBS1_3496 2.8e-62 197.0 COG2820@1|root,COG2820@2|Bacteria,1QVR4@1224|Proteobacteria,1T2HJ@1236|Gammaproteobacteria,1X3C6@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile - - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - PNP_UDP_1 k141_14044_1 545276.KB898735_gene1302 4.5e-78 238.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1WX9I@135613|Chromatiales 135613|Chromatiales G Belongs to the ribulose-phosphate 3-epimerase family - - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_14044_2 1123517.JOMR01000001_gene1904 3.25e-48 159.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,4602N@72273|Thiotrichales 72273|Thiotrichales G TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_16825_1 1288826.MSNKSG1_09643 9.59e-119 364.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit phaA - 1.6.5.3 ko:K00341,ko:K05559 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,3.D.1 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_10553_2 998088.B565_0178 5.4e-96 281.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1Y4I9@135624|Aeromonadales 135624|Aeromonadales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_13361_1 472759.Nhal_3565 1.14e-60 216.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Adenylate cyclase cyaA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365 Adenyl_cycl_N,Adenylate_cycl k141_4949_1 1384054.N790_13260 1.31e-31 115.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales 135614|Xanthomonadales K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_4949_2 1116472.MGMO_120c00590 8.27e-47 163.0 COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane protein domain - - - - - - - - - - - - RDD k141_21060_1 1122137.AQXF01000006_gene749 4.47e-100 295.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S -glutamine - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_5704_1 266779.Meso_3887 7.73e-22 93.6 2C6BU@1|root,32S87@2|Bacteria,1QPTM@1224|Proteobacteria,2UZPX@28211|Alphaproteobacteria,43Q9N@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_14746_1 1163617.SCD_n02602 3.04e-21 97.1 COG2203@1|root,COG3437@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3850@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria 28216|Betaproteobacteria T metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - DUF3369,HD,HD_5,Response_reg k141_791_2 391616.OA238_c21390 3.01e-22 90.5 COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0822 NifU homolog involved in Fe-S cluster formation nifU - - - - - - - - - - - NifU_N k141_7056_2 1286106.MPL1_06672 1.73e-208 587.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,4605R@72273|Thiotrichales 72273|Thiotrichales O PFAM Peptidase family U32 - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_2874_1 1278307.KB906973_gene1281 4.85e-49 177.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,2QHE6@267894|Psychromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_12645_1 321846.PS417_24300 1.54e-09 56.2 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - - - - - - - - - - PilZ k141_12645_2 1120999.JONM01000025_gene3021 3.32e-25 105.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM Forkhead-associated protein - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_6360_1 754476.Q7A_2231 1.62e-77 243.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_4261_1 1278309.KB907107_gene1681 7.81e-13 65.9 28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1XJCP@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126,SHOCT k141_4261_2 207954.MED92_16780 1.33e-19 81.3 COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0270 family yheU - - ko:K09898 - - - - ko00000 - - - UPF0270 k141_4261_3 1278309.KB907107_gene1683 3.08e-98 289.0 COG4764@1|root,COG4764@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - SLT k141_4261_4 1278309.KB907107_gene1684 6.16e-188 540.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_18221_1 2340.JV46_21820 3.36e-24 92.4 2FDFA@1|root,345GY@2|Bacteria,1P1RR@1224|Proteobacteria,1SVK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18221_2 338963.Pcar_0432 1.02e-81 249.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,43UYD@69541|Desulfuromonadales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_18221_3 580332.Slit_2150 5.2e-121 355.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_18221_4 1249627.D779_2173 2.54e-22 93.2 COG0569@1|root,COG0569@2|Bacteria,1RDDX@1224|Proteobacteria,1S3ZR@1236|Gammaproteobacteria,1WY9A@135613|Chromatiales 135613|Chromatiales C TrkA-N domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_13362_1 1056495.Calag_1059 6.79e-15 72.4 COG0529@1|root,arCOG01040@2157|Archaea,2XQ81@28889|Crenarchaeota 28889|Crenarchaeota F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase k141_13362_2 102125.Xen7305DRAFT_00015260 2.01e-49 172.0 COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,3VK64@52604|Pleurocapsales 1117|Cyanobacteria P TIGRFAM chromate transporter, chromate ion transporter (CHR) family - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_10555_1 95619.PM1_0205775 3.03e-79 250.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_12646_1 95619.PM1_0220610 1.83e-35 137.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein VPA0491 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_3585_1 998674.ATTE01000001_gene97 2.35e-121 356.0 COG0583@1|root,COG0583@2|Bacteria,1PH2D@1224|Proteobacteria,1SWJH@1236|Gammaproteobacteria,463DB@72273|Thiotrichales 72273|Thiotrichales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_2875_1 2340.JV46_20130 2.14e-13 73.6 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1J6IQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G MOFRL family ttuD - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_7058_1 396588.Tgr7_2908 2.28e-60 192.0 COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,1SBYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Heptaprenyl diphosphate synthase component I - - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I k141_2170_1 1026882.MAMP_01970 2.69e-283 790.0 COG3968@1|root,COG3968@2|Bacteria,1QDHB@1224|Proteobacteria,1RS3B@1236|Gammaproteobacteria,4622Z@72273|Thiotrichales 72273|Thiotrichales S Glutamine synthetase type III N terminal - - - - - - - - - - - - GSIII_N,Gln-synt_C k141_18919_1 472759.Nhal_2148 2.06e-111 334.0 COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria 1236|Gammaproteobacteria A Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP rtcA GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 ko:K01974 - - - - ko00000,ko01000 - - - RTC,RTC_insert k141_792_1 1278309.KB907099_gene2467 1.66e-119 364.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XI1I@135619|Oceanospirillales 135619|Oceanospirillales L Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C - - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_792_2 1236973.JCM9157_186 1.85e-15 78.2 COG1840@1|root,COG1840@2|Bacteria,1TSKP@1239|Firmicutes,4HBH2@91061|Bacilli,1ZDRE@1386|Bacillus 91061|Bacilli P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 k141_6361_2 314278.NB231_01174 1.02e-20 97.4 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_20340_2 2340.JV46_22500 1.04e-105 310.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_7077_1 472759.Nhal_0715 7.73e-71 229.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales 135613|Chromatiales T PFAM MucB RseB - - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_7077_2 1177181.T9A_01857 7.56e-09 59.3 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1XM5C@135619|Oceanospirillales 135619|Oceanospirillales T Positive regulator of algM - - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_19623_1 713587.THITH_12235 1.72e-06 46.6 COG0695@1|root,COG0695@2|Bacteria 2|Bacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins VY92_02980 - 1.11.1.15 ko:K03386,ko:K03676 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Glutaredoxin,Redoxin k141_19623_2 572477.Alvin_1323 7.47e-35 130.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_10571_1 1046724.KB889872_gene2365 2.18e-64 208.0 COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S2MZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase zinc-ribbon domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_13369_1 1123368.AUIS01000011_gene1180 5.46e-15 75.5 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_13369_2 1123368.AUIS01000011_gene1183 2.2e-57 181.0 COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_13369_3 32042.PstZobell_19543 1.13e-39 139.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1Z0NF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3412,iSDY_1059.SDY_0027 AdoMet_dc k141_14769_2 1123401.JHYQ01000002_gene2806 1.77e-54 182.0 COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,1RRKZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 k141_810_1 880071.Fleli_3974 1.49e-33 134.0 COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,47KRW@768503|Cytophagia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k141_18945_1 243277.VC_0249 1.76e-06 55.1 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1SQKI@1236|Gammaproteobacteria,1Y2FD@135623|Vibrionales 135623|Vibrionales IQ AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_2192_2 1380358.JADJ01000011_gene204 5.66e-48 162.0 COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_1490_3 1288826.MSNKSG1_09108 6.72e-91 266.0 293UA@1|root,2ZR9K@2|Bacteria,1P60N@1224|Proteobacteria,1SVZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_1490_4 1288826.MSNKSG1_09103 1.1e-289 793.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,4644Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_10572_1 443152.MDG893_00737 3.44e-24 101.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,464JE@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_10572_2 396588.Tgr7_1335 8.55e-07 50.4 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1WVWU@135613|Chromatiales 135613|Chromatiales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_16127_1 765911.Thivi_4336 8.1e-85 271.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1X2PK@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c k141_16127_2 1411685.U062_00524 3.61e-55 188.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1J5QT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_4966_2 443144.GM21_0437 1.26e-50 169.0 2B4XH@1|root,32REP@2|Bacteria,1PXEZ@1224|Proteobacteria,4305C@68525|delta/epsilon subdivisions,2WVH5@28221|Deltaproteobacteria,43UUP@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_4966_3 1177154.Y5S_01714 4.17e-104 324.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1XQ5M@135619|Oceanospirillales 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_811_1 1116375.VEJY3_21641 7.71e-34 119.0 2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_811_2 1415778.JQMM01000001_gene2178 8.08e-51 167.0 COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_18946_1 572477.Alvin_0357 1.11e-31 123.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_2351_2 1144932.ATTF01000016_gene1120 1.41e-14 67.8 COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2UC3F@28211|Alphaproteobacteria,4BSTE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G SAF domain - - 4.4.1.24 ko:K16845 ko00270,map00270 - R07633 RC01785 ko00000,ko00001,ko01000 - - - SAF k141_7268_1 1288826.MSNKSG1_01408 1.15e-136 390.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,466XD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 NUDIX,NUDIX-like,zf-NADH-PPase k141_12146_1 997884.HMPREF1068_02580 6.85e-56 187.0 COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,2FMQH@200643|Bacteroidia,4AKP1@815|Bacteroidaceae 976|Bacteroidetes E Psort location Cytoplasmic, score 8.96 aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph k141_14222_1 1415779.JOMH01000001_gene1319 1.16e-22 99.4 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1X6CK@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretion system protein C - - - - - - - - - - - - PDZ_2,T2SSC k141_13517_1 519989.ECTPHS_13183 5.14e-51 171.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1WWB2@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_6512_1 1122201.AUAZ01000039_gene3283 4.74e-69 218.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,465WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the precorrin methyltransferase family cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303,ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_10771_1 744979.R2A130_3267 1.28e-83 255.0 COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2TWFW@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_17733_1 1278309.KB907109_gene3297 7.42e-123 360.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XIRD@135619|Oceanospirillales 135619|Oceanospirillales CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_2373_2 706587.Desti_1512 1.92e-34 122.0 COG0640@1|root,COG0640@2|Bacteria,1Q62E@1224|Proteobacteria,4329P@68525|delta/epsilon subdivisions,2WYD0@28221|Deltaproteobacteria 28221|Deltaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 k141_3789_1 1318628.MARLIPOL_05145 3.89e-109 329.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 k141_3789_3 574966.KB898654_gene1142 3.21e-55 178.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1XJQ3@135619|Oceanospirillales 135619|Oceanospirillales F ADP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX,Nudix_N_2 k141_17009_1 89187.ISM_03245 4.24e-45 152.0 COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2TU2T@28211|Alphaproteobacteria,46PWJ@74030|Roseovarius 28211|Alphaproteobacteria S Calcineurin-like phosphoesterase MA20_22045 - - ko:K06953 - - - - ko00000 - - - Metallophos k141_17009_2 388401.RB2150_07243 2.78e-67 211.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,3ZG16@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_16294_1 396588.Tgr7_0578 2.82e-118 357.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1WW0Q@135613|Chromatiales 135613|Chromatiales EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_8023_2 1298593.TOL_3709 2.64e-34 123.0 COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,1T4IH@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Domain of unknown function (DUF1924) - - - - - - - - - - - - DUF1924 k141_10786_1 1288826.MSNKSG1_06348 6.4e-237 660.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,465NM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0155 Sulfite reductase, beta subunit (hemoprotein) cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_19156_1 472759.Nhal_3355 1.43e-80 246.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales 135613|Chromatiales V PFAM ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_8650_1 1123399.AQVE01000002_gene2486 6.87e-112 341.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4600X@72273|Thiotrichales 72273|Thiotrichales V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_12859_1 349124.Hhal_1478 6.16e-65 210.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales 135613|Chromatiales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_13522_2 338969.Rfer_0173 6.95e-32 115.0 COG3874@1|root,COG3874@2|Bacteria,1N4RT@1224|Proteobacteria 1224|Proteobacteria S Sporulation protein YtfJ (Spore_YtfJ) - - - - - - - - - - - - Spore_YtfJ k141_13522_3 338969.Rfer_0174 3.91e-23 98.6 2E21G@1|root,32X98@2|Bacteria,1N21H@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2953) - - - - - - - - - - - - DUF2953 k141_13522_5 426355.Mrad2831_0446 2.71e-16 80.1 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_999_1 287.DR97_5021 2.94e-18 88.2 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YD64@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_14934_2 1122194.AUHU01000014_gene1192 1.94e-314 872.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,464EW@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_14934_3 1042375.AFPL01000032_gene1023 5.28e-303 831.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_14934_4 994479.GL877882_gene6856 1.34e-24 101.0 COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4E94J@85010|Pseudonocardiales 201174|Actinobacteria G HpcH/HpaI aldolase/citrate lyase family - - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_301_1 666509.RCA23_c25880 1.18e-32 117.0 2CXG1@1|root,32T1W@2|Bacteria,1MZFE@1224|Proteobacteria,2UCTB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_301_2 367336.OM2255_10286 2.67e-42 145.0 COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,2TRU7@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the precorrin methyltransferase family cobM - 2.1.1.133,2.1.1.271 ko:K05936 ko00860,ko01100,map00860,map01100 - R05181,R05810 RC00003,RC01294,RC02049 ko00000,ko00001,ko01000 - - - TP_methylase k141_19798_1 768671.ThimaDRAFT_4172 7.87e-60 195.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales 135613|Chromatiales C PFAM Radical SAM - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_5881_1 519989.ECTPHS_02976 5.67e-94 287.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_5881_2 561231.Pecwa_0274 2.45e-39 139.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1MQUV@122277|Pectobacterium 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_3121_1 1123514.KB905899_gene1276 9.06e-115 347.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - - - - - - - - - - - G6PD_C,G6PD_N k141_12160_1 1278309.KB907104_gene950 1.68e-66 204.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1XJKM@135619|Oceanospirillales 135619|Oceanospirillales J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_12160_2 1278309.KB907104_gene949 4.38e-316 864.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XI3Y@135619|Oceanospirillales 135619|Oceanospirillales T Response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes glnG - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_12160_3 1278309.KB907104_gene948 6.43e-224 620.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1XHHE@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8 k141_12160_4 1278309.KB907104_gene946 0.0 907.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1XHVZ@135619|Oceanospirillales 135619|Oceanospirillales E highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_12160_5 1278309.KB907104_gene945 1.98e-291 805.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1XIIQ@135619|Oceanospirillales 135619|Oceanospirillales T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_6532_1 388401.RB2150_16142 3.53e-121 360.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria 28211|Alphaproteobacteria CP Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit nuoL2 - 1.6.5.3 ko:K00341,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_6532_2 571166.KI421509_gene3637 9.38e-09 57.8 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria CP Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit nuoN2 - 1.6.5.3 ko:K00343,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M k141_11464_1 395493.BegalDRAFT_2711 2.01e-19 89.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,460RT@72273|Thiotrichales 72273|Thiotrichales S Permease YjgP YjgQ - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_11464_2 500637.PROVRUST_06414 1.28e-27 113.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,3Z77J@586|Providencia 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score 10.00 lptG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iSSON_1240.SSON_4447 YjgP_YjgQ k141_21258_1 1184267.A11Q_2051 1.99e-68 226.0 COG1352@1|root,COG1352@2|Bacteria,1QY2J@1224|Proteobacteria,43AK1@68525|delta/epsilon subdivisions,2MTJG@213481|Bdellovibrionales,2X60B@28221|Deltaproteobacteria 213481|Bdellovibrionales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - - - - - - - - - - - k141_17750_1 1348114.OM33_14290 1.58e-52 183.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,2PZNZ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_17750_2 1122201.AUAZ01000005_gene626 7.91e-146 431.0 COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,464X2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_19157_1 398580.Dshi_2556 1.69e-47 168.0 COG3500@1|root,COG3500@2|Bacteria,1Q2U5@1224|Proteobacteria,2U4UE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Late control gene D protein - - - - - - - - - - - - - k141_10787_1 571166.KI421508_gene62 2.24e-05 46.2 COG4367@1|root,COG4367@2|Bacteria,1MU6T@1224|Proteobacteria,2TR0D@28211|Alphaproteobacteria 28211|Alphaproteobacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - - k141_10787_2 1449351.RISW2_01975 4.42e-123 365.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2TTTG@28211|Alphaproteobacteria,4KKQP@93682|Roseivivax 28211|Alphaproteobacteria U Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_17010_1 177437.HRM2_39210 3.1e-78 240.0 COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,42PWK@68525|delta/epsilon subdivisions,2WKW1@28221|Deltaproteobacteria,2MI9E@213118|Desulfobacterales 28221|Deltaproteobacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_17010_2 879212.DespoDRAFT_00489 4.11e-46 161.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WJTJ@28221|Deltaproteobacteria,2MIYA@213118|Desulfobacterales 28221|Deltaproteobacteria M MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_2374_1 1131451.O1K_06532 2.36e-90 289.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales 135614|Xanthomonadales C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k141_302_2 396588.Tgr7_1249 1.21e-13 73.2 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales 135613|Chromatiales NU FimV C-terminal - - - ko:K08086 - - - - ko00000 - - - TPR_19 k141_3122_1 2340.JV46_03550 7.34e-89 280.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Transket_pyr,Transketolase_C,Transketolase_N k141_5882_1 713586.KB900536_gene122 4.9e-06 48.1 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales 135613|Chromatiales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_5882_2 754477.Q7C_293 3.85e-70 221.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,4605V@72273|Thiotrichales 72273|Thiotrichales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_18419_1 1288826.MSNKSG1_12692 2.19e-235 651.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein k141_18419_2 1288826.MSNKSG1_12687 1.07e-102 297.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,466EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k141_18419_3 1288826.MSNKSG1_12682 0.0 1583.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,46404@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_18419_4 1288826.MSNKSG1_12677 2.33e-205 569.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,464HG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 AA_kinase,NAT k141_18419_5 1288826.MSNKSG1_12672 6.81e-274 752.0 28ZNG@1|root,2ZMDP@2|Bacteria,1P4VR@1224|Proteobacteria,1SUA8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18419_6 1288826.MSNKSG1_12667 1.14e-237 655.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k141_12861_1 999541.bgla_2g03980 3.34e-30 125.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,1K160@119060|Burkholderiaceae 28216|Betaproteobacteria M Rhs element Vgr - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Gp5_C,Phage_GPD k141_11465_1 713586.KB900536_gene2731 3.39e-104 302.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1WX8R@135613|Chromatiales 135613|Chromatiales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_19158_1 1137271.AZUM01000004_gene4179 1.09e-14 76.3 COG0204@1|root,COG0204@2|Bacteria,2GJBQ@201174|Actinobacteria,4E42V@85010|Pseudonocardiales 201174|Actinobacteria I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_16296_1 105559.Nwat_0345 2.08e-119 352.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV pilus assembly protein PilM - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_16296_2 105559.Nwat_0346 2.19e-13 68.9 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales 135613|Chromatiales NU PFAM Fimbrial assembly - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_17751_1 1296416.JACB01000043_gene1860 1.25e-35 129.0 COG3279@1|root,COG3279@2|Bacteria,4NKFH@976|Bacteroidetes,1I20B@117743|Flavobacteriia 976|Bacteroidetes KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR k141_17751_2 313603.FB2170_05110 2.16e-32 125.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PG13@252356|Maribacter 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 k141_21259_2 561230.PC1_1622 3.97e-33 118.0 2C20N@1|root,31HY7@2|Bacteria,1QFMQ@1224|Proteobacteria,1TCX4@1236|Gammaproteobacteria,1MTR7@122277|Pectobacterium 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21925_1 748247.AZKH_3183 3.2e-68 219.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJ59@28216|Betaproteobacteria,2KVX5@206389|Rhodocyclales 206389|Rhodocyclales E Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_21925_2 85643.Tmz1t_1329 2.98e-79 256.0 COG2199@1|root,COG2972@1|root,COG2199@2|Bacteria,COG2972@2|Bacteria,1RGCV@1224|Proteobacteria,2VKYZ@28216|Betaproteobacteria,2KXWN@206389|Rhodocyclales 206389|Rhodocyclales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_3123_1 1283300.ATXB01000002_gene2877 1.05e-92 283.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1XE9R@135618|Methylococcales 135618|Methylococcales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_4508_1 631454.N177_3572 1.8e-05 46.6 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,1JN4G@119043|Rhodobiaceae 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_4508_2 367336.OM2255_04495 1.57e-34 121.0 COG2919@1|root,COG2919@2|Bacteria,1NGSW@1224|Proteobacteria,2UJYE@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Septum formation initiator - - - - - - - - - - - - DivIC k141_20571_3 396588.Tgr7_0300 2.59e-101 314.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_1721_1 1288826.MSNKSG1_14337 1.78e-159 454.0 COG2421@1|root,COG2421@2|Bacteria,1MVRT@1224|Proteobacteria,1RQDU@1236|Gammaproteobacteria,4641U@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetamidase formamidase fmdA - 3.5.1.49 ko:K01455 ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200 - R00524 RC02432,RC02810 ko00000,ko00001,ko01000 - - - FmdA_AmdA k141_1721_2 1288826.MSNKSG1_14342 1.99e-158 450.0 COG0542@1|root,COG0542@2|Bacteria,1PWAB@1224|Proteobacteria,1RRT2@1236|Gammaproteobacteria,4656B@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0542 ATPases with chaperone activity, ATP-binding subunit - - - - - - - - - - - - AAA_2,ClpB_D2-small k141_17752_1 1382230.ASAP_2763 5.63e-20 88.2 2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12161_1 631362.Thi970DRAFT_04697 9.68e-218 639.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_12862_1 1288826.MSNKSG1_09458 4.06e-70 221.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RW1Q@1236|Gammaproteobacteria,4663X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases atuD - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_19799_1 713586.KB900536_gene2819 1.13e-176 506.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales 135613|Chromatiales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_11466_1 1454004.AW11_00442 7.99e-35 134.0 COG1819@1|root,COG1819@2|Bacteria,1REWD@1224|Proteobacteria,2VR80@28216|Betaproteobacteria 28216|Betaproteobacteria CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - - - - - - - - - - Glyco_tran_28_C k141_15639_1 1288826.MSNKSG1_09423 0.0 1099.0 COG1593@1|root,COG1593@2|Bacteria,1PJM6@1224|Proteobacteria,1RPHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_16433_2 1288826.MSNKSG1_10223 1.97e-85 253.0 COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,1S49H@1236|Gammaproteobacteria,4680G@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein hpaR - - - - - - - - - - - MarR k141_448_1 228410.NE2298 1.13e-21 92.4 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,372D9@32003|Nitrosomonadales 28216|Betaproteobacteria I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_448_2 1240350.AMZE01000120_gene3464 3.02e-25 100.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1YVAA@136845|Pseudomonas putida group 1236|Gammaproteobacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_19300_1 1288826.MSNKSG1_01708 2.01e-134 380.0 COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,1RPRR@1236|Gammaproteobacteria,46834@72275|Alteromonadaceae 1236|Gammaproteobacteria S intracellular protease pfpI - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_19300_2 1288826.MSNKSG1_01713 3.28e-154 433.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1SB6A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SOS response associated peptidase (SRAP) - - - - - - - - - - - - SRAP k141_19300_3 1288826.MSNKSG1_01718 2.04e-123 360.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,469KP@72275|Alteromonadaceae 1236|Gammaproteobacteria I alpha/beta hydrolase fold - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 k141_10922_1 443152.MDG893_07285 2.25e-91 286.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4650M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 k141_17136_1 314292.VAS14_21462 2.81e-54 193.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XT0R@135623|Vibrionales 135623|Vibrionales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C k141_18531_1 1323663.AROI01000014_gene87 2.01e-59 192.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Transport Permease Protein yadH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_18531_2 713587.THITH_09030 3.8e-74 232.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1WWXT@135613|Chromatiales 135613|Chromatiales V PFAM ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_21380_1 396588.Tgr7_1464 4.96e-19 85.5 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales 135613|Chromatiales S Belongs to the GcvT family - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_2508_1 713586.KB900536_gene1705 6.52e-23 95.9 COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria,1X286@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind k141_2508_2 472759.Nhal_0208 9.18e-59 195.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1WVVC@135613|Chromatiales 135613|Chromatiales F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_4640_1 644801.Psest_4096 3.83e-14 73.9 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1YZZK@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG0826 Collagenase and related proteases yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_4640_2 670487.Ocepr_0084 3.57e-126 380.0 COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus 2|Bacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_12321_1 395493.BegalDRAFT_0335 1.01e-119 358.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,45ZTQ@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_8,RnfC_N,SLBB k141_10174_1 1288826.MSNKSG1_11493 1.7e-119 348.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,466XK@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase FAD binding subunit glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_10174_2 1288826.MSNKSG1_11488 1.9e-268 735.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_1158_1 644107.SL1157_0912 1.64e-119 358.0 COG3962@1|root,COG3962@2|Bacteria,1MW0P@1224|Proteobacteria,2TR12@28211|Alphaproteobacteria,4NA2C@97050|Ruegeria 28211|Alphaproteobacteria E Belongs to the TPP enzyme family iolD - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_13699_1 744979.R2A130_0957 1.34e-52 175.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2TRV8@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type proline glycine betaine transport systems periplasmic components proX - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_13699_2 1380367.JIBC01000006_gene222 3.15e-33 119.0 COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,2U5RY@28211|Alphaproteobacteria,3ZWNX@60136|Sulfitobacter 28211|Alphaproteobacteria K Repressor involved in choline regulation of the bet genes betI - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N k141_19301_1 69328.PVLB_14435 3.42e-40 148.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_15807_1 1089439.KB902251_gene1565 1.88e-07 53.9 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales 72273|Thiotrichales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_13013_1 1123279.ATUS01000001_gene1468 9.53e-118 350.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1J5DG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_13013_2 715451.ambt_13205 2.12e-63 204.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,465DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_15051_2 311403.Arad_2811 1.3e-07 58.5 COG0438@1|root,COG2520@1|root,COG0438@2|Bacteria,COG2520@2|Bacteria,1RI6Q@1224|Proteobacteria,2UH7F@28211|Alphaproteobacteria,4BKIV@82115|Rhizobiaceae 28211|Alphaproteobacteria M Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k141_19923_1 1298593.TOL_1879 2.72e-30 112.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1XK2S@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein exbD1 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_19923_2 1198232.CYCME_1737 3.02e-20 86.3 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,460KS@72273|Thiotrichales 72273|Thiotrichales U MotA TolQ ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_5985_1 1535422.ND16A_0732 2.36e-74 235.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_10175_1 1269813.ATUL01000003_gene2478 2.9e-81 246.0 COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,1RXZV@1236|Gammaproteobacteria,1WWCC@135613|Chromatiales 135613|Chromatiales CQ BMC - - - - - - - - - - - - BMC k141_17137_1 1124780.ANNU01000076_gene811 1.09e-82 274.0 COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,47MJ2@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_18533_1 1002340.AFCF01000052_gene1538 2.71e-81 248.0 COG1802@1|root,COG1802@2|Bacteria,1P945@1224|Proteobacteria,2TV2V@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_10924_1 1353537.TP2_03040 3.08e-38 137.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,2XKV6@285107|Thioclava 28211|Alphaproteobacteria I Malonyl CoA-acyl carrier protein transacylase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_10924_2 1123360.thalar_01515 2.81e-53 174.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_22043_1 1298593.TOL_0751 1.41e-22 103.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RZ9E@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - HAMP,MCPsignal k141_3888_2 472759.Nhal_3582 2.51e-83 255.0 COG0569@1|root,COG0569@2|Bacteria,1RIP2@1224|Proteobacteria,1SKEI@1236|Gammaproteobacteria,1X03Z@135613|Chromatiales 135613|Chromatiales P TrkA-C domain - - - - - - - - - - - - TrkA_C k141_2509_1 1232683.ADIMK_3829 1.4e-64 207.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,46A7B@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class I and II yfdZ GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K14261 - - - - ko00000,ko01000,ko01007 - - iEcSMS35_1347.EcSMS35_2531,iSBO_1134.SBO_2405 Aminotran_1_2 k141_19302_1 748247.AZKH_2842 1.07e-27 112.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales 206389|Rhodocyclales T Sigma E regulatory protein, MucB RseB rseB - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_21381_1 396588.Tgr7_0560 5.45e-128 381.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_3261_1 1232683.ADIMK_3858 1.06e-113 339.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,1RQ5C@1236|Gammaproteobacteria,465H7@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 k141_3261_2 390235.PputW619_3605 3.99e-113 349.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Xanthine dehydrogenase xdhB - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_12323_1 1123368.AUIS01000001_gene2024 1.68e-94 296.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2NC0C@225057|Acidithiobacillales 225057|Acidithiobacillales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_8761_1 1288826.MSNKSG1_16331 4.05e-256 702.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_8761_2 1288826.MSNKSG1_16336 2.06e-208 581.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1RZ44@1236|Gammaproteobacteria 1236|Gammaproteobacteria N OmpA MotB - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_8761_3 1288826.MSNKSG1_16341 1.09e-166 466.0 COG1511@1|root,COG1511@2|Bacteria,1NYJB@1224|Proteobacteria,1S1D4@1236|Gammaproteobacteria 1236|Gammaproteobacteria U MotA TolQ ExbB proton channel family - - - - - - - - - - - - MotA_ExbB k141_8761_4 1415754.JQMK01000002_gene2140 1.17e-85 254.0 COG0824@1|root,COG0824@2|Bacteria,1RH20@1224|Proteobacteria,1S6RE@1236|Gammaproteobacteria,467YN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_8761_5 1288826.MSNKSG1_16351 1.51e-161 452.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,469ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S ThiJ/PfpI family-like - - - - - - - - - - - - DJ-1_PfpI k141_8761_6 1288826.MSNKSG1_16356 5.09e-160 450.0 COG0834@1|root,COG0834@2|Bacteria,1N4DM@1224|Proteobacteria,1SYZY@1236|Gammaproteobacteria,468U7@72275|Alteromonadaceae 1236|Gammaproteobacteria ET extracellular solute-binding protein, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_8761_7 1288826.MSNKSG1_16361 4.66e-98 285.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,468JY@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Thioesterase superfamily menI GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT k141_8761_8 1288826.MSNKSG1_16366 1.64e-206 575.0 COG2199@1|root,COG3706@2|Bacteria,1R48Q@1224|Proteobacteria,1RVD2@1236|Gammaproteobacteria,46CHH@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_8761_9 1288826.MSNKSG1_16371 5.4e-147 417.0 COG0730@1|root,COG0730@2|Bacteria,1RGCZ@1224|Proteobacteria,1S7QU@1236|Gammaproteobacteria,467QC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_8761_10 1288826.MSNKSG1_16376 4.54e-79 234.0 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0225 family ychJ - - ko:K09858 - - - - ko00000 - - - SEC-C k141_8761_11 1288826.MSNKSG1_16381 1.58e-82 244.0 COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,1SYE5@1236|Gammaproteobacteria,468DY@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_8761_12 1288826.MSNKSG1_16386 3.25e-195 543.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,465R2@72275|Alteromonadaceae 1236|Gammaproteobacteria S RarD protein rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_8761_13 1288826.MSNKSG1_16391 7.73e-53 165.0 COG1670@1|root,COG1670@2|Bacteria,1N9F9@1224|Proteobacteria,1SCFK@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Protein of unknown function (DUF3565) - - - - - - - - - - - - DUF3565 k141_8761_14 1288826.MSNKSG1_16396 2.04e-82 243.0 COG3011@1|root,COG3011@2|Bacteria,1PBWU@1224|Proteobacteria,1RTI1@1236|Gammaproteobacteria,4698P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_8761_15 1288826.MSNKSG1_16401 1.87e-279 769.0 COG2062@1|root,COG5607@1|root,COG2062@2|Bacteria,COG5607@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,4691U@72275|Alteromonadaceae 1236|Gammaproteobacteria T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - CHAD,His_Phos_1 k141_8761_16 1288826.MSNKSG1_16406 1.03e-205 585.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_7400_1 760117.JN27_11010 4.28e-19 85.9 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,474AH@75682|Oxalobacteraceae 28216|Betaproteobacteria S PFAM Phosphoribosyltransferase comF - - - - - - - - - - - Pribosyltran k141_3277_1 330214.NIDE2825 6.47e-97 307.0 COG2804@1|root,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae 2|Bacteria NU Type II/IV secretion system protein gspE - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_10935_1 1122194.AUHU01000002_gene2545 1.12e-72 229.0 COG0421@1|root,COG0421@2|Bacteria,1QWZZ@1224|Proteobacteria,1T31M@1236|Gammaproteobacteria,467WD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Methyltransf_25 k141_13047_1 1278309.KB907100_gene2217 2.44e-131 386.0 COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,1RPTW@1236|Gammaproteobacteria,1XH55@135619|Oceanospirillales 135619|Oceanospirillales S FAD-dependent dehydrogenases - - - ko:K07137 - - - - ko00000 - - - - k141_20683_1 1278309.KB907107_gene1736 5.66e-81 254.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XIEK@135619|Oceanospirillales 135619|Oceanospirillales K Flagellar regulatory protein FleQ - - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_19317_1 748247.AZKH_2618 6.61e-47 166.0 COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,2VITZ@28216|Betaproteobacteria,2KVSF@206389|Rhodocyclales 206389|Rhodocyclales S Peptidase C13 family - - - - - - - - - - - - Peptidase_C13 k141_9437_1 83406.HDN1F_13800 1.25e-31 128.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1J593@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit IV02_00930 - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_15064_1 1278309.KB907099_gene2687 2.81e-217 605.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP3X@1236|Gammaproteobacteria,1XIGM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21826 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k141_15064_2 1278309.KB907099_gene2678 1.61e-238 662.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XHQK@135619|Oceanospirillales 135619|Oceanospirillales E Serine dehydratase beta chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_7433_1 1201293.AKXQ01000019_gene1174 8.63e-11 58.9 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_17166_1 595494.Tola_1243 2.22e-71 235.0 28IZT@1|root,2Z8X3@2|Bacteria,1R4RF@1224|Proteobacteria,1SK6Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18564_1 1380358.JADJ01000012_gene792 1.69e-100 305.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RVXM@1236|Gammaproteobacteria,1XI3N@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_6674_1 1287276.X752_22470 3.3e-10 67.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Adenylate Guanylate cyclase cyaD1 - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_6674_2 1122599.AUGR01000002_gene3556 7.29e-33 126.0 2CPPK@1|root,32SJJ@2|Bacteria,1MZQ2@1224|Proteobacteria,1SABH@1236|Gammaproteobacteria,1XQA8@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 k141_8187_1 1137799.GZ78_08295 3.84e-64 202.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XJ5P@135619|Oceanospirillales 135619|Oceanospirillales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k141_3278_1 314232.SKA53_02311 2.73e-89 280.0 COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,1MV6I@1224|Proteobacteria,2TTWN@28211|Alphaproteobacteria,2P9P4@245186|Loktanella 28211|Alphaproteobacteria G Uncharacterized protein conserved in bacteria (DUF2090) - - 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DUF2090,PfkB k141_10936_2 1523503.JPMY01000037_gene1748 2.64e-31 122.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_17905_1 105559.Nwat_2285 2.46e-37 142.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_17905_2 187272.Mlg_0035 3.66e-21 85.1 COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1WZ84@135613|Chromatiales 135613|Chromatiales H TIGRFAM thiamine biosynthesis protein ThiS - - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_17905_4 595494.Tola_0959 4.84e-11 62.4 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1Y3H9@135624|Aeromonadales 135624|Aeromonadales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_12342_1 1278309.KB907100_gene1823 3.86e-96 285.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1XIAD@135619|Oceanospirillales 135619|Oceanospirillales E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_12342_2 1278309.KB907100_gene1824 1.15e-268 758.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XHBY@135619|Oceanospirillales 135619|Oceanospirillales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_14347_1 1278309.KB907104_gene837 1.37e-82 251.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1S4U5@1236|Gammaproteobacteria,1XJZ6@135619|Oceanospirillales 135619|Oceanospirillales T serine threonine protein phosphatase - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_14347_2 1278309.KB907104_gene836 1.23e-74 228.0 COG3913@1|root,COG3913@2|Bacteria,1QFVW@1224|Proteobacteria,1RSPG@1236|Gammaproteobacteria 1236|Gammaproteobacteria T type VI secretion-associated protein, BMA_A0400 family - - - ko:K11890 ko02025,map02025 - - - ko00000,ko00001,ko02044 - - - DUF2094 k141_4667_1 1288826.MSNKSG1_10238 0.0 993.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,468GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_17167_1 314285.KT71_11695 4.56e-23 96.3 COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,1S2PS@1236|Gammaproteobacteria 1236|Gammaproteobacteria O methyltransferase activity - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT k141_7434_2 1121935.AQXX01000045_gene4599 2.77e-18 80.1 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1XK6G@135619|Oceanospirillales 135619|Oceanospirillales O Redoxin - - - - - - - - - - - - AhpC-TSA k141_5991_1 1278309.KB907100_gene1950 8.98e-125 363.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1XH9Y@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_6130_1 519989.ECTPHS_12828 1.5e-63 195.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1X16T@135613|Chromatiales 135613|Chromatiales C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K04755 - - - - ko00000 - - - Fer2 k141_6130_2 998674.ATTE01000001_gene4333 5.43e-33 114.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Fe-S assembly protein IscX iscX GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - - - - - - - - - - Fe-S_assembly k141_4803_1 1288826.MSNKSG1_13732 7.79e-20 87.4 COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,1T1TS@1236|Gammaproteobacteria,468B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_4803_2 1288826.MSNKSG1_13737 2.86e-213 589.0 COG0583@1|root,COG0583@2|Bacteria,1MV36@1224|Proteobacteria,1S8X9@1236|Gammaproteobacteria,46B5P@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_5497_2 1117319.PSPO_03160 1.77e-32 124.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,2PZUM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440 Ala_racemase_C,Ala_racemase_N k141_19424_1 279714.FuraDRAFT_1436 6.61e-78 241.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,2KQ6D@206351|Neisseriales 206351|Neisseriales P Binding-protein-dependent transport system inner membrane component pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_19424_2 314278.NB231_00770 1.92e-132 384.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales 135613|Chromatiales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_13864_1 1278309.KB907110_gene3183 1.68e-118 349.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XHUY@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_13864_2 1278309.KB907110_gene3182 0.0 969.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XH25@135619|Oceanospirillales 135619|Oceanospirillales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_13864_3 1278309.KB907110_gene3181 4.78e-48 154.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XKMB@135619|Oceanospirillales 135619|Oceanospirillales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_13864_4 1278309.KB907110_gene3180 1.6e-192 539.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1XIV0@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_2663_1 653733.Selin_0377 1.5e-09 63.9 COG3221@1|root,COG3221@2|Bacteria 2|Bacteria P organic phosphonate transport phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_8888_1 626887.J057_17920 1.19e-21 97.4 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar Motor Protein motB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_13188_1 1288826.MSNKSG1_15112 1.19e-235 664.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,464R6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_11110_1 1265503.KB905168_gene1438 1.28e-37 141.0 COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RYEB@1236|Gammaproteobacteria,2Q750@267889|Colwelliaceae 1236|Gammaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_12527_1 717774.Marme_3223 6.91e-85 259.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XHDM@135619|Oceanospirillales 135619|Oceanospirillales N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_12527_2 349124.Hhal_0485 9.01e-20 87.0 COG3190@1|root,COG3190@2|Bacteria,1PQ37@1224|Proteobacteria,1TK5Y@1236|Gammaproteobacteria,1WZNW@135613|Chromatiales 135613|Chromatiales N PFAM flagellar biosynthesis protein, FliO - - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_16626_1 404589.Anae109_0587 4.86e-35 131.0 COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,42VE6@68525|delta/epsilon subdivisions 1224|Proteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_13214_1 1049564.TevJSym_ak00870 4.54e-46 160.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1J4U9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P antiporter yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_20784_2 520999.PROVALCAL_03402 1.45e-26 100.0 2E38J@1|root,32Y88@2|Bacteria,1NDNB@1224|Proteobacteria,1SDFI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VRR_NUC - - - - - - - - - - - - VRR_NUC k141_20784_3 743720.Psefu_1426 7.08e-19 85.1 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k141_18112_2 1469613.JT55_01940 2.56e-35 127.0 COG2197@1|root,COG2197@2|Bacteria,1RDUR@1224|Proteobacteria,2U7E1@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT COG2771 DNA-binding HTH domain-containing proteins - - - - - - - - - - - - GerE k141_613_2 863365.XHC_0810 7.08e-19 88.6 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1X30V@135614|Xanthomonadales 135614|Xanthomonadales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_15977_1 631362.Thi970DRAFT_02092 1.02e-183 532.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXQ0@135613|Chromatiales 135613|Chromatiales P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C k141_11111_1 1120999.JONM01000004_gene3663 3.12e-54 183.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,2KRFG@206351|Neisseriales 206351|Neisseriales T Histidine kinase - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_6155_1 511.JT27_08705 2.43e-45 153.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,3T3RD@506|Alcaligenaceae 28216|Betaproteobacteria S Phospholipase/Carboxylesterase estB - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_6155_2 291112.PAU_04123 1.72e-25 99.0 COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the frataxin family cyaY GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 - ko:K06202 - - - - ko00000 - - iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108 Frataxin_Cyay k141_15172_1 1288826.MSNKSG1_06658 7.68e-260 721.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,4658U@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3267 Type II secretory pathway, component ExeA gspA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 k141_15172_2 1288826.MSNKSG1_06663 0.0 988.0 COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,1RSDG@1236|Gammaproteobacteria,463Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - DUF3336,Patatin k141_15172_3 1288826.MSNKSG1_06668 2.21e-179 500.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,466E2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Surface lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_15172_4 1288826.MSNKSG1_06673 1.08e-91 268.0 COG0824@1|root,COG0824@2|Bacteria,1MZTU@1224|Proteobacteria,1S7VY@1236|Gammaproteobacteria,468KX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase fcbC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_15172_5 1288826.MSNKSG1_06678 3.17e-259 711.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,464PA@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0332 3-oxoacyl- acyl-carrier-protein synthase III fabH - 2.3.1.207 ko:K16872 - - - - ko00000,ko01000 - - - ACP_syn_III,ACP_syn_III_C k141_15172_6 1288826.MSNKSG1_06683 0.0 2434.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,464K7@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_15172_7 1288826.MSNKSG1_06688 5.92e-186 528.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II fadD1 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - iJN746.PP_4550 AMP-binding,AMP-binding_C k141_1355_2 1163617.SCD_n02264 9.45e-137 411.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria 28216|Betaproteobacteria C nitrite reductase NAD(P)H nasD - 1.18.1.1,1.7.1.15 ko:K00362,ko:K05297 ko00071,ko00910,ko01120,map00071,map00910,map01120 M00530 R00787,R02000 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_19446_1 1137799.GZ78_19675 6.4e-27 103.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XK4R@135619|Oceanospirillales 135619|Oceanospirillales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_19446_2 998674.ATTE01000001_gene1514 6.52e-35 128.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,460FC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_18113_1 1238190.AMQY01000017_gene1426 3.22e-12 67.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XI1F@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_13889_2 519989.ECTPHS_01979 4.93e-71 238.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 k141_14481_1 1278309.KB907101_gene543 2.4e-202 569.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XH5E@135619|Oceanospirillales 135619|Oceanospirillales C 2-oxoglutarate dehydrogenase complex lpdG - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_14481_2 1278309.KB907101_gene542 3.22e-253 699.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1XHYG@135619|Oceanospirillales 135619|Oceanospirillales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_14481_3 1278309.KB907101_gene541 0.0 1818.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1XHDK@135619|Oceanospirillales 135619|Oceanospirillales C 2-oxoglutarate dehydrogenase sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_1991_1 1249627.D779_2768 4.78e-18 87.8 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales 135613|Chromatiales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_1991_2 287.DR97_4954 9.43e-59 188.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1YCZQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2062) TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_1991_3 187272.Mlg_1439 3.75e-39 137.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1WVXB@135613|Chromatiales 135613|Chromatiales V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_13215_2 472759.Nhal_1052 2.54e-14 71.2 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1WXZH@135613|Chromatiales 135613|Chromatiales G PFAM Phosphoglycerate mutase - - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_3433_2 318167.Sfri_1670 2.46e-31 121.0 2EFTY@1|root,339K2@2|Bacteria,1NIIB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_3433_4 1509405.GV67_22545 7.11e-18 84.0 COG4585@1|root,COG4585@2|Bacteria,1R0QR@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - - k141_8343_1 1278309.KB907099_gene2595 4.34e-31 112.0 COG3212@1|root,COG3212@2|Bacteria,1QAXF@1224|Proteobacteria,1T6D3@1236|Gammaproteobacteria,1XQIP@135619|Oceanospirillales 135619|Oceanospirillales S Peptidase propeptide and YPEB domain - - - - - - - - - - - - - k141_8343_2 1278309.KB907099_gene2594 4.21e-96 283.0 COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria,1XPRT@135619|Oceanospirillales 135619|Oceanospirillales C Dihaem cytochrome c - - - - - - - - - - - - DHC k141_8343_4 1278309.KB907099_gene2592 4.12e-93 277.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1XK5E@135619|Oceanospirillales 135619|Oceanospirillales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_20785_1 1337093.MBE-LCI_0213 1.42e-08 52.8 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,2P939@245186|Loktanella 28211|Alphaproteobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_20785_2 545276.KB898724_gene1881 1.1e-126 383.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales 135613|Chromatiales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_16628_1 396588.Tgr7_3022 2.68e-74 247.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_22225_1 1166018.FAES_0300 3.47e-64 217.0 COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,47JD8@768503|Cytophagia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k141_12530_1 342113.DM82_549 3.41e-29 115.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2VKUI@28216|Betaproteobacteria,1K1N1@119060|Burkholderiaceae 28216|Betaproteobacteria M glycosyl transferase family 2 lgtF - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 k141_8344_1 1219031.BBJR01000041_gene2908 1.81e-24 105.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria,4AAAR@80864|Comamonadaceae 28216|Betaproteobacteria T Diguanylate phosphodiesterase - - - - - - - - - - - - EAL,HDOD k141_18747_1 1318628.MARLIPOL_04150 9.02e-124 369.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM,DctQ k141_18747_2 626887.J057_05701 1.49e-38 135.0 COG4665@1|root,COG4665@2|Bacteria,1RE14@1224|Proteobacteria,1S582@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - - - - - - - - - - DctQ k141_17318_1 1288826.MSNKSG1_11428 0.0 1022.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_17318_2 1288826.MSNKSG1_11423 5.5e-292 810.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_17318_3 1288826.MSNKSG1_11403 3.39e-170 476.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,46600@72275|Alteromonadaceae 1236|Gammaproteobacteria S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH k141_19447_1 582744.Msip34_1421 2.95e-30 121.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,2KM1H@206350|Nitrosomonadales 206350|Nitrosomonadales H TIGRFAM squalene-associated FAD-dependent desaturase - - - - - - - - - - - - Amino_oxidase k141_19447_2 626887.J057_19080 1.75e-31 116.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,46407@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yciK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short k141_3434_1 511.JT27_15085 4.55e-38 134.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,3T488@506|Alcaligenaceae 28216|Betaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_13891_1 357808.RoseRS_1127 4.83e-50 174.0 COG0318@1|root,COG0318@2|Bacteria,2G7N1@200795|Chloroflexi,37718@32061|Chloroflexia 32061|Chloroflexia IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_1356_1 1278309.KB907101_gene659 3.66e-145 434.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XHZN@135619|Oceanospirillales 135619|Oceanospirillales S DNA internalization-related competence protein ComEC Rec2 rec2 - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_12531_1 754476.Q7A_1959 1.11e-18 80.9 2FE8Y@1|root,3468T@2|Bacteria,1P2WQ@1224|Proteobacteria,1SR4V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15978_1 472759.Nhal_2225 4.91e-79 248.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1X07Y@135613|Chromatiales 135613|Chromatiales E TIGRFAM amidase, hydantoinase carbamoylase - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_15978_2 323261.Noc_0780 5.69e-113 331.0 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria,1WXHF@135613|Chromatiales 135613|Chromatiales Q PFAM isochorismatase hydrolase - - - - - - - - - - - - Isochorismatase k141_15978_3 472759.Nhal_2223 4.9e-53 179.0 COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,1RR54@1236|Gammaproteobacteria,1X0GD@135613|Chromatiales 135613|Chromatiales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_18748_1 1245471.PCA10_46080 1.02e-07 58.9 COG1361@1|root,COG2202@1|root,COG2931@1|root,COG3188@1|root,COG3210@1|root,COG1361@2|Bacteria,COG2202@2|Bacteria,COG2931@2|Bacteria,COG3188@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1RX6F@1236|Gammaproteobacteria,1YJEZ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria MNQU Domain of unknown function (DUF4347) - - - - - - - - - - - - DUF4347 k141_6156_1 1278309.KB907109_gene3249 1.29e-176 494.0 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,1XIXT@135619|Oceanospirillales 135619|Oceanospirillales H COG0720 6-pyruvoyl-tetrahydropterin synthase - - - - - - - - - - - - PTPS k141_6156_2 1278309.KB907109_gene3248 2.21e-137 391.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XJD1@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the pseudouridine synthase RsuA family rsuA - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_17319_1 1121271.AUCM01000003_gene1878 5.14e-28 112.0 COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Domain of unknown function (DUF4167) - - - - - - - - - - - - DUF4167 k141_15174_1 998674.ATTE01000001_gene4005 9.94e-87 266.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,461UD@72273|Thiotrichales 72273|Thiotrichales V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_3 k141_14483_1 644107.SL1157_0273 3.35e-105 315.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,4N9SX@97050|Ruegeria 28211|Alphaproteobacteria T PhoH-like protein phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_20787_1 1382230.ASAP_2763 1.77e-07 56.6 2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_8346_1 318161.Sden_3301 2.78e-97 294.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,2QAPX@267890|Shewanellaceae 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB1 - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_19448_1 1288826.MSNKSG1_10343 2.53e-135 394.0 COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,1RPW8@1236|Gammaproteobacteria,465IF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q cytochrome P450 - - - - - - - - - - - - p450 k141_6157_1 1278309.KB907107_gene1641 1.76e-88 273.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria,1XRHB@135619|Oceanospirillales 135619|Oceanospirillales T Forkhead associated domain - - - ko:K11894 - - - - ko00000,ko02044 3.A.23.1 - - FHA k141_9612_1 85643.Tmz1t_3487 1.33e-56 185.0 COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2VN1E@28216|Betaproteobacteria,2KUEP@206389|Rhodocyclales 206389|Rhodocyclales K transcriptional - - - - - - - - - - - - FCD,GntR k141_9612_2 1238182.C882_4548 2.98e-225 637.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JQI2@204441|Rhodospirillales 204441|Rhodospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_1457_2 1278309.KB907106_gene1365 8.24e-36 129.0 COG4726@1|root,COG4726@2|Bacteria 2|Bacteria NU Pilus assembly protein PilX pilX - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX,PilX_N k141_14717_1 323848.Nmul_A0521 5.35e-22 100.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,371ZN@32003|Nitrosomonadales 28216|Betaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C k141_9811_1 1535287.JP74_09725 2.04e-43 152.0 COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,2TSDV@28211|Alphaproteobacteria,3N7RD@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria G pfkB family carbohydrate kinase kdgK GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008673,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB k141_9811_2 311402.Avi_3898 1.65e-28 113.0 COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,4B8K8@82115|Rhizobiaceae 28211|Alphaproteobacteria G dehydratase - - 4.2.1.42,4.2.1.7 ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00631 R01540,R05608 RC00543 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C,SAF k141_11925_2 1123367.C666_08430 1.69e-68 219.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales 206389|Rhodocyclales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate - 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_55_1 396588.Tgr7_0808 1.92e-91 279.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_14009_1 398767.Glov_1799 2.87e-63 209.0 28IZT@1|root,2Z8X3@2|Bacteria,1R4RF@1224|Proteobacteria,42QV2@68525|delta/epsilon subdivisions,2WMYU@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_16090_1 765913.ThidrDRAFT_2417 3.65e-39 141.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1WWKN@135613|Chromatiales 135613|Chromatiales C C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - k141_12623_1 1122604.JONR01000011_gene3726 9.11e-06 51.2 COG0204@1|root,COG0204@2|Bacteria,1PCK0@1224|Proteobacteria,1SXN6@1236|Gammaproteobacteria,1X6FD@135614|Xanthomonadales 135614|Xanthomonadales I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_12623_2 1123518.ARWI01000001_gene902 3.84e-63 202.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,4605Y@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_20296_1 1415780.JPOG01000001_gene2740 2.28e-255 728.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1XCEY@135614|Xanthomonadales 135614|Xanthomonadales C Molydopterin dinucleotide binding domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_4231_1 1002340.AFCF01000077_gene3046 1.43e-75 231.0 COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2U632@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q 2-hydroxychromene-2-carboxylate isomerase - - - - - - - - - - - - DSBA k141_1458_1 195250.CM001776_gene381 8.99e-19 92.8 COG2203@1|root,COG3852@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG5002@2|Bacteria,1G3VN@1117|Cyanobacteria,1H0NV@1129|Synechococcus 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_3 k141_5659_3 1042375.AFPL01000022_gene2709 4.11e-157 457.0 28P7P@1|root,2ZC1Y@2|Bacteria,1RBDI@1224|Proteobacteria,1S2AW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S outer membrane porin, OprD family - - - - - - - - - - - - OprD k141_5659_5 1278309.KB907099_gene2656 3.46e-207 589.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,1XH3C@135619|Oceanospirillales 135619|Oceanospirillales KQ transcriptional regulator - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_11258_1 443152.MDG893_09386 1.34e-181 515.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,464ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - iPC815.YPO3376 Enolase_C,Enolase_N k141_11258_2 443152.MDG893_07410 1.26e-120 355.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,466SF@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0524 Sugar kinases, ribokinase family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_9812_1 1121904.ARBP01000013_gene356 2.93e-83 258.0 COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,47P9V@768503|Cytophagia 976|Bacteroidetes M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_3 k141_3546_3 1049564.TevJSym_ad00130 2.24e-07 48.9 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,1J66K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_10526_1 1234364.AMSF01000088_gene2726 2.52e-38 132.0 COG3832@1|root,COG3832@2|Bacteria,1REDB@1224|Proteobacteria,1S3Z4@1236|Gammaproteobacteria,1XDA6@135614|Xanthomonadales 135614|Xanthomonadales S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 k141_7038_2 1227349.C170_23385 2.15e-20 95.5 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,26SUS@186822|Paenibacillaceae 91061|Bacilli T serine threonine protein phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_19581_1 225937.HP15_2530 4.16e-34 139.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases bprV - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,Peptidase_S8 k141_4232_1 754476.Q7A_2986 1.72e-35 132.0 COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales 72273|Thiotrichales G PFAM pfkB family carbohydrate kinase - - 2.7.1.3 ko:K00846 ko00051,ko01100,ko01120,map00051,map01100,map01120 - R00866,R03819 RC00002,RC00017,RC00608 ko00000,ko00001,ko01000,ko04147 - - - PfkB,Rieske k141_21019_1 1278309.KB907110_gene3203 4.27e-143 405.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1XH4W@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_21019_2 1278309.KB907110_gene3202 2.4e-207 578.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XH4R@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_21019_3 1278309.KB907110_gene3201 2.86e-24 97.4 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1XHFA@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_7749_1 1278309.KB907102_gene278 4.75e-32 122.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Big_5,Calx-beta,DUF4347,FG-GAP,Laminin_G_3,Peptidase_S8,VCBS,VWA_2,W_rich_C k141_7749_2 1278309.KB907102_gene277 5.66e-137 393.0 28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,1RP8T@1236|Gammaproteobacteria,1XIH6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7749_3 472759.Nhal_0638 1.2e-21 89.4 COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1SCPK@1236|Gammaproteobacteria,1X264@135613|Chromatiales 135613|Chromatiales S Membrane - - - - - - - - - - - - - k141_14719_1 557598.LHK_01545 3.82e-32 120.0 2DZ82@1|root,32V6V@2|Bacteria,1N3UK@1224|Proteobacteria,2VY68@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_14719_2 1003200.AXXA_27970 5.53e-08 53.5 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2VSX1@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_13323_1 519989.ECTPHS_05350 3.9e-30 112.0 COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales 135613|Chromatiales L PFAM HhH-GPD - - - ko:K07457 - - - - ko00000 - - - HhH-GPD k141_13323_2 1169143.KB911044_gene3404 7.57e-15 75.9 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,1K0N5@119060|Burkholderiaceae 28216|Betaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_18885_2 1121374.KB891586_gene2727 8.09e-48 164.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_20297_1 1472716.KBK24_0110205 5.1e-29 108.0 COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,2VVRD@28216|Betaproteobacteria,1K8AU@119060|Burkholderiaceae 28216|Betaproteobacteria S addiction module killer protein - - - - - - - - - - - - Gp49 k141_20297_2 1094496.m07a_pML00700 3.14e-09 57.0 COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,2UGDM@28211|Alphaproteobacteria,48U8F@772|Bartonellaceae 28211|Alphaproteobacteria K addiction module antidote protein - - - - - - - - - - - - HTH_3 k141_16091_1 522306.CAP2UW1_3446 2.77e-09 63.9 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KQRC@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria NT chemotaxis sensory transducer - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,NIT k141_2147_1 1123228.AUIH01000114_gene3699 1.21e-81 251.0 COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,1S2MT@1236|Gammaproteobacteria,1XPYX@135619|Oceanospirillales 135619|Oceanospirillales P ChaC-like protein - - - - - - - - - - - - ChaC k141_21661_1 545264.KB898747_gene486 5.95e-14 72.8 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1WXSF@135613|Chromatiales 135613|Chromatiales S Belongs to the BI1 family - - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_21661_2 1004785.AMBLS11_09710 0.000808 41.2 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,4662X@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain uvrY GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_14735_1 95619.PM1_0209115 1.39e-151 446.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleQ - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_1466_3 1307437.J139_07662 6.55e-35 121.0 2E53A@1|root,32ZWE@2|Bacteria,1N77T@1224|Proteobacteria,1SA8T@1236|Gammaproteobacteria,2Q354@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S YrhK-like protein - - - - - - - - - - - - YrhK k141_3565_1 1123247.AUIJ01000001_gene1731 4.53e-69 220.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_2858_1 1288826.MSNKSG1_01888 2.99e-177 499.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,464IS@72275|Alteromonadaceae 1236|Gammaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_2858_2 1288826.MSNKSG1_01893 9.37e-276 754.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RQ9K@1236|Gammaproteobacteria,465Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria C alcohol dehydrogenase - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_2858_3 1288826.MSNKSG1_01898 1.24e-255 701.0 COG3938@1|root,COG3938@2|Bacteria,1N02K@1224|Proteobacteria,1RYRX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the proline racemase family - - - - - - - - - - - - Pro_racemase k141_2858_4 1288826.MSNKSG1_01903 1.84e-126 374.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RNHN@1236|Gammaproteobacteria,469NB@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acs-2 - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_4935_1 1288826.MSNKSG1_08458 7.42e-95 283.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_4935_2 1288826.MSNKSG1_08463 2.79e-170 476.0 COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,4678V@72275|Alteromonadaceae 1236|Gammaproteobacteria S glutamine amidotransferases - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_4935_3 1288826.MSNKSG1_08468 2.15e-142 404.0 COG2968@1|root,COG2968@2|Bacteria 2|Bacteria S cellular response to heat - - - ko:K09807 - - - - ko00000 - - - SIMPL k141_4935_4 1288826.MSNKSG1_08473 0.0 2281.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,4652R@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ytfN GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_4935_5 1288826.MSNKSG1_08478 0.0 1094.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,465KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0729 Outer membrane protein ytfM GO:0002790,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_4935_6 1288826.MSNKSG1_08483 8.45e-238 654.0 28MGC@1|root,2ZATM@2|Bacteria,1R9KE@1224|Proteobacteria,1RZP6@1236|Gammaproteobacteria,46655@72275|Alteromonadaceae 1236|Gammaproteobacteria S Preprotein translocase subunit SecA - - - - - - - - - - - - - k141_4935_7 1288826.MSNKSG1_08488 0.0 959.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RYMQ@1236|Gammaproteobacteria,46BCJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_4935_8 1288826.MSNKSG1_08493 2.16e-287 788.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4662G@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - ko:K19304 - - - - ko00000,ko01000,ko01002,ko01011 - - - OapA,Peptidase_M23 k141_4935_9 1396858.Q666_03590 3.12e-09 57.4 COG0811@1|root,COG0811@2|Bacteria 2|Bacteria U bacteriocin transport - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_13341_1 326297.Sama_2739 2.7e-06 49.3 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,2QA4Z@267890|Shewanellaceae 1236|Gammaproteobacteria D Tyrosine recombinase XerD xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_13341_2 1158762.KB898048_gene699 1.66e-33 120.0 2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,1SATY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13341_3 95619.PM1_0201030 0.000546 41.6 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA k141_18200_1 246200.SPO1675 4.22e-75 239.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria,4NAB9@97050|Ruegeria 28211|Alphaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_14029_2 317025.Tcr_0548 5.24e-28 103.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Belongs to the BolA IbaG family bolA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_8435_1 1288826.MSNKSG1_04816 3.48e-230 643.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_8435_2 1288826.MSNKSG1_04821 1.74e-47 154.0 COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria,465I3@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C k141_20316_1 1198232.CYCME_2286 6.05e-46 158.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,4604R@72273|Thiotrichales 72273|Thiotrichales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_20316_2 1502770.JQMG01000001_gene458 4.59e-39 144.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,2KMCV@206350|Nitrosomonadales 206350|Nitrosomonadales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_15439_2 748247.AZKH_2949 1.38e-61 199.0 COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,2VSJJ@28216|Betaproteobacteria,2KWYE@206389|Rhodocyclales 206389|Rhodocyclales C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - k141_7767_1 317025.Tcr_0394 6.43e-54 174.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,460KW@72273|Thiotrichales 72273|Thiotrichales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_11270_1 1149133.ppKF707_2749 0.000482 42.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1TCJ2@1236|Gammaproteobacteria,1YKDM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Creatinine amidohydrolase - - - - - - - - - - - - Creatininase k141_11270_2 1122201.AUAZ01000001_gene2492 1.44e-62 197.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_12628_1 927658.AJUM01000042_gene1768 6.96e-15 81.6 COG4733@1|root,COG4733@2|Bacteria,4PI1C@976|Bacteroidetes,2G1DF@200643|Bacteroidia,3XKWE@558415|Marinilabiliaceae 976|Bacteroidetes S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS k141_21037_1 998674.ATTE01000001_gene2263 7.03e-51 174.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,45ZZH@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_21037_2 228399.appser1_4530 8.18e-35 128.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1Y700@135625|Pasteurellales 135625|Pasteurellales I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_5685_2 1288826.MSNKSG1_06028 1.63e-131 385.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,464D2@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_16100_1 768671.ThimaDRAFT_3591 3.23e-41 143.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1S53U@1236|Gammaproteobacteria,1WXF9@135613|Chromatiales 135613|Chromatiales D Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_16100_3 1255043.TVNIR_2978 1.45e-75 236.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales 135613|Chromatiales K LysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_16810_1 1288826.MSNKSG1_04456 7.54e-75 236.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,464J1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_4936_1 89187.ISM_10621 4.72e-54 184.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2TS0S@28211|Alphaproteobacteria,46NKX@74030|Roseovarius 28211|Alphaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_15565_5 1278309.KB907103_gene989 4.19e-146 417.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,1XK99@135619|Oceanospirillales 135619|Oceanospirillales S membrane protein (homolog of Drosophila rhomboid) - - - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid k141_15565_6 1278309.KB907103_gene988 9.78e-211 585.0 COG0639@1|root,COG0639@2|Bacteria,1QE1Y@1224|Proteobacteria,1RRG9@1236|Gammaproteobacteria,1XHU1@135619|Oceanospirillales 135619|Oceanospirillales T Diadenosine tetraphosphatase and related serine threonine protein - - - - - - - - - - - - Metallophos k141_15565_7 1278309.KB907103_gene987 2.56e-09 56.6 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1XI7V@135619|Oceanospirillales 135619|Oceanospirillales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP ppnK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_14860_1 1278309.KB907099_gene2601 6.33e-57 190.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XIJJ@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_14860_2 1278309.KB907099_gene2602 2.54e-67 217.0 COG0439@1|root,COG0439@2|Bacteria,1R5XW@1224|Proteobacteria,1RYYE@1236|Gammaproteobacteria,1XIUC@135619|Oceanospirillales 135619|Oceanospirillales I Biotin carboxylase - - - - - - - - - - - - CPSase_L_D2 k141_12759_1 1121935.AQXX01000109_gene480 2.42e-87 284.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XHSN@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_14144_1 767434.Fraau_0102 1.81e-96 291.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RQ1X@1236|Gammaproteobacteria,1X4PU@135614|Xanthomonadales 135614|Xanthomonadales C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red k141_19038_1 1121406.JAEX01000014_gene2321 6.42e-33 117.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,42TS2@68525|delta/epsilon subdivisions,2WPZ5@28221|Deltaproteobacteria,2MCQX@213115|Desulfovibrionales 28221|Deltaproteobacteria G PFAM Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_2 k141_19038_2 1173026.Glo7428_4438 2.61e-05 48.9 29WN8@1|root,30I93@2|Bacteria,1GAIY@1117|Cyanobacteria 1117|Cyanobacteria S PrcB C-terminal - - - - - - - - - - - - PrcB_C k141_3689_1 1121904.ARBP01000002_gene7078 9.62e-69 225.0 COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,47N1D@768503|Cytophagia 976|Bacteroidetes M Dolichyl-phosphate-mannose-protein mannosyltransferase - - 2.4.2.43 ko:K07264 ko01503,map01503 M00721 R09773,R09774,R09781 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - - - LAB_N,PMT,PMT_2 k141_17628_1 1279017.AQYJ01000024_gene1175 1.14e-16 75.9 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,466TX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin,Rhodanese k141_17628_2 1232683.ADIMK_3041 4.65e-16 73.9 COG5007@1|root,COG5007@2|Bacteria,1PZMG@1224|Proteobacteria,1SGB5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the BolA IbaG family - - - - - - - - - - - - BolA k141_21163_2 231434.JQJH01000025_gene3262 4.09e-50 165.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,3NAZX@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Putative zinc- or iron-chelating domain MA20_15575 - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_21163_3 1502770.JQMG01000001_gene291 9.14e-09 58.9 COG5488@1|root,COG5488@2|Bacteria,1N5Z9@1224|Proteobacteria,2VU1W@28216|Betaproteobacteria,2KN5A@206350|Nitrosomonadales 206350|Nitrosomonadales S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 k141_21163_5 483219.LILAB_12355 4.06e-25 101.0 28R6X@1|root,2ZDKX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_1588_1 1005048.CFU_0383 1.09e-58 200.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,473VE@75682|Oxalobacteraceae 28216|Betaproteobacteria P monovalent cation proton kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_7875_1 1453503.AU05_07140 1.28e-156 449.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,1RNY9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E peptidase M24 - - - - - - - - - - - - Creatinase_N,Peptidase_M24 k141_177_1 1397527.Q670_04240 1.07e-160 458.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1XHZG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_177_2 323850.Shew_3576 8.7e-34 122.0 COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,1S0F8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cysteine dioxygenase - - - - - - - - - - - - CDO_I k141_10676_1 1288826.MSNKSG1_09188 1.1e-25 104.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,466AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_10676_2 1288826.MSNKSG1_09183 1.07e-153 431.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria,467S3@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2356 Endonuclease I endA - 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Ada_Zn_binding,Endonuclease_1 k141_10676_3 1288826.MSNKSG1_09178 9.49e-18 77.8 2EHHF@1|root,33B9C@2|Bacteria,1NM2H@1224|Proteobacteria,1SECY@1236|Gammaproteobacteria,46BWB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10676_4 1288826.MSNKSG1_09173 1.68e-228 630.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,466B8@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III, delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_10676_5 1288826.MSNKSG1_09168 6.86e-120 344.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE k141_20444_1 686340.Metal_0872 5.01e-123 379.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XDWG@135618|Methylococcales 135618|Methylococcales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_888_1 1278309.KB907105_gene1502 6.56e-43 142.0 2DN2D@1|root,32V5H@2|Bacteria,1N495@1224|Proteobacteria,1SAD6@1236|Gammaproteobacteria,1XKTH@135619|Oceanospirillales 135619|Oceanospirillales S Phasin protein - - - - - - - - - - - - Phasin_2 k141_888_2 316278.SynRCC307_2362 4.06e-64 198.0 COG0346@1|root,COG0346@2|Bacteria,1G504@1117|Cyanobacteria,1H0G4@1129|Synechococcus 1117|Cyanobacteria E Lactoylglutathione lyase gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_888_3 1278309.KB907105_gene1500 3.41e-104 310.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1XIY2@135619|Oceanospirillales 135619|Oceanospirillales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_888_4 1278309.KB907105_gene1498 1.56e-83 248.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1XRFK@135619|Oceanospirillales 135619|Oceanospirillales S RDD family - - - - - - - - - - - - RDD k141_21794_1 768671.ThimaDRAFT_2451 2.17e-99 320.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C k141_8572_1 743720.Psefu_4348 1.36e-68 228.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1YW8P@136845|Pseudomonas putida group 1236|Gammaproteobacteria K sigma-54 specific transcriptional regulator - - - ko:K11914,ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko02044,ko03000 - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_8572_2 1122599.AUGR01000002_gene3472 3.53e-201 578.0 COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,1XK52@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter - - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_8572_3 1122599.AUGR01000002_gene3473 1.31e-213 613.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,1XHV6@135619|Oceanospirillales 135619|Oceanospirillales V TIGRFAM ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD - - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_8572_4 1278309.KB907100_gene2223 1.79e-139 405.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RM90@1236|Gammaproteobacteria,1XHRT@135619|Oceanospirillales 135619|Oceanospirillales KT Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Sigma54_activat k141_16217_1 1278309.KB907110_gene3183 2.69e-159 455.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XHUY@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_16217_2 1278309.KB907110_gene3184 8.24e-96 297.0 COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,1RYNS@1236|Gammaproteobacteria,1XJSQ@135619|Oceanospirillales 135619|Oceanospirillales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 k141_12058_1 1266909.AUAG01000004_gene2101 6.14e-06 49.3 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1WXA2@135613|Chromatiales 135613|Chromatiales T TIGRFAM Diguanylate cyclase - - - - - - - - - - - - GGDEF,HisKA,PAS_3,Response_reg k141_12058_2 1535422.ND16A_0646 3.98e-38 144.0 COG0758@1|root,COG0758@2|Bacteria,1N2UI@1224|Proteobacteria 1224|Proteobacteria LU DNA mediated transformation - - - - - - - - - - - - - k141_19713_1 1120970.AUBZ01000003_gene164 1e-81 258.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,465NU@72275|Alteromonadaceae 1236|Gammaproteobacteria U general secretion pathway protein - - - - - - - - - - - - AAA_22 k141_19713_2 1121937.AUHJ01000009_gene1523 4.01e-12 65.9 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae 1236|Gammaproteobacteria G xylanase chitin deacetylase - - - - - - - - - - - - DUF3473,Polysacc_deac_1 k141_10677_1 571166.KI421509_gene3632 2.74e-15 70.1 COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,2UHB7@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Multiple resistance and pH regulation protein F - - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF k141_10677_2 388401.RB2150_16117 4.4e-37 130.0 COG1320@1|root,COG1320@2|Bacteria,1N75I@1224|Proteobacteria,2UETR@28211|Alphaproteobacteria 28211|Alphaproteobacteria P monovalent cation proton antiporter, MnhG PhaG subunit - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_10677_3 1333998.M2A_0554 0.000659 42.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,2U7UT@28211|Alphaproteobacteria,4BQH2@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Domain of unknown function (DUF4040) - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040 k141_20445_1 1382303.JPOM01000001_gene1528 1.11e-10 59.7 COG3293@1|root,COG3293@2|Bacteria,1RM2E@1224|Proteobacteria,2UBEA@28211|Alphaproteobacteria,2KHCZ@204458|Caulobacterales 204458|Caulobacterales L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 k141_20445_2 266835.14028286 3.45e-26 100.0 COG5421@1|root,COG5421@2|Bacteria,1N03U@1224|Proteobacteria,2UCI1@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG3293 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1_2 k141_21164_1 1123399.AQVE01000020_gene1702 7.94e-100 309.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,45ZSE@72273|Thiotrichales 72273|Thiotrichales C dihydrolipoamide dehydrogenase - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim k141_2999_1 765913.ThidrDRAFT_2321 4.59e-57 185.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales 135613|Chromatiales S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_2999_2 472759.Nhal_0548 3.6e-124 369.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_6453_1 395493.BegalDRAFT_0251 1.69e-118 358.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_6453_2 314278.NB231_14433 1.5e-117 358.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales 135613|Chromatiales K ribonuclease BN - - - ko:K07058 - - - - ko00000 - - - Rrf2,Virul_fac_BrkB k141_11387_1 1288826.MSNKSG1_05206 5.92e-264 763.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,4645X@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_11387_2 1288826.MSNKSG1_05201 7.86e-25 98.2 COG1802@1|root,COG1802@2|Bacteria,1RIE7@1224|Proteobacteria,1S6K0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - FCD,GntR k141_8573_1 545264.KB898745_gene1204 5.33e-55 185.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1WWHB@135613|Chromatiales 135613|Chromatiales E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_4390_1 1042375.AFPL01000019_gene202 9.05e-54 169.0 COG5470@1|root,COG5470@2|Bacteria,1PJI4@1224|Proteobacteria,1SFI4@1236|Gammaproteobacteria,46C35@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 k141_4390_2 1042375.AFPL01000019_gene201 3.6e-153 434.0 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1RY5G@1236|Gammaproteobacteria,46B36@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_4390_3 102129.Lepto7375DRAFT_2066 0.00072 43.1 COG1309@1|root,COG1309@2|Bacteria,1G7CD@1117|Cyanobacteria 1117|Cyanobacteria K Transcriptional regulator - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_13,TetR_N k141_14862_1 207954.MED92_13231 3.93e-55 177.0 2A49J@1|root,30SV1@2|Bacteria,1RF7U@1224|Proteobacteria,1S3TV@1236|Gammaproteobacteria,1XJMP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14862_2 1278309.KB907103_gene1040 4.55e-40 134.0 2ETJP@1|root,33M3F@2|Bacteria,1NH39@1224|Proteobacteria,1SGTE@1236|Gammaproteobacteria,1XMIE@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14862_3 1278309.KB907103_gene1039 7.04e-175 494.0 COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,1XI2F@135619|Oceanospirillales 135619|Oceanospirillales S ATP-NAD kinase - - - - - - - - - - - - NAD_kinase k141_5053_2 1248232.BANQ01000067_gene2273 8.27e-13 67.0 2AXXT@1|root,31PZ1@2|Bacteria,1QMMZ@1224|Proteobacteria,1TJXH@1236|Gammaproteobacteria,1Y1TI@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_5820_1 1278309.KB907103_gene1205 2.58e-133 380.0 COG3222@1|root,COG3222@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 k141_5820_2 1278309.KB907103_gene1204 2.08e-208 583.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XH2Z@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_1589_1 1286106.MPL1_06889 6.61e-183 519.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,45ZRY@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM glutamine synthetase, type I glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_10678_1 269799.Gmet_1779 7.48e-44 157.0 COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,42RCT@68525|delta/epsilon subdivisions,2WKJ9@28221|Deltaproteobacteria,43UJX@69541|Desulfuromonadales 28221|Deltaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Glutaredoxin k141_13453_1 1122599.AUGR01000014_gene653 5.28e-271 746.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XI4C@135619|Oceanospirillales 135619|Oceanospirillales G C4-dicarboxylate transport system - - - - - - - - - - - - DctM k141_13453_2 1278309.KB907100_gene2199 4.4e-34 120.0 COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria,1S2H9@1236|Gammaproteobacteria,1XJMX@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_21796_2 322710.Avin_35240 3.09e-36 138.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - DUF4010,MgtC k141_7877_1 1463858.JOHR01000004_gene1699 3.19e-48 164.0 COG0177@1|root,COG0177@2|Bacteria,2GNYB@201174|Actinobacteria 201174|Actinobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - - - - - - - - - - - k141_9920_1 1121374.KB891585_gene2123 1.41e-84 270.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_9920_2 1131553.JIBI01000029_gene2460 2.52e-249 708.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,372B6@32003|Nitrosomonadales 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily dppF - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_19040_1 1288826.MSNKSG1_08938 1.48e-141 401.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,464UP@72275|Alteromonadaceae 1236|Gammaproteobacteria S NIF3 (NGG1p interacting factor 3) ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - - - - - - - - - - NIF3 k141_19040_2 1288826.MSNKSG1_08943 2.17e-243 669.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,464SK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12060_1 666509.RCA23_c12040 7.72e-74 227.0 COG1024@1|root,COG1024@2|Bacteria,1MX21@1224|Proteobacteria,2TV87@28211|Alphaproteobacteria 28211|Alphaproteobacteria I 'PFAM Enoyl-CoA hydratase isomerase - - - ko:K16880 ko00365,ko01120,map00365,map01120 - R10210 RC00004,RC01903 ko00000,ko00001 - - - ECH_1 k141_179_1 448385.sce9157 1.17e-05 53.5 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,2YUND@29|Myxococcales 28221|Deltaproteobacteria P PEGA domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - PEGA,Plug,TonB_dep_Rec k141_15567_2 2340.JV46_02580 1.84e-28 112.0 COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,1S76Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_21166_1 396588.Tgr7_0763 1.03e-71 234.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_891_1 525897.Dbac_0346 1.34e-06 54.7 COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MADW@213115|Desulfovibrionales 28221|Deltaproteobacteria KT SMART Protein phosphatase - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_2,SSF,SpoIIE k141_13454_1 870187.Thini_3454 5.05e-83 261.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales 72273|Thiotrichales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_17629_1 41431.PCC8801_4246 4.79e-08 53.5 COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria 1117|Cyanobacteria S of the cupin superfamily - - - ko:K06995 - - - - ko00000 - - - Cupin_3 k141_17629_2 991.IW20_18420 1.28e-16 79.3 COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I17E@117743|Flavobacteriia,2NSUH@237|Flavobacterium 976|Bacteroidetes M Fasciclin - - - - - - - - - - - - Fasciclin k141_17629_3 1122201.AUAZ01000034_gene3507 7.1e-67 213.0 COG0404@1|root,COG0404@2|Bacteria,1N1G4@1224|Proteobacteria,1S3BD@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the GcvT family - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_20447_1 1279038.KB907345_gene3431 5.72e-05 46.2 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2UP6H@28211|Alphaproteobacteria,2JRF2@204441|Rhodospirillales 204441|Rhodospirillales T diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF k141_20447_2 395493.BegalDRAFT_2990 2.42e-61 202.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,45ZXR@72273|Thiotrichales 72273|Thiotrichales H Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - - - - - - - - - - HemN_C,Radical_SAM k141_16226_1 1288826.MSNKSG1_13752 3.2e-114 338.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,46495@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump VVA1228 - - - - - - - - - - - MatE k141_3703_1 94624.Bpet3138 1.03e-28 115.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VI49@28216|Betaproteobacteria,3T6TJ@506|Alcaligenaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_10058_3 1278309.KB907100_gene1858 5.28e-76 231.0 COG2980@1|root,COG2980@2|Bacteria,1QTC7@1224|Proteobacteria,1RXAE@1236|Gammaproteobacteria,1XMH2@135619|Oceanospirillales 135619|Oceanospirillales M Lipopolysaccharide-assembly - - - - - - - - - - - - LptE k141_13562_2 1123373.ATXI01000003_gene1284 3.33e-23 99.4 COG0318@1|root,COG0318@2|Bacteria,2GH7C@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria IQ AMP-binding enzyme C-terminal domain - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_19192_1 243233.MCA0969 6.02e-92 285.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1XDUX@135618|Methylococcales 135618|Methylococcales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_14963_1 439375.Oant_2655 1.97e-22 95.9 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,1J1XS@118882|Brucellaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_N,GST_N_3 k141_14963_2 292415.Tbd_1307 2.39e-16 73.2 2A022@1|root,30N4D@2|Bacteria,1PU9H@1224|Proteobacteria,2WARI@28216|Betaproteobacteria,1KRVX@119069|Hydrogenophilales 119069|Hydrogenophilales S Domain of unknown function (DUF1840) - - - - - - - - - - - - DUF1840 k141_4541_1 983545.Glaag_2120 2.23e-24 98.2 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,464UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Electron transfer flavoprotein etfB - - ko:K03521 - - - - ko00000 - - - ETF k141_4541_2 1294143.H681_12390 4.49e-68 216.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_12892_1 1288826.MSNKSG1_13082 1.64e-88 259.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S9TF@1236|Gammaproteobacteria,467NV@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09966 - - - - ko00000 - - - DUF2237 k141_12892_2 1288826.MSNKSG1_13077 0.0 1296.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,463YK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_12892_3 1288826.MSNKSG1_13072 3.28e-88 267.0 COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,1SE9G@1236|Gammaproteobacteria,46CAT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0666 FOG Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_3,Ank_4,Ank_5 k141_12892_4 1288826.MSNKSG1_13067 1.07e-263 722.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,464P0@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_2 k141_12892_5 1288826.MSNKSG1_13062 2.2e-66 202.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,468JG@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cycM - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_12892_6 1288826.MSNKSG1_13057 0.0 929.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,46503@72275|Alteromonadaceae 1236|Gammaproteobacteria S Rossmann fold nucleotide-binding protein ygdH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_12892_7 1288826.MSNKSG1_13052 0.0 927.0 COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,4664X@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 THUMP,ThiI k141_12892_8 1288826.MSNKSG1_13047 2.43e-238 655.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1S070@1236|Gammaproteobacteria,46A3M@72275|Alteromonadaceae 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_12892_9 1288826.MSNKSG1_13042 0.0 982.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_8064_1 887898.HMPREF0551_0522 1.37e-38 142.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,1K0SS@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM peptidase U62 modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_8064_2 105559.Nwat_0287 1.99e-122 365.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales 135613|Chromatiales P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_7307_1 278963.ATWD01000001_gene1916 1.9e-31 125.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - DUF4157 k141_1752_1 519989.ECTPHS_01379 5.23e-58 193.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_14245_2 562970.Btus_2968 3.47e-10 63.5 COG1715@1|root,COG1715@2|Bacteria,1VYP8@1239|Firmicutes 1239|Firmicutes V Mrr N-terminal domain - - - - - - - - - - - - Mrr_N k141_14245_3 1173263.Syn7502_00145 2.97e-202 580.0 COG0286@1|root,COG0286@2|Bacteria,1G70A@1117|Cyanobacteria 1117|Cyanobacteria V Type I restriction-modification system methyltransferase subunit - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HSDR_N_2,N6_Mtase k141_12193_2 572477.Alvin_0265 2.23e-43 148.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1WYDP@135613|Chromatiales 135613|Chromatiales K Ribosomal-protein-alanine acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_12193_3 1049564.TevJSym_am00800 6.56e-09 56.2 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria 1236|Gammaproteobacteria L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_5179_1 1288826.MSNKSG1_11668 5.22e-285 792.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4651T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_5179_2 1288826.MSNKSG1_11663 5.96e-206 570.0 COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,1S2YT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG1073 Hydrolases of the alpha beta superfamily yfhR - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_5179_3 1288826.MSNKSG1_11658 1e-211 598.0 28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,1RRQ0@1236|Gammaproteobacteria,464R0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 k141_5910_1 314278.NB231_15853 7.16e-75 236.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1WWUA@135613|Chromatiales 135613|Chromatiales M Lytic murein transglycosylase B - - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_20592_1 626887.J057_19040 3.66e-120 364.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,4661Y@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_20592_2 1288826.MSNKSG1_08628 3.85e-35 122.0 COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,1SH7I@1236|Gammaproteobacteria,468X0@72275|Alteromonadaceae 1236|Gammaproteobacteria N flagellar protein FlaG flaG - - ko:K06603 - - - - ko00000,ko02035 - - - FlaG k141_19193_1 870187.Thini_4082 1.56e-105 314.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,45ZXW@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_7308_1 371731.Rsw2DRAFT_0007 9.14e-78 239.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,1FB5G@1060|Rhodobacter 28211|Alphaproteobacteria J SpoU rRNA Methylase family trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - DUF559,SpoU_methylase k141_21959_1 1278309.KB907104_gene831 7.28e-84 249.0 COG3157@1|root,COG3157@2|Bacteria,1MXFB@1224|Proteobacteria,1RNKQ@1236|Gammaproteobacteria,1XMG1@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion system effector, Hcp - - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k141_21959_2 1278309.KB907104_gene832 8.98e-88 261.0 COG3521@1|root,COG3521@2|Bacteria,1PFDN@1224|Proteobacteria,1SXD2@1236|Gammaproteobacteria,1XMK2@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 - - - ko:K11906 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS-SciN k141_10059_2 760117.JN27_01475 5.16e-54 181.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,472Q2@75682|Oxalobacteraceae 28216|Betaproteobacteria I Transposase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase k141_21970_1 933262.AXAM01000016_gene166 4.39e-09 57.4 2EC3H@1|root,3362D@2|Bacteria,1NDXP@1224|Proteobacteria,42WQJ@68525|delta/epsilon subdivisions,2WRNF@28221|Deltaproteobacteria,2MKWZ@213118|Desulfobacterales 28221|Deltaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_5199_1 1163409.UUA_02126 2.94e-33 121.0 2A2U9@1|root,30R85@2|Bacteria,1PD1C@1224|Proteobacteria,1SY7T@1236|Gammaproteobacteria,1X7B8@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - LEA_2 k141_5199_2 1500893.JQNB01000001_gene267 0.00019 42.7 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1X364@135614|Xanthomonadales 135614|Xanthomonadales I acyl-coa dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_4552_1 396588.Tgr7_0185 7.55e-92 288.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_13576_2 1120970.AUBZ01000008_gene2461 1.27e-45 150.0 COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,467E8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 k141_13576_3 930169.B5T_01314 5.05e-45 153.0 2DZH7@1|root,32VAP@2|Bacteria,1N6FC@1224|Proteobacteria,1SABS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - TerB k141_13576_4 717773.Thicy_1077 8.78e-44 152.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,460DG@72273|Thiotrichales 72273|Thiotrichales V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_3828_1 1123399.AQVE01000002_gene2275 8.19e-22 89.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_1041_1 1266998.ATUJ01000010_gene641 8.58e-22 92.8 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2PU0P@265|Paracoccus 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_1041_2 935840.JAEQ01000024_gene4161 8.37e-95 292.0 COG0022@1|root,COG0508@1|root,COG0022@2|Bacteria,COG0508@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,43IG5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,Transket_pyr,Transketolase_C k141_8085_1 203122.Sde_3110 9.35e-20 94.0 COG0745@1|root,COG0745@2|Bacteria,1NFQQ@1224|Proteobacteria,1SFGH@1236|Gammaproteobacteria,46BZR@72275|Alteromonadaceae 1236|Gammaproteobacteria T RESPONSE REGULATOR receiver - - - - - - - - - - - - - k141_19841_1 1217656.F964_03381 4.73e-48 179.0 COG0454@1|root,COG1040@1|root,COG0456@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,3NM26@468|Moraxellaceae 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - - k141_12907_1 999141.GME_16097 4.12e-36 128.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1XKER@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_5926_1 4155.Migut.D01250.1.p 5.88e-102 296.0 COG1143@1|root,KOG3256@2759|Eukaryota,37YQF@33090|Viridiplantae,3GCUY@35493|Streptophyta,44RDM@71274|asterids 35493|Streptophyta C NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient ndhI GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0055114 1.6.5.3 ko:K05580 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Fer4 k141_13577_1 236097.ADG881_2038 8.79e-59 183.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XJH4@135619|Oceanospirillales 135619|Oceanospirillales K at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) glnK-2 - - ko:K04752 - - - - ko00000 - - - P-II k141_19211_1 322710.Avin_42560 2.43e-100 317.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_18449_1 870187.Thini_0172 3.81e-265 753.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_4553_1 1552758.NC00_19585 3.92e-10 62.8 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1X4MX@135614|Xanthomonadales 135614|Xanthomonadales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_4553_2 1198232.CYCME_1988 8.02e-26 105.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,460J5@72273|Thiotrichales 72273|Thiotrichales M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_20607_1 1278309.KB907102_gene186 6.63e-156 447.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XIX4@135619|Oceanospirillales 135619|Oceanospirillales T Bacterial regulatory protein, Fis family - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_15692_1 1238182.C882_0257 1.69e-83 274.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JPRP@204441|Rhodospirillales 204441|Rhodospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_17789_1 1278309.KB907100_gene1872 2.9e-31 119.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XI5M@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_17789_2 1278309.KB907100_gene1873 1.23e-150 429.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XIEE@135619|Oceanospirillales 135619|Oceanospirillales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k141_17789_3 1278309.KB907100_gene1874 8.02e-190 533.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1XIS6@135619|Oceanospirillales 135619|Oceanospirillales M Lytic murein transglycosylase B mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_17789_4 1278309.KB907100_gene1875 8.09e-244 673.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1XHKP@135619|Oceanospirillales 135619|Oceanospirillales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_17789_5 1278309.KB907100_gene1876 3.09e-278 773.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XHM0@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_11513_1 1499967.BAYZ01000095_gene4114 5.48e-37 145.0 COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria 2|Bacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_3829_1 1158756.AQXQ01000008_gene2449 1.98e-94 294.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_14269_2 1158762.KB898040_gene1412 4.13e-30 116.0 COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,1WVYE@135613|Chromatiales 135613|Chromatiales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily rlmM - 2.1.1.186 ko:K06968 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_12909_1 717785.HYPMC_4516 4.48e-20 93.2 COG3735@1|root,COG3735@2|Bacteria,1RBFT@1224|Proteobacteria,2U5YM@28211|Alphaproteobacteria,3N7DH@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB k141_10823_1 1288826.MSNKSG1_09468 1.95e-155 454.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465BW@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl propionyl-CoA carboxylase, alpha subunit mccA - 6.4.1.4,6.4.1.5 ko:K01968,ko:K13777 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R03494,R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_10823_2 1288826.MSNKSG1_09463 3.81e-187 521.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,4670X@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase atuE - 4.2.1.57 ko:K13779 ko00281,map00281 - R03493 RC00941 ko00000,ko00001,ko01000 - - - ECH_1 k141_10823_3 1288826.MSNKSG1_09458 1.01e-229 635.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RW1Q@1236|Gammaproteobacteria,4663X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases atuD - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_1042_1 1042375.AFPL01000019_gene193 6.77e-67 224.0 COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria,464TA@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpd_2 - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_5201_1 1123053.AUDG01000008_gene3603 5.05e-34 126.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,1WZD6@135613|Chromatiales 135613|Chromatiales L PFAM D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k141_5201_2 228410.NE0299 1.55e-63 211.0 COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,2WFIE@28216|Betaproteobacteria,372YN@32003|Nitrosomonadales 28216|Betaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_2433_1 391589.RGAI101_986 2.24e-138 416.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2P1NC@2433|Roseobacter 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_19842_2 95619.PM1_0222280 1.6e-67 212.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q hydratase mhpD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0008150,GO:0008152,GO:0008684,GO:0009056,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914 4.2.1.80 ko:K02554 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R02601,R04781 RC00750,RC01213 br01602,ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0386,iECO26_1355.ECO26_0386,iECW_1372.ECW_m0428,iEKO11_1354.EKO11_3492,iEcE24377_1341.EcE24377A_0374,iEcHS_1320.EcHS_A0414,iWFL_1372.ECW_m0428 FAA_hydrolase k141_3173_1 1278309.KB907101_gene394 7.21e-75 231.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_3173_2 1278309.KB907101_gene393 3.78e-282 791.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XI50@135619|Oceanospirillales 135619|Oceanospirillales S exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_12218_2 1278309.KB907099_gene2580 0.0 896.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1XI4R@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - - ko:K20035 ko00920,map00920 - R11130 RC03363 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_7320_1 1178482.BJB45_05755 2.59e-09 55.8 COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1XKZ7@135619|Oceanospirillales 135619|Oceanospirillales S YcgL domain-containing protein - - - ko:K09902 - - - - ko00000 - - - YcgL k141_7320_2 1336233.JAEH01000032_gene496 2.23e-41 138.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,2QCB5@267890|Shewanellaceae 1236|Gammaproteobacteria T Belongs to the BolA IbaG family bolA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_7320_3 338969.Rfer_0831 3.41e-220 637.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,4ACBR@80864|Comamonadaceae 28216|Betaproteobacteria O AAA domain - - - - - - - - - - - - AAA_32,Lon_C k141_13580_1 192952.MM_0518 1.4e-24 107.0 COG2203@1|root,arCOG02361@2157|Archaea,2Y7N6@28890|Euryarchaeota,2NBKD@224756|Methanomicrobia 224756|Methanomicrobia T GAF domain - - - - - - - - - - - - HATPase_c,HisKA_2,PAS_9 k141_21297_1 558169.AGAV01000024_gene15 4.79e-21 97.4 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components ytlA GO:0003674,GO:0005215 - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_3174_1 388051.AUFE01000006_gene1211 1.38e-05 50.8 COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,1KGMB@119060|Burkholderiaceae 28216|Betaproteobacteria T Serine/threonine phosphatases, family 2C, catalytic domain pphA - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_3174_2 1121940.AUDZ01000009_gene2085 1.24e-15 73.9 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XI8X@135619|Oceanospirillales 135619|Oceanospirillales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_12219_1 666685.R2APBS1_0691 2.75e-54 189.0 COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria,1X9PB@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyl hydrolase family 65 central catalytic domain - - - - - - - - - - - - Glyco_hydro_65N,Glyco_hydro_65m k141_10824_1 1288826.MSNKSG1_14847 6.11e-137 387.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,4677N@72275|Alteromonadaceae 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_1902_1 991905.SL003B_2137 3.3e-48 162.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U2DD@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_1902_2 1123518.ARWI01000001_gene1249 1.01e-17 86.3 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,460K4@72273|Thiotrichales 72273|Thiotrichales C Rubredoxin - - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_9483_1 1095743.HMPREF1054_1772 9.68e-40 149.0 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,1RRH5@1236|Gammaproteobacteria,1Y87N@135625|Pasteurellales 135625|Pasteurellales S Bacteriophage tail assembly protein - - - - - - - - - - - - Terminase_GpA k141_6037_1 338963.Pcar_0385 1.73e-99 312.0 COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2X75C@28221|Deltaproteobacteria,43UGU@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Secretin N-terminal domain - - - ko:K02453,ko:K12282 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N_2 k141_13078_1 1288826.MSNKSG1_17341 3.74e-73 219.0 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,46C1H@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_13078_2 1288826.MSNKSG1_17336 0.0 1701.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_13078_3 1288826.MSNKSG1_17331 2.06e-79 236.0 29832@1|root,2ZV91@2|Bacteria,1P8Q5@1224|Proteobacteria,1SVHD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13078_4 1396858.Q666_00415 3.23e-232 652.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,467IQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_13078_5 1288826.MSNKSG1_17321 7.27e-265 726.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,464NP@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG5008 Tfp pilus assembly protein, ATPase PilU pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_22095_1 1288826.MSNKSG1_15367 1.01e-77 243.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,46546@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050662,GO:0051287,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k141_22095_2 1288826.MSNKSG1_15362 6.96e-110 317.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,46AS7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit nuoE GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iYL1228.KPN_02675 2Fe-2S_thioredx k141_22095_3 1288826.MSNKSG1_15357 0.0 1185.0 COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,465ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECDH10B_1368.ECDH10B_2448,iECDH1ME8569_1439.ECDH1ME8569_2223,iETEC_1333.ETEC_2421,iEcDH1_1363.EcDH1_1371,iPC815.YPO2553,iUMNK88_1353.UMNK88_2836 Complex1_30kDa,Complex1_49kDa k141_22095_4 1288826.MSNKSG1_15352 7.79e-163 455.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,469EA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051179,GO:0051234,GO:0051536,GO:0051539,GO:0051540,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iYL1228.KPN_02677 Oxidored_q6 k141_22095_5 1288826.MSNKSG1_15347 1.36e-90 265.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,46AXU@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2288,iAF1260.b2288,iAPECO1_1312.APECO1_4277,iB21_1397.B21_02173,iBWG_1329.BWG_2062,iE2348C_1286.E2348C_2428,iEC042_1314.EC042_2529,iEC55989_1330.EC55989_2532,iECABU_c1320.ECABU_c26200,iECBD_1354.ECBD_1373,iECB_1328.ECB_02213,iECDH10B_1368.ECDH10B_2450,iECDH1ME8569_1439.ECDH1ME8569_2225,iECD_1391.ECD_02213,iECED1_1282.ECED1_2752,iECH74115_1262.ECH74115_3427,iECIAI1_1343.ECIAI1_2362,iECIAI39_1322.ECIAI39_2435,iECO103_1326.ECO103_2752,iECO26_1355.ECO26_3276,iECOK1_1307.ECOK1_2521,iECP_1309.ECP_2327,iECS88_1305.ECS88_2435,iECSE_1348.ECSE_2545,iECSP_1301.ECSP_3162,iECUMN_1333.ECUMN_2627,iECW_1372.ECW_m2476,iECs_1301.ECs3172,iEKO11_1354.EKO11_1479,iETEC_1333.ETEC_2423,iEcDH1_1363.EcDH1_1369,iEcE24377_1341.EcE24377A_2581,iEcHS_1320.EcHS_A2437,iEcSMS35_1347.EcSMS35_2442,iEcolC_1368.EcolC_1364,iG2583_1286.G2583_2825,iJO1366.b2288,iJR904.b2288,iLF82_1304.LF82_1539,iNRG857_1313.NRG857_11585,iSBO_1134.SBO_2321,iSDY_1059.SDY_2484,iSFV_1184.SFV_2355,iSF_1195.SF2364,iSFxv_1172.SFxv_2608,iSSON_1240.SSON_2345,iS_1188.S2499,iSbBS512_1146.SbBS512_E2664,iUMN146_1321.UM146_05375,iUTI89_1310.UTI89_C2568,iWFL_1372.ECW_m2476,iY75_1357.Y75_RS11995,ic_1306.c2829 Oxidored_q4 k141_22095_6 1288826.MSNKSG1_15317 1.33e-75 227.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1SCFP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_22095_7 1288826.MSNKSG1_15257 0.0 1083.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1RMCA@1236|Gammaproteobacteria,4642T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain nhaP2 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006884,GO:0008150,GO:0008324,GO:0008361,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071840,GO:0071944,GO:0090066,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - CorC_HlyC,Na_H_Exchanger,TrkA_C k141_22095_8 1288826.MSNKSG1_15252 1.82e-124 355.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,4682Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_27405 - - - - - - - - - - - YkuD k141_10249_1 1304275.C41B8_06297 1.2e-34 134.0 COG3659@1|root,COG3659@2|Bacteria,1PI63@1224|Proteobacteria,1S9JZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M PFAM Carbohydrate-selective porin OprB - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB k141_19984_1 1049564.TevJSym_au00160 5.77e-94 292.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_17966_1 395493.BegalDRAFT_2870 4.85e-75 231.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,461ZC@72273|Thiotrichales 72273|Thiotrichales IQ KR domain - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_17966_2 1195246.AGRI_13550 1.84e-13 67.4 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,46782@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_1903_1 1336233.JAEH01000010_gene2615 8.92e-13 73.9 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,2Q96X@267890|Shewanellaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_9484_1 1232410.KI421426_gene1373 1.13e-28 115.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,43U78@69541|Desulfuromonadales 28221|Deltaproteobacteria L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_15112_1 1454202.PPBDW_20075___1 8.53e-87 265.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1XTQ1@135623|Vibrionales 135623|Vibrionales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_5408_2 1288826.MSNKSG1_16186 6.03e-191 533.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,464H5@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis gtrB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 k141_12400_2 1163617.SCD_n01494 5.57e-26 101.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VWRY@28216|Betaproteobacteria 28216|Betaproteobacteria C Succinate dehydrogenase, cytochrome b556 subunit - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_18606_1 105559.Nwat_2337 2.26e-168 484.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WX93@135613|Chromatiales 135613|Chromatiales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_18606_2 1349767.GJA_4125 4e-19 88.2 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,2VMUW@28216|Betaproteobacteria,475ES@75682|Oxalobacteraceae 28216|Betaproteobacteria T signal transduction - - - - - - - - - - - - HDOD k141_17220_1 1288826.MSNKSG1_16841 7.56e-07 49.7 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T423@1236|Gammaproteobacteria,46DF3@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_17220_2 1288826.MSNKSG1_16846 7.91e-104 300.0 COG0784@1|root,COG0784@2|Bacteria,1RDJG@1224|Proteobacteria,1T4JV@1236|Gammaproteobacteria,4674W@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Response_reg k141_1904_1 1237149.C900_00743 0.000146 48.1 COG0784@1|root,COG0784@2|Bacteria,4NHFX@976|Bacteroidetes,47YCW@768503|Cytophagia 976|Bacteroidetes T PAS domain - - - - - - - - - - - - PAS_3,PAS_8,PAS_9,Response_reg k141_21447_1 1049564.TevJSym_ag00420 6.97e-68 229.0 COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,1RZM1@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT Chemoreceptor zinc-binding domain - - - - - - - - - - - - CZB,MCPsignal k141_21447_2 62928.azo3476 3.72e-53 172.0 COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,2VQ6H@28216|Betaproteobacteria,2KW2X@206389|Rhodocyclales 206389|Rhodocyclales KT PAS fold - - - - - - - - - - - - PAS_3 k141_10250_1 1123399.AQVE01000020_gene1697 4.37e-21 90.9 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,4609A@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_10250_2 523791.Kkor_0352 1.27e-86 262.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1XMSX@135619|Oceanospirillales 135619|Oceanospirillales F COG1428 Deoxynucleoside kinases - - - - - - - - - - - - dNK k141_11650_1 83406.HDN1F_01240 4.58e-68 220.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_3317_1 1337093.MBE-LCI_1441 4.28e-42 152.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2P84Q@245186|Loktanella 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_3317_2 367336.OM2255_04445 5.76e-79 244.0 COG0583@1|root,COG0583@2|Bacteria,1MV5N@1224|Proteobacteria,2TRAX@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator MA20_05050 - - - - - - - - - - - HTH_1,LysR_substrate k141_10981_1 697282.Mettu_2396 2.25e-117 343.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XDPQ@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF2797) - - - - - - - - - - - - DUF2797 k141_15864_2 994573.T472_0213310 1.33e-109 323.0 COG0457@1|root,COG0457@2|Bacteria,1UIVP@1239|Firmicutes,25GJ8@186801|Clostridia,36V6U@31979|Clostridiaceae 186801|Clostridia S Rifampin ADP-ribosyl transferase - - - - - - - - - - - - Arr-ms k141_522_1 1384054.N790_05735 1.26e-10 60.5 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1X89W@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_522_2 187272.Mlg_2861 3.28e-135 387.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_522_3 498211.CJA_3478 1.02e-55 193.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1FH5N@10|Cellvibrio 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_17968_1 765912.Thimo_0935 3.93e-66 216.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales 135613|Chromatiales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_17221_1 945550.VISI1226_20405 6.29e-29 107.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XWV4@135623|Vibrionales 135623|Vibrionales J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_1235_2 357804.Ping_2702 2.77e-21 102.0 COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZ2Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,MASE1,NMT1,PAS,PAS_9,SBP_bac_3 k141_6705_1 1278309.KB907099_gene3086 1.05e-82 262.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XHD0@135619|Oceanospirillales 135619|Oceanospirillales T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_2,sCache_2 k141_6705_2 1232683.ADIMK_3734 1.29e-101 306.0 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,4657U@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_15865_1 488538.SAR116_2106 2.21e-112 326.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2TTE2@28211|Alphaproteobacteria,4BPV1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain ttrB - - ko:K00124,ko:K21308 ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200 - R00519,R11487 RC00168,RC02796 ko00000,ko00001 - - - Fer4_11,Fer4_3,Fer4_4 k141_11651_1 589865.DaAHT2_0631 2.08e-31 124.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales 28221|Deltaproteobacteria M Mechanosensitive ion channel mscS-2 - - - - - - - - - - - MS_channel k141_22098_1 1288826.MSNKSG1_13557 7.47e-55 184.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RQ5E@1236|Gammaproteobacteria,466CU@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG1352 Methylase of chemotaxis methyl-accepting proteins pilK - 2.1.1.80 ko:K00575,ko:K02661 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035,ko02044 - - - CheR,CheR_N k141_12401_1 867900.Celly_1042 3.03e-10 64.3 COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,1HX7U@117743|Flavobacteriia,1F8WN@104264|Cellulophaga 976|Bacteroidetes L COGs COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair umuC - - ko:K03502 - - - - ko00000,ko03400 - - - DUF4113,IMS,IMS_C k141_12401_2 396588.Tgr7_3074 5.28e-74 228.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_3951_1 1232683.ADIMK_2558 7.34e-233 654.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,46482@72275|Alteromonadaceae 1236|Gammaproteobacteria P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_3951_2 1278309.KB907105_gene1483 5.48e-278 767.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XI6W@135619|Oceanospirillales 135619|Oceanospirillales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_3951_3 1232683.ADIMK_2560 3.45e-107 322.0 COG0348@1|root,COG0348@2|Bacteria,1MWZ4@1224|Proteobacteria,1RQZX@1236|Gammaproteobacteria,469GX@72275|Alteromonadaceae 1236|Gammaproteobacteria C IG-like fold at C-terminal of FixG, putative oxidoreductase - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_6039_1 868864.Dester_0461 0.000798 47.8 COG0810@1|root,COG3039@1|root,COG0810@2|Bacteria,COG3039@2|Bacteria,2G459@200783|Aquificae 200783|Aquificae L SPTR Transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1 k141_6039_2 396588.Tgr7_1108 1.1e-72 219.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1S73Y@1236|Gammaproteobacteria,1X24K@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_15114_1 1049564.TevJSym_bg00250 7.33e-58 196.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1J4NX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P von Willebrand factor (vWF) type A domain norD - - ko:K02448 - - R00294 RC02794 ko00000 3.D.4.10 - - VWA,VWA_2 k141_15114_2 1185652.USDA257_c39070 1.84e-20 93.2 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria,4BCBS@82115|Rhizobiaceae 28211|Alphaproteobacteria CK FMN_bind nosR - - ko:K19339 - - - - ko00000,ko03000 - - - FMN_bind,Fer4_5 k141_20707_1 203122.Sde_3116 1.42e-10 59.3 2EJYG@1|root,33DP3@2|Bacteria,1NIGJ@1224|Proteobacteria,1SH50@1236|Gammaproteobacteria,46C7C@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13100_2 2340.JV46_11900 5.57e-86 261.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1J5J9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the dihydroorotate dehydrogenase family pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,NAD_binding_1 k141_8236_1 1278309.KB907107_gene1679 6.37e-240 678.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XHET@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_15130_1 1353537.TP2_11575 9.49e-35 126.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,2XM94@285107|Thioclava 28211|Alphaproteobacteria S Peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_19985_1 1288826.MSNKSG1_08458 2.19e-125 363.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_19985_2 1288826.MSNKSG1_08453 3.06e-135 384.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,4648J@72275|Alteromonadaceae 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_19985_3 1288826.MSNKSG1_08448 9.29e-111 318.0 COG5404@1|root,COG5404@2|Bacteria,1RD22@1224|Proteobacteria,1RYWE@1236|Gammaproteobacteria,469AE@72275|Alteromonadaceae 1236|Gammaproteobacteria D Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division sulA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0010564,GO:0010948,GO:0031333,GO:0031668,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0033554,GO:0034260,GO:0043086,GO:0043087,GO:0043254,GO:0044087,GO:0044092,GO:0045786,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051302,GO:0051336,GO:0051346,GO:0051716,GO:0051726,GO:0051782,GO:0065007,GO:0065009,GO:0071496,GO:1903664,GO:1903665,GO:2000241,GO:2000242,GO:2000244,GO:2000245 - ko:K13053 - - - - ko00000,ko03036 - - - SulA k141_19985_4 1288826.MSNKSG1_08443 2.35e-54 170.0 2EHUF@1|root,33BK2@2|Bacteria,1NMAC@1224|Proteobacteria,1SGY0@1236|Gammaproteobacteria,46950@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19985_6 1288826.MSNKSG1_08438 0.0 877.0 28H52@1|root,2ZADT@2|Bacteria,1R8NH@1224|Proteobacteria,1RQUB@1236|Gammaproteobacteria,46DG6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_19985_8 1288826.MSNKSG1_08428 0.0 913.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,464PS@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleQ - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_7499_1 1278309.KB907102_gene119 1.15e-63 200.0 COG2755@1|root,COG2755@2|Bacteria,1RDVJ@1224|Proteobacteria,1T0DW@1236|Gammaproteobacteria,1XRQC@135619|Oceanospirillales 135619|Oceanospirillales E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 k141_7499_2 1278309.KB907102_gene118 4.99e-78 235.0 COG1495@1|root,COG1495@2|Bacteria,1PSD8@1224|Proteobacteria,1TAIR@1236|Gammaproteobacteria,1XKDA@135619|Oceanospirillales 135619|Oceanospirillales O Disulfide bond formation protein DsbB - - - - - - - - - - - - DsbB k141_7499_3 1278309.KB907102_gene117 2.34e-150 432.0 COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1S271@1236|Gammaproteobacteria,1XM94@135619|Oceanospirillales 135619|Oceanospirillales S small GTP-binding protein - - - - - - - - - - - - ATP_bind_1 k141_7499_4 1278309.KB907102_gene116 7.43e-31 109.0 2EH9I@1|root,33B1E@2|Bacteria,1PC99@1224|Proteobacteria,1SG4G@1236|Gammaproteobacteria,1XRG2@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2788) - - - - - - - - - - - - DUF2788 k141_18632_1 1278309.KB907100_gene2087 1.75e-128 369.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XJ73@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_18632_2 1298593.TOL_0285 8.47e-82 256.0 COG0463@1|root,COG0463@2|Bacteria,1RFXT@1224|Proteobacteria,1S5PY@1236|Gammaproteobacteria,1XP92@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyltransferase family 92 - - - - - - - - - - - - Glyco_tranf_2_4 k141_20713_1 1304878.AUGD01000019_gene1206 1.26e-16 81.6 COG0517@1|root,COG0517@2|Bacteria,1NY5H@1224|Proteobacteria,2U1GG@28211|Alphaproteobacteria,3JTNC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S BON domain MA20_38110 - - - - - - - - - - - BON,CBS k141_2010_2 1165841.SULAR_03053 4.59e-87 263.0 COG2191@1|root,COG2191@2|Bacteria,1NX7R@1224|Proteobacteria,430UJ@68525|delta/epsilon subdivisions 1224|Proteobacteria C FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - - - - - - - - - - FmdE k141_4852_2 1163408.UU9_13713 2.66e-27 105.0 COG0330@1|root,COG0330@2|Bacteria,1QCKN@1224|Proteobacteria,1T8BI@1236|Gammaproteobacteria,1X7V5@135614|Xanthomonadales 135614|Xanthomonadales O COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - - - - - - - - - - Band_7 k141_20033_1 1469613.JT55_02000 1.07e-68 214.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,3FD47@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_20033_2 371731.Rsw2DRAFT_0084 6.47e-18 81.6 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,1FBIK@1060|Rhodobacter 28211|Alphaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_7593_1 583355.Caka_0683 2.36e-21 93.6 COG3209@1|root,COG3209@2|Bacteria,46UCN@74201|Verrucomicrobia 74201|Verrucomicrobia M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - RHS_repeat,VCBS k141_7593_2 1122225.AULQ01000002_gene639 9.92e-09 63.5 COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia 976|Bacteroidetes M RHS repeat-associated core domain protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_13928_1 1121403.AUCV01000009_gene1455 7.51e-32 128.0 COG3899@1|root,COG4191@1|root,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2WJNS@28221|Deltaproteobacteria 28221|Deltaproteobacteria KLT AAA ATPase domain - - - - - - - - - - - - AAA_16,GAF,HATPase_c,Pkinase k141_20827_2 1278309.KB907102_gene105 1.23e-265 732.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XHCZ@135619|Oceanospirillales 135619|Oceanospirillales J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_20827_4 553217.ENHAE0001_0021 3.21e-18 78.6 COG2040@1|root,COG2040@2|Bacteria,1NB5Y@1224|Proteobacteria,1SDNW@1236|Gammaproteobacteria,3NP9X@468|Moraxellaceae 1236|Gammaproteobacteria E Protein of unknown function (DUF2789) - - - - - - - - - - - - DUF2789 k141_20827_5 1278309.KB907102_gene102 2.44e-53 174.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1XIA7@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0246 family - - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_20054_1 1288826.MSNKSG1_15706 1.63e-286 785.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,465T8@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Pyr_redox_2 k141_20054_2 1288826.MSNKSG1_15701 0.0 1670.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,4656K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0008942,GO:0009061,GO:0009344,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0020037,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044464,GO:0045333,GO:0046857,GO:0046906,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051536,GO:0051540,GO:0055114,GO:0097159,GO:0098809,GO:1901265,GO:1901363 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3849 Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Rieske_2 k141_20054_3 1288826.MSNKSG1_15696 2.11e-80 238.0 COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,1S9F1@1236|Gammaproteobacteria,468J2@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske_2 k141_14531_1 1288826.MSNKSG1_11813 2.98e-75 226.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,466RT@72275|Alteromonadaceae 1236|Gammaproteobacteria O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB k141_14531_2 1288826.MSNKSG1_11803 0.0 958.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_14531_3 1288826.MSNKSG1_11798 5.78e-100 290.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4675X@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2867 Oligoketide cyclase lipid transport protein ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - - - - - - - - - - Polyketide_cyc k141_14531_4 1288826.MSNKSG1_11793 6.96e-57 177.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,468GE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0125 (RnfH) family rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_14531_5 1288826.MSNKSG1_11788 8.41e-74 221.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,468DR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_14531_6 1288826.MSNKSG1_11783 2.41e-95 278.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,4674B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_14531_7 1288826.MSNKSG1_11778 0.0 1020.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,4643D@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_14531_8 1288826.MSNKSG1_11773 1.97e-110 321.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,467BX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_14531_9 1288826.MSNKSG1_11768 0.0 1148.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,4644X@72275|Alteromonadaceae 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_14531_10 1288826.MSNKSG1_11763 6.49e-248 683.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,464JW@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_14531_11 1288826.MSNKSG1_11758 4.64e-185 515.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,464XD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0035 DapB_C,DapB_N k141_14531_12 1288826.MSNKSG1_11753 3.92e-187 524.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,465QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k141_8981_1 754476.Q7A_1619 1.59e-09 65.1 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,460BU@72273|Thiotrichales 72273|Thiotrichales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3 k141_2731_1 1380394.JADL01000008_gene3594 1.72e-75 237.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales 204441|Rhodospirillales EP Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_17362_1 998674.ATTE01000001_gene2587 3.81e-136 418.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales 72273|Thiotrichales F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_16675_1 1239962.C943_02553 7.78e-33 123.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_16675_2 1519464.HY22_12075 4.97e-56 197.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 k141_10454_1 580332.Slit_0143 4.16e-37 128.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria 28216|Betaproteobacteria P Rhodanese domain protein pspE2 - - - - - - - - - - - Rhodanese k141_14532_1 395493.BegalDRAFT_1308 1.03e-18 88.6 COG3735@1|root,COG3735@2|Bacteria,1RBFT@1224|Proteobacteria 1224|Proteobacteria S PFAM GumN family protein - - - ko:K09973 - - - - ko00000 - - - TraB k141_11753_1 153721.MYP_2128 2.44e-14 72.0 COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,47NST@768503|Cytophagia 976|Bacteroidetes O TIGRFAM universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_11753_2 1408813.AYMG01000004_gene4533 7.84e-40 136.0 28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1IS0K@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2480) - - - - - - - - - - - - DUF2480 k141_8982_1 981336.F944_01730 8.82e-59 207.0 COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,1RQH5@1236|Gammaproteobacteria,3NKDP@468|Moraxellaceae 1236|Gammaproteobacteria L CRISPR-associated helicase, Cas3 cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - ResIII k141_6220_2 870187.Thini_3995 4.35e-84 258.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,462Q9@72273|Thiotrichales 72273|Thiotrichales L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_6220_3 522306.CAP2UW1_2659 1.72e-10 59.3 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria 28216|Betaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789,ko:K14742 - - - - ko00000,ko01000,ko03009,ko03016 - - - Acetyltransf_1,Peptidase_M22 k141_18790_1 1298593.TOL_0175 6.4e-64 218.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XIKC@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_9657_1 439497.RR11_2727 2.24e-65 211.0 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2TR29@28211|Alphaproteobacteria,4NAF3@97050|Ruegeria 28211|Alphaproteobacteria E Aminotransferase class I and II patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_2025_1 1502852.FG94_04372 8.76e-06 50.8 COG3134@1|root,COG3134@2|Bacteria,1PV9R@1224|Proteobacteria,2WB69@28216|Betaproteobacteria,4753N@75682|Oxalobacteraceae 28216|Betaproteobacteria S Outer membrane lipoprotein - - - - - - - - - - - - Rick_17kDa_Anti k141_2025_3 1304275.C41B8_10368 4.58e-37 129.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria IV02_29925 - - - - - - - - - - - DUF1820 k141_11754_1 1049564.TevJSym_au00160 9.7e-106 324.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_20057_1 857087.Metme_4024 5.62e-17 87.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XEBN@135618|Methylococcales 135618|Methylococcales NU COG3170 Tfp pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - k141_657_1 666509.RCA23_c29420 5.99e-126 370.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_657_2 1288963.ADIS_4313 2.14e-08 56.6 COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,47JGK@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory helix-turn-helix protein, lysR family oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_20829_1 1278309.KB907103_gene1022 3.03e-175 523.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XHMF@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_6221_2 261292.Nit79A3_2876 5.46e-104 304.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2VM7I@28216|Betaproteobacteria,371XK@32003|Nitrosomonadales 28216|Betaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR k141_8985_1 767434.Fraau_2980 3.01e-82 267.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,1X4R9@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k141_17364_1 998088.B565_1884 1.76e-53 178.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1Y4BS@135624|Aeromonadales 135624|Aeromonadales O Glycoprotease family - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_17364_2 1000565.METUNv1_00432 1.27e-26 109.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,2KV34@206389|Rhodocyclales 206389|Rhodocyclales KL helicase dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 k141_6222_1 1121935.AQXX01000106_gene548 5.42e-41 141.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1XJXU@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the UPF0301 (AlgH) family algH - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_2735_1 861299.J421_1050 5.62e-07 50.1 COG1881@1|root,COG1881@2|Bacteria,1ZU1T@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP k141_2735_2 998674.ATTE01000001_gene4107 3.32e-74 231.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,461TV@72273|Thiotrichales 72273|Thiotrichales V ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_14534_2 395493.BegalDRAFT_2219 8.35e-08 63.9 COG1572@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4886@1|root,COG4932@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales 72273|Thiotrichales U Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - - k141_20830_1 1120999.JONM01000004_gene3716 2.08e-43 154.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,2KPQD@206351|Neisseriales 206351|Neisseriales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k141_20830_2 105559.Nwat_3126 3.16e-102 315.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales 135613|Chromatiales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_18791_2 1288826.MSNKSG1_09143 9.41e-108 310.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_18791_3 1288826.MSNKSG1_09148 1.32e-169 476.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4658M@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorC corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_17365_1 1288826.MSNKSG1_14992 3.12e-128 373.0 COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,1RMHC@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_4 k141_17365_2 1288826.MSNKSG1_14987 2.28e-57 182.0 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,46751@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems scoP - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_15206_1 1278309.KB907101_gene466 7.46e-68 214.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_15206_2 1278309.KB907101_gene473 2.03e-90 266.0 COG2010@1|root,COG2010@2|Bacteria,1RH1S@1224|Proteobacteria,1S42K@1236|Gammaproteobacteria,1XS7Y@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_15206_3 1278309.KB907101_gene474 1.09e-182 512.0 COG0834@1|root,COG0834@2|Bacteria,1RIGN@1224|Proteobacteria,1RR7F@1236|Gammaproteobacteria,1XHYV@135619|Oceanospirillales 135619|Oceanospirillales ET Bacterial extracellular solute-binding proteins, family 3 - - - - - - - - - - - - SBP_bac_3 k141_15206_5 1278309.KB907101_gene478 0.0 973.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1XH89@135619|Oceanospirillales 135619|Oceanospirillales G Dehydrogenase - - - - - - - - - - - - PQQ k141_16677_1 1120963.KB894499_gene440 1.86e-07 53.5 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,2PZGA@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_16677_2 349124.Hhal_0485 1.19e-17 81.6 COG3190@1|root,COG3190@2|Bacteria,1PQ37@1224|Proteobacteria,1TK5Y@1236|Gammaproteobacteria,1WZNW@135613|Chromatiales 135613|Chromatiales N PFAM flagellar biosynthesis protein, FliO - - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_16677_3 95619.PM1_0219480 5.35e-48 159.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria 1236|Gammaproteobacteria N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C,FliN_N k141_16677_4 349124.Hhal_0487 3.15e-114 340.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1WWMX@135613|Chromatiales 135613|Chromatiales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_6223_1 1123253.AUBD01000004_gene1062 1.27e-35 136.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1X5V3@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_659_1 396588.Tgr7_1499 7.93e-46 167.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF k141_659_2 1502770.JQMG01000001_gene243 3.21e-21 91.3 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,2KMNB@206350|Nitrosomonadales 206350|Nitrosomonadales S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_7626_1 1278309.KB907099_gene2812 3.99e-68 214.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XHIK@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_7626_2 1278309.KB907099_gene2811 8.92e-109 316.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1T28J@1236|Gammaproteobacteria,1XS7V@135619|Oceanospirillales 135619|Oceanospirillales S Flavodoxin domain - - - - - - - - - - - - FMN_red k141_7626_3 1278309.KB907099_gene2808 2.12e-72 219.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,1XKRU@135619|Oceanospirillales 135619|Oceanospirillales I hydrolase - - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT k141_7626_4 1278309.KB907099_gene2807 3.15e-101 296.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria,1XK6N@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_7626_5 1278309.KB907099_gene2805 7.65e-91 270.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,1XKK5@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09912 - - - - ko00000 - - - DUF2058 k141_2028_1 1168067.JAGP01000001_gene1737 7.23e-96 307.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales 72273|Thiotrichales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_17366_1 1278309.KB907110_gene3190 1.11e-117 353.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1XHUX@135619|Oceanospirillales 135619|Oceanospirillales T PrkA family serine protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_8987_1 999611.KI421504_gene188 1.18e-13 70.9 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,280F4@191028|Leisingera 28211|Alphaproteobacteria V AAA domain, putative AbiEii toxin, Type IV TA system hndI GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_8987_2 998674.ATTE01000001_gene4108 1.59e-137 394.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,461WB@72273|Thiotrichales 72273|Thiotrichales U Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_2736_1 1123499.KB908023_gene1215 2.55e-16 75.9 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,2KQQE@206351|Neisseriales 206351|Neisseriales M Transglycosylase SLT domain protein - - - - - - - - - - - - SLT k141_2736_2 511145.b0968 1.24e-19 82.8 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,3XPZE@561|Escherichia 1236|Gammaproteobacteria C acylphosphatase activity acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Acylphosphatase k141_7670_2 1232683.ADIMK_3075 3.23e-14 71.2 COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,464R9@72275|Alteromonadaceae 1236|Gammaproteobacteria C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters nifU - - ko:K04488,ko:K13819 - - - - ko00000 - - - Fer2_BFD,NifU,NifU_N k141_20910_1 1278309.KB907103_gene1023 8.36e-297 845.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XIKY@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_20910_2 1278309.KB907103_gene1024 0.0 892.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XHB0@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,AAA_30,UvrD_C_2 k141_20910_3 1278309.KB907103_gene1025 3.07e-51 162.0 COG0695@1|root,COG0695@2|Bacteria,1RGZ7@1224|Proteobacteria,1S5ZP@1236|Gammaproteobacteria,1XM7R@135619|Oceanospirillales 135619|Oceanospirillales O Glutaredoxin grxA - - ko:K03674 - - - - ko00000,ko03110 - - - Glutaredoxin k141_20910_4 1278309.KB907103_gene1026 2.55e-91 268.0 COG0664@1|root,COG0664@2|Bacteria,1N6GM@1224|Proteobacteria,1SGRK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_16731_1 1123368.AUIS01000011_gene1183 1.38e-24 95.9 COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_19519_1 472759.Nhal_3897 1.84e-79 252.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales 135613|Chromatiales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_6971_1 1437824.BN940_11651 8.86e-05 43.5 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,3T2Q6@506|Alcaligenaceae 28216|Betaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_6971_2 870187.Thini_3419 8.66e-63 198.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,461BG@72273|Thiotrichales 72273|Thiotrichales J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_6971_3 1279017.AQYJ01000026_gene325 2.26e-35 123.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,467U2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_6971_4 400668.Mmwyl1_3771 4.73e-99 302.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1XIPR@135619|Oceanospirillales 135619|Oceanospirillales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_14640_1 743720.Psefu_3732 2.97e-83 281.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YWZV@136845|Pseudomonas putida group 1236|Gammaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) morA - - - - - - - - - - - EAL,GGDEF,PAS,PAS_8,PAS_9,dCache_2 k141_2_1 573.JG24_06430 4.18e-07 50.4 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM PEBP family protein ybhB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06910 - - - - ko00000 - - - PBP k141_2_2 485918.Cpin_5439 1.51e-67 208.0 COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia 976|Bacteroidetes C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_698_2 674977.VMC_17160 1.13e-94 287.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XSUQ@135623|Vibrionales 135623|Vibrionales H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 ygdL - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_698_3 768671.ThimaDRAFT_3963 1.83e-107 318.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1WWHE@135613|Chromatiales 135613|Chromatiales L hydrolase, TatD family - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_698_6 1116472.MGMO_54c00050 5.9e-16 77.4 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1XENB@135618|Methylococcales 135618|Methylococcales S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC k141_12548_1 913325.N799_05845 2.22e-63 214.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1X2XH@135614|Xanthomonadales 135614|Xanthomonadales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_18822_1 1168065.DOK_16778 0.000462 44.7 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1J4RD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_10458_1 290398.Csal_1675 2.2e-41 150.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,1XIHF@135619|Oceanospirillales 135619|Oceanospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_4881_1 225937.HP15_778 2.97e-64 200.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,468GR@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3086 Positive regulator of sigma E activity rseC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_2789_1 1278309.KB907100_gene2051 6.89e-210 585.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XI42@135619|Oceanospirillales 135619|Oceanospirillales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_20911_1 1288826.MSNKSG1_04711 9.23e-62 189.0 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,1SFHW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 k141_13942_1 279714.FuraDRAFT_1984 1.22e-89 278.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KQM4@206351|Neisseriales 206351|Neisseriales L Belongs to the DEAD box helicase family dbpA - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_8368_1 935848.JAEN01000004_gene1430 1.69e-48 166.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,2PUKF@265|Paracoccus 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e k141_1398_1 693986.MOC_5191 5e-118 345.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,1JTBT@119045|Methylobacteriaceae 28211|Alphaproteobacteria I NADP oxidoreductase coenzyme F420-dependent MA20_25935 - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_1398_2 1185766.DL1_00155 0.000854 42.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2XKJS@285107|Thioclava 28211|Alphaproteobacteria S Penicillin amidase quiP - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_7671_1 637389.Acaty_c1087 6.34e-05 46.6 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,2NCYF@225057|Acidithiobacillales 225057|Acidithiobacillales M Penicillin-Binding Protein C-terminus Family - - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase k141_7671_2 1208583.COMX_07970 2.19e-34 136.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,2JPP9@204441|Rhodospirillales 204441|Rhodospirillales S Alpha-2-Macroglobulin - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl k141_4184_1 751994.AGIG01000027_gene1496 2.72e-27 103.0 COG1476@1|root,COG1476@2|Bacteria,1N2TN@1224|Proteobacteria,1S98W@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix - - - - - - - - - - - - HTH_3 k141_4184_2 565045.NOR51B_344 2.22e-168 483.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RRUJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Divalent cation transporter - - - - - - - - - - - - CBS,MgtE k141_4184_3 1278309.KB907099_gene2367 8.87e-215 593.0 COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,1RPH7@1236|Gammaproteobacteria,1XI23@135619|Oceanospirillales 135619|Oceanospirillales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.15 ko:K00455 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R03303 RC00643 ko00000,ko00001,ko00002,ko01000 - - - LigB k141_4184_4 207954.MED92_10589 3.69e-235 669.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,1XHXT@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_4184_5 1122201.AUAZ01000023_gene3024 8.94e-81 242.0 2DMP1@1|root,32SS8@2|Bacteria,1N0XZ@1224|Proteobacteria,1S9MX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0311 family - - - - - - - - - - - - DUF3237 k141_6275_1 1288826.MSNKSG1_09623 2.2e-139 409.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_17426_1 396588.Tgr7_2136 3.42e-24 94.4 COG4831@1|root,COG4831@2|Bacteria,1NMBS@1224|Proteobacteria,1SHJI@1236|Gammaproteobacteria,1X1V5@135613|Chromatiales 135613|Chromatiales S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_7672_1 2055.JNXA01000026_gene4107 7.39e-45 160.0 COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4GCJ8@85026|Gordoniaceae 201174|Actinobacteria S Sulfatase-modifying factor enzyme 1 egtB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - DinB_2,FGE-sulfatase k141_13943_1 1519464.HY22_13050 1.68e-53 184.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process yjcH - - ko:K07214 - - - - ko00000 - - - Esterase k141_13247_1 1238450.VIBNISOn1_1530069 1.25e-41 156.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XV3Y@135623|Vibrionales 135623|Vibrionales NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,PAS_8,PAS_9 k141_9063_1 1278309.KB907116_gene3313 9.35e-17 89.7 COG3210@1|root,COG3210@2|Bacteria,1NE9M@1224|Proteobacteria 1224|Proteobacteria U pathogenesis - - - - - - - - - - - - PATR k141_20913_1 1278309.KB907099_gene2596 4.86e-90 268.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1S0IN@1236|Gammaproteobacteria,1XR8I@135619|Oceanospirillales 135619|Oceanospirillales T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_15337_1 935567.JAES01000051_gene321 1.23e-12 68.6 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1X52S@135614|Xanthomonadales 135614|Xanthomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_15337_2 754477.Q7C_2097 2.32e-40 143.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,4617Y@72273|Thiotrichales 72273|Thiotrichales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB k141_11157_1 713587.THITH_09725 2.24e-34 125.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_14642_1 1117647.M5M_04980 4.19e-84 275.0 COG0515@1|root,COG3118@1|root,COG0515@2|Bacteria,COG3118@2|Bacteria,1QVRP@1224|Proteobacteria,1T2I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K11912,ko:K12132 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - Pkinase k141_19521_1 1230338.MOMA_05205 1.81e-33 127.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3NK1I@468|Moraxellaceae 1236|Gammaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - iPC815.YPO3376 Enolase_C,Enolase_N k141_19521_2 105559.Nwat_2256 7.17e-83 252.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1WWZU@135613|Chromatiales 135613|Chromatiales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_4882_1 1232683.ADIMK_3122 9.34e-29 115.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_4882_2 616991.JPOO01000003_gene1762 7.22e-46 152.0 COG0346@1|root,COG0346@2|Bacteria,4NT9B@976|Bacteroidetes,1I9Z9@117743|Flavobacteriia 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_7673_1 1049564.TevJSym_ad01330 5e-86 267.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1J4V5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_16732_1 1232683.ADIMK_1409 6.2e-276 758.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,466T8@72275|Alteromonadaceae 1236|Gammaproteobacteria E FMN-dependent dehydrogenase - - 1.4.1.13,1.4.1.14,2.1.1.21 ko:K00265,ko:K22083 ko00250,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00680,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248,R01586 RC00006,RC00010,RC00554,RC02799 ko00000,ko00001,ko01000 - - - Glu_synthase k141_13248_2 1121943.KB899989_gene3178 4.19e-62 202.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1XH7N@135619|Oceanospirillales 135619|Oceanospirillales S Transcription factor - - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_14643_1 472759.Nhal_2686 5.21e-67 212.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales 135613|Chromatiales H Belongs to the NadC ModD family - - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_6276_1 1049564.TevJSym_ac01310 1.07e-98 303.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1J5IR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_13944_1 317025.Tcr_0389 5.29e-15 73.9 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales 72273|Thiotrichales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_13944_2 498211.CJA_0651 7.32e-59 197.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1FGG5@10|Cellvibrio 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_2096_1 870187.Thini_4133 5.21e-111 336.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,461SS@72273|Thiotrichales 72273|Thiotrichales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_2096_2 1279015.KB908457_gene2270 6.6e-96 291.0 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,1Y3SK@135624|Aeromonadales 135624|Aeromonadales I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_13249_1 187272.Mlg_1950 3.09e-09 56.6 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1WY8Z@135613|Chromatiales 135613|Chromatiales S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_699_1 1242864.D187_010025 2.17e-58 192.0 COG0693@1|root,COG0693@2|Bacteria,1MYPJ@1224|Proteobacteria,42RVZ@68525|delta/epsilon subdivisions,2X5WP@28221|Deltaproteobacteria,2YYGJ@29|Myxococcales 28221|Deltaproteobacteria S DJ-1/PfpI family - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_11853_1 493475.GARC_2203 4.86e-87 273.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19523_1 1268237.G114_06917 1.01e-23 100.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1Y3TV@135624|Aeromonadales 135624|Aeromonadales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_7675_1 413404.Rmag_0859 4.08e-29 114.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1SMKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_7675_2 713587.THITH_12030 5.62e-51 167.0 COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria,1WVZM@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11,Fer4_7 k141_9064_1 1123073.KB899241_gene2359 2.45e-155 456.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_1399_1 642227.HA49_19155 1.82e-19 87.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,4BUP7@82986|Tatumella 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_1399_2 1335757.SPICUR_07680 2.3e-69 213.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1WYVR@135613|Chromatiales 135613|Chromatiales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ k141_15338_1 1116472.MGMO_152c00040 6.94e-86 270.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XEKR@135618|Methylococcales 135618|Methylococcales F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_18825_1 580332.Slit_0902 1.15e-60 200.0 2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,2VM8Z@28216|Betaproteobacteria,44WDX@713636|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_7676_1 1122137.AQXF01000007_gene3495 1.39e-60 208.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,2U1KH@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21609_1 207954.MED92_02651 1.22e-77 237.0 COG1309@1|root,COG1309@2|Bacteria,1NM93@1224|Proteobacteria,1S56I@1236|Gammaproteobacteria,1XP5A@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_14644_1 935567.JAES01000034_gene1741 6.6e-17 79.3 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1X3M7@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_14644_2 1449050.JNLE01000003_gene2666 1.22e-15 74.3 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,36JHM@31979|Clostridiaceae 186801|Clostridia P Belongs to the ArsC family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin k141_11164_1 1454004.AW11_02845 5.39e-78 248.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2VPFR@28216|Betaproteobacteria 28216|Betaproteobacteria P Citrate transporter - - - - - - - - - - - - CitMHS k141_4188_1 396588.Tgr7_1990 8.82e-72 243.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg k141_11860_2 317025.Tcr_0182 2.39e-16 77.8 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,45ZYE@72273|Thiotrichales 72273|Thiotrichales D Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_12557_1 1163617.SCD_n02038 3.25e-36 134.0 COG0191@1|root,COG0191@2|Bacteria,1R6TC@1224|Proteobacteria,2VMUH@28216|Betaproteobacteria 28216|Betaproteobacteria G ketose-bisphosphate aldolase - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k141_9765_1 1173025.GEI7407_0433 3.56e-06 56.6 COG3209@1|root,COG3210@1|root,COG3240@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3240@2|Bacteria 2|Bacteria I lipase activity - - - ko:K15125 ko05133,map05133 - - - ko00000,ko00001,ko00536 - - - CHU_C,Calx-beta,Lipase_GDSL,RHS_repeat k141_844_3 1158146.KB907122_gene448 1.04e-66 216.0 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RRA7@1236|Gammaproteobacteria,1WX03@135613|Chromatiales 135613|Chromatiales S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k141_11326_1 1049564.TevJSym_bc00240 1.33e-70 234.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1J5PE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_16156_1 1026882.MAMP_00334 1.48e-123 387.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales 72273|Thiotrichales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_14798_1 400668.Mmwyl1_2684 8.6e-68 216.0 COG2358@1|root,COG2358@2|Bacteria,1N3WH@1224|Proteobacteria,1SP12@1236|Gammaproteobacteria,1XPNB@135619|Oceanospirillales 135619|Oceanospirillales S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_3635_1 768671.ThimaDRAFT_4026 3.14e-50 160.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales 135613|Chromatiales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_2224_1 395493.BegalDRAFT_3361 3.08e-157 448.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,4600A@72273|Thiotrichales 72273|Thiotrichales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_110_1 1288826.MSNKSG1_15107 6.32e-165 478.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_14088_1 2340.JV46_27210 6.83e-115 348.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7AF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F 5'-nucleotidase, C-terminal domain soxB - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C k141_9183_1 1318628.MARLIPOL_02250 5.81e-174 499.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae 1236|Gammaproteobacteria P alkaline phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_10615_3 879212.DespoDRAFT_00492 7.59e-13 68.6 28IZT@1|root,2Z8X3@2|Bacteria,1R4RF@1224|Proteobacteria,42QV2@68525|delta/epsilon subdivisions,2WMYU@28221|Deltaproteobacteria,2MJR5@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_13400_1 391038.Bphy_0796 1.6e-45 166.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae 28216|Betaproteobacteria I Phospholipase D Transphosphatidylase - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_12691_1 1120983.KB894578_gene3714 0.000188 45.1 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,1JN7Z@119043|Rhodobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain gst7 - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_N,GST_N_3 k141_20392_1 1163408.UU9_01899 2.7e-95 303.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1X2YZ@135614|Xanthomonadales 135614|Xanthomonadales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_7114_1 1288826.MSNKSG1_06118 7.26e-09 55.5 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,4642Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_7114_2 1288826.MSNKSG1_06123 3e-96 287.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RN0N@1236|Gammaproteobacteria,4663H@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 cioB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_18974_1 1288826.MSNKSG1_09753 2.65e-21 90.9 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,4648M@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_18974_2 1288826.MSNKSG1_09758 0.0 875.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,465HT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0733 Na -dependent transporters of the SNF family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_18974_3 1288826.MSNKSG1_09763 6.48e-205 566.0 COG3687@1|root,COG3687@2|Bacteria,1MWGV@1224|Proteobacteria,1SKSI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metal-dependent hydrolase - - - ko:K07044 - - - - ko00000 - - - Metal_hydrol k141_18974_4 1288826.MSNKSG1_09768 4.62e-222 611.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,464ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0846 NAD-dependent protein deacetylases, SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_18974_5 1288826.MSNKSG1_09773 5.88e-166 465.0 COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,1T268@1236|Gammaproteobacteria,466KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0421 Spermidine synthase - - - - - - - - - - - - - k141_15515_1 765869.BDW_04435 6.82e-13 70.1 COG4968@1|root,COG4968@2|Bacteria,1QXV9@1224|Proteobacteria,42VR9@68525|delta/epsilon subdivisions,2MT99@213481|Bdellovibrionales,2WRJV@28221|Deltaproteobacteria 213481|Bdellovibrionales NU Pfam:N_methyl_2 pilA GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin_PilA k141_15515_2 323261.Noc_0312 1.47e-06 50.1 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_2932_1 305900.GV64_20525 3.29e-61 191.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1XJHH@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_16157_1 89187.ISM_04295 3.68e-108 320.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,2TS8Y@28211|Alphaproteobacteria,46RIK@74030|Roseovarius 28211|Alphaproteobacteria P COG4175 ABC-type proline glycine betaine transport system, ATPase component - - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran k141_16876_1 349521.HCH_02590 2.95e-65 209.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XNPS@135619|Oceanospirillales 135619|Oceanospirillales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_5749_1 323261.Noc_0812 2.26e-54 177.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1WX0N@135613|Chromatiales 135613|Chromatiales I Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_1530_1 1288826.MSNKSG1_18245 3.7e-108 315.0 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1S9Y3@1236|Gammaproteobacteria,467S5@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG3087 Cell division protein - - - ko:K03591 - - - - ko00000,ko03036 - - - SPOR k141_2225_1 1122137.AQXF01000008_gene3441 5.66e-46 161.0 2DPNR@1|root,332SN@2|Bacteria,1Q8EA@1224|Proteobacteria,2UT54@28211|Alphaproteobacteria 2|Bacteria - - - - - - - - - - - - - - - k141_12005_1 1288826.MSNKSG1_10163 2.04e-65 199.0 2AMAC@1|root,31C5B@2|Bacteria,1RI20@1224|Proteobacteria,1S9JQ@1236|Gammaproteobacteria,468S8@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_12005_2 1288826.MSNKSG1_10168 4.77e-162 455.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_17559_1 2340.JV46_13280 1.23e-59 187.0 2E1WQ@1|root,32X5W@2|Bacteria,1N2F8@1224|Proteobacteria,1SA2N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17559_2 396588.Tgr7_3073 5.12e-117 349.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales 135613|Chromatiales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_8506_1 517417.Cpar_2036 1.77e-68 221.0 COG0531@1|root,COG0531@2|Bacteria,1FESF@1090|Chlorobi 1090|Chlorobi E PFAM amino acid permease-associated region - - - - - - - - - - - - AA_permease_2 k141_8506_2 1163408.UU9_05434 2.96e-16 75.5 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,1S2I3@1236|Gammaproteobacteria,1X6BV@135614|Xanthomonadales 135614|Xanthomonadales S integral membrane protein - - - - - - - - - - - - DUF1211 k141_9876_1 195250.CM001776_gene2503 5.14e-08 57.8 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1G31U@1117|Cyanobacteria,1H1U9@1129|Synechococcus 1117|Cyanobacteria T GAF domain - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA_3,PAS_9 k141_15538_2 1288826.MSNKSG1_03931 1.39e-158 445.0 COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,46AMF@72275|Alteromonadaceae 1236|Gammaproteobacteria E Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - HAD_2,Hydrolase k141_15538_3 1288826.MSNKSG1_03926 3.14e-136 385.0 COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,46AN1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_00643 ARD k141_15538_4 1288826.MSNKSG1_03921 3.57e-156 438.0 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,46974@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.1.1.104,4.2.1.109 ko:K08964,ko:K22130 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_15538_5 1288826.MSNKSG1_03916 1.67e-39 139.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria,466FW@72275|Alteromonadaceae 1236|Gammaproteobacteria O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family yagQ - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_21741_1 1278309.KB907107_gene1657 2.72e-135 393.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1XHAW@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_13416_1 1288826.MSNKSG1_06943 0.0 974.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,469ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k141_13416_2 1288826.MSNKSG1_06938 2.92e-228 630.0 COG5653@1|root,COG5653@2|Bacteria,1RINE@1224|Proteobacteria,1S23E@1236|Gammaproteobacteria,467IB@72275|Alteromonadaceae 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_13416_3 1288826.MSNKSG1_06933 3.32e-243 670.0 COG5653@1|root,COG5653@2|Bacteria,1QUMR@1224|Proteobacteria,1RN5W@1236|Gammaproteobacteria,464GN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6,Seryl_tRNA_N k141_13416_4 1288826.MSNKSG1_06928 9.75e-126 367.0 COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria,465P7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis gt2M - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_16886_1 765913.ThidrDRAFT_0792 2.72e-28 113.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_14815_1 1278309.KB907103_gene1044 4.3e-115 354.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XISF@135619|Oceanospirillales 135619|Oceanospirillales M Sterol-sensing domain of SREBP cleavage-activation - - - ko:K07003 - - - - ko00000 - - - MMPL k141_857_1 880072.Desac_0330 4.88e-79 255.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales 28221|Deltaproteobacteria K two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21742_1 225937.HP15_1240 4.72e-14 66.6 COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria,467S4@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K11022 ko05134,map05134 - - - ko00000,ko00001,ko02042 - - - - k141_21742_2 396588.Tgr7_1108 1.09e-45 151.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1S73Y@1236|Gammaproteobacteria,1X24K@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_16887_1 402612.FP0293 2.19e-71 222.0 COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia,2NSSP@237|Flavobacterium 976|Bacteroidetes G polysaccharide deacetylase pgdA_1 - - - - - - - - - - - Polysacc_deac_1 k141_11356_1 351348.Maqu_3344 8.2e-83 265.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4651T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_14816_2 1288826.MSNKSG1_08113 1.87e-77 239.0 2ECVF@1|root,336ST@2|Bacteria,1NZ5X@1224|Proteobacteria,1SQ0V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1551_2 243233.MCA0540 8.51e-58 190.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1S5KU@1236|Gammaproteobacteria,1XDYF@135618|Methylococcales 135618|Methylococcales GM NAD(P)H-binding - - - - - - - - - - - - Epimerase k141_12012_1 371731.Rsw2DRAFT_1711 7.06e-29 119.0 COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,2TTAJ@28211|Alphaproteobacteria,1FCDJ@1060|Rhodobacter 28211|Alphaproteobacteria M Capsule polysaccharide biosynthesis protein kpsC - - ko:K07266 - - - - ko00000 - - - Capsule_synth k141_5766_1 713586.KB900536_gene1873 5.22e-13 64.3 COG5481@1|root,COG5481@2|Bacteria,1QB94@1224|Proteobacteria,1SHNI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 k141_9190_1 1123355.JHYO01000031_gene1600 3.67e-10 60.5 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,36Y4X@31993|Methylocystaceae 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_9190_2 1278309.KB907101_gene351 7.18e-205 571.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RPA8@1236|Gammaproteobacteria,1XI8Q@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_9190_3 1278309.KB907101_gene352 3.22e-83 249.0 COG3090@1|root,COG3090@2|Bacteria,1MYII@1224|Proteobacteria,1S73D@1236|Gammaproteobacteria,1XR2Q@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_9190_4 1123228.AUIH01000031_gene1684 3.56e-18 83.2 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,1XIET@135619|Oceanospirillales 135619|Oceanospirillales G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM k141_2231_1 1042375.AFPL01000012_gene711 2.05e-216 606.0 COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,468Z1@72275|Alteromonadaceae 1236|Gammaproteobacteria C Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_2231_2 1042375.AFPL01000012_gene710 3.18e-265 759.0 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,46AS5@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporter VP0886 - - - - - - - - - - - MMPL k141_2231_3 1042375.AFPL01000012_gene709 1.57e-51 169.0 COG2834@1|root,COG2834@2|Bacteria,1N9W4@1224|Proteobacteria,1SCRF@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - LolA k141_2231_4 491952.Mar181_0553 1.92e-60 189.0 COG0824@1|root,COG0824@2|Bacteria,1RH6W@1224|Proteobacteria,1S6BU@1236|Gammaproteobacteria,1XPS6@135619|Oceanospirillales 135619|Oceanospirillales S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_2231_5 1042375.AFPL01000012_gene707 7.65e-153 438.0 COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,1RNKV@1236|Gammaproteobacteria,46AHT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acyltransferase ycdQ - - - - - - - - - - - Glycos_transf_2,Lip_A_acyltrans k141_2231_6 1500897.JQNA01000001_gene6440 2.75e-84 270.0 COG1216@1|root,COG4261@1|root,COG1216@2|Bacteria,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2WH20@28216|Betaproteobacteria,1KIGT@119060|Burkholderiaceae 28216|Betaproteobacteria S Pfam Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,Lip_A_acyltrans k141_2231_7 1123355.JHYO01000009_gene3103 6.97e-10 60.5 COG0764@1|root,COG0764@2|Bacteria,1NAA7@1224|Proteobacteria,2UNK2@28211|Alphaproteobacteria 28211|Alphaproteobacteria I 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) - - - - - - - - - - - - FabA k141_9887_1 1288826.MSNKSG1_04186 0.0 1145.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_5009_1 1278309.KB907102_gene239 1.09e-155 443.0 COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria,1XIEH@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.21 ko:K06182 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_5009_2 1265503.KB905166_gene888 5.8e-132 380.0 COG1414@1|root,COG1414@2|Bacteria,1R5ZB@1224|Proteobacteria,1RY6E@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR k141_5009_4 1122599.AUGR01000007_gene1135 3.18e-315 863.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XIE7@135619|Oceanospirillales 135619|Oceanospirillales C methylmalonate-semialdehyde dehydrogenase - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_5009_5 1121940.AUDZ01000013_gene676 1.07e-87 268.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XP0U@135619|Oceanospirillales 135619|Oceanospirillales C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_17583_1 857087.Metme_3732 1.71e-130 389.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XENA@135618|Methylococcales 135618|Methylococcales KLT kinase domain - - - - - - - - - - - - PP2C_2,Pkinase k141_17583_2 870187.Thini_2789 1.63e-55 185.0 COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales 72273|Thiotrichales S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_17583_3 754476.Q7A_2630 2.33e-13 68.6 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,462W0@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_21743_1 1121918.ARWE01000001_gene3561 5.11e-133 384.0 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,42RTY@68525|delta/epsilon subdivisions,2WNFS@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_19680_1 1278309.KB907099_gene2613 1.07e-102 327.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,1XI5X@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG - 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_19680_2 1278309.KB907099_gene2633 0.0 959.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1XHV1@135619|Oceanospirillales 135619|Oceanospirillales P nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_19680_3 1278309.KB907099_gene2632 8.51e-170 483.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1XI0Y@135619|Oceanospirillales 135619|Oceanospirillales P Major Facilitator Superfamily - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_16172_1 1288826.MSNKSG1_07383 0.0 1207.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,464M6@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_16172_3 1288826.MSNKSG1_07373 2.83e-180 500.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,465QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_16172_4 1288826.MSNKSG1_07368 3.87e-178 495.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,466EF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans k141_16172_5 1288826.MSNKSG1_07363 4.64e-226 623.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,465FC@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - iPC815.YPO1374 Pyr_redox_2 k141_16172_6 1288826.MSNKSG1_07358 3.2e-210 582.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,464EU@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_16172_7 1288826.MSNKSG1_07353 1.94e-216 597.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,465G5@72275|Alteromonadaceae 1236|Gammaproteobacteria S amidohydrolase aguB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_8032_3 1278309.KB907111_gene3387 3.88e-243 670.0 COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,1RQY8@1236|Gammaproteobacteria,1XIRU@135619|Oceanospirillales 135619|Oceanospirillales S COG1994 Zn-dependent proteases - - - - - - - - - - - - - k141_8032_4 1123504.JQKD01000059_gene2935 2.57e-64 207.0 COG0745@1|root,COG0745@2|Bacteria,1MWER@1224|Proteobacteria,2VN6D@28216|Betaproteobacteria,4AGFB@80864|Comamonadaceae 28216|Betaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_8032_5 1278309.KB907099_gene2574 8.32e-112 356.0 COG4564@1|root,COG5000@1|root,COG4564@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1T35N@1236|Gammaproteobacteria,1XRT7@135619|Oceanospirillales 135619|Oceanospirillales T Cache_2 - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2 k141_16308_2 754477.Q7C_1743 1.44e-51 164.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,460WX@72273|Thiotrichales 72273|Thiotrichales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_12879_1 1288826.MSNKSG1_17446 1.26e-120 349.0 2DQIT@1|root,33749@2|Bacteria,1N9CN@1224|Proteobacteria,1ST3J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP k141_1731_1 765913.ThidrDRAFT_0189 3.26e-113 338.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_17764_1 1122212.AULO01000007_gene2272 7.03e-46 162.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_17764_2 95619.PM1_0206455 1.73e-56 184.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-binding protein ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - - - - - - - - - - NIF3 k141_18425_1 1198452.Jab_1c24210 9.35e-36 149.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472C3@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_9,Response_reg k141_11472_2 130081.XP_005705097.1 1.13e-09 60.8 COG0080@1|root,KOG3257@2759|Eukaryota 2759|Eukaryota J rRNA binding MRPL11 GO:0000027,GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006414,GO:0006415,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0019866,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032984,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070125,GO:0070126,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867,ko:K03260 ko03010,ko03013,ko05416,map03010,map03013,map05416 M00178,M00179,M00428 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03012,ko03019 - - - Ribosomal_L11,Ribosomal_L11_N k141_12172_1 261292.Nit79A3_0120 8.49e-09 57.4 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria,373TZ@32003|Nitrosomonadales 28216|Betaproteobacteria T HDOD domain - - - - - - - - - - - - EAL,HDOD k141_12172_2 1286170.RORB6_19365 3.84e-26 96.7 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k141_12172_3 876044.IMCC3088_2193 3.56e-41 136.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1J6PJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k141_3136_1 1232683.ADIMK_0999 4.77e-22 94.4 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,4643F@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_3136_2 379731.PST_3643 8.86e-42 150.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1Z084@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_21266_2 1423321.AS29_21125 2.6e-20 94.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309,ko:K11102 - - - - ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 - iYO844.BSU10220 SDF k141_8666_1 522306.CAP2UW1_2225 4.76e-79 238.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria,1KQZR@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_21938_1 396588.Tgr7_0365 9.3e-59 183.0 COG2920@1|root,COG2920@2|Bacteria 2|Bacteria P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_21938_2 713587.THITH_03795 2.75e-57 185.0 2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,1SJ45@1236|Gammaproteobacteria,1X0T7@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_6539_1 715451.ambt_17470 0.00064 40.0 COG5567@1|root,COG5567@2|Bacteria 2|Bacteria N small periplasmic lipoprotein yifL - - - - - - - - - - - LPAM_2 k141_6539_2 264730.PSPPH_5010 7.06e-26 100.0 COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,1Z7QT@136849|Pseudomonas syringae group 1236|Gammaproteobacteria P Belongs to the frataxin family cyaY GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 - ko:K06202 - - - - ko00000 - - iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108 Frataxin_Cyay k141_6539_3 1278309.KB907100_gene2080 1.15e-80 242.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XKC8@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_1002_1 1288826.MSNKSG1_16906 1.04e-297 813.0 COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,465D3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Splits dipeptides with a prolyl residue in the C- terminal position pepQ GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_1002_2 1288826.MSNKSG1_16911 1.83e-43 141.0 COG2906@1|root,COG2906@2|Bacteria,1NGGY@1224|Proteobacteria,1SGGM@1236|Gammaproteobacteria,4690S@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2906 Bacterioferritin-associated ferredoxin bfd - - ko:K02192 - - - - ko00000 - - - Fer2_BFD k141_1002_3 1288826.MSNKSG1_16916 3.81e-103 299.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,1S45S@1236|Gammaproteobacteria,466EC@72275|Alteromonadaceae 1236|Gammaproteobacteria P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_1002_4 1288826.MSNKSG1_16921 0.0 908.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,4645I@72275|Alteromonadaceae 1236|Gammaproteobacteria G phosphomannomutase manB - 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_8033_1 596154.Alide2_0697 7.18e-28 118.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria,4ACXB@80864|Comamonadaceae 28216|Betaproteobacteria C Protein of unknown function (DUF3485) epsH - - - - - - - - - - - DUF3485,Exosortase_EpsH k141_7282_1 1122599.AUGR01000014_gene554 0.0 1152.0 COG0747@1|root,COG0747@2|Bacteria,1N4PK@1224|Proteobacteria,1RZPY@1236|Gammaproteobacteria,1XMES@135619|Oceanospirillales 135619|Oceanospirillales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_7282_2 1122599.AUGR01000014_gene553 9.97e-230 639.0 COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,1RSBZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_7282_3 1122599.AUGR01000014_gene552 1.78e-256 708.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XH9S@135619|Oceanospirillales 135619|Oceanospirillales EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N k141_7282_4 357804.Ping_3157 5.26e-161 468.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K13896,ko:K19229,ko:K19230 ko01503,ko02010,ko02024,map01503,map02010,map02024 M00239,M00349,M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24,3.A.1.5.5 - - ABC_tran,oligo_HPY k141_10033_1 999141.GME_10081 1.8e-160 477.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales 135619|Oceanospirillales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_10033_2 105559.Nwat_2770 3.2e-85 285.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXR1@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,dCache_3 k141_14937_1 1288826.MSNKSG1_06973 4.5e-107 321.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,464MI@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2148 Sugar transferases involved in lipopolysaccharide synthesis lthA - - - - - - - - - - - Bac_transf,CoA_binding_3 k141_14937_2 1288826.MSNKSG1_06978 7.46e-231 635.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae 1236|Gammaproteobacteria G xylanase chitin deacetylase - - - - - - - - - - - - DUF3473,Polysacc_deac_1 k141_14937_3 1288826.MSNKSG1_06983 7.02e-212 588.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretory pathway component ExeA - - - - - - - - - - - - AAA_22,OmpA k141_11473_1 2340.JV46_26980 5.61e-12 67.0 COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria,1J68K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M membrane - - - - - - - - - - - - Porin_4 k141_3137_1 1002339.HMPREF9373_0958 2.44e-38 146.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,3NJ4F@468|Moraxellaceae 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k141_19169_1 485917.Phep_0868 7.51e-08 56.6 COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1IRJS@117747|Sphingobacteriia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_19169_2 454957.IA64_04055 4.61e-28 113.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1X580@135614|Xanthomonadales 135614|Xanthomonadales S ATPase (AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_17765_1 519989.ECTPHS_07242 6.84e-143 419.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales 135613|Chromatiales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_4517_1 1208321.D104_17815 1.81e-31 119.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XHYW@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_5895_1 765912.Thimo_0822 5.22e-90 284.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_8667_1 28229.ND2E_0802 4.78e-44 146.0 2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,2Q73G@267889|Colwelliaceae 1236|Gammaproteobacteria S HopJ type III effector protein hopJ - - - - - - - - - - - HopJ k141_8667_2 1278309.KB907099_gene3048 3.17e-17 79.3 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_19810_1 1353537.TP2_13465 1.53e-11 63.9 2DNYF@1|root,32ZSU@2|Bacteria,1N8ZB@1224|Proteobacteria,2UK7W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S HupH hydrogenase expression protein, C-terminal conserved region - - - - - - - - - - - - HupH_C k141_19810_2 1049564.TevJSym_bc00360 2.65e-179 508.0 COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NiFe/NiFeSe hydrogenase small subunit C-terminal - - 1.12.99.6 ko:K06282 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFe_hyd_SSU_C,Oxidored_q6 k141_8034_1 768671.ThimaDRAFT_3035 9.63e-45 159.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WX7A@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_8034_2 227377.CBU_1875 3.21e-26 104.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1JD4I@118969|Legionellales 118969|Legionellales H Prokaryotic glutathione synthetase, N-terminal domain gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_6540_1 323850.Shew_0800 1.06e-51 180.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,2QAJ6@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM FAD dependent oxidoreductase eryB - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO k141_21267_1 1288826.MSNKSG1_11273 1.87e-122 349.0 COG3018@1|root,COG3018@2|Bacteria,1N3JR@1224|Proteobacteria,1S9MW@1236|Gammaproteobacteria,46CD1@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09860 - - - - ko00000 - - - LPP20 k141_7284_1 243233.MCA1533 1.46e-12 75.5 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GGDEF k141_17766_1 411684.HPDFL43_02475 1.22e-110 330.0 COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2TR9B@28211|Alphaproteobacteria,43GUA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family xylH GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10544 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - BPD_transp_2 k141_17766_2 411684.HPDFL43_02480 2.47e-26 103.0 COG1129@1|root,COG1129@2|Bacteria,1P3ZB@1224|Proteobacteria,2VET1@28211|Alphaproteobacteria,43I52@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G ABC transporter xylG - 3.6.3.17 ko:K10545 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.4 - - ABC_tran k141_1003_1 290400.Jann_4033 4.37e-26 100.0 COG4333@1|root,COG4333@2|Bacteria,1N19M@1224|Proteobacteria,2U5K3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF1643 k141_1003_2 351016.RAZWK3B_05392 1.66e-90 278.0 COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2TRXD@28211|Alphaproteobacteria,2P2NG@2433|Roseobacter 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_16311_1 1279019.ARQK01000047_gene1036 1.72e-197 573.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_20582_1 1123368.AUIS01000010_gene2361 2.11e-29 115.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2ND7X@225057|Acidithiobacillales 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_20582_2 1410653.JHVC01000008_gene3020 6.42e-15 73.9 2DVDQ@1|root,32UZ8@2|Bacteria,1VVZH@1239|Firmicutes,2518K@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k141_1734_1 553385.JEMF01000020_gene3043 4.36e-36 140.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales 135619|Oceanospirillales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_4518_1 1123373.ATXI01000003_gene1284 7.81e-103 315.0 COG0318@1|root,COG0318@2|Bacteria,2GH7C@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria IQ AMP-binding enzyme C-terminal domain - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_19170_1 1089550.ATTH01000001_gene2125 8.16e-18 84.7 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1FIVW@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Beta-eliminating lyase bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_3795_1 396588.Tgr7_2713 1.62e-103 313.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_3795_2 754477.Q7C_2469 1.63e-36 127.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,460P5@72273|Thiotrichales 72273|Thiotrichales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_19811_1 1297569.MESS2_1590038 1.14e-13 71.2 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,43GY2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K transcriptional regulator ptxR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0003950,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043455,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045862,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1900376,GO:1900377,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - HTH_1,LysR_substrate k141_19811_2 189426.PODO_03965 1.15e-05 48.5 2DVDQ@1|root,32UZ8@2|Bacteria,1VVZH@1239|Firmicutes,4I6NA@91061|Bacilli,26TWE@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_21939_1 1278309.KB907106_gene1264 8.27e-145 407.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XHSZ@135619|Oceanospirillales 135619|Oceanospirillales C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_21939_2 1278309.KB907106_gene1266 2.96e-49 157.0 2E9SG@1|root,333YN@2|Bacteria,1NCW7@1224|Proteobacteria,1SFGK@1236|Gammaproteobacteria,1XMB8@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_12884_1 765913.ThidrDRAFT_1703 1.58e-19 83.2 2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,1S4WN@1236|Gammaproteobacteria,1WYAX@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_12884_2 1382359.JIAL01000001_gene1984 2.74e-53 185.0 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity - - - - - - - - - - - - CCP_MauG k141_9330_3 398580.Dshi_0788 1.2e-09 58.2 COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,2TQS6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) cobT GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 ko:K00768 ko00860,ko01100,map00860,map01100 M00122 R04148 RC00033,RC00063 ko00000,ko00001,ko00002,ko01000 - - - DBI_PRT k141_17029_1 1232683.ADIMK_0867 7.17e-49 179.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_10796_1 1288826.MSNKSG1_07503 1.17e-218 606.0 COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,4643K@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily rlmM GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 ko:K06968 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_10796_2 1288826.MSNKSG1_07508 3.64e-221 624.0 COG2199@1|root,COG3264@1|root,COG3264@2|Bacteria,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1SZ5Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria MT COG2199 FOG GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_2389_1 1288826.MSNKSG1_04801 5.98e-56 180.0 COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,1RSNT@1236|Gammaproteobacteria,46603@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, ATPase component ecfA2 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_2389_2 626887.J057_22635 1.39e-43 156.0 2FFR6@1|root,347NE@2|Bacteria,1P0S4@1224|Proteobacteria,1STKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2389_3 1288826.MSNKSG1_04791 3.03e-188 540.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,469SP@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_18438_3 1117647.M5M_01180 0.000399 42.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1J51T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_9344_1 396588.Tgr7_3074 2.44e-66 209.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_12897_1 1049564.TevJSym_au00160 1.41e-53 185.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_12897_2 550540.Fbal_2757 7.81e-45 152.0 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_5914_1 697282.Mettu_3545 1.3e-14 79.7 COG1357@1|root,COG3064@1|root,COG1357@2|Bacteria,COG3064@2|Bacteria,1RE5F@1224|Proteobacteria,1T53B@1236|Gammaproteobacteria,1XEYN@135618|Methylococcales 135618|Methylococcales M TonB C terminal - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_5914_2 1283300.ATXB01000002_gene3020 2.95e-40 148.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XEH5@135618|Methylococcales 135618|Methylococcales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_1757_1 465817.ETA_21960 3.34e-90 280.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,3X4KA@551|Erwinia 1236|Gammaproteobacteria S ABC transporter, ATP-binding protein ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_10062_1 472759.Nhal_1635 3.21e-104 326.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales 135613|Chromatiales I PFAM SNARE associated Golgi protein - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc k141_7310_1 1500306.JQLA01000004_gene5645 1.93e-12 72.8 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,2U296@28211|Alphaproteobacteria,4BCQ2@82115|Rhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,GerE k141_8069_1 1123400.KB904771_gene3350 1.29e-96 307.0 COG0303@1|root,COG0746@1|root,COG1763@1|root,COG0303@2|Bacteria,COG0746@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales 72273|Thiotrichales H MoeA N-terminal region (domain I and II) - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MobB,MoeA_C,MoeA_N,NTP_transf_3 k141_14323_1 1116472.MGMO_61c00050 1.21e-35 134.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XEJ0@135618|Methylococcales 135618|Methylococcales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_7391_1 1485544.JQKP01000017_gene605 3.92e-38 138.0 28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,44UZS@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF3025) - - - - - - - - - - - - DUF3025 k141_4636_1 2340.JV46_24990 3.18e-83 262.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1J50Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,STAS_2,Sulfate_transp k141_5312_1 626887.J057_19155 5.31e-88 291.0 COG1073@1|root,COG1073@2|Bacteria,1NVTC@1224|Proteobacteria,1RNXQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1073 Hydrolases of the alpha beta superfamily - - - - - - - - - - - - Lipase_bact_N k141_17129_1 1042377.AFPJ01000016_gene126 1.42e-48 167.0 COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,46AIU@72275|Alteromonadaceae 1236|Gammaproteobacteria I Fatty acid desaturase alkB2 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase,Rubredoxin k141_18524_1 1288826.MSNKSG1_16256 1.06e-292 827.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4663R@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_2498_1 498761.HM1_3150 1.12e-10 60.1 2E4EA@1|root,32Z9I@2|Bacteria,1VG12@1239|Firmicutes,24R4R@186801|Clostridia 186801|Clostridia S ORF located using Blastx - - - - - - - - - - - - - k141_13689_1 1248232.BANQ01000086_gene2773 5.55e-43 149.0 COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1Y36B@135623|Vibrionales 135623|Vibrionales M Conserved TM helix - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_10164_2 384676.PSEEN0167 2.51e-72 234.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_9432_1 89187.ISM_17060 1.27e-89 277.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,46NJI@74030|Roseovarius 28211|Alphaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases dhaL - 1.2.1.99 ko:K09472 ko00330,ko01100,map00330,map01100 M00136 R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17881_1 400668.Mmwyl1_3693 1.19e-69 219.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1S5U0@1236|Gammaproteobacteria,1XPB0@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_17881_2 1278309.KB907101_gene772 1.07e-105 308.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XJND@135619|Oceanospirillales 135619|Oceanospirillales D Maf-like protein maf-2 - - - - - - - - - - - Maf k141_17881_3 1278309.KB907101_gene773 1.03e-23 94.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XJKJ@135619|Oceanospirillales 135619|Oceanospirillales S metal-binding, possibly nucleic acid-binding protein - - - ko:K07040 - - - - ko00000 - - - DUF177 k141_8168_1 1278309.KB907107_gene1643 1.47e-52 173.0 COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XHJV@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03717 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_8168_2 1485545.JQLW01000011_gene1349 1.61e-151 441.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria 1224|Proteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA GO:0003674,GO:0005215,GO:0005451,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006875,GO:0006883,GO:0006885,GO:0006950,GO:0006970,GO:0008150,GO:0008289,GO:0008324,GO:0009628,GO:0009651,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0042592,GO:0043157,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0055065,GO:0055067,GO:0055078,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1901611,GO:1901612,GO:1902600 - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - iSF_1195.SF0016,iSFxv_1172.SFxv_0017,iS_1188.S0018 Na_H_antiport_1 k141_10914_1 1278309.KB907099_gene2450 1.93e-40 138.0 2BY4C@1|root,32XUX@2|Bacteria,1N0C0@1224|Proteobacteria,1SAJV@1236|Gammaproteobacteria,1XM7N@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10914_2 1278309.KB907099_gene2449 1.58e-77 231.0 COG0599@1|root,COG0599@2|Bacteria,1RFQD@1224|Proteobacteria,1S451@1236|Gammaproteobacteria,1XJPM@135619|Oceanospirillales 135619|Oceanospirillales S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD k141_10914_3 1278309.KB907099_gene2448 4.5e-298 816.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1XHR7@135619|Oceanospirillales 135619|Oceanospirillales E phospho-2-dehydro-3-deoxyheptonate aldolase - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 k141_10914_4 1278971.AOGF01000024_gene1905 4.13e-16 74.7 COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,1Y95G@135625|Pasteurellales 135625|Pasteurellales S tRNA pseudouridine synthase C Z012_05475 - - - - - - - - - - - DUF446 k141_10914_5 1278309.KB907099_gene2446 2.27e-60 187.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XJZ5@135619|Oceanospirillales 135619|Oceanospirillales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_15797_2 178901.AmDm5_3082 6.34e-20 85.1 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,2U5C4@28211|Alphaproteobacteria,2JSHX@204441|Rhodospirillales 204441|Rhodospirillales L Helix-turn-helix domain of resolvase - - - - - - - - - - - - HTH_7,Resolvase k141_7392_1 1401078.HMPREF2140_08000 3.67e-29 115.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia 976|Bacteroidetes F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,ASL_C,Lyase_1 k141_7392_2 643867.Ftrac_1596 7.47e-18 83.2 COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia 976|Bacteroidetes C PFAM 2Fe-2S iron-sulfur cluster binding domain dmpP - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_12312_1 1278309.KB907101_gene629 6.31e-164 461.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1XJCH@135619|Oceanospirillales 135619|Oceanospirillales Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_11 k141_12312_2 742738.HMPREF9460_00096 2.67e-09 56.6 COG0328@1|root,COG2852@1|root,COG0328@2|Bacteria,COG2852@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,268TN@186813|unclassified Clostridiales 186801|Clostridia L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_2499_1 1423144.Gal_02091 3.68e-08 53.9 COG1638@1|root,COG1638@2|Bacteria,1NJX4@1224|Proteobacteria,2U0XM@28211|Alphaproteobacteria,34FWX@302485|Phaeobacter 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_2499_2 1423144.Gal_02090 3.3e-61 191.0 COG0790@1|root,COG0790@2|Bacteria,1RJ71@1224|Proteobacteria,2U5UE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0790 FOG TPR repeat, SEL1 subfamily - - - ko:K07126 - - - - ko00000 - - - SPOR,Sel1 k141_20653_1 1278309.KB907101_gene659 1.4e-61 212.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XHZN@135619|Oceanospirillales 135619|Oceanospirillales S DNA internalization-related competence protein ComEC Rec2 rec2 - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_20653_2 1278309.KB907101_gene658 1.06e-93 278.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XJZU@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_20653_3 1278309.KB907101_gene657 8.96e-134 382.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1XJ6X@135619|Oceanospirillales 135619|Oceanospirillales V Part of the ABC transporter complex LolCDE involved in the translocation of lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_20653_4 1278309.KB907101_gene656 3.98e-210 586.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XHFB@135619|Oceanospirillales 135619|Oceanospirillales M Lipoprotein releasing system, transmembrane protein lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_16428_1 765912.Thimo_2949 2.81e-48 175.0 28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,1WW4J@135613|Chromatiales 135613|Chromatiales S Carboxysome shell peptide mid-region - - - - - - - - - - - - CsoS2_M k141_5978_1 1304888.ATWF01000001_gene1863 6.97e-12 67.4 COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,2GFVU@200930|Deferribacteres 200930|Deferribacteres T Bacterial periplasmic substrate-binding proteins - - - - - - - - - - - - HATPase_c,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3 k141_5978_2 519989.ECTPHS_02399 3.73e-46 160.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_5314_1 1267600.JFGT01000006_gene1190 5.05e-41 145.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,3VYST@53335|Pantoea 1236|Gammaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k141_18526_1 497321.C664_00800 9.29e-37 134.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria,2KV6C@206389|Rhodocyclales 206389|Rhodocyclales L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_15798_2 545264.KB898746_gene978 2.39e-36 132.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_13712_3 1278309.KB907099_gene3101 6.11e-118 341.0 COG0179@1|root,COG0179@2|Bacteria,1R51B@1224|Proteobacteria,1RQI9@1236|Gammaproteobacteria,1XI86@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase family - - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_13712_4 1278309.KB907099_gene3100 1.05e-166 468.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,1RMWJ@1236|Gammaproteobacteria,1XHJG@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the HpcH HpaI aldolase family hpaI - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_11590_1 1464048.JNZS01000001_gene78 3.78e-15 75.5 COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4D8QP@85008|Micromonosporales 201174|Actinobacteria E asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_11590_2 187272.Mlg_1104 2.99e-40 146.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_13029_1 977880.RALTA_A1675 2.8e-40 145.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,1K07E@119060|Burkholderiaceae 28216|Betaproteobacteria F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_1841_1 1168067.JAGP01000001_gene1473 6.45e-17 76.6 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,460XQ@72273|Thiotrichales 72273|Thiotrichales J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_1841_2 519989.ECTPHS_00175 4.2e-38 129.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1WYY8@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_21394_1 1488328.JMCL01000029_gene4983 6.36e-39 142.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_21394_2 998088.B565_3683 1.59e-93 279.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1Y43T@135624|Aeromonadales 135624|Aeromonadales D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_3902_1 1278309.KB907102_gene188 1.18e-186 537.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XH5B@135619|Oceanospirillales 135619|Oceanospirillales S permease - - - - - - - - - - - - DctM k141_14337_1 187272.Mlg_1856 2.05e-60 200.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales 135613|Chromatiales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_12339_1 2340.JV46_23120 1.72e-175 499.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J4I3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_22056_1 1354722.JQLS01000008_gene2694 2.03e-16 82.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2TS0Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - - - - - - - - - - HAD,UbiA k141_22056_2 246200.SPO3084 6.23e-16 76.3 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TQTD@28211|Alphaproteobacteria,4NBF6@97050|Ruegeria 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k141_5339_1 367336.OM2255_12557 3.03e-28 115.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria 28211|Alphaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_1174_1 1288826.MSNKSG1_01913 1.89e-159 449.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,469DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component braF-2 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_13030_1 1121937.AUHJ01000003_gene3220 4.89e-80 261.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,464S9@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind k141_21395_1 1122599.AUGR01000007_gene1184 7.67e-95 288.0 2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria,1XNQZ@135619|Oceanospirillales 135619|Oceanospirillales S Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - DUF1329 k141_15823_1 631362.Thi970DRAFT_03838 2.35e-91 281.0 COG2232@1|root,COG2232@2|Bacteria 2|Bacteria V ATP-grasp domain - - - - - - - - - - - - ATP-grasp_3 k141_15823_2 631362.Thi970DRAFT_03839 3.6e-84 258.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1WYUF@135613|Chromatiales 135613|Chromatiales E Asparaginase - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 k141_16447_2 620914.JH621290_gene1520 1.88e-21 100.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HZ6D@117743|Flavobacteriia,2YICX@290174|Aquimarina 976|Bacteroidetes M Peptidase family M23 - - - - - - - - - - - - LysM,Peptidase_M23,Peptidase_M56 k141_17155_1 518766.Rmar_2758 8.98e-18 90.1 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3852@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3852@2|Bacteria,4NDXU@976|Bacteroidetes,1FJVE@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes T PAS fold - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg k141_20671_1 443152.MDG893_01100 5.37e-121 366.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,464FC@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_20671_2 1288826.MSNKSG1_08643 2.26e-40 149.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RQMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria H FOG TPR repeat - - - - - - - - - - - - Methyltransf_25,Methyltransf_31,TPR_1,TPR_11,TPR_12,TPR_16,TPR_8 k141_19312_1 1278309.KB907099_gene2378 7.74e-200 563.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XI2S@135619|Oceanospirillales 135619|Oceanospirillales J Involved in the processing of the 5'end of 16S rRNA - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_13714_1 1278309.KB907100_gene1999 1.15e-86 279.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XHH3@135619|Oceanospirillales 135619|Oceanospirillales M penicillin-binding protein mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_5340_1 96561.Dole_1595 3.26e-27 110.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MHVD@213118|Desulfobacterales 28221|Deltaproteobacteria J TIGRFAM glutaminyl-tRNA synthetase glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C k141_4655_1 1288826.MSNKSG1_06458 3.85e-186 525.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,465ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_4655_2 1288826.MSNKSG1_06453 2.57e-232 644.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b k141_19927_1 1219031.BBJR01000037_gene3156 8.92e-21 93.6 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,4AANW@80864|Comamonadaceae 28216|Betaproteobacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_19927_2 767434.Fraau_2779 1.19e-30 116.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1X61Y@135614|Xanthomonadales 135614|Xanthomonadales NU pilus assembly protein pilp pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_19927_3 1122604.JONR01000010_gene3938 3.72e-37 144.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1X3SF@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretory pathway, component HofQ pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_12340_1 675814.VIC_001214 3.6e-67 204.0 COG3791@1|root,COG3791@2|Bacteria,1N0KM@1224|Proteobacteria,1SA6W@1236|Gammaproteobacteria,1XXEM@135623|Vibrionales 135623|Vibrionales S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - GFA k141_14338_1 754477.Q7C_2025 9.03e-67 211.0 COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,463NF@72273|Thiotrichales 72273|Thiotrichales CH Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_14338_2 207954.MED92_05648 1.04e-53 176.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,1XHIM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_11591_1 715451.ambt_11835 1.35e-55 184.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_11591_2 713586.KB900536_gene2249 8.47e-49 159.0 2E1SU@1|root,32X2N@2|Bacteria,1N4HW@1224|Proteobacteria,1SAEX@1236|Gammaproteobacteria,1X167@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_21396_1 519989.ECTPHS_03437 3.51e-69 220.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WXHR@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k141_21396_2 997884.HMPREF1068_03006 0.000666 43.5 COG0642@1|root,COG0745@1|root,COG1879@1|root,COG2207@1|root,COG0745@2|Bacteria,COG1879@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMGE@815|Bacteroidaceae 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Peripla_BP_4,Response_reg k141_18549_2 396595.TK90_2382 1.08e-59 197.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1WX1N@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_13031_1 1288826.MSNKSG1_08868 1.65e-215 597.0 28HEC@1|root,2Z7QS@2|Bacteria,1N54Y@1224|Proteobacteria,1SA2G@1236|Gammaproteobacteria,4654V@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15825_1 1122599.AUGR01000021_gene3200 6.81e-92 285.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XHTQ@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 k141_16450_1 405948.SACE_2456 1.71e-27 108.0 2DNU1@1|root,32Z4S@2|Bacteria,2I3QM@201174|Actinobacteria,4EATF@85010|Pseudonocardiales 201174|Actinobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_17156_1 225937.HP15_3948 9.77e-93 293.0 COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1RQZW@1236|Gammaproteobacteria,464FX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_17156_2 663610.JQKO01000016_gene1605 1.56e-19 84.7 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,3NCED@45404|Beijerinckiaceae 28211|Alphaproteobacteria T Transcriptional regulatory protein, C terminal - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_13032_1 41431.PCC8801_1350 5.81e-52 186.0 COG0745@1|root,COG3829@1|root,COG5001@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,3KG35@43988|Cyanothece 1117|Cyanobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_19928_1 493475.GARC_1017 1.91e-175 503.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,464PW@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iJN746.PP_2845 Amidohydro_1,Urease_alpha k141_3323_2 1278309.KB907100_gene2165 8.83e-06 46.6 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XIF6@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_12410_1 406818.XBJ1_4186 2.08e-102 317.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_13780_1 1232437.KL662043_gene2227 1.01e-81 253.0 COG3026@1|root,COG3026@2|Bacteria,1R2P2@1224|Proteobacteria,43DHF@68525|delta/epsilon subdivisions,2X8P9@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_10256_1 1288826.MSNKSG1_13012 9.28e-167 470.0 COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,46AM8@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_10256_2 1288826.MSNKSG1_13017 3.66e-186 550.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,464U2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_10992_1 663278.Ethha_1753 1.21e-78 236.0 COG1943@1|root,COG1943@2|Bacteria,1V53Y@1239|Firmicutes,25CMQ@186801|Clostridia,3WRVH@541000|Ruminococcaceae 186801|Clostridia L PFAM transposase IS200-family protein - - - - - - - - - - - - Y1_Tnp k141_14380_1 396588.Tgr7_0560 9.56e-32 124.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_14380_2 322710.Avin_46780 5.37e-85 258.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria 1236|Gammaproteobacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_14380_3 1049564.TevJSym_ao00360 1.65e-129 380.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1J50Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_1245_1 1123401.JHYQ01000015_gene1405 1.39e-97 306.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales 72273|Thiotrichales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_3324_1 314271.RB2654_07656 5.13e-51 171.0 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,2TSFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type proline glycine betaine transport systems, periplasmic components - - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_22107_1 1278309.KB907111_gene3399 2.41e-25 102.0 COG4974@1|root,COG4974@2|Bacteria,1PZTE@1224|Proteobacteria,1RPTV@1236|Gammaproteobacteria,1XHRV@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_20710_2 1288826.MSNKSG1_04786 4.47e-161 451.0 COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria,465B6@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0209 Ribonucleotide reductase, alpha subunit nrdJb - - - - - - - - - - - - k141_20710_3 1288826.MSNKSG1_04791 0.0 939.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,469SP@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_1914_2 643867.Ftrac_0276 7.03e-09 56.2 28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_18616_1 754477.Q7C_775 9.81e-67 210.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,46036@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_3958_1 1168067.JAGP01000001_gene951 1.51e-12 67.8 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales 72273|Thiotrichales O Peptidylprolyl isomerase - - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_3958_2 187272.Mlg_2285 5.37e-37 126.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1WYVU@135613|Chromatiales 135613|Chromatiales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_533_1 1288826.MSNKSG1_13817 7.32e-68 213.0 COG0583@1|root,COG0583@2|Bacteria,1QN6R@1224|Proteobacteria,1RSKY@1236|Gammaproteobacteria,466I6@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_18002_1 1288826.MSNKSG1_05626 4.54e-97 284.0 COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,1SG1X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - AAA_33,Zeta_toxin k141_18002_2 1288826.MSNKSG1_05621 2.32e-88 260.0 2DMJX@1|root,32S2S@2|Bacteria,1N4UR@1224|Proteobacteria,1SBGD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - - - - - - - - - - ParD_like k141_18002_3 1288826.MSNKSG1_05616 6.71e-114 328.0 28VMV@1|root,2ZHQ1@2|Bacteria,1P4I5@1224|Proteobacteria,1SV1N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18002_4 1288826.MSNKSG1_05611 9.97e-51 160.0 COG2841@1|root,COG2841@2|Bacteria,1NDHE@1224|Proteobacteria,1SDIQ@1236|Gammaproteobacteria,468UG@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VPA0402 - - ko:K09794 - - - - ko00000 - - - DUF465 k141_18002_5 1288826.MSNKSG1_05606 2.39e-226 624.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,46489@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360 ACP_syn_III,ACP_syn_III_C k141_18002_6 1288826.MSNKSG1_05601 1.59e-148 441.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,469QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_12426_2 1265503.KB905163_gene2231 3.03e-28 110.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,2Q6D4@267889|Colwelliaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt k141_1264_1 1288826.MSNKSG1_06578 2.49e-77 238.0 COG2885@1|root,COG2885@2|Bacteria,1NF3D@1224|Proteobacteria,1SBSW@1236|Gammaproteobacteria,468ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function (DUF4892) - - - - - - - - - - - - DUF4892 k141_1264_2 1288826.MSNKSG1_06583 1.87e-215 595.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1S6CX@1236|Gammaproteobacteria,466RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_1264_3 1288826.MSNKSG1_06588 5.94e-80 237.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,467AW@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3215 Tfp pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_1264_4 1288826.MSNKSG1_06593 2.41e-236 651.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,466TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0470 ATPase involved in DNA replication holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_1264_5 1288826.MSNKSG1_06598 0.0 1309.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,464NQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes tgpA - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_1264_6 1288826.MSNKSG1_06603 1.05e-210 584.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,466X1@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_6070_1 426114.THI_1782 1.28e-14 77.4 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VU27@28216|Betaproteobacteria,1KPJP@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp k141_14391_2 405948.SACE_2539 7.36e-38 132.0 COG2391@1|root,COG2391@2|Bacteria,2IGU9@201174|Actinobacteria 201174|Actinobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_14391_3 159749.K0T654 8.41e-06 52.0 2DG6W@1|root,2S5TV@2759|Eukaryota 2759|Eukaryota S Sulphur transport - - - - - - - - - - - - Sulf_transp k141_13106_1 207954.MED92_15028 9.08e-109 327.0 COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,1T1XV@1236|Gammaproteobacteria,1XJ40@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,sCache_2 k141_13106_2 207954.MED92_15023 6.19e-101 298.0 COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1XJ8V@135619|Oceanospirillales 135619|Oceanospirillales K response regulator - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_13106_3 298386.PBPRA1136 2.04e-56 204.0 COG0840@1|root,COG1074@1|root,COG0840@2|Bacteria,COG1074@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUGQ@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_22129_1 1190603.AJYD01000094_gene3539 7e-57 208.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XV3Y@135623|Vibrionales 135623|Vibrionales NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,PAS_8,PAS_9 k141_18642_1 1121396.KB893024_gene3903 1.31e-88 282.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,2MM2H@213118|Desulfobacterales 28221|Deltaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase arnT - - - - - - - - - - - PMT,PMT_2 k141_15137_1 1278309.KB907099_gene2981 1.11e-113 334.0 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,1XJ7T@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k141_3971_1 998674.ATTE01000001_gene4378 1.19e-80 254.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales 72273|Thiotrichales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_7510_1 1304883.KI912532_gene2537 8.41e-12 63.5 2EI92@1|root,33C0E@2|Bacteria,1NHN6@1224|Proteobacteria,2VYC9@28216|Betaproteobacteria,2KXI8@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_17234_2 765912.Thimo_2945 3.42e-126 378.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,1WWYA@135613|Chromatiales 135613|Chromatiales CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_1265_1 89187.ISM_15205 1.75e-13 73.2 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,46PUZ@74030|Roseovarius 28211|Alphaproteobacteria M N-acetylmuramoyl-L-alanine amidase, family 3 amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 k141_12427_1 1266925.JHVX01000005_gene1848 6.59e-48 167.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_21469_1 395493.BegalDRAFT_2224 4.47e-36 130.0 COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S mRNA catabolic process - - - - - - - - - - - - - k141_21469_2 765910.MARPU_15680 7.02e-202 570.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales 135613|Chromatiales C PFAM malic - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_18643_1 504472.Slin_0322 2.4e-45 156.0 COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,47JXA@768503|Cytophagia 976|Bacteroidetes S PFAM YicC-like family, N-terminal region - - - - - - - - - - - - DUF1732,YicC_N k141_19992_1 1278309.KB907102_gene182 1.84e-15 73.9 COG2384@1|root,COG2384@2|Bacteria,1RBQ3@1224|Proteobacteria,1S2DU@1236|Gammaproteobacteria,1XKCI@135619|Oceanospirillales 135619|Oceanospirillales S tRNA (adenine(22)-N(1))-methyltransferase - - 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_18 k141_19992_2 1316927.ATKI01000046_gene686 3.41e-15 71.2 COG0236@1|root,COG0236@2|Bacteria,1QA4X@1224|Proteobacteria,1RVPH@1236|Gammaproteobacteria,1YU7U@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding k141_19992_3 1116375.VEJY3_20386 1.42e-83 262.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,1RXCZ@1236|Gammaproteobacteria,1Y0WE@135623|Vibrionales 135623|Vibrionales C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_22130_2 1304885.AUEY01000022_gene3393 4.74e-66 218.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MHZK@213118|Desulfobacterales 28221|Deltaproteobacteria EH TIGRFAM acetolactate synthase, large subunit, biosynthetic type - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_13803_1 1219065.VPR01S_09_01710 5.61e-47 163.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1XTJ9@135623|Vibrionales 135623|Vibrionales P Mg2 and Co2 transporter CorB yfjD - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_13803_2 396588.Tgr7_0843 2.04e-26 103.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales 135613|Chromatiales S Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_6071_1 1123360.thalar_03336 2.86e-10 60.8 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_6071_2 999611.KI421504_gene711 4.83e-50 167.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,27ZIC@191028|Leisingera 28211|Alphaproteobacteria O GrpE grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_2589_1 305900.GV64_01795 7.07e-59 198.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XHSI@135619|Oceanospirillales 135619|Oceanospirillales P Trk system potassium uptake protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_14392_2 1288826.MSNKSG1_06488 1.53e-43 149.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,468K7@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_3345_2 1026882.MAMP_01297 1.19e-44 152.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,460ZS@72273|Thiotrichales 72273|Thiotrichales D Peptidase family M23 - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_16537_1 1177154.Y5S_01513 5.87e-54 180.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1XH40@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_9513_1 439235.Dalk_1657 3.46e-46 159.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2MIHM@213118|Desulfobacterales 28221|Deltaproteobacteria M Polysaccharide biosynthesis protein - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_9513_2 1408428.JNJP01000016_gene2066 2.4e-09 60.5 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42Q4Y@68525|delta/epsilon subdivisions,2WKZT@28221|Deltaproteobacteria,2M8BB@213115|Desulfovibrionales 28221|Deltaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_3972_1 1121335.Clst_0420 1.71e-45 162.0 COG3464@1|root,COG4584@1|root,COG3464@2|Bacteria,COG4584@2|Bacteria,1VDMT@1239|Firmicutes,25H3E@186801|Clostridia,3WSDV@541000|Ruminococcaceae 186801|Clostridia L COG 3464 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_ISL3 k141_17235_1 1189612.A33Q_0850 5.25e-126 369.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,47MA2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_6728_1 1232683.ADIMK_0867 4.56e-117 370.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_12428_1 1353528.DT23_08230 2.63e-66 211.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,2XM6H@285107|Thioclava 28211|Alphaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_13804_1 1121904.ARBP01000016_gene5207 6.4e-45 155.0 COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia 976|Bacteroidetes J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM k141_8838_1 492774.JQMB01000002_gene1260 2.47e-15 78.6 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TQV2@28211|Alphaproteobacteria,4B966@82115|Rhizobiaceae 28211|Alphaproteobacteria C Glycerol-3-phosphate dehydrogenase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_8838_2 268407.PWYN_17120 2.23e-11 69.7 COG0584@1|root,COG0584@2|Bacteria,1V1B3@1239|Firmicutes,4HGMK@91061|Bacilli,26T3N@186822|Paenibacillaceae 91061|Bacilli C -phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_8838_3 6238.CBG18684 4.56e-13 68.2 COG0724@1|root,KOG0108@2759|Eukaryota,3AB6A@33154|Opisthokonta,3BUDI@33208|Metazoa,3DBVZ@33213|Bilateria,40EVR@6231|Nematoda,1KX5U@119089|Chromadorea,413W6@6236|Rhabditida 33208|Metazoa A RNA binding - GO:0003674,GO:0005488,GO:0005515 - - - - - - - - - - RRM_1 k141_541_1 626887.J057_20630 4.41e-61 196.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,4649H@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_541_2 595494.Tola_0947 1.29e-43 152.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1Y3EY@135624|Aeromonadales 135624|Aeromonadales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_18644_1 519989.ECTPHS_09308 2.01e-25 103.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria,1WZ2D@135613|Chromatiales 135613|Chromatiales S DUF218 domain - - - - - - - - - - - - DUF218 k141_18644_2 90813.JQMT01000001_gene132 1.32e-23 99.4 COG0745@1|root,COG0745@2|Bacteria,1R7VB@1224|Proteobacteria,1S026@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator receiver - - - - - - - - - - - - HATPase_c_2,Response_reg k141_10280_1 1163617.SCD_n02729 4.73e-110 326.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria 28216|Betaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH k141_10280_2 1123226.KB899287_gene3586 4.27e-24 109.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26QU5@186822|Paenibacillaceae 91061|Bacilli NT chemotaxis protein - - - - - - - - - - - - HAMP,MCPsignal k141_19368_1 1278309.KB907099_gene3045 2.02e-217 611.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XHA7@135619|Oceanospirillales 135619|Oceanospirillales P Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_19368_2 1278309.KB907099_gene3046 9.57e-63 199.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1XIX0@135619|Oceanospirillales 135619|Oceanospirillales S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_1932_1 203122.Sde_1477 2.19e-96 302.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,4640D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_16538_1 1123360.thalar_03033 1.42e-96 302.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_14393_1 1499686.BN1079_02532 6.1e-38 138.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Radical SAM - - - - - - - - - - - - Radical_SAM k141_18004_1 1121440.AUMA01000010_gene442 9.13e-18 94.4 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions,2WJVA@28221|Deltaproteobacteria,2M8BT@213115|Desulfovibrionales 28221|Deltaproteobacteria T ATP-binding region ATPase domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA,NMT1,PAS_3,PAS_4,PAS_9,dCache_1,sCache_2 k141_13108_1 1288826.MSNKSG1_05116 3.66e-199 552.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,464XV@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_21471_1 314265.R2601_10899 1.58e-110 328.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component tauC - - ko:K15552 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 k141_13805_1 1005395.CSV86_27132 5.15e-103 318.0 COG0840@1|root,COG0840@2|Bacteria,1MWU2@1224|Proteobacteria,1RR1Q@1236|Gammaproteobacteria,1YWP4@136845|Pseudomonas putida group 1236|Gammaproteobacteria NT chemotaxis - - - - - - - - - - - - MCPsignal k141_18645_1 2340.JV46_26680 2.96e-95 288.0 COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NiFe/NiFeSe hydrogenase small subunit C-terminal - - 1.12.99.6 ko:K06282 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFe_hyd_SSU_C,Oxidored_q6 k141_6763_1 270374.MELB17_14331 2.51e-279 781.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,465BK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_6763_2 270374.MELB17_14336 1.99e-71 229.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1SYUH@1236|Gammaproteobacteria,464G2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_16597_1 1049564.TevJSym_au00070 3.41e-44 159.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,1JAAK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_10346_1 1411685.U062_00920 1.05e-202 590.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J8EY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T PEP-utilising enzyme, N-terminal ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08483,ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_10346_2 1278309.KB907100_gene1959 5.02e-206 585.0 COG1807@1|root,COG1807@2|Bacteria,1RE4T@1224|Proteobacteria,1S5IF@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_21523_1 187272.Mlg_2059 2.27e-69 221.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RQ9K@1236|Gammaproteobacteria 1236|Gammaproteobacteria C alcohol dehydrogenase - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_6773_1 1278309.KB907101_gene400 0.0 2422.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_6773_2 1278309.KB907101_gene399 1.84e-97 284.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1T01F@1236|Gammaproteobacteria,1XRPB@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_6773_3 1278309.KB907101_gene398 8.34e-160 453.0 COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,1XJD3@135619|Oceanospirillales 135619|Oceanospirillales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_6773_4 1278309.KB907101_gene397 8.1e-38 127.0 2CK8I@1|root,3342W@2|Bacteria,1NBFX@1224|Proteobacteria,1SFT6@1236|Gammaproteobacteria,1XMHN@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6773_5 1278309.KB907101_gene396 1.15e-97 285.0 COG0655@1|root,COG0655@2|Bacteria,1RAP5@1224|Proteobacteria,1S3B1@1236|Gammaproteobacteria,1XJES@135619|Oceanospirillales 135619|Oceanospirillales S Flavodoxin - - - - - - - - - - - - FMN_red k141_6773_6 1232683.ADIMK_3816 4.77e-79 248.0 COG4360@1|root,COG4360@2|Bacteria,1RDRJ@1224|Proteobacteria,1S7FD@1236|Gammaproteobacteria 1236|Gammaproteobacteria F ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) - - 2.7.7.53 ko:K00988 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - ATP_transf k141_7547_1 1038860.AXAP01000002_gene4850 5.57e-97 303.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,3JWHS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_15955_1 314231.FP2506_02475 2.13e-08 55.5 COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2PJMW@255475|Aurantimonadaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family MA20_24420 - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 k141_15955_2 1201293.AKXQ01000019_gene1127 6.13e-222 630.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T402@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,SBP_bac_3 k141_15955_3 1123355.JHYO01000003_gene2922 3.83e-187 532.0 COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,2VF2T@28211|Alphaproteobacteria,370M4@31993|Methylocystaceae 28211|Alphaproteobacteria T HD domain - - - - - - - - - - - - HD k141_19415_1 1168067.JAGP01000001_gene2076 3.16e-14 70.5 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,4633S@72273|Thiotrichales 72273|Thiotrichales - - - - - ko:K09004 - - - - ko00000 - - - DrsE k141_19415_2 472759.Nhal_1250 2.18e-99 298.0 COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,1S31N@1236|Gammaproteobacteria,1WXP2@135613|Chromatiales 135613|Chromatiales G PFAM Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_19415_3 1116472.MGMO_120c00580 3.43e-91 282.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - SpoIIM k141_14446_1 1056512.D515_03399 3.83e-149 432.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,1Y0FR@135623|Vibrionales 135623|Vibrionales S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_14446_2 1298593.TOL_3685 1.18e-107 322.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1XJ47@135619|Oceanospirillales 135619|Oceanospirillales S A predicted alpha-helical domain with a conserved ER motif. - - - - - - - - - - - - Alpha-E k141_14446_3 1134474.O59_003233 4.78e-282 808.0 COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,1RPDC@1236|Gammaproteobacteria,1FGT5@10|Cellvibrio 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - Alpha-E,CP_ATPgrasp_2 k141_8312_1 261292.Nit79A3_1086 2.23e-05 52.8 28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,372VN@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_9577_1 1122599.AUGR01000015_gene2602 9.24e-19 77.8 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria,1XQB9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_588_2 391615.ABSJ01000050_gene1235 4.65e-57 179.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1J6FI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU PilZ domain pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_16599_1 1123054.KB907701_gene1792 3.79e-06 52.0 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WZ55@135613|Chromatiales 135613|Chromatiales T HDOD domain - - - - - - - - - - - - HDOD k141_4800_1 565045.NOR51B_905 5.1e-24 100.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_4800_2 305900.GV64_03875 4.45e-77 250.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XHXQ@135619|Oceanospirillales 135619|Oceanospirillales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_15956_1 765911.Thivi_3136 2.11e-85 267.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k141_18068_1 10042.XP_006989021.1 7.18e-08 61.6 COG0457@1|root,COG3914@1|root,KOG1124@2759|Eukaryota,KOG4626@2759|Eukaryota,38DM6@33154|Opisthokonta,3BEU3@33208|Metazoa,3CW6P@33213|Bilateria,485D1@7711|Chordata,48XAY@7742|Vertebrata,3J72H@40674|Mammalia,35IEN@314146|Euarchontoglires,4PZZ4@9989|Rodentia 33208|Metazoa O tetratricopeptide repeat TTC6 - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 k141_18068_2 747.DR93_2040 2.57e-51 175.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,1RWVW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Lactamase_B,Lactamase_B_2 k141_21524_2 1288826.MSNKSG1_09643 2.9e-95 301.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,463YS@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit phaA - 1.6.5.3 ko:K00341,ko:K05559 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,3.D.1 - - DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N k141_8313_1 644107.SL1157_0695 9.23e-39 139.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,4NBSD@97050|Ruegeria 28211|Alphaproteobacteria H Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC k141_8313_2 1569209.BBPH01000240_gene3377 1.35e-16 79.3 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2PUX2@265|Paracoccus 28211|Alphaproteobacteria I Acetyl-CoA dehydrogenase C-terminal like - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_10348_1 1298593.TOL_0598 4.27e-97 292.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales 135619|Oceanospirillales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_13855_1 1158292.JPOE01000002_gene2193 2.19e-68 216.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,1KJW3@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Aldo/keto reductase family tas - - - - - - - - - - - Aldo_ket_red k141_13855_3 522772.Dacet_1152 1.58e-10 63.2 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2GF7H@200930|Deferribacteres 200930|Deferribacteres T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_17294_1 411684.HPDFL43_14467 3.56e-86 268.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria,43M6Z@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the peptidase M50B family - - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - CBS,Peptidase_M50 k141_18718_1 1439940.BAY1663_01811 3.23e-94 310.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_6774_1 633131.TR2A62_2101 5.83e-47 161.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the ompA family yiaD - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_YMGG,OmpA k141_6774_2 1123247.AUIJ01000003_gene1989 8.37e-11 61.6 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Methyltransferase ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_18 k141_3998_1 634500.EbC_38160 2.03e-17 84.0 COG3300@1|root,COG5001@1|root,COG3300@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase ydcR - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MHYT k141_3998_2 1288826.MSNKSG1_15641 2.95e-151 425.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,466CT@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0000166,GO:0003674,GO:0003824,GO:0004733,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0010181,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019842,GO:0032553,GO:0032991,GO:0034641,GO:0036094,GO:0042301,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902444 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_3998_3 1288826.MSNKSG1_15636 5.85e-167 467.0 COG2091@1|root,COG2091@2|Bacteria,1R9EK@1224|Proteobacteria,1S0UM@1236|Gammaproteobacteria,46BMD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the P-Pant transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_3998_4 1288826.MSNKSG1_15631 1.87e-136 386.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,466DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2818 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_3998_5 1288826.MSNKSG1_15626 2.71e-60 186.0 2E2CT@1|root,32XHQ@2|Bacteria 2|Bacteria S cation transporter - - - - - - - - - - - - - k141_3998_6 1288826.MSNKSG1_15621 2.72e-95 278.0 2DR7N@1|root,33AJV@2|Bacteria,1NGUY@1224|Proteobacteria,1SGQC@1236|Gammaproteobacteria,468F9@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF3429) VPA1252 - - - - - - - - - - - DUF3429 k141_3998_7 1288826.MSNKSG1_15616 6.58e-223 616.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,464VE@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth - - - - - - - - - - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_3998_8 1288826.MSNKSG1_15611 0.0 952.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,4658P@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0527 Aspartokinases lysC GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_3998_9 1288826.MSNKSG1_15606 6.02e-307 836.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,46611@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family ectB GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_3998_10 1288826.MSNKSG1_15601 3.2e-124 353.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,467KA@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ectA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_3998_11 1288826.MSNKSG1_15596 3.71e-210 582.0 COG0622@1|root,COG0622@2|Bacteria,1QXG9@1224|Proteobacteria,1S3Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphoesterase - - - - - - - - - - - - - k141_3998_12 1288826.MSNKSG1_15591 0.0 885.0 COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria,1RP4J@1236|Gammaproteobacteria,46AUG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_1970_1 187272.Mlg_0848 3.59e-114 340.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_10349_1 335283.Neut_2269 7.48e-65 221.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,373XP@32003|Nitrosomonadales 28216|Betaproteobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_15157_1 1288826.MSNKSG1_09718 5.5e-71 223.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,464MW@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_15157_3 1288826.MSNKSG1_09708 1.15e-161 452.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,466IP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cpxR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_15157_4 1288826.MSNKSG1_09703 8.67e-311 847.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,466X6@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase cpxA - 2.7.13.3 ko:K07640 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_15157_6 1288826.MSNKSG1_09698 4.19e-137 388.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,4672X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein family UPF0029 yigZ - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - DUF1949,UPF0029 k141_15157_7 1288826.MSNKSG1_09693 1.33e-109 317.0 2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria,468YF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 k141_9578_1 520709.F985_04061 1.53e-64 207.0 COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,1RMRQ@1236|Gammaproteobacteria,3NKXD@468|Moraxellaceae 1236|Gammaproteobacteria C GXGXG motif - - 2.1.1.21 ko:K22082 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - GXGXG k141_9578_2 491952.Mar181_2510 5.65e-87 268.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XIUD@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamate synthase family - - 2.1.1.21 ko:K22083 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - Glu_synthase,zf-CDGSH k141_20760_1 1288826.MSNKSG1_13922 3.11e-166 475.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,465CT@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport ethA GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 1.14.13.22 ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 - R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko01000 - - - FMO-like,NAD_binding_8,Pyr_redox_3 k141_20760_2 1288826.MSNKSG1_13927 1.11e-55 186.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,4675Z@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR k141_18719_2 1499967.BAYZ01000060_gene5985 1.89e-08 58.9 COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,2NR14@2323|unclassified Bacteria 2|Bacteria U Patatin-like phospholipase CP_0464 - - ko:K01999,ko:K07001 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Patatin,cNMP_binding k141_589_1 522373.Smlt2265 6.56e-58 194.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1X322@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar motor protein motB1 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_589_2 247633.GP2143_07579 3.16e-23 95.1 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1J5TS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning XCC1889 - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_14448_1 266265.Bxe_A2276 1.89e-51 179.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,1K1NK@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_15957_1 1288826.MSNKSG1_13872 1.87e-197 557.0 COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPJY@1236|Gammaproteobacteria,4642J@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport - - 1.14.13.22 ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 - R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko01000 - - - FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_3 k141_13174_1 519989.ECTPHS_12938 1.37e-70 221.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1WY4J@135613|Chromatiales 135613|Chromatiales P Protein of unknown function DUF47 - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_13174_2 765912.Thimo_0133 8.25e-189 530.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales 135613|Chromatiales H Belongs to the ALAD family - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_8314_1 1288826.MSNKSG1_05471 8.7e-195 550.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,465MD@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1070 Sugar (pentulose and hexulose) kinases ygcE - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_18069_1 1288826.MSNKSG1_05151 1.91e-256 726.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_11713_1 411902.CLOBOL_02076 3.87e-23 103.0 COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,222KK@1506553|Lachnoclostridium 186801|Clostridia T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Response_reg k141_7548_1 1278309.KB907099_gene2831 0.0 1044.0 COG0591@1|root,COG1842@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,1QX2W@1224|Proteobacteria,1RZNE@1236|Gammaproteobacteria,1XJ1J@135619|Oceanospirillales 135619|Oceanospirillales EKT Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - - k141_12499_1 1288826.MSNKSG1_10618 3.28e-51 162.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,4693D@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 k141_12499_2 1288826.MSNKSG1_10623 5.95e-191 529.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,466H0@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0247 Fe-S oxidoreductase lldE - - ko:K18928 - - - - ko00000 - - - CCG k141_12499_3 1288826.MSNKSG1_10628 4.01e-81 247.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,465J0@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_3397_1 243277.VC_A0580 6.27e-27 104.0 COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1XWX9@135623|Vibrionales 135623|Vibrionales Q protein possibly involved in aromatic compounds catabolism ydiI - - - - - - - - - - - 4HBT k141_3397_2 1278309.KB907101_gene753 0.0 965.0 COG0738@1|root,COG0738@2|Bacteria,1QUEB@1224|Proteobacteria,1T1VW@1236|Gammaproteobacteria,1XS1K@135619|Oceanospirillales 135619|Oceanospirillales G Sugar (and other) transporter - - - - - - - - - - - - MFS_1 k141_3397_3 1278309.KB907101_gene756 9.08e-73 220.0 COG0454@1|root,COG0456@2|Bacteria,1REK9@1224|Proteobacteria,1S5AI@1236|Gammaproteobacteria,1XJUW@135619|Oceanospirillales 135619|Oceanospirillales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_3397_4 1278309.KB907101_gene757 6.02e-59 189.0 COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,1S37V@1236|Gammaproteobacteria,1XIDB@135619|Oceanospirillales 135619|Oceanospirillales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_10350_2 467661.RKLH11_1181 6.51e-60 198.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,3ZGXF@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_15958_1 765910.MARPU_12475 5.26e-11 63.2 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales 135613|Chromatiales S pfam rdd - - - - - - - - - - - - RDD k141_15958_2 754477.Q7C_2503 5.41e-22 94.7 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,460N2@72273|Thiotrichales 72273|Thiotrichales S Permease YjgP YjgQ lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_18070_2 765912.Thimo_1182 1.07e-09 60.8 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1WWXD@135613|Chromatiales 135613|Chromatiales C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_17,Fer4_7,Fer4_8 k141_18738_1 1234364.AMSF01000080_gene3054 3.7e-90 290.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1X5HN@135614|Xanthomonadales 135614|Xanthomonadales L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k141_9592_1 1288826.MSNKSG1_05151 2.37e-129 393.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_13219_1 1278309.KB907110_gene3190 8.48e-183 524.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1XHUX@135619|Oceanospirillales 135619|Oceanospirillales T PrkA family serine protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_13219_2 1278309.KB907110_gene3191 1.46e-269 742.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1XHCJ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0229 family - - - ko:K09786 - - - - ko00000 - - - DUF444 k141_13219_3 1278309.KB907110_gene3192 9.11e-156 448.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1XHQQ@135619|Oceanospirillales 135619|Oceanospirillales S SpoVR family - - - - - - - - - - - - SpoVR k141_3445_1 998674.ATTE01000001_gene417 1.53e-100 310.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4623I@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein CcmF C-terminal - - - - - - - - - - - - CcmF_C,Cytochrom_C_asm k141_7573_1 1187851.A33M_3258 2.45e-27 110.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,3FE31@34008|Rhodovulum 28211|Alphaproteobacteria G HpcH/HpaI aldolase/citrate lyase family hpaI GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0008150,GO:0008152,GO:0016829,GO:0016830,GO:0016832,GO:0044238,GO:0044424,GO:0044464,GO:0071704 4.1.2.20,4.1.2.52 ko:K01630,ko:K02510 ko00053,ko00350,ko01120,map00053,map00350,map01120 - R01645,R01647,R02754,R03277 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_7573_2 1217720.ALOX01000094_gene3882 2.26e-67 221.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JQ5K@204441|Rhodospirillales 204441|Rhodospirillales EG Belongs to the IlvD Edd family - - 4.2.1.82,4.2.1.9 ko:K01687,ko:K22186 ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02429,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_11118_1 1461693.ATO10_04152 6.26e-31 115.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2TRDH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_11118_2 314232.SKA53_00420 4.2e-32 118.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,2U8XN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - DUF3833 k141_18119_1 472759.Nhal_1513 6.34e-137 394.0 COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales 135613|Chromatiales V (ABC) transporter - - - - - - - - - - - - - k141_18119_2 396588.Tgr7_0495 1.1e-149 429.0 COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1WWUS@135613|Chromatiales 135613|Chromatiales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metAS - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS k141_618_1 545264.KB898749_gene141 5.03e-77 235.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X0W2@135613|Chromatiales 135613|Chromatiales S PFAM cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_14490_1 761193.Runsl_1431 6.07e-61 205.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia 976|Bacteroidetes E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_8926_1 1288826.MSNKSG1_16241 1.15e-50 171.0 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,467MC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase regB - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_8926_2 1288826.MSNKSG1_16246 0.0 934.0 COG4206@1|root,COG4206@2|Bacteria,1QUPS@1224|Proteobacteria,1T2KE@1236|Gammaproteobacteria,467H2@72275|Alteromonadaceae 1236|Gammaproteobacteria H TonB dependent receptor oprC - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18753_1 105559.Nwat_0192 2.04e-45 154.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WYU5@135613|Chromatiales 135613|Chromatiales P PFAM Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_18753_3 1249627.D779_0301 7.17e-66 204.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales 135613|Chromatiales K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_1361_1 349124.Hhal_0898 3.12e-17 80.9 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_1361_2 264730.PSPPH_4504 8.06e-65 201.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1Z4J5@136849|Pseudomonas syringae group 1236|Gammaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0380 DMRL_synthase k141_17327_1 768671.ThimaDRAFT_3706 4.95e-175 512.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WWTA@135613|Chromatiales 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family aoxB - - - - - - - - - - - Molybdopterin,Molydop_binding k141_20795_1 1354722.JQLS01000008_gene2139 4.62e-16 81.6 COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2TVJN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane-associated, metal-dependent hydrolase eptA - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1705,Sulfatase k141_20795_2 42565.FP66_16105 1.42e-34 123.0 COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XJVH@135619|Oceanospirillales 135619|Oceanospirillales K XRE family transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3 k141_8353_1 1278309.KB907105_gene1447 1.53e-153 439.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,1RPSG@1236|Gammaproteobacteria,1XIG7@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0324 family - - - - - - - - - - - - Cons_hypoth698 k141_619_1 1163408.UU9_13678 2.11e-62 200.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1X3U6@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_6166_1 1191523.MROS_2323 5.97e-31 112.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_6166_2 261292.Nit79A3_2501 2.84e-90 277.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,374M1@32003|Nitrosomonadales 28216|Betaproteobacteria L PFAM Integrase, catalytic core - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_5514_1 545264.KB898744_gene1992 2.41e-27 111.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_18120_1 1504981.KO116_4759 3.34e-54 178.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SZ7I@1236|Gammaproteobacteria,1XRME@135619|Oceanospirillales 135619|Oceanospirillales S Electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_18120_2 1122201.AUAZ01000002_gene1114 1.33e-13 70.1 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,1S3HN@1236|Gammaproteobacteria,468J6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_15988_1 1255043.TVNIR_0568 5.18e-103 307.0 28I2K@1|root,2ZAEK@2|Bacteria,1R9HK@1224|Proteobacteria,1SJV2@1236|Gammaproteobacteria,1X001@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_15182_1 765910.MARPU_14315 1.88e-12 67.4 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WXBN@135613|Chromatiales 135613|Chromatiales C PFAM FAD linked oxidase domain protein - - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_15182_2 886293.Sinac_3316 2.34e-18 82.0 COG0792@1|root,COG0792@2|Bacteria,2J0GX@203682|Planctomycetes 203682|Planctomycetes L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_15182_3 472759.Nhal_0475 5.41e-23 101.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales 135613|Chromatiales M PFAM LppC - - - ko:K07121 - - - - ko00000 - - - LppC k141_10391_1 1288826.MSNKSG1_12557 3.33e-196 548.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,46ADB@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4175 ABC-type proline glycine betaine transport system, ATPase component - - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_10391_2 1288826.MSNKSG1_12552 6.58e-231 637.0 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,466J0@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4176 ABC-type proline glycine betaine transport system, permease component opuAB - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_10391_3 1288826.MSNKSG1_12547 7.23e-64 203.0 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,1RQ3U@1236|Gammaproteobacteria,466HM@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2113 ABC-type proline glycine betaine transport systems, periplasmic components opuAC - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_19456_2 500640.CIT292_06041 4.47e-17 80.9 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1RN9I@1236|Gammaproteobacteria,3WWAB@544|Citrobacter 1236|Gammaproteobacteria S Phospholipase/Carboxylesterase ypfH GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_13898_1 1278309.KB907101_gene677 8.75e-56 178.0 COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,1S4MZ@1236|Gammaproteobacteria,1XK3G@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_13898_2 1504981.KO116_4307 6.79e-121 359.0 COG3047@1|root,COG3047@2|Bacteria,1R23G@1224|Proteobacteria,1T5G3@1236|Gammaproteobacteria,1XS2K@135619|Oceanospirillales 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13898_3 1207075.PputUW4_03094 4.38e-05 49.3 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_20796_1 1122137.AQXF01000001_gene2896 1.06e-57 194.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_13220_1 1348657.M622_04870 8.09e-166 483.0 COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KUQJ@206389|Rhodocyclales 206389|Rhodocyclales P Transport of potassium into the cell - - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans k141_21557_1 1122599.AUGR01000015_gene2685 5.86e-23 97.8 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_21557_2 1278309.KB907105_gene1418 1.17e-104 318.0 COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria,1XKDC@135619|Oceanospirillales 135619|Oceanospirillales S protein related to plant photosystem II stability - - - - - - - - - - - - PSII_BNR k141_4828_1 2340.JV46_05560 1.67e-153 441.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1J4WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_16633_1 1121935.AQXX01000143_gene4135 1.74e-85 254.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,1S63W@1236|Gammaproteobacteria,1XMRJ@135619|Oceanospirillales 135619|Oceanospirillales S Cupin domain - - - - - - - - - - - - Cupin_2 k141_16633_2 1121428.DESHY_10115___1 1.37e-12 73.6 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,260GE@186807|Peptococcaceae 186801|Clostridia H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_16633_3 1280946.HY29_01935 6.62e-38 132.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2VANF@28211|Alphaproteobacteria,440HP@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_16633_4 32057.KB217478_gene7415 1.52e-72 227.0 COG0500@1|root,COG0500@2|Bacteria,1G4D6@1117|Cyanobacteria,1HNTN@1161|Nostocales 1117|Cyanobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_31 k141_16633_5 1238450.VIBNISOn1_900017 2.94e-89 266.0 2CCI4@1|root,30BPJ@2|Bacteria,1RE42@1224|Proteobacteria,1S47G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15989_1 555778.Hneap_1403 3.57e-48 164.0 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,1WXZX@135613|Chromatiales 135613|Chromatiales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_7575_2 160799.PBOR_25155 4.89e-35 123.0 COG2329@1|root,COG2329@2|Bacteria,1VAM1@1239|Firmicutes,4HJD7@91061|Bacilli,26YVP@186822|Paenibacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase yqjZ - - - - - - - - - - - ABM k141_22230_1 1288826.MSNKSG1_01028 1.12e-144 422.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_22230_2 1288826.MSNKSG1_01023 4.81e-243 675.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,4640Q@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_8354_1 56780.SYN_02218 1.75e-98 312.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_18754_1 641112.ACOK01000055_gene3805 1.9e-11 67.8 COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,3WIGF@541000|Ruminococcaceae 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF218 k141_18754_2 977880.RALTA_A1406 3.67e-07 51.2 COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,2VKVW@28216|Betaproteobacteria,1K3JQ@119060|Burkholderiaceae 28216|Betaproteobacteria M MltA-interacting protein MipA - - - - - - - - - - - - MipA k141_620_1 1280001.BAOA01000100_gene4462 8.45e-14 73.6 COG1262@1|root,COG1262@2|Bacteria,1PDSD@1224|Proteobacteria,1S4ZV@1236|Gammaproteobacteria,1XVWH@135623|Vibrionales 135623|Vibrionales S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase k141_8928_1 265072.Mfla_1031 1.62e-160 489.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales 206350|Nitrosomonadales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_10392_1 1049564.TevJSym_bt00140 2.07e-101 311.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1J51V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c45100 ThiC-associated,ThiC_Rad_SAM k141_2689_1 1278309.KB907100_gene2323 4.76e-09 55.8 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1XK0E@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component gtrA - - - - - - - - - - - DctQ k141_2689_2 1278309.KB907100_gene2322 1.31e-290 798.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHXR@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM k141_2689_3 1278309.KB907100_gene2320 1.17e-247 682.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XH97@135619|Oceanospirillales 135619|Oceanospirillales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_2689_4 1278309.KB907100_gene2319 2.66e-188 526.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,1XJ1F@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_2689_5 1278309.KB907100_gene2318 1.52e-15 70.9 2EQ5G@1|root,33HRT@2|Bacteria,1NKCG@1224|Proteobacteria,1SIHD@1236|Gammaproteobacteria,1XQUX@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_2689_6 1278309.KB907100_gene2317 1.93e-291 800.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XH9N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_13899_2 1167006.UWK_00497 1.57e-32 122.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria 1224|Proteobacteria E Spermidine synthase speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth k141_12536_1 765911.Thivi_0366 2.18e-26 103.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1WYIG@135613|Chromatiales 135613|Chromatiales N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C k141_12536_2 765914.ThisiDRAFT_0156 4.15e-148 427.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1WWMX@135613|Chromatiales 135613|Chromatiales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_12536_3 1452718.JBOY01000068_gene1338 1e-12 70.1 COG1580@1|root,COG1580@2|Bacteria,1N2N9@1224|Proteobacteria,1SAF0@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_12536_4 754476.Q7A_659 8.72e-92 272.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,460FA@72273|Thiotrichales 72273|Thiotrichales L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn - - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_12536_5 1123514.KB905899_gene580 2.13e-16 80.9 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales 72273|Thiotrichales O PFAM Peptidase family M48 - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_10393_1 667014.Thein_1221 3.04e-20 93.2 COG3267@1|root,COG3267@2|Bacteria,2GIEX@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria U Pfam:Arch_ATPase - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 k141_2707_1 391615.ABSJ01000043_gene2313 3.01e-93 282.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1J4DJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_2707_2 1439940.BAY1663_01253 2.03e-58 192.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_6803_1 367336.OM2255_06590 3e-126 391.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC k141_16646_1 1278309.KB907100_gene1908 2.74e-170 479.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XHYC@135619|Oceanospirillales 135619|Oceanospirillales L recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_16646_2 1278309.KB907100_gene1907 9.03e-135 386.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XJNT@135619|Oceanospirillales 135619|Oceanospirillales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_16646_3 1278309.KB907100_gene1906 3.16e-282 776.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1XHWG@135619|Oceanospirillales 135619|Oceanospirillales E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_16646_4 1278309.KB907100_gene1905 0.0 882.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1XHQ2@135619|Oceanospirillales 135619|Oceanospirillales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N k141_16646_5 1278309.KB907100_gene1904 2.17e-159 450.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria 1224|Proteobacteria S PFAM DUF218 domain ycbC GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - - - - - - - - - - DUF218 k141_16646_6 1278309.KB907100_gene1903 1.79e-254 709.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1XI04@135619|Oceanospirillales 135619|Oceanospirillales L exonuclease recJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_11132_1 1288826.MSNKSG1_15991 7.4e-114 330.0 COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,1RXZH@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_11132_2 1288826.MSNKSG1_15996 1.17e-140 401.0 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1RR86@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid apbA - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_1384_1 743299.Acife_2202 8.65e-29 112.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,2NCEX@225057|Acidithiobacillales 225057|Acidithiobacillales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_1384_2 1298593.TOL_1531 7.28e-173 490.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XHYW@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_20034_1 398580.Dshi_2537 1.12e-91 277.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria 28211|Alphaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - - k141_11756_1 34506.g2380 9.37e-66 228.0 COG0324@1|root,COG0330@1|root,COG2262@1|root,KOG0410@2759|Eukaryota,KOG1384@2759|Eukaryota,KOG2621@2759|Eukaryota,39RQC@33154|Opisthokonta,3BCJP@33208|Metazoa,3CY54@33213|Bilateria,40AR7@6231|Nematoda,1KV6T@119089|Chromadorea,40W7R@6236|Rhabditida 33208|Metazoa J Belongs to the IPP transferase family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0007275,GO:0007568,GO:0008033,GO:0008150,GO:0008152,GO:0008340,GO:0009451,GO:0009987,GO:0010259,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0032501,GO:0032502,GO:0034470,GO:0034641,GO:0034660,GO:0040008,GO:0040014,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048638,GO:0048856,GO:0050789,GO:0050793,GO:0051239,GO:0052381,GO:0065007,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT,zf-met k141_11756_2 1249627.D779_0211 3.23e-32 124.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales 135613|Chromatiales O HflC and HflK could encode or regulate a protease - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_661_2 1246995.AFR_26665 3.17e-28 109.0 COG2329@1|root,COG2329@2|Bacteria,2GTB1@201174|Actinobacteria,4DETI@85008|Micromonosporales 201174|Actinobacteria S Domain of unknown function (DUF3291) - - - - - - - - - - - - DUF3291 k141_20059_1 1054213.HMPREF9946_02254 2.42e-91 287.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,2JVWB@204441|Rhodospirillales 204441|Rhodospirillales G Malonyl-CoA decarboxylase N-terminal domain - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_20832_1 765911.Thivi_3494 1.61e-193 567.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales 135613|Chromatiales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_8989_2 339670.Bamb_0616 1.65e-63 213.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,1K3VG@119060|Burkholderiaceae 28216|Betaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_5565_1 1288826.MSNKSG1_08673 3.04e-164 476.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_16678_1 2340.JV46_14180 1.1e-139 445.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T (GGDEF) domain - - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3 k141_17368_1 1123247.AUIJ01000003_gene2037 2.25e-87 266.0 COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,2TT9Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_17368_2 266809.PM03_03535 4.78e-49 166.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2TSXN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane MA20_17625 - - - - - - - - - - - Urate_ox_N k141_11757_1 1123487.KB892867_gene1096 1.49e-08 52.8 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales 206389|Rhodocyclales J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k141_11757_2 357804.Ping_2217 4.36e-21 85.5 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,2QIDF@267894|Psychromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_20060_1 351016.RAZWK3B_15563 1.77e-95 298.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2P100@2433|Roseobacter 28211|Alphaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_20833_1 2340.JV46_27150 5.27e-81 248.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1J4SJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0035 DapB_C,DapB_N k141_2031_1 1122194.AUHU01000009_gene3165 1.15e-83 271.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_15209_1 1026882.MAMP_01752 9.44e-32 115.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,461DR@72273|Thiotrichales 72273|Thiotrichales G PTS system fructose - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man k141_15209_2 323261.Noc_2797 1.84e-61 197.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales 135613|Chromatiales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_662_1 1288826.MSNKSG1_03817 2.66e-214 627.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k141_20834_1 627192.SLG_27640 3.94e-52 185.0 COG4774@1|root,COG4774@2|Bacteria,1NSA5@1224|Proteobacteria,2UNVI@28211|Alphaproteobacteria,2K93P@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18794_1 391626.OAN307_c25790 2.06e-82 253.0 COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,2U2CW@28211|Alphaproteobacteria 28211|Alphaproteobacteria K helix_turn _helix lactose operon repressor rbtR - - ko:K02529,ko:K03435 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_4 k141_20061_1 398579.Spea_1870 2.44e-72 228.0 2CC9X@1|root,32RV5@2|Bacteria,1N9V4@1224|Proteobacteria,1TJ9T@1236|Gammaproteobacteria,2QDQE@267890|Shewanellaceae 1236|Gammaproteobacteria S Restriction endonuclease - - - - - - - - - - - - Mrr_cat k141_16679_1 377629.TERTU_1670 1.81e-94 281.0 COG0811@1|root,COG0811@2|Bacteria,1MUNJ@1224|Proteobacteria,1RZ2K@1236|Gammaproteobacteria,2PQB3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB k141_2738_1 1121878.AUGL01000005_gene2729 5.18e-127 374.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - iSDY_1059.SDY_4251 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_2738_2 754477.Q7C_897 2.67e-90 280.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales 72273|Thiotrichales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_17369_1 187272.Mlg_2079 1.5e-137 409.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_21594_1 1278309.KB907109_gene3266 6.51e-312 858.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1XIW2@135619|Oceanospirillales 135619|Oceanospirillales S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_21594_2 1278309.KB907109_gene3267 0.0 1304.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1XIQW@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_21594_3 1278309.KB907109_gene3268 6.55e-82 248.0 COG0457@1|root,COG0457@2|Bacteria,1N3T7@1224|Proteobacteria,1SFI0@1236|Gammaproteobacteria,1XRTF@135619|Oceanospirillales 135619|Oceanospirillales S Tetratricopeptide repeat - - - - - - - - - - - - - k141_21594_4 1278309.KB907109_gene3269 2.56e-41 140.0 2C0CP@1|root,32SP5@2|Bacteria,1N5DU@1224|Proteobacteria,1SJ9A@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21594_5 1278309.KB907109_gene3270 2.11e-91 268.0 COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria,1XKAN@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c - - - ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 - - Cytochrom_C k141_21594_6 1278309.KB907109_gene3271 0.0 869.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1XIMZ@135619|Oceanospirillales 135619|Oceanospirillales P Cytochrome C and Quinol oxidase polypeptide I - - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_21594_7 1278309.KB907109_gene3272 6.8e-182 511.0 COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_5 k141_21594_8 1278309.KB907109_gene3273 5.87e-90 269.0 COG1845@1|root,COG1845@2|Bacteria,1RG3S@1224|Proteobacteria,1S75W@1236|Gammaproteobacteria,1XPFK@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c oxidase subunit III - - - - - - - - - - - - COX3 k141_21594_10 1278309.KB907109_gene3275 9.16e-176 492.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1XHPX@135619|Oceanospirillales 135619|Oceanospirillales S CbbQ/NirQ/NorQ C-terminal - - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_20835_1 754476.Q7A_2613 7.34e-115 336.0 COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,1RP48@1236|Gammaproteobacteria,45ZPE@72273|Thiotrichales 72273|Thiotrichales L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 k141_6225_1 225937.HP15_2910 1.1e-254 698.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,46402@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0191 Fructose tagatose bisphosphate aldolase fba - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_4960 F_bP_aldolase k141_6225_2 1288826.MSNKSG1_10733 1.21e-265 729.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,464NK@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the phosphoglycerate kinase family pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSbBS512_1146.SbBS512_E3351 PGK k141_2032_1 1278309.KB907101_gene385 4.5e-122 365.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XIQU@135619|Oceanospirillales 135619|Oceanospirillales T Chemotaxis sensory transducer family protein - - - - - - - - - - - - GAF,GAF_2,HD,HD_5 k141_11759_1 713586.KB900536_gene3006 1.64e-48 164.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales 135613|Chromatiales Q PFAM methyltransferase - - - - - - - - - - - - Methyltransf_11 k141_11759_2 644283.Micau_3282 3.59e-13 66.2 COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4DDG3@85008|Micromonosporales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_7629_1 1278309.KB907105_gene1458 0.0 1204.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales 135619|Oceanospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_15211_1 1236542.BALM01000001_gene75 1.39e-57 181.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,2QBKB@267890|Shewanellaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - iE2348C_1286.E2348C_3156,iPC815.YPO0906 GCV_H k141_663_1 1041139.KB902691_gene1034 3.46e-23 97.1 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2VG2Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Type II secretion system (T2SS), protein F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_663_2 1287276.X752_14645 3.02e-32 127.0 COG2064@1|root,COG2064@2|Bacteria,1RK6W@1224|Proteobacteria,2U9VM@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU type II secretion - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_20836_1 225937.HP15_3649 3.12e-141 424.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,465IY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_7630_1 413404.Rmag_0812 7.11e-05 43.1 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1JATU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_21595_2 314278.NB231_01329 3.25e-20 90.1 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1X2GE@135613|Chromatiales 135613|Chromatiales M Belongs to the skp family - - - ko:K06142 - - - - ko00000 - - - OmpH k141_21595_3 1122599.AUGR01000001_gene434 4.62e-11 63.5 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XHAS@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_11760_1 748449.Halha_0492 6.56e-06 52.4 COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,3WACM@53433|Halanaerobiales 186801|Clostridia M PFAM Copper amine oxidase N-terminal domain lytC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,Cu_amine_oxidN1 k141_11760_2 314292.VAS14_18844 1.82e-24 102.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales 135623|Vibrionales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_16681_1 519989.ECTPHS_04074 3.97e-68 216.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales 135613|Chromatiales H Belongs to the ribF family - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_16681_2 1335757.SPICUR_07520 9.34e-47 167.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales 135613|Chromatiales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k141_2059_3 1273125.Rrhod_1877 1.59e-24 95.1 COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria,4G2JC@85025|Nocardiaceae 201174|Actinobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 k141_692_1 1449351.RISW2_01960 1.2e-65 209.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_18812_1 1232683.ADIMK_0925 1.36e-57 184.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,465MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1126 ABC-type polar amino acid transport system, ATPase component yhdZ GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 ko:K02028,ko:K02029,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - iJN746.PP_1300 ABC_tran k141_19504_1 1123518.ARWI01000001_gene1337 1.17e-88 270.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales 72273|Thiotrichales S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_14565_1 1288826.MSNKSG1_13722 7.39e-237 653.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RN38@1236|Gammaproteobacteria,46BGS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 phbC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_14565_2 1288826.MSNKSG1_13717 5.17e-218 601.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,464NS@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase yihG - - - - - - - - - - - Acyltransferase k141_14565_3 1479237.JMLY01000001_gene402 1.66e-37 126.0 2DRZ6@1|root,33DSR@2|Bacteria,1NKAG@1224|Proteobacteria,1SHPA@1236|Gammaproteobacteria,4699D@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14565_4 1288826.MSNKSG1_13707 0.0 1245.0 COG0557@1|root,COG0557@2|Bacteria,1R33Q@1224|Proteobacteria,1T62R@1236|Gammaproteobacteria,464BW@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the RNR ribonuclease family - - 3.1.13.1 ko:K01147,ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_14565_5 1288826.MSNKSG1_13702 3.03e-155 436.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,465A3@72275|Alteromonadaceae 1236|Gammaproteobacteria S PKHD-type hydroxylase ybiX - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 k141_14565_6 1288826.MSNKSG1_13697 3.6e-19 85.9 COG5497@1|root,COG5497@2|Bacteria,1QXG7@1224|Proteobacteria 1224|Proteobacteria S secreted protein - - - - - - - - - - - - - k141_11779_1 1397528.Q671_09195 1.43e-16 78.2 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XIZ0@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_11779_2 1278309.KB907102_gene169 7.14e-177 504.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XIUD@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamate synthase family - - 2.1.1.21 ko:K22083 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - Glu_synthase,zf-CDGSH k141_16707_1 998674.ATTE01000001_gene2757 2.93e-85 273.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales 72273|Thiotrichales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_2772_1 342610.Patl_1599 6.64e-13 65.9 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,2Q2AE@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB k141_2772_3 395494.Galf_1153 4.17e-12 72.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WBI@713636|Nitrosomonadales 28216|Betaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - - - - - - - - - - EAL,GGDEF,PAS_9,Phosphonate-bd k141_693_1 384765.SIAM614_23297 8.88e-94 288.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,2TVXR@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_4052_1 243233.MCA1475 2.02e-139 415.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales 135618|Methylococcales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_17406_2 998088.B565_3980 7.77e-27 105.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1Y3GC@135624|Aeromonadales 135624|Aeromonadales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_14566_1 857087.Metme_2662 1.41e-14 70.5 COG0454@1|root,COG0456@2|Bacteria,1N538@1224|Proteobacteria,1S8WA@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 k141_14566_2 396588.Tgr7_0591 1.18e-52 168.0 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1X2HD@135613|Chromatiales 135613|Chromatiales S MazG-like family - - - - - - - - - - - - MazG-like k141_9035_1 675812.VHA_001827 1.85e-97 315.0 COG2199@1|root,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1Y2GK@135623|Vibrionales 135623|Vibrionales T Hpt domain - - - - - - - - - - - - GGDEF,Hpt,Response_reg k141_2060_1 1279017.AQYJ01000027_gene1702 2.51e-07 52.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,464C7@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_2060_2 1193181.BN10_540069 8.71e-08 51.2 COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4FHWG@85021|Intrasporangiaceae 201174|Actinobacteria P Copper chaperone - - - - - - - - - - - - HMA k141_2060_3 1249627.D779_0312 1.22e-52 176.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales 135613|Chromatiales M Arabinose 5-phosphate isomerase - - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_6833_1 1168065.DOK_14704 2.82e-116 339.0 COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,1RRMA@1236|Gammaproteobacteria,1J4ZM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Transglutaminase/protease-like homologues - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_17407_1 1188256.BASI01000001_gene1433 9.69e-07 55.8 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,3FDT9@34008|Rhodovulum 28211|Alphaproteobacteria EQ Hydantoinase B/oxoprolinase oplaH - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_2773_1 1454004.AW11_02049 9.85e-22 100.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,1KR45@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Coenzyme metabolism hemY - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_12 k141_20215_2 265072.Mfla_2534 1.15e-61 214.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,2KKGH@206350|Nitrosomonadales 206350|Nitrosomonadales MU TIGRFAM type I secretion outer membrane protein, TolC family - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_20215_3 1278309.KB907108_gene1551 0.0 1444.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XH6K@135619|Oceanospirillales 135619|Oceanospirillales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_19526_1 270374.MELB17_21770 1.35e-143 417.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_15341_1 452637.Oter_0836 2.69e-56 184.0 COG4912@1|root,COG4912@2|Bacteria,46VM8@74201|Verrucomicrobia 74201|Verrucomicrobia L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation k141_15341_2 595537.Varpa_4218 1.26e-34 120.0 COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,2VU8K@28216|Betaproteobacteria,4AEWH@80864|Comamonadaceae 28216|Betaproteobacteria S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 k141_2100_1 472759.Nhal_1619 5.74e-94 300.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1X01G@135613|Chromatiales 135613|Chromatiales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_21610_1 765912.Thimo_2635 9.86e-25 100.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_21610_2 748658.KB907313_gene2052 3.74e-18 82.4 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_21610_3 95619.PM1_0218345 8.19e-57 191.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_3490_1 1163617.SCD_n00142 1.46e-106 319.0 COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2VI3X@28216|Betaproteobacteria 28216|Betaproteobacteria EGP Major Facilitator - - - - - - - - - - - - MFS_1 k141_11160_1 498211.CJA_1764 3.34e-69 237.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1FGID@10|Cellvibrio 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_18826_1 765910.MARPU_03215 5.29e-72 230.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1WX5T@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_18826_2 1396858.Q666_12485 1.12e-82 254.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,46407@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yciK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short k141_17429_1 237368.SCABRO_01929 2.93e-82 258.0 COG0025@1|root,COG0025@2|Bacteria,2IZBZ@203682|Planctomycetes 203682|Planctomycetes P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_5580_1 1288826.MSNKSG1_14162 1.27e-178 501.0 COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,1SBT6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent) - - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans k141_16736_1 765914.ThisiDRAFT_1262 5.91e-41 152.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WWUD@135613|Chromatiales 135613|Chromatiales NU general secretion pathway protein D - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_7678_1 1288826.MSNKSG1_18480 1.62e-237 656.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU pilus assembly protein PilW pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_7678_2 1288826.MSNKSG1_18485 5.28e-91 268.0 COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria,1SGXT@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Pilus assembly protein PilX - - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX_N k141_7678_4 1288826.MSNKSG1_18495 3.78e-61 209.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 k141_11857_1 1121015.N789_14330 8.49e-14 76.6 COG0845@1|root,COG0845@2|Bacteria,1QTZQ@1224|Proteobacteria,1T1J7@1236|Gammaproteobacteria,1XCQC@135614|Xanthomonadales 135614|Xanthomonadales M Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_12553_1 1278309.KB907104_gene886 4.88e-219 609.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XHRY@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12553_2 1278309.KB907104_gene885 5.87e-22 92.8 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XI08@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_3491_1 159450.NH14_02450 1.01e-75 230.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,1K5JG@119060|Burkholderiaceae 28216|Betaproteobacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP k141_13253_1 1278309.KB907110_gene3221 2e-127 363.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XJAY@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the sigma-70 factor family. ECF subfamily algU - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_13253_2 1278309.KB907110_gene3220 3.95e-136 392.0 COG3073@1|root,COG3073@2|Bacteria,1QSS4@1224|Proteobacteria,1RWAH@1236|Gammaproteobacteria,1XK8N@135619|Oceanospirillales 135619|Oceanospirillales T MucB/RseB C-terminal domain - - - - - - - - - - - - MucB_RseB_C,RseA_N k141_20217_1 1278308.KB907080_gene2410 2.9e-23 102.0 COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4FM9P@85023|Microbacteriaceae 201174|Actinobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3,Phospholip_A2_3 k141_704_1 1188256.BASI01000002_gene3147 8.9e-20 89.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,3FD3E@34008|Rhodovulum 28211|Alphaproteobacteria S Peptidase family M48 MA20_29180 - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_19 k141_704_2 999549.KI421513_gene3057 1.67e-48 163.0 COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,280JW@191028|Leisingera 28211|Alphaproteobacteria O Thioredoxin - - - - - - - - - - - - DSBA,Thioredoxin_4 k141_16738_1 595494.Tola_1338 1.2e-40 147.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1Y6GF@135624|Aeromonadales 135624|Aeromonadales P TOBE domain - - - ko:K10191 ko02010,map02010 M00199 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.4 - - ABC_tran,TOBE_2 k141_3509_1 1453501.JELR01000001_gene2680 2.28e-59 210.0 COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,4650J@72275|Alteromonadaceae 1236|Gammaproteobacteria T response regulator rsbU - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_5600_3 4155.Migut.G00885.1.p 5.16e-133 377.0 KOG1721@1|root,KOG1721@2759|Eukaryota,38A9Z@33090|Viridiplantae,3GY91@35493|Streptophyta,44UXV@71274|asterids 35493|Streptophyta S DNA binding - - - - - - - - - - - - - k141_5600_4 3847.GLYMA13G11980.1 3.54e-81 271.0 2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids 35493|Streptophyta - - - - - - - - - - - - - - - k141_5600_5 4641.GSMUA_AchrUn_randomP22450_001 1.04e-22 95.1 2E6PU@1|root,2SDCQ@2759|Eukaryota,382FA@33090|Viridiplantae,3GR3G@35493|Streptophyta 35493|Streptophyta - - - - - - - - - - - - - - - k141_5600_6 225117.XP_009366572.1 3.05e-20 89.0 2CV7H@1|root,2RRGK@2759|Eukaryota,383A9@33090|Viridiplantae,3GS0R@35493|Streptophyta 35493|Streptophyta - - - - - - - - - - - - - - - k141_20939_1 2340.JV46_18410 4.2e-36 127.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1J6GH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200 - - - - ko00000 - - - CcmH,TPR_19 k141_20939_2 2340.JV46_18400 9.81e-15 70.9 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1J5YJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CO Redoxin dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_21627_2 1219065.VPR01S_01_02990 2.06e-206 583.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XWB0@135623|Vibrionales 135623|Vibrionales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,MscS_TM k141_21627_3 1121374.KB891586_gene2742 2.6e-246 681.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RRS7@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - RimK,TrkA_C k141_21627_4 1278309.KB907102_gene166 3.24e-81 246.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria,1XJJP@135619|Oceanospirillales 135619|Oceanospirillales S Haloacid dehalogenase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_7002_1 1009370.ALO_21896 3.27e-133 405.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4H28M@909932|Negativicutes 909932|Negativicutes KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_7002_2 1177179.A11A3_04590 3.09e-10 62.8 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1XMTM@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_18851_1 906968.Trebr_1534 0.000135 46.2 COG1716@1|root,COG1716@2|Bacteria,2J7PU@203691|Spirochaetes 203691|Spirochaetes T COGs COG1716 FOG FHA domain - - - - - - - - - - - - FHA k141_15364_1 1278309.KB907099_gene2972 1.58e-35 121.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales 135619|Oceanospirillales K cold-shock protein cspG - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_15364_2 472759.Nhal_2898 3.93e-45 154.0 COG2890@1|root,COG2890@2|Bacteria,1QVSR@1224|Proteobacteria,1T2R8@1236|Gammaproteobacteria,1X2NM@135613|Chromatiales 135613|Chromatiales J Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_16758_1 269799.Gmet_2351 9.04e-95 287.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family gnnB - - - - - - - - - - iAF987.Gmet_2351 DegT_DnrJ_EryC1 k141_16758_2 269799.Gmet_2352 2.49e-137 398.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C k141_16758_3 1149133.ppKF707_0698 4.42e-89 267.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1YE1X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_16758_4 1469245.JFBG01000011_gene834 1.02e-59 190.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales 135613|Chromatiales L PFAM HNH endonuclease - - - - - - - - - - - - HNH_5 k141_11881_1 998674.ATTE01000001_gene3662 2.72e-95 287.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales 72273|Thiotrichales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_10474_1 391615.ABSJ01000059_gene2143 4.47e-56 182.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1J6KR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_10474_2 1124982.MSI_03260 1.54e-06 48.9 COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes 203691|Spirochaetes O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_4202_2 580332.Slit_1717 1.83e-104 303.0 COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,2W324@28216|Betaproteobacteria 28216|Betaproteobacteria O Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - - k141_4202_3 580332.Slit_1718 2.32e-58 199.0 COG0457@1|root,COG0457@2|Bacteria,1R4NF@1224|Proteobacteria 1224|Proteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_10,cNMP_binding k141_20247_2 1122603.ATVI01000009_gene2612 1.11e-27 103.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif - - - - - - - - - - - - RRM_1 k141_12573_1 1188256.BASI01000002_gene3330 1.59e-87 268.0 COG1262@1|root,COG1262@2|Bacteria,1R59H@1224|Proteobacteria,2U375@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase k141_18852_1 519441.Smon_1402 5.9e-08 54.7 COG0596@1|root,COG0596@2|Bacteria,3798W@32066|Fusobacteria 32066|Fusobacteria S Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_7003_1 395493.BegalDRAFT_2883 4.23e-52 185.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales 72273|Thiotrichales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_21628_1 1288963.ADIS_4011 3.06e-43 154.0 COG1331@1|root,COG1331@2|Bacteria,4NIPN@976|Bacteroidetes 976|Bacteroidetes O Highly conserved protein containing a thioredoxin domain - - - - - - - - - - - - Glyco_hydro_88 k141_18142_1 102129.Lepto7375DRAFT_0197 1.13e-99 302.0 COG1680@1|root,COG1680@2|Bacteria 2|Bacteria V peptidase activity - - - - - - - - - - - - Beta-lactamase k141_7699_1 28258.KP05_01155 4.3e-115 345.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase - - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_7699_2 570417.WP0358 1.15e-27 113.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,47F0K@766|Rickettsiales 766|Rickettsiales T response regulator containing a CheY-like receiver domain and a GGDEF domain pleD - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg k141_7699_3 1249634.D781_0605 3.07e-05 48.9 COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,400TX@613|Serratia 1236|Gammaproteobacteria S bacterial OsmY and nodulation domain osmY GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - ko:K04065 - - - - ko00000 - - - BON k141_7699_4 1415779.JOMH01000001_gene2821 2.58e-99 299.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1X5G3@135614|Xanthomonadales 135614|Xanthomonadales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_733_1 857087.Metme_4570 2.84e-66 206.0 COG1433@1|root,COG1433@2|Bacteria,1N05Z@1224|Proteobacteria,1SB2E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Dinitrogenase iron-molybdenum cofactor - - - ko:K02596 - - - - ko00000 - - - Nitro_FeMo-Co k141_733_2 519989.ECTPHS_12338 1.04e-54 178.0 COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,1WYXY@135613|Chromatiales 135613|Chromatiales C Low-potential electron donor to a number of redox enzymes - - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 k141_8393_1 1348657.M622_04870 2.16e-83 265.0 COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KUQJ@206389|Rhodocyclales 206389|Rhodocyclales P Transport of potassium into the cell - - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans k141_8393_2 1469607.KK073768_gene1213 8.99e-30 120.0 COG2199@1|root,COG3706@2|Bacteria,1G2YJ@1117|Cyanobacteria,1HJR0@1161|Nostocales 1117|Cyanobacteria T TIGRFAM diguanylate cyclase (GGDEF) domain - - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF k141_6291_1 1122599.AUGR01000014_gene590 1.91e-56 189.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIY5@135619|Oceanospirillales 135619|Oceanospirillales C Glycolate oxidase subunit GlcD glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_6291_2 1535422.ND16A_0783 4.16e-75 227.0 COG3193@1|root,COG3193@2|Bacteria,1RB2H@1224|Proteobacteria,1S5K1@1236|Gammaproteobacteria,2Q6T5@267889|Colwelliaceae 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_2114_1 1288826.MSNKSG1_11953 9.82e-144 424.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria,465B0@72275|Alteromonadaceae 1236|Gammaproteobacteria CK Regulator of nitric oxide reductase transcription yccM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19339 - - - - ko00000,ko03000 - - - FMN_bind,Fer4,Fer4_5 k141_2114_2 1288826.MSNKSG1_11962 4.93e-315 860.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465NN@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family aldB - 1.2.1.3 ko:K00128,ko:K00138 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_20248_1 1278309.KB907103_gene1006 2.7e-92 273.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XJI5@135619|Oceanospirillales 135619|Oceanospirillales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_1417_2 1278309.KB907105_gene1460 3.65e-171 481.0 COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,1RYBB@1236|Gammaproteobacteria,1XQWP@135619|Oceanospirillales 135619|Oceanospirillales I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_1417_3 1278309.KB907105_gene1461 1.01e-96 289.0 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,1XHZP@135619|Oceanospirillales 135619|Oceanospirillales S COG4240 Predicted kinase - - 2.7.1.31 ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ArgK,PRK k141_9082_1 371731.Rsw2DRAFT_2226 9.95e-83 270.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,1FBFS@1060|Rhodobacter 28211|Alphaproteobacteria S Tetratricopeptide repeat MA20_42300 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_3510_1 1049564.TevJSym_bm00060 2.4e-79 253.0 COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,1RY3G@1236|Gammaproteobacteria,1J6JD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF898) yjgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF898 k141_15366_1 521719.ATXQ01000001_gene318 1.95e-78 246.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RWYE@1236|Gammaproteobacteria,1YJXE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_11185_1 1249627.D779_4120 9.78e-67 216.0 COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,1WZ29@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF599 - - - - - - - - - - - - DUF599 k141_11185_2 765912.Thimo_0821 2.6e-06 53.9 COG0790@1|root,COG0790@2|Bacteria,1QCXZ@1224|Proteobacteria,1TKB7@1236|Gammaproteobacteria,1X1ES@135613|Chromatiales 135613|Chromatiales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_7700_1 670307.HYPDE_24643 6.38e-81 256.0 COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,3N6KS@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04566 ko00970,map00970 M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1f k141_21629_1 1121352.JHZP01000008_gene1862 1.15e-24 100.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,2KRTN@206351|Neisseriales 206351|Neisseriales NU Pilin (bacterial filament) - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_1568_1 1177181.T9A_01739 5.39e-59 197.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XH2C@135619|Oceanospirillales 135619|Oceanospirillales M mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_19698_1 1121943.KB899990_gene3822 9e-06 48.5 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1XHN0@135619|Oceanospirillales 135619|Oceanospirillales P COG3639 ABC-type phosphate phosphonate transport system, permease component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - - k141_19698_2 1278309.KB907108_gene1629 1.72e-109 320.0 COG3638@1|root,COG3638@2|Bacteria,1RF8E@1224|Proteobacteria,1S3VW@1236|Gammaproteobacteria,1XJTH@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter, ATP-binding protein - - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k141_867_1 2340.JV46_07050 8.65e-81 245.0 COG1814@1|root,COG1814@2|Bacteria,1RBQN@1224|Proteobacteria,1S2ZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - - k141_867_2 1122599.AUGR01000021_gene3198 2.75e-27 102.0 COG1888@1|root,COG1888@2|Bacteria,1N92Y@1224|Proteobacteria,1SD5W@1236|Gammaproteobacteria,1XQPP@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized ArCR, COG1888 - - - - - - - - - - - - DUF211 k141_18296_1 1232683.ADIMK_2107 1.08e-110 340.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,1RS0H@1236|Gammaproteobacteria,46AHH@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme fcs - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding k141_18296_2 1232683.ADIMK_2108 1.13e-233 665.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase aidB GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K09456 - - - - ko00000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_18296_3 1122201.AUAZ01000046_gene2154 3.74e-130 375.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,465Z6@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short,adh_short_C2 k141_18296_4 1122201.AUAZ01000046_gene2155 1.66e-130 376.0 COG1024@1|root,COG1024@2|Bacteria,1MWYZ@1224|Proteobacteria,1RZFU@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.155 ko:K20036 ko00920,map00920 - R10936 RC00004,RC03306,RC03307 ko00000,ko00001,ko01000 - - - ECH_1 k141_10653_1 598467.BrE312_3354 1.31e-39 146.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_12025_1 511062.GU3_00725 2.02e-12 63.9 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1Y4SJ@135624|Aeromonadales 135624|Aeromonadales S Membrane fusogenic activity - - - ko:K09806 - - - - ko00000 - - - BMFP k141_9902_1 349521.HCH_06066 2.31e-49 169.0 2DBE3@1|root,2Z8QE@2|Bacteria,1N7W6@1224|Proteobacteria,1RNWG@1236|Gammaproteobacteria,1XKWB@135619|Oceanospirillales 135619|Oceanospirillales S Porin-like glycoporin RafY - - - - - - - - - - - - Porin_8 k141_9902_2 443152.MDG893_07410 8.42e-16 76.6 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,466SF@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0524 Sugar kinases, ribokinase family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_7148_1 1266998.ATUJ01000004_gene1220 5.98e-14 72.0 COG0705@1|root,COG0705@2|Bacteria,1RA4A@1224|Proteobacteria,2U5JY@28211|Alphaproteobacteria,2PV3D@265|Paracoccus 28211|Alphaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid k141_7148_2 367336.OM2255_10875 2.27e-19 85.5 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_21146_1 1049564.TevJSym_bi00150 4.08e-29 109.0 2E4CH@1|root,32Z7Y@2|Bacteria,1NBRN@1224|Proteobacteria,1SCB9@1236|Gammaproteobacteria,1J7D3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S pilus assembly protein, PilZ - - - - - - - - - - - - PilZ k141_11367_1 1185876.BN8_02108 4.37e-16 80.1 COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47KW1@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_8 k141_11367_2 34506.g2227 1.1e-46 172.0 COG0524@1|root,COG0642@1|root,KOG0519@2759|Eukaryota,KOG2855@2759|Eukaryota 2759|Eukaryota G carbohydrate kinase activity - - - - - - - - - - - - HATPase_c,HisKA,PAS,PfkB,Response_reg k141_12725_2 754436.JCM19237_2540 1.95e-82 251.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XTQ9@135623|Vibrionales 135623|Vibrionales O stringent starvation protein A sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_12725_3 999141.GME_03667 1.18e-19 83.6 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XKFH@135619|Oceanospirillales 135619|Oceanospirillales S Stringent starvation protein B sspB - - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_4365_1 1278309.KB907101_gene671 2.32e-139 399.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XH2T@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_14838_2 1288826.MSNKSG1_16476 4.96e-246 676.0 COG1638@1|root,COG1638@2|Bacteria,1PER4@1224|Proteobacteria,1RPPJ@1236|Gammaproteobacteria,469X3@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_14838_3 1288826.MSNKSG1_16481 2.49e-120 344.0 COG2945@1|root,COG2945@2|Bacteria,1RHKR@1224|Proteobacteria,1S89T@1236|Gammaproteobacteria,46BEY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0227) - - - - - - - - - - - - UPF0227 k141_15548_1 396588.Tgr7_0377 5.34e-56 179.0 COG2143@1|root,COG2143@2|Bacteria,1N6H1@1224|Proteobacteria,1SQSZ@1236|Gammaproteobacteria,1X16R@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - - - - - - - - - - - k141_15548_2 1123392.AQWL01000006_gene594 1.87e-72 228.0 COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,2W50B@28216|Betaproteobacteria,1KS36@119069|Hydrogenophilales 119069|Hydrogenophilales S Protein of unknown function (DUF3530) - - - - - - - - - - - - DUF3530 k141_155_1 292415.Tbd_1709 1.37e-35 127.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,1KSMC@119069|Hydrogenophilales 119069|Hydrogenophilales E Histidine biosynthesis protein hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_155_2 400668.Mmwyl1_0751 2.48e-157 444.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XIEI@135619|Oceanospirillales 135619|Oceanospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_17598_1 99598.Cal7507_1577 9.09e-06 49.3 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIE5@1161|Nostocales 1117|Cyanobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_17598_2 290402.Cbei_2160 4.61e-10 64.7 COG0642@1|root,COG5000@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36EKZ@31979|Clostridiaceae 186801|Clostridia T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg,dCache_1,sCache_3_3 k141_12026_1 1278309.KB907099_gene2390 1.57e-90 268.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1XJXX@135619|Oceanospirillales 135619|Oceanospirillales S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC - 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase,Hydrolase_3 k141_3673_1 1278309.KB907105_gene1505 2.68e-228 632.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XHPA@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_3673_3 1278309.KB907105_gene1504 8.05e-273 755.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XI9V@135619|Oceanospirillales 135619|Oceanospirillales P Sodium proton antiporter - - - - - - - - - - - - CitMHS k141_3673_4 1278309.KB907105_gene1503 2.75e-96 283.0 COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,1XK44@135619|Oceanospirillales 135619|Oceanospirillales C Low-potential electron donor to a number of redox enzymes - - - ko:K03839,ko:K03840 - - - - ko00000 - - - Flavodoxin_1 k141_7149_1 1123393.KB891316_gene1786 7.68e-106 318.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,1KS2N@119069|Hydrogenophilales 119069|Hydrogenophilales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_5785_1 1123392.AQWL01000006_gene612 4.38e-77 252.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,1KSP7@119069|Hydrogenophilales 119069|Hydrogenophilales P von Willebrand factor type A domain - - - - - - - - - - - - VWA k141_1570_1 1232683.ADIMK_1363 7.62e-72 226.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,464A3@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component dctP - - - - - - - - - - - DctP k141_13436_1 697282.Mettu_4074 1.08e-77 246.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XDR3@135618|Methylococcales 135618|Methylococcales K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_156_1 1500890.JQNL01000001_gene2104 1.14e-22 102.0 COG2199@1|root,COG3706@2|Bacteria,1R33D@1224|Proteobacteria,1T62G@1236|Gammaproteobacteria,1XDHM@135614|Xanthomonadales 2|Bacteria T diguanylate cyclase yedQ GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0052621,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 ko:K21085 ko02026,map02026 - - - ko00000,ko00001,ko01000 - - iLF82_1304.LF82_2957,iSbBS512_1146.SbBS512_E1077 CHASE7,GGDEF k141_2976_1 580332.Slit_1460 2.23e-171 506.0 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W78@713636|Nitrosomonadales 28216|Betaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - - - - - - - - - - EAL,GGDEF,MHYT,PAS,PAS_9,dCache_2 k141_16193_1 1237149.C900_01796 1.41e-67 217.0 COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,47JES@768503|Cytophagia 976|Bacteroidetes E Belongs to the arginase family - - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_12027_1 279714.FuraDRAFT_1917 3.51e-51 174.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KQG4@206351|Neisseriales 206351|Neisseriales M Psort location Cytoplasmic, score 8.96 rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_9205_1 314262.MED193_05934 0.00025 42.4 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2U98M@28211|Alphaproteobacteria,2P386@2433|Roseobacter 28211|Alphaproteobacteria K Transcriptional regulator, merR family - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_9205_2 351016.RAZWK3B_07694 6.46e-69 225.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2P1U0@2433|Roseobacter 28211|Alphaproteobacteria C COG1960 Acyl-CoA dehydrogenases MA20_19860 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_17599_1 626887.J057_17940 3.93e-42 155.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_20409_1 1122599.AUGR01000014_gene536 5.96e-201 573.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1XIZU@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_20409_2 1122599.AUGR01000014_gene537 3.3e-149 425.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,1XI66@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_20409_3 1122599.AUGR01000014_gene538 3.58e-140 411.0 COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1R6YN@1224|Proteobacteria,1S0UQ@1236|Gammaproteobacteria,1XN9U@135619|Oceanospirillales 135619|Oceanospirillales T HDOD domain - - - - - - - - - - - - HDOD,Response_reg k141_20409_4 443143.GM18_2280 4.96e-69 236.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales 28221|Deltaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg k141_2248_1 1045855.DSC_08285 1.06e-95 293.0 COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria,1X5RG@135614|Xanthomonadales 135614|Xanthomonadales E Ethanolamine ammonia-lyase eutA - 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutB k141_2248_2 501479.ACNW01000087_gene3894 8.01e-17 73.2 2A5SQ@1|root,30UHY@2|Bacteria,1Q45Z@1224|Proteobacteria,2UM90@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_2248_3 89187.ISM_08160 2.08e-31 123.0 COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,2TR55@28211|Alphaproteobacteria,46PMJ@74030|Roseovarius 28211|Alphaproteobacteria P Ammonium transporter - - - - - - - - - - - - Ammonium_transp k141_1571_1 349521.HCH_02592 6.48e-67 225.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,1XN5T@135619|Oceanospirillales 135619|Oceanospirillales E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_2977_1 580332.Slit_1808 4.24e-43 153.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,44V10@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_2977_2 349124.Hhal_1107 2.06e-34 131.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1X0BN@135613|Chromatiales 135613|Chromatiales G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_18298_1 1211114.ALIP01000120_gene1019 1.77e-38 146.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1X404@135614|Xanthomonadales 135614|Xanthomonadales N Belongs to the bacterial flagellin family flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_18298_2 1209072.ALBT01000011_gene3233 9.77e-29 117.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1FGRV@10|Cellvibrio 1236|Gammaproteobacteria N Flagellar basal body rod FlgEFG protein C-terminal flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_15549_1 1122599.AUGR01000009_gene2426 7.74e-185 560.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_4366_1 1288826.MSNKSG1_14717 9.35e-246 692.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_157_1 1401065.HMPREF2130_02060 1.21e-14 77.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,3T29P@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF1732) yicC - - - - - - - - - - - DUF1732,YicC_N k141_868_2 998674.ATTE01000001_gene515 1.1e-18 83.2 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU General secretion pathway protein I gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_1584_1 1123073.KB899241_gene2174 6.29e-14 81.6 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1RNGS@1236|Gammaproteobacteria,1X47E@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 k141_16214_1 658187.LDG_9064 8.47e-107 335.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1JD5Q@118969|Legionellales 118969|Legionellales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_4382_1 1123368.AUIS01000009_gene2460 1.64e-144 424.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,2NCDY@225057|Acidithiobacillales 225057|Acidithiobacillales S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_4382_2 118163.Ple7327_0411 0.000135 47.0 COG1180@1|root,COG1180@2|Bacteria,1G268@1117|Cyanobacteria,3VJEX@52604|Pleurocapsales 1117|Cyanobacteria C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_10672_1 1423144.Gal_01516 3.07e-117 348.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,34EQ5@302485|Phaeobacter 28211|Alphaproteobacteria O OsmC-like protein MA20_16590 - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_3685_1 396588.Tgr7_2026 3.43e-92 306.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales 135613|Chromatiales D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_16919_1 1288826.MSNKSG1_02218 3.8e-51 167.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,465Z6@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short,adh_short_C2 k141_16919_2 1288826.MSNKSG1_02213 3.88e-106 320.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_8568_1 1121923.GPUN_2661 5.21e-26 104.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_8568_2 1122134.KB893650_gene123 6.5e-18 86.7 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1XHZJ@135619|Oceanospirillales 135619|Oceanospirillales T PFAM Metal-dependent phosphohydrolase, HD - - - - - - - - - - - - DUF3391,HD,HD_5 k141_2989_1 983545.Glaag_2364 1.92e-90 277.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,463ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain rpfG - - ko:K07814 - - - - ko00000,ko02022 - - - HD,Response_reg k141_2989_2 722419.PH505_aj00330 1.2e-39 141.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,2Q0CB@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_5812_1 1177181.T9A_01712 6.84e-52 178.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1XQZT@135619|Oceanospirillales 135619|Oceanospirillales PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding k141_9219_1 717774.Marme_1566 5.22e-112 328.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,1XHJQ@135619|Oceanospirillales 135619|Oceanospirillales E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_9219_2 1211817.CCAT010000047_gene2522 0.000109 45.1 COG1122@1|root,COG4720@1|root,COG1122@2|Bacteria,COG4720@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,36F82@31979|Clostridiaceae 186801|Clostridia P Psort location CytoplasmicMembrane, score - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 k141_6450_1 472759.Nhal_0338 4.82e-80 241.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales 135613|Chromatiales S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate - - 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_3 k141_6450_2 686340.Metal_0240 2.61e-16 78.6 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1XDSG@135618|Methylococcales 135618|Methylococcales M Arabinose 5-phosphate isomerase - - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_10673_1 90813.JQMT01000001_gene1014 6.28e-71 223.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,45ZSU@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_19033_1 203275.BFO_0974 7.45e-76 246.0 COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,2FMTG@200643|Bacteroidia,22W4H@171551|Porphyromonadaceae 976|Bacteroidetes G 1,4-alpha-glucan branching enzyme glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_12047_1 765912.Thimo_2330 5.05e-116 343.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_7161_1 207954.MED92_05648 2.11e-123 358.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,1XHIM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_7161_2 207954.MED92_05643 6.1e-41 143.0 28H5S@1|root,2Z7IA@2|Bacteria,1MX3X@1224|Proteobacteria,1RPVF@1236|Gammaproteobacteria,1XHVW@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1852) - - - - - - - - - - - - DUF1852 k141_17623_1 1211579.PP4_50870 5.03e-37 143.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YY01@136845|Pseudomonas putida group 1236|Gammaproteobacteria NT PFAM histidine kinase, HAMP region domain protein VPA0491 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_8569_1 157783.LK03_09640 1.53e-34 130.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria 2|Bacteria NT chemotaxis cheV3 - 2.7.13.3 ko:K03407,ko:K03408,ko:K03415,ko:K13489 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,Response_reg k141_983_6 1288826.MSNKSG1_00406 3.42e-129 368.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,468QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S to the N-terminal domain of Lon protease - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_983_7 1288826.MSNKSG1_00401 8.23e-260 715.0 COG0664@1|root,COG1639@1|root,COG0664@2|Bacteria,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,466AI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_1707_1 745411.B3C1_05312 2.43e-56 189.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1J4V6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_1707_2 1042375.AFPL01000013_gene2472 2.11e-306 837.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,465BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aminotransferase class-III - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_1707_4 1042375.AFPL01000013_gene2471 1.18e-155 445.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,46591@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family bauR - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_1707_5 1042375.AFPL01000013_gene2470 8.31e-317 868.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RSR2@1236|Gammaproteobacteria,46ABS@72275|Alteromonadaceae 1236|Gammaproteobacteria FH Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur k141_1707_6 1042375.AFPL01000013_gene2469 3.08e-13 68.6 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,46532@72275|Alteromonadaceae 1236|Gammaproteobacteria F Amidohydrolase family hydA - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_17737_1 90814.KL370892_gene2295 5.02e-58 194.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales 72273|Thiotrichales C Cysteine-rich domain - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_19787_1 1288826.MSNKSG1_15172 1.94e-106 309.0 COG0847@1|root,COG0847@2|Bacteria,1RHD8@1224|Proteobacteria,1SBBK@1236|Gammaproteobacteria,467DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - RNase_T k141_19787_2 1288826.MSNKSG1_15177 1.11e-160 449.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_19787_3 1288826.MSNKSG1_15182 3.88e-164 458.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,466N4@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_19787_4 1288826.MSNKSG1_15187 8.81e-233 642.0 COG2207@1|root,COG2207@2|Bacteria,1R5XR@1224|Proteobacteria,1S55V@1236|Gammaproteobacteria,468H3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_19787_5 1288826.MSNKSG1_15192 2.57e-219 604.0 COG1073@1|root,COG1073@2|Bacteria,1RDDD@1224|Proteobacteria,1T3BD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_19787_6 1288826.MSNKSG1_15197 0.0 1023.0 COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,46500@72275|Alteromonadaceae 1236|Gammaproteobacteria L Extracellular nuclease - - - ko:K07004 - - - - ko00000 - - - Endonuclease_1,Exo_endo_phos,LTD k141_19787_7 1288826.MSNKSG1_15202 4.26e-218 601.0 COG2378@1|root,COG2378@2|Bacteria,1Q19K@1224|Proteobacteria,1RZ1N@1236|Gammaproteobacteria,464T2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - WYL k141_19787_8 1288826.MSNKSG1_15207 2.44e-272 749.0 COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,1RP39@1236|Gammaproteobacteria,46791@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3,Sugar_tr k141_19787_9 1288826.MSNKSG1_15212 2.21e-92 270.0 COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1SB3V@1236|Gammaproteobacteria,468P7@72275|Alteromonadaceae 1236|Gammaproteobacteria K B-block binding subunit of TFIIIC - - - ko:K06075 - - - - ko00000,ko03000 - - - MarR k141_19787_10 1288826.MSNKSG1_15217 1.83e-138 401.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,46CFS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0477 Permeases of the major facilitator superfamily - - - ko:K08170 - M00702 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 - - MFS_1 k141_20556_1 1288826.MSNKSG1_02961 9.49e-113 331.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,46AHI@72275|Alteromonadaceae 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_20556_2 1288826.MSNKSG1_02956 1.26e-241 664.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,467CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_20556_3 1288826.MSNKSG1_02951 7.99e-163 459.0 2EGPT@1|root,33AFY@2|Bacteria,1NGQG@1224|Proteobacteria,1SHME@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18415_1 1000565.METUNv1_01984 8.86e-114 342.0 COG3203@1|root,COG3203@2|Bacteria,1N1KC@1224|Proteobacteria,2VKGE@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM porin Gram-negative type - - - - - - - - - - - - Porin_4 k141_2355_1 866536.Belba_0882 2.89e-73 244.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia 976|Bacteroidetes L PFAM Helicase conserved C-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N k141_11454_3 1238182.C882_2978 1.6e-06 51.6 COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2TXIK@28211|Alphaproteobacteria,2JTDH@204441|Rhodospirillales 204441|Rhodospirillales J COG1544 Ribosome-associated protein Y (PSrp-1) - - - - - - - - - - - - Ribosomal_S30AE k141_17738_2 713586.KB900536_gene2298 4.28e-51 172.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_284_1 1249627.D779_4117 1.76e-93 288.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWGD@135613|Chromatiales 135613|Chromatiales T response regulator - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_284_2 2340.JV46_13870 4.32e-60 189.0 2DZRC@1|root,32VGV@2|Bacteria,1N2PT@1224|Proteobacteria,1SQQ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Cytochrom_C_2 k141_12867_2 1049564.TevJSym_ab00680 1.45e-35 128.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1J4EP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_12165_1 587753.EY04_02195 2.1e-21 99.0 COG0840@1|root,COG0840@2|Bacteria,1RFH2@1224|Proteobacteria,1SMC2@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_305_1 472759.Nhal_0023 1.2e-29 116.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_9325_2 331869.BAL199_23257 1.28e-08 60.8 COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,4BRN6@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 k141_15641_1 1122137.AQXF01000007_gene3477 2.19e-44 146.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,2UC11@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_03865 - - ko:K09948 - - - - ko00000 - - - DUF1244 k141_15641_2 195105.CN97_18815 9.59e-15 74.3 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_10026_1 466088.CL42_06345 8.97e-56 197.0 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria,3NMKN@468|Moraxellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k141_17015_1 713586.KB900536_gene1367 3.92e-174 495.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales 135613|Chromatiales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_13528_1 396588.Tgr7_2958 6.49e-08 51.6 2EI8B@1|root,33BZN@2|Bacteria,1NGJZ@1224|Proteobacteria,1SGEM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2835) VV12640 - - - - - - - - - - - DUF2835 k141_13528_2 314345.SPV1_12225 6e-17 79.3 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif - - 3.6.4.12,3.6.4.13 ko:K03655,ko:K05592 ko03018,ko03440,map03018,map03440 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03400 - - - DbpA,RRM_1 k141_12868_1 246200.SPO1903 4.75e-27 100.0 COG4321@1|root,COG4321@2|Bacteria,1N7Z2@1224|Proteobacteria,2UF7W@28211|Alphaproteobacteria,4NCMN@97050|Ruegeria 28211|Alphaproteobacteria S Ribbon-helix-helix domain MA20_02235 - - - - - - - - - - - RHH_4 k141_12868_2 1188256.BASI01000002_gene3602 4.62e-46 155.0 COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,3FDV2@34008|Rhodovulum 28211|Alphaproteobacteria O Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k141_21928_1 1207063.P24_17912 2.9e-78 247.0 COG5285@1|root,COG5285@2|Bacteria,1RC96@1224|Proteobacteria,2U5V4@28211|Alphaproteobacteria,2JU95@204441|Rhodospirillales 204441|Rhodospirillales Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH k141_1726_1 1121937.AUHJ01000017_gene3058 3.49e-18 84.3 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,4661E@72275|Alteromonadaceae 1236|Gammaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_1726_2 1279019.ARQK01000043_gene2152 1.93e-46 153.0 COG2044@1|root,COG2044@2|Bacteria,1N1SD@1224|Proteobacteria,1SQMA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - ko:K07092 - - - - ko00000 - - - DrsE k141_306_1 697282.Mettu_0379 2.46e-26 108.0 COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria,1XFA4@135618|Methylococcales 135618|Methylococcales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP k141_7279_1 269798.CHU_2402 2.28e-30 114.0 COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,47K03@768503|Cytophagia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA,Succ_CoA_lig k141_12166_1 55601.VANGNB10_cI0973 1.59e-46 162.0 COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XSZM@135623|Vibrionales 135623|Vibrionales G COG1653 ABC-type sugar transport system, periplasmic component - - - ko:K17315 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - SBP_bac_1,SBP_bac_8 k141_12166_2 794903.OPIT5_19475 5.18e-06 47.4 COG0642@1|root,COG0642@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_6535_1 324602.Caur_1952 1.22e-15 84.7 COG0745@1|root,COG2198@1|root,COG2199@1|root,COG2204@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2204@2|Bacteria,COG2208@2|Bacteria,COG3706@2|Bacteria,2GANJ@200795|Chloroflexi,376V4@32061|Chloroflexia 32061|Chloroflexia T SMART protein phosphatase 2C domain protein - - - - - - - - - - - - GGDEF,Hpt,Response_reg,SpoIIE k141_8654_1 207954.MED92_03318 1.07e-11 68.6 COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T245@1236|Gammaproteobacteria,1XJ38@135619|Oceanospirillales 135619|Oceanospirillales T GGDEF domain - - - - - - - - - - - - GGDEF,NMT1,SBP_bac_3 k141_9326_1 5341.XP_007335711.1 2.21e-26 106.0 2AFWN@1|root,2RYYK@2759|Eukaryota,3A0HV@33154|Opisthokonta,3P3MV@4751|Fungi 4751|Fungi S LAGLIDADG endonuclease - - - - - - - - - - - - LAGLIDADG_1 k141_9326_2 1051613.XP_003009803.1 1.87e-27 109.0 COG0843@1|root,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3NYGG@4751|Fungi,3QSKE@4890|Ascomycota,21STW@147550|Sordariomycetes,1F541@1028384|Glomerellales 4751|Fungi Q Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B cox1 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.9.3.1 ko:K02256 ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016 M00154 - - ko00000,ko00001,ko00002,ko01000,ko03029 3.D.4.11,3.D.4.7,3.D.4.8 - - COX1 k141_3129_1 713586.KB900536_gene2820 3.32e-129 380.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 k141_19160_1 1049564.TevJSym_bi00190 6.8e-115 348.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_19160_2 398579.Spea_3550 0.000776 42.0 COG0697@1|root,COG0697@2|Bacteria,1N469@1224|Proteobacteria,1RQ1G@1236|Gammaproteobacteria,2QA92@267890|Shewanellaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_307_1 1278309.KB907103_gene1132 3.69e-120 352.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XHIG@135619|Oceanospirillales 135619|Oceanospirillales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_16298_1 637389.Acaty_m0165 1.3e-123 362.0 COG3677@1|root,COG3677@2|Bacteria,1R3ZS@1224|Proteobacteria,1SZQS@1236|Gammaproteobacteria,2NDTK@225057|Acidithiobacillales 1236|Gammaproteobacteria L Transposase zinc-ribbon domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_12869_2 204773.HEAR2065 9.53e-46 157.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,4730B@75682|Oxalobacteraceae 28216|Betaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_8029_1 102129.Lepto7375DRAFT_4747 1.03e-50 178.0 COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1G0VA@1117|Cyanobacteria,1H9ND@1150|Oscillatoriales 1117|Cyanobacteria T PFAM Adenylate and Guanylate cyclase catalytic domain cya1 - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - FHA,Guanylate_cyc k141_7280_1 1415779.JOMH01000001_gene363 1.92e-33 117.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1X7HR@135614|Xanthomonadales 135614|Xanthomonadales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_7280_2 305900.GV64_23065 1.52e-57 185.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XHKX@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB - - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_2383_1 1123487.KB892836_gene3236 1.83e-60 193.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria,2KW1S@206389|Rhodocyclales 206389|Rhodocyclales J Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_17017_1 1158182.KB905025_gene363 9.06e-57 196.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WWT2@135613|Chromatiales 135613|Chromatiales NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_3 k141_21929_1 1121939.L861_09600 2.17e-132 387.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1XHT9@135619|Oceanospirillales 135619|Oceanospirillales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_1727_1 1131553.JIBI01000039_gene1949 4.44e-80 244.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria,372WV@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_1727_2 870187.Thini_1080 3.41e-16 76.6 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_20576_1 643473.KB235930_gene3149 5.65e-72 223.0 COG0500@1|root,COG2226@2|Bacteria,1G3RV@1117|Cyanobacteria,1HMBB@1161|Nostocales 1117|Cyanobacteria Q methyltransferase - - - - - - - - - - - - - k141_20576_2 1286106.MPL1_02393 3.8e-36 128.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,460G6@72273|Thiotrichales 72273|Thiotrichales H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR k141_10028_1 1244869.H261_16493 9.37e-44 162.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2U4EG@28211|Alphaproteobacteria,2JRZA@204441|Rhodospirillales 204441|Rhodospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,Response_reg k141_308_1 443143.GM18_0651 2.23e-45 160.0 COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2WIM2@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM pseudaminic acid biosynthesis-associated protein PseG - - - - - - - - - - - - Acetyltransf_3,Glyco_tran_28_C k141_308_2 4952.CAG77697 1.46e-09 58.9 COG1028@1|root,KOG0725@2759|Eukaryota,38I37@33154|Opisthokonta,3NU20@4751|Fungi,3QR7D@4890|Ascomycota,3RU1S@4891|Saccharomycetes 4751|Fungi Q D-arabinitol 2-dehydrogenase ARDH GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044238,GO:0047038,GO:0055114,GO:0071704 1.1.1.250 ko:K17738 ko00040,ko01100,map00040,map01100 - R07134 RC00102 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_3790_2 1288826.MSNKSG1_16641 2.6e-200 556.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria 1224|Proteobacteria GM Epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind k141_3790_3 1288826.MSNKSG1_16636 6.92e-228 639.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,465CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2200 FOG EAL domain - - - - - - - - - - - - CBS,EAL,GGDEF k141_7281_1 1335757.SPICUR_03250 8.75e-125 364.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_8771_1 435908.IDSA_07490 2.99e-22 97.1 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,2QFDW@267893|Idiomarinaceae 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_3282_1 207954.MED92_16340 5.19e-22 97.1 COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,1S95Z@1236|Gammaproteobacteria,1XKQT@135619|Oceanospirillales 135619|Oceanospirillales M SprA-related family - - - - - - - - - - - - SprA-related k141_3282_2 439375.Oant_1878 1.76e-22 92.8 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2TT92@28211|Alphaproteobacteria,1J2EF@118882|Brucellaceae 28211|Alphaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids cobO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR k141_18567_2 1122599.AUGR01000004_gene2163 5.94e-33 121.0 COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,1S5P4@1236|Gammaproteobacteria,1XR0W@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_10203_1 1278309.KB907099_gene2574 2.24e-113 352.0 COG4564@1|root,COG5000@1|root,COG4564@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1T35N@1236|Gammaproteobacteria,1XRT7@135619|Oceanospirillales 135619|Oceanospirillales T Cache_2 - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2 k141_4670_1 203122.Sde_0519 8.73e-29 115.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_9442_1 335543.Sfum_0366 4.36e-80 250.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MQA7@213462|Syntrophobacterales 28221|Deltaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k141_7436_1 717774.Marme_3311 9.38e-41 142.0 COG4176@1|root,COG4176@2|Bacteria,1QTTE@1224|Proteobacteria,1S03C@1236|Gammaproteobacteria,1XR6V@135619|Oceanospirillales 135619|Oceanospirillales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_7436_2 1122599.AUGR01000010_gene1059 7.58e-178 504.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RY4K@1236|Gammaproteobacteria,1XHHR@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter - - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran k141_15828_1 1266998.ATUJ01000016_gene988 2.51e-40 151.0 COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,2TTAJ@28211|Alphaproteobacteria,2PW3U@265|Paracoccus 28211|Alphaproteobacteria M Capsule polysaccharide biosynthesis protein kpsC - - ko:K07266 - - - - ko00000 - - - Capsule_synth k141_19940_1 1116472.MGMO_139c00110 8.59e-73 229.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1XDSY@135618|Methylococcales 135618|Methylococcales P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_17171_1 1118153.MOY_12479 5.23e-16 77.4 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XNJI@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_9,Response_reg k141_17171_3 1283284.AZUK01000002_gene2776 2.1e-12 67.0 COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1RRSJ@1236|Gammaproteobacteria,1Y5K1@135624|Aeromonadales 135624|Aeromonadales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Response_reg,dCache_1 k141_1188_1 1086011.HJ01_00870 6.94e-104 317.0 COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia,2P028@237|Flavobacterium 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family sglT - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_5357_1 1207063.P24_04260 8.24e-09 57.4 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2JPRF@204441|Rhodospirillales 204441|Rhodospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short,adh_short_C2 k141_5357_2 633131.TR2A62_2222 1.38e-40 144.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_479_1 1100721.ALKO01000027_gene380 8.72e-12 64.7 COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,2VMDW@28216|Betaproteobacteria,4ACGI@80864|Comamonadaceae 28216|Betaproteobacteria G PFAM extracellular solute-binding protein family 1 - - - ko:K02027,ko:K10227 ko02010,map02010 M00200,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.5 - - SBP_bac_1,SBP_bac_8 k141_479_2 1123360.thalar_03095 6.62e-38 134.0 COG1175@1|root,COG1175@2|Bacteria,1MVF1@1224|Proteobacteria,2TST1@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type sugar transport systems permease components smoF - - ko:K10228 ko02010,map02010 M00200 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.5 - - BPD_transp_1 k141_6678_1 472759.Nhal_0548 3.9e-64 211.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_13053_1 1031711.RSPO_c00550 1.3e-10 61.6 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,1K1VS@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_13053_2 1123401.JHYQ01000028_gene3184 8.51e-185 523.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,460BB@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_9443_1 1278309.KB907100_gene1778 1.59e-117 377.0 COG0604@1|root,COG3321@1|root,COG0604@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria,1XHY4@135619|Oceanospirillales 135619|Oceanospirillales Q Polyketide synthase modules and related - - - - - - - - - - - - ADH_N,ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt k141_2521_2 1121935.AQXX01000087_gene4641 7.02e-99 300.0 28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,1RRFF@1236|Gammaproteobacteria,1XNPV@135619|Oceanospirillales 135619|Oceanospirillales S General glycosylation pathway protein - - - - - - - - - - - - - k141_11599_1 768066.HELO_1880 1.51e-23 110.0 COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1XI7D@135619|Oceanospirillales 135619|Oceanospirillales H COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_6,TPR_8 k141_10204_1 472759.Nhal_3447 2.68e-135 399.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales 135613|Chromatiales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_12345_1 743299.Acife_1818 8.96e-100 301.0 COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,2NC25@225057|Acidithiobacillales 225057|Acidithiobacillales S 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 k141_12345_2 765914.ThisiDRAFT_0872 1.09e-126 368.0 COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,1WYHT@135613|Chromatiales 135613|Chromatiales CH Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - - - - - - - - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_12345_3 765914.ThisiDRAFT_0873 2.87e-20 87.4 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Coenzyme F420-reducing hydrogenase, gamma subunit hoxY - - - - - - - - - - - Oxidored_q6 k141_20684_1 1288826.MSNKSG1_14382 2.55e-184 514.0 COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,464D3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain luxR - - - - - - - - - - - GerE,Response_reg k141_20684_2 1288826.MSNKSG1_14377 0.0 1553.0 COG0642@1|root,COG0745@1|root,COG1457@1|root,COG0745@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,464VX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_7437_1 1163409.UUA_05787 1.86e-24 105.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1X73J@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents auxiliary component - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_3916_1 1090318.ATTI01000001_gene1700 4.61e-07 54.3 COG1261@1|root,COG1261@2|Bacteria,1PM4C@1224|Proteobacteria,2TRUS@28211|Alphaproteobacteria,2K6AN@204457|Sphingomonadales 204457|Sphingomonadales NO Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly - - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_19941_1 1123514.KB905900_gene2067 4.34e-77 236.0 COG2850@1|root,COG2850@2|Bacteria,1RDTN@1224|Proteobacteria,1SDPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_19941_2 1005048.CFU_0019 2.52e-55 178.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,2VTM1@28216|Betaproteobacteria,477P4@75682|Oxalobacteraceae 28216|Betaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_21403_1 768671.ThimaDRAFT_3437 7.75e-60 189.0 COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,1S56W@1236|Gammaproteobacteria,1WYDD@135613|Chromatiales 135613|Chromatiales F pfam nudix - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_21403_2 561231.Pecwa_4071 1.49e-29 111.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1MSHZ@122277|Pectobacterium 1236|Gammaproteobacteria J Belongs to the HSP15 family hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_21403_3 765911.Thivi_1828 1.24e-74 245.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales 135613|Chromatiales S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_480_1 1278309.KB907099_gene2757 1.06e-16 76.3 COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,1SA2T@1236|Gammaproteobacteria,1XKVA@135619|Oceanospirillales 135619|Oceanospirillales O HupE / UreJ protein - - - ko:K03192 - - - - ko00000 - - - HupE_UreJ k141_480_2 1126627.BAWE01000002_gene462 9.37e-05 48.9 COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,3JTG9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_1189_1 1278309.KB907104_gene823 1.86e-121 367.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XIYM@135619|Oceanospirillales 135619|Oceanospirillales M Rhs element Vgr protein - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_1189_2 1278309.KB907100_gene1901 2.01e-93 278.0 COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1XIEJ@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_10937_1 1056820.KB900631_gene2356 1.56e-41 142.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,2PNPB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S RimP C-terminal SH3 domain rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_10937_3 631362.Thi970DRAFT_01660 3.66e-37 132.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1WXZY@135613|Chromatiales 135613|Chromatiales S Sulfur oxidation protein SoxY - - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_10937_4 93220.LV28_13550 7.65e-29 107.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,1K8XJ@119060|Burkholderiaceae 28216|Betaproteobacteria S oxidation protein soxZ - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ k141_10937_5 317025.Tcr_2158 6.32e-26 103.0 COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,1S6P0@1236|Gammaproteobacteria,462TC@72273|Thiotrichales 72273|Thiotrichales S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_10937_6 1000565.METUNv1_01604 8.69e-05 43.9 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KVV3@206389|Rhodocyclales 206389|Rhodocyclales T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_5992_1 207954.MED92_07841 5.16e-207 578.0 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,1XHKE@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyl transferase - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_5992_2 207954.MED92_07836 1.95e-204 582.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1XHYU@135619|Oceanospirillales 135619|Oceanospirillales G Alpha amylase, catalytic domain - - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_4671_1 1479237.JMLY01000001_gene1623 1.82e-45 150.0 COG2105@1|root,COG2105@2|Bacteria,1RH3X@1224|Proteobacteria,1S68T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AIG2 family ytfP GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - GGACT k141_4671_2 1318628.MARLIPOL_13009 1.24e-133 386.0 COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,1RNIC@1236|Gammaproteobacteria,467JU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator argP GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032297,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090329,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000104,GO:2000112,GO:2000113,GO:2001141 - ko:K05596 - - - - ko00000,ko03000,ko03036 - - - HTH_1,LysR_substrate k141_1855_1 1122963.AUHB01000003_gene3837 8.3e-105 314.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily aglK - - ko:K10111,ko:K10235 ko02010,map02010 M00194,M00200,M00201,M00204,M00207,M00491 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.8 - - ABC_tran,TOBE_2 k141_1855_2 570967.JMLV01000008_gene1380 2.92e-09 63.9 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria,2JPQP@204441|Rhodospirillales 204441|Rhodospirillales C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_2522_1 371731.Rsw2DRAFT_1201 8.85e-123 358.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,1FARK@1060|Rhodobacter 28211|Alphaproteobacteria H Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_12363_2 377629.TERTU_4452 3.02e-112 331.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RYX7@1236|Gammaproteobacteria,2PQJR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L hmm pf00665 - - - - - - - - - - - - HTH_21,rve k141_12363_5 1120954.ATXE01000001_gene1952 1.28e-21 98.6 2CBE1@1|root,32RT5@2|Bacteria,2I05I@201174|Actinobacteria,4DVVG@85009|Propionibacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - k141_12363_6 1538295.JY96_18405 8.64e-32 117.0 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,1KN9K@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 k141_10221_1 1288826.MSNKSG1_10583 4.67e-144 407.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,463ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW k141_10221_2 1288826.MSNKSG1_10588 1.13e-71 220.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,467BB@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_3299_3 1089550.ATTH01000001_gene730 8.78e-33 120.0 COG1833@1|root,COG1833@2|Bacteria,4PF8V@976|Bacteroidetes,1FKAW@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Domain of unknown function DUF123 - - - - - - - - - - - - DUF123 k141_3299_4 233412.HD_0196 8.96e-51 167.0 COG1755@1|root,COG1755@2|Bacteria,1MY6Q@1224|Proteobacteria,1SPG0@1236|Gammaproteobacteria,1Y8JK@135625|Pasteurellales 135625|Pasteurellales S protein conserved in bacteria - - - - - - - - - - - - ICMT k141_3299_5 1294143.H681_15605 2.31e-13 66.6 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_15844_1 670292.JH26_01940 8.36e-11 62.0 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2UCYK@28211|Alphaproteobacteria,1JY02@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp k141_15844_2 1234364.AMSF01000046_gene1991 2.51e-31 113.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria,1X7X2@135614|Xanthomonadales 135614|Xanthomonadales P Ion channel - - - - - - - - - - - - Ion_trans_2 k141_6003_1 1042375.AFPL01000056_gene2383 1.2e-88 265.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_6687_1 519989.ECTPHS_06972 9.93e-107 326.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales 135613|Chromatiales O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_15085_1 349521.HCH_00224 1.67e-52 187.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XHMF@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_2543_1 1384054.N790_13260 9.49e-06 46.2 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales 135614|Xanthomonadales K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_22072_4 671143.DAMO_0362 1.8e-121 356.0 COG2837@1|root,COG2837@2|Bacteria 2|Bacteria P iron assimilation dyp - - ko:K07223 - - - - ko00000 - - - Dyp_perox k141_22072_5 998674.ATTE01000001_gene824 4.07e-139 407.0 COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,1RP1Y@1236|Gammaproteobacteria,4622I@72273|Thiotrichales 72273|Thiotrichales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_18583_1 551275.KB899544_gene1711 1.43e-24 103.0 COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,2U6AC@28211|Alphaproteobacteria,43X52@69657|Hyphomonadaceae 28211|Alphaproteobacteria S membrane - - - - - - - - - - - - DUF389 k141_18583_3 1168067.JAGP01000001_gene921 1.09e-133 384.0 COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria 1236|Gammaproteobacteria T membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF347 k141_18583_4 396588.Tgr7_0347 1.78e-19 85.9 2BZD1@1|root,32XYD@2|Bacteria,1N516@1224|Proteobacteria,1S961@1236|Gammaproteobacteria,1X1EP@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_4801_4 1278309.KB907107_gene1667 2.9e-80 240.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1XJYW@135619|Oceanospirillales 135619|Oceanospirillales S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY k141_4801_5 1278309.KB907107_gene1668 0.0 1081.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XHNC@135619|Oceanospirillales 135619|Oceanospirillales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_4801_6 1278309.KB907107_gene1669 7.12e-303 837.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XHWC@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_11082_1 1415778.JQMM01000001_gene2178 4.59e-92 275.0 COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_11082_2 1415778.JQMM01000001_gene2177 2.5e-40 135.0 2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_11082_3 1288826.MSNKSG1_00551 1.89e-48 159.0 COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C epsilon subunit - - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_11082_4 1415778.JQMM01000001_gene2175 6.27e-13 68.2 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_7562_1 713586.KB900536_gene118 3.9e-94 291.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales 135613|Chromatiales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_8321_1 1278309.KB907102_gene8 6.59e-126 375.0 COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,1XIRH@135619|Oceanospirillales 135619|Oceanospirillales M O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_4004_1 266809.PM03_10560 1.86e-118 353.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_15163_1 1288826.MSNKSG1_09838 3.78e-55 178.0 COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,464AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S DUF1338 - - - - - - - - - - - - DUF1338 k141_15163_2 1288826.MSNKSG1_09843 2.58e-144 408.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_15163_3 1288826.MSNKSG1_09848 5.44e-152 427.0 2A4V5@1|root,30TGR@2|Bacteria,1NG0N@1224|Proteobacteria,1S4KH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13205_1 545264.KB898746_gene756 2.94e-88 283.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_22213_2 754476.Q7A_800 2.01e-101 307.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,45ZVY@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k141_9604_1 765914.ThisiDRAFT_1543 2.55e-21 90.9 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_9604_2 95619.PM1_0218220 1.6e-147 424.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_12520_1 292415.Tbd_2651 4.08e-76 238.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1KRUR@119069|Hydrogenophilales 119069|Hydrogenophilales K LysR substrate binding domain - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_1350_1 443144.GM21_2424 4.95e-49 165.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2WITT@28221|Deltaproteobacteria,43U4S@69541|Desulfuromonadales 28221|Deltaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_19439_1 1278309.KB907101_gene485 2.65e-165 473.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIC9@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes - - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_10375_1 1116472.MGMO_20c00160 1.34e-21 92.0 COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria 1224|Proteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_10375_2 574376.BAMA_13430 3.47e-09 58.9 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF k141_2683_1 2340.JV46_06490 1.53e-171 487.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1J4F3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_8335_1 1151127.KB906331_gene3447 9.4e-78 241.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1YND9@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_8335_2 713587.THITH_17445 8e-44 146.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1WYB4@135613|Chromatiales 135613|Chromatiales J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_8907_1 998674.ATTE01000001_gene2261 9.19e-35 138.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,4604N@72273|Thiotrichales 72273|Thiotrichales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_20777_1 686340.Metal_2130 3.16e-101 305.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1T9DW@1236|Gammaproteobacteria,1XG6V@135618|Methylococcales 135618|Methylococcales C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_22214_1 314345.SPV1_06144 3.6e-57 191.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria 1224|Proteobacteria E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_22214_2 314345.SPV1_06149 7.85e-49 162.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria 1224|Proteobacteria F Creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_18104_1 1121374.KB891576_gene314 1.71e-17 79.3 2E8EX@1|root,332TA@2|Bacteria,1N97B@1224|Proteobacteria,1SDNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11104_1 351348.Maqu_0657 2.71e-93 284.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,465SY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k141_2684_1 395493.BegalDRAFT_3384 2.51e-55 187.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,45ZQ0@72273|Thiotrichales 72273|Thiotrichales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_17316_1 765912.Thimo_3548 1.15e-77 245.0 2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria,1WZX3@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_16618_1 1122604.JONR01000010_gene3941 3.24e-129 377.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X5US@135614|Xanthomonadales 135614|Xanthomonadales F Phosphohydrolase-associated domain - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_16618_2 396588.Tgr7_3030 5.44e-110 327.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_13206_1 1318628.MARLIPOL_04040 8.86e-113 331.0 COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,4662D@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds mhpE - 2.3.3.13,4.1.3.39,4.1.3.43 ko:K01649,ko:K01666,ko:K18365 ko00290,ko00360,ko00362,ko00620,ko00621,ko00622,ko01100,ko01110,ko01120,ko01210,ko01220,ko01230,map00290,map00360,map00362,map00620,map00621,map00622,map01100,map01110,map01120,map01210,map01220,map01230 M00432,M00545,M00569 R00750,R01213,R05298 RC00004,RC00307,RC00371,RC00470,RC00572,RC02754 br01601,br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k141_1987_1 1049564.TevJSym_ag01030 1.45e-59 198.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1J5DY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_1987_2 1026882.MAMP_00793 8.17e-19 87.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,463I0@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 k141_10377_1 1121935.AQXX01000121_gene5560 3.94e-72 226.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1XIBG@135619|Oceanospirillales 135619|Oceanospirillales M Polysaccharide biosynthesis protein - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_18743_1 1278309.KB907099_gene2952 1.07e-90 281.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1XH5J@135619|Oceanospirillales 135619|Oceanospirillales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_18743_2 1278309.KB907099_gene2953 2.91e-114 330.0 COG3467@1|root,COG3467@2|Bacteria,1MWQE@1224|Proteobacteria,1S4WW@1236|Gammaproteobacteria,1XJN0@135619|Oceanospirillales 135619|Oceanospirillales S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 k141_12521_1 1163617.SCD_n02361 2.62e-133 400.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3 k141_19440_1 744979.R2A130_3259 9.54e-125 375.0 COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2TRRK@28211|Alphaproteobacteria 28211|Alphaproteobacteria I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons pct - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_11105_1 1523503.JPMY01000004_gene1640 2.1e-74 233.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S3EV@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_18105_1 566466.NOR53_539 2.48e-22 95.1 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1J9I8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_18105_2 713587.THITH_15860 5.7e-74 226.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1WVVN@135613|Chromatiales 135613|Chromatiales EH TIGRFAM glutamine amidotransferase of anthranilate synthase - - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_22215_3 1449050.JNLE01000005_gene4444 5.51e-07 53.5 COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36DJA@31979|Clostridiaceae 186801|Clostridia P Belongs to the sulfur carrier protein TusA family cdr - - - - - - - - - - - DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA k141_8336_1 870187.Thini_3864 1.97e-21 87.4 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_8336_2 1397528.Q671_11755 6.14e-75 234.0 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,1S3HN@1236|Gammaproteobacteria,1XJIE@135619|Oceanospirillales 135619|Oceanospirillales S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_10378_2 1120985.AUMI01000011_gene283 2.93e-25 96.3 COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes 1239|Firmicutes P multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_17317_1 765911.Thivi_1763 1.83e-83 259.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_17317_2 1001585.MDS_4407 2.74e-08 55.5 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1YDS8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_9606_1 1095769.CAHF01000022_gene432 9.04e-15 82.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_1988_1 398580.Dshi_1228 1.78e-46 154.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein possibly involved in utilization of glycolate and propanediol - - - - - - - - - - - - Haem_degrading k141_1988_2 1121479.AUBS01000008_gene957 3.51e-08 53.9 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_18106_1 1088721.NSU_3635 6.98e-42 141.0 COG3384@1|root,COG3384@2|Bacteria,1RIBC@1224|Proteobacteria,2UET5@28211|Alphaproteobacteria,2KA6Q@204457|Sphingomonadales 204457|Sphingomonadales S Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA k141_18106_2 288000.BBta_2734 6.02e-11 61.2 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,3JVRK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase mhpB - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB k141_16620_1 1123247.AUIJ01000003_gene1975 4.49e-23 94.7 COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2U933@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q dienelactone hydrolase - - - - - - - - - - - - DLH k141_16620_2 1461693.ATO10_01910 1.34e-06 48.9 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_20778_1 1049564.TevJSym_au00160 8.68e-217 614.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_8911_1 983545.Glaag_3366 4.99e-156 447.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,465FN@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_13207_1 1288826.MSNKSG1_07103 2.31e-170 475.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,465CK@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the SAICAR synthetase family purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 SAICAR_synt k141_13207_2 1288826.MSNKSG1_07098 1.14e-54 178.0 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,467AR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_10379_1 472759.Nhal_1290 1.26e-134 421.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales 135613|Chromatiales L TIGRFAM ATP-dependent helicase HrpA - - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_9607_1 349124.Hhal_1056 1.69e-05 45.8 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_9607_2 1283300.ATXB01000001_gene2086 6.09e-10 64.3 COG0741@1|root,COG3266@1|root,COG0741@2|Bacteria,COG3266@2|Bacteria,1MWRW@1224|Proteobacteria,1S084@1236|Gammaproteobacteria,1XEU5@135618|Methylococcales 135618|Methylococcales M lytic transglycosylase activity - - - - - - - - - - - - - k141_20779_1 1168289.AJKI01000014_gene2052 5.36e-34 123.0 COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,2FTXH@200643|Bacteroidia,3XKUU@558415|Marinilabiliaceae 976|Bacteroidetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_4818_1 399742.Ent638_1051 1.35e-11 65.1 29XAK@1|root,30J05@2|Bacteria,1PFT8@1224|Proteobacteria,1TAKQ@1236|Gammaproteobacteria,3X45C@547|Enterobacter 399742.Ent638_1051|- - - - - - - - - - - - - - - - k141_13885_3 468059.AUHA01000003_gene1673 7.19e-55 177.0 2DJN0@1|root,306NJ@2|Bacteria,4P418@976|Bacteroidetes 976|Bacteroidetes S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863 k141_13885_4 1134474.O59_004011 1.12e-112 328.0 28IG0@1|root,2Z8HI@2|Bacteria,1R5X7@1224|Proteobacteria,1S70E@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13885_5 717774.Marme_2229 6.62e-22 95.1 2B1Z8@1|root,31UFT@2|Bacteria,1RHY7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - TIR_2 k141_8912_1 1123401.JHYQ01000003_gene2059 2.38e-61 206.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3 k141_12524_1 314345.SPV1_00967 1.56e-93 300.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 - - - ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,PTS_EIIA_2 k141_16621_1 1453501.JELR01000002_gene666 9.43e-39 141.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k141_16621_2 1097668.BYI23_A020900 3.1e-30 118.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,1K2JJ@119060|Burkholderiaceae 28216|Betaproteobacteria I Acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_13208_2 472759.Nhal_1512 8.49e-54 179.0 COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1WWUS@135613|Chromatiales 135613|Chromatiales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metAS - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS k141_10380_1 686340.Metal_2066 8.09e-110 333.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XER8@135618|Methylococcales 135618|Methylococcales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_3429_1 1278309.KB907103_gene1125 1.09e-150 434.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XIQG@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_3429_2 1278309.KB907103_gene1126 2.05e-144 408.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1XHAX@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_3429_3 1278309.KB907103_gene1127 1.76e-238 658.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XH6T@135619|Oceanospirillales 135619|Oceanospirillales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_3429_4 1278309.KB907103_gene1128 1.8e-251 692.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XHYW@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_3429_5 1278309.KB907103_gene1129 2.64e-187 566.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XIW5@135619|Oceanospirillales 135619|Oceanospirillales NU Tfp pilus assembly protein - - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_16622_1 367336.OM2255_03845 5.37e-127 362.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolase of the alpha beta superfamily QU41_16170 - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 k141_20780_1 396588.Tgr7_2065 6.19e-56 185.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_20780_2 1121935.AQXX01000135_gene3659 6.86e-21 91.7 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XHAC@135619|Oceanospirillales 135619|Oceanospirillales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_8404_3 28229.ND2E_3902 5.69e-43 157.0 COG0277@1|root,COG0277@2|Bacteria 2|Bacteria C FAD linked oxidase domain protein - - 1.1.3.8 ko:K00103 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 k141_4205_1 1288826.MSNKSG1_09283 3.07e-164 465.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,465RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_4205_3 1288826.MSNKSG1_09273 2.34e-300 820.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,464MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_4205_4 1288826.MSNKSG1_09268 4.2e-200 564.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,464H8@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease hflK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_4205_5 1288826.MSNKSG1_09263 2.19e-191 533.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,465JS@72275|Alteromonadaceae 1236|Gammaproteobacteria O HflC and HflK could regulate a protease hflC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_4205_6 1288826.MSNKSG1_09258 7.22e-282 770.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4649K@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_4205_7 1288826.MSNKSG1_09253 2.05e-314 856.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,464CH@72275|Alteromonadaceae 1236|Gammaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Adenylsucc_synt k141_4205_8 1288826.MSNKSG1_09248 2.43e-239 657.0 COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,464Q9@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_4205_9 1288826.MSNKSG1_09243 3.82e-176 491.0 COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria,465MI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_4205_10 1288826.MSNKSG1_09238 7.14e-78 232.0 2EMJH@1|root,33F81@2|Bacteria,1NHQJ@1224|Proteobacteria,1SJCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4205_11 1288826.MSNKSG1_09233 8.92e-248 679.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,464EM@72275|Alteromonadaceae 1236|Gammaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - APH k141_4205_12 1288826.MSNKSG1_09228 1.36e-246 679.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria,46646@72275|Alteromonadaceae 1236|Gammaproteobacteria S FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_4205_13 1288826.MSNKSG1_09223 4.63e-100 292.0 COG1040@1|root,COG1040@2|Bacteria 2|Bacteria K competence protein comF GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_4205_14 1288826.MSNKSG1_09218 1.35e-236 651.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_11211_1 571166.KI421509_gene1073 3.89e-50 177.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG1982 Arginine lysine ornithine decarboxylases - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_2121_2 314271.RB2654_15751 7.07e-15 75.1 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_7024_1 379731.PST_1123 1.31e-12 76.3 COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNG@1236|Gammaproteobacteria,1Z02U@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg k141_11887_1 1298593.TOL_0842 8.65e-56 194.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XI39@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein - - - ko:K07121 - - - - ko00000 - - - LppC k141_1431_1 1002340.AFCF01000062_gene650 7.54e-84 267.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TRBN@28211|Alphaproteobacteria,34DZX@302485|Phaeobacter 28211|Alphaproteobacteria EQ Hydantoinase/oxoprolinase N-terminal region - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A k141_18162_1 391613.RTM1035_11070 9.45e-54 177.0 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,46PHW@74030|Roseovarius 28211|Alphaproteobacteria E COG3741 N-formylglutamate amidohydrolase MA20_06380 - 3.5.1.68 ko:K01458 ko00340,ko00630,map00340,map00630 - R00525 RC00165,RC00323 ko00000,ko00001,ko01000 - - - FGase k141_20969_1 313598.MED152_06995 1.28e-31 122.0 29DC6@1|root,300A0@2|Bacteria,4NNIQ@976|Bacteroidetes,1I217@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_20264_1 1288826.MSNKSG1_18360 1.81e-79 245.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,4647W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0516 DHBP_synthase,GTP_cyclohydro2 k141_20264_2 1288826.MSNKSG1_18365 3.27e-104 301.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,466GG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0380 DMRL_synthase k141_20264_3 1288826.MSNKSG1_18370 1.33e-103 300.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,467Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_20264_4 1288826.MSNKSG1_18375 1.84e-196 548.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,466CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0382 AIRS,AIRS_C k141_20264_5 1288826.MSNKSG1_18380 1.64e-128 364.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,467H1@72275|Alteromonadaceae 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA k141_20264_6 1288826.MSNKSG1_18385 4.33e-46 147.0 2EJYG@1|root,33DP3@2|Bacteria,1NIGJ@1224|Proteobacteria,1SH50@1236|Gammaproteobacteria,46C7C@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20264_7 1288826.MSNKSG1_18390 1.57e-128 368.0 COG3110@1|root,COG3110@2|Bacteria,1NMI8@1224|Proteobacteria 1224|Proteobacteria S Belongs to the UPF0319 family - - - ko:K09909 - - - - ko00000 - - - DUF2057 k141_20264_8 1288826.MSNKSG1_18395 0.0 985.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RZG3@1236|Gammaproteobacteria,466R7@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf k141_20264_9 1288826.MSNKSG1_18400 1.75e-215 597.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,466EN@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator yeeY - - - - - - - - - - - HTH_1,LysR_substrate k141_20264_10 1288826.MSNKSG1_18405 1.17e-245 673.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,4651K@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase yqjG - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_20264_11 1288826.MSNKSG1_18410 2.45e-219 606.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,4645T@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt k141_20264_12 1288826.MSNKSG1_18415 4.28e-67 203.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,467GE@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_20264_13 1288826.MSNKSG1_18420 4.74e-54 169.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,467SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_20264_14 1288826.MSNKSG1_18425 8.71e-245 676.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_7718_1 1288826.MSNKSG1_14487 1.08e-122 361.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,465MW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Hexapep,Hexapep_2,NTP_transf_3 k141_7718_2 1288826.MSNKSG1_14492 1.76e-88 260.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,4679J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iJN746.PP_5412 ATP-synt_DE,ATP-synt_DE_N k141_7718_3 1288826.MSNKSG1_14497 0.0 899.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,465I5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 ATP-synt_ab,ATP-synt_ab_N k141_7718_4 1288826.MSNKSG1_14502 1.62e-196 546.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,4655C@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSSON_1240.SSON_3886,iYL1228.KPN_04138 ATP-synt k141_7718_5 1288826.MSNKSG1_14507 0.0 976.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,464BU@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_7718_6 1288826.MSNKSG1_14512 1.81e-113 327.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,467HG@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 OSCP k141_7718_7 1288826.MSNKSG1_14517 9.48e-71 217.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,4670M@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 ATP-synt_B k141_7718_8 1288826.MSNKSG1_14522 1.62e-42 139.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,468H6@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_7718_9 1288826.MSNKSG1_14527 3.23e-217 600.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,464QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 ATP-synt_A k141_7718_10 1288826.MSNKSG1_14532 2.6e-90 265.0 COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,468Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3312 F0F1-type ATP synthase, subunit I atpI GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_7718_11 1288826.MSNKSG1_14537 1.62e-197 548.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,4649M@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_7718_12 1288826.MSNKSG1_14542 1.68e-181 506.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,464DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_7718_13 1288826.MSNKSG1_14547 8.75e-139 393.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,466SB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_7718_14 1288826.MSNKSG1_14552 0.0 1233.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,465DI@72275|Alteromonadaceae 1236|Gammaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_9104_1 1123228.AUIH01000004_gene1113 3.45e-141 414.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XHAH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_4912_1 215803.DB30_6401 1.07e-36 131.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,42SPX@68525|delta/epsilon subdivisions,2WPM4@28221|Deltaproteobacteria,2YUQ4@29|Myxococcales 28221|Deltaproteobacteria O glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_4912_2 396588.Tgr7_0347 7.84e-21 90.5 2BZD1@1|root,32XYD@2|Bacteria,1N516@1224|Proteobacteria,1S961@1236|Gammaproteobacteria,1X1EP@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_15411_1 631362.Thi970DRAFT_04697 2.83e-179 536.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_4218_1 1120948.KB903246_gene3294 1.02e-08 59.3 COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4DYEZ@85010|Pseudonocardiales 201174|Actinobacteria S PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB k141_4218_2 1122212.AULO01000013_gene2020 1.58e-34 122.0 COG1018@1|root,COG1018@2|Bacteria,1NA1K@1224|Proteobacteria,1SCMJ@1236|Gammaproteobacteria,1XM12@135619|Oceanospirillales 135619|Oceanospirillales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2 k141_4218_3 1278309.KB907108_gene1597 3.52e-217 599.0 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,1RY4A@1236|Gammaproteobacteria,1XHX9@135619|Oceanospirillales 135619|Oceanospirillales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_20281_1 713586.KB900536_gene3032 2.47e-70 224.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1WWEM@135613|Chromatiales 135613|Chromatiales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_13310_1 1288826.MSNKSG1_16596 0.0 1077.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,465EX@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_750_1 1336233.JAEH01000004_gene1556 2.57e-86 263.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,2Q94A@267890|Shewanellaceae 1236|Gammaproteobacteria H Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_2698 Meth_synt_2 k141_750_2 207954.MED92_05643 1.71e-168 474.0 28H5S@1|root,2Z7IA@2|Bacteria,1MX3X@1224|Proteobacteria,1RPVF@1236|Gammaproteobacteria,1XHVW@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1852) - - - - - - - - - - - - DUF1852 k141_15413_1 1123247.AUIJ01000004_gene1004 7.99e-107 318.0 COG1071@1|root,COG1071@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor - - - - - - - - - - - - E1_dh k141_11909_2 1348114.OM33_21485 7.26e-24 92.4 2EH60@1|root,33AXW@2|Bacteria,1N75V@1224|Proteobacteria,1TB5V@1236|Gammaproteobacteria,2Q3AH@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2798) - - - - - - - - - - - - DUF2798 k141_11909_3 1232410.KI421421_gene3874 2.91e-30 112.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42QT6@68525|delta/epsilon subdivisions,2WNC5@28221|Deltaproteobacteria,43W1X@69541|Desulfuromonadales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_5652_2 926560.KE387023_gene2755 8.47e-70 222.0 COG2897@1|root,COG2897@2|Bacteria,1WKXR@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P Sulfurtransferase - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_4220_1 1208321.D104_12595 6.75e-84 256.0 COG2186@1|root,COG2186@2|Bacteria,1R68P@1224|Proteobacteria,1S559@1236|Gammaproteobacteria,1XPTV@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_21006_1 1288826.MSNKSG1_12502 6.17e-273 751.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464I1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0417 Anth_synt_I_N,Chorismate_bind k141_21006_2 1288826.MSNKSG1_12507 1.32e-136 386.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,4641F@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0512 Anthranilate para-aminobenzoate synthases component II pabA GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135 GATase k141_21006_3 1288826.MSNKSG1_12512 2.2e-54 179.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_11245_1 994479.GL877878_gene1278 1.42e-09 60.5 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DXJG@85010|Pseudonocardiales 201174|Actinobacteria S associated with various cellular activities moxR1 - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_11245_2 522306.CAP2UW1_1369 1.71e-41 152.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria 28216|Betaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_16082_2 1195073.I6WLQ1_9CAUD 6.44e-29 115.0 4QG5T@10239|Viruses,4QYVN@35237|dsDNA viruses no RNA stage,4QTYJ@28883|Caudovirales,4QNPX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k141_8414_1 1288826.MSNKSG1_07218 6.59e-149 428.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,464Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_8414_2 1288826.MSNKSG1_07223 3.2e-240 660.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,464WV@72275|Alteromonadaceae 1236|Gammaproteobacteria M UDP-glucose 4-epimerase galE - 5.1.3.2,5.1.3.5 ko:K01784,ko:K12448 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01473,R02984 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_8414_3 1288826.MSNKSG1_07228 2.38e-103 300.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,467E7@72275|Alteromonadaceae 1236|Gammaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 k141_8414_4 1288826.MSNKSG1_07233 0.0 1041.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,4657S@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 GATase,GMP_synt_C,NAD_synthase k141_8414_5 1288826.MSNKSG1_07238 0.0 922.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,464HQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO k141_8414_6 1288826.MSNKSG1_07243 2.34e-263 730.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,464M5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_8414_7 1288826.MSNKSG1_07248 0.0 1262.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,463YE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases prpE - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_8414_8 1288826.MSNKSG1_07253 4.1e-45 145.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,4689P@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_8414_9 1288826.MSNKSG1_07258 4.05e-237 662.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4656N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_21007_1 1168067.JAGP01000001_gene1837 1.72e-110 338.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales 72273|Thiotrichales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_13998_1 1278309.KB907110_gene3165 3.13e-165 468.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XRE0@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_13998_2 1278309.KB907110_gene3164 1.57e-111 323.0 COG0778@1|root,COG0778@2|Bacteria,1RBZQ@1224|Proteobacteria,1S328@1236|Gammaproteobacteria,1XS4Y@135619|Oceanospirillales 135619|Oceanospirillales C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_13998_3 1278309.KB907110_gene3163 1.52e-22 91.7 2E37U@1|root,32Y7H@2|Bacteria,1N8JQ@1224|Proteobacteria,1SCAH@1236|Gammaproteobacteria,1XKZH@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2956) - - - - - - - - - - - - DUF2956 k141_11910_1 748658.KB907312_gene1662 3.92e-77 249.0 COG2310@1|root,COG2310@2|Bacteria,1N7Q6@1224|Proteobacteria,1RYFB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T stress, protein - - - - - - - - - - - - - k141_20284_1 1469613.JT55_14740 3.77e-87 271.0 COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,3FDF1@34008|Rhodovulum 28211|Alphaproteobacteria U AAA domain minD - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31 k141_13392_1 1288826.MSNKSG1_11428 5.28e-61 214.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_840_1 1026882.MAMP_02166 2.23e-42 148.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RPUE@1236|Gammaproteobacteria,461MV@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could encode or regulate a protease - - - - - - - - - - - - Band_7 k141_840_2 999141.GME_11202 3.37e-08 53.1 COG0645@1|root,COG0645@2|Bacteria,1RDGW@1224|Proteobacteria,1S7GV@1236|Gammaproteobacteria,1XPBX@135619|Oceanospirillales 135619|Oceanospirillales D AAA domain - - - - - - - - - - - - AAA_33 k141_1521_1 313612.L8106_24810 8.8e-64 219.0 COG4251@1|root,COG5001@1|root,COG4251@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales 1117|Cyanobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,FHA,GAF,GAF_2,GGDEF,PAS_3,PAS_9,PHY k141_4322_1 983545.Glaag_3207 2.53e-78 245.0 COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,464GV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Lipopolysaccharide biosynthesis protein walW - - - - - - - - - - - - k141_3631_1 1288826.MSNKSG1_11548 2.95e-123 358.0 COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,466V6@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily astE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009017,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_813,iECABU_c1320.ECABU_c20010,iECED1_1282.ECED1_1946,iECOK1_1307.ECOK1_1864,iECS88_1305.ECS88_1796,iUMN146_1321.UM146_08430,iUTI89_1310.UTI89_C1939,ic_1306.c2144 AstE_AspA k141_14083_1 1278309.KB907099_gene2652 2.95e-190 537.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RZJ1@1236|Gammaproteobacteria,1XIDA@135619|Oceanospirillales 135619|Oceanospirillales C Quinohemoprotein amine dehydrogenase - - - - - - - - - - - - Fer4_12,Radical_SAM k141_11323_1 1232437.KL662058_gene3963 5.6e-13 72.8 COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1N9PE@1224|Proteobacteria,42Z0B@68525|delta/epsilon subdivisions,2WUJ2@28221|Deltaproteobacteria,2MMQ0@213118|Desulfobacterales 28221|Deltaproteobacteria T PAS fold - - - - - - - - - - - - PAS_4 k141_7824_1 396588.Tgr7_0851 2.5e-62 213.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X09E@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_19650_1 866536.Belba_3829 3.7e-79 256.0 COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,47JK7@768503|Cytophagia 976|Bacteroidetes J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_16150_1 488538.SAR116_2106 7.73e-18 81.3 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2TTE2@28211|Alphaproteobacteria,4BPV1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain ttrB - - ko:K00124,ko:K21308 ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200 - R00519,R11487 RC00168,RC02796 ko00000,ko00001 - - - Fer4_11,Fer4_3,Fer4_4 k141_16150_2 883080.HMPREF9697_03727 5.76e-43 150.0 COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2TUQ5@28211|Alphaproteobacteria,3K2FH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DMSO reductase anchor subunit (DmsC) dmsC - - ko:K21309 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 - - - DmsC k141_6396_1 452471.Aasi_0303 3.53e-48 167.0 COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia 976|Bacteroidetes U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_16870_2 1238190.AMQY01000021_gene1539 4.5e-25 102.0 COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales 135619|Oceanospirillales L HTH-like domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_14792_1 1382356.JQMP01000001_gene971 1.11e-11 65.9 COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,27XHM@189775|Thermomicrobia 189775|Thermomicrobia F Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - - - - - - - - - - ATP-grasp_4 k141_14792_2 1230342.CTM_22481 1.16e-20 92.8 COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,36EV6@31979|Clostridiaceae 186801|Clostridia C Radical SAM domain protein - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_841_2 440512.C211_14391 1.74e-21 94.4 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9,dCache_3 k141_4323_1 998674.ATTE01000001_gene829 4.99e-61 194.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S4BP@1236|Gammaproteobacteria,462AP@72273|Thiotrichales 72273|Thiotrichales O Hsp20/alpha crystallin family - - - - - - - - - - - - HSP20 k141_9873_1 999550.KI421507_gene1360 2.2e-69 231.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_5742_1 351016.RAZWK3B_04640 1.37e-63 199.0 COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2P1PC@2433|Roseobacter 28211|Alphaproteobacteria O COG0694 Thioredoxin-like proteins and domains nifU - - - - - - - - - - - Nfu_N,NifU k141_2926_1 1123517.JOMR01000001_gene1293 2.99e-84 275.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales 72273|Thiotrichales F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_7107_1 631362.Thi970DRAFT_02777 7.43e-92 300.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X2T8@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,Response_reg k141_21733_1 386456.JQKN01000001_gene2174 3.16e-11 68.2 COG0392@1|root,arCOG00899@2157|Archaea,2XUZK@28890|Euryarchaeota 28890|Euryarchaeota S integral membrane protein - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_21733_2 640081.Dsui_3445 3.45e-59 206.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VN72@28216|Betaproteobacteria,2KU7A@206389|Rhodocyclales 206389|Rhodocyclales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - ko:K00786 - - - - ko00000,ko01000 - - - PMT_2 k141_10627_1 555778.Hneap_0689 8.06e-67 208.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1WZ06@135613|Chromatiales 135613|Chromatiales S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 k141_17574_1 1317118.ATO8_14397 2.12e-83 263.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,4KKSK@93682|Roseivivax 28211|Alphaproteobacteria J The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_14805_1 1288826.MSNKSG1_12107 4.95e-166 471.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_5003_1 270374.MELB17_08331 6.72e-37 145.0 28V5F@1|root,2ZH8Q@2|Bacteria,1NKSZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_16169_1 1288826.MSNKSG1_11748 6.52e-96 306.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_16169_2 1288826.MSNKSG1_11743 1.66e-88 261.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,466V2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_9884_1 400682.PAC_15711222 2.23e-24 95.5 COG0316@1|root,KOG1120@2759|Eukaryota 2759|Eukaryota C protein maturation by iron-sulfur cluster transfer - GO:0003674,GO:0005198,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - ko:K22063 - - - - ko00000,ko03029 - - - Fe-S_biosyn k141_9884_2 1469245.JFBG01000021_gene1196 1.49e-93 293.0 COG0151@1|root,COG0151@2|Bacteria,1QTYI@1224|Proteobacteria 1224|Proteobacteria F ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4 k141_12696_1 1278309.KB907100_gene2153 1.34e-65 209.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XHHT@135619|Oceanospirillales 135619|Oceanospirillales D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_12696_2 1278309.KB907100_gene2152 2.94e-181 507.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1XI5W@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_12696_3 1278309.KB907100_gene2151 1.25e-28 105.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1XM1T@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF423 k141_10628_1 367336.OM2255_12872 3.47e-94 288.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K03732,ko:K11927 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_21120_1 1278309.KB907101_gene761 5.29e-143 433.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XI88@135619|Oceanospirillales 135619|Oceanospirillales C FAD-linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_11344_1 396588.Tgr7_2136 1.04e-39 134.0 COG4831@1|root,COG4831@2|Bacteria,1NMBS@1224|Proteobacteria,1SHJI@1236|Gammaproteobacteria,1X1V5@135613|Chromatiales 135613|Chromatiales S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_20401_1 1348114.OM33_12830 5.18e-139 398.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,2PZJ1@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_20401_2 395493.BegalDRAFT_0016 2.96e-23 101.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,45ZMI@72273|Thiotrichales 72273|Thiotrichales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_18981_1 1163617.SCD_n02039 0.0 1045.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria 28216|Betaproteobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_21734_1 357804.Ping_2759 2.21e-38 141.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon hdfR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HTH_1,LysR_substrate k141_17575_1 443152.MDG893_16522 2.57e-80 251.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,469VP@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein involved in benzoate metabolism benE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_7126_1 1049564.TevJSym_au00160 5.84e-182 525.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_18272_1 472759.Nhal_2771 2.81e-276 785.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales 135613|Chromatiales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_2942_1 1288494.EBAPG3_19700 3.14e-119 357.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,372VF@32003|Nitrosomonadales 28216|Betaproteobacteria C PFAM FAD dependent oxidoreductase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_19672_1 1122201.AUAZ01000018_gene1654 2.6e-88 263.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,4658G@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Fer2_3,Fer4_17,Fer4_8 k141_19672_2 1278309.KB907101_gene539 2.37e-88 276.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XIK9@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_3644_1 1278309.KB907101_gene410 1.73e-115 338.0 COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,1S589@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q 2-keto-4-pentenoate hydratase - - 4.2.1.80 ko:K02554 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R02601,R04781 RC00750,RC01213 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_3644_2 666681.M301_1418 5.78e-20 92.0 COG0404@1|root,COG0404@2|Bacteria,1N2I3@1224|Proteobacteria,2VVMU@28216|Betaproteobacteria,2KMXD@206350|Nitrosomonadales 206350|Nitrosomonadales E Sarcosine oxidase, gamma subunit family - - 1.5.3.1 ko:K00305 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxG k141_3644_3 491952.Mar181_2503 6.81e-222 642.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,1XIC3@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the GcvT family - - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_127_1 283942.IL0831 1.07e-97 295.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,2QF0G@267893|Idiomarinaceae 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain yqjG - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_127_2 314345.SPV1_09418 2.76e-35 127.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria 1224|Proteobacteria L Belongs to the pirin family yhhW_2 - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_8514_1 1323663.AROI01000023_gene1500 1.08e-140 405.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_8514_2 1323663.AROI01000023_gene1499 2.5e-111 328.0 COG1028@1|root,COG1028@2|Bacteria,1R48C@1224|Proteobacteria,1SPF8@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_8514_3 1323663.AROI01000023_gene1498 1.53e-120 350.0 COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,1SP19@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ short chain dehydrogenase reductase family - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_13412_1 1278309.KB907100_gene2349 2.92e-163 465.0 COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,1RRBY@1236|Gammaproteobacteria,1XIJA@135619|Oceanospirillales 135619|Oceanospirillales S membrane protein, required for spore maturation in B.subtilis - - - - - - - - - - - - Gate k141_13412_2 1278309.KB907100_gene2350 4.03e-304 844.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales 135619|Oceanospirillales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_14109_1 1168067.JAGP01000001_gene1864 6.7e-34 125.0 28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,1S9ED@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7127_1 317025.Tcr_2158 2.69e-25 102.0 COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,1S6P0@1236|Gammaproteobacteria,462TC@72273|Thiotrichales 72273|Thiotrichales S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_3645_1 309801.trd_0913 1.21e-55 188.0 COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,27XHM@189775|Thermomicrobia 189775|Thermomicrobia F Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - - - - - - - - - - ATP-grasp_4 k141_1545_1 1123400.KB904780_gene1904 2.05e-51 181.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3 k141_21735_1 1446473.JHWH01000016_gene2330 3.6e-27 102.0 COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,2U728@28211|Alphaproteobacteria,2PWWZ@265|Paracoccus 28211|Alphaproteobacteria E Glyoxalase-like domain mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 k141_21735_2 1188256.BASI01000003_gene2821 9.93e-62 213.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,3FCQB@34008|Rhodovulum 28211|Alphaproteobacteria G Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_15527_2 765913.ThidrDRAFT_0959 9.8e-59 184.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S4NM@1236|Gammaproteobacteria,1WYNU@135613|Chromatiales 135613|Chromatiales KT response regulator receiver - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_15527_3 930166.CD58_11830 8.16e-13 66.2 COG1366@1|root,COG1366@2|Bacteria,1N8B6@1224|Proteobacteria,1SGMB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T transporter antisigma-factor antagonist STAS - - - - - - - - - - - - STAS_2 k141_15527_4 1123255.JHYS01000005_gene647 1.33e-69 234.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,4ACKZ@80864|Comamonadaceae 28216|Betaproteobacteria NT Signal transducing histidine kinase, homodimeric domain - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_17577_2 1392540.P256_01500 1.9e-12 67.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,3NJB6@468|Moraxellaceae 1236|Gammaproteobacteria P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 BPD_transp_1 k141_18273_1 396588.Tgr7_3122 5.36e-84 255.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1WW8S@135613|Chromatiales 135613|Chromatiales S PFAM conserved - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_18273_2 1198452.Jab_2c25430 7.34e-07 51.6 COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,4748P@75682|Oxalobacteraceae 28216|Betaproteobacteria O Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124,Glutaredoxin k141_12698_1 1163617.SCD_n01613 6.93e-78 251.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria 28216|Betaproteobacteria P Ferrous iron transport protein B feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_6414_2 322710.Avin_12810 1.98e-26 105.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA k141_6414_3 1123053.AUDG01000004_gene3468 1.08e-17 79.7 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1WW0D@135613|Chromatiales 135613|Chromatiales S PFAM ABC transporter - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_4343_1 1201290.M902_3288 3.1e-53 177.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2MT0Z@213481|Bdellovibrionales,2WMRQ@28221|Deltaproteobacteria 213481|Bdellovibrionales M peptidylprolyl isomerase, FKBP-type - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_4343_2 1122917.KB899666_gene3474 4.97e-08 56.6 COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,4HFCI@91061|Bacilli,2771J@186822|Paenibacillaceae 91061|Bacilli Q Polyketide synthase modules and related proteins - - - - - - - - - - - - AMP-binding,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt k141_5005_1 1226994.AMZB01000109_gene1738 4.49e-77 244.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1YEGQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_5005_2 243924.LT42_20875 6.2e-46 162.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_12131_1 1395571.TMS3_0111740 2.25e-62 201.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria 1236|Gammaproteobacteria T chemotaxis signal transduction protein cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_14209_1 644801.Psest_1018 3.35e-72 227.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1Z1NN@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Methylates ribosomal protein L11 prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_14209_2 400668.Mmwyl1_2984 4.4e-11 67.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1XKK2@135619|Oceanospirillales 135619|Oceanospirillales S MJ0042 family finger-like protein - - - - - - - - - - - - DUF3426,zinc_ribbon_5 k141_1699_1 396588.Tgr7_3233 1.08e-52 170.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,1SAXA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P belongs to the Fur family - - - ko:K09826 - - - - ko00000,ko03000 - - - FUR k141_4493_1 591023.AM202_05614 1.02e-13 69.7 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1Y7NI@135625|Pasteurellales 135625|Pasteurellales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_4493_2 754477.Q7C_417 1.25e-38 138.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,45ZSI@72273|Thiotrichales 72273|Thiotrichales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_17723_1 713586.KB900536_gene182 9.39e-17 82.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SGPC@1236|Gammaproteobacteria,1WYNC@135613|Chromatiales 135613|Chromatiales T PFAM Anti sigma-E protein RseA - - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_N k141_7983_1 1278309.KB907103_gene1164 2.8e-252 709.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XHDQ@135619|Oceanospirillales 135619|Oceanospirillales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_7983_2 1278309.KB907103_gene1163 2.65e-140 403.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XHH6@135619|Oceanospirillales 135619|Oceanospirillales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF-1 - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_3764_1 748247.AZKH_p0092 3.93e-18 81.3 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,2KXVY@206389|Rhodocyclales 206389|Rhodocyclales S Haemolysin-III related - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_3764_2 1163617.SCD_n00692 6.84e-138 398.0 COG0224@1|root,COG0224@2|Bacteria,1N4GR@1224|Proteobacteria,2VJRE@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM H transporting two-sector ATPase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_3764_3 1163617.SCD_n00693 2.58e-219 619.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2VPGJ@28216|Betaproteobacteria 28216|Betaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA2 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_11444_1 768671.ThimaDRAFT_2910 2.98e-62 192.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1WYFA@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_19784_1 1278309.KB907100_gene2351 3.05e-77 238.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,1XIP1@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH k141_19784_2 1278309.KB907100_gene2352 1.14e-47 154.0 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1XMD2@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_19784_3 1278309.KB907100_gene2353 2.45e-83 269.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales 135619|Oceanospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_975_1 1157708.KB907451_gene4874 3.46e-17 87.8 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae 28216|Betaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin PilY1-like protein - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_19131_1 32057.KB217478_gene2327 2.93e-29 113.0 COG2717@1|root,COG2717@2|Bacteria,1GMZR@1117|Cyanobacteria,1HS54@1161|Nostocales 1117|Cyanobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - - - - - - - - - - - k141_19131_2 519989.ECTPHS_00605 3.86e-10 56.2 COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional - - - - - - - - - - - - AsnC_trans_reg k141_21237_1 83406.HDN1F_18810 5.8e-18 90.1 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,1J70G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13511_2 2340.JV46_29040 3.59e-51 176.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1J4T7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iPC815.YPO3762,iSFV_1184.SFV_3651 TrkH k141_16272_1 1232683.ADIMK_0165 1.06e-51 176.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,463YB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_9991_1 1158150.KB906243_gene1650 8.54e-42 151.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_9991_2 595494.Tola_0774 4.09e-43 145.0 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1Y5WJ@135624|Aeromonadales 135624|Aeromonadales S Phosphate-starvation-inducible E - - - ko:K13256 - - - - ko00000 - - - PsiE k141_9305_2 1348635.BBJY01000014_gene789 2.38e-60 199.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XVHW@135623|Vibrionales 135623|Vibrionales E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_2336_1 555778.Hneap_1356 7.89e-41 141.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1WX8T@135613|Chromatiales 135613|Chromatiales K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_2336_2 1049564.TevJSym_bn00090 1.21e-50 176.0 COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,1RQAX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Periplasmic protein TonB links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_12831_1 1288826.MSNKSG1_17950 6.73e-152 441.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,46485@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N k141_12831_2 1288826.MSNKSG1_17955 4.81e-274 752.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,464EE@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretory pathway, component PulF mshG - - ko:K02505,ko:K12278 - - - - ko00000,ko02044 - - - T2SSF k141_1700_2 38833.XP_003056973.1 1.31e-06 50.8 COG0790@1|root,KOG1550@2759|Eukaryota,37R69@33090|Viridiplantae 33090|Viridiplantae MOT F-box protein - - - - - - - - - - - - F-box,Sel1 k141_7984_1 1410620.SHLA_8c000260 9.8e-100 302.0 COG1653@1|root,COG1653@2|Bacteria,1QUAI@1224|Proteobacteria,2TXVM@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 k141_10765_1 316275.VSAL_II0165 6.06e-74 229.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XUA3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_10765_2 697282.Mettu_1570 5.82e-53 169.0 COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,1XFB1@135618|Methylococcales 135618|Methylococcales K Nitrogen regulatory protein P-II - - - - - - - - - - - - - k141_10765_3 697282.Mettu_1569 7.82e-48 156.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XF65@135618|Methylococcales 135618|Methylococcales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_5135_1 1278309.KB907101_gene600 2.05e-131 387.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1XH2B@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_5135_2 1278309.KB907101_gene599 1.23e-214 601.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1XJ2H@135619|Oceanospirillales 135619|Oceanospirillales T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9 k141_16996_1 1278309.KB907105_gene1427 0.0 1076.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XI30@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_3766_1 396595.TK90_2032 6.58e-103 322.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales 135613|Chromatiales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_976_1 388401.RB2150_07703 1.28e-68 214.0 COG1396@1|root,COG1396@2|Bacteria,1RJG9@1224|Proteobacteria,2U8MZ@28211|Alphaproteobacteria,3ZHCA@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria K transcriptional regulators - - - - - - - - - - - - Cupin_2,HTH_31 k141_12133_1 1123296.JQKE01000007_gene485 1.19e-09 58.9 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,2KQ5U@206351|Neisseriales 206351|Neisseriales S LysM domain protein - - - - - - - - - - - - LysM k141_12133_2 926554.KI912633_gene4039 8.36e-49 177.0 COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg k141_15617_1 1177181.T9A_01856 2.3e-67 219.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_6504_1 1288826.MSNKSG1_00968 7.24e-112 321.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,467C1@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_6504_2 1288826.MSNKSG1_00963 2.85e-194 541.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1S4KX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive Ion channel - - - - - - - - - - - - MS_channel k141_6504_3 1288826.MSNKSG1_00958 9.48e-164 459.0 COG2430@1|root,COG2430@2|Bacteria,1REND@1224|Proteobacteria,1S94F@1236|Gammaproteobacteria,4681T@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF432 k141_273_1 1026882.MAMP_01496 1.46e-87 266.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,4624P@72273|Thiotrichales 72273|Thiotrichales P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_21896_1 1278309.KB907101_gene323 3.34e-187 550.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH4Q@135619|Oceanospirillales 135619|Oceanospirillales V efflux pump - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_21896_2 1278309.KB907101_gene324 5.15e-140 405.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XK08@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_17724_1 1322246.BN4_11959 6.19e-43 157.0 COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WPR9@28221|Deltaproteobacteria,2M7TV@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM Metal-dependent hydrolase HDOD - - - - - - - - - - - - HDOD k141_17724_2 693444.D782_0933 4.24e-51 169.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C nucleoside triphosphate pyrophosphohydrolase mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 MazG k141_9992_1 1349785.BAUG01000005_gene424 5.05e-05 45.8 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia 976|Bacteroidetes M Lytic murein transglycosylase mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_9992_2 1317122.ATO12_22025 1.01e-20 97.8 COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,1HYAV@117743|Flavobacteriia,2YI0Q@290174|Aquimarina 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 k141_19785_1 153948.NAL212_1204 3.07e-69 225.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,372RT@32003|Nitrosomonadales 28216|Betaproteobacteria O PFAM Magnesium chelatase, ChlI subunit comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_20545_1 519989.ECTPHS_08443 1.25e-42 160.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_16273_1 519989.ECTPHS_08316 2.25e-54 182.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1WXW8@135613|Chromatiales 135613|Chromatiales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_21238_1 1121004.ATVC01000046_gene820 9.72e-40 154.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KQ5R@206351|Neisseriales 206351|Neisseriales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_7257_1 754476.Q7A_1267 1.04e-34 124.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,4604Q@72273|Thiotrichales 72273|Thiotrichales D TIGRFAM Cell division ATP-binding protein FtsE - - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_7257_2 1122212.AULO01000012_gene1013 6.15e-94 290.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XHHT@135619|Oceanospirillales 135619|Oceanospirillales D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_7257_3 395493.BegalDRAFT_2669 3.39e-137 408.0 COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,1NEBU@1224|Proteobacteria,1RYA6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T response regulator - - - - - - - - - - - - Response_reg k141_7257_4 1279015.KB908458_gene2566 5.99e-35 127.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1Y3I9@135624|Aeromonadales 135624|Aeromonadales K RNA polymerase sigma rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_5856_1 1288826.MSNKSG1_15951 1.74e-191 535.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,465F2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k141_5856_2 1288826.MSNKSG1_15956 9.48e-193 534.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1S2YF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates - - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_3109_1 396588.Tgr7_2948 1.98e-33 134.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales 135613|Chromatiales M PFAM AsmA family protein - - - ko:K07289 - - - - ko00000 - - - AsmA k141_19148_1 216432.CA2559_12918 1.38e-06 51.2 COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1I23F@117743|Flavobacteriia 976|Bacteroidetes M Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 k141_19148_2 1237149.C900_03472 7.38e-19 80.5 COG4980@1|root,COG4980@2|Bacteria,4NVHP@976|Bacteroidetes,47RXK@768503|Cytophagia 976|Bacteroidetes S YtxH-like protein - - - - - - - - - - - - YtxH k141_1711_1 1294273.roselon_00362 1.16e-62 205.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TTQ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_5153_1 1121878.AUGL01000024_gene3721 6.1e-73 234.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0050896,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_21249_1 368407.Memar_1955 7.65e-17 79.0 COG0500@1|root,arCOG01783@2157|Archaea,2XV4B@28890|Euryarchaeota,2NAR8@224756|Methanomicrobia 224756|Methanomicrobia Q Putative methyltransferase - - - - - - - - - - - - - k141_21249_2 95619.PM1_0209665 1.25e-43 150.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k141_8015_2 1111728.ATYS01000016_gene4665 4.66e-12 62.8 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775 ThiS k141_8015_3 1249627.D779_0329 1.71e-32 117.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1WY7V@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_10015_1 1288826.MSNKSG1_12557 6.28e-39 138.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,46ADB@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4175 ABC-type proline glycine betaine transport system, ATPase component - - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_10015_2 1288826.MSNKSG1_12562 7.25e-25 100.0 COG0834@1|root,COG0834@2|Bacteria,1RI5R@1224|Proteobacteria,1S5PV@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_5875_1 765913.ThidrDRAFT_0189 4.3e-43 153.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_5875_2 395493.BegalDRAFT_0708 3.03e-74 243.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales 72273|Thiotrichales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_8643_1 1231391.AMZF01000069_gene2119 4.87e-36 135.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,3T1UE@506|Alcaligenaceae 28216|Betaproteobacteria M Belongs to the peptidase S11 family dacC - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_8643_2 207954.MED92_07701 9.41e-78 243.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XIEE@135619|Oceanospirillales 135619|Oceanospirillales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k141_17744_1 1121921.KB898706_gene2713 5.24e-35 131.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,2PMP4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_17744_2 1123020.AUIE01000013_gene138 6.42e-09 59.3 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SDJY@1236|Gammaproteobacteria,1YGCK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 k141_17744_3 1122139.KB907879_gene2894 1.08e-15 75.1 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1XIMD@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_19790_1 713586.KB900536_gene2658 1.34e-105 316.0 COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales 135613|Chromatiales L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - - k141_19790_2 1231190.NA8A_10128 2.92e-127 413.0 COG0457@1|root,COG0846@1|root,COG0457@2|Bacteria,COG0846@2|Bacteria,1PM9Y@1224|Proteobacteria,2UZX3@28211|Alphaproteobacteria,43QKY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K SIR2-like domain - - - - - - - - - - - - SIR2_2 k141_20562_2 765912.Thimo_0969 2.27e-57 189.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1WX92@135613|Chromatiales 135613|Chromatiales D probably involved in intracellular septation - - - ko:K06190 - - - - ko00000 - - - IspA k141_20562_3 1211112.ALJC01000138_gene2615 1.65e-51 164.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria 1236|Gammaproteobacteria T YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05527,ko:K09780 - - - - ko00000,ko03000 - - - YCII k141_19258_1 1218084.BBJK01000059_gene4516 4.72e-12 67.8 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae 28216|Betaproteobacteria T GGDEF domain containing protein - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MHYT k141_15011_1 1123228.AUIH01000003_gene834 1.66e-93 280.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XHIU@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_10132_1 317025.Tcr_0033 8.42e-80 249.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,461TG@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 k141_10132_2 426114.THI_3216 1.18e-08 57.4 COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,1MUDV@1224|Proteobacteria,2VHKA@28216|Betaproteobacteria,1KN0F@119065|unclassified Burkholderiales 28216|Betaproteobacteria P C-terminal AAA-associated domain - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran k141_15749_1 1005048.CFU_3254 5.41e-20 87.8 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,472TH@75682|Oxalobacteraceae 28216|Betaproteobacteria G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gap GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_15749_2 1278309.KB907101_gene809 2.79e-46 156.0 COG1196@1|root,COG1196@2|Bacteria,1N4Q4@1224|Proteobacteria,1SAM5@1236|Gammaproteobacteria,1XMGU@135619|Oceanospirillales 135619|Oceanospirillales D Plasmid replication region DNA-binding N-term - - - - - - - - - - - - KfrA_N k141_1107_1 45351.EDO45616 1.06e-06 58.9 COG4805@1|root,2QUES@2759|Eukaryota,39R27@33154|Opisthokonta 33154|Opisthokonta S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 k141_13634_1 1278309.KB907104_gene918 7.47e-55 174.0 COG0607@1|root,COG0607@2|Bacteria,1N70J@1224|Proteobacteria,1SE5K@1236|Gammaproteobacteria,1XMBQ@135619|Oceanospirillales 135619|Oceanospirillales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_13634_2 1278309.KB907104_gene920 4.97e-102 300.0 COG2885@1|root,COG2885@2|Bacteria,1N4RD@1224|Proteobacteria,1S9YV@1236|Gammaproteobacteria,1XRJM@135619|Oceanospirillales 135619|Oceanospirillales M COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - - - - - - - - - - OmpA k141_13634_3 1479235.KK366039_gene2953 2.39e-49 158.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1XKEK@135619|Oceanospirillales 135619|Oceanospirillales S YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the yciI - - ko:K09780 - - - - ko00000 - - - YCII k141_13634_4 1278309.KB907104_gene922 9.86e-115 330.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1XJ5X@135619|Oceanospirillales 135619|Oceanospirillales D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA k141_13634_5 1278309.KB907104_gene923 5.22e-167 471.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1XJX3@135619|Oceanospirillales 135619|Oceanospirillales S metal-dependent phosphoesterases (PHP family) - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_13634_6 1278309.KB907104_gene924 6.92e-136 385.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1XHKV@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the SUA5 family - - - - - - - - - - - - Sua5_yciO_yrdC k141_13634_7 207954.MED92_16250 8.86e-47 154.0 COG2916@1|root,COG2916@2|Bacteria,1R9YM@1224|Proteobacteria,1S24H@1236|Gammaproteobacteria,1XKQK@135619|Oceanospirillales 135619|Oceanospirillales K H-NS histone family - - - - - - - - - - - - Histone_HNS k141_13634_8 1278309.KB907104_gene926 6.34e-174 488.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1XH71@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_13634_9 1278309.KB907104_gene927 2.27e-145 413.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1XH47@135619|Oceanospirillales 135619|Oceanospirillales IQ reductase - - - - - - - - - - - - adh_short k141_13634_10 1278309.KB907104_gene928 4.38e-117 340.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1XJMU@135619|Oceanospirillales 135619|Oceanospirillales S haloacid dehalogenase-like hydrolase gph - 3.1.3.105 ko:K22292 ko00520,map00520 - R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_13634_11 1278309.KB907104_gene929 1.72e-158 446.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XH4S@135619|Oceanospirillales 135619|Oceanospirillales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 k141_11546_1 1278309.KB907113_gene3319 1.22e-56 178.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales 135619|Oceanospirillales U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_8736_1 713586.KB900536_gene1783 1.07e-74 248.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k141_4593_1 765914.ThisiDRAFT_1433 6.7e-87 266.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_8130_1 1137799.GZ78_27770 2.53e-127 386.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XHUH@135619|Oceanospirillales 135619|Oceanospirillales C Isocitrate dehydrogenase - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_19882_1 1278309.KB907105_gene1401 6.3e-185 522.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XHBS@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_19882_2 1278309.KB907105_gene1400 1.05e-243 690.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1XI7D@135619|Oceanospirillales 135619|Oceanospirillales H COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_6,TPR_8 k141_19882_3 1278309.KB907105_gene1399 1.35e-97 288.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1XKNX@135619|Oceanospirillales 135619|Oceanospirillales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB k141_19882_4 1278309.KB907105_gene1398 6.5e-218 603.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1XI6V@135619|Oceanospirillales 135619|Oceanospirillales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_19882_5 1278309.KB907105_gene1397 7.32e-111 322.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XJNP@135619|Oceanospirillales 135619|Oceanospirillales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_19882_6 1278309.KB907105_gene1396 1.36e-133 379.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XJ8C@135619|Oceanospirillales 135619|Oceanospirillales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_19882_7 1278309.KB907105_gene1395 5.22e-237 654.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1XH6C@135619|Oceanospirillales 135619|Oceanospirillales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_12268_1 666509.RCA23_c11990 8.41e-96 283.0 COG0410@1|root,COG0410@2|Bacteria,1R8FA@1224|Proteobacteria,2U0JB@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_12268_2 666509.RCA23_c12000 5.23e-117 338.0 COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_9405_2 398512.JQKC01000002_gene1900 2.66e-62 204.0 COG0535@1|root,COG0535@2|Bacteria,1VBU3@1239|Firmicutes,25M2V@186801|Clostridia,3WM5Z@541000|Ruminococcaceae 186801|Clostridia C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k141_15759_1 314278.NB231_15233 6.22e-109 317.0 COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,1RXZV@1236|Gammaproteobacteria,1WWCC@135613|Chromatiales 135613|Chromatiales CQ BMC - - - - - - - - - - - - BMC k141_13654_1 439235.Dalk_1463 9.6e-97 291.0 COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales 28221|Deltaproteobacteria L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3,HTH_32 k141_5286_1 349124.Hhal_1007 2.78e-17 77.8 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales 135613|Chromatiales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_5286_2 395493.BegalDRAFT_1662 4.98e-64 206.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,460NI@72273|Thiotrichales 72273|Thiotrichales M Involved in formation and maintenance of cell shape - - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_3860_2 545264.KB898746_gene986 2.54e-53 170.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,1SJ46@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 k141_3860_3 269796.Rru_A2630 3.37e-94 285.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,2JQ4F@204441|Rhodospirillales 204441|Rhodospirillales GK ROK family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_10146_2 870187.Thini_1174 3.85e-103 306.0 COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,1T3H0@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_7364_1 519989.ECTPHS_00974 4.72e-30 107.0 COG0361@1|root,COG0361@2|Bacteria 2|Bacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a k141_16397_1 1537917.JU82_07460 2.46e-36 133.0 COG0859@1|root,COG0859@2|Bacteria,1NTHI@1224|Proteobacteria 1224|Proteobacteria M lipopolysaccharide biosynthesis protein - - - - - - - - - - - - Glyco_transf_9 k141_8745_1 388467.A19Y_0188 2.19e-53 182.0 COG1070@1|root,COG1070@2|Bacteria,1G0G6@1117|Cyanobacteria,1H9JM@1150|Oscillatoriales 1117|Cyanobacteria G PFAM FGGY family of carbohydrate kinases, N-terminal domain xylB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019150,GO:0019200,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_15026_1 153721.MYP_4405 5.73e-92 287.0 COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia 976|Bacteroidetes L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_17106_1 1396858.Q666_04015 1.12e-37 133.0 COG3637@1|root,COG3637@2|Bacteria,1NC7F@1224|Proteobacteria,1SF4E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M OmpA-like transmembrane domain - - - - - - - - - - - - OmpA_membrane k141_9406_1 1168067.JAGP01000001_gene586 1.22e-91 290.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,4607W@72273|Thiotrichales 72273|Thiotrichales M sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_3225_1 1380394.JADL01000008_gene3606 6.34e-87 268.0 COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2TU8Z@28211|Alphaproteobacteria,2JRT0@204441|Rhodospirillales 204441|Rhodospirillales P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_3225_2 748247.AZKH_4488 3.37e-27 103.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2WHPH@28216|Betaproteobacteria,2KZ5U@206389|Rhodocyclales 206389|Rhodocyclales S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_13655_1 396588.Tgr7_0025 7.13e-81 250.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_1123_1 388401.RB2150_09204 2.39e-72 231.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2TT30@28211|Alphaproteobacteria,3ZI3R@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 fdnI - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB k141_11551_1 472759.Nhal_3111 4.27e-79 251.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1WWAI@135613|Chromatiales 135613|Chromatiales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_11551_2 2340.JV46_05560 5.33e-108 322.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1J4WT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_15760_1 886377.Murru_0790 2.01e-13 71.2 COG4659@1|root,COG4659@2|Bacteria,4NPUB@976|Bacteroidetes,1I2MB@117743|Flavobacteriia 976|Bacteroidetes C FMN_bind - - - - - - - - - - - - FMN_bind k141_17847_1 493475.GARC_3746 3.08e-15 72.0 COG2944@1|root,COG2944@2|Bacteria,1N0M9@1224|Proteobacteria,1T0CA@1236|Gammaproteobacteria,46D0N@72275|Alteromonadaceae 1236|Gammaproteobacteria K Antitoxin component of bacterial toxin-antitoxin system, MqsA - - - ko:K07726 - - - - ko00000,ko03000 - - - MqsA_antitoxin k141_5954_1 880073.Calab_3252 1.94e-29 121.0 COG3023@1|root,COG3023@2|Bacteria 2|Bacteria V N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,LysM,fn3 k141_7365_1 1288826.MSNKSG1_06233 2.4e-141 407.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,464DX@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_20640_1 1049564.TevJSym_av00430 9.1e-136 397.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1J4CI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM k141_13656_1 1049564.TevJSym_ak00380 2.45e-92 291.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1J572@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Oligopeptidase A prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_10147_2 1449976.KALB_3702 5.51e-05 47.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4E0XN@85010|Pseudonocardiales 201174|Actinobacteria P PFAM Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Rhodanese k141_10882_2 1278309.KB907105_gene1430 1.05e-125 374.0 2ECZP@1|root,336WQ@2|Bacteria,1NBQI@1224|Proteobacteria,1SEN0@1236|Gammaproteobacteria,1XMT7@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10882_3 1278309.KB907105_gene1429 6.3e-25 98.2 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1XKDJ@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - ACP_PD k141_17848_1 1123237.Salmuc_02292 3.91e-73 233.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter gguA - 3.6.3.17 ko:K10548 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.5 - - ABC_tran k141_17848_2 1185766.DL1_20275 3.12e-08 54.7 COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2TR9B@28211|Alphaproteobacteria,2XP32@285107|Thioclava 28211|Alphaproteobacteria U Belongs to the binding-protein-dependent transport system permease family gguB GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0019321,GO:0031224,GO:0042732,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944 - ko:K10547 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.5 - - BPD_transp_2 k141_3861_1 509190.Cseg_3165 5.67e-21 93.2 28JTG@1|root,2ZTYG@2|Bacteria,1NI0X@1224|Proteobacteria,2U89K@28211|Alphaproteobacteria,2KH8Y@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k141_3861_2 1208323.B30_07131 7.15e-11 62.8 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Gene transfer agent - - - - - - - - - - - - GTA_TIM,Phage-tail_3 k141_16399_1 631362.Thi970DRAFT_03773 4.46e-44 155.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1WXR0@135613|Chromatiales 135613|Chromatiales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_15761_1 10756.DPOL_BPPH2 2.33e-05 53.1 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage 10239|Viruses S DNA polymerase type B, organellar and viral - GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039687,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k141_5288_1 1042375.AFPL01000008_gene3243 2.11e-20 89.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,468IU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_5288_2 1054213.HMPREF9946_01743 1.27e-58 185.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2JSBG@204441|Rhodospirillales 204441|Rhodospirillales C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 k141_19271_1 1288826.MSNKSG1_17945 1.96e-38 139.0 COG0457@1|root,COG0457@2|Bacteria,1N8YE@1224|Proteobacteria,1RTI2@1236|Gammaproteobacteria,4699R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - ko:K12284 - - - - ko00000,ko02044 - - - TPR_16 k141_19271_2 1288826.MSNKSG1_17940 1.5e-114 333.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,465DA@72275|Alteromonadaceae 1236|Gammaproteobacteria U Type II secretory pathway, component ExeA mshM - - ko:K12283 - - - - ko00000,ko02044 - - - AAA_22 k141_8746_1 1205908.AKXW01000111_gene1649 1.04e-26 108.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XUTM@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator hdfR - - - - - - - - - - - HTH_1,LysR_substrate k141_7366_1 765911.Thivi_1188 3.36e-31 115.0 28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria,1WY0Y@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_13657_1 1052684.PPM_1749 1.96e-61 194.0 COG0454@1|root,COG0456@2|Bacteria,1VAYG@1239|Firmicutes,4HKJE@91061|Bacilli,26X23@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_4 k141_4605_1 1280949.HAD_09955 4.82e-20 96.3 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,43XM4@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_3226_1 349521.HCH_00295 4e-76 257.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XJ59@135619|Oceanospirillales 135619|Oceanospirillales F Adenylate cyclase, class-I - - 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - Adenyl_cycl_N,Adenylate_cycl k141_1125_1 118163.Ple7327_1530 6.14e-65 204.0 COG0605@1|root,COG0605@2|Bacteria,1G0N2@1117|Cyanobacteria,3VIKQ@52604|Pleurocapsales 1117|Cyanobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_5438_2 493475.GARC_1719 1.25e-103 308.0 COG1028@1|root,COG1028@2|Bacteria,1R4D2@1224|Proteobacteria,1RQZA@1236|Gammaproteobacteria,469AX@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_3349_1 1288826.MSNKSG1_00621 7.28e-264 724.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,46552@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Ketoacyl-synt_C,ketoacyl-synt k141_3349_2 1288826.MSNKSG1_00616 9.74e-173 482.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,466GX@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases anr - - ko:K01420 - - - - ko00000,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding k141_3349_3 1288826.MSNKSG1_00611 1.22e-211 584.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1S1MF@1236|Gammaproteobacteria,468FS@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_3349_5 1288826.MSNKSG1_00601 2.92e-234 646.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,464PJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids dadX - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iWFL_1372.ECW_m1275,iYL1228.KPN_02308 Ala_racemase_C,Ala_racemase_N k141_3349_6 1288826.MSNKSG1_00596 2.01e-313 855.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,4657V@72275|Alteromonadaceae 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_7523_2 519989.ECTPHS_00425 1.58e-19 88.6 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_20720_1 545276.KB898724_gene1979 3.05e-128 373.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales 135613|Chromatiales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_16548_1 1042375.AFPL01000015_gene2205 1.86e-37 128.0 2C44J@1|root,333VN@2|Bacteria,1N6Q4@1224|Proteobacteria,1SERN@1236|Gammaproteobacteria,4689A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phenol hydroxylase subunit dmpK - - ko:K16249 ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220 M00548 R03560,R03608,R10042,R10043 RC00046,RC00490 ko00000,ko00001,ko00002 - - - Phenol_hyd_sub k141_16548_2 1278309.KB907108_gene1608 8.79e-40 145.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XRYT@135619|Oceanospirillales 135619|Oceanospirillales K Activator of aromatic catabolism - - - - - - - - - - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_14402_1 1198452.Jab_2c14690 4.74e-15 77.4 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,477PC@75682|Oxalobacteraceae 28216|Betaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03585,ko:K18306 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6 - - HlyD_D23 k141_14402_2 357808.RoseRS_2899 7.72e-68 218.0 COG0639@1|root,COG0639@2|Bacteria,2G71P@200795|Chloroflexi,375UU@32061|Chloroflexia 32061|Chloroflexia T PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos_2 k141_21479_1 768671.ThimaDRAFT_0369 3.05e-22 91.3 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales 135613|Chromatiales C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 k141_21479_2 713586.KB900536_gene2898 2.76e-86 266.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_1941_1 1185766.DL1_13020 3.04e-84 249.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2XN8Y@285107|Thioclava 28211|Alphaproteobacteria J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k141_18658_1 349124.Hhal_1478 3.59e-39 141.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales 135613|Chromatiales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_6084_1 1288826.MSNKSG1_05833 8.2e-153 433.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria,46682@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_1271_1 631362.Thi970DRAFT_03191 6.67e-129 377.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXRF@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase family 2 - - 2.4.2.53 ko:K10012,ko:K20534 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8,4.D.2.1.9 GT2 - Glycos_transf_2 k141_17246_1 1278309.KB907104_gene891 2.39e-80 248.0 COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,1S95Z@1236|Gammaproteobacteria,1XKQT@135619|Oceanospirillales 135619|Oceanospirillales M SprA-related family - - - - - - - - - - - - SprA-related k141_17246_2 1278309.KB907104_gene892 9.34e-100 294.0 COG0625@1|root,COG0625@2|Bacteria,1QEZP@1224|Proteobacteria,1S3EZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_3,GST_N k141_17246_3 1298593.TOL_1467 5.93e-14 70.9 COG3968@1|root,COG3968@2|Bacteria,1QDHB@1224|Proteobacteria,1RS3B@1236|Gammaproteobacteria,1XNV6@135619|Oceanospirillales 135619|Oceanospirillales S Glutamine synthetase type III N terminal - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C k141_13120_1 686340.Metal_0450 2.98e-34 129.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XDK1@135618|Methylococcales 135618|Methylococcales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_13120_2 351348.Maqu_1025 1.27e-15 77.8 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_8259_2 998674.ATTE01000001_gene2803 1.66e-27 113.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,45ZNZ@72273|Thiotrichales 72273|Thiotrichales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_548_1 472759.Nhal_2019 9.39e-227 649.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales 135613|Chromatiales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 k141_12443_1 998674.ATTE01000001_gene2757 8.49e-55 188.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales 72273|Thiotrichales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_12443_2 870187.Thini_4186 2.37e-09 58.5 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,460FP@72273|Thiotrichales 72273|Thiotrichales F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_7524_1 526118.B4YQF6_9CAUD 9.47e-22 97.1 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k141_10293_2 1121004.ATVC01000019_gene1843 5.53e-55 174.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,2KR67@206351|Neisseriales 206351|Neisseriales C Required for insertion of 4Fe-4S clusters erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_11671_1 1323663.AROI01000023_gene1493 5.4e-68 213.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria 1224|Proteobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_11671_2 1323663.AROI01000023_gene1494 1.36e-156 444.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQ0A@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_11671_3 1218352.B597_016410 7.94e-68 218.0 294MD@1|root,2ZS0U@2|Bacteria,1NEY7@1224|Proteobacteria,1SFSY@1236|Gammaproteobacteria,1Z1FX@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11671_4 1218352.B597_016405 2.35e-103 304.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1RQ26@1236|Gammaproteobacteria,1Z2MB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily attM - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B k141_9521_1 187272.Mlg_1890 5.77e-236 674.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales 135613|Chromatiales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_6085_1 1334046.AYTB01000007_gene3006 9.27e-15 77.4 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,26FJU@186818|Planococcaceae 91061|Bacilli M Transglycosylase SLT domain yjbJ - - - - - - - - - - - SLT k141_18659_1 1134474.O59_000790 2.15e-62 219.0 COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T5VJ@1236|Gammaproteobacteria,1FG2S@10|Cellvibrio 1236|Gammaproteobacteria T Double sensory domain of two-component sensor kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,dCache_3 k141_19380_1 1485544.JQKP01000012_gene2150 2.01e-70 240.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales 28216|Betaproteobacteria L Helicase associated domain (HA2) Add an annotation hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_1942_1 754477.Q7C_1107 4.65e-72 224.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,460RQ@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_1942_2 2340.JV46_10830 4.91e-15 72.8 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1J525@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfE - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_6086_1 247633.GP2143_04620 2.42e-27 109.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1J5AN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_4758_1 1380387.JADM01000011_gene3598 7.18e-99 318.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1XID1@135619|Oceanospirillales 135619|Oceanospirillales EI carboxylase uahA - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_22142_1 1278309.KB907105_gene1515 1.67e-71 223.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XHIQ@135619|Oceanospirillales 135619|Oceanospirillales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_22142_2 1278309.KB907105_gene1516 1.81e-114 329.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1XJ7F@135619|Oceanospirillales 135619|Oceanospirillales L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn - - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_22142_3 1278309.KB907105_gene1517 4.09e-12 66.2 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XH59@135619|Oceanospirillales 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_549_1 1049564.TevJSym_at00260 2.4e-122 365.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N k141_13122_1 1278309.KB907101_gene494 2.78e-52 181.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,1XIKP@135619|Oceanospirillales 135619|Oceanospirillales E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 k141_13122_2 1278309.KB907101_gene495 7.36e-13 65.5 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1XJBH@135619|Oceanospirillales 135619|Oceanospirillales P Zn-ribbon-containing protein involved in phosphonate metabolism - - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_5439_1 1122599.AUGR01000014_gene652 1.61e-64 200.0 COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria,1S2H9@1236|Gammaproteobacteria,1XJMX@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_5439_2 1278309.KB907100_gene2198 7.84e-202 562.0 COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,1RQG9@1236|Gammaproteobacteria,1XHPC@135619|Oceanospirillales 135619|Oceanospirillales G TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_6730_1 1280953.HOC_11982 5.06e-54 206.0 COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria 1224|Proteobacteria EHJ outer membrane autotransporter barrel domain - - - ko:K12678 - - - - ko00000,ko02000,ko02044 1.B.12.1.1,1.B.12.1.3 - - Autotransporter,ESPR,PATR,Pertactin k141_15141_1 1278309.KB907099_gene2408 6.01e-129 376.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1XJMJ@135619|Oceanospirillales 135619|Oceanospirillales P protein involved in response to NO nnrS - - ko:K07234 - - - - ko00000 - - - NnrS k141_15141_2 1278309.KB907099_gene2409 1.19e-153 438.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1XJ2T@135619|Oceanospirillales 135619|Oceanospirillales P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k141_15141_3 1278309.KB907099_gene2410 9.35e-47 151.0 2ER3J@1|root,33IP6@2|Bacteria,1NJ94@1224|Proteobacteria,1SJCU@1236|Gammaproteobacteria,1XQQK@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15141_4 1278309.KB907099_gene2411 3.73e-111 322.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1XK4X@135619|Oceanospirillales 135619|Oceanospirillales S adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_15141_5 1278309.KB907099_gene2412 0.0 934.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XKCB@135619|Oceanospirillales 135619|Oceanospirillales H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_15141_6 1278309.KB907099_gene2413 2.7e-177 497.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XJ0A@135619|Oceanospirillales 135619|Oceanospirillales S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 k141_15141_7 1278309.KB907099_gene2414 3.2e-17 80.1 COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,1XJUQ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_22156_1 748247.AZKH_0624 2.76e-87 265.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VNV2@28216|Betaproteobacteria,2KUPV@206389|Rhodocyclales 206389|Rhodocyclales C Cysteine-rich domain - - - ko:K18928 - - - - ko00000 - - - CCG k141_22156_2 187272.Mlg_2281 2.5e-171 492.0 COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,1WXT5@135613|Chromatiales 135613|Chromatiales C LUD domain - - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom k141_8850_1 1288826.MSNKSG1_11428 1.44e-81 275.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_4770_2 626887.J057_15105 3.86e-19 85.9 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,46869@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_3979_1 443152.MDG893_02680 1.42e-144 410.0 28Q1W@1|root,2ZCK4@2|Bacteria,1RDIF@1224|Proteobacteria,1S4Y2@1236|Gammaproteobacteria,467SB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3979_2 443152.MDG893_02675 8.85e-141 403.0 COG3703@1|root,COG3703@2|Bacteria,1PJ04@1224|Proteobacteria,1S2RZ@1236|Gammaproteobacteria,469ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria P AIG2-like family - - - - - - - - - - - - AIG2_2 k141_3979_3 1288826.MSNKSG1_10283 9.49e-128 365.0 COG1309@1|root,COG1309@2|Bacteria,1N66Z@1224|Proteobacteria,1SAD4@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N k141_3979_4 1288826.MSNKSG1_10278 8.14e-163 457.0 COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,467A1@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - ko:K07124 - - - - ko00000 - - - adh_short k141_3979_5 1288826.MSNKSG1_10273 1.36e-285 783.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,464FP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_3979_6 1288826.MSNKSG1_10268 1.87e-164 461.0 COG3473@1|root,COG3473@2|Bacteria,1RC29@1224|Proteobacteria,1SJEY@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG3473 Maleate cis-trans isomerase - - - - - - - - - - - - - k141_3979_7 1288826.MSNKSG1_10263 1.54e-24 92.0 2BFPN@1|root,329I7@2|Bacteria,1QNMJ@1224|Proteobacteria,1SHZF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3096) - - - - - - - - - - - - DUF3096 k141_3979_8 1288826.MSNKSG1_10258 3.3e-235 647.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,1RMTW@1236|Gammaproteobacteria,465ER@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_3979_9 1288826.MSNKSG1_10253 0.0 1202.0 COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,1RPM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P transport of potassium into the cell kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans k141_3979_10 1288826.MSNKSG1_10248 6.46e-240 659.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,465JP@72275|Alteromonadaceae 1236|Gammaproteobacteria S NADP-dependent - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_8266_1 1121396.KB892935_gene3834 5.84e-08 61.2 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N6Y@68525|delta/epsilon subdivisions,2WJVA@28221|Deltaproteobacteria,2MI2E@213118|Desulfobacterales 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,NMT1,PAS_3,PAS_4,PAS_9,Response_reg,sCache_2 k141_6745_1 1121935.AQXX01000143_gene4160 4.79e-39 147.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XH51@135619|Oceanospirillales 135619|Oceanospirillales H COG4206 Outer membrane cobalamin receptor protein - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_17262_1 714943.Mucpa_3668 3.62e-47 170.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 k141_18673_1 266264.Rmet_5660 2.25e-41 161.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - CBS,EAL,GGDEF,PAS_9 k141_18673_3 1459636.NTE_02664 2.91e-12 73.9 COG1409@1|root,arCOG06534@1|root,arCOG07781@1|root,arCOG09729@1|root,arCOG06534@2157|Archaea,arCOG07781@2157|Archaea,arCOG09729@2157|Archaea,arCOG11020@2157|Archaea 2157|Archaea S cell adhesion involved in biofilm formation - - - - - - - - - - - - Big_1,CHB_HEX_C_1,He_PIG,PKD,Polysacc_deac_1 k141_14420_1 1279017.AQYJ01000026_gene59 2.55e-98 308.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_14420_2 1232410.KI421425_gene1544 6.6e-52 169.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales 28221|Deltaproteobacteria U Biopolymer transport protein ExbD/TolR aglS - - - - - - - - - - - ExbD k141_14420_3 1232410.KI421425_gene1545 5.66e-51 167.0 COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,43UYT@69541|Desulfuromonadales 28221|Deltaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_14420_4 396588.Tgr7_0539 6.04e-21 88.6 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1X07Q@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_5458_1 232346.JHQL01000004_gene1693 6.07e-05 51.2 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1S2IK@1236|Gammaproteobacteria,1XP33@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_22157_1 1026882.MAMP_00769 4.61e-132 414.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales 72273|Thiotrichales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_2739_4 94122.Shewana3_3102 1.13e-58 187.0 2ABHV@1|root,310Z1@2|Bacteria,1RIMU@1224|Proteobacteria,1S6DK@1236|Gammaproteobacteria,2QB7H@267890|Shewanellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2937) - - - - - - - - - - - - DUF2937 k141_2739_5 207954.MED92_13858 8.2e-105 309.0 COG4565@1|root,COG4565@2|Bacteria,1MUC7@1224|Proteobacteria,1RNEF@1236|Gammaproteobacteria,1XRCX@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulatory protein - - - - - - - - - - - - CitT,Response_reg k141_2739_6 207954.MED92_13863 2.23e-130 385.0 COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XIXX@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K02476 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_8,SPOB_a,sCache_3_2 k141_4036_2 267608.RSp1120 1.88e-77 234.0 COG2030@1|root,COG2030@2|Bacteria,1RGUP@1224|Proteobacteria,2VRWK@28216|Betaproteobacteria,1K9N6@119060|Burkholderiaceae 28216|Betaproteobacteria I N-terminal half of MaoC dehydratase maoC - - - - - - - - - - - MaoC_dehydratas k141_8999_1 1121918.ARWE01000001_gene1629 4.81e-101 306.0 COG3408@1|root,COG3408@2|Bacteria,1PGVT@1224|Proteobacteria 1224|Proteobacteria G Alkaline and neutral invertase - - - - - - - - - - - - GDE_C,Glyco_hydro_100 k141_8999_2 472759.Nhal_2558 2.88e-86 266.0 COG0561@1|root,COG3100@1|root,COG0561@2|Bacteria,COG3100@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,1WX4S@135613|Chromatiales 135613|Chromatiales S HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP,YcgL k141_7635_1 1278309.KB907099_gene2955 2.06e-100 293.0 COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria,1XJE8@135619|Oceanospirillales 135619|Oceanospirillales E Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE k141_7635_3 1278309.KB907099_gene2954 1.23e-93 277.0 COG3437@1|root,COG3437@2|Bacteria,1QW6V@1224|Proteobacteria,1T34X@1236|Gammaproteobacteria,1XRSJ@135619|Oceanospirillales 135619|Oceanospirillales KT HD domain - - - - - - - - - - - - HD k141_16685_1 1278309.KB907101_gene785 1.17e-20 88.2 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales 135619|Oceanospirillales L TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_16685_2 1278309.KB907101_gene784 5.29e-74 222.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1XKB7@135619|Oceanospirillales 135619|Oceanospirillales NU Pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_16685_3 1278309.KB907101_gene783 3.97e-13 68.2 COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria,1T1C8@1236|Gammaproteobacteria,1XRRK@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III, delta subunit, C terminal - - - - - - - - - - - - DNA_pol3_delta2,DNApol3-delta_C k141_15218_1 4081.Solyc11g021130.1.1 3.4e-14 71.6 COG0048@1|root,COG0049@1|root,KOG1750@2759|Eukaryota,KOG3291@2759|Eukaryota,37JZ5@33090|Viridiplantae,3GGCG@35493|Streptophyta,44NMZ@71274|asterids 35493|Streptophyta J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit rps7-A GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23,Ribosomal_S7 k141_5569_1 270374.MELB17_14301 8.27e-64 209.0 COG0438@1|root,COG0438@2|Bacteria,1NYTU@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k141_6816_1 1278309.KB907101_gene625 1.77e-234 658.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XITH@135619|Oceanospirillales 135619|Oceanospirillales E ABC-type oligopeptide transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_6816_2 1278309.KB907101_gene624 9.31e-235 649.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1XH8Z@135619|Oceanospirillales 135619|Oceanospirillales P With YejAEF is involved in resistance to microcin C oppB - - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_6816_3 1278309.KB907101_gene623 4.3e-234 646.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XHM2@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter permease oppC - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k141_6816_4 1278309.KB907101_gene622 0.0 896.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XH9W@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the ABC transporter superfamily oppF - - ko:K10823,ko:K13896,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00349,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_22256_3 1122132.AQYH01000015_gene2280 3.31e-20 101.0 COG5295@1|root,COG5295@2|Bacteria,1QWBE@1224|Proteobacteria 1224|Proteobacteria UW large adhesin - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collagen,ESPR,YadA_anchor,YadA_head,YadA_stalk k141_22256_6 1121440.AUMA01000011_gene2403 1.71e-05 49.7 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,43352@68525|delta/epsilon subdivisions,2X1NK@28221|Deltaproteobacteria,2MFDF@213115|Desulfovibrionales 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k141_686_1 543728.Vapar_2609 3.46e-14 76.6 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,4AAK8@80864|Comamonadaceae 28216|Betaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_9030_1 1168067.JAGP01000001_gene979 1.54e-157 469.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,461UP@72273|Thiotrichales 72273|Thiotrichales S Peptidase M16C associated - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_4047_1 1278309.KB907101_gene671 9.74e-21 89.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XH2T@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_4047_2 1278309.KB907101_gene672 3.51e-189 534.0 28MNB@1|root,2ZAXW@2|Bacteria,1R8J7@1224|Proteobacteria,1RSRT@1236|Gammaproteobacteria,1XJEH@135619|Oceanospirillales 135619|Oceanospirillales S Plasmid replication region DNA-binding N-term - - - - - - - - - - - - KfrA_N k141_4047_3 1278309.KB907101_gene673 9.56e-218 602.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XHD6@135619|Oceanospirillales 135619|Oceanospirillales K in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon cysB - - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_4047_4 1122599.AUGR01000020_gene1579 2.88e-64 207.0 COG0564@1|root,COG0564@2|Bacteria,1MX5Y@1224|Proteobacteria,1S1H1@1236|Gammaproteobacteria,1XHEC@135619|Oceanospirillales 135619|Oceanospirillales J RNA pseudouridylate synthase - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_6259_1 565653.EGBG_03026 2.66e-06 56.6 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,4B0DG@81852|Enterococcaceae 91061|Bacilli P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_2766_2 1288826.MSNKSG1_03827 9.8e-133 375.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,466XR@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG1051 ADP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX,Nudix_N_2 k141_2766_3 1288826.MSNKSG1_03832 9.63e-140 394.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1S8G8@1236|Gammaproteobacteria,46CSV@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudL - - - - - - - - - - - NUDIX k141_2766_4 1288826.MSNKSG1_03837 1.71e-67 207.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,466YX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep,Hexapep_2 k141_17400_1 105559.Nwat_3126 6.27e-127 381.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales 135613|Chromatiales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_17400_2 1123253.AUBD01000013_gene957 9.75e-07 50.1 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1X2YF@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k141_9031_1 367336.OM2255_05755 5.64e-11 64.3 COG0069@1|root,COG3369@1|root,COG0069@2|Bacteria,COG3369@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase,Rieske,zf-CDGSH k141_9031_2 768671.ThimaDRAFT_2629 2.54e-14 71.6 COG4619@1|root,COG4619@2|Bacteria,1QTWV@1224|Proteobacteria,1S627@1236|Gammaproteobacteria,1WXSI@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - - - - - - - - - - ABC_tran k141_2056_1 412597.AEPN01000006_gene1597 3.43e-79 241.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2TV8R@28211|Alphaproteobacteria,2PVZR@265|Paracoccus 28211|Alphaproteobacteria Q Methionine biosynthesis protein MetW pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_6260_1 1517416.IDAT_06615 3.5e-37 137.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,2QF0V@267893|Idiomarinaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_20074_1 1232683.ADIMK_0165 2.62e-257 712.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,463YB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_688_1 1430440.MGMSRv2_1273 1e-109 324.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,2JQ4F@204441|Rhodospirillales 204441|Rhodospirillales GK ROK family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_6830_1 1232683.ADIMK_2107 6.61e-150 442.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,1RS0H@1236|Gammaproteobacteria,46AHH@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme fcs - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding k141_16702_1 1288826.MSNKSG1_18515 1.15e-86 270.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,465MX@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase pilS - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 k141_16702_2 1288826.MSNKSG1_18520 0.0 1061.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,464PF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_16702_3 1288826.MSNKSG1_18525 9.4e-204 565.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,46691@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_16702_4 1288826.MSNKSG1_18530 6.62e-230 633.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,4643F@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_16702_5 1288826.MSNKSG1_18535 4.46e-175 488.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,466CB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the multicopper oxidase YfiH RL5 family yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_16702_6 1288826.MSNKSG1_18540 0.0 1626.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,4648S@72275|Alteromonadaceae 1236|Gammaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_16702_7 1288826.MSNKSG1_18545 1.29e-99 291.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SDH6@1236|Gammaproteobacteria,4691T@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_16702_8 1288826.MSNKSG1_18550 0.0 1140.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,464ZP@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase ilvI GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_4048_1 1348657.M622_08280 8.28e-47 165.0 2C2F5@1|root,32WND@2|Bacteria,1N9J7@1224|Proteobacteria,2W66E@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_6261_1 1229172.JQFA01000002_gene2255 1.25e-34 124.0 COG0288@1|root,COG0288@2|Bacteria,1G4T9@1117|Cyanobacteria 1117|Cyanobacteria P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_20857_2 1278309.KB907106_gene1362 4.14e-86 255.0 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,1XKIV@135619|Oceanospirillales 135619|Oceanospirillales O Peptidyl-prolyl cis-trans fkpB - 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_20857_3 1278309.KB907106_gene1363 4.69e-44 150.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1XMFR@135619|Oceanospirillales 135619|Oceanospirillales NU COG4967 Tfp pilus assembly protein PilV - - - - - - - - - - - - N_methyl k141_20857_4 1158756.AQXQ01000011_gene925 1.03e-07 58.2 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1WZ5E@135613|Chromatiales 135613|Chromatiales NU Type IV Pilus-assembly protein W - - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_2768_1 391595.RLO149_c042150 1.9e-15 74.7 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2P23I@2433|Roseobacter 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_2768_2 766499.C357_09299 2.62e-86 260.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_17401_1 1033802.SSPSH_001095 8.05e-17 78.2 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_17401_2 998674.ATTE01000001_gene2266 9.88e-80 242.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,460EK@72273|Thiotrichales 72273|Thiotrichales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_17401_3 1321778.HMPREF1982_02062 1.69e-18 82.8 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,268VH@186813|unclassified Clostridiales 186801|Clostridia I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_19500_1 1485545.JQLW01000007_gene607 2.73e-38 139.0 COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria 1224|Proteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases nnr - - ko:K01420,ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_19500_2 395493.BegalDRAFT_2930 8.27e-73 225.0 COG0235@1|root,COG0235@2|Bacteria,1QAVF@1224|Proteobacteria,1RW3I@1236|Gammaproteobacteria,4628Z@72273|Thiotrichales 72273|Thiotrichales G PFAM Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_19500_3 1158182.KB905028_gene2514 8.33e-56 206.0 COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T5TE@1236|Gammaproteobacteria,1X08C@135613|Chromatiales 135613|Chromatiales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3 k141_6262_1 1163617.SCD_n02498 1.93e-15 73.2 COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,2W3S0@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_9032_2 1121937.AUHJ01000031_gene3080 1.09e-24 93.6 COG1942@1|root,COG1942@2|Bacteria,1N7K1@1224|Proteobacteria,1SCSS@1236|Gammaproteobacteria,468GV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Tautomerase enzyme xylH - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase k141_9032_3 1278309.KB907108_gene1598 1.62e-26 101.0 COG1018@1|root,COG1018@2|Bacteria,1NA1K@1224|Proteobacteria,1SCMJ@1236|Gammaproteobacteria,1XM12@135619|Oceanospirillales 135619|Oceanospirillales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2 k141_16703_1 1266925.JHVX01000015_gene200 3.17e-28 104.0 COG2827@1|root,COG2827@2|Bacteria,1PI5S@1224|Proteobacteria,2W6RZ@28216|Betaproteobacteria,374GG@32003|Nitrosomonadales 28216|Betaproteobacteria L Endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - - k141_16703_2 1026882.MAMP_02022 7.37e-29 107.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,460RC@72273|Thiotrichales 72273|Thiotrichales O FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_2769_1 913325.N799_06325 1.05e-05 47.4 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1X3SD@135614|Xanthomonadales 135614|Xanthomonadales Q multicopper copA - - - - - - - - - - - Cu-oxidase,Cu-oxidase_3 k141_20858_1 1121904.ARBP01000032_gene2005 1.81e-121 372.0 COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 k141_18810_1 29581.BW37_01052 6.91e-15 76.6 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,473C1@75682|Oxalobacteraceae 28216|Betaproteobacteria E - Amino acid transport and metabolism asnB1 - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_18810_2 270374.MELB17_14326 1.08e-129 384.0 COG0297@1|root,COG0297@2|Bacteria,1QXFW@1224|Proteobacteria,1T3AX@1236|Gammaproteobacteria,46D4C@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0438 Glycosyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_18810_3 270374.MELB17_14306 9.75e-44 155.0 COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria,466JZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C k141_16704_1 292414.TM1040_2987 5.69e-93 281.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4NAIJ@97050|Ruegeria 28211|Alphaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 k141_6263_2 1123368.AUIS01000029_gene1282 2.84e-81 253.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,2NBXD@225057|Acidithiobacillales 225057|Acidithiobacillales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_2058_1 999611.KI421504_gene2340 1.08e-53 171.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,281CX@191028|Leisingera 28211|Alphaproteobacteria J Translation initiation factor IF-3, N-terminal domain infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_11778_1 1288826.MSNKSG1_16461 1.78e-48 157.0 COG0589@1|root,COG0589@2|Bacteria,1RG40@1224|Proteobacteria,1S7C5@1236|Gammaproteobacteria,46AX1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_11778_2 1288826.MSNKSG1_16456 0.0 1357.0 COG0697@1|root,COG2199@1|root,COG0697@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,46766@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - CHASE3,GAF_2,GGDEF k141_11778_3 1288826.MSNKSG1_16451 5.9e-197 546.0 COG1177@1|root,COG1177@2|Bacteria,1MWVC@1224|Proteobacteria,1RZW4@1236|Gammaproteobacteria,469Z9@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_11778_4 1288826.MSNKSG1_16446 8.1e-200 554.0 COG1176@1|root,COG1176@2|Bacteria,1MVFG@1224|Proteobacteria,1SYZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 k141_11778_5 1288826.MSNKSG1_16441 7.16e-256 702.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - - ABC_tran,TOBE_2 k141_11778_6 1288826.MSNKSG1_16436 1.64e-263 721.0 COG0687@1|root,COG0687@2|Bacteria,1MU12@1224|Proteobacteria,1RZEC@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Spermidine putrescine ABC transporter substrate-binding protein - - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - SBP_bac_8,TAT_signal k141_11778_7 1288826.MSNKSG1_16431 2.48e-251 689.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,4654B@72275|Alteromonadaceae 1236|Gammaproteobacteria E Required for the activity of the bacterial periplasmic transport system of putrescine potD GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0019808,GO:0019809,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSbBS512_1146.SbBS512_E2202 SBP_bac_6,SBP_bac_8 k141_11778_8 1288826.MSNKSG1_16426 2.99e-171 479.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,46461@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1177 ABC-type spermidine putrescine transport system, permease component II potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSBO_1134.SBO_1939 BPD_transp_1 k141_11778_9 1288826.MSNKSG1_16421 2.63e-184 514.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,4671A@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1176 ABC-type spermidine putrescine transport system, permease component I potB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iE2348C_1286.E2348C_1266,iECUMN_1333.ECUMN_1368,iSBO_1134.SBO_1916 BPD_transp_1 k141_11778_10 1288826.MSNKSG1_16416 5.93e-92 278.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,465ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0097159,GO:0097367,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - iB21_1397.B21_01132,iECBD_1354.ECBD_2473,iECB_1328.ECB_01124,iECD_1391.ECD_01124,iECO111_1330.ECO111_1474,iECO26_1355.ECO26_1643,iEcHS_1320.EcHS_A1246,iEcolC_1368.EcolC_2477,iSBO_1134.SBO_1915,iSSON_1240.SSON_1144,iSbBS512_1146.SbBS512_E1304,iUMNK88_1353.UMNK88_1456 ABC_tran,TOBE_2 k141_6831_1 1249627.D779_1458 3.95e-58 187.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1WXR9@135613|Chromatiales 135613|Chromatiales IQ PFAM Short-chain dehydrogenase reductase SDR fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_6831_2 2340.JV46_14780 3.95e-127 371.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1J5AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k141_17402_1 314345.SPV1_00967 6.28e-105 333.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 - - - ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,PTS_EIIA_2 k141_9833_1 1187848.AJYQ01000008_gene532 9.44e-67 218.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC2 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_4946_1 768671.ThimaDRAFT_0873 5.79e-128 380.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales 135613|Chromatiales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_14741_1 1123401.JHYQ01000007_gene566 1.48e-49 172.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,46079@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_8447_1 398580.Dshi_2373 7.23e-141 411.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_18912_2 406818.XBJ1_1862 4.64e-75 259.0 COG1196@1|root,COG1196@2|Bacteria,1R6NJ@1224|Proteobacteria,1RZRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria D ATPase involved in DNA repair - - - - - - - - - - - - - k141_15460_1 1283300.ATXB01000002_gene3036 2.87e-47 167.0 COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria,1XF0I@135618|Methylococcales 135618|Methylococcales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - HDOD k141_786_1 891968.Anamo_2010 9.54e-21 97.4 COG1459@1|root,COG1459@2|Bacteria,3T9XV@508458|Synergistetes 508458|Synergistetes U Type II secretion system - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_9834_1 1123236.KB899386_gene1913 3.45e-100 324.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,464QF@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_18913_1 187272.Mlg_0902 5.72e-35 136.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1WW11@135613|Chromatiales 135613|Chromatiales N TIGRFAM Flagellar hook-associated protein, FlgK flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_12640_1 1122137.AQXF01000001_gene3176 1.67e-42 142.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria 28211|Alphaproteobacteria G PTS IIA-like nitrogen-regulatory protein PtsN ptsN2 - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_12640_2 1122137.AQXF01000001_gene3175 2.22e-31 114.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE k141_18217_1 1278309.KB907099_gene3085 7.99e-159 452.0 COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,1XHH9@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase k141_18217_2 207954.MED92_06223 1.37e-175 494.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1XHMV@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_20336_1 187272.Mlg_0452 5.54e-168 511.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_11276_1 1269813.ATUL01000014_gene1471 1.85e-55 185.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_11276_2 2340.JV46_08600 6.31e-78 238.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1J5WR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_6354_1 1208321.D104_08430 1.21e-105 318.0 COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1 k141_8449_1 765914.ThisiDRAFT_1146 1.5e-110 333.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_21056_1 1266914.ATUK01000012_gene216 2.12e-103 312.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales 135613|Chromatiales C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_5701_1 1123392.AQWL01000002_gene1843 9.38e-20 81.6 2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_5701_2 717773.Thicy_0375 3.91e-62 204.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1T9PX@1236|Gammaproteobacteria,461QG@72273|Thiotrichales 72273|Thiotrichales S DUF218 domain - - - - - - - - - - - - DUF218 k141_5701_3 519989.ECTPHS_11010 1.86e-140 411.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales 135613|Chromatiales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_16108_1 1300345.LF41_288 1.6e-07 57.8 2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,1X5HZ@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_19596_1 1288826.MSNKSG1_15452 4.78e-215 619.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,469S2@72275|Alteromonadaceae 1236|Gammaproteobacteria C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region fdhF GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 ko:K00123,ko:K22015 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - iECBD_1354.ECBD_3953 Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_21670_1 391626.OAN307_c23830 1.03e-16 78.6 COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0685 5,10-methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_21670_2 1121479.AUBS01000001_gene3025 6.1e-94 281.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_3579_1 1149133.ppKF707_2560 1.07e-43 154.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S2ZF@1236|Gammaproteobacteria,1YEP1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_3579_2 2340.JV46_06350 0.000706 42.7 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1JA4U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_787_1 1124780.ANNU01000072_gene1068 2.22e-81 268.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k141_9835_1 177416.FTT_1677c 9.48e-91 278.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,45ZSN@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_16821_1 745411.B3C1_08923 1.12e-92 271.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1S3RV@1236|Gammaproteobacteria,1J6UN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 k141_16821_2 1288826.MSNKSG1_16601 7.33e-134 386.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,1RPSG@1236|Gammaproteobacteria,464E6@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yeiH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cons_hypoth698 k141_10550_1 500640.CIT292_08808 9.58e-21 84.0 2AHMX@1|root,317ZV@2|Bacteria,1PZIR@1224|Proteobacteria,1SU9H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2168_1 713587.THITH_06480 4.37e-147 428.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,1WY2T@135613|Chromatiales 135613|Chromatiales C PFAM Nickel-dependent hydrogenase, large subunit - - - - - - - - - - - - NiFeSe_Hases k141_12641_1 1288826.MSNKSG1_18659 1.03e-44 145.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S6K6@1236|Gammaproteobacteria,46BH3@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 k141_12641_2 1288826.MSNKSG1_18664 4.98e-57 184.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,466E0@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_18219_1 754477.Q7C_1692 5.83e-113 335.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_19597_1 545276.KB898726_gene1064 1.15e-50 173.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1WWSE@135613|Chromatiales 135613|Chromatiales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_17492_1 1237149.C900_05842 1.81e-36 141.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 k141_10551_1 1177179.A11A3_00785 6.44e-58 189.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XKHR@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial transcription activator, effector binding domain - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_4947_1 1149133.ppKF707_1072 3.7e-121 350.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1YCVM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_4947_2 1123253.AUBD01000010_gene2159 1.06e-29 111.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_6356_2 396588.Tgr7_2348 3e-32 117.0 COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,1WZ6X@135613|Chromatiales 135613|Chromatiales V Protein of unknown function (DUF559) - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - DUF559 k141_2871_1 396588.Tgr7_1968 1.23e-50 170.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1WWRA@135613|Chromatiales 135613|Chromatiales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_2871_2 1198232.CYCME_1874 9.33e-28 109.0 COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,1RR8H@1236|Gammaproteobacteria,461BP@72273|Thiotrichales 72273|Thiotrichales N Flagellar assembly protein FliH - - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_21058_1 1123517.JOMR01000001_gene1711 1.46e-64 220.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461MN@72273|Thiotrichales 72273|Thiotrichales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_18220_1 379731.PST_2550 1e-47 169.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1Z0A5@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O Cytochrome c-type biogenesis protein ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_18220_2 765912.Thimo_1354 6.69e-26 100.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1WXYI@135613|Chromatiales 135613|Chromatiales O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE k141_16822_1 1417296.U879_17210 8.09e-86 273.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_14744_1 666509.RCA23_c12000 2.33e-39 136.0 COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_14744_2 666509.RCA23_c12010 7.49e-179 502.0 COG4177@1|root,COG4177@2|Bacteria,1R35R@1224|Proteobacteria,2U27J@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_14042_1 472759.Nhal_1099 1.45e-99 306.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales 135613|Chromatiales G PFAM glycoside hydrolase, family 77 - - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_14042_2 90814.KL370891_gene1376 3.62e-23 90.1 2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,4639K@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_4260_1 314232.SKA53_06287 1.24e-97 299.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,2P8PZ@245186|Loktanella 28211|Alphaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_15461_1 1399774.JDWH01000013_gene777 5.93e-33 119.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,3X29V@547|Enterobacter 1236|Gammaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_15461_2 1268237.G114_10460 3.91e-52 168.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,1Y4CY@135624|Aeromonadales 135624|Aeromonadales N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_15461_3 686340.Metal_1782 3.67e-47 162.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1XF2A@135618|Methylococcales 135618|Methylococcales N Required for flagellar hook formation. May act as a scaffolding protein - - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_15461_4 1168065.DOK_02511 7.73e-70 228.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1J50K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_13366_2 1288826.MSNKSG1_13607 2.69e-231 638.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,4644F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_13366_3 1288826.MSNKSG1_13602 2.91e-49 156.0 COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria,468CW@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thioredoxin domain - - - - - - - - - - - - Thioredoxin_3 k141_13366_4 1288826.MSNKSG1_13597 3.2e-39 131.0 COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria,46BPN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH k141_13366_6 1288826.MSNKSG1_13587 1.17e-163 461.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,465VC@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1108 ABC-type Mn2 Zn2 transport systems, permease components znuB GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - iEC042_1314.EC042_2026,iECABU_c1320.ECABU_c21210,iECED1_1282.ECED1_2064,iECNA114_1301.ECNA114_1921,iECSF_1327.ECSF_1717,iECUMN_1333.ECUMN_2157,iEcSMS35_1347.EcSMS35_1327,iG2583_1286.G2583_2311,iSSON_1240.SSON_1282,iYL1228.KPN_02374,ic_1306.c2273 ABC-3 k141_13366_7 1288826.MSNKSG1_13582 3.03e-183 510.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,465N4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363 - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - iSFV_1184.SFV_1859,iSF_1195.SF1867,iSFxv_1172.SFxv_2092,iS_1188.S1934 ABC_tran k141_13366_8 1288826.MSNKSG1_13577 2.89e-114 327.0 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,467IR@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the Fur family zur - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR k141_13366_9 1288826.MSNKSG1_13572 2.72e-105 304.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,468MN@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0835 Chemotaxis signal transduction protein chpC - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_13366_10 1288826.MSNKSG1_13567 1.33e-253 695.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1S0CW@1236|Gammaproteobacteria,4687V@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain chpB - 3.1.1.61,3.5.1.44 ko:K03412,ko:K06597 ko02020,ko02030,map02020,map02030 M00506,M00507 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest k141_13366_11 1288826.MSNKSG1_13562 0.0 2371.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_18938_1 395493.BegalDRAFT_0572 2.2e-72 232.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,45ZZV@72273|Thiotrichales 72273|Thiotrichales P PFAM CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_8476_1 522306.CAP2UW1_2224 1.84e-115 347.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VJG4@28216|Betaproteobacteria,1KQAB@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_14765_2 1235457.C404_20630 6.71e-16 79.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria 1224|Proteobacteria M PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14 k141_20357_1 1353537.TP2_09795 1.12e-75 236.0 COG1609@1|root,COG1609@2|Bacteria,1P1Q3@1224|Proteobacteria,2TSER@28211|Alphaproteobacteria,2XM01@285107|Thioclava 28211|Alphaproteobacteria K helix_turn _helix lactose operon repressor aglR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_806_1 1288826.MSNKSG1_02073 3.27e-148 439.0 COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,1RMJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - - - - - - - - - - Peptidase_M19,Ricin_B_lectin k141_16122_1 1288826.MSNKSG1_11163 3.69e-72 227.0 COG3213@1|root,COG3213@2|Bacteria,1RE7Q@1224|Proteobacteria,1S3UC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P protein involved in response to NO - - - - - - - - - - - - NnrS k141_21680_1 349521.HCH_10038 3.83e-16 72.4 2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,1S5B2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - k141_21681_1 713586.KB900536_gene2240 2.25e-28 118.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_20358_1 930169.B5T_02962 1.18e-31 125.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XHNH@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_20358_2 870187.Thini_0654 8.63e-26 102.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,460FE@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_807_1 768066.HELO_2645 1.96e-54 190.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10567_1 686578.AFFX01000004_gene3852 1.32e-114 340.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Succinyldiaminopimelate dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_16123_1 467661.RKLH11_1797 8.87e-137 404.0 COG3962@1|root,COG3962@2|Bacteria,1MW0P@1224|Proteobacteria,2TR12@28211|Alphaproteobacteria,3ZGMV@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E Belongs to the TPP enzyme family iolD - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_14060_1 367336.OM2255_06740 6.73e-22 92.8 COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria 28211|Alphaproteobacteria G sugar phosphatases of the HAD superfamily MA20_05625 - - - - - - - - - - - Hydrolase_6,Hydrolase_like k141_14060_2 999549.KI421513_gene658 1.09e-124 363.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,2803E@191028|Leisingera 28211|Alphaproteobacteria H Riboflavin kinase ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_16839_2 1163617.SCD_n02704 1.18e-57 193.0 COG1249@1|root,COG1249@2|Bacteria,1RB5F@1224|Proteobacteria 1224|Proteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family lpdA_2 - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_932_2 1415755.JQLV01000001_gene3468 6.33e-14 67.8 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,1XJQI@135619|Oceanospirillales 135619|Oceanospirillales S nuclease - - - - - - - - - - - - NYN k141_17684_1 76869.PputGB1_5212 1.25e-46 159.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,1YVET@136845|Pseudomonas putida group 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_13491_2 1123392.AQWL01000002_gene1774 8.95e-151 446.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria 28216|Betaproteobacteria CK FMN-binding domain protein - - - - - - - - - - - - FMN_bind,Fer4_10,Fer4_5 k141_1650_1 367336.OM2255_08150 3.96e-24 105.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacF - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11,SPOR k141_14192_1 290400.Jann_2883 5.67e-25 103.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_14192_2 985054.JQEZ01000001_gene2958 6.35e-58 184.0 2CN5Z@1|root,32SGB@2|Bacteria,1N1FB@1224|Proteobacteria,2UBV1@28211|Alphaproteobacteria,4NC12@97050|Ruegeria 28211|Alphaproteobacteria S Protein of unknown function (DUF2948) MA20_21100 - - - - - - - - - - - DUF2948 k141_12112_1 1122137.AQXF01000003_gene2029 4.1e-46 165.0 COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria 1224|Proteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT_2,Pro_isomerase k141_226_1 1469613.JT55_09660 4.09e-29 111.0 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,3FEBR@34008|Rhodovulum 28211|Alphaproteobacteria S Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Erythro_esteras,Pribosyltran k141_226_2 351016.RAZWK3B_15068 2.48e-16 76.3 COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,2U8SB@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - CSD,Ribosomal_S30AE k141_2294_1 472759.Nhal_2617 5.77e-76 245.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1WWJW@135613|Chromatiales 135613|Chromatiales S protease with the C-terminal PDZ domain - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_14895_1 1288826.MSNKSG1_04946 6.14e-182 511.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,464DG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_14895_2 1288826.MSNKSG1_04951 1.32e-74 224.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,468JR@72275|Alteromonadaceae 1236|Gammaproteobacteria U preprotein translocase yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_17706_1 1122134.KB893651_gene1967 9.44e-49 171.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XI2S@135619|Oceanospirillales 135619|Oceanospirillales J Involved in the processing of the 5'end of 16S rRNA - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_19764_1 644107.SL1157_0542 9.9e-56 175.0 COG1359@1|root,COG1359@2|Bacteria,1RHSN@1224|Proteobacteria,2U9WY@28211|Alphaproteobacteria,4NC4H@97050|Ruegeria 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_11435_1 1123400.KB904758_gene2325 3.24e-37 142.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,45ZSG@72273|Thiotrichales 72273|Thiotrichales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_14196_1 160488.PP_3959 6.15e-46 164.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response Z012_08115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Voltage_CLC k141_10739_1 686340.Metal_3442 4.3e-77 240.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XEAU@135618|Methylococcales 135618|Methylococcales F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_10739_2 1026882.MAMP_02506 1.64e-122 357.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,46069@72273|Thiotrichales 72273|Thiotrichales E Belongs to the TrpC family trpC - 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PRAI k141_7232_1 381666.PHG091 1.93e-210 591.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,1K6S4@119060|Burkholderiaceae 28216|Betaproteobacteria C Nickel-dependent hydrogenase hoxH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 ko:K00436 - - R00700 - ko00000,ko01000 - - - NiFeSe_Hases k141_13495_1 1288826.MSNKSG1_07618 0.0 1276.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria,465XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_13495_2 1288826.MSNKSG1_07623 1.37e-157 443.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,465VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_13495_3 1288826.MSNKSG1_07628 7.57e-67 203.0 COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria,4693I@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1734 DnaK suppressor protein - - - - - - - - - - - - zf-dskA_traR k141_13495_4 1288826.MSNKSG1_07633 0.0 1079.0 COG2905@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465FS@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CBS,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_13495_5 443152.MDG893_18512 9.6e-138 412.0 COG0840@1|root,COG0840@2|Bacteria,1MWU2@1224|Proteobacteria,1RR1Q@1236|Gammaproteobacteria,4661J@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_16991_1 425104.Ssed_2176 5.22e-22 92.8 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,2QBZN@267890|Shewanellaceae 1236|Gammaproteobacteria C Transketolase, pyrimidine binding domain pdhB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_16991_2 991905.SL003B_1093 4.46e-16 84.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,4BPRH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_21885_1 1278309.KB907108_gene1555 8.79e-248 681.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XHH8@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k141_21885_2 1278309.KB907108_gene1554 4.11e-71 214.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1XKES@135619|Oceanospirillales 135619|Oceanospirillales U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_21885_3 1278309.KB907108_gene1553 0.0 1031.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XHAC@135619|Oceanospirillales 135619|Oceanospirillales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_21885_4 1278309.KB907108_gene1552 9.17e-176 494.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1XIA9@135619|Oceanospirillales 135619|Oceanospirillales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_16252_1 1288826.MSNKSG1_17406 4.06e-182 508.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae 1236|Gammaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_3756_1 1121937.AUHJ01000005_gene2298 1.55e-50 186.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_1676_1 1218173.BALCAV_0213495 6.75e-05 50.8 COG3563@1|root,COG3563@2|Bacteria,1UAFI@1239|Firmicutes,4IKTX@91061|Bacilli,1ZHJJ@1386|Bacillus 91061|Bacilli M Capsule polysaccharide biosynthesis protein - - - - - - - - - - - - Capsule_synth k141_3063_1 1278309.KB907099_gene3002 1.07e-119 350.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1XHEQ@135619|Oceanospirillales 135619|Oceanospirillales C NADH flavin oxidoreductase - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_3063_2 506534.Rhein_0864 1.1e-59 184.0 COG0640@1|root,COG0640@2|Bacteria,1N0DR@1224|Proteobacteria,1SAAE@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional - - - - - - - - - - - - HTH_20 k141_3063_3 1278309.KB907099_gene3000 3.14e-130 373.0 COG2102@1|root,COG2102@2|Bacteria,1RIT6@1224|Proteobacteria,1S9YD@1236|Gammaproteobacteria,1XQ8F@135619|Oceanospirillales 135619|Oceanospirillales S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 k141_3063_4 1265503.KB905161_gene2992 4.82e-57 203.0 COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,1S0C5@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,Hemerythrin,PAS_3 k141_3063_5 1298593.TOL_1174 7.62e-59 190.0 COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,1RSHR@1236|Gammaproteobacteria,1XK57@135619|Oceanospirillales 135619|Oceanospirillales D Involved in chromosome partitioning - - - - - - - - - - - - - k141_21222_1 367336.OM2255_05950 1.25e-108 332.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2TRND@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA1 - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_252_2 187272.Mlg_2835 8.89e-23 95.9 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WWR6@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator, LysR - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_9284_1 765914.ThisiDRAFT_1186 1.16e-39 144.0 COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1X2ER@135613|Chromatiales 135613|Chromatiales M Bacterial lipid A biosynthesis acyltransferase - - 2.3.1.243 ko:K02560 ko00540,ko01100,map00540,map01100 M00060 R05075 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_5123_1 1415778.JQMM01000001_gene1342 6.14e-06 49.7 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4Q2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_15600_2 322710.Avin_09930 8.53e-94 284.0 COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,1S1NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the EutC family eutC GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0008851,GO:0009350,GO:0016829,GO:0016840,GO:0016841,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 ko:K03736 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutC k141_15600_3 1552758.NC00_19800 8.58e-138 403.0 COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria,1X5RG@135614|Xanthomonadales 135614|Xanthomonadales E Ethanolamine ammonia-lyase eutA - 4.3.1.7 ko:K03735 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001,ko01000 - - - EutB k141_952_1 400668.Mmwyl1_2475 4.82e-193 550.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XNNR@135619|Oceanospirillales 135619|Oceanospirillales U Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_21886_1 870187.Thini_2194 1.51e-62 198.0 COG2128@1|root,COG2128@2|Bacteria,1RHU7@1224|Proteobacteria,1S8PB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k141_12811_1 1122604.JONR01000006_gene2524 1.3e-93 283.0 COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria,1X47H@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2167) - - - - - - - - - - - - DUF2167 k141_20526_1 1120953.AUBH01000004_gene2964 3.05e-65 202.0 COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,1SZJ5@1236|Gammaproteobacteria,46B6Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C Globin - - - - - - - - - - - - Globin k141_6483_1 246200.SPO3771 8.92e-41 142.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,4NB8R@97050|Ruegeria 28211|Alphaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP GO:0008150,GO:0042221,GO:0046677,GO:0050896 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_6483_2 367336.OM2255_09561 1.14e-147 426.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM 3-beta hydroxysteroid dehydrogenase MA20_24380 - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind k141_19116_1 1049564.TevJSym_ac01960 1.16e-61 194.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_11436_1 765914.ThisiDRAFT_1150 5.11e-72 231.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_3064_1 631362.Thi970DRAFT_01620 8.83e-100 292.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales 135613|Chromatiales O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA k141_13496_1 1123360.thalar_01532 1.83e-76 240.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,Transket_pyr,Transketolase_C k141_13496_2 1238182.C882_0948 1.73e-48 169.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,2JPJK@204441|Rhodospirillales 204441|Rhodospirillales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_7963_1 1390370.O203_20665 2.14e-13 66.6 COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1YGP6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Belongs to the UPF0235 family yggU - - ko:K09131 - - - - ko00000 - - - DUF167 k141_7963_2 1049564.TevJSym_am00180 4.98e-57 185.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1J6HX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_7963_3 754477.Q7C_1630 1.58e-73 230.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,45ZU9@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_7233_1 519989.ECTPHS_02169 2.54e-145 418.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_2316_2 1046627.BZARG_2909 2.21e-07 52.8 COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia 976|Bacteroidetes P rhodanese-related sulfurtransferase - - - - - - - - - - - - Rhodanese,Thioredoxin k141_4484_1 572477.Alvin_0391 1.96e-95 290.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1WVX6@135613|Chromatiales 135613|Chromatiales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_4484_2 257313.BP2385 6.16e-20 84.3 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,3T4D6@506|Alcaligenaceae 28216|Betaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_4484_3 1188252.AJYK01000021_gene1474 8.01e-70 220.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1XTAS@135623|Vibrionales 135623|Vibrionales I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_12812_1 1303518.CCALI_01052 1.47e-30 122.0 COG0745@1|root,COG2199@1|root,COG3829@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria 2|Bacteria T transcription factor binding cph2_1 - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - 5TM-5TMR_LYT,GGDEF,PAS,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg k141_3758_1 400682.PAC_15711160 1.37e-31 121.0 COG1131@1|root,KOG0059@2759|Eukaryota,3AAD7@33154|Opisthokonta,3C2VZ@33208|Metazoa 33208|Metazoa I ABC transporter - - - - - - - - - - - - ABC_tran k141_18391_1 1249627.D779_4120 6.84e-63 204.0 COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,1WZ29@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF599 - - - - - - - - - - - - DUF599 k141_12128_1 1288826.MSNKSG1_16001 1.46e-104 302.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S0DD@1236|Gammaproteobacteria,467TF@72275|Alteromonadaceae 1236|Gammaproteobacteria I dehydratase nodN - - - - - - - - - - - MaoC_dehydratas k141_12128_2 1288826.MSNKSG1_16006 2.32e-182 507.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,466NS@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - - - - - - - - - - Aldolase_II k141_12128_3 1288826.MSNKSG1_16011 3.87e-204 569.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1RPNI@1236|Gammaproteobacteria,46AES@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_15602_1 113395.AXAI01000003_gene5608 4.58e-74 241.0 COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1MXAH@1224|Proteobacteria,2U2YR@28211|Alphaproteobacteria,3JYXY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria DL AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - AAA_15,AAA_21,DUF2813 k141_14197_1 1121948.AUAC01000002_gene1254 8.36e-155 446.0 COG1292@1|root,COG1292@2|Bacteria,1MWXP@1224|Proteobacteria,2U0PE@28211|Alphaproteobacteria,43Z2N@69657|Hyphomonadaceae 28211|Alphaproteobacteria M BCCT, betaine/carnitine/choline family transporter - - - - - - - - - - - - BCCT k141_10740_1 1288826.MSNKSG1_02223 2.17e-151 432.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPGB@1236|Gammaproteobacteria,464X4@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases hcaD - 1.3.8.7,1.3.8.8 ko:K00249,ko:K00255 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_10740_2 1288826.MSNKSG1_02218 1.79e-139 397.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,465Z6@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short,adh_short_C2 k141_16255_1 765912.Thimo_2452 1.19e-79 265.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales 135613|Chromatiales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_5840_1 391595.RLO149_c004110 5.41e-88 288.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2P1XW@2433|Roseobacter 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_5840_4 573370.DMR_29390 1.98e-13 66.2 2AIAJ@1|root,318RF@2|Bacteria,1Q0TX@1224|Proteobacteria,436X4@68525|delta/epsilon subdivisions,2X9MZ@28221|Deltaproteobacteria,2MFAM@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_5840_5 1051676.G0YPX5_9CAUD 1.43e-23 95.5 4QHC8@10239|Viruses,4QV8S@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKFD@10662|Myoviridae 10662|Myoviridae S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k141_5840_10 913865.DOT_2883 5.15e-05 52.8 COG5301@1|root,COG5301@2|Bacteria,1UW80@1239|Firmicutes,24WF3@186801|Clostridia,266CV@186807|Peptococcaceae 186801|Clostridia G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - k141_9423_1 1123228.AUIH01000007_gene2501 2.39e-47 159.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales 135619|Oceanospirillales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_9423_2 1304275.C41B8_15847 9.73e-20 82.8 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria 1236|Gammaproteobacteria H protein conserved in bacteria - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - DUF971 k141_2496_1 472759.Nhal_0349 2.68e-77 243.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1WXB6@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_2496_2 29486.NJ56_11890 3.31e-24 94.0 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,41G8K@629|Yersinia 1236|Gammaproteobacteria K Belongs to the BolA IbaG family yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - - - - - - - - - - BolA k141_2496_3 697282.Mettu_0180 3.61e-07 49.7 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XFQI@135618|Methylococcales 135618|Methylococcales S STAS domain - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 k141_13677_1 1288826.MSNKSG1_18070 4.37e-155 439.0 COG3025@1|root,COG3025@2|Bacteria,1MY43@1224|Proteobacteria,1RMP4@1236|Gammaproteobacteria,463Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Adenylate cyclase ygiF - 3.6.1.25 ko:K18446 - - - - ko00000,ko01000 - - - CHAD,CYTH k141_13677_2 1288826.MSNKSG1_18075 0.0 1545.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_12303_1 1454004.AW11_02753 8.72e-66 213.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,1KR7J@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria U ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_12303_2 1454004.AW11_02752 4.45e-12 66.2 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria,1KQU1@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990,ko:K13926 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3,ABC_tran k141_6643_1 1123368.AUIS01000001_gene2006 8.28e-82 256.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,2NC48@225057|Acidithiobacillales 225057|Acidithiobacillales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_6643_2 1382304.JNIL01000001_gene1874 6.39e-67 212.0 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,4HDFS@91061|Bacilli 91061|Bacilli L Site-specific DNA-methyltransferase (Adenine-specific) dpnM - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k141_15043_1 95619.PM1_0215935 1.35e-156 447.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_15043_2 998674.ATTE01000001_gene2818 4.44e-35 129.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,45ZQI@72273|Thiotrichales 72273|Thiotrichales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_11571_1 225937.HP15_704 2.69e-117 346.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,46586@72275|Alteromonadaceae 1236|Gammaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_18514_1 395493.BegalDRAFT_1237 3.09e-21 87.8 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,4614W@72273|Thiotrichales 72273|Thiotrichales S PFAM Smr - - - - - - - - - - - - Smr k141_18514_2 1391646.AVSU01000019_gene1320 0.000626 47.8 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25SPV@186804|Peptostreptococcaceae 186801|Clostridia NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_10151_1 1123368.AUIS01000019_gene1218 4.43e-40 140.0 COG1416@1|root,COG1416@2|Bacteria,1N5DH@1224|Proteobacteria,1SF5J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_10907_1 1122599.AUGR01000013_gene708 7.68e-143 411.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1XHSC@135619|Oceanospirillales 135619|Oceanospirillales P Iron deficiency-induced protein A - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 k141_10907_2 1278309.KB907102_gene88 1.16e-21 94.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1XI4T@135619|Oceanospirillales 135619|Oceanospirillales P iron ABC transporter permease - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_17872_1 1288826.MSNKSG1_10203 2.89e-48 159.0 COG0179@1|root,COG0179@2|Bacteria,1R51B@1224|Proteobacteria,1RQI9@1236|Gammaproteobacteria,469ZF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpaG1 - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_17872_2 1288826.MSNKSG1_10208 6.07e-107 313.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,469W8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpaG - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_5214,iEcHS_1320.EcHS_A4584 FAA_hydrolase k141_19905_2 1500301.JQMF01000006_gene1766 2.02e-44 149.0 2E0FP@1|root,300A6@2|Bacteria,1PQHQ@1224|Proteobacteria,2V2WQ@28211|Alphaproteobacteria,4BJS5@82115|Rhizobiaceae 28211|Alphaproteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k141_4627_1 118161.KB235922_gene2196 4.89e-05 50.4 COG2831@1|root,COG2831@2|Bacteria,1G03B@1117|Cyanobacteria,3VMJ7@52604|Pleurocapsales 1117|Cyanobacteria U Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - - - - - - - - - - POTRA_2,ShlB k141_18515_1 1046724.KB889952_gene2063 4.42e-97 311.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria,46AHK@72275|Alteromonadaceae 1236|Gammaproteobacteria L Putative phage integrase - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_integrase k141_12304_1 857087.Metme_4082 3.92e-107 319.0 COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1XH17@135618|Methylococcales 135618|Methylococcales J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB - - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_7385_1 1123514.KB905899_gene1276 5.12e-94 291.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - - - - - - - - - - - G6PD_C,G6PD_N k141_20650_1 1288826.MSNKSG1_11833 2.64e-74 229.0 2EBDF@1|root,335E4@2|Bacteria,1NH7B@1224|Proteobacteria,1SHGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20650_2 1288826.MSNKSG1_11838 0.0 1095.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4653D@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the TPP enzyme family budB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_20650_3 1288826.MSNKSG1_11843 1.46e-127 380.0 2C593@1|root,2Z84R@2|Bacteria,1Q8PC@1224|Proteobacteria,1RP26@1236|Gammaproteobacteria,46680@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15044_1 367336.OM2255_09176 1.07e-97 292.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_22029_1 396588.Tgr7_0872 1.49e-205 582.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WX93@135613|Chromatiales 135613|Chromatiales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_22029_2 481448.Minf_2003 5.05e-56 192.0 COG0837@1|root,COG0837@2|Bacteria,46WVA@74201|Verrucomicrobia,37H2E@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia F Glucokinase glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_17120_2 1278309.KB907100_gene2078 5.53e-284 778.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XHK6@135619|Oceanospirillales 135619|Oceanospirillales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_17120_3 1278309.KB907100_gene2077 1.5e-122 354.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XHA1@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_15785_1 1278309.KB907100_gene2066 4.87e-154 447.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1XHI6@135619|Oceanospirillales 135619|Oceanospirillales IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_15785_2 1278309.KB907100_gene2065 6.56e-151 439.0 COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,1RZ3B@1236|Gammaproteobacteria,1XIZI@135619|Oceanospirillales 135619|Oceanospirillales T COG2202 FOG PAS PAC domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9 k141_5966_1 1278309.KB907106_gene1283 1.66e-129 379.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales 135619|Oceanospirillales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_5966_2 717774.Marme_0583 2.87e-54 204.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQ69@1236|Gammaproteobacteria,1XJ95@135619|Oceanospirillales 135619|Oceanospirillales NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_4646_1 1278309.KB907100_gene2317 3.98e-127 374.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XH9N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase k141_13023_1 1168067.JAGP01000001_gene1061 1.95e-68 214.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,460TE@72273|Thiotrichales 72273|Thiotrichales D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA k141_19308_1 1049564.TevJSym_an00370 1.01e-219 610.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1J4R3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG0191 Fructose tagatose bisphosphate aldolase fba - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k141_15819_1 1163409.UUA_14134 6.5e-85 265.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria,1X3AG@135614|Xanthomonadales 135614|Xanthomonadales E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k141_1837_1 1236689.MMALV_05400 0.000114 50.4 COG1134@1|root,COG1479@1|root,arCOG00210@2157|Archaea,arCOG05223@2157|Archaea,2XVSX@28890|Euryarchaeota 28890|Euryarchaeota E ABC transporter - - - ko:K01990,ko:K09691 ko02010,map02010 M00250,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 - - ABC_tran,Wzt_C k141_11585_1 1168067.JAGP01000001_gene2157 2.38e-57 194.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T2WX@1236|Gammaproteobacteria,462NY@72273|Thiotrichales 72273|Thiotrichales T Diguanylate cyclase - - - - - - - - - - - - GAF,GGDEF,PAS_2,PHY k141_20665_1 765910.MARPU_15335 2.62e-44 164.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2,sCache_2 k141_1166_1 1042375.AFPL01000013_gene2469 9.38e-255 704.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,46532@72275|Alteromonadaceae 1236|Gammaproteobacteria F Amidohydrolase family hydA - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 k141_5988_1 1278309.KB907099_gene2601 5.76e-181 515.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XIJJ@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_19309_1 1002340.AFCF01000066_gene391 2.62e-95 293.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,34FBY@302485|Phaeobacter 28211|Alphaproteobacteria C Cytochrome C and Quinol oxidase polypeptide I ccoN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_13708_1 754476.Q7A_2395 3.64e-31 120.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,4610C@72273|Thiotrichales 72273|Thiotrichales N Belongs to the bacterial flagellin family - - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_13708_2 1121035.AUCH01000020_gene2666 6.26e-12 66.2 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,2KVUK@206389|Rhodocyclales 206389|Rhodocyclales N Belongs to the flagella basal body rod proteins family flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_460_2 1357279.N018_07230 3.1e-38 138.0 COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1Z4MS@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M NAD(P)H-binding wbpV - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_17147_1 1123401.JHYQ01000018_gene2399 2.99e-55 194.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,45ZXM@72273|Thiotrichales 72273|Thiotrichales C 2-oxoglutarate dehydrogenase, E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_3896_1 1469613.JT55_16665 8.9e-86 263.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - - - - - - - - - - ABC_tran,oligo_HPY k141_18539_1 338963.Pcar_2558 9.73e-86 289.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales 28221|Deltaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg k141_18539_2 586413.CCDL010000004_gene3330 5.74e-29 120.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,23K5P@182709|Oceanobacillus 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ghrA - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_18539_3 1278309.KB907101_gene414 8.63e-105 309.0 COG4807@1|root,COG4807@2|Bacteria,1RD33@1224|Proteobacteria,1S3ZU@1236|Gammaproteobacteria,1XJUE@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1456) - - - - - - - - - - - - DUF1456 k141_13024_1 1123368.AUIS01000036_gene90 2.04e-51 186.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - CHASE,CHASE8,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_16438_1 391615.ABSJ01000042_gene2274 7.11e-54 184.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_16438_2 748280.NH8B_3471 5.4e-48 159.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,2KR8G@206351|Neisseriales 206351|Neisseriales S Psort location Cytoplasmic, score 8.96 - - - ko:K09117 - - - - ko00000 - - - YqeY k141_7411_1 713586.KB900536_gene2551 2.12e-46 167.0 COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,1WXQ5@135613|Chromatiales 135613|Chromatiales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_21390_1 1121403.AUCV01000038_gene4227 1.04e-209 591.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,42NDR@68525|delta/epsilon subdivisions,2WJQ4@28221|Deltaproteobacteria 1224|Proteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_4648_1 935840.JAEQ01000019_gene2093 5.46e-25 102.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,43J36@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Transcriptional regulator iclR - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_4648_2 1461694.ATO9_07135 6.99e-26 106.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,2PCIS@252301|Oceanicola 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 k141_12332_1 243090.RB3271 5.16e-49 169.0 COG0515@1|root,COG0515@2|Bacteria,2IX48@203682|Planctomycetes 203682|Planctomycetes KLT COG0515 Serine threonine protein - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_20666_1 357804.Ping_2327 3.11e-40 147.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,2QJ72@267894|Psychromonadaceae 1236|Gammaproteobacteria P Chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_8768_1 204773.HEAR1595 2.41e-169 502.0 COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,2VIUK@28216|Betaproteobacteria,475BD@75682|Oxalobacteraceae 28216|Betaproteobacteria C Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrom_C,Cytochrome_CBB3,FTR1 k141_13709_1 391624.OIHEL45_06405 8.12e-58 187.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TRAP transporter solute receptor TAXI family imp - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_1839_1 1232683.ADIMK_2003 5.25e-43 144.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,467A9@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0314 Molybdopterin converting factor, large subunit moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1305,iEC042_1314.EC042_0869,iEC55989_1330.EC55989_0828,iECABU_c1320.ECABU_c08270,iECED1_1282.ECED1_0750,iECIAI1_1343.ECIAI1_0820,iECIAI39_1322.ECIAI39_0761,iECNA114_1301.ECNA114_0717,iECO103_1326.ECO103_0820,iECO111_1330.ECO111_0846,iECO26_1355.ECO26_0911,iECOK1_1307.ECOK1_0787,iECP_1309.ECP_0799,iECS88_1305.ECS88_0802,iECSE_1348.ECSE_0839,iECSF_1327.ECSF_0711,iECW_1372.ECW_m0841,iEKO11_1354.EKO11_3101,iEcE24377_1341.EcE24377A_0848,iG2583_1286.G2583_1013,iLF82_1304.LF82_1369,iNRG857_1313.NRG857_03500,iSSON_1240.SSON_0764,iUMN146_1321.UM146_13720,iUTI89_1310.UTI89_C0785,iWFL_1372.ECW_m0841,ic_1306.c0867 MoaE k141_14331_1 1454004.AW11_02413 1.11e-68 220.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria 28216|Betaproteobacteria T Response regulator receiver cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_14331_2 926551.KB900707_gene603 4.77e-07 55.8 COG0526@1|root,COG0526@2|Bacteria,4P116@976|Bacteroidetes 976|Bacteroidetes CO Glutathione peroxidase - - - - - - - - - - - - AhpC-TSA k141_15820_1 1042375.AFPL01000013_gene2464 1.49e-162 466.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,4658N@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_19310_1 1123279.ATUS01000001_gene2323 1.96e-08 55.5 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1J4V0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N k141_19310_2 1056820.KB900700_gene1163 1.57e-32 126.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,2PMQ1@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria JK 16S rRNA methyltransferase RsmB/F sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_16439_1 1449350.OCH239_05385 1.21e-61 213.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,4KKS0@93682|Roseivivax 28211|Alphaproteobacteria L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_7412_1 1112217.PPL19_10387 6.1e-58 189.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria 1236|Gammaproteobacteria N flagellar basal body flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_6662_1 270374.MELB17_04537 1.31e-11 65.5 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,46465@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM k141_6662_2 927677.ALVU02000001_gene925 4.87e-69 237.0 COG3322@1|root,COG3852@1|root,COG5001@1|root,COG3322@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS_3,PAS_4,PAS_9 k141_17149_1 1056820.KB900633_gene2023 0.00041 42.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,2PNW6@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_17149_2 349521.HCH_02633 4.4e-19 85.1 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1XMGD@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_20765_1 1288826.MSNKSG1_17291 2e-136 393.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,465EC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_20765_2 1288826.MSNKSG1_17296 0.0 1249.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,465QM@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPases (dynamin-related) - - - - - - - - - - - - Dynamin_N k141_20765_3 1288826.MSNKSG1_17301 7.82e-125 357.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,467FD@72275|Alteromonadaceae 1236|Gammaproteobacteria S integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_20765_4 1288826.MSNKSG1_17306 1.49e-179 501.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,466CZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_20765_5 1288826.MSNKSG1_17311 2.41e-140 398.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,466EB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_20765_6 1288826.MSNKSG1_17316 6.75e-244 670.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,464R4@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT pilT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_15963_1 1288826.MSNKSG1_12767 2.99e-216 613.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,464V1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iJN746.PP_5217 PP_kinase,PP_kinase_C,PP_kinase_N k141_15963_2 1288826.MSNKSG1_12772 1.19e-233 644.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,464JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_19425_1 1112217.PPL19_02495 0.000314 42.7 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin 4 family protein ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_19425_2 1453501.JELR01000001_gene2296 2.09e-90 278.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_21535_1 1288826.MSNKSG1_16896 4.97e-236 649.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,465TW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily dppF - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_21535_2 1288826.MSNKSG1_16891 8.4e-133 382.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,464HS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component - - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_15166_1 765912.Thimo_2955 8.38e-32 115.0 COG2193@1|root,COG2193@2|Bacteria,1PE4V@1224|Proteobacteria,1SAG5@1236|Gammaproteobacteria,1WZ24@135613|Chromatiales 135613|Chromatiales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_2664_1 1278309.KB907104_gene968 9.69e-86 259.0 2DUFW@1|root,33QG9@2|Bacteria,1R2X8@1224|Proteobacteria,1T5ZH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_22206_1 1288826.MSNKSG1_07108 1.15e-96 290.0 COG3317@1|root,COG3317@2|Bacteria 2|Bacteria M Gram-negative-bacterium-type cell outer membrane assembly bamC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045229,GO:0061024,GO:0071709,GO:0071840,GO:0071944,GO:0098552,GO:0098796,GO:1990063 - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_22206_2 1288826.MSNKSG1_07113 4.56e-209 578.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,464AC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812 DHDPS k141_22206_3 1288826.MSNKSG1_07118 2.41e-109 314.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,46AS0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_22206_4 1288826.MSNKSG1_07123 7.24e-242 666.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,465AI@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_22206_5 1288826.MSNKSG1_07128 1.68e-36 123.0 COG0425@1|root,COG0425@2|Bacteria 2|Bacteria O sulfur carrier activity - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_22206_6 1288826.MSNKSG1_07133 1.1e-129 380.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,465XU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k141_16611_1 1288826.MSNKSG1_05963 0.0 1050.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,464XN@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_16611_2 1288826.MSNKSG1_05968 4.21e-285 778.0 COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,465A9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_16611_3 1288826.MSNKSG1_05973 2.8e-193 550.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0514 Superfamily II DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_3413_1 1278309.KB907110_gene3219 4.83e-72 219.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1XM5C@135619|Oceanospirillales 135619|Oceanospirillales T Positive regulator of algM - - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_3413_2 1523503.JPMY01000012_gene3298 0.00051 43.5 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_8325_1 748658.KB907312_gene1306 1.64e-07 52.8 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales 135613|Chromatiales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_8325_2 1026882.MAMP_00914 4.33e-201 570.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,46174@72273|Thiotrichales 72273|Thiotrichales C NADH dehydrogenase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_15964_1 1122134.KB893650_gene636 3.49e-11 64.3 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XM7Q@135619|Oceanospirillales 135619|Oceanospirillales S SURF1-like protein - - - - - - - - - - - - SURF1 k141_15964_2 323261.Noc_3043 9.46e-12 62.0 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SX44@1236|Gammaproteobacteria,1X1XD@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 k141_9587_1 1278309.KB907101_gene353 9.43e-235 652.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,1XIET@135619|Oceanospirillales 135619|Oceanospirillales G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM k141_9587_2 1278309.KB907101_gene354 8.96e-70 213.0 COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,1SBIE@1236|Gammaproteobacteria,1XMWJ@135619|Oceanospirillales 135619|Oceanospirillales P Hemerythrin - - - ko:K07216 - - - - ko00000 - - - Hemerythrin k141_9587_3 1278309.KB907103_gene1212 5.75e-10 59.7 COG2271@1|root,COG2271@2|Bacteria,1QX38@1224|Proteobacteria,1T35H@1236|Gammaproteobacteria,1XKGR@135619|Oceanospirillales 135619|Oceanospirillales G Uncharacterised MFS-type transporter YbfB - - - - - - - - - - - - MFS_1 k141_8889_1 1535422.ND16A_1844 1.19e-189 539.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,2Q65D@267889|Colwelliaceae 1236|Gammaproteobacteria E Aminotransferase class-V sufS - 2.8.1.7,4.4.1.16 ko:K01766,ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_19426_1 1122137.AQXF01000002_gene142 3.51e-96 303.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_6134_1 1392498.JQLH01000001_gene2493 7.52e-74 235.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1IGCV@117743|Flavobacteriia,2PI59@252356|Maribacter 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC k141_22207_1 246200.SPO1376 6.56e-66 222.0 COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,2TR9F@28211|Alphaproteobacteria,4NADV@97050|Ruegeria 28211|Alphaproteobacteria M Glycosyl transferase, group 2 family - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N k141_13865_1 717774.Marme_2434 1.82e-169 479.0 COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,1RPSI@1236|Gammaproteobacteria,1XNBQ@135619|Oceanospirillales 135619|Oceanospirillales C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase k141_13865_2 717774.Marme_2433 9.29e-75 238.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XN63@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18730_2 59538.XP_005974317.1 6.69e-22 94.7 COG1011@1|root,COG2227@1|root,KOG1270@2759|Eukaryota,KOG3085@2759|Eukaryota,39T8B@33154|Opisthokonta,3BXGZ@33208|Metazoa,3DD9U@33213|Bilateria,48JQX@7711|Chordata,49GQV@7742|Vertebrata,3JJKD@40674|Mammalia,4JCDA@91561|Cetartiodactyla 33154|Opisthokonta H Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial-like COQ3 GO:0003674,GO:0003824,GO:0004395,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0010420,GO:0016020,GO:0016740,GO:0016741,GO:0019866,GO:0019898,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0042180,GO:0042181,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0061542,GO:0061543,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.114,2.1.1.222,2.1.1.64 ko:K00568,ko:K00591 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117,M00128 R02175,R04711,R04988,R05614,R07235,R08769,R08771,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 k141_4007_1 1469245.JFBG01000040_gene1716 1.41e-86 279.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_2665_1 1278309.KB907103_gene1164 9.77e-125 373.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XHDQ@135619|Oceanospirillales 135619|Oceanospirillales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_12512_1 637905.SVI_4255 8.64e-25 96.3 COG1359@1|root,COG1359@2|Bacteria,1NG3M@1224|Proteobacteria,1T7FK@1236|Gammaproteobacteria,2QD0K@267890|Shewanellaceae 1236|Gammaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_12512_2 1232683.ADIMK_3904 2.25e-30 109.0 COG0454@1|root,COG0454@2|Bacteria,1RJDV@1224|Proteobacteria,1S6V1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10 k141_21536_1 351348.Maqu_0652 2.86e-12 65.5 COG4643@1|root,COG4643@2|Bacteria,1MVGY@1224|Proteobacteria,1S7S5@1236|Gammaproteobacteria,46AWU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Toprim domain - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Toprim_3,Toprim_4 k141_21536_2 1046724.KB889869_gene2525 6.21e-107 324.0 COG4983@1|root,COG4983@2|Bacteria,1N636@1224|Proteobacteria,1RZVN@1236|Gammaproteobacteria,46ACV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k141_1330_2 345073.VC395_0422 1.26e-129 379.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XUYB@135623|Vibrionales 135623|Vibrionales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_18085_1 351348.Maqu_0228 0.0 1077.0 COG0457@1|root,COG0457@2|Bacteria,1QV4P@1224|Proteobacteria,1SJ0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K SIR2-like domain - - - - - - - - - - - - SIR2_2 k141_15965_1 1123501.KB902288_gene1823 1.5e-66 212.0 COG5387@1|root,COG5387@2|Bacteria,1Q3B5@1224|Proteobacteria,2TVK1@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - - - - - - - - - - ATP12 k141_3415_1 1449076.JOOE01000002_gene744 1.74e-81 255.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,2K1VS@204457|Sphingomonadales 204457|Sphingomonadales E Aminomethyltransferase folate-binding domain - - 2.1.1.341 ko:K15066 ko00627,ko01120,map00627,map01120 - R09271,R10136 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C k141_10358_1 351348.Maqu_2388 0.0 1294.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_10358_2 1288826.MSNKSG1_00561 0.0 1208.0 COG3209@1|root,COG3209@2|Bacteria,1QXGF@1224|Proteobacteria,1SG59@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - k141_10358_3 1288826.MSNKSG1_00556 9.05e-312 852.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_10358_4 1288826.MSNKSG1_00551 1.1e-70 215.0 COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C epsilon subunit - - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_10358_5 1288826.MSNKSG1_00546 2.22e-49 157.0 2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_16613_1 1232683.ADIMK_1056 5.4e-94 288.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,4647E@72275|Alteromonadaceae 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_9588_1 1523503.JPMY01000037_gene1748 1.47e-50 185.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_11718_2 765911.Thivi_2355 1.06e-36 150.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2,sCache_2 k141_4805_1 1384054.N790_09465 6.15e-60 194.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1X3H9@135614|Xanthomonadales 135614|Xanthomonadales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_4805_2 472759.Nhal_3735 6.24e-95 285.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1WWJ2@135613|Chromatiales 135613|Chromatiales O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans k141_4805_3 1424334.W822_22150 1.2e-08 56.2 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,3T2JI@506|Alcaligenaceae 28216|Betaproteobacteria S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_13866_1 243159.AFE_0854 3.12e-06 48.5 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,2NCHV@225057|Acidithiobacillales 225057|Acidithiobacillales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_18731_1 441620.Mpop_4763 1.07e-37 129.0 COG3636@1|root,COG3636@2|Bacteria,1N0RK@1224|Proteobacteria,2UDN3@28211|Alphaproteobacteria,1JVF2@119045|Methylobacteriaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - k141_15966_1 985054.JQEZ01000001_gene2898 6.42e-38 130.0 COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2TVBW@28211|Alphaproteobacteria,4NCCZ@97050|Ruegeria 28211|Alphaproteobacteria O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly ureE - - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N k141_15966_2 316058.RPB_1868 2.97e-32 120.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2TRVW@28211|Alphaproteobacteria,3JSYT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_8891_1 236097.ADG881_359 2.05e-72 227.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XI2H@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_17305_1 1278309.KB907101_gene457 9.46e-128 389.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTVB@1224|Proteobacteria,1RYDJ@1236|Gammaproteobacteria,1XRSZ@135619|Oceanospirillales 135619|Oceanospirillales T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg k141_17305_2 1278309.KB907101_gene456 1.21e-226 630.0 COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria,1XIZ8@135619|Oceanospirillales 135619|Oceanospirillales S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_17305_3 1278309.KB907101_gene455 1.11e-231 642.0 COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,1S09X@1236|Gammaproteobacteria,1XIHI@135619|Oceanospirillales 135619|Oceanospirillales M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_13190_1 1278309.KB907101_gene484 6.82e-180 520.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XH8H@135619|Oceanospirillales 135619|Oceanospirillales T FOG PAS PAC domain - - - - - - - - - - - - MCPsignal,PAS_3 k141_1331_1 1286106.MPL1_11508 5.83e-71 228.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,46067@72273|Thiotrichales 72273|Thiotrichales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_6780_1 1278309.KB907106_gene1296 1.35e-41 148.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales 135619|Oceanospirillales J SAM-dependent - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_6780_2 1286106.MPL1_00692 1.25e-111 330.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,45ZW9@72273|Thiotrichales 72273|Thiotrichales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_6780_3 1408473.JHXO01000005_gene1609 1.43e-21 98.6 COG3439@1|root,COG3439@2|Bacteria,4NH52@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_3416_1 56107.Cylst_0426 7.1e-33 131.0 COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales 1117|Cyanobacteria Q LVIVD repeat - - - - - - - - - - - - Cadherin,DUF4347,HemolysinCabind,LVIVD k141_22209_1 1449351.RISW2_01985 1.97e-31 120.0 28MU9@1|root,2ZB26@2|Bacteria,1N48H@1224|Proteobacteria,2UCZC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3726) - - - - - - - - - - - - DUF3726 k141_22209_2 1123247.AUIJ01000025_gene741 0.000464 41.6 COG4367@1|root,COG4367@2|Bacteria,1MU6T@1224|Proteobacteria,2TR0D@28211|Alphaproteobacteria 28211|Alphaproteobacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - - k141_6135_2 857087.Metme_1354 6.61e-34 132.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XDJQ@135618|Methylococcales 135618|Methylococcales F PFAM Adenylate cyclase, class-I - - 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - Adenyl_cycl_N,Adenylate_cycl k141_11086_1 1208583.COMX_04270 1.1e-08 54.3 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2JRTF@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_13216_1 1216007.AOPM01000023_gene2952 9.13e-75 265.0 COG0642@1|root,COG3300@1|root,COG2205@2|Bacteria,COG3300@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2PZR4@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_9,Response_reg k141_15979_2 713586.KB900536_gene2144 1.47e-21 93.2 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria 1236|Gammaproteobacteria MP COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_8920_1 1288826.MSNKSG1_03817 1.09e-115 363.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k141_8920_2 1288826.MSNKSG1_03812 0.0 980.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,4640D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_8920_3 1288826.MSNKSG1_03807 1.12e-102 298.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,468BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Modulates RecA activity recX GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_8920_4 1288826.MSNKSG1_03802 1.28e-39 145.0 COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,466HF@72275|Alteromonadaceae 1236|Gammaproteobacteria D Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 k141_6158_1 857087.Metme_4198 4.56e-35 125.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1XETV@135618|Methylococcales 135618|Methylococcales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_6158_2 1122194.AUHU01000015_gene2992 5.61e-41 142.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,465J2@72275|Alteromonadaceae 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_19449_1 485917.Phep_0196 2.01e-59 197.0 COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1IQEJ@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the methyltransferase superfamily ypsC - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_1358_1 713586.KB900536_gene609 2.55e-81 255.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales 135613|Chromatiales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_19557_3 913325.N799_06950 9.57e-105 310.0 COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,1RMCB@1236|Gammaproteobacteria,1X4MA@135614|Xanthomonadales 135614|Xanthomonadales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_2120_1 1288826.MSNKSG1_00651 9.75e-261 718.0 COG0840@1|root,COG0840@2|Bacteria,1RF1I@1224|Proteobacteria,1S3QF@1236|Gammaproteobacteria,46CHI@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_2120_2 1288826.MSNKSG1_00656 4.45e-251 689.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,46447@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_2120_3 1288826.MSNKSG1_00661 1.43e-311 848.0 COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,464S7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2873 O-acetylhomoserine sulfhydrylase metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - iJN746.PP_2528 Cys_Met_Meta_PP k141_2120_4 1288826.MSNKSG1_00666 1.81e-264 725.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria,466C4@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_2823_1 1278309.KB907102_gene97 4.35e-306 862.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XI12@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_2823_2 1278309.KB907102_gene98 2.54e-71 216.0 2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,1S7UG@1236|Gammaproteobacteria,1XJJ0@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_2823_3 1278309.KB907102_gene99 4.48e-81 255.0 COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria,1XHZ5@135619|Oceanospirillales 135619|Oceanospirillales P TrkA-N domain - - - - - - - - - - - - Ion_trans_2,TrkA_N k141_4911_1 305900.GV64_23205 7.89e-21 86.3 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1XJC8@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_7023_1 1232683.ADIMK_3856 9.05e-126 368.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,464TY@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases atzB - 3.5.4.32 ko:K18456 - - - - ko00000,ko01000 - - - Amidohydro_1 k141_11886_1 998674.ATTE01000001_gene2455 1.48e-56 188.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_34_1 1288826.MSNKSG1_17436 8.46e-42 155.0 28S27@1|root,2ZEE0@2|Bacteria,1RAGA@1224|Proteobacteria,1S3DZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial Ig-like domain - - - - - - - - - - - - Big_5 k141_18161_1 1278309.KB907100_gene1810 2.25e-160 458.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1XHF6@135619|Oceanospirillales 135619|Oceanospirillales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_18161_2 1278309.KB907100_gene1811 1.9e-121 353.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1XHDF@135619|Oceanospirillales 135619|Oceanospirillales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_18161_3 1278309.KB907100_gene1812 1.55e-96 281.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,1XJ86@135619|Oceanospirillales 135619|Oceanospirillales I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_18161_4 1177179.A11A3_05459 5.81e-48 172.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XHAS@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_18161_5 1278309.KB907100_gene1814 8.1e-80 240.0 COG2825@1|root,COG2825@2|Bacteria,1N89S@1224|Proteobacteria,1SEHB@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG2825 Outer membrane protein ompH - - ko:K06142 - - - - ko00000 - - - OmpH k141_18161_6 1278309.KB907100_gene1815 0.0 1028.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XHV8@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_10497_1 335284.Pcryo_1767 2.33e-16 84.7 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RRF5@1236|Gammaproteobacteria,3NR4G@468|Moraxellaceae 1236|Gammaproteobacteria T Pfam:Cache_1 - - - - - - - - - - - - CBS,HATPase_c,HisKA,PAS,dCache_1 k141_13294_1 1288826.MSNKSG1_16966 6.67e-33 117.0 COG1580@1|root,COG1580@2|Bacteria,1ND67@1224|Proteobacteria,1SDZM@1236|Gammaproteobacteria,468F7@72275|Alteromonadaceae 1236|Gammaproteobacteria N Controls the rotational direction of flagella during chemotaxis - - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_13294_2 1288826.MSNKSG1_16961 3.63e-44 143.0 COG3130@1|root,COG3130@2|Bacteria,1NKCK@1224|Proteobacteria,1SH2W@1236|Gammaproteobacteria 1236|Gammaproteobacteria J regulation of translation - - - ko:K03812 - - - - ko00000,ko03009 - - - RMF k141_13294_3 1288826.MSNKSG1_16956 0.0 996.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,464FU@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_2885 Glu_cys_ligase k141_13294_4 1288826.MSNKSG1_16951 0.0 1212.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2183 Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_9103_1 349124.Hhal_0898 6.34e-167 478.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_9103_2 95619.PM1_0201005 1.65e-104 307.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_9103_3 1268237.G114_04656 5.28e-05 45.4 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1Y3VH@135624|Aeromonadales 135624|Aeromonadales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_1430_1 497321.C664_13674 2.53e-37 130.0 2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,2KX0T@206389|Rhodocyclales 206389|Rhodocyclales S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 k141_1430_2 243924.LT42_22110 2.75e-86 262.0 COG2094@1|root,COG2094@2|Bacteria,1RGNI@1224|Proteobacteria,1S424@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the DNA glycosylase MPG family - - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco k141_1430_3 1168065.DOK_18240 2.67e-56 182.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1J5UJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - - - - - - - - - - Hexapep k141_1430_4 305700.B447_10378 8.15e-190 542.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2VHFA@28216|Betaproteobacteria,2KYJ7@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_1430_6 1158182.KB905020_gene1683 4.1e-78 244.0 COG2132@1|root,COG2132@2|Bacteria,1REHU@1224|Proteobacteria 1224|Proteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_3 k141_14693_1 754477.Q7C_2220 1.54e-58 191.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,4603H@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_14693_2 550540.Fbal_0696 5.5e-32 121.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,PGAP1 k141_16062_1 631362.Thi970DRAFT_02339 1.71e-100 304.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_16062_2 1117647.M5M_14365 1.38e-38 141.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_5644_1 69395.JQLZ01000001_gene2948 1.54e-14 78.6 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2KFCU@204458|Caulobacterales 204458|Caulobacterales EGP major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,MFS_2,Sugar_tr k141_2833_3 1410620.SHLA_15c001200 7.26e-34 121.0 2C58H@1|root,32YYI@2|Bacteria,1N7UA@1224|Proteobacteria,2UHCE@28211|Alphaproteobacteria,4BHYU@82115|Rhizobiaceae 28211|Alphaproteobacteria S NinB protein - - - - - - - - - - - - NinB k141_20995_1 754476.Q7A_2482 9.87e-20 88.2 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,460A4@72273|Thiotrichales 72273|Thiotrichales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_20995_2 395493.BegalDRAFT_0127 1.58e-70 230.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4608P@72273|Thiotrichales 72273|Thiotrichales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_17455_2 298386.PBPRB0644 1.14e-60 196.0 COG2221@1|root,COG2221@2|Bacteria 2|Bacteria C Nitrite and sulphite reductase 4Fe-4S napF - - ko:K02572 - - - - ko00000 - - - Fer4,Fer4_6,Fer4_7,NIR_SIR,PCP_red k141_11232_1 261292.Nit79A3_1354 6.82e-44 150.0 COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,2W2NC@28216|Betaproteobacteria,3744H@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF1614) - - - - - - - - - - - - DUF1614 k141_11232_2 261292.Nit79A3_0361 2.93e-68 215.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2WGYA@28216|Betaproteobacteria,374QX@32003|Nitrosomonadales 28216|Betaproteobacteria IQ Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short k141_7735_2 399795.CtesDRAFT_PD0570 4.19e-59 186.0 COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae 28216|Betaproteobacteria KT transcription factor binding - - - - - - - - - - - - - k141_7735_3 1385517.N800_11095 2.14e-50 176.0 COG0633@1|root,COG1018@1|root,COG2346@1|root,COG0633@2|Bacteria,COG1018@2|Bacteria,COG2346@2|Bacteria,1REP4@1224|Proteobacteria,1T2XC@1236|Gammaproteobacteria,1XDHE@135614|Xanthomonadales 135614|Xanthomonadales C Bacterial-like globin - - - - - - - - - - - - Bac_globin,FAD_binding_6,Fer2,NAD_binding_1 k141_12609_1 1207076.ALAT01000099_gene2466 9.09e-70 212.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1Z2RE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_12609_2 857087.Metme_4061 5.92e-24 98.2 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1XGBX@135618|Methylococcales 135618|Methylococcales NT Chemotaxis phosphatase, CheZ - - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_16078_2 460265.Mnod_7453 1.1e-15 76.3 COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TSWP@28211|Alphaproteobacteria,1JXCA@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE k141_3538_1 1026882.MAMP_01664 1.96e-86 269.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZZ6@72273|Thiotrichales 72273|Thiotrichales T PFAM response regulator receiver - - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_4214_2 626887.J057_18720 6.33e-36 130.0 COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,1S4AS@1236|Gammaproteobacteria,46AIY@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_5646_1 1163408.UU9_14830 2.44e-72 226.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1X3K3@135614|Xanthomonadales 135614|Xanthomonadales M Arabinose 5-phosphate isomerase kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_16780_1 1278309.KB907099_gene2944 1e-65 214.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1XIEB@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_7736_1 1278309.KB907099_gene2444 1.27e-88 269.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_9805_1 2340.JV46_27040 2.09e-26 103.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1JARK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_9805_2 1528106.JRJE01000005_gene1272 5.46e-96 321.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQ4H@204441|Rhodospirillales 204441|Rhodospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_9 k141_9805_3 314285.KT71_03102 3.32e-66 206.0 COG2343@1|root,COG2343@2|Bacteria,1RJ3M@1224|Proteobacteria,1RVCX@1236|Gammaproteobacteria,1JA1K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 k141_9805_4 1196323.ALKF01000203_gene3671 1.24e-56 185.0 COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,26VKU@186822|Paenibacillaceae 91061|Bacilli S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct k141_18879_1 1278309.KB907107_gene1652 1.25e-55 182.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XHXP@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_18879_2 1278309.KB907107_gene1651 1.73e-243 677.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XICE@135619|Oceanospirillales 135619|Oceanospirillales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_18879_3 1278309.KB907107_gene1650 0.0 1185.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XHEA@135619|Oceanospirillales 135619|Oceanospirillales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C k141_4927_1 1121004.ATVC01000003_gene500 2.5e-21 97.4 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria,2KPPA@206351|Neisseriales 206351|Neisseriales M Sulfatase - - - - - - - - - - - - Sulfatase k141_4927_2 1123278.KB893440_gene2665 6.69e-07 54.3 COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia 976|Bacteroidetes NU PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_15400_1 1217718.ALOU01000112_gene4314 1.61e-30 122.0 COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2WB1W@28216|Betaproteobacteria,1K4YH@119060|Burkholderiaceae 28216|Betaproteobacteria I LssY C-terminus - - - - - - - - - - - - LssY_C k141_19566_1 999411.HMPREF1092_01272 4.11e-07 53.9 COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,36GB8@31979|Clostridiaceae 186801|Clostridia P DNA binding domain, excisionase family - - 2.10.1.1 ko:K03750,ko:K07219 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N,PBP_like k141_19566_2 204773.HEAR0908 1.51e-13 65.9 2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,47552@75682|Oxalobacteraceae 28216|Betaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - k141_19566_3 187272.Mlg_1695 2.03e-166 501.0 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1WVWP@135613|Chromatiales 135613|Chromatiales T PFAM ATP-binding region - - - - - - - - - - - - HATPase_c,HisKA k141_19566_4 211586.SO_4718 1.36e-159 466.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2Q8QH@267890|Shewanellaceae 1236|Gammaproteobacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_11233_1 1123400.KB904802_gene3183 6.55e-10 58.9 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,460DH@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N k141_11233_2 999141.GME_14770 9.2e-66 205.0 COG1522@1|root,COG1522@2|Bacteria,1RB14@1224|Proteobacteria 1224|Proteobacteria K COG1522 Transcriptional regulators - - - ko:K15782 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24 k141_14713_1 1442599.JAAN01000030_gene2072 2.66e-06 52.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,1S4TD@1236|Gammaproteobacteria,1XCJ3@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_14713_2 1120963.KB894491_gene821 1.33e-31 121.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,2Q0AF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_10515_1 1254432.SCE1572_30125 1.67e-51 198.0 COG3437@1|root,COG3829@1|root,COG3852@1|root,COG4251@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X7X2@28221|Deltaproteobacteria 28221|Deltaproteobacteria T response regulator - - - - - - - - - - - - HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k141_6312_1 225937.HP15_2968 8.01e-285 788.0 COG0415@1|root,COG0415@2|Bacteria,1MX6J@1224|Proteobacteria,1RMEE@1236|Gammaproteobacteria,463Y6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family cry2 - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_6312_2 1288826.MSNKSG1_11073 5.63e-202 561.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,4652T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1230 Co Zn Cd efflux system component - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_6312_3 1288826.MSNKSG1_11068 6.61e-110 318.0 COG1999@1|root,COG1999@2|Bacteria,1RKIP@1224|Proteobacteria,1S62T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_48_1 1463821.JOGR01000010_gene3769 5.35e-39 144.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria 201174|Actinobacteria E Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_7737_1 1121004.ATVC01000050_gene913 8.19e-30 128.0 COG0784@1|root,COG2202@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2WHTA@28216|Betaproteobacteria 28216|Betaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg k141_20998_1 391615.ABSJ01000054_gene1458 7.98e-108 335.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1J5D0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria KL HELICc2 yoaA GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_11234_1 857087.Metme_2534 5.61e-82 249.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XE0E@135618|Methylococcales 135618|Methylococcales E ABC transporter - - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k141_20276_1 90814.KL370891_gene1303 1.31e-105 315.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,45ZV7@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_20276_2 396588.Tgr7_1560 3.04e-109 319.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1WXA6@135613|Chromatiales 135613|Chromatiales H riboflavin synthase, alpha subunit - - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_20276_3 472759.Nhal_2811 3.07e-143 417.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales 135613|Chromatiales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_20276_4 2340.JV46_06550 1.4e-48 160.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1J5U0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_3682_1 1120965.AUBV01000005_gene1529 6.83e-66 209.0 COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,47XY0@768503|Cytophagia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_17618_2 225937.HP15_1810 0.000248 42.4 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,464JP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K13896 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_19707_1 1123517.JOMR01000001_gene252 2.8e-18 77.4 2EGSV@1|root,33AIZ@2|Bacteria,1QR3B@1224|Proteobacteria,1RTW3@1236|Gammaproteobacteria,461FI@72273|Thiotrichales 72273|Thiotrichales S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG k141_19707_2 203122.Sde_1321 3.89e-11 64.7 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,465BT@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporters of the RND superfamily VP1286 - - ko:K07003 - - - - ko00000 - - - MMPL k141_16212_1 1278309.KB907103_gene1147 4.68e-44 152.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1RSQV@1236|Gammaproteobacteria,1XJJG@135619|Oceanospirillales 135619|Oceanospirillales K PFAM flavin reductase domain protein FMN-binding - - - - - - - - - - - - Flavin_Reduct k141_16212_2 866775.HMPREF9243_0319 7.2e-06 45.8 COG1942@1|root,COG1942@2|Bacteria,1TX6Q@1239|Firmicutes,4I636@91061|Bacilli,27EYF@186827|Aerococcaceae 91061|Bacilli S Tautomerase enzyme - - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase k141_5044_1 1278309.KB907099_gene2622 3.84e-96 291.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XHMH@135619|Oceanospirillales 135619|Oceanospirillales H molybdopterin - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_5044_2 1278309.KB907099_gene2623 9.45e-109 316.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,1XKIB@135619|Oceanospirillales 135619|Oceanospirillales H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_5044_3 1278309.KB907099_gene2624 4.59e-16 73.6 COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,1XMRX@135619|Oceanospirillales 135619|Oceanospirillales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_21162_1 1279019.ARQK01000053_gene2073 5.62e-70 228.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1WX77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_12044_1 85643.Tmz1t_0169 5.28e-92 281.0 COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,2VIXB@28216|Betaproteobacteria,2KUUG@206389|Rhodocyclales 206389|Rhodocyclales EGP of the Major Facilitator Superfamily - - - - - - - - - - - - MFS_4 k141_5809_1 1282362.AEAC466_05865 1.85e-36 142.0 COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria 1224|Proteobacteria I Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_9912_1 1278309.KB907106_gene1297 1.4e-152 434.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XIVQ@135619|Oceanospirillales 135619|Oceanospirillales C Aldo keto reductase tas - - - - - - - - - - - Aldo_ket_red k141_9912_2 1278309.KB907106_gene1296 3.9e-267 733.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales 135619|Oceanospirillales J SAM-dependent - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_9912_3 1278309.KB907106_gene1295 2.04e-80 239.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XK2F@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_9912_4 1278309.KB907106_gene1294 4.76e-237 655.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XIHM@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_9912_5 1278309.KB907106_gene1293 3.71e-40 144.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales 135619|Oceanospirillales CH hydroxylase ubiF - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_18311_1 1042375.AFPL01000044_gene1251 6.52e-79 259.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_2256_1 445970.ALIPUT_01515 2.99e-05 52.0 COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_882_1 1121923.GPUN_1141 7.12e-120 365.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_20430_1 796620.VIBC2010_07689 2.36e-35 127.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1XUUK@135623|Vibrionales 135623|Vibrionales O Protein-disulfide isomerase VP2116 - - ko:K07396 - - - - ko00000 - - - Thioredoxin_5 k141_14853_1 472759.Nhal_2203 1.83e-82 258.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1WVY3@135613|Chromatiales 135613|Chromatiales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_17619_1 1288826.MSNKSG1_11038 7.6e-123 356.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,4666C@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0826 Collagenase and related proteases yhbU - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_7159_1 1255043.TVNIR_1519 7.35e-71 223.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RNRI@1236|Gammaproteobacteria,1WYA5@135613|Chromatiales 135613|Chromatiales I Squalene phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_3683_1 395493.BegalDRAFT_3010 5.86e-36 129.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,462JT@72273|Thiotrichales 72273|Thiotrichales T Transcriptional regulatory protein, C terminal - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_8566_1 317025.Tcr_2046 1.82e-88 283.0 COG0412@1|root,COG0526@1|root,COG0412@2|Bacteria,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria,460Z2@72273|Thiotrichales 72273|Thiotrichales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,LGT k141_4381_1 314345.SPV1_00857 2.96e-61 202.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria 1224|Proteobacteria S Major facilitator Superfamily MA20_25070 - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_16213_1 1245471.PCA10_04530 6.94e-29 116.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1YF0D@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD,HD_5 k141_19030_1 1288826.MSNKSG1_17246 5.37e-63 194.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_19030_2 765913.ThidrDRAFT_0180 1.99e-113 339.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales 135613|Chromatiales U Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_11379_1 396588.Tgr7_1129 5.09e-177 530.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWJ6@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_5810_1 1278309.KB907102_gene93 3.88e-68 231.0 COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales 135619|Oceanospirillales D Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 k141_20431_1 1168067.JAGP01000001_gene710 1.17e-25 101.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,46036@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_883_1 2340.JV46_29130 1.76e-46 152.0 COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,1S4X5@1236|Gammaproteobacteria,1JAJM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K07032 - - - - ko00000 - - - Glyoxalase k141_17620_1 1242864.D187_006743 6.88e-41 149.0 COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,42ZKN@68525|delta/epsilon subdivisions,2WUTQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_2988_1 1278309.KB907099_gene2835 1.52e-73 233.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XHP4@135619|Oceanospirillales 135619|Oceanospirillales S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_2988_2 1278309.KB907099_gene2836 0.0 1102.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XH7V@135619|Oceanospirillales 135619|Oceanospirillales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_2988_3 1278309.KB907099_gene2837 4.1e-142 409.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XHDY@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N k141_6449_1 1336245.JAGO01000011_gene370 3.75e-20 91.3 COG3318@1|root,COG3318@2|Bacteria,1NA8N@1224|Proteobacteria,1S8HQ@1236|Gammaproteobacteria,1XJPH@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0149 family - - - ko:K07039 - - - - ko00000 - - - UPF0149 k141_6449_2 1499686.BN1079_01717 2e-21 94.4 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_20432_1 1249627.D779_1617 1.25e-36 133.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales 135613|Chromatiales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_19708_1 1045856.EcWSU1_02248 7.84e-99 302.0 29GEV@1|root,303CN@2|Bacteria,1MXRD@1224|Proteobacteria,1RZBE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9218_1 1278309.KB907105_gene1507 2.09e-85 253.0 2DN81@1|root,32W0Z@2|Bacteria,1MZF2@1224|Proteobacteria,1S9F7@1236|Gammaproteobacteria,1XKU8@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9218_2 1278309.KB907105_gene1506 9.89e-128 375.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1XITD@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_14854_1 626939.HMPREF9443_00738 2.26e-26 112.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4H21Y@909932|Negativicutes 909932|Negativicutes H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM k141_21785_2 398767.Glov_2944 9.26e-46 160.0 COG0834@1|root,COG0834@2|Bacteria,1N0VS@1224|Proteobacteria,42TK3@68525|delta/epsilon subdivisions,2WQS6@28221|Deltaproteobacteria 28221|Deltaproteobacteria ET Bacterial extracellular solute-binding proteins, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_21785_3 1121921.KB898706_gene2444 2.31e-36 141.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2PNTW@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k141_19031_1 1385517.N800_03475 1.48e-40 140.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1X6GZ@135614|Xanthomonadales 135614|Xanthomonadales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_18312_2 991.IW20_09795 2.17e-74 233.0 28PJM@1|root,2ZC97@2|Bacteria,4NN7Z@976|Bacteroidetes,1I1K9@117743|Flavobacteriia,2NY72@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k141_8567_1 1355374.JARU01000019_gene1953 2.29e-65 208.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions 1224|Proteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella flaB GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_7160_1 1049564.TevJSym_av00160 7.82e-187 534.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_171_1 1089552.KI911559_gene55 1.52e-31 116.0 2E65Y@1|root,330UM@2|Bacteria,1N8U3@1224|Proteobacteria,2UJ92@28211|Alphaproteobacteria,2JUNV@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k141_171_2 1123514.KB905899_gene1633 7.81e-59 197.0 COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria,461HV@72273|Thiotrichales 72273|Thiotrichales S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_11380_1 1278309.KB907103_gene1023 2.45e-102 327.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XIKY@135619|Oceanospirillales 135619|Oceanospirillales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_12046_1 1499686.BN1079_00302 2.63e-57 196.0 COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,1RP39@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily ycaD - - - - - - - - - - - MFS_1,Sugar_tr k141_12747_1 1278309.KB907108_gene1636 7.18e-73 242.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07678,ko:K20974 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475,M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE3,DUF2222,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_12747_2 1278309.KB907108_gene1635 2.25e-135 394.0 COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,1SEI1@1236|Gammaproteobacteria,1XKXH@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter substrate binding protein - - - - - - - - - - - - ABC_sub_bind k141_12747_3 1278309.KB907108_gene1634 1.03e-266 757.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RRFS@1236|Gammaproteobacteria,1XJ3N@135619|Oceanospirillales 135619|Oceanospirillales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_12747_4 1278309.KB907108_gene1633 1.08e-145 420.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1XI84@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG - 2.1.1.174 ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_5811_2 266809.PM03_06900 3.95e-12 67.4 COG0501@1|root,COG0501@2|Bacteria,1R5XJ@1224|Proteobacteria,2UMYS@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidase M48 - - - - - - - - - - - - Peptidase_M48 k141_14138_1 1163407.UU7_00015 1.06e-64 216.0 COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,1X6M6@135614|Xanthomonadales 135614|Xanthomonadales L ORF located using Blastx Glimmer Genemark - - - - - - - - - - - - DDE_Tnp_1 k141_9914_1 742817.HMPREF9449_00995 1.25e-10 64.7 COG0847@1|root,COG0847@2|Bacteria,4NP7B@976|Bacteroidetes,2FSMF@200643|Bacteroidia,22Y26@171551|Porphyromonadaceae 976|Bacteroidetes L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_17621_1 2340.JV46_24150 8.49e-20 81.3 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1J6U6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_17621_2 644801.Psest_3384 9.74e-27 107.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1Z0HA@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_7885_4 1288826.MSNKSG1_06203 6.35e-276 756.0 COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1R3UE@1224|Proteobacteria,1RRJX@1236|Gammaproteobacteria,46D70@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Sigma factor PP2C-like phosphatases rssB GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009893,GO:0010556,GO:0010604,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031647,GO:0031648,GO:0032268,GO:0032270,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0140110,GO:1903506,GO:2001141 3.1.3.3 ko:K02485,ko:K07315 - - - - ko00000,ko01000,ko02022,ko03021 - - - Response_reg,SpoIIE k141_7885_5 1288826.MSNKSG1_06208 2.66e-250 692.0 COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria,1SD6Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HD superfamily - - - ko:K06885 - - - - ko00000 - - - HD k141_18329_1 1385935.N836_11290 2.19e-12 65.9 COG4341@1|root,COG4341@2|Bacteria,1G5JU@1117|Cyanobacteria,1HB86@1150|Oscillatoriales 1117|Cyanobacteria S TIGRFAM phosphonate degradation operons associated HDIG domain protein - - - - - - - - - - - - HD k141_5827_1 207954.MED92_17299 5.98e-70 273.0 COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1T35U@1236|Gammaproteobacteria,1XJFK@135619|Oceanospirillales 135619|Oceanospirillales QU COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - k141_2268_1 326297.Sama_0278 3.04e-89 286.0 COG1100@1|root,COG1100@2|Bacteria,1MWZW@1224|Proteobacteria,1RPD6@1236|Gammaproteobacteria,2QDJM@267890|Shewanellaceae 1236|Gammaproteobacteria L Z1 domain - - - - - - - - - - - - Z1 k141_13461_1 985054.JQEZ01000003_gene1287 2.45e-75 252.0 COG0452@1|root,COG2105@1|root,COG0452@2|Bacteria,COG2105@2|Bacteria,1NZ4M@1224|Proteobacteria,2V21Z@28211|Alphaproteobacteria,4ND25@97050|Ruegeria 28211|Alphaproteobacteria H Phytochelatin synthase - - - - - - - - - - - - Ank_4,Flavoprotein,GGACT,Phytochelatin k141_14870_2 305900.GV64_02280 2.36e-13 68.6 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1XJ6Q@135619|Oceanospirillales 135619|Oceanospirillales D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA - - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_8576_1 870187.Thini_3063 9.15e-35 120.0 COG0724@1|root,COG0724@2|Bacteria,1NDEM@1224|Proteobacteria,1SFDX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM RNA recognition motif - - - - - - - - - - - - RRM_1 k141_8576_2 1385935.N836_18755 2.15e-18 82.0 2EG8Z@1|root,33A0S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_7886_1 713586.KB900536_gene2603 4.02e-13 70.9 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1WWD2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_5066_1 62928.azo2556 1.85e-67 239.0 COG0689@1|root,COG2304@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG0689@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QU09@1224|Proteobacteria 1224|Proteobacteria M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - Calx-beta,DUF4347,He_PIG,VWA_2 k141_2359_1 1123237.Salmuc_03171 3.95e-38 140.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2TTZ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria HP ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_5147_1 929556.Solca_2146 6.36e-05 52.4 COG3409@1|root,COG3409@2|Bacteria,4PPB1@976|Bacteroidetes,1IVBA@117747|Sphingobacteriia 2|Bacteria M Domain of unknown function (DUF4157) - - - - - - - - - - - - DUF4157,PG_binding_1 k141_286_1 318161.Sden_0541 1.57e-58 191.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,2QAG7@267890|Shewanellaceae 1236|Gammaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_10776_1 95619.PM1_0216770 1.13e-130 380.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria 1236|Gammaproteobacteria J An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_10776_2 59196.RICGR_0890 6.63e-77 238.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1JDQH@118969|Legionellales 118969|Legionellales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_10776_3 1121374.KB891585_gene1926 1.1e-12 67.4 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_10776_4 265072.Mfla_1005 7.73e-35 127.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,2KKBB@206350|Nitrosomonadales 206350|Nitrosomonadales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_5870_2 398580.Dshi_0266 6.32e-64 197.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_5870_3 999550.KI421507_gene81 1.89e-19 87.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_9320_2 713586.KB900536_gene2343 2.52e-159 454.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1WWD5@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_9320_3 1123242.JH636434_gene4221 1.64e-46 153.0 COG0745@1|root,COG0745@2|Bacteria,2J0FN@203682|Planctomycetes 203682|Planctomycetes KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_16286_1 911045.PSE_2964 0.000417 49.3 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_17740_1 1254432.SCE1572_12880 6.81e-27 112.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42VXX@68525|delta/epsilon subdivisions,2X6CT@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Transposase IS116/IS110/IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_18417_1 270374.MELB17_14306 1.51e-151 443.0 COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria,466JZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C k141_7272_2 998088.B565_1118 1.1e-62 203.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1Y3IS@135624|Aeromonadales 135624|Aeromonadales NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) cheZ - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_7272_3 349521.HCH_05168 9.12e-50 181.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHWH@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis protein histidine kinase and related - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_3104_1 1123237.Salmuc_00992 1.61e-21 90.5 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_8009_1 1288826.MSNKSG1_09413 3.35e-81 245.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_8009_2 1288826.MSNKSG1_09408 8.42e-104 301.0 2EA4Y@1|root,3349V@2|Bacteria,1NF5A@1224|Proteobacteria,1SFV5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PrcB C-terminal - - - - - - - - - - - - PrcB_C k141_986_1 519989.ECTPHS_06577 9.8e-64 208.0 COG5456@1|root,COG5456@2|Bacteria,1MYXM@1224|Proteobacteria,1S6WF@1236|Gammaproteobacteria,1WY96@135613|Chromatiales 135613|Chromatiales P FixH - - - - - - - - - - - - FixH k141_986_2 396588.Tgr7_2996 6.03e-26 109.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_11456_1 879212.DespoDRAFT_02241 1.46e-41 142.0 COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MKE0@213118|Desulfobacterales 28221|Deltaproteobacteria F NUDIX domain - - 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000,ko03400 - - - NUDIX k141_12872_1 207954.MED92_17600 1.73e-12 67.8 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XH9T@135619|Oceanospirillales 135619|Oceanospirillales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_12872_2 105559.Nwat_0967 8.7e-22 96.3 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales 135613|Chromatiales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_5162_1 1278309.KB907099_gene2638 1.22e-37 132.0 COG2173@1|root,COG2173@2|Bacteria,1RBFI@1224|Proteobacteria,1S38W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide ddpX - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 k141_5162_2 1278309.KB907099_gene2637 1.89e-37 126.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM98@135619|Oceanospirillales 135619|Oceanospirillales K Cold-shock' - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_5162_4 382245.ASA_2702 1.93e-68 221.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1Y4EN@135624|Aeromonadales 135624|Aeromonadales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_5162_5 1278309.KB907099_gene2635 7.5e-30 107.0 2EPBF@1|root,33GY7@2|Bacteria,1NHWE@1224|Proteobacteria,1SHUW@1236|Gammaproteobacteria,1XMPW@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8031_1 247634.GPB2148_624 4.66e-57 184.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1J5T9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_8031_2 90814.KL370891_gene1851 1.46e-22 94.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales 72273|Thiotrichales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_16301_1 697282.Mettu_3537 1.38e-80 247.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1XG1T@135618|Methylococcales 135618|Methylococcales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_1728_1 1416759.AYMR01000014_gene4132 3.36e-08 58.5 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4FKKN@85023|Microbacteriaceae 201174|Actinobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_1728_2 1123368.AUIS01000019_gene1218 1.56e-40 141.0 COG1416@1|root,COG1416@2|Bacteria,1N5DH@1224|Proteobacteria,1SF5J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_1728_3 572477.Alvin_0575 1.14e-12 67.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_3792_1 1449049.JONW01000013_gene4728 1.75e-12 72.0 COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria 1224|Proteobacteria M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag k141_9327_1 713587.THITH_08920 4.89e-94 297.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c k141_4512_1 1283300.ATXB01000001_gene2388 5.16e-28 106.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1RPGX@1236|Gammaproteobacteria,1XGXT@135618|Methylococcales 135618|Methylococcales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_4512_2 1439940.BAY1663_02120 2.87e-46 160.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans k141_5887_1 1288826.MSNKSG1_13142 7.9e-219 605.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S43R@1236|Gammaproteobacteria,468AX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_5887_2 1288826.MSNKSG1_13147 4.11e-199 553.0 COG2431@1|root,COG2431@2|Bacteria,1MYMF@1224|Proteobacteria,1RP7N@1236|Gammaproteobacteria,46APS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam:DUF340 ybjE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015179,GO:0015189,GO:0015238,GO:0015318,GO:0015562,GO:0015661,GO:0015711,GO:0015802,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0034639,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902022,GO:1902475,GO:1903401,GO:1903825,GO:1905039,GO:1990822 - - - - - - - - - - Lys_export k141_5887_3 1288826.MSNKSG1_13152 3.21e-72 216.0 COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,1SDJI@1236|Gammaproteobacteria,468PM@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved small protein - - - - - - - - - - - - DUF2288 k141_5887_4 1288826.MSNKSG1_13157 2.39e-88 259.0 COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,4684V@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Response_reg k141_5887_5 1288826.MSNKSG1_13162 3.92e-61 197.0 COG0745@1|root,COG1639@1|root,COG0745@2|Bacteria,COG1639@2|Bacteria,1RCK9@1224|Proteobacteria,1S2FB@1236|Gammaproteobacteria,46BUY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - HDOD,Response_reg k141_309_2 1288826.MSNKSG1_06438 9.66e-186 533.0 COG3170@1|root,COG3170@2|Bacteria,1N393@1224|Proteobacteria,1SFZT@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_17757_1 395961.Cyan7425_3699 0.00017 44.7 COG0642@1|root,COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1G13T@1117|Cyanobacteria,3KG2A@43988|Cyanothece 1117|Cyanobacteria T histidine kinase A domain protein - - - - - - - - - - - - Cache_3-Cache_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1 k141_17757_2 98439.AJLL01000089_gene3846 2.57e-79 251.0 COG3437@1|root,COG3437@2|Bacteria,1G2ZH@1117|Cyanobacteria,1JH9Y@1189|Stigonemataceae 1117|Cyanobacteria T HD domain - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k141_2385_1 1123399.AQVE01000005_gene910 4.25e-34 129.0 COG0697@1|root,COG0697@2|Bacteria,1R7CG@1224|Proteobacteria,1S0XU@1236|Gammaproteobacteria,462E6@72273|Thiotrichales 72273|Thiotrichales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_2385_2 1278309.KB907103_gene1108 1.56e-31 114.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XIJW@135619|Oceanospirillales 135619|Oceanospirillales H catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_5163_1 388051.AUFE01000029_gene5628 1.87e-50 176.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,1K2TE@119060|Burkholderiaceae 28216|Betaproteobacteria M N-Acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 k141_1729_1 626887.J057_23265 3.09e-59 199.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,46435@72275|Alteromonadaceae 1236|Gammaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon k141_12873_1 440512.C211_04392 4.72e-40 146.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L belongs to the nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_310_1 269799.Gmet_3085 1.06e-43 161.0 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales 28221|Deltaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg k141_19804_1 1210908.HSB1_15030 8.41e-23 102.0 COG3568@1|root,arCOG08107@2157|Archaea,2XWUI@28890|Euryarchaeota,23VCP@183963|Halobacteria 183963|Halobacteria L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_19804_2 1403819.BATR01000118_gene4206 9.89e-13 72.8 2AZX3@1|root,31S6U@2|Bacteria,46WW8@74201|Verrucomicrobia,2IWIJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF4328) - - - - - - - - - - - - DUF4328 k141_19804_4 396588.Tgr7_1064 8.36e-117 342.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1WXMH@135613|Chromatiales 135613|Chromatiales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_21262_2 1288826.MSNKSG1_09938 1.68e-179 500.0 COG0834@1|root,COG0834@2|Bacteria,1RH2S@1224|Proteobacteria,1SYZT@1236|Gammaproteobacteria,468K3@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_21262_3 1288826.MSNKSG1_09933 2e-113 326.0 COG5488@1|root,COG5488@2|Bacteria,1N2M1@1224|Proteobacteria,1S9XR@1236|Gammaproteobacteria,468JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 k141_21262_4 1288826.MSNKSG1_09928 2.24e-136 388.0 COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1S39N@1236|Gammaproteobacteria,4653X@72275|Alteromonadaceae 1236|Gammaproteobacteria GM Nucleoside-diphosphate-sugar epimerases yraR - - - - - - - - - - - HIM1,NAD_binding_10,Semialdhyde_dh k141_21262_5 1288826.MSNKSG1_09923 1.02e-135 385.0 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,4681J@72275|Alteromonadaceae 1236|Gammaproteobacteria E LysE type translocator - - - - - - - - - - - - LysE k141_21262_6 1288826.MSNKSG1_09918 3.04e-124 368.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_16302_1 382464.ABSI01000010_gene3735 1.27e-143 417.0 COG1680@1|root,COG1680@2|Bacteria,46SA8@74201|Verrucomicrobia,2IV0D@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_21933_1 187272.Mlg_1362 1.91e-63 212.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_19163_1 1177181.T9A_00441 5.52e-39 142.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XN3Q@135619|Oceanospirillales 135619|Oceanospirillales P Ammonium transporter amtB1 - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_9328_1 1149133.ppKF707_3494 3.02e-32 126.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1YDZF@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Predicted permease YjgP/YjgQ family lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_9328_2 105559.Nwat_1710 5.15e-14 72.4 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1WWXY@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_13533_1 396588.Tgr7_0696 3.52e-102 315.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales 135613|Chromatiales H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase k141_1000_2 1288826.MSNKSG1_03610 0.0 1018.0 COG4254@1|root,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,46B8N@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - FecR,LysM k141_1000_3 1288826.MSNKSG1_03605 0.0 1647.0 COG4252@1|root,COG5002@1|root,COG4252@2|Bacteria,COG5002@2|Bacteria,1MUHS@1224|Proteobacteria,1RQR2@1236|Gammaproteobacteria,469G7@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction histidine kinase - - - - - - - - - - - - CHASE2,HATPase_c,PAS_4,PAS_8 k141_1000_4 1318628.MARLIPOL_16899 3.68e-34 122.0 2DG58@1|root,2ZUJN@2|Bacteria,1P8C4@1224|Proteobacteria,1SVIB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1000_5 1232683.ADIMK_3567 1.95e-138 399.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,466XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3,FixP_N k141_1000_6 83219.PM02_17780 1.35e-46 159.0 COG3909@1|root,COG3909@2|Bacteria,1RHCJ@1224|Proteobacteria,2U95W@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG3909 Cytochrome c556 - - - - - - - - - - - - Cytochrom_C_2 k141_12874_1 1131553.JIBI01000016_gene599 3.34e-69 233.0 COG3852@1|root,COG4251@1|root,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2WHKT@28216|Betaproteobacteria 28216|Betaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA k141_3794_1 207954.MED92_00640 1.35e-106 315.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1XHJS@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_5889_1 1245469.S58_11660 1.26e-17 83.6 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2TT5N@28211|Alphaproteobacteria,3K12G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_5889_2 1504672.669785345 0.000334 42.4 COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,2VSQW@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 k141_3131_2 1288826.MSNKSG1_15247 3.16e-21 87.0 2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,1SHZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S (Lipo)protein oprI - - - - - - - - - - - Alanine_zipper k141_3131_3 1288826.MSNKSG1_15242 7.68e-161 453.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,464MH@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 k141_3131_4 1288826.MSNKSG1_15237 7.04e-158 453.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,465X3@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1030 Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_20578_1 1288826.MSNKSG1_11843 2.2e-280 778.0 2C593@1|root,2Z84R@2|Bacteria,1Q8PC@1224|Proteobacteria,1RP26@1236|Gammaproteobacteria,46680@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_311_1 1123360.thalar_03471 1.29e-36 136.0 COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_17758_2 1278309.KB907104_gene814 3.55e-47 157.0 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,1XJYG@135619|Oceanospirillales 135619|Oceanospirillales S SapC - - - - - - - - - - - - SapC k141_19805_1 1269813.ATUL01000001_gene1099 2e-05 47.8 COG0478@1|root,COG0478@2|Bacteria,1QUI1@1224|Proteobacteria,1T1ZR@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo k141_19805_2 1123073.KB899244_gene306 2.48e-28 112.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X5BS@135614|Xanthomonadales 135614|Xanthomonadales M heptosyltransferase opsX - - ko:K12982 - - - - ko00000,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_15791_1 1342302.JASC01000002_gene28 2.35e-53 176.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,3ZX3D@60136|Sulfitobacter 28211|Alphaproteobacteria I CDP-alcohol phosphatidyltransferase pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_tran_2,CDP-OH_P_transf k141_443_1 1238450.VIBNISOn1_30117 3.96e-51 175.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1S0R1@1236|Gammaproteobacteria,1Y09F@135623|Vibrionales 135623|Vibrionales S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_6647_1 765914.ThisiDRAFT_2215 4.94e-40 141.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1WWPW@135613|Chromatiales 135613|Chromatiales E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_13003_1 1485545.JQLW01000008_gene1942 1.09e-50 182.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_18520_1 367336.OM2255_09336 9.92e-42 159.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_5971_1 713586.KB900536_gene2065 3.26e-91 286.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N k141_22035_1 330214.NIDE2937 8.99e-25 96.3 2DNQI@1|root,32YKA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_4632_1 367336.OM2255_06220 1.64e-62 198.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ABC-type transport system involved in resistance to organic solvents permease component mlaE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_4632_2 1150626.PHAMO_20032 9.47e-16 75.1 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2JQ66@204441|Rhodospirillales 204441|Rhodospirillales Q COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_19910_1 1232683.ADIMK_0773 1.76e-84 272.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,469HX@72275|Alteromonadaceae 1236|Gammaproteobacteria S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_444_1 1117647.M5M_12070 1.65e-42 158.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1JA89@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_3248_1 935567.JAES01000053_gene1744 2.94e-123 359.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1XA3W@135614|Xanthomonadales 135614|Xanthomonadales L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_21366_1 1288826.MSNKSG1_07108 6.86e-176 495.0 COG3317@1|root,COG3317@2|Bacteria 2|Bacteria M Gram-negative-bacterium-type cell outer membrane assembly bamC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045229,GO:0061024,GO:0071709,GO:0071840,GO:0071944,GO:0098552,GO:0098796,GO:1990063 - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_18521_2 880070.Cycma_2669 1.13e-67 217.0 COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family rocD - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_10159_1 1123393.KB891327_gene404 2.07e-60 195.0 28HKZ@1|root,2Z7VP@2|Bacteria,1R4QW@1224|Proteobacteria,2VMSD@28216|Betaproteobacteria,1KSB6@119069|Hydrogenophilales 119069|Hydrogenophilales S Protein of unknown function (DUF3050) - - - - - - - - - - - - DUF3050 k141_19294_2 1177181.T9A_02007 1.26e-58 187.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1XI7Z@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_1825_1 1128912.GMES_4002 2.08e-99 300.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,466CP@72275|Alteromonadaceae 1236|Gammaproteobacteria S A predicted alpha-helical domain with a conserved ER motif. - - - - - - - - - - - - Alpha-E k141_1825_2 1232683.ADIMK_0990 1.6e-281 776.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_1825_3 2340.JV46_26830 2.67e-161 461.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1J59G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_1825_4 2340.JV46_26850 9.5e-09 55.5 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1J4HF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component nasD - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_1143_1 697282.Mettu_2220 1.52e-48 159.0 COG2033@1|root,COG2033@2|Bacteria,1N615@1224|Proteobacteria,1SBN9@1236|Gammaproteobacteria,1XFMZ@135618|Methylococcales 135618|Methylococcales C Desulfoferrodoxin - - - - - - - - - - - - Desulfoferrodox k141_1143_2 1278309.KB907111_gene3394 1.78e-294 810.0 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1S01Y@1236|Gammaproteobacteria,1XIYH@135619|Oceanospirillales 135619|Oceanospirillales T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4 k141_1143_3 1318628.MARLIPOL_04505 5.44e-35 127.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,469E0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21711 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_10913_1 1437824.BN940_04861 2.76e-74 227.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3T1CP@506|Alcaligenaceae 28216|Betaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_10913_2 323848.Nmul_A1884 8.32e-79 241.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3731S@32003|Nitrosomonadales 28216|Betaproteobacteria M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_8165_1 89187.ISM_03615 4.74e-21 89.7 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,2U697@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Participates in transcription elongation, termination and antitermination - - - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_16422_1 713587.THITH_01775 6.06e-112 327.0 COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria 1236|Gammaproteobacteria F COG0209 Ribonucleotide reductase, alpha subunit nrdJb - - - - - - - - - - - - k141_6648_2 243233.MCA2273 5.82e-64 203.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1XDVP@135618|Methylococcales 135618|Methylococcales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_3878_1 1207075.PputUW4_02701 3.2e-05 50.1 2DNJE@1|root,32XTK@2|Bacteria,1N282@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_5972_1 1249627.D779_2642 9.57e-68 228.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - - - - - - - - - - Cache_3-Cache_2,HAMP,MCPsignal k141_13683_1 318167.Sfri_2291 4.08e-140 426.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,2QAEU@267890|Shewanellaceae 1236|Gammaproteobacteria P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_13683_2 2340.JV46_07050 1.17e-85 258.0 COG1814@1|root,COG1814@2|Bacteria,1RBQN@1224|Proteobacteria,1S2ZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - - k141_13683_3 1122599.AUGR01000021_gene3198 3.2e-26 99.4 COG1888@1|root,COG1888@2|Bacteria,1N92Y@1224|Proteobacteria,1SD5W@1236|Gammaproteobacteria,1XQPP@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized ArCR, COG1888 - - - - - - - - - - - - DUF211 k141_15793_1 1278309.KB907104_gene822 3.15e-173 496.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Sigma54_activat k141_5310_1 1232683.ADIMK_3887 1.32e-254 701.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,4648Y@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase sgaA - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_19911_1 1232683.ADIMK_4196 2.94e-87 263.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,464SP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_4633_1 1208321.D104_07770 1.02e-77 241.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XJ0K@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter substrate-binding protein - - - - - - - - - - - - DctP k141_445_1 158500.BV97_02438 4.54e-25 102.0 COG2021@1|root,COG2021@2|Bacteria,1RDEH@1224|Proteobacteria,2U267@28211|Alphaproteobacteria,2K3DI@204457|Sphingomonadales 204457|Sphingomonadales E Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_445_2 1122137.AQXF01000002_gene94 2.79e-55 183.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K03732,ko:K11927 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_17879_2 1123503.KB908057_gene2485 0.000903 45.4 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2KG0I@204458|Caulobacterales 204458|Caulobacterales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_18522_1 335543.Sfum_3450 1.67e-38 141.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales 28221|Deltaproteobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_18522_2 765914.ThisiDRAFT_1392 2.64e-27 110.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales 135613|Chromatiales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_3249_1 1121445.ATUZ01000015_gene1934 1.01e-45 173.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales 28221|Deltaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PilJ,Response_reg k141_16423_2 398578.Daci_1478 1.65e-32 128.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria 28216|Betaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - - - - - - - - - - Radical_SAM k141_17880_1 395493.BegalDRAFT_1723 2.15e-63 212.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E ABC-type oligopeptide transport system, periplasmic component yejA GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_21367_1 313628.LNTAR_05724 6.29e-102 313.0 COG1109@1|root,COG1109@2|Bacteria 2|Bacteria G phosphoglucosamine mutase activity noeK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.13,5.4.2.8 ko:K00971,ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00361,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_10161_1 794846.AJQU01000106_gene2944 1.23e-07 59.3 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B880@82115|Rhizobiaceae 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg k141_14321_1 85643.Tmz1t_0618 9.54e-08 53.1 COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2WGTA@28216|Betaproteobacteria,2KZWK@206389|Rhodocyclales 206389|Rhodocyclales P Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_14321_2 1125863.JAFN01000001_gene1738 7.04e-69 217.0 COG0500@1|root,COG2226@2|Bacteria,1MZVH@1224|Proteobacteria 1224|Proteobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_25,Ubie_methyltran k141_14321_3 883080.HMPREF9697_03415 2.39e-33 125.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,3JTI5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P cation efflux czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_3879_1 713586.KB900536_gene2939 7.8e-89 287.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales 135613|Chromatiales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_13006_1 396595.TK90_1471 1.54e-126 365.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1WWZU@135613|Chromatiales 135613|Chromatiales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_13006_2 132113.XP_003493103.1 2.77e-53 187.0 COG0148@1|root,KOG2670@2759|Eukaryota,38C66@33154|Opisthokonta,3BE2S@33208|Metazoa,3CU4G@33213|Bilateria,41W7N@6656|Arthropoda 33208|Metazoa G It is involved in the biological process described with glycolytic process enol-1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_4634_1 1123514.KB905901_gene50 2.78e-65 206.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_18523_1 375286.mma_2202 5.28e-29 113.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,47599@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_19912_1 384765.SIAM614_16357 6.3e-98 305.0 COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,BPD_transp_1,OppC_N,oligo_HPY k141_13686_1 765914.ThisiDRAFT_0694 1.03e-78 257.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales 135613|Chromatiales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_7389_1 983545.Glaag_0853 1.57e-66 226.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_4651_1 880070.Cycma_2509 7.73e-67 228.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C k141_8174_1 1278309.KB907099_gene2621 1.19e-32 117.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XMRF@135619|Oceanospirillales 135619|Oceanospirillales H Probable molybdopterin binding domain - - - - - - - - - - - - MoCF_biosynth k141_8174_2 1278309.KB907099_gene2622 6.57e-135 393.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XHMH@135619|Oceanospirillales 135619|Oceanospirillales H molybdopterin - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_16442_1 269799.Gmet_2905 3.01e-86 269.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales 28221|Deltaproteobacteria F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_20668_1 237609.PSAKL28_35260 1.81e-08 54.3 COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,1S5H2@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q isochorismatase - - - - - - - - - - - - Isochorismatase k141_20668_2 1278309.KB907104_gene870 2.35e-71 224.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,1XIFB@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_13711_1 637905.SVI_2713 1.28e-118 360.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,2QEU3@267890|Shewanellaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_1169_1 1288826.MSNKSG1_14422 2.83e-260 713.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,4640M@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases caiA GO:0003674,GO:0003824,GO:0006066,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0016627,GO:0034308,GO:0034309,GO:0044281,GO:0044283,GO:0046165,GO:0052890,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.3.8.13,1.3.8.7 ko:K00249,ko:K04117,ko:K08297,ko:K11731 ko00071,ko00280,ko00281,ko00362,ko00410,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00281,map00362,map00410,map00640,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087,M00540 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R05619,R08089 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01893,RC02035 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_1169_2 1288826.MSNKSG1_14427 7.33e-97 283.0 COG1846@1|root,COG1846@2|Bacteria,1RB87@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator badR - - - - - - - - - - - MarR_2 k141_13026_1 1131553.JIBI01000056_gene161 4.34e-148 423.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,372US@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF692) - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_13026_2 1123393.KB891316_gene2076 3.01e-11 62.8 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,1KSYX@119069|Hydrogenophilales 119069|Hydrogenophilales S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 k141_17151_1 519989.ECTPHS_07491 2.2e-51 172.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales 135613|Chromatiales KT Response regulator of the LytR AlgR family - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_4652_1 1123401.JHYQ01000006_gene101 6.41e-55 177.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,46126@72273|Thiotrichales 72273|Thiotrichales I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) - - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA k141_21392_1 1232683.ADIMK_0998 2.17e-35 131.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,46691@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_21392_2 316275.VSAL_I2408 4.95e-59 184.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XXCB@135623|Vibrionales 135623|Vibrionales K Belongs to the P(II) protein family glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_21392_3 523791.Kkor_1079 3.75e-12 65.5 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1XI6U@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_8175_1 1117958.PE143B_0107170 1.44e-35 129.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812 DHDPS k141_16443_1 105559.Nwat_0978 2.16e-100 300.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RWHU@1236|Gammaproteobacteria,1WYF3@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161,ko:K00162,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_3900_1 999541.bgla_1g29500 1.21e-44 156.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1K1CS@119060|Burkholderiaceae 28216|Betaproteobacteria M glycosyl transferase group 1 gtrA - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_20669_1 377629.TERTU_3448 3.52e-17 85.9 COG0745@1|root,COG0745@2|Bacteria,1R52E@1224|Proteobacteria,1RRNC@1236|Gammaproteobacteria,2PPU5@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_1170_1 870187.Thini_2780 1.72e-50 164.0 COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,1S5XB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF2269 k141_15821_1 1163617.SCD_n01254 2.64e-120 359.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria 28216|Betaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_15821_2 95619.PM1_0215975 3.79e-63 198.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_12416_1 1328313.DS2_00260 1.14e-10 58.9 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,467BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 k141_10261_1 396588.Tgr7_0578 1.37e-113 344.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1WW0Q@135613|Chromatiales 135613|Chromatiales EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_10261_2 2340.JV46_26750 1.08e-17 85.9 COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria,1J68K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M membrane - - - - - - - - - - - - Porin_4 k141_8818_1 765914.ThisiDRAFT_2112 1.62e-56 182.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales 135613|Chromatiales S TIGRFAM FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P k141_6713_1 305700.B447_00220 4.68e-24 107.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales 206389|Rhodocyclales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9 k141_13786_2 247633.GP2143_12726 7.57e-74 225.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_1254_1 765911.Thivi_4328 3.7e-101 311.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_22115_1 62977.ACIAD3392 3.03e-62 205.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,3NK4V@468|Moraxellaceae 1236|Gammaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_18623_1 1286106.MPL1_05679 7.44e-91 291.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales 72273|Thiotrichales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_15121_1 1288826.MSNKSG1_14157 7.08e-165 462.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,4651C@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_11000_2 1125863.JAFN01000001_gene3416 8.21e-23 97.1 COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF374) - - - ko:K09778 - - - - ko00000 - - - DUF374 k141_17987_1 236097.ADG881_1369 3e-12 65.5 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales 135619|Oceanospirillales D COG1192 ATPases involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_17987_2 644801.Psest_3016 2.03e-41 153.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1Z03S@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG4206 Outer membrane cobalamin receptor protein btuB GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - iECB_1328.ECB_03851,iECP_1309.ECP_4183,iSF_1195.SF4048,iS_1188.S3696 Plug,TonB_dep_Rec k141_11664_1 391613.RTM1035_17022 2.63e-103 311.0 COG1593@1|root,COG1593@2|Bacteria,1MUHY@1224|Proteobacteria,2TS43@28211|Alphaproteobacteria,46NEZ@74030|Roseovarius 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_12417_1 493475.GARC_0041 6.81e-24 100.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria,467VX@72275|Alteromonadaceae 1236|Gammaproteobacteria S DTW - - - ko:K05812 - - - - ko00000 - - - DTW k141_3328_1 999547.KI421500_gene3707 2.62e-35 127.0 COG3474@1|root,COG3474@2|Bacteria,1N6WA@1224|Proteobacteria,2UHTC@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome - - - - - - - - - - - - - k141_13091_1 991905.SL003B_0246 8.91e-63 201.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,4BQ9K@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Dimerisation domain of Zinc Transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer k141_17224_1 1288826.MSNKSG1_09033 5e-119 345.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,464DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Displays ATPase and GTPase activities rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_17224_2 1288826.MSNKSG1_09028 2.81e-104 301.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,46810@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_17224_3 1288826.MSNKSG1_09023 7.12e-70 210.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,467QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1544 Ribosome-associated protein Y (PSrp-1) yhbH GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_17224_4 1288826.MSNKSG1_09018 0.0 887.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_17224_5 1288826.MSNKSG1_09013 1.44e-166 466.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,464GB@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1137 ABC-type (unclassified) transport system, ATPase component lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_17224_6 1288826.MSNKSG1_09008 1.12e-114 330.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,468RP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065 OstA k141_17224_7 1288826.MSNKSG1_09003 4.7e-134 380.0 COG3117@1|root,COG3117@2|Bacteria,1NGCC@1224|Proteobacteria,1SGDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA lptC - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC k141_17224_8 1288826.MSNKSG1_08998 2.64e-120 345.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,467ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECO26_1355.ECO26_4302 Hydrolase_3 k141_17224_9 1288826.MSNKSG1_08993 1.36e-218 605.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,464TG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Arabinose 5-phosphate isomerase kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECH74115_1262.ECH74115_4519,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSFxv_1172.SFxv_3550,iYL1228.KPN_03607,iZ_1308.Z4560 CBS,SIS k141_17224_10 1288826.MSNKSG1_08988 4.15e-189 525.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,465CS@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component mlaF GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_18624_2 1458357.BG58_02030 2.27e-07 50.4 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,1K4PP@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_11001_1 1121013.P873_03945 3.11e-17 86.7 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1X3UE@135614|Xanthomonadales 135614|Xanthomonadales S UPF0761 membrane protein rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_15876_11 1288826.MSNKSG1_03906 1.49e-105 305.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,466WN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_15876_12 1288826.MSNKSG1_03911 0.0 1179.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_3973_1 1122603.ATVI01000011_gene2067 6.45e-45 154.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1X51X@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents permease component yrbE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_3973_2 519989.ECTPHS_01719 1.28e-62 201.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1WW98@135613|Chromatiales 135613|Chromatiales Q PFAM ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_7514_1 1417296.U879_14055 3.61e-115 335.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ABC transporter mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_3346_2 572477.Alvin_0607 4.72e-83 253.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,1WW6W@135613|Chromatiales 135613|Chromatiales E subfamily IA, variant 3 - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD,HAD_2,Hydrolase k141_3346_3 713586.KB900536_gene1719 1.54e-58 184.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_15140_1 1278309.KB907104_gene835 8.03e-189 559.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XI32@135619|Oceanospirillales 135619|Oceanospirillales N ImcF-related N-terminal domain - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N,OmpA k141_6074_1 314256.OG2516_03453 3.92e-32 118.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria,2PCT6@252301|Oceanicola 28211|Alphaproteobacteria O DnaJ molecular chaperone homology domain djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_6074_2 571166.KI421509_gene445 5.65e-74 233.0 COG2374@1|root,COG2374@2|Bacteria,1NTH6@1224|Proteobacteria,2TVN3@28211|Alphaproteobacteria 28211|Alphaproteobacteria L endonuclease - - - - - - - - - - - - Exo_endo_phos k141_13109_1 290400.Jann_2646 2.21e-48 171.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_9515_2 754477.Q7C_1864 3.04e-11 66.2 COG5497@1|root,COG5497@2|Bacteria,1QXG7@1224|Proteobacteria,1S4JX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S secreted protein - - - - - - - - - - - - - k141_16540_1 396588.Tgr7_1759 6.97e-116 352.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1WW4U@135613|Chromatiales 135613|Chromatiales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_18006_1 550540.Fbal_0437 9.22e-11 67.0 COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,1RPMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Capsule polysaccharide - - - ko:K07266 - - - - ko00000 - - - Capsule_synth k141_13806_1 1278309.KB907100_gene1979 1.5e-76 238.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1XIAX@135619|Oceanospirillales 135619|Oceanospirillales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_13806_2 1278309.KB907100_gene1980 3.13e-104 301.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1XJKR@135619|Oceanospirillales 135619|Oceanospirillales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_14395_1 1461694.ATO9_02425 1.36e-52 179.0 COG0665@1|root,COG0665@2|Bacteria,1R652@1224|Proteobacteria,2TV72@28211|Alphaproteobacteria,2PD96@252301|Oceanicola 28211|Alphaproteobacteria E FAD dependent oxidoreductase solA - - - - - - - - - - - DAO k141_1933_1 1288826.MSNKSG1_00251 1.9e-36 135.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4643Q@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DEADboxA,DbpA,Helicase_C k141_1933_2 1288826.MSNKSG1_00246 3.08e-117 335.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,4678W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363 1.5.1.3 ko:K00287,ko:K18590 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020 DHFR_1 k141_1933_3 1288826.MSNKSG1_00241 7.35e-40 138.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,464KC@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422 Thymidylat_synt k141_10282_1 1125863.JAFN01000001_gene2497 3.71e-13 70.1 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42NB3@68525|delta/epsilon subdivisions,2X5VB@28221|Deltaproteobacteria 28221|Deltaproteobacteria T TIGRFAM diguanylate cyclase (GGDEF) domain - - - - - - - - - - - - GGDEF k141_10282_2 380358.XALC_0128 8.53e-31 110.0 COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,1X7FB@135614|Xanthomonadales 135614|Xanthomonadales IQ acyl carrier protein - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_10282_3 1269813.ATUL01000005_gene1976 2.49e-08 52.8 COG0764@1|root,COG0764@2|Bacteria,1NGGK@1224|Proteobacteria,1SJ6T@1236|Gammaproteobacteria,1WZPT@135613|Chromatiales 135613|Chromatiales I FabA-like domain - - - - - - - - - - - - FabA k141_18647_1 1278309.KB907105_gene1459 1.64e-123 364.0 COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,1RP0X@1236|Gammaproteobacteria,1XH6U@135619|Oceanospirillales 135619|Oceanospirillales M COG0845 Membrane-fusion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_16541_1 1190606.AJYG01000182_gene1929 4.44e-28 109.0 COG1309@1|root,COG1309@2|Bacteria,1PGUI@1224|Proteobacteria,1RW66@1236|Gammaproteobacteria,1Y1JD@135623|Vibrionales 135623|Vibrionales K transcriptional regulator - - - - - - - - - - - - - k141_542_1 1232683.ADIMK_0486 1.27e-122 371.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,4683Q@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the GSP D family cpaC - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N k141_19370_1 317025.Tcr_1800 1.59e-107 318.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_22132_1 1380394.JADL01000016_gene411 2.07e-64 221.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_22132_2 28229.ND2E_1614 1.77e-89 288.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_8839_2 1120953.AUBH01000020_gene3337 2.16e-47 155.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,4679B@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_8839_3 225937.HP15_395 3.78e-82 247.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,466EY@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_15877_1 390235.PputW619_1528 2.6e-18 84.3 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1YV8P@136845|Pseudomonas putida group 1236|Gammaproteobacteria EH PFAM aminotransferase, class IV pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Aminotran_4 k141_15877_2 32042.PstZobell_12926 4.48e-58 194.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1Z2CS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG k141_7515_1 1158165.KB898873_gene618 1.38e-109 330.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales 135613|Chromatiales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_13807_1 1232683.ADIMK_2979 4.78e-76 248.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria,4679I@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14,6.4.1.6 ko:K01474,ko:K10854 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_3974_1 1121377.KB906398_gene2097 4.29e-55 191.0 COG1640@1|root,COG1640@2|Bacteria,1WJDF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM glycoside hydrolase, family 77 malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_6076_1 666685.R2APBS1_3260 1.42e-87 282.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1X4SH@135614|Xanthomonadales 135614|Xanthomonadales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_14396_1 118173.KB235914_gene417 3.79e-10 62.4 COG2204@1|root,COG5000@1|root,COG2204@2|Bacteria,COG5000@2|Bacteria,1GPZW@1117|Cyanobacteria,1HHT6@1150|Oscillatoriales 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg k141_3347_1 1117318.PRUB_18877 3.2e-35 131.0 2DBI4@1|root,2Z9EH@2|Bacteria,1MXNH@1224|Proteobacteria,1RT1Y@1236|Gammaproteobacteria,2Q0EN@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_3347_2 298386.PBPRB1747 1.37e-37 131.0 COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,1RZBH@1236|Gammaproteobacteria,1XTMB@135623|Vibrionales 135623|Vibrionales K Repressor involved in choline regulation of the bet genes betI - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N k141_13111_1 1333998.M2A_2201 9.19e-103 314.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria,4BRFG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Conserved region in glutamate synthase - - - - - - - - - - - - Glu_synthase k141_20717_1 1288826.MSNKSG1_17641 1.36e-159 454.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,464H7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iJN746.PP_0436 S4,tRNA-synt_1b k141_20717_2 1288826.MSNKSG1_17636 3.94e-307 840.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_20717_3 1288826.MSNKSG1_17631 1.91e-94 284.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,464CU@72275|Alteromonadaceae 1236|Gammaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032 AnmK k141_17239_1 439235.Dalk_4167 2.37e-26 108.0 29M87@1|root,3085U@2|Bacteria,1RFIW@1224|Proteobacteria,42ZD2@68525|delta/epsilon subdivisions,2WTTF@28221|Deltaproteobacteria,2MMZC@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_4747_1 1249627.D779_4113 6.62e-38 142.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k141_4747_2 1453501.JELR01000002_gene510 3.47e-16 75.5 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,466G2@72275|Alteromonadaceae 1236|Gammaproteobacteria L restriction endonuclease - - - - - - - - - - - - HNH_5 k141_18648_2 1121448.DGI_0194 5.45e-42 150.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,43BFS@68525|delta/epsilon subdivisions,2WUH4@28221|Deltaproteobacteria,2MH6Z@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_12432_1 314285.KT71_01460 4e-55 177.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1J6EF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_8249_1 351348.Maqu_0312 4.07e-120 352.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,465N3@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_8249_2 1415754.JQMK01000002_gene2099 0.0 870.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 IV02_06045 - - - - - - - - - - - CP_ATPgrasp_2 k141_8249_3 1479237.JMLY01000001_gene794 5.86e-189 528.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,466CP@72275|Alteromonadaceae 1236|Gammaproteobacteria S A predicted alpha-helical domain with a conserved ER motif. - - - - - - - - - - - - Alpha-E k141_8249_4 1479237.JMLY01000001_gene793 2.54e-61 196.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1RNV8@1236|Gammaproteobacteria,465M7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_7516_1 1134474.O59_004076 4.72e-160 463.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S type VI secretion protein - - - ko:K11899,ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_6077_2 1415756.JQMY01000001_gene3153 3.42e-111 338.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2PCW9@252301|Oceanicola 28211|Alphaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_14545_1 1049564.TevJSym_aq00400 1.89e-42 146.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 ATP-synt_A k141_14545_3 243233.MCA0008 1.93e-24 96.3 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XF7Q@135618|Methylococcales 135618|Methylococcales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_20839_1 1288826.MSNKSG1_00928 3.78e-59 197.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_20839_2 1288826.MSNKSG1_00923 3.3e-149 420.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,468AP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - ko:K02494 - - - - ko00000 - - - LolB k141_20839_3 1288826.MSNKSG1_00918 1.77e-199 553.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,464HJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N k141_20839_4 1046724.KB889908_gene927 1.33e-236 654.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,464JX@72275|Alteromonadaceae 1236|Gammaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Pribosyl_synth,Pribosyltran_N k141_20839_5 1288826.MSNKSG1_00908 2.31e-145 410.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,466F7@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_20839_6 1288826.MSNKSG1_00903 2.24e-137 388.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,46699@72275|Alteromonadaceae 1236|Gammaproteobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0052689,GO:0071704,GO:0140098,GO:0140101,GO:1901564,GO:1901565,GO:1901575 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_20839_7 1288826.MSNKSG1_00898 1.39e-257 706.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,46586@72275|Alteromonadaceae 1236|Gammaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_20839_9 1396858.Q666_04955 2.5e-37 125.0 2EGUK@1|root,33AKR@2|Bacteria,1NGD7@1224|Proteobacteria,1SGN6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2042_1 1278309.KB907108_gene1631 3.32e-122 372.0 COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T245@1236|Gammaproteobacteria,1XJ38@135619|Oceanospirillales 135619|Oceanospirillales T GGDEF domain - - - - - - - - - - - - GGDEF,NMT1,SBP_bac_3 k141_17382_1 1410619.SRDD_35620 4.82e-06 47.0 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,40050@613|Serratia 1236|Gammaproteobacteria O peptidyl-prolyl cis-trans isomerase fkpB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_15225_1 1131553.JIBI01000026_gene77 4.61e-55 196.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,372ME@32003|Nitrosomonadales 28216|Betaproteobacteria I AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_7643_1 768671.ThimaDRAFT_4419 3.53e-142 430.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WWTA@135613|Chromatiales 135613|Chromatiales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_7643_2 1163617.SCD_n02265 2.83e-55 174.0 COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria 28216|Betaproteobacteria P Nitrite reductase NAD(P)H , small subunit nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske,Rieske_2 k141_9010_1 1123401.JHYQ01000013_gene616 4.13e-13 68.6 2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,461AW@72273|Thiotrichales 72273|Thiotrichales S PFAM Bacterial protein of - - - - - - - - - - - - Gcw_chp k141_9010_2 767434.Fraau_0091 3.68e-16 73.6 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1X86Q@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K09806 - - - - ko00000 - - - BMFP k141_9010_3 1415630.U771_30775 6.63e-22 94.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_4042_1 1288826.MSNKSG1_13867 6e-214 602.0 COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,4643R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1705) - - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1705,Sulfatase k141_4042_2 1288826.MSNKSG1_13872 1.23e-230 643.0 COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPJY@1236|Gammaproteobacteria,4642J@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport - - 1.14.13.22 ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 - R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko01000 - - - FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_3 k141_17383_1 1449350.OCH239_20535 1.12e-49 169.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,4KK2F@93682|Roseivivax 28211|Alphaproteobacteria E Aminotransferase class-V MA20_39235 - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_22280_1 1250232.JQNJ01000001_gene1753 1.96e-22 103.0 COG1361@1|root,COG2373@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CHU_C,DUF11 k141_11774_1 1121918.ARWE01000001_gene500 1.5e-32 131.0 COG4585@1|root,COG4585@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 k141_7644_1 697282.Mettu_0422 2.9e-84 264.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XDTS@135618|Methylococcales 135618|Methylococcales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e k141_2749_1 857087.Metme_3201 1.04e-15 80.9 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XDWV@135618|Methylococcales 135618|Methylococcales H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_2749_2 983545.Glaag_1427 9.67e-48 155.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,4683K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_20065_2 991905.SL003B_3045 1.17e-24 105.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,4BPC0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 k141_15226_1 631362.Thi970DRAFT_02916 3.46e-76 244.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales 135613|Chromatiales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_15226_2 1034943.BN1094_01372 8.86e-11 62.8 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1JCPB@118969|Legionellales 118969|Legionellales U Peptidase S24-like lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_16697_1 1288826.MSNKSG1_09118 6.77e-306 840.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,464GT@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 k141_16697_2 1288826.MSNKSG1_09123 1.9e-157 446.0 COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,46449@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleoid-associated protein ndpA - - ko:K06899 - - - - ko00000,ko03036 - - - NA37 k141_2750_1 1121939.L861_21955 1.61e-20 88.6 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1XMCH@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09926 - - - - ko00000 - - - FixH k141_17384_1 393595.ABO_2014 8.49e-16 71.6 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XKMB@135619|Oceanospirillales 135619|Oceanospirillales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_17384_2 765911.Thivi_1112 8.69e-94 291.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1WWGN@135613|Chromatiales 135613|Chromatiales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_11775_1 388401.RB2150_08558 2.99e-102 314.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,3ZI31@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria P COG0559 Branched-chain amino acid ABC-type transport system, permease components urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_674_1 1042375.AFPL01000013_gene2475 2.28e-225 625.0 COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,1RSCG@1236|Gammaproteobacteria,469ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Elongator protein 3, MiaB family, Radical SAM - - 2.5.1.77 ko:K11779 ko00680,ko01120,map00680,map01120 M00378 R09396 RC01381,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - CofC,Radical_SAM k141_674_2 1232683.ADIMK_3855 1.88e-121 352.0 COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,1S3EM@1236|Gammaproteobacteria,46DI2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx,DUF5020 k141_674_5 1479237.JMLY01000001_gene3552 3.88e-52 175.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_7645_1 269798.CHU_0715 1.06e-09 56.2 COG0824@1|root,COG0824@2|Bacteria 2|Bacteria IQ Thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 k141_7645_2 1392498.JQLH01000001_gene230 2.22e-53 182.0 COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1I06D@117743|Flavobacteriia,2PHXN@252356|Maribacter 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_14548_2 926551.KB900703_gene1000 1.22e-30 116.0 COG0438@1|root,COG0438@2|Bacteria,4NIWP@976|Bacteroidetes,1HZJU@117743|Flavobacteriia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_19485_1 1288826.MSNKSG1_09203 5.98e-48 153.0 2EICV@1|root,33C47@2|Bacteria,1NHZE@1224|Proteobacteria,1SGC1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Flg_bbr_C k141_19485_2 1288826.MSNKSG1_09208 1.44e-156 440.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,466IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_0821,iECIAI1_1343.ECIAI1_0813,iECO103_1326.ECO103_0813,iECO111_1330.ECO111_0839,iECO26_1355.ECO26_0904,iECSE_1348.ECSE_0831,iECW_1372.ECW_m0833,iEKO11_1354.EKO11_3108,iEcE24377_1341.EcE24377A_0841,iSFV_1184.SFV_0761,iSSON_1240.SSON_0757,iWFL_1372.ECW_m0833,ic_1306.c0858 AAA_26 k141_19485_3 1288826.MSNKSG1_09213 1.73e-268 736.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4655Y@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830 Aminotran_1_2 k141_19485_4 1288826.MSNKSG1_09218 4.29e-15 73.6 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_9011_1 1278309.KB907100_gene1987 1.77e-48 160.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1XJD9@135619|Oceanospirillales 135619|Oceanospirillales P Reversible hydration of carbon dioxide yadF - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_9011_2 1278309.KB907100_gene1988 3.57e-200 557.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XH3P@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_4043_1 1144305.PMI02_04966 1.21e-24 99.8 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,2K0EG@204457|Sphingomonadales 204457|Sphingomonadales L endonuclease - - - - - - - - - - - - Exo_endo_phos k141_20841_1 1288826.MSNKSG1_16606 1.16e-154 441.0 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SYZX@1236|Gammaproteobacteria,464DW@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_20841_2 1116375.VEJY3_21391 6.81e-70 216.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1SY88@1236|Gammaproteobacteria,1XZPY@135623|Vibrionales 135623|Vibrionales S Cupin domain - - - - - - - - - - - - Cupin_2 k141_20841_3 1086011.HJ01_02322 7.14e-15 73.6 COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,1IIKC@117743|Flavobacteriia,2NY71@237|Flavobacterium 976|Bacteroidetes S Alcohol dehydrogenase GroES-like domain - - - ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_16698_1 1120999.JONM01000010_gene4105 5.41e-90 286.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria 28216|Betaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_6240_1 1278309.KB907099_gene2438 3.11e-69 216.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XHRP@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N k141_6240_2 1278309.KB907099_gene2437 8.17e-317 870.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XHR2@135619|Oceanospirillales 135619|Oceanospirillales F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_14549_1 999611.KI421504_gene1379 2.66e-100 305.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,28282@191028|Leisingera 28211|Alphaproteobacteria H Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 k141_9012_1 83219.PM02_03755 5.46e-82 271.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,3ZUZ5@60136|Sulfitobacter 28211|Alphaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N k141_19486_1 991905.SL003B_3951 3.31e-98 298.0 COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_17385_1 1249627.D779_2260 5.18e-07 50.8 COG3193@1|root,COG3193@2|Bacteria,1REZG@1224|Proteobacteria,1S5K5@1236|Gammaproteobacteria,1WYDR@135613|Chromatiales 135613|Chromatiales S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_17385_2 768671.ThimaDRAFT_4604 7.97e-92 300.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_20842_1 1122225.AULQ01000001_gene1723 2.21e-08 57.0 COG3800@1|root,COG3800@2|Bacteria,4NDVH@976|Bacteroidetes,1HX9C@117743|Flavobacteriia 976|Bacteroidetes K DNA-binding protein - - - ko:K07110 - - - - ko00000,ko03000 - - - DUF2083,HTH_19,HTH_3,HTH_31,Peptidase_M78 k141_20842_2 405948.SACE_4229 2.42e-05 43.9 COG2315@1|root,COG2315@2|Bacteria 2|Bacteria V Protein conserved in bacteria - - - - - - - - - - - - YjbR k141_2043_1 1005048.CFU_3225 8.05e-28 108.0 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,472WD@75682|Oxalobacteraceae 28216|Betaproteobacteria M DNA ligase OB-like domain dnaL - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k141_2043_2 1278309.KB907099_gene2986 3.58e-68 211.0 COG0664@1|root,COG0664@2|Bacteria,1MZ52@1224|Proteobacteria,1S8CP@1236|Gammaproteobacteria,1XK7H@135619|Oceanospirillales 135619|Oceanospirillales T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_2043_3 1278309.KB907099_gene2987 2.84e-168 477.0 COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1RSNH@1236|Gammaproteobacteria,1XIGT@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_7646_2 1283300.ATXB01000001_gene2327 8.87e-97 285.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1XDWA@135618|Methylococcales 135618|Methylococcales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_15227_1 207954.MED92_02186 5.5e-125 374.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XJ2N@135619|Oceanospirillales 135619|Oceanospirillales EGP TIGRFAM Drug resistance transporter Bcr CflA subfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_9691_1 472759.Nhal_2271 3.1e-153 446.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_20088_1 1205753.A989_00005 8.96e-68 216.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1X3XY@135614|Xanthomonadales 135614|Xanthomonadales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_14586_1 472759.Nhal_3799 1.56e-65 206.0 COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales 135613|Chromatiales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_14586_2 1286631.X805_13660 3.46e-14 70.1 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1KJAC@119065|unclassified Burkholderiales 28216|Betaproteobacteria L exodeoxyribonuclease III exoA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_2067_2 697282.Mettu_3668 8.29e-87 259.0 COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,1XEK7@135618|Methylococcales 135618|Methylococcales J PFAM Elongation factor P, C-terminal - - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_2067_3 338963.Pcar_0905 2.96e-29 106.0 COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,42V3W@68525|delta/epsilon subdivisions,2WREM@28221|Deltaproteobacteria,43SRY@69541|Desulfuromonadales 28221|Deltaproteobacteria S Putative quorum-sensing-regulated virulence factor - - - ko:K09954 - - - - ko00000 - - - QSregVF_b k141_2067_4 395494.Galf_0105 2.34e-34 122.0 COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,2VVBT@28216|Betaproteobacteria,44WHQ@713636|Nitrosomonadales 28216|Betaproteobacteria O Glutathione S-transferase, N-terminal domain - - - - - - - - - - - - GST_N_3,Glutaredoxin k141_9692_1 216142.LT40_20685 4.25e-16 71.6 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_9692_2 1304275.C41B8_17204 7e-37 131.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_14587_2 1123518.ARWI01000001_gene345 9.44e-52 172.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,460B4@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_16724_1 298386.PBPRB0650 4.87e-156 463.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XU9K@135623|Vibrionales 1224|Proteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism - - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_15248_1 1049564.TevJSym_as00590 1.91e-13 66.2 2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_15248_2 585.DR95_1388 7.68e-55 184.0 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,3Z1RD@583|Proteus 1236|Gammaproteobacteria J Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_2068_1 1288826.MSNKSG1_02138 1e-59 188.0 COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,1S8AC@1236|Gammaproteobacteria,468IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG k141_2068_2 1288826.MSNKSG1_02133 6.92e-84 261.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1233 Phytoene dehydrogenase and related proteins - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8 k141_6841_1 519989.ECTPHS_08708 4.26e-45 157.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales 135613|Chromatiales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_6841_2 1056820.KB900634_gene2005 1.03e-08 54.7 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,2PMJM@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L RadC-like JAB domain radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_14588_1 1288826.MSNKSG1_07433 3.03e-183 513.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,463Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_17420_1 1286106.MPL1_01677 4.33e-88 271.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,460BE@72273|Thiotrichales 72273|Thiotrichales EGP major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_16838_7 1288826.MSNKSG1_02479 0.0 894.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,465TS@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_19618_1 391735.Veis_1547 4.5e-45 156.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,4AA97@80864|Comamonadaceae 28216|Betaproteobacteria O PFAM Thioredoxin domain - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_7813_1 1282876.BAOK01000001_gene2069 2.38e-25 106.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,4BPC0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU k141_7813_2 102129.Lepto7375DRAFT_7865 3.69e-34 129.0 COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,1H9S7@1150|Oscillatoriales 1117|Cyanobacteria P PFAM Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_7094_1 1266998.ATUJ01000004_gene1324 4.41e-22 88.2 COG5470@1|root,COG5470@2|Bacteria,1RGYN@1224|Proteobacteria,2U9AN@28211|Alphaproteobacteria,2PXC7@265|Paracoccus 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 k141_7094_2 1208323.B30_06671 6.09e-39 139.0 COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the isocitrate and isopropylmalate dehydrogenases family icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_1508_1 2340.JV46_28900 8.2e-56 176.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1J68E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin k141_15497_1 1269813.ATUL01000019_gene299 9.12e-99 310.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales 135613|Chromatiales D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_4306_1 857087.Metme_2776 5.31e-91 297.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_11313_1 1278309.KB907099_gene2424 1.47e-243 674.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XHJ5@135619|Oceanospirillales 135619|Oceanospirillales O protease - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_11313_2 1278309.KB907099_gene2425 5.47e-128 371.0 COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1RPW5@1236|Gammaproteobacteria,1XJM4@135619|Oceanospirillales 135619|Oceanospirillales H 1,4-dihydroxy-2-naphthoate octaprenyltransferase menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_11313_3 1278309.KB907099_gene2426 5.78e-284 780.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1XIKN@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_18251_2 765911.Thivi_4549 1.01e-53 176.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales 135613|Chromatiales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_10587_1 1121004.ATVC01000068_gene1672 3.49e-67 211.0 COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria,2KRK1@206351|Neisseriales 206351|Neisseriales L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_10587_2 497965.Cyan7822_4195 2.9e-21 96.7 COG1070@1|root,COG1070@2|Bacteria,1G0G6@1117|Cyanobacteria,3KGIQ@43988|Cyanothece 1117|Cyanobacteria G PFAM Carbohydrate kinase xylB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019150,GO:0019200,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_826_1 765914.ThisiDRAFT_0700 6.01e-16 76.3 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales 135613|Chromatiales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k141_826_2 1056820.KB900663_gene3848 4.65e-78 239.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,2PN57@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Ribosomal L25p family ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_826_3 717773.Thicy_1376 5.24e-20 85.1 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,460KW@72273|Thiotrichales 72273|Thiotrichales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_4307_2 713587.THITH_14820 7.49e-32 116.0 2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_1509_1 1123237.Salmuc_01451 1.78e-145 416.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_18252_1 396588.Tgr7_2622 1.05e-91 287.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales 135613|Chromatiales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_13377_1 1288826.MSNKSG1_00271 5.84e-140 403.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,4647G@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1448 Aspartate tyrosine aromatic aminotransferase phhC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_13377_2 1288826.MSNKSG1_00276 0.0 880.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,464UT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0733 Na -dependent transporters of the SNF family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_13377_3 1288826.MSNKSG1_00281 1.63e-233 642.0 COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,1RR7B@1236|Gammaproteobacteria,46A5G@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG3327 Phenylacetic acid-responsive transcriptional repressor paaX GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C k141_13377_4 1288826.MSNKSG1_00286 1.32e-269 739.0 COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,1RYM6@1236|Gammaproteobacteria,46CWQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_13377_5 1288826.MSNKSG1_00291 7.56e-187 521.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,46AIZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13377_6 1288826.MSNKSG1_00296 2.78e-227 627.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,464FK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13377_7 1288826.MSNKSG1_00301 1.38e-174 487.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,465SA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component livG - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_13377_8 225937.HP15_2703 1.04e-289 795.0 COG0410@1|root,COG3945@1|root,COG0410@2|Bacteria,COG3945@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria,46A4K@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0410 ABC-type branched-chain amino acid transport systems, ATPase component livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,Hemerythrin k141_13377_9 1288826.MSNKSG1_00311 0.0 1352.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,1RVX0@1236|Gammaproteobacteria,465EI@72275|Alteromonadaceae 1236|Gammaproteobacteria CI aldehyde dehydrogenase enoyl-CoA hydratase paaN GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1523,iECO111_1330.ECO111_1781,iECO26_1355.ECO26_1991 Aldedh,MaoC_dehydratas k141_13377_10 1288826.MSNKSG1_00316 4.71e-263 720.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RQZ8@1236|Gammaproteobacteria,4679K@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 paaE GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - iEcHS_1320.EcHS_A1479 FAD_binding_6,Fer2,NAD_binding_1 k141_13377_11 1288826.MSNKSG1_00321 2.48e-139 393.0 COG2151@1|root,COG3677@1|root,COG2151@2|Bacteria,COG3677@2|Bacteria,1RF3S@1224|Proteobacteria,1S4FY@1236|Gammaproteobacteria,46ARE@72275|Alteromonadaceae 1236|Gammaproteobacteria L metal-sulfur cluster biosynthetic enzyme paaD GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - iECSE_1348.ECSE_1476 FeS_assembly_P k141_13377_12 1288826.MSNKSG1_00326 1.25e-187 520.0 COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,1RRSG@1236|Gammaproteobacteria,469PD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phenylacetic acid catabolic protein paaC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1526,iECO111_1330.ECO111_1784,iECSE_1348.ECSE_1475,iECW_1372.ECW_m1524,iEKO11_1354.EKO11_2423,iWFL_1372.ECW_m1524 PaaA_PaaC k141_13377_13 1288826.MSNKSG1_00331 7.79e-63 192.0 COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,1S7F4@1236|Gammaproteobacteria,46B57@72275|Alteromonadaceae 1236|Gammaproteobacteria Q enzyme of phenylacetate metabolism paaB GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - iEcHS_1320.EcHS_A1476,iEcolC_1368.EcolC_2266 PaaB k141_13377_14 1288826.MSNKSG1_00336 1.37e-245 673.0 COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,1RNRN@1236|Gammaproteobacteria,469PK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phenylacetic acid catabolic protein paaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1524,iECO111_1330.ECO111_1782,iECO26_1355.ECO26_1992,iEcE24377_1341.EcE24377A_1573 PaaA_PaaC k141_13377_15 1288826.MSNKSG1_00341 1.17e-46 160.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,467QZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) paaK GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0047475,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - iECIAI1_1343.ECIAI1_1398,iECO111_1330.ECO111_1792,iECO26_1355.ECO26_2002,iECSE_1348.ECSE_1483,iECW_1372.ECW_m1532,iEKO11_1354.EKO11_2415,iEcE24377_1341.EcE24377A_1584,iWFL_1372.ECW_m1532 AMP-binding,AMP-binding_C_2 k141_828_1 391616.OA238_c01840 2.12e-30 124.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N k141_7815_1 1286106.MPL1_00747 1.23e-27 103.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,4612G@72273|Thiotrichales 72273|Thiotrichales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_20377_1 1500890.JQNL01000001_gene3517 2.7e-87 265.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1X3VJ@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_91_1 1137799.GZ78_24080 3.67e-98 295.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1XHQ1@135619|Oceanospirillales 135619|Oceanospirillales S NAD(P)-dependent - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_91_2 1122599.AUGR01000015_gene2616 3.25e-166 471.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XRGU@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_11995_1 572477.Alvin_0732 7.25e-18 80.5 COG2920@1|root,COG2920@2|Bacteria,1N6BU@1224|Proteobacteria,1S6FJ@1236|Gammaproteobacteria,1WYPC@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_17534_1 1237149.C900_04590 3.45e-89 272.0 COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated lipoprotein GldK gldK - - - - - - - - - - - FGE-sulfatase k141_2207_2 314230.DSM3645_09692 4.89e-19 88.2 COG1595@1|root,COG1595@2|Bacteria,2J08Y@203682|Planctomycetes 203682|Planctomycetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_2207_4 1049564.TevJSym_aq00360 0.0 937.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1J4X7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_2207_5 1266914.ATUK01000010_gene1129 1.34e-59 188.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria,1X18N@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_2207_6 1517416.IDAT_11080 6.43e-60 192.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,2QFMS@267893|Idiomarinaceae 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_1510_1 247633.GP2143_10232 1.75e-05 45.8 COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,1SDJI@1236|Gammaproteobacteria,1J70X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2288) - - - - - - - - - - - - DUF2288 k141_1510_2 314345.SPV1_14194 2.98e-49 161.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria 1224|Proteobacteria FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases MA20_21960 - - - - - - - - - - - HIT k141_1510_3 1120973.AQXL01000118_gene507 6.6e-18 78.2 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,27AAU@186823|Alicyclobacillaceae 91061|Bacilli L GIY-YIG catalytic domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_16851_1 1278309.KB907099_gene2438 1.19e-133 382.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XHRP@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N k141_16851_2 1278309.KB907099_gene2439 3.08e-82 244.0 COG0517@1|root,COG0517@2|Bacteria,1QTZR@1224|Proteobacteria,1S7SY@1236|Gammaproteobacteria,1XKDN@135619|Oceanospirillales 135619|Oceanospirillales S COG0517 FOG CBS domain - - - - - - - - - - - - BON,CBS k141_16851_3 1278309.KB907099_gene2440 2.62e-80 248.0 28I1X@1|root,2Z86C@2|Bacteria,1PPMS@1224|Proteobacteria,1RV76@1236|Gammaproteobacteria,1XJGV@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_21093_1 1288826.MSNKSG1_15906 5.18e-106 317.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM k141_21093_2 1288826.MSNKSG1_15901 1.54e-276 775.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465W0@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein VPA0491 - - ko:K03406,ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_21093_3 1288826.MSNKSG1_15896 0.0 894.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_21093_4 1288826.MSNKSG1_15891 1.38e-77 249.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,46428@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG2202 FOG PAS PAC domain aer-1 - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_14073_1 1278309.KB907104_gene972 2.08e-132 382.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1XJ4W@135619|Oceanospirillales 135619|Oceanospirillales H phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_14073_2 1278309.KB907104_gene973 1.93e-71 231.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1XHA5@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_2912_1 306281.AJLK01000170_gene5062 1.63e-65 221.0 COG0642@1|root,COG2205@2|Bacteria,1G0X4@1117|Cyanobacteria,1JI13@1189|Stigonemataceae 1117|Cyanobacteria T HAMP domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4 k141_18964_2 1410653.JHVC01000032_gene1036 1.68e-10 64.3 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae 186801|Clostridia L domain protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Ada_Zn_binding,Lactamase_B k141_16142_1 1144319.PMI16_03542 6.37e-24 101.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,472IA@75682|Oxalobacteraceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_16142_2 1335757.SPICUR_03285 5.16e-34 120.0 2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,1SDWS@1236|Gammaproteobacteria,1X22K@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2818) - - - - - - - - - - - - DUF2818 k141_6388_1 1041146.ATZB01000008_gene2192 2.19e-95 300.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_6388_2 1265503.KB905164_gene1780 9.44e-63 207.0 COG0760@1|root,COG0760@2|Bacteria,1NUDI@1224|Proteobacteria,1SNJZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_13378_1 1304888.ATWF01000001_gene985 1.24e-94 291.0 COG0859@1|root,COG0859@2|Bacteria,2GG3S@200930|Deferribacteres 200930|Deferribacteres M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k141_5730_1 1121935.AQXX01000122_gene5617 2.33e-10 63.5 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_15500_1 1288826.MSNKSG1_14477 3.22e-99 301.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,46AJ0@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the amidase family - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_4308_1 1278309.KB907099_gene2602 4.56e-202 568.0 COG0439@1|root,COG0439@2|Bacteria,1R5XW@1224|Proteobacteria,1RYYE@1236|Gammaproteobacteria,1XIUC@135619|Oceanospirillales 135619|Oceanospirillales I Biotin carboxylase - - - - - - - - - - - - CPSase_L_D2 k141_11314_1 75379.Tint_1281 6.96e-214 601.0 COG0446@1|root,COG0446@2|Bacteria 2|Bacteria Q pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_10590_1 765911.Thivi_1380 1.27e-25 107.0 COG1639@1|root,COG1639@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,1WZ5H@135613|Chromatiales 135613|Chromatiales T Signal transduction protein - - - - - - - - - - - - HDOD k141_9162_1 1288826.MSNKSG1_04606 0.0 1212.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4647F@72275|Alteromonadaceae 1236|Gammaproteobacteria O Molecular chaperone. Has ATPase activity htpG GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_9162_2 1288826.MSNKSG1_04611 3.83e-45 145.0 2EI8B@1|root,332D1@2|Bacteria,1N9M6@1224|Proteobacteria,1SDIK@1236|Gammaproteobacteria,46934@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2835) - - - - - - - - - - - - DUF2835 k141_9162_3 1288826.MSNKSG1_04616 7.95e-183 511.0 COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,4649D@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs dusC GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - ko:K05541 - - - - ko00000,ko01000,ko03016 - - - Dus k141_2913_1 323848.Nmul_A1339 1.43e-20 96.7 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,371U5@32003|Nitrosomonadales 28216|Betaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_7816_1 1366050.N234_03030 1.26e-17 88.2 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,1K2RV@119060|Burkholderiaceae 28216|Betaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_92_1 323261.Noc_0779 2.89e-85 265.0 COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,1RR54@1236|Gammaproteobacteria,1X0GD@135613|Chromatiales 135613|Chromatiales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_829_1 454957.IA64_12420 0.000925 41.6 COG2199@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5278@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1X6MM@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - CHASE3,GAF_2,GGDEF k141_829_2 1195236.CTER_4588 2.36e-22 88.6 2EKBF@1|root,33E1U@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_829_3 1121127.JAFA01000021_gene7991 8.91e-18 80.1 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,1K0DT@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 k141_14782_1 555778.Hneap_2072 8.55e-50 164.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1WXZY@135613|Chromatiales 135613|Chromatiales S Sulfur oxidation protein SoxY - - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_1512_1 82996.sch_17455 4.48e-18 84.0 28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,1S0XF@1236|Gammaproteobacteria 1236|Gammaproteobacteria E NHase catalyzes the hydration of various nitrile compounds to the corresponding amides - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta k141_1512_2 1131814.JAFO01000001_gene1220 0.000934 41.2 2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,3F1H7@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Nitrile hydratase, alpha chain nthA - 4.2.1.84 ko:K01721 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha k141_16143_1 1163408.UU9_13523 3.17e-120 367.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1X3EQ@135614|Xanthomonadales 135614|Xanthomonadales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt k141_9863_1 349521.HCH_00434 1.46e-93 285.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1XJ9R@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_12834_1 1266914.ATUK01000012_gene216 2.38e-133 390.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales 135613|Chromatiales C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_3768_1 1288826.MSNKSG1_08933 9.22e-92 269.0 COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1SE1A@1236|Gammaproteobacteria,468Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09908 - - - - ko00000 - - - DUF1043 k141_3768_2 1288826.MSNKSG1_08928 1.03e-116 342.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,464WH@72275|Alteromonadaceae 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_14216_1 857087.Metme_0108 1.74e-15 80.9 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_19135_1 713586.KB900536_gene1920 4.69e-90 287.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1X257@135613|Chromatiales 135613|Chromatiales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_16275_1 1288826.MSNKSG1_10928 7.76e-182 520.0 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - COX2,Cupredoxin_1 k141_12835_1 880071.Fleli_0361 8.7e-48 165.0 28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,47R7X@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_7259_2 1278309.KB907101_gene677 5.56e-44 149.0 COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,1S4MZ@1236|Gammaproteobacteria,1XK3G@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_15620_1 1049564.TevJSym_ab00830 1.28e-63 201.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1J6WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_15620_2 498211.CJA_0138 1.36e-06 50.1 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,1TB0N@1236|Gammaproteobacteria,1FHQ9@10|Cellvibrio 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY k141_19136_1 1046724.KB889921_gene118 3.64e-46 155.0 COG0664@1|root,COG0664@2|Bacteria,1NCGM@1224|Proteobacteria 1224|Proteobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_9309_1 1144305.PMI02_04164 4.24e-08 56.2 COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,2KCJX@204457|Sphingomonadales 204457|Sphingomonadales EG Belongs to the binding-protein-dependent transport system permease family - - - - - - - - - - - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_9309_2 870187.Thini_2273 1.26e-96 288.0 COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,1RYSQ@1236|Gammaproteobacteria,460PG@72273|Thiotrichales 72273|Thiotrichales H ABC-type tungstate transport system - - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 k141_9309_3 1304874.JAFY01000002_gene939 9.39e-09 56.6 COG2998@1|root,COG2998@2|Bacteria,3TA7W@508458|Synergistetes 508458|Synergistetes H PBP superfamily domain - - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 k141_3769_1 1123242.JH636436_gene3 2.6e-20 95.1 COG5433@1|root,COG5433@2|Bacteria,2IWUI@203682|Planctomycetes 203682|Planctomycetes L COG5433 Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_assoc k141_14914_3 472759.Nhal_0713 2.98e-92 274.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1WXBZ@135613|Chromatiales 135613|Chromatiales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_14914_4 396588.Tgr7_1082 4.87e-275 766.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales 135613|Chromatiales H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_3087_2 1163617.SCD_n02084 1.6e-29 110.0 2E8EX@1|root,332TA@2|Bacteria,1N97B@1224|Proteobacteria,2W47H@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_3087_3 1040987.AZUY01000010_gene4315 6.34e-14 67.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,43KPT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Cold-shock MA20_05565 - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_3087_4 765910.MARPU_09030 1.59e-62 197.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1WWMM@135613|Chromatiales 135613|Chromatiales S TIGRFAM channel protein, hemolysin III family - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_7260_1 1305737.JAFX01000001_gene854 1.96e-68 214.0 COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,47N0M@768503|Cytophagia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_274_2 765912.Thimo_2433 1.4e-44 145.0 COG3450@1|root,COG3450@2|Bacteria,1N8CD@1224|Proteobacteria,1SAR6@1236|Gammaproteobacteria,1X27X@135613|Chromatiales 135613|Chromatiales S enzyme of the cupin superfamily - - - ko:K06995 - - - - ko00000 - - - Cupin_3 k141_274_3 28258.KP05_00265 9.31e-14 73.9 COG3637@1|root,COG3637@2|Bacteria,1RJMJ@1224|Proteobacteria,1S7PC@1236|Gammaproteobacteria,1XQHX@135619|Oceanospirillales 135619|Oceanospirillales M OmpA-like transmembrane domain - - - - - - - - - - - - OMP_b-brl,OmpA_membrane k141_274_4 349521.HCH_06406 8.47e-100 311.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1XHHF@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N k141_12837_1 1402135.SUH3_10285 6.09e-91 276.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3ZV88@60136|Sulfitobacter 28211|Alphaproteobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - - ko:K11076 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - ABC_tran,TOBE_2 k141_21899_1 1163617.SCD_n02938 2.2e-28 115.0 COG5581@1|root,COG5581@2|Bacteria,1MX00@1224|Proteobacteria,2VQEK@28216|Betaproteobacteria 28216|Betaproteobacteria M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility ycgR - - - - - - - - - - - PilZ,YcgR k141_21899_2 637389.Acaty_c1519 1.77e-43 147.0 2DX2X@1|root,32V2M@2|Bacteria,1MZZC@1224|Proteobacteria,1S4WN@1236|Gammaproteobacteria,2ND0V@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - k141_21899_3 519989.ECTPHS_00655 4.31e-60 200.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWGD@135613|Chromatiales 135613|Chromatiales T response regulator - - - - - - - - - - - - Response_reg,Sigma54_activat k141_11448_1 323848.Nmul_A1668 1.16e-126 390.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,3743Q@32003|Nitrosomonadales 28216|Betaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_10767_1 1278309.KB907102_gene124 1.62e-250 704.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XHDT@135619|Oceanospirillales 135619|Oceanospirillales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_10767_2 1278309.KB907102_gene125 1.34e-257 707.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1XHQU@135619|Oceanospirillales 135619|Oceanospirillales F forms a homodimer and then a multimeric complex with NrdA - - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k141_2340_1 1562701.BBOF01000061_gene1695 1.37e-06 49.3 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,1K3DX@119060|Burkholderiaceae 28216|Betaproteobacteria EH PFAM aminotransferase, class IV dat - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_2340_2 1177181.T9A_03022 6.65e-107 322.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XI5M@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_5858_1 713586.KB900536_gene1843 6.51e-116 355.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_5858_2 935863.AWZR01000001_gene1708 9.79e-23 102.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1X4K0@135614|Xanthomonadales 135614|Xanthomonadales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_275_1 187272.Mlg_1104 4.75e-116 348.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_14915_1 90814.KL370891_gene1768 1.4e-66 209.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,460RW@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_14915_2 930169.B5T_00967 6.44e-56 176.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_977_2 1288826.MSNKSG1_06633 7.52e-182 504.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,4669P@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_2328 PAPS_reduct k141_977_3 1288826.MSNKSG1_06638 3.57e-234 644.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,464YF@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator cysB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_977_4 1288826.MSNKSG1_06643 1.31e-126 384.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AM7@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT - - ko:K03556 - - - - ko00000,ko03000 - - - GerE,TPR_19,TPR_4,TPR_8 k141_1718_1 1219045.BV98_002509 4.39e-55 189.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2K0K7@204457|Sphingomonadales 204457|Sphingomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_21254_1 1200352.A606_11475 4.92e-98 302.0 COG3239@1|root,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,22KKI@1653|Corynebacteriaceae 201174|Actinobacteria I Fatty acid desaturase alkB - 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase k141_296_1 1278309.KB907101_gene490 8.2e-111 324.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,1RMM9@1236|Gammaproteobacteria,1XH54@135619|Oceanospirillales 135619|Oceanospirillales S May be involved in the transport of PQQ or its precursor to the periplasm pqqB - - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 k141_296_2 1122201.AUAZ01000001_gene2249 3.73e-139 421.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,4668W@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional activator of acetoin glycerol metabolism - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_23,HTH_8,Sigma54_activat k141_17006_2 90813.JQMT01000001_gene1498 4.19e-99 298.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,460B1@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF455) - - - - - - - - - - - - DUF455 k141_17006_3 765912.Thimo_2012 3e-38 141.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales 135613|Chromatiales G pfam mofrl - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_8021_1 572480.Arnit_2593 6.18e-45 152.0 2AD2S@1|root,312R0@2|Bacteria,1RDQX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_8021_2 1056512.D515_04375 7.84e-12 65.1 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Glycolate oxidase, iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_13520_1 1517416.IDAT_05915 7.16e-103 307.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,2QGC6@267893|Idiomarinaceae 1236|Gammaproteobacteria M Belongs to the DegT DnrJ EryC1 family arnB - 2.6.1.104,2.6.1.59 ko:K02805,ko:K18653 - - R10698 RC00006,RC00781 ko00000,ko01000,ko01007 - - - DegT_DnrJ_EryC1 k141_13520_2 1517416.IDAT_05910 3.66e-71 218.0 COG0110@1|root,COG0110@2|Bacteria,1PH5X@1224|Proteobacteria,1RUSY@1236|Gammaproteobacteria,2QH11@267893|Idiomarinaceae 1236|Gammaproteobacteria S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep k141_13520_3 87626.PTD2_07674 6.98e-58 182.0 COG1898@1|root,COG1898@2|Bacteria,1RDA2@1224|Proteobacteria,1S4WE@1236|Gammaproteobacteria,2Q4NQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M WxcM-like, C-terminal - - - - - - - - - - - - FdtA k141_13520_4 1458275.AZ34_04130 8.87e-16 74.3 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,4ADJA@80864|Comamonadaceae 28216|Betaproteobacteria G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_6528_1 1049564.TevJSym_am00190 4.47e-72 226.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1J5GD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_6528_2 765910.MARPU_16110 4.62e-23 94.7 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales 135613|Chromatiales S integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_5156_1 1278309.KB907099_gene3143 6.51e-37 132.0 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1XIWV@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction protein - - - - - - - - - - - - HDOD k141_5156_2 1278309.KB907099_gene3142 1.74e-81 244.0 COG0847@1|root,COG0847@2|Bacteria,1RHD8@1224|Proteobacteria,1SAI6@1236|Gammaproteobacteria,1XRHP@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - k141_5156_3 1278309.KB907099_gene3141 4.13e-176 496.0 COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,1XI64@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the methyltransferase superfamily - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_5156_4 1278309.KB907099_gene3140 8.44e-145 413.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1XHG2@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_2371_1 1134474.O59_004079 4.07e-73 232.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S type VI secretion protein - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_21255_1 94624.Bpet3268 2.16e-17 79.3 COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,2VJMW@28216|Betaproteobacteria,3T24U@506|Alcaligenaceae 28216|Betaproteobacteria S ABC transporter, ATP-binding protein - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_21255_2 443152.MDG893_08345 3.67e-48 163.0 COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,1RY3E@1236|Gammaproteobacteria,46430@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the binding-protein-dependent transport system permease family - - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 k141_10784_2 305900.GV64_21245 5.38e-36 132.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XH2P@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_21921_1 1288826.MSNKSG1_01813 1.41e-51 168.0 2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,1SEPF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21921_2 1288826.MSNKSG1_01818 2.24e-196 543.0 COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,1RNZ8@1236|Gammaproteobacteria,469PC@72275|Alteromonadaceae 1236|Gammaproteobacteria C Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_21921_3 1288826.MSNKSG1_01823 1.69e-96 281.0 COG3832@1|root,COG3832@2|Bacteria,1N94B@1224|Proteobacteria,1SFH4@1236|Gammaproteobacteria 1236|Gammaproteobacteria J glyoxalase III activity - - - - - - - - - - - - Polyketide_cyc2 k141_21921_4 1288826.MSNKSG1_01828 4.24e-224 617.0 COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,1NFCU@1224|Proteobacteria,1T3BN@1236|Gammaproteobacteria,46CNE@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - AraC_binding,HTH_AraC k141_21921_5 1288826.MSNKSG1_01833 0.0 970.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,465NX@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_21921_6 1288826.MSNKSG1_01838 5.02e-275 753.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,4640M@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases acdA - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_21921_7 1288826.MSNKSG1_01843 1.11e-161 454.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,4667F@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 k141_17007_1 1367847.JCM7686_0466 6.61e-13 67.8 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,2PVGV@265|Paracoccus 28211|Alphaproteobacteria EH Belongs to the PAPS reductase family. CysH subfamily cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - DUF934,PAPS_reduct k141_17007_2 1402135.SUH3_02315 9.82e-104 315.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,3ZWFA@60136|Sulfitobacter 28211|Alphaproteobacteria P Sulfite reductase cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_19796_1 1279017.AQYJ01000027_gene1597 6.27e-30 118.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,465SW@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes tonB3 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_19796_2 396588.Tgr7_2910 3.58e-33 119.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1WX8T@135613|Chromatiales 135613|Chromatiales K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_4506_1 1232683.ADIMK_1288 1.59e-132 379.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,4650X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_4613_2 713587.THITH_14510 1.71e-41 140.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S6RN@1236|Gammaproteobacteria,1X27A@135613|Chromatiales 135613|Chromatiales K MraZ protein, putative antitoxin-like mraZ - - ko:K03925 - - - - ko00000 - - - MraZ k141_17859_1 1288826.MSNKSG1_17436 4.24e-137 417.0 28S27@1|root,2ZEE0@2|Bacteria,1RAGA@1224|Proteobacteria,1S3DZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial Ig-like domain - - - - - - - - - - - - Big_5 k141_17859_2 1288826.MSNKSG1_17441 1.06e-155 446.0 COG2067@1|root,COG2067@2|Bacteria,1RA6W@1224|Proteobacteria,1RPD8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X k141_5964_2 663610.JQKO01000003_gene1467 2.43e-44 160.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2U43Z@28211|Alphaproteobacteria,3NCZF@45404|Beijerinckiaceae 28211|Alphaproteobacteria P TrkA-N domain - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N k141_17882_1 396588.Tgr7_3033 2.08e-61 211.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_6651_1 1288826.MSNKSG1_17291 1.14e-229 634.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,465EC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_1827_1 765910.MARPU_15335 2.87e-37 152.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2,sCache_2 k141_1149_1 519989.ECTPHS_02194 1.42e-50 177.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales 135613|Chromatiales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_10915_1 1236959.BAMT01000003_gene469 4.74e-21 89.0 COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria,2KMZ5@206350|Nitrosomonadales 206350|Nitrosomonadales NU PFAM type II secretion system - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl k141_10915_2 1470593.BW43_00130 4.95e-16 76.6 COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,1T58B@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl k141_12313_1 1288826.MSNKSG1_10313 9.63e-137 388.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria,466CS@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the GST superfamily gstA - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_3 k141_19913_1 1278309.KB907099_gene2770 3.27e-302 841.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XHJ4@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_3255_1 395493.BegalDRAFT_0073 3.57e-62 206.0 COG0247@1|root,COG0247@2|Bacteria,1QV1F@1224|Proteobacteria,1T3FB@1236|Gammaproteobacteria,463UZ@72273|Thiotrichales 72273|Thiotrichales C 4Fe-4S dicluster domain - - - - - - - - - - - - - k141_3255_2 62928.azo1131 1.91e-24 98.6 297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,2VIEE@28216|Betaproteobacteria,2KWQQ@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_13007_1 1123393.KB891328_gene530 3.74e-38 135.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,1KRSX@119069|Hydrogenophilales 119069|Hydrogenophilales O prohibitin homologues - - - - - - - - - - - - Band_7 k141_13007_2 396588.Tgr7_0365 1.18e-59 185.0 COG2920@1|root,COG2920@2|Bacteria 2|Bacteria P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_13007_3 323261.Noc_2450 2.1e-24 115.0 COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k141_15046_1 1278309.KB907102_gene39 1.58e-90 275.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1XHYN@135619|Oceanospirillales 135619|Oceanospirillales D Reduces the stability of FtsZ polymers in the presence of ATP zapE - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_15046_2 1278309.KB907102_gene38 8.71e-145 410.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XHZU@135619|Oceanospirillales 135619|Oceanospirillales M effector of murein hydrolase - - - - - - - - - - - - LrgB k141_15046_3 1278309.KB907102_gene37 2.43e-55 175.0 COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,1SDBW@1236|Gammaproteobacteria,1XM48@135619|Oceanospirillales 135619|Oceanospirillales S LrgA family - - - - - - - - - - - - LrgA k141_15046_4 697282.Mettu_3985 9.18e-50 169.0 COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,1XEYM@135618|Methylococcales 135618|Methylococcales S Uncharacterized protein family UPF0016 - - - - - - - - - - - - UPF0016 k141_15046_5 1488328.JMCL01000018_gene564 5e-38 137.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_15046_6 1004785.AMBLS11_10675 9.38e-18 77.4 COG1977@1|root,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12 ko:K03636,ko:K03752,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395,R11581 RC02507 ko00000,ko00001,ko01000 - - iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775 ThiS k141_15046_7 1278309.KB907102_gene34 9.37e-205 577.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XHMH@135619|Oceanospirillales 135619|Oceanospirillales H molybdopterin - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_15046_8 1278309.KB907102_gene33 2.03e-72 220.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XJ5T@135619|Oceanospirillales 135619|Oceanospirillales H May be involved in the biosynthesis of molybdopterin - - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_21371_1 754477.Q7C_2186 2.01e-205 598.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales 72273|Thiotrichales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_1828_1 996637.SGM_2115 6.2e-26 111.0 COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria 201174|Actinobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_1150_1 1134474.O59_004068 4.16e-104 333.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria N type VI secretion protein icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_12314_1 314270.RB2083_1985 4.85e-113 335.0 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2TSKS@28211|Alphaproteobacteria 28211|Alphaproteobacteria G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11,3.1.3.37 ko:K01086,ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_2501_1 2340.JV46_24990 1.92e-101 310.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1J50Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,STAS_2,Sulfate_transp k141_11572_2 1288826.MSNKSG1_02303 6.8e-139 394.0 COG3145@1|root,COG3145@2|Bacteria,1N5HB@1224|Proteobacteria,1S23P@1236|Gammaproteobacteria,46AQ8@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3145 Alkylated DNA repair protein alkB GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008198,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016705,GO:0016706,GO:0032451,GO:0033554,GO:0034641,GO:0035510,GO:0035511,GO:0035513,GO:0035515,GO:0035552,GO:0035553,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043734,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044728,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0070579,GO:0070988,GO:0070989,GO:0071704,GO:0080111,GO:0090304,GO:0140098,GO:1901360 1.14.11.33 ko:K03919 - - - - ko00000,ko01000,ko03400 - - - 2OG-FeII_Oxy_2 k141_11572_3 1288826.MSNKSG1_02298 0.0 1739.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,465R9@72275|Alteromonadaceae 1236|Gammaproteobacteria T HD domain - - - - - - - - - - - - GAF_3,HD_5,dCache_1 k141_11572_4 1288826.MSNKSG1_02293 3.6e-169 474.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,4673B@72275|Alteromonadaceae 1236|Gammaproteobacteria O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_11572_5 1288826.MSNKSG1_02288 1.25e-134 382.0 COG2020@1|root,COG2020@2|Bacteria,1RCWQ@1224|Proteobacteria,1TBAQ@1236|Gammaproteobacteria,467N2@72275|Alteromonadaceae 1236|Gammaproteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_11572_6 1396858.Q666_02235 4.93e-305 847.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,464KE@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_11572_7 1288826.MSNKSG1_02268 6.23e-59 197.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1R8MU@1224|Proteobacteria,1S01I@1236|Gammaproteobacteria,469GR@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GGDEF k141_5980_1 398580.Dshi_0105 4.99e-85 258.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2TRE6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S OST-HTH/LOTUS domain MA20_15040 - - - - - - - - - - - NYN,OST-HTH k141_7393_1 472759.Nhal_1115 3.3e-157 473.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_5315_1 1232683.ADIMK_2083 4.15e-109 327.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RPU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_5315_2 216595.PFLU_1336 4.62e-08 53.1 COG1028@1|root,COG1028@2|Bacteria,1RA3U@1224|Proteobacteria,1RREY@1236|Gammaproteobacteria,1YUKZ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria IQ RmlD substrate binding domain - - - - - - - - - - - - adh_short_C2 k141_13008_1 1122137.AQXF01000002_gene46 1.44e-110 329.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria 28211|Alphaproteobacteria E phospho-2-dehydro-3-deoxyheptonate aldolase aroF GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 k141_17883_1 626887.J057_19155 7.35e-55 199.0 COG1073@1|root,COG1073@2|Bacteria,1NVTC@1224|Proteobacteria,1RNXQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1073 Hydrolases of the alpha beta superfamily - - - - - - - - - - - - Lipase_bact_N k141_22037_1 1049564.TevJSym_af00130 1.71e-142 409.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1J5VE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O DnaJ-class molecular chaperone cbpA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_22037_2 323261.Noc_1383 6.56e-26 99.8 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1WZDM@135613|Chromatiales 135613|Chromatiales K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_22037_3 1163617.SCD_n00017 5.35e-158 451.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,2VPIS@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_22037_5 395493.BegalDRAFT_3426 8.87e-52 172.0 COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAES@1236|Gammaproteobacteria,462TI@72273|Thiotrichales 72273|Thiotrichales O DNA-J related protein - - - - - - - - - - - - DNAJ_related,DnaJ k141_22037_6 326427.Cagg_0034 1.94e-10 68.2 COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity exsG - - - - - - - - - - - GGDEF,HAMP,HATPase_c,HWE_HK,HisKA_2,PAS,PAS_3,PAS_4,PAS_9 k141_1829_1 768706.Desor_0953 5.38e-38 145.0 COG1204@1|root,COG1204@2|Bacteria,1TUMQ@1239|Firmicutes,25NI3@186801|Clostridia,2664K@186807|Peptococcaceae 186801|Clostridia L DEAD DEAH box helicase - - - - - - - - - - - - - k141_14324_1 1049564.TevJSym_av00270 5.41e-37 141.0 COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1J539@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. prsK - - - - - - - - - - - GAF_2,HATPase_c k141_14324_2 1049564.TevJSym_av00260 1.25e-24 102.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains prsR - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_8169_1 396588.Tgr7_1275 4.42e-57 188.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1WWD8@135613|Chromatiales 135613|Chromatiales O Belongs to the HypD family - - - ko:K04654 - - - - ko00000 - - - HypD k141_6652_2 1049564.TevJSym_bn00120 4.81e-27 104.0 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1JAMF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Phosphoribosyl transferase domain pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_10167_1 1515746.HR45_14760 7.2e-38 149.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein VPA0491 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_18527_1 1278309.KB907102_gene200 3.38e-145 420.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XI8E@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_18527_2 1278309.KB907102_gene199 1.61e-90 291.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XHNQ@135619|Oceanospirillales 135619|Oceanospirillales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,ResIII,SNF2_N k141_5316_1 391613.RTM1035_16632 9.06e-46 158.0 COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,46PRS@74030|Roseovarius 28211|Alphaproteobacteria H COG0404 Glycine cleavage system T protein (aminomethyltransferase) - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C,SnoaL_2 k141_5316_2 744985.HIMB59_00001660 1.25e-34 122.0 COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria,4BSRJ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC k141_7394_1 1123247.AUIJ01000005_gene470 6.85e-10 60.5 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE_1 - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_16429_1 1122201.AUAZ01000001_gene2493 5.79e-147 423.0 COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,1RMUP@1236|Gammaproteobacteria,46CP2@72275|Alteromonadaceae 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain - - 3.5.3.3 ko:K08688 ko00260,ko00330,ko01100,map00260,map00330,map01100 - R01566 RC00548,RC00549 ko00000,ko00001,ko01000 - - - Creatinase_N,Peptidase_M24 k141_16429_2 1122599.AUGR01000005_gene1938 1.03e-29 109.0 COG4392@1|root,COG4392@2|Bacteria 2|Bacteria E branched-chain amino acid - - - - - - - - - - - - AzlD k141_13690_1 1288826.MSNKSG1_17271 3.1e-90 273.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_13690_2 1288826.MSNKSG1_17276 4.91e-135 383.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,466HT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Ham1p_like k141_13690_3 1288826.MSNKSG1_17281 5.53e-99 288.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,468AH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4426) PP5099 - - - - - - - - - - - DUF4426 k141_13690_4 1288826.MSNKSG1_17286 5.79e-148 416.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,466CD@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW k141_13690_5 1288826.MSNKSG1_17291 6.86e-42 146.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,465EC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_19915_1 1288826.MSNKSG1_08163 4.15e-116 339.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_5317_1 497321.C664_17657 5.25e-37 132.0 COG3090@1|root,COG3090@2|Bacteria,1PUDS@1224|Proteobacteria,2W6BR@28216|Betaproteobacteria 28216|Betaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_13009_1 1278309.KB907111_gene3395 1.4e-40 143.0 COG1278@1|root,COG1463@1|root,COG1278@2|Bacteria,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,1XKPV@135619|Oceanospirillales 135619|Oceanospirillales Q Protein of unknown function (DUF3465) - - - - - - - - - - - - DUF3465 k141_1153_1 1095769.CAHF01000022_gene432 9.64e-37 142.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_7395_1 1123518.ARWI01000001_gene1639 4e-47 172.0 COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Parallel beta-helix repeats - - - - - - - - - - - - Cu-oxidase_3 k141_22038_1 644107.SL1157_2207 1.09e-81 249.0 COG0483@1|root,COG0483@2|Bacteria,1R3TP@1224|Proteobacteria,2U4FB@28211|Alphaproteobacteria,4NCEX@97050|Ruegeria 28211|Alphaproteobacteria G Belongs to the inositol monophosphatase superfamily - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_12315_1 1158165.KB898874_gene1816 7.01e-18 88.2 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZKN@1236|Gammaproteobacteria,1X0QN@135613|Chromatiales 135613|Chromatiales T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS,PAS_9 k141_12315_2 999419.HMPREF1077_01414 2.83e-48 167.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,2FMZ9@200643|Bacteroidia,22WMK@171551|Porphyromonadaceae 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_16430_1 1500893.JQNB01000001_gene361 6.54e-119 346.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_3257_1 1278309.KB907102_gene63 1.94e-189 539.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1XI7C@135619|Oceanospirillales 135619|Oceanospirillales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_20656_1 411463.EUBVEN_00517 6.64e-07 50.1 2ED08@1|root,336X7@2|Bacteria,1VI3E@1239|Firmicutes,24TJC@186801|Clostridia 186801|Clostridia S COG NOG20805 non supervised orthologous group - - - - - - - - - - - - - k141_15799_1 1278309.KB907113_gene3325 0.0 1043.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XHCD@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_15799_2 491952.Mar181_3364 3.31e-45 149.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1XJXD@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_13691_1 1121396.KB893057_gene2489 4.6e-42 152.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42N3Y@68525|delta/epsilon subdivisions,2WJFS@28221|Deltaproteobacteria,2MJEA@213118|Desulfobacterales 28221|Deltaproteobacteria M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k141_13691_2 1121405.dsmv_2057 2.92e-79 242.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,2MJ28@213118|Desulfobacterales 28221|Deltaproteobacteria V PFAM ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1830_1 519989.ECTPHS_09323 5.92e-128 373.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1WX3A@135613|Chromatiales 135613|Chromatiales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_4637_1 1278309.KB907099_gene2678 3.37e-59 195.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XHQK@135619|Oceanospirillales 135619|Oceanospirillales E Serine dehydratase beta chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_4637_3 1278309.KB907099_gene2677 1.57e-198 551.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XIXR@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) - - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - Formyl_trans_N k141_4637_4 1278309.KB907099_gene2676 2.24e-136 388.0 COG4583@1|root,COG4583@2|Bacteria,1PURC@1224|Proteobacteria,1S1XP@1236|Gammaproteobacteria,1XS6I@135619|Oceanospirillales 135619|Oceanospirillales E sarcosine oxidase - - 1.5.3.1 ko:K00305 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxG k141_4637_5 1278309.KB907099_gene2675 5.86e-75 247.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,1XIC3@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the GcvT family soxA - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_6654_1 1189612.A33Q_0328 3.42e-21 94.0 COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP k141_11594_1 1123070.KB899249_gene298 1.02e-22 97.8 COG0714@1|root,COG0714@2|Bacteria,46S9V@74201|Verrucomicrobia,2ITT6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_20738_1 1278309.KB907100_gene2246 3.45e-95 290.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,1XJ7U@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type Zn2 transport system, periplasmic component surface adhesin - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k141_20738_2 1278309.KB907100_gene2247 1.65e-100 293.0 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1XJKD@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the Fur family - - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR k141_20738_3 1278309.KB907100_gene2248 1.51e-151 430.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1XHPH@135619|Oceanospirillales 135619|Oceanospirillales P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC - - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_20738_4 1278309.KB907100_gene2249 2.22e-144 411.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1XIN4@135619|Oceanospirillales 135619|Oceanospirillales P COG1108 ABC-type Mn2 Zn2 transport systems, permease components znuB - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 k141_9547_1 644966.Tmar_1401 7.09e-10 60.8 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,24AIF@186801|Clostridia 186801|Clostridia C PFAM Cysteine-rich domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_3371_2 314287.GB2207_04702 1.12e-31 120.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1J4NJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG2897 Rhodanese-related sulfurtransferase rhdA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_15925_1 395495.Lcho_1464 1.2e-111 360.0 COG0642@1|root,COG0784@1|root,COG1956@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1956@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGMB@28216|Betaproteobacteria,1KPMJ@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Cache domain - - 2.7.13.3 ko:K11527 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1 k141_10320_1 675814.VIC_002177 1.71e-38 150.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XV3Y@135623|Vibrionales 135623|Vibrionales NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,PAS_8,PAS_9 k141_10320_2 1168067.JAGP01000001_gene744 1.76e-113 335.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,461ZM@72273|Thiotrichales 72273|Thiotrichales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_10320_3 765914.ThisiDRAFT_0315 4.09e-88 265.0 COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,1WVY2@135613|Chromatiales 135613|Chromatiales NT Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_10320_4 1049564.TevJSym_aa01060 2.69e-157 452.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1J5DG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_19399_1 580332.Slit_1713 3.15e-23 97.4 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,2W0AA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_6765_1 1249627.D779_4118 4.46e-70 230.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_5472_1 1121897.AUGO01000001_gene1599 1.2e-14 75.9 COG2932@1|root,COG2932@2|Bacteria,4NP41@976|Bacteroidetes,1I1YH@117743|Flavobacteriia,2NVJ8@237|Flavobacterium 976|Bacteroidetes K Peptidase S24-like - - - - - - - - - - - - Peptidase_S24,Phage_CI_repr k141_5472_2 1196028.ALEF01000061_gene1097 1.91e-26 107.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli 91061|Bacilli T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase M1-535 - 2.7.13.3 ko:K07683,ko:K07777 ko02020,map02020 M00478,M00483 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,PAS_3,PAS_8,PAS_9 k141_16568_1 1288826.MSNKSG1_04461 9.17e-235 663.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46511@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_2628_1 595494.Tola_0159 5.86e-15 72.8 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1Y4CX@135624|Aeromonadales 135624|Aeromonadales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_2628_2 1085623.GNIT_0228 1.57e-11 72.0 COG2199@1|root,COG3706@2|Bacteria,1MZQ8@1224|Proteobacteria,1RS4B@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase yneF - 2.7.7.65 ko:K21020 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - GGDEF,MASE1 k141_22178_1 1207058.L53_03770 0.000212 44.7 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,43WQQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_22178_2 743720.Psefu_2521 5.46e-111 341.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,1YXN5@136845|Pseudomonas putida group 1236|Gammaproteobacteria MP PFAM OmpA MotB domain protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_18695_1 1487923.DP73_12445 2.6e-37 148.0 COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1TQKW@1239|Firmicutes,24D67@186801|Clostridia,26441@186807|Peptococcaceae 186801|Clostridia T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,dCache_1 k141_18695_2 396588.Tgr7_0038 1.04e-57 194.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_14432_1 713586.KB900536_gene2263 3.75e-37 130.0 COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_14432_2 243164.DET1250 6.7e-12 61.6 2A3IT@1|root,30S1U@2|Bacteria,2GAWI@200795|Chloroflexi,34DHE@301297|Dehalococcoidia 301297|Dehalococcoidia S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_11053_1 1122214.AQWH01000010_gene2804 2.15e-23 92.4 COG2314@1|root,COG2314@2|Bacteria,1N8Y8@1224|Proteobacteria,2UFKT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TM2 domain - - - - - - - - - - - - TM2 k141_11053_3 35703.DQ02_09225 1.15e-17 82.4 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,3WWY2@544|Citrobacter 1236|Gammaproteobacteria H Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_3994_1 864073.HFRIS_000780 1.22e-63 211.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,472BG@75682|Oxalobacteraceae 28216|Betaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 k141_10321_1 411684.HPDFL43_02475 2.2e-16 78.2 COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2TR9B@28211|Alphaproteobacteria,43GUA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family xylH GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10544 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - BPD_transp_2 k141_10321_2 266779.Meso_3114 1.36e-32 123.0 COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria,43H4T@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G ABC transporter substrate-binding protein xylF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - ko:K10543 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - Peripla_BP_4 k141_11699_1 1479237.JMLY01000001_gene2998 6.95e-32 118.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SBN6@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Pilin (bacterial filament) pilA - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_11699_2 1288826.MSNKSG1_08848 0.0 1088.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464KS@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_11699_3 1288826.MSNKSG1_08853 1.88e-33 124.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,465E5@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG1459 Type II secretory pathway, component PulF pilC GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_13154_1 391616.OA238_c46930 3.84e-79 242.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_13154_2 367336.OM2255_09821 3.46e-55 176.0 COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2U94M@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator petP - - - - - - - - - - - MarR_2 k141_9549_1 935863.AWZR01000005_gene2198 1.33e-10 61.2 COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,1RPI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - Glyco_hydro_43 k141_9549_2 926559.JoomaDRAFT_2666 3.22e-41 144.0 COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1HWN3@117743|Flavobacteriia 976|Bacteroidetes F Nudix hydrolase - - - - - - - - - - - - NUDIX k141_12473_1 396588.Tgr7_2900 2.96e-79 273.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_19400_1 519989.ECTPHS_01184 3.08e-68 220.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_19400_2 1260251.SPISAL_00305 2.23e-07 52.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_20015_1 2340.JV46_02810 1.28e-66 213.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1J5JA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_13839_1 1288826.MSNKSG1_18310 1.03e-215 606.0 COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,468KN@72275|Alteromonadaceae 1236|Gammaproteobacteria U Sporulation related domain damX GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR k141_13839_2 1288826.MSNKSG1_18305 3.04e-257 706.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,46412@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3389,iBWG_1329.BWG_3080,iECDH10B_1368.ECDH10B_3564,iECDH1ME8569_1439.ECDH1ME8569_3268,iECNA114_1301.ECNA114_3486,iEcDH1_1363.EcDH1_0324,iJO1366.b3389,iJR904.b3389,iY75_1357.Y75_RS20275 DHQ_synthase k141_13839_3 1318628.MARLIPOL_17473 2.83e-115 332.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,467A5@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_13839_4 1288826.MSNKSG1_18295 0.0 1259.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_13839_5 1288826.MSNKSG1_18290 8.03e-128 363.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,467HE@72275|Alteromonadaceae 1236|Gammaproteobacteria NU pilus assembly protein PilP pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_20761_1 484022.Fphi_0611 3.83e-81 247.0 COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 k141_7549_1 1042375.AFPL01000013_gene2430 5.27e-47 162.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,46592@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_22199_1 1278309.KB907112_gene3339 2.3e-100 303.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_22199_2 1278309.KB907112_gene3338 0.0 1524.0 COG0247@1|root,COG0277@1|root,COG1152@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1152@2|Bacteria,1MU6Y@1224|Proteobacteria,1RM7Z@1236|Gammaproteobacteria,1XH99@135619|Oceanospirillales 135619|Oceanospirillales C FAD linked oxidases, C-terminal domain - - - ko:K18930 - - - - ko00000 - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8 k141_5487_1 62928.azo2825 1.04e-11 64.3 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,2KXQK@206389|Rhodocyclales 206389|Rhodocyclales H Molybdopterin biosynthesis - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_5487_2 96561.Dole_3234 7.64e-97 297.0 COG0388@1|root,COG0388@2|Bacteria,1RENA@1224|Proteobacteria,42VUB@68525|delta/epsilon subdivisions,2WS8Y@28221|Deltaproteobacteria,2MMNH@213118|Desulfobacterales 28221|Deltaproteobacteria H PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_5487_4 1123393.KB891316_gene2013 2.79e-48 155.0 COG0025@1|root,COG0025@2|Bacteria,1QTZ5@1224|Proteobacteria,2WGIC@28216|Betaproteobacteria 28216|Betaproteobacteria P Zn-finger in ubiquitin-hydrolases and other protein - - - - - - - - - - - - zf-UBP k141_5487_5 1173025.GEI7407_1751 4.02e-120 356.0 COG1294@1|root,COG1294@2|Bacteria,1G0PM@1117|Cyanobacteria,1H7ZJ@1150|Oscillatoriales 1117|Cyanobacteria C TIGRFAM cytochrome d oxidase, subunit II (cydB) cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iAPECO1_1312.cydB,iJN678.cydB Cyt_bd_oxida_II k141_5487_6 335543.Sfum_3051 1.9e-127 379.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42P0J@68525|delta/epsilon subdivisions,2WJJQ@28221|Deltaproteobacteria,2MSJK@213462|Syntrophobacterales 28221|Deltaproteobacteria C PFAM cytochrome bd ubiquinol oxidase, subunit I - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_15959_1 381666.H16_A2407 5.33e-55 184.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2VHVN@28216|Betaproteobacteria,1K0DV@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component dppC2 - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k141_2657_1 105559.Nwat_1853 9.96e-119 351.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_14450_1 697282.Mettu_1364 3.09e-13 73.6 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XERT@135618|Methylococcales 1236|Gammaproteobacteria U SMART ATPase, AAA type, core mshM - - ko:K12283 - - - - ko00000,ko02044 - - - AAA_22 k141_10351_1 870187.Thini_4009 2.49e-134 392.0 COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,1RSFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C protein alpha chain nifD - 1.18.6.1 ko:K02586 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - Oxidored_nitro k141_19419_1 1188256.BASI01000002_gene3161 2.15e-44 146.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,3FDEJ@34008|Rhodovulum 28211|Alphaproteobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_18720_1 292415.Tbd_1652 2.7e-84 254.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,1KRJ7@119069|Hydrogenophilales 119069|Hydrogenophilales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_13858_1 94122.Shewana3_0022 7.49e-40 147.0 COG2199@1|root,COG2199@2|Bacteria,1NYG9@1224|Proteobacteria,1RV5M@1236|Gammaproteobacteria,2QD9V@267890|Shewanellaceae 1236|Gammaproteobacteria T Protoglobin - - - - - - - - - - - - GGDEF,Protoglobin k141_16600_2 644283.Micau_2143 1.94e-38 155.0 COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria 201174|Actinobacteria E Oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3 k141_20762_1 90813.JQMT01000001_gene1306 5.74e-40 145.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,460WQ@72273|Thiotrichales 72273|Thiotrichales S Belongs to the GcvT family - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_5488_2 1283300.ATXB01000001_gene1394 4.12e-16 81.6 COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,1S2TH@1236|Gammaproteobacteria,1XEVE@135618|Methylococcales 135618|Methylococcales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_7550_1 247634.GPB2148_3881 4.81e-142 423.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1J4U2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_22200_2 32057.KB217478_gene4587 0.000404 43.9 COG4106@1|root,COG4106@2|Bacteria,1G3BF@1117|Cyanobacteria,1HJHC@1161|Nostocales 1117|Cyanobacteria S PFAM Methyltransferase domain - - 2.1.1.144 ko:K00598 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_18072_1 555778.Hneap_1927 1.62e-123 370.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWES@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_8886_1 207954.MED92_13868 2.64e-195 545.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,1RPKH@1236|Gammaproteobacteria,1XJ1G@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter substrate-binding protein - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_8886_2 675812.VHA_002863 3.75e-66 205.0 2DKV6@1|root,30FIA@2|Bacteria,1RFQ5@1224|Proteobacteria,1S4BE@1236|Gammaproteobacteria,1Y2A5@135623|Vibrionales 135623|Vibrionales S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_8886_3 207954.MED92_13878 4.26e-306 842.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XHN7@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctA - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_16601_1 1229172.JQFA01000002_gene2253 6.56e-82 254.0 COG0451@1|root,COG0451@2|Bacteria,1G0TM@1117|Cyanobacteria,1H797@1150|Oscillatoriales 1117|Cyanobacteria GM NAD dependent epimerase dehydratase family sqdB - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k141_14451_1 1168065.DOK_13779 5.12e-24 99.8 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1J587@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the ribF family ribF GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0025,iJN746.PP_0602 FAD_syn,Flavokinase k141_17295_1 1288826.MSNKSG1_16021 1.91e-43 148.0 2EKRM@1|root,33EFD@2|Bacteria,1NMVY@1224|Proteobacteria,1SITC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17295_2 1288826.MSNKSG1_16016 2.38e-294 802.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria,46664@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_17295_3 1288826.MSNKSG1_16011 2.33e-80 248.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1RPNI@1236|Gammaproteobacteria,46AES@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_1972_1 1423144.Gal_02264 9.31e-37 139.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2TST4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k141_1972_2 375451.RD1_3034 2.28e-08 56.2 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2P1TS@2433|Roseobacter 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k141_15160_2 314345.SPV1_04088 1.37e-72 224.0 COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria 1224|Proteobacteria S Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_16,PrmA k141_11072_1 1288826.MSNKSG1_12377 3.64e-149 424.0 COG4796@1|root,COG4796@2|Bacteria 2|Bacteria U Type ii and iii secretion system protein - - - - - - - - - - - - Secretin,Secretin_N k141_11072_2 1288826.MSNKSG1_12382 3.69e-239 660.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,4656M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_11072_3 1288826.MSNKSG1_12387 0.0 1853.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_713_1 203122.Sde_1459 2.39e-08 55.1 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,464HQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO k141_11167_1 1278309.KB907104_gene830 1.13e-144 411.0 2C6PZ@1|root,32V0V@2|Bacteria,1R3NU@1224|Proteobacteria,1T6A9@1236|Gammaproteobacteria,1XQAH@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20928_1 349521.HCH_01662 8.63e-71 224.0 COG1776@1|root,COG2201@1|root,COG1776@2|Bacteria,COG2201@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,1XJ9I@135619|Oceanospirillales 135619|Oceanospirillales NT response regulator - - - - - - - - - - - - CheC,Response_reg k141_20928_2 94122.Shewana3_0570 1.97e-62 201.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,2Q8RF@267890|Shewanellaceae 1236|Gammaproteobacteria T PFAM GGDEF domain containing protein - - - - - - - - - - - - GGDEF,PAS,PAS_4 k141_21620_1 1121035.AUCH01000004_gene412 1.61e-36 135.0 2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,2KYBI@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_21620_2 556268.OFAG_01427 2.43e-56 180.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,474FN@75682|Oxalobacteraceae 28216|Betaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_16744_1 1123054.KB907716_gene150 9.25e-12 61.6 2DQ92@1|root,335D5@2|Bacteria,1NG6T@1224|Proteobacteria,1SFWE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_16744_2 472759.Nhal_0882 1.63e-68 210.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales 135613|Chromatiales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_16744_3 279714.FuraDRAFT_2339 1.26e-18 82.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,2KRPT@206351|Neisseriales 206351|Neisseriales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_16744_4 220341.16503839 5.69e-10 56.6 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,3ZMH4@590|Salmonella 1236|Gammaproteobacteria S RnfH family Ubiquitin rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_14660_1 335543.Sfum_2391 1.3e-44 162.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria 28221|Deltaproteobacteria V PFAM ABC transporter - - - ko:K01990,ko:K01992,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC2_membrane_3,ABC_tran k141_5589_1 1131553.JIBI01000068_gene1055 9.69e-20 92.0 COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,2WFIE@28216|Betaproteobacteria,372YN@32003|Nitrosomonadales 28216|Betaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_20228_1 1288826.MSNKSG1_10703 5.16e-71 219.0 COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,1SASV@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG1651 Protein-disulfide isomerase - - - - - - - - - - - - Thioredoxin_4 k141_20228_2 1288826.MSNKSG1_10698 1.3e-35 129.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_11_1 1521187.JPIM01000126_gene240 1.16e-09 64.3 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - 3.4.21.10 ko:K01317 - - - - ko00000,ko01000,ko01002,ko04131 - - - CARDB,DUF5011,HYR,Laminin_G_3,VCBS k141_4892_1 754476.Q7A_668 7.86e-100 304.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,4606R@72273|Thiotrichales 72273|Thiotrichales L ATPase (AAA - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_4892_2 1055815.AYYA01000067_gene1622 1.62e-09 58.2 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1RYHF@1236|Gammaproteobacteria,3NKC7@468|Moraxellaceae 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA k141_5590_1 762376.AXYL_02217 9.66e-49 171.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,3T1E8@506|Alcaligenaceae 28216|Betaproteobacteria S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_9072_1 1499967.BAYZ01000009_gene5347 7.47e-67 217.0 COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria 2|Bacteria S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_9072_2 686578.AFFX01000001_gene1572 1.61e-09 55.8 2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,1SGBH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2970) - - - - - - - - - - - - DUF2970 k141_8380_2 396588.Tgr7_2124 8.47e-106 345.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales 135613|Chromatiales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_4192_1 765914.ThisiDRAFT_2568 8.64e-37 130.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1WYGU@135613|Chromatiales 135613|Chromatiales N flagellar protein FliS - - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_16043_1 1323663.AROI01000007_gene2681 2.7e-82 255.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_14661_1 314278.NB231_16288 1.63e-65 207.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales 135613|Chromatiales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_6983_1 754477.Q7C_206 9.7e-183 528.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,460AS@72273|Thiotrichales 72273|Thiotrichales C radical SAM protein YgiQ - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_12563_1 314264.ROS217_22162 9.58e-95 283.0 COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VFYH@28211|Alphaproteobacteria,46PK3@74030|Roseovarius 28211|Alphaproteobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_16745_1 749414.SBI_09006 2.32e-11 67.4 COG5412@1|root,COG5412@2|Bacteria,2I383@201174|Actinobacteria 201174|Actinobacteria M Domain of unknown function (DUF4157) - - - - - - - - - - - - DUF4157 k141_1408_1 930169.B5T_03664 8.06e-88 271.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,1XHYJ@135619|Oceanospirillales 135619|Oceanospirillales S Bile acid sodium symporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_21621_2 472759.Nhal_2220 9.17e-115 348.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_2797_1 580332.Slit_1395 1.07e-33 141.0 COG2202@1|root,COG3447@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WDA@713636|Nitrosomonadales 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,MASE1,PAS_3,PAS_9 k141_10466_1 443152.MDG893_17787 5.54e-69 238.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4667H@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_7,TPR_8 k141_20229_1 1288826.MSNKSG1_18495 9.71e-162 480.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 k141_4893_1 742818.HMPREF9451_00145 1.25e-31 124.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CUF1@84998|Coriobacteriia 84998|Coriobacteriia V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_13955_1 927658.AJUM01000037_gene2422 8.01e-38 141.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,3XJVP@558415|Marinilabiliaceae 976|Bacteroidetes C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg porA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N k141_13955_2 1211813.CAPH01000012_gene318 1.5e-71 224.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,22URR@171550|Rikenellaceae 976|Bacteroidetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain oorB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C k141_715_1 1288826.MSNKSG1_05326 1.7e-22 92.8 COG1296@1|root,COG1296@2|Bacteria,1RG4P@1224|Proteobacteria,1T05Q@1236|Gammaproteobacteria,46AUP@72275|Alteromonadaceae 1236|Gammaproteobacteria E branched-chain amino acid permease (azaleucine resistance) - - - - - - - - - - - - AzlC k141_715_2 1288826.MSNKSG1_05321 6.93e-64 196.0 COG1687@1|root,COG1687@2|Bacteria,1NC1B@1224|Proteobacteria,1SGFW@1236|Gammaproteobacteria,46CC8@72275|Alteromonadaceae 1236|Gammaproteobacteria E branched-chain amino acid azlD - - - - - - - - - - - AzlD k141_715_3 1288826.MSNKSG1_05316 2.87e-134 385.0 COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,466VU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_9073_1 1279009.ADICEAN_01027 2.08e-07 52.0 COG0226@1|root,COG0226@2|Bacteria,4NKND@976|Bacteroidetes,47PVA@768503|Cytophagia 976|Bacteroidetes P Type IX secretion system membrane protein PorP/SprF - - - - - - - - - - - - PorP_SprF k141_9073_2 269798.CHU_0169 2.35e-69 216.0 COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,47JYP@768503|Cytophagia 976|Bacteroidetes H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_8381_1 317025.Tcr_1610 4.27e-58 192.0 COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,1S74G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_6287_1 439235.Dalk_2155 2.9e-13 77.8 COG2931@1|root,COG2931@2|Bacteria,1R094@1224|Proteobacteria 1224|Proteobacteria Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - UnbV_ASPIC,VCBS k141_20230_1 287.DR97_1223 5.14e-104 316.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1YEWY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_21622_1 696747.NIES39_D02520 2.68e-88 278.0 COG2192@1|root,COG2192@2|Bacteria,1G1FV@1117|Cyanobacteria,1H9E9@1150|Oscillatoriales 1117|Cyanobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k141_9769_1 243159.AFE_2986 3.92e-06 48.5 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,2NDTJ@225057|Acidithiobacillales 225057|Acidithiobacillales S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 k141_9769_2 1049564.TevJSym_ad01300 2.04e-16 77.8 COG2153@1|root,COG2153@2|Bacteria,1N7TN@1224|Proteobacteria,1SCI6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein acetylation - - - - - - - - - - - - - k141_8382_1 1415780.JPOG01000001_gene1043 0.000837 47.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1X45E@135614|Xanthomonadales 135614|Xanthomonadales S permease perM - - - - - - - - - - - AI-2E_transport k141_11870_1 1288826.MSNKSG1_17970 3.74e-39 134.0 COG4968@1|root,COG4968@2|Bacteria,1R2E5@1224|Proteobacteria,1T5NI@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K10924 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_11870_2 1288826.MSNKSG1_17965 1.14e-110 319.0 COG4970@1|root,COG4970@2|Bacteria,1QXGD@1224|Proteobacteria,1T3BJ@1236|Gammaproteobacteria,46D53@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl k141_4193_1 323261.Noc_2773 8.11e-14 70.5 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales 135613|Chromatiales P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_4193_2 713586.KB900536_gene3001 7.53e-168 478.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_19541_1 1123367.C666_04410 2.3e-07 51.6 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,2KUGP@206389|Rhodocyclales 206389|Rhodocyclales S ABC transporter abcZ - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_19541_3 2340.JV46_23290 3.85e-77 234.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1J5QA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_12564_2 1232683.ADIMK_0134 9.74e-109 318.0 COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,4678V@72275|Alteromonadaceae 1236|Gammaproteobacteria S glutamine amidotransferases - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k141_12564_3 1129794.C427_2251 2.08e-31 118.0 28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,4641D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k141_5591_1 1485544.JQKP01000004_gene505 8.99e-154 441.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales 28216|Betaproteobacteria P Ammonium Transporter Family - - - ko:K03320,ko:K06580 - - - - ko00000,ko02000,ko04090 1.A.11,1.A.11.4 - - Ammonium_transp k141_18838_3 1353537.TP2_00500 2.6e-100 303.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TR8F@28211|Alphaproteobacteria,2XP18@285107|Thioclava 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_18838_4 1049564.TevJSym_ae00660 7.83e-33 124.0 COG0398@1|root,COG0607@1|root,COG0398@2|Bacteria,COG0607@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P SNARE associated Golgi protein ydjX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Rhodanese,SNARE_assoc k141_3496_1 1278309.KB907103_gene1172 1.02e-22 95.5 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XJ26@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_3496_2 522306.CAP2UW1_2752 8.37e-69 216.0 COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,2VH4Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Phenylacetic acid degradation protein PaaY paaY - - ko:K02617,ko:K08279 - - - - ko00000 - - - Hexapep k141_3496_3 55601.VANGNB10_cII0014 1.06e-89 269.0 COG2910@1|root,COG2910@2|Bacteria,1MV9B@1224|Proteobacteria,1S0ZG@1236|Gammaproteobacteria,1XWBV@135623|Vibrionales 135623|Vibrionales S NmrA-like family - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 k141_3496_4 55601.VANGNB10_cII0013c 2.07e-20 88.6 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1XTV8@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_3496_5 1123279.ATUS01000001_gene1802 3.95e-36 125.0 COG2963@1|root,COG2963@2|Bacteria,1N04F@1224|Proteobacteria,1S6GJ@1236|Gammaproteobacteria,1JBF8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Helix-turn-helix domain - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_3496_6 1123279.ATUS01000001_gene1803 2.34e-130 375.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,1JBYI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DDE domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_Tnp_1,rve,rve_3 k141_2119_1 1026882.MAMP_03079 2.91e-248 714.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZWR@72273|Thiotrichales 72273|Thiotrichales PT Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS_9 k141_2119_3 1232683.ADIMK_3629 3.23e-67 216.0 COG2252@1|root,COG2252@2|Bacteria,1QU00@1224|Proteobacteria,1T1JI@1236|Gammaproteobacteria,464UK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Xanthine uracil vitamin C permease - - - - - - - - - - - - Xan_ur_permease k141_14681_3 744872.Spica_0271 2.21e-31 112.0 COG0727@1|root,32S46@2|Bacteria,2J9D0@203691|Spirochaetes 203691|Spirochaetes S Fe-S-cluster oxidoreductase - - - ko:K06940 - - - - ko00000 - - - - k141_1425_1 1249627.D779_0089 1.95e-118 359.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales 135613|Chromatiales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_9097_1 395961.Cyan7425_2548 1.13e-23 102.0 COG1262@1|root,COG4301@1|root,COG1262@2|Bacteria,COG4301@2|Bacteria,1G2JI@1117|Cyanobacteria,3KFTD@43988|Cyanothece 1117|Cyanobacteria S TIGRFAM methyltransferase - - - - - - - - - - - - Methyltransf_33 k141_9097_2 187303.BN69_3440 7.89e-83 259.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,36XC2@31993|Methylocystaceae 28211|Alphaproteobacteria S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase,Methyltransf_33 k141_20399_1 1288826.MSNKSG1_06048 2.28e-111 326.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,4653C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_12694_1 1278309.KB907106_gene1273 6.82e-258 715.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XHDN@135619|Oceanospirillales 135619|Oceanospirillales FP Belongs to the GppA Ppx family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA k141_12694_2 1278309.KB907106_gene1274 4.01e-72 216.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1XJXC@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_12694_3 1278309.KB907106_gene1275 2.04e-292 799.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1XHZA@135619|Oceanospirillales 135619|Oceanospirillales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_12694_4 1278309.KB907106_gene1276 7.03e-210 588.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,1XIJM@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k141_15520_1 1112217.PPL19_23222 1.91e-43 144.0 COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K11022 ko05134,map05134 - - - ko00000,ko00001,ko02042 - - - - k141_15520_2 1278309.KB907100_gene1932 2.11e-11 60.8 28NXJ@1|root,2ZBV4@2|Bacteria,1RD2V@1224|Proteobacteria,1S3XU@1236|Gammaproteobacteria,1XKYM@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0325 family - - - - - - - - - - - - DUF3461 k141_16882_1 396588.Tgr7_1150 2.54e-91 278.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1WWQK@135613|Chromatiales 135613|Chromatiales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_21116_1 1318628.MARLIPOL_04070 7.96e-194 542.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RY77@1236|Gammaproteobacteria,469BV@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxidoreductase FAD-binding domain antC - - ko:K11311 ko00627,ko01120,map00627,map01120 M00637 R00823,R00825 RC00192 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_21116_2 1318628.MARLIPOL_04075 5.55e-95 279.0 COG5517@1|root,COG5517@2|Bacteria,1RDSS@1224|Proteobacteria,1S5CV@1236|Gammaproteobacteria,46AEW@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Ring hydroxylating beta subunit antB - 1.14.12.1 ko:K05600 ko00627,ko01120,map00627,map01120 M00637 R00823,R00825 RC00192 br01602,ko00000,ko00001,ko00002,ko01000 - - - Ring_hydroxyl_B k141_21116_3 1318628.MARLIPOL_04080 2.51e-133 389.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RRDH@1236|Gammaproteobacteria,4680W@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ring hydroxylating alpha subunit (catalytic domain) antA - 1.14.12.1,1.14.13.239 ko:K05599,ko:K22443 ko00627,ko01120,map00627,map01120 M00637 R00823,R00825 RC00192 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k141_847_1 754436.JCM19237_4935 1.51e-10 66.6 COG3266@1|root,COG3266@2|Bacteria,1QIXK@1224|Proteobacteria,1TGU0@1236|Gammaproteobacteria,1Y1TM@135623|Vibrionales 135623|Vibrionales U Sporulation related domain - - - - - - - - - - - - SPOR k141_120_1 314262.MED193_21244 1.61e-100 301.0 COG1879@1|root,COG1879@2|Bacteria,1NZGQ@1224|Proteobacteria,2TUC3@28211|Alphaproteobacteria,2P376@2433|Roseobacter 28211|Alphaproteobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_4 k141_2229_2 626887.J057_14165 2.17e-09 58.9 COG3203@1|root,COG3203@2|Bacteria,1N04Q@1224|Proteobacteria 1224|Proteobacteria M PFAM porin Gram-negative type - - - ko:K08720,ko:K09476 ko01501,ko02020,ko05111,map01501,map02020,map05111 M00746 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.1.1.1,1.B.1.2.1 - - Porin_4 k141_18267_1 666681.M301_1701 8.06e-49 175.0 COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM EAL domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9 k141_12007_1 443144.GM21_0436 9.9e-24 104.0 COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria 1224|Proteobacteria M Ompa motb domain protein - - - - - - - - - - - - OmpA k141_12007_2 443144.GM21_0435 5.46e-18 84.0 COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM conserved repeat domain protein - - - - - - - - - - - - DUF11,SdrD_B k141_18980_1 1121939.L861_23975 3.99e-50 185.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XHGK@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA - 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_4335_1 1278309.KB907107_gene1710 2.08e-167 487.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XH92@135619|Oceanospirillales 135619|Oceanospirillales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_8511_1 1123392.AQWL01000001_gene1450 1.38e-45 164.0 COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria,1KRYT@119069|Hydrogenophilales 119069|Hydrogenophilales T HDOD domain - - - - - - - - - - - - GGDEF,HDOD,Response_reg k141_8511_2 1121015.N789_14005 1.88e-20 86.7 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,1XC90@135614|Xanthomonadales 135614|Xanthomonadales S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_16883_1 349124.Hhal_0580 8.07e-64 203.0 COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales 135613|Chromatiales L PFAM HhH-GPD - - - ko:K07457 - - - - ko00000 - - - HhH-GPD k141_7121_1 713586.KB900536_gene813 1.3e-105 316.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWG5@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K09695 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC_tran k141_7121_2 1123253.AUBD01000004_gene1046 1.1e-12 67.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,1X4H4@135614|Xanthomonadales 135614|Xanthomonadales S Alpha beta - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 k141_848_1 296591.Bpro_0557 5.62e-26 102.0 COG3090@1|root,COG3090@2|Bacteria,1QU8D@1224|Proteobacteria,2WGIS@28216|Betaproteobacteria,4AFRK@80864|Comamonadaceae 28216|Betaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_848_2 314232.SKA53_00080 1.79e-36 134.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2P9BJ@245186|Loktanella 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_5758_1 367336.OM2255_03227 1.34e-39 134.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_5758_2 367336.OM2255_03232 1.33e-60 190.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_18268_1 1214065.BAGV01000061_gene987 4.97e-70 223.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-Transferase yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0044424,GO:0044464,GO:0055114 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373 GST_C_2,GST_N_2 k141_121_1 745411.B3C1_10422 9.59e-16 72.4 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1J6NQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit1 - - - - - - - - - - - HIT k141_121_2 314285.KT71_07129 3.52e-22 90.5 COG2827@1|root,COG2827@2|Bacteria,1QJ9D@1224|Proteobacteria,1TH7Z@1236|Gammaproteobacteria,1JAXE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Containing a URI domain - - - - - - - - - - - - GIY-YIG k141_121_3 926550.CLDAP_06540 1.19e-06 51.6 COG1985@1|root,COG1985@2|Bacteria 2|Bacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate - - - - - - - - - - - - RibD_C k141_5000_1 1300350.DSW25_02585 1.84e-136 398.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,3ZVIX@60136|Sulfitobacter 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_11339_1 883080.HMPREF9697_01394 4.43e-72 236.0 COG0028@1|root,COG0028@2|Bacteria,1R743@1224|Proteobacteria,2U4KA@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_6406_1 686340.Metal_0445 7.83e-226 653.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE8,EAL,GGDEF,HAMP k141_6406_3 1232683.ADIMK_2334 3.64e-19 87.4 COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,1T3G2@1236|Gammaproteobacteria 1236|Gammaproteobacteria H TonB dependent receptor - - - ko:K02014,ko:K16089 - - - - ko00000,ko02000 1.B.14,1.B.14.1,1.B.14.10 - - Plug,TonB_dep_Rec k141_17569_1 1278309.KB907103_gene1153 8.92e-140 420.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_9882_1 1278309.KB907101_gene789 1.61e-98 289.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1XJAG@135619|Oceanospirillales 135619|Oceanospirillales NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_5017_1 1278309.KB907111_gene3399 7.98e-122 357.0 COG4974@1|root,COG4974@2|Bacteria,1PZTE@1224|Proteobacteria,1RPTV@1236|Gammaproteobacteria,1XHRV@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_9193_2 1123393.KB891316_gene1744 8.51e-95 291.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,dCache_1 k141_14824_2 314345.SPV1_02492 1.02e-37 140.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria 1224|Proteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis phnN GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_19685_1 1123247.AUIJ01000004_gene998 3.16e-45 157.0 2A3T9@1|root,30SB5@2|Bacteria,1RFGH@1224|Proteobacteria,2USHN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12713_1 1112217.PPL19_09887 7.94e-32 134.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria 1224|Proteobacteria M Phosphoglycerol transferase and related proteins alkaline phosphatase superfamily - - - - - - - - - - - - Sulfatase k141_18994_1 317025.Tcr_1779 5.34e-55 189.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,460F3@72273|Thiotrichales 72273|Thiotrichales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23 k141_18994_2 765913.ThidrDRAFT_2299 2.15e-16 78.6 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_21133_1 1288826.MSNKSG1_14412 6.18e-64 201.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_21133_2 1288826.MSNKSG1_14417 3.57e-190 527.0 COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,1T1TZ@1236|Gammaproteobacteria,46CYY@72275|Alteromonadaceae 1236|Gammaproteobacteria H Enoyl-CoA hydratase/isomerase menB - - ko:K07536 ko00362,ko01120,ko01220,map00362,map01120,map01220 M00540 R05592 RC01429 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_16892_1 1123360.thalar_01427 3.58e-121 360.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_143_1 1500893.JQNB01000001_gene593 1.11e-70 220.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1X38I@135614|Xanthomonadales 135614|Xanthomonadales V Transport permease protein yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_5018_1 1384054.N790_08090 6.8e-21 87.4 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,1X6WV@135614|Xanthomonadales 135614|Xanthomonadales M cell shape determination - - - - - - - - - - - - Bactofilin k141_5018_2 1163409.UUA_12308 3.41e-38 130.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1X6E5@135614|Xanthomonadales 135614|Xanthomonadales C Iron-sulfur cluster insertion protein ErpA erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_2961_1 1298593.TOL_0115 6.33e-71 224.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales 135619|Oceanospirillales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_1561_1 1278309.KB907104_gene823 7.45e-129 385.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XIYM@135619|Oceanospirillales 135619|Oceanospirillales M Rhs element Vgr protein - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_3664_1 1266998.ATUJ01000001_gene2608 3.11e-29 119.0 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria,2PVRV@265|Paracoccus 28211|Alphaproteobacteria T Sigma factor PP2C-like phosphatases - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HATPase_c_2,Response_reg,SpoIIE k141_16176_1 1294143.H681_05685 5.04e-70 226.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L belongs to the nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_14825_1 999547.KI421500_gene3700 2.37e-110 328.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,280EM@191028|Leisingera 28211|Alphaproteobacteria C Dehydrogenase E1 component acoA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,OxoDH_E1alpha_N k141_6432_1 870187.Thini_0101 1.34e-177 507.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,45ZX7@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_6432_2 768671.ThimaDRAFT_4194 6.29e-133 385.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1WWIU@135613|Chromatiales 135613|Chromatiales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_18995_1 519989.ECTPHS_01664 5.6e-31 120.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales 135613|Chromatiales T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_18995_2 1123261.AXDW01000007_gene2206 1.69e-13 68.6 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1XCMT@135614|Xanthomonadales 135614|Xanthomonadales GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_5019_1 1408473.JHXO01000008_gene2810 8.24e-32 125.0 COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - Beta-lactamase,Beta-lactamase2,DUF3471 k141_144_1 1255043.TVNIR_0858 1.22e-24 94.7 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1WY2D@135613|Chromatiales 135613|Chromatiales P TIGRFAM sulfur relay protein TusD DsrE dsrE GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_8526_1 1049564.TevJSym_aw00120 2.14e-139 414.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster dsrL - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,NADH_4Fe-4S,Pyr_redox_2 k141_8526_2 292415.Tbd_2476 7.22e-23 94.0 2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_12714_1 658612.MD26_13990 1.5e-30 114.0 COG0819@1|root,COG0819@2|Bacteria,1MVA0@1224|Proteobacteria,1RSHF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Long-chain fatty acid--CoA ligase - - - - - - - - - - - - Haem_oxygenas_2 k141_12714_2 1123487.KB892863_gene1914 8.21e-54 184.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VN53@28216|Betaproteobacteria,2KVZK@206389|Rhodocyclales 206389|Rhodocyclales I AMP-binding enzyme - - - - - - - - - - - - AMP-binding k141_7132_1 1278309.KB907103_gene1121 8.32e-129 369.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1XHD5@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_7132_2 1278309.KB907103_gene1122 2.52e-225 624.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RVJU@1236|Gammaproteobacteria,1XRIA@135619|Oceanospirillales 135619|Oceanospirillales I Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus - - - - - - - - - - - - Abhydrolase_1 k141_7132_3 1278309.KB907103_gene1123 4.48e-131 382.0 28KIX@1|root,2Z9Y0@2|Bacteria,1R427@1224|Proteobacteria,1RRGI@1236|Gammaproteobacteria,1XKH5@135619|Oceanospirillales 135619|Oceanospirillales S Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - - - - - - - - - - PHA_synth_III_E k141_7132_4 1278309.KB907103_gene1124 5.12e-166 469.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1XHP1@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_7132_5 1278309.KB907103_gene1125 1.47e-170 486.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XIQG@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_21751_1 102232.GLO73106DRAFT_00007690 9.55e-70 236.0 COG0745@1|root,COG3852@1|root,COG5001@1|root,COG0745@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_16893_1 1049564.TevJSym_bn00210 7.52e-10 62.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,1S21F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT k141_13423_3 314278.NB231_15178 3.19e-44 145.0 COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,1S9JX@1236|Gammaproteobacteria,1WZ5P@135613|Chromatiales 135613|Chromatiales CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL k141_5773_1 1123400.KB904746_gene1293 4.81e-08 59.7 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461P1@72273|Thiotrichales 72273|Thiotrichales F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C,Metallophos k141_5773_2 1288826.MSNKSG1_16631 7.49e-39 136.0 COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,1S1M7@1236|Gammaproteobacteria,468DW@72275|Alteromonadaceae 1236|Gammaproteobacteria K Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,GerE k141_18996_1 760568.Desku_0585 2.31e-50 176.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,263NB@186807|Peptococcaceae 186801|Clostridia G transporter, DctM subunit - - - ko:K21393 - - - - ko00000,ko02000 2.A.56.1 - - DctM,DctQ k141_21135_1 640081.Dsui_0760 0.00026 49.7 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,2KXST@206389|Rhodocyclales 206389|Rhodocyclales T Putative diguanylate phosphodiesterase - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - EAL,GGDEF,HAMP,PAS_8 k141_14826_2 1123073.KB899245_gene16 1.13e-17 82.8 COG3511@1|root,COG3511@2|Bacteria,1R78F@1224|Proteobacteria,1S2GR@1236|Gammaproteobacteria,1X929@135614|Xanthomonadales 135614|Xanthomonadales M Phosphoesterase family - - - - - - - - - - - - Phosphoesterase k141_5020_1 420662.Mpe_A0463 2.57e-15 75.9 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1KJRM@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_5020_2 713586.KB900536_gene1371 2.65e-56 184.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales 135613|Chromatiales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_8527_1 1354303.M917_0648 1.95e-17 85.9 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,3NM3J@468|Moraxellaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_8527_2 768671.ThimaDRAFT_2163 3.56e-14 68.2 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1WYT7@135613|Chromatiales 135613|Chromatiales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_7133_1 1278309.KB907101_gene808 1.43e-103 307.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XH8Q@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_13424_1 471874.PROSTU_03874 7.78e-68 216.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,3Z8AZ@586|Providencia 1236|Gammaproteobacteria H Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_7206_1 301.JNHE01000014_gene2990 9.64e-40 149.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YDB8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Cache 3/Cache 2 fusion domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_7206_2 1123518.ARWI01000001_gene1877 1.91e-81 248.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,460RW@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_7206_3 1209072.ALBT01000023_gene4048 2.18e-18 79.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1FHDQ@10|Cellvibrio 1236|Gammaproteobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808 FolB k141_4461_1 981327.F925_02631 2.44e-08 54.3 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,3NJHP@468|Moraxellaceae 1236|Gammaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_4461_2 290398.Csal_1631 9.04e-82 250.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XHKG@135619|Oceanospirillales 135619|Oceanospirillales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_4461_3 314278.NB231_01134 4.1e-87 267.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales 135613|Chromatiales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_20505_1 1042375.AFPL01000031_gene820 4.89e-84 261.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4646M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S11 family dacA GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664 PBP5_C,Peptidase_S11 k141_21865_1 1286106.MPL1_05177 5.29e-43 142.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,460VH@72273|Thiotrichales 72273|Thiotrichales O Peptidylprolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3 k141_7947_4 244582.JQAK01000007_gene2235 6.42e-20 82.8 COG0636@1|root,COG0636@2|Bacteria 2|Bacteria C ATP hydrolysis coupled proton transport atpE GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110,ko:K02124 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157,M00159 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1,3.A.2.2,3.A.2.3 - - ATP-synt_C k141_12117_1 391615.ABSJ01000042_gene2266 7.82e-47 164.0 COG2198@1|root,COG2198@2|Bacteria,1NFSM@1224|Proteobacteria,1SI4G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - Hpt k141_18378_1 1207063.P24_11180 8.13e-185 526.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2JQEC@204441|Rhodospirillales 204441|Rhodospirillales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_18378_2 187272.Mlg_2785 1.41e-137 411.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_18378_3 1121438.JNJA01000008_gene3906 3.13e-27 108.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2WITT@28221|Deltaproteobacteria,2M8DG@213115|Desulfovibrionales 28221|Deltaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_230_1 634956.Geoth_2449 2.66e-73 233.0 COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1WFX8@129337|Geobacillus 91061|Bacilli S Protein of unknown function (DUF1343) ybbC - - - - - - - - - - - DUF1343 k141_19748_1 864073.HFRIS_015940 9.61e-29 118.0 COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2VM9P@28216|Betaproteobacteria,472CK@75682|Oxalobacteraceae 28216|Betaproteobacteria T Member of a two-component regulatory system - - 2.7.13.3 ko:K07644 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HAMP,HATPase_c,HisKA k141_5104_2 305700.B447_19424 3.33e-122 367.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,2KVRC@206389|Rhodocyclales 206389|Rhodocyclales H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU k141_7237_2 1121396.KB893035_gene3578 1.15e-36 132.0 COG3637@1|root,COG3637@2|Bacteria,1N1ZM@1224|Proteobacteria,42U9G@68525|delta/epsilon subdivisions,2WSVE@28221|Deltaproteobacteria,2MMFF@213118|Desulfobacterales 28221|Deltaproteobacteria M Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL k141_8630_1 311402.Avi_0662 3.29e-56 181.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,4BE8C@82115|Rhizobiaceae 28211|Alphaproteobacteria L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_8630_2 936136.ARRT01000006_gene1913 4.05e-31 110.0 COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - YCII k141_7967_1 1120956.JHZK01000004_gene1434 2.13e-61 201.0 COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TRXS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_21226_1 745411.B3C1_10282 4.23e-19 83.6 COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria,1J5YK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 k141_21226_2 1278309.KB907099_gene2770 6.79e-71 233.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1XHJ4@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 k141_1681_1 192875.XP_004344501.1 1.77e-15 74.3 COG0237@1|root,KOG3220@2759|Eukaryota,38DFB@33154|Opisthokonta 33154|Opisthokonta H Dephospho-CoA kinase CAB5 GO:0000166,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005739,GO:0005783,GO:0005811,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990143 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE k141_1681_2 857087.Metme_0461 3.69e-46 156.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XDZI@135618|Methylococcales 135618|Methylococcales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_12815_1 316058.RPB_3596 9.37e-23 103.0 COG0784@1|root,COG3852@1|root,COG0784@2|Bacteria,COG3852@2|Bacteria,1NC9X@1224|Proteobacteria,2TXEG@28211|Alphaproteobacteria,3K6TV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg k141_18393_1 1049564.TevJSym_af00210 7.11e-55 184.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1J4NW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO k141_13500_1 713586.KB900536_gene602 1.26e-121 358.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1WW43@135613|Chromatiales 135613|Chromatiales J TIGRFAM Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_9289_2 754477.Q7C_787 6.17e-74 235.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales 72273|Thiotrichales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_17714_1 1033802.SSPSH_000672 5.88e-42 149.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_11439_1 395493.BegalDRAFT_2373 4.56e-06 54.3 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,460CJ@72273|Thiotrichales 72273|Thiotrichales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,TPR_1,TPR_2,VWA_2 k141_11439_2 1121918.ARWE01000001_gene2225 1.95e-23 101.0 COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria 1224|Proteobacteria S Oxygen tolerance batD - - - - - - - - - - - BatD k141_15605_2 500633.CLOHIR_00740 1.21e-18 90.1 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,25QHJ@186804|Peptostreptococcaceae 186801|Clostridia P PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_7968_1 1121875.KB907549_gene1707 5.65e-19 90.9 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 k141_8631_1 1123371.ATXH01000001_gene1207 2.1e-29 114.0 COG1216@1|root,COG1216@2|Bacteria,2GHKN@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_2320_1 1278309.KB907102_gene251 7.98e-96 301.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RPZD@1236|Gammaproteobacteria,1XHMC@135619|Oceanospirillales 135619|Oceanospirillales K Ribonuclease R winged-helix domain - - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_5841_1 1318628.MARLIPOL_03090 6.94e-181 513.0 COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,1RMI9@1236|Gammaproteobacteria,464FR@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases hutI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 k141_17715_2 396595.TK90_1768 5.89e-44 157.0 COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,LGT k141_11440_1 1198232.CYCME_0364 7.71e-75 241.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,45ZT8@72273|Thiotrichales 72273|Thiotrichales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_6487_2 999141.GME_18670 4.15e-103 313.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1XHSV@135619|Oceanospirillales 135619|Oceanospirillales O Cysteine desulfurase activator complex subunit SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 k141_10744_1 582744.Msip34_1878 8.89e-207 604.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,2KKQ5@206350|Nitrosomonadales 206350|Nitrosomonadales EF PFAM Carbamoyl-phosphate synthase L chain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_19769_1 187272.Mlg_1900 1.84e-148 437.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales 135613|Chromatiales O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_2321_1 525904.Tter_1969 1.82e-48 171.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_9972_1 207954.MED92_04147 2.25e-19 88.2 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XIW5@135619|Oceanospirillales 135619|Oceanospirillales NU Tfp pilus assembly protein - - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_9972_2 1278309.KB907103_gene1130 1.43e-177 499.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1XHYZ@135619|Oceanospirillales 135619|Oceanospirillales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_9972_3 1278309.KB907103_gene1131 1.24e-118 342.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1XJI9@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_9972_4 1278309.KB907103_gene1132 2.9e-99 298.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XHIG@135619|Oceanospirillales 135619|Oceanospirillales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_5842_1 754476.Q7A_1333 7.09e-61 195.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,460KG@72273|Thiotrichales 72273|Thiotrichales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_17716_1 314345.SPV1_09583 2.3e-64 219.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_3071_1 472759.Nhal_3609 5.2e-91 275.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_3071_2 443152.MDG893_00702 7.26e-22 92.4 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,4640R@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the ParA family fleN - - ko:K04562 - - - - ko00000,ko02035 - - - ParA k141_8632_1 870187.Thini_0172 1.61e-162 481.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_253_1 351348.Maqu_1932 1.7e-151 438.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,465BD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_253_2 1288826.MSNKSG1_08073 0.0 874.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,464YM@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_253_3 1288826.MSNKSG1_08068 4.83e-296 807.0 COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,46504@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 ko:K00347 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE k141_253_4 1288826.MSNKSG1_08063 4.23e-52 171.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,464V9@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind k141_7238_1 1278309.KB907101_gene652 0.0 882.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,1XHMD@135619|Oceanospirillales 135619|Oceanospirillales C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA - 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_5843_2 1123261.AXDW01000002_gene1651 0.000106 46.2 COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane protein domain - - - - - - - - - - - - DUF4339,RDD k141_17717_1 236097.ADG881_3315 7.3e-93 278.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,1XJ1T@135619|Oceanospirillales 135619|Oceanospirillales S ATPase, AAA - - - ko:K06923 - - - - ko00000 - - - DUF815 k141_21227_1 926549.KI421517_gene1758 4.22e-44 161.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia 976|Bacteroidetes H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_14199_1 1278309.KB907102_gene236 1.04e-129 389.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XHXE@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 k141_14199_2 1278309.KB907102_gene235 1.64e-122 356.0 296TZ@1|root,2ZU2Y@2|Bacteria,1RFP0@1224|Proteobacteria,1S4NC@1236|Gammaproteobacteria,1XKDS@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_21887_1 1288826.MSNKSG1_07943 1.4e-137 392.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,465QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_21887_2 1288826.MSNKSG1_07938 0.0 1557.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,464NY@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 PEP-utilizers,PEP-utilizers_C,PPDK_N k141_21887_3 1288826.MSNKSG1_07933 6.99e-112 321.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,466UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions rraA - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like k141_21887_4 1288826.MSNKSG1_07928 2.78e-62 191.0 2EPM2@1|root,33H7Q@2|Bacteria,1NH76@1224|Proteobacteria,1SGM6@1236|Gammaproteobacteria,468K8@72275|Alteromonadaceae 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_21887_5 270374.MELB17_08651 4.95e-36 128.0 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_3072_1 1049564.TevJSym_ao00790 2.19e-141 412.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1J4IG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_12816_1 870187.Thini_1967 6.14e-105 334.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales 72273|Thiotrichales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_20531_1 748224.HMPREF9436_00081 2.86e-30 117.0 2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia,3WJW5@541000|Ruminococcaceae 186801|Clostridia S non supervised orthologous group - - - - - - - - - - - - - k141_10745_1 713587.THITH_08275 7.76e-101 309.0 COG1075@1|root,COG1075@2|Bacteria,1MXMP@1224|Proteobacteria,1RYZM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - PGAP1 k141_10745_2 349521.HCH_03557 3.11e-33 119.0 2DDDK@1|root,2ZHMJ@2|Bacteria,1PB1M@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_9973_1 1249627.D779_1580 1.08e-09 60.1 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1WX5R@135613|Chromatiales 135613|Chromatiales I aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_9973_2 396588.Tgr7_2202 2.81e-67 219.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,1WXF3@135613|Chromatiales 135613|Chromatiales I Membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_17718_1 76869.PputGB1_0433 7.53e-84 257.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1YV5R@136845|Pseudomonas putida group 1236|Gammaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0056 PdxA k141_958_1 1288826.MSNKSG1_14657 2.37e-146 420.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,466CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_958_2 1288826.MSNKSG1_14652 5.58e-308 839.0 COG0661@1|root,COG0661@2|Bacteria,1N1UJ@1224|Proteobacteria,1RP1G@1236|Gammaproteobacteria,46AAZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S unusual protein kinase aarF - - - - - - - - - - - ABC1,APH k141_6489_1 349521.HCH_06351 1.09e-66 214.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XI42@135619|Oceanospirillales 135619|Oceanospirillales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_19770_1 400682.PAC_15711174 1.05e-109 336.0 COG1902@1|root,KOG0134@2759|Eukaryota,38UAR@33154|Opisthokonta,3BRHI@33208|Metazoa 33208|Metazoa C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN,Pyr_redox_2 k141_9290_1 305900.GV64_14330 4.16e-107 326.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XHVH@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein-ubiquinone oxidoreductase etf - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_3073_1 631362.Thi970DRAFT_02168 1.35e-48 171.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales 135613|Chromatiales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_19122_1 1278309.KB907106_gene1340 0.0 1275.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XHCH@135619|Oceanospirillales 135619|Oceanospirillales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_10746_1 377629.TERTU_1658 2.77e-81 253.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,1T0A1@1236|Gammaproteobacteria,2PQ2X@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S ImpA, N-terminal, type VI secretion system impA - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N k141_1809_2 398580.Dshi_0905 3.87e-57 184.0 COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6B7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - UPF0126 k141_15014_1 977880.RALTA_A2642 2.49e-59 199.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1K14Y@119060|Burkholderiaceae 28216|Betaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_15014_2 572477.Alvin_1089 2.61e-37 132.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1WWQJ@135613|Chromatiales 135613|Chromatiales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_10875_1 1167006.UWK_00550 6.93e-79 254.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions,2WK5W@28221|Deltaproteobacteria,2MIDT@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM Alpha amylase, catalytic treS - 2.4.1.4,2.4.1.7,3.2.1.1,5.4.99.16 ko:K00690,ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 - R00803,R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_18500_1 1232683.ADIMK_0166 4.43e-12 65.5 2BXMA@1|root,2ZBQ1@2|Bacteria,1MXZ1@1224|Proteobacteria,1SAQB@1236|Gammaproteobacteria,468C6@72275|Alteromonadaceae 1236|Gammaproteobacteria S (twin-arginine translocation) pathway signal - - - - - - - - - - - - Gluconate_2-dh3 k141_18500_2 1232683.ADIMK_0167 7.8e-65 209.0 COG0095@1|root,COG0095@2|Bacteria,1MZGC@1224|Proteobacteria,1RN92@1236|Gammaproteobacteria,46B78@72275|Alteromonadaceae 1236|Gammaproteobacteria H Lipoate-protein ligase - - - - - - - - - - - - - k141_17098_1 95619.PM1_0203500 7.38e-78 239.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K response regulator lrpR - - ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_17098_2 1207076.ALAT01000183_gene3016 2.04e-20 90.9 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1Z0VB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_7359_1 395493.BegalDRAFT_2469 5.56e-67 224.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_7359_2 187272.Mlg_2287 5.48e-88 271.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1WX82@135613|Chromatiales 135613|Chromatiales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_10140_2 1408445.JHXP01000002_gene1290 5.29e-37 131.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1JDHH@118969|Legionellales 118969|Legionellales U Biopolymer transport protein ExbD/TolR tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_15756_1 28229.ND2E_2563 7.28e-43 159.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,2Q5UC@267889|Colwelliaceae 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_8134_1 519989.ECTPHS_08343 1.98e-33 122.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1WYRU@135613|Chromatiales 135613|Chromatiales T PFAM Positive regulator of sigma(E), RseC MucC - - - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_8134_2 1122212.AULO01000008_gene1576 4.56e-107 325.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_19260_1 1121918.ARWE01000001_gene3368 2.23e-12 64.3 2EIAN@1|root,33C22@2|Bacteria,1NH5M@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_19260_2 1254432.SCE1572_24645 1.36e-68 244.0 COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43DX3@68525|delta/epsilon subdivisions,2X71G@28221|Deltaproteobacteria 28221|Deltaproteobacteria KLT AAA ATPase domain - - - - - - - - - - - - AAA_16,GAF,GAF_2,HATPase_c,HisKA_3,Pkinase,STAS k141_12272_1 553385.JEMF01000007_gene1805 2.06e-22 92.4 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,1XRFC@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1249) - - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_12272_2 582744.Msip34_2228 1.06e-22 97.4 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,2KNEN@206350|Nitrosomonadales 206350|Nitrosomonadales S Cobalt uptake substrate-specific transmembrane region - - - - - - - - - - - - CbiM k141_13640_2 1117647.M5M_16055 7.59e-73 228.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1J6XD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane lipoprotein-sorting protein VPA0557 - - - - - - - - - - - LolA_like k141_12972_1 1278309.KB907099_gene2649 2.78e-151 436.0 COG0644@1|root,COG0644@2|Bacteria,1R3YA@1224|Proteobacteria,1RSKZ@1236|Gammaproteobacteria,1XHXF@135619|Oceanospirillales 135619|Oceanospirillales C Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_12972_2 1298593.TOL_1469 1.95e-75 229.0 COG5113@1|root,COG3236@2|Bacteria,1RCXE@1224|Proteobacteria,1S8DV@1236|Gammaproteobacteria 1236|Gammaproteobacteria O protein conserved in bacteria - - - ko:K09935 - - - - ko00000 - - - DUF1768 k141_12972_3 1280001.BAOA01000022_gene643 8.3e-73 219.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1S5WM@1236|Gammaproteobacteria,1XXB5@135623|Vibrionales 135623|Vibrionales J translation initiation inhibitor, yjgF family - - - - - - - - - - - - Ribonuc_L-PSP k141_20634_1 1122137.AQXF01000004_gene1443 1.42e-38 134.0 COG3909@1|root,COG3909@2|Bacteria 2|Bacteria C cytochrome - - - - - - - - - - - - Cytochrom_C_2 k141_9399_1 317025.Tcr_1837 2.62e-65 208.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,45ZU9@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_9399_2 631362.Thi970DRAFT_03494 1.38e-44 153.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales 135613|Chromatiales S integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_9399_3 399739.Pmen_4153 7.6e-33 116.0 COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1YGP6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Belongs to the UPF0235 family yggU - - ko:K09131 - - - - ko00000 - - - DUF167 k141_9399_4 392500.Swoo_2418 6.17e-23 95.5 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5TB@1236|Gammaproteobacteria,2Q8W1@267890|Shewanellaceae 1236|Gammaproteobacteria S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_18501_1 1049564.TevJSym_aw00250 2.64e-06 48.9 2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM CRISPR-associated protein - - - - - - - - - - - - Cas6 k141_18501_2 1255043.TVNIR_0863 8.35e-20 81.3 2E3CD@1|root,32YBP@2|Bacteria,1N8PD@1224|Proteobacteria,1SCSK@1236|Gammaproteobacteria,1WZ7C@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_18501_3 396588.Tgr7_2184 2.28e-17 80.5 COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales 135613|Chromatiales Q Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD k141_5271_1 395019.Bmul_5359 9.96e-58 199.0 COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,2VHKW@28216|Betaproteobacteria,1JZRD@119060|Burkholderiaceae 28216|Betaproteobacteria T histidine kinase HAMP region domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_14290_1 1278309.KB907107_gene1644 2.85e-81 247.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1XJNK@135619|Oceanospirillales 135619|Oceanospirillales G Phosphoglycolate phosphatase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_14290_2 1278309.KB907107_gene1643 1.05e-164 464.0 COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XHJV@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03717 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_17832_2 1278309.KB907107_gene1671 3.34e-176 504.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XHPZ@135619|Oceanospirillales 135619|Oceanospirillales GM Polysaccharide biosynthesis protein wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_17099_1 1167006.UWK_00541 6.68e-26 105.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WJTJ@28221|Deltaproteobacteria,2MIYA@213118|Desulfobacterales 28221|Deltaproteobacteria M MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_17099_2 177437.HRM2_39210 5.64e-62 198.0 COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,42PWK@68525|delta/epsilon subdivisions,2WKW1@28221|Deltaproteobacteria,2MI9E@213118|Desulfobacterales 28221|Deltaproteobacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_12273_2 1163409.UUA_16623 2.34e-50 165.0 COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1X75A@135614|Xanthomonadales 135614|Xanthomonadales S Sulphur transport - - - - - - - - - - - - Sulf_transp k141_411_1 89187.ISM_07935 3.58e-76 233.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,46PDJ@74030|Roseovarius 28211|Alphaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_21334_2 1157708.KB907459_gene2108 7.32e-19 84.7 COG0702@1|root,COG0702@2|Bacteria,1PM6M@1224|Proteobacteria,2VMCW@28216|Betaproteobacteria 28216|Betaproteobacteria GM Nad-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase k141_18502_2 864702.OsccyDRAFT_4808 1.22e-34 122.0 COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1HB1V@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_9400_1 1122599.AUGR01000002_gene3375 2.2e-67 221.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1XHIS@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_17833_1 388399.SSE37_03285 7.44e-131 376.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria 28211|Alphaproteobacteria H COG2998 ABC-type tungstate transport system, permease component tupA - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 k141_1810_1 207954.MED92_14433 4.64e-61 211.0 COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XIGR@135619|Oceanospirillales 135619|Oceanospirillales I Acyltransferase - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,MFS_1 k141_1810_2 1278309.KB907101_gene316 3.06e-109 319.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1XH28@135619|Oceanospirillales 135619|Oceanospirillales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_5945_1 754476.Q7A_16 1.43e-51 185.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,45ZPD@72273|Thiotrichales 72273|Thiotrichales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_5945_2 765914.ThisiDRAFT_0356 3.47e-97 290.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1WW7W@135613|Chromatiales 135613|Chromatiales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_6626_2 314345.SPV1_13202 8.72e-83 260.0 COG0531@1|root,COG0531@2|Bacteria,1QXK2@1224|Proteobacteria 1224|Proteobacteria E amino acid - - - ko:K07076 - - - - ko00000 - - - AA_permease_2 k141_5272_1 498211.CJA_1910 1.66e-17 83.2 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1FFUQ@10|Cellvibrio 1236|Gammaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_5272_2 1211112.ALJC01000106_gene2668 2.6e-94 300.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_412_1 1121374.KB891585_gene2218 2.59e-20 86.7 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_412_2 998674.ATTE01000001_gene1100 2.01e-68 215.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,45ZX8@72273|Thiotrichales 72273|Thiotrichales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA k141_22014_1 1402135.SUH3_10420 1.86e-57 187.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2TS11@28211|Alphaproteobacteria,3ZVD5@60136|Sulfitobacter 28211|Alphaproteobacteria S Belongs to the UPF0246 family - - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_16391_1 1288826.MSNKSG1_15581 2.15e-204 583.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_16391_2 1288826.MSNKSG1_15586 8.69e-176 493.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RZ9D@1236|Gammaproteobacteria,469RA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Radical SAM - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM k141_2490_1 1288826.MSNKSG1_04236 3.87e-115 357.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0474 Cation transport ATPase - - 3.6.3.6 ko:K01535,ko:K12955 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.24,3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_9412_1 1278309.KB907109_gene3237 0.0 1117.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XH9T@135619|Oceanospirillales 135619|Oceanospirillales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_9412_2 1278309.KB907109_gene3236 0.0 871.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XHP7@135619|Oceanospirillales 135619|Oceanospirillales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_9412_3 1278309.KB907109_gene3235 1.35e-95 279.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XJNA@135619|Oceanospirillales 135619|Oceanospirillales S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_19903_2 1122201.AUAZ01000021_gene3215 8.49e-25 103.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,467Y0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_3871_1 1232683.ADIMK_1145 6.53e-87 265.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RPA8@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_20647_1 1121921.KB898707_gene1143 1.99e-79 241.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,2PNAS@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Ribosome recycling factor frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_429_1 1443665.JACA01000007_gene102 1.67e-67 217.0 COG0604@1|root,COG0604@2|Bacteria,4NJ5X@976|Bacteroidetes,1IIKA@117743|Flavobacteriia,2YHBR@290174|Aquimarina 976|Bacteroidetes C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_10900_1 999541.bgla_1g22390 3.73e-73 237.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria,1K2N3@119060|Burkholderiaceae 28216|Betaproteobacteria K PFAM sigma-54 factor interaction domain-containing protein - - - ko:K06714 - - - - ko00000,ko03000 - - - HTH_8,PAS_4,Sigma54_activat k141_4618_1 1278309.KB907100_gene1796 1.05e-223 640.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales 135619|Oceanospirillales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_15778_1 1122137.AQXF01000002_gene40 0.000518 42.4 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_8 k141_12992_1 318167.Sfri_0671 4.6e-70 221.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,2Q9CZ@267890|Shewanellaceae 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_18510_1 396588.Tgr7_3084 2.12e-94 281.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1RR9A@1236|Gammaproteobacteria,1WZVC@135613|Chromatiales 135613|Chromatiales S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_15035_1 1288826.MSNKSG1_05011 8.61e-120 350.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,464MT@72275|Alteromonadaceae 1236|Gammaproteobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 GcpE k141_15035_2 1288826.MSNKSG1_05006 1.62e-65 211.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,4689I@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria rodZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_430_1 1040989.AWZU01000004_gene6978 2.91e-43 149.0 COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2TV81@28211|Alphaproteobacteria,3JTQE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_8148_1 765910.MARPU_07805 5.39e-15 79.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXMA@135613|Chromatiales 135613|Chromatiales T Chemotaxis sensory transducer - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_8148_2 357804.Ping_3393 1.75e-90 281.0 COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,1T3FU@1236|Gammaproteobacteria 1236|Gammaproteobacteria T HD domain - - - - - - - - - - - - HD,HD_5 k141_20648_1 76114.ebA3623 4.67e-12 65.1 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2VHD1@28216|Betaproteobacteria,2KVBD@206389|Rhodocyclales 206389|Rhodocyclales C Alanine dehydrogenase/PNT, N-terminal domain - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_20648_2 590409.Dd586_1435 2.34e-19 84.0 COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,1S7S7@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_3240_1 425104.Ssed_3552 1.23e-110 335.0 COG0069@1|root,COG3369@1|root,COG0069@2|Bacteria,COG3369@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,2QA2N@267890|Shewanellaceae 1236|Gammaproteobacteria E Belongs to the glutamate synthase family gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Glu_synthase,Rieske,zf-CDGSH k141_22135_2 519989.ECTPHS_10276 1.66e-90 282.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales 135613|Chromatiales H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_11669_1 1211579.PP4_48150 2.21e-11 65.1 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,1RYY7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nitrilase - - 3.5.5.7 ko:K01502 ko00643,ko01120,map00643,map01120 - R05358 RC01336 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_11669_2 1116472.MGMO_21c00020 1.41e-27 117.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,1XG0U@135618|Methylococcales 135618|Methylococcales S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235 k141_17243_2 398578.Daci_4092 1.7e-09 58.2 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2VXCX@28216|Betaproteobacteria,4AIH5@80864|Comamonadaceae 28216|Betaproteobacteria S HNH endonuclease - - - - - - - - - - - - AP2,HNH_3 k141_12436_1 90813.JQMT01000001_gene436 3.46e-51 173.0 COG0564@1|root,COG0564@2|Bacteria,1R4IN@1224|Proteobacteria,1S0WR@1236|Gammaproteobacteria,461ZJ@72273|Thiotrichales 72273|Thiotrichales J RNA pseudouridylate synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_4751_1 1191299.AJYX01000102_gene2580 7.9e-77 242.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales 135623|Vibrionales L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_18007_1 1278309.KB907108_gene1557 2.89e-137 392.0 293CN@1|root,2ZQV6@2|Bacteria,1RF4G@1224|Proteobacteria,1T0P6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18007_2 1278309.KB907108_gene1558 2.87e-231 640.0 COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria 1224|Proteobacteria S Ethylbenzene dehydrogenase - - - - - - - - - - - - EB_dh k141_18007_3 1122134.KB893650_gene1314 2.28e-164 469.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,1XHT2@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0176 family - - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_18007_4 1278309.KB907108_gene1563 3.54e-67 211.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XIGK@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_19996_1 1278309.KB907102_gene216 1.59e-115 342.0 COG2199@1|root,COG2199@2|Bacteria 2|Bacteria T diguanylate cyclase activity - - - - - - - - - - - - CHASE,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_19996_2 768671.ThimaDRAFT_0124 2.94e-09 58.5 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,1RMZV@1236|Gammaproteobacteria,1X2SU@135613|Chromatiales 135613|Chromatiales O OsmC-like protein - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_10286_1 1335757.SPICUR_07570 2.03e-57 187.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1WY99@135613|Chromatiales 135613|Chromatiales H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE k141_10286_2 930166.CD58_25285 9.88e-22 86.3 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - ko:K09862 - - - - ko00000 - - - YacG k141_10286_3 546266.NEIMUCOT_06297 2.37e-07 51.6 2BWYA@1|root,32WXT@2|Bacteria,1N26T@1224|Proteobacteria,2VU1E@28216|Betaproteobacteria,2KRKZ@206351|Neisseriales 206351|Neisseriales - - - - - - - - - - - - - - - k141_16544_1 1288826.MSNKSG1_18440 4.13e-190 539.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,4663F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - iECO103_1326.ECO103_1114 MVIN k141_16544_2 1288826.MSNKSG1_18435 1.56e-49 158.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,468SF@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_16544_3 1288826.MSNKSG1_18430 1.2e-259 712.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,464V7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_16544_4 153721.MYP_4656 2.09e-09 58.5 COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia 976|Bacteroidetes S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_13115_2 398580.Dshi_3499 4.35e-85 261.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG0500 SAM-dependent methyltransferases bioC - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_1268_1 351016.RAZWK3B_15063 1.08e-33 120.0 COG5502@1|root,COG5502@2|Bacteria,1NB8V@1224|Proteobacteria,2U9GZ@28211|Alphaproteobacteria,2P4YA@2433|Roseobacter 28211|Alphaproteobacteria S Uncharacterized conserved protein (DUF2267) - - - - - - - - - - - - DUF2267 k141_2596_1 713586.KB900536_gene134 8.59e-46 163.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales 135613|Chromatiales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_1282_4 574966.KB898648_gene778 4.54e-155 454.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,1RRRD@1236|Gammaproteobacteria,1XNA5@135619|Oceanospirillales 135619|Oceanospirillales EG Belongs to the IlvD Edd family - - 4.2.1.82 ko:K22186 ko00040,map00040 - R02429 RC00543 ko00000,ko00001,ko01000 - - - ILVD_EDD k141_2610_1 1120951.AUBG01000011_gene2285 9.43e-106 313.0 COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia 976|Bacteroidetes S Conserved protein domain typically associated with flavoprotein - - - - - - - - - - - - Flavin_Reduct k141_564_1 1278309.KB907099_gene2779 1.33e-274 756.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XHC5@135619|Oceanospirillales 135619|Oceanospirillales E alanine symporter dagA - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_564_2 1278309.KB907099_gene2780 3.99e-243 676.0 COG3048@1|root,COG3048@2|Bacteria,1MUJS@1224|Proteobacteria,1RNBW@1236|Gammaproteobacteria,1XH8X@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA - 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - - PALP k141_4775_1 765912.Thimo_3524 6.48e-20 89.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1X2FT@135613|Chromatiales 135613|Chromatiales S PFAM Aminoglycoside phosphotransferase - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_4775_2 768671.ThimaDRAFT_1127 9.07e-55 178.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales 135613|Chromatiales JM PFAM Nucleotidyl transferase - - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase k141_5461_1 349521.HCH_02597 1.59e-31 115.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1XKMI@135619|Oceanospirillales 135619|Oceanospirillales CO Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA,Redoxin k141_5461_2 1127673.GLIP_2933 6.63e-24 101.0 COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,46D8K@72275|Alteromonadaceae 1236|Gammaproteobacteria I Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_13837_1 472759.Nhal_2242 1.29e-72 233.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_22160_1 743721.Psesu_0674 2.01e-28 120.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1X3CZ@135614|Xanthomonadales 135614|Xanthomonadales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_13140_1 1479237.JMLY01000001_gene1648 2.14e-08 62.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria,469SM@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - MerC,Methyltransf_31 k141_2611_1 633131.TR2A62_1847 8.02e-118 348.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_20728_1 1288826.MSNKSG1_15991 9.51e-81 244.0 COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,1RXZH@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_20728_2 1288826.MSNKSG1_15986 5.48e-265 726.0 COG0683@1|root,COG0683@2|Bacteria,1P7P3@1224|Proteobacteria,1RY95@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_6749_1 198628.Dda3937_03389 1.27e-69 219.0 COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,2JCEV@204037|Dickeya 1236|Gammaproteobacteria L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair mutH GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - ko:K03573 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutH k141_17265_1 1278309.KB907101_gene585 3.24e-126 368.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XI78@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_17265_2 1278309.KB907101_gene584 5.91e-100 292.0 COG1683@1|root,COG1683@2|Bacteria,1RHER@1224|Proteobacteria,1S6AV@1236|Gammaproteobacteria,1XJZ7@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF523) - - - - - - - - - - - - DUF523 k141_17265_3 1278309.KB907101_gene583 1.93e-163 461.0 COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1RPXU@1236|Gammaproteobacteria 1236|Gammaproteobacteria M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_19388_2 1117647.M5M_13880 9.85e-61 194.0 2EP53@1|root,33GRT@2|Bacteria,1NZ06@1224|Proteobacteria,1SQ7M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19388_5 443152.MDG893_05364 1.65e-77 231.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,467F9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_22161_1 1278309.KB907099_gene2607 6.01e-27 105.0 COG0583@1|root,COG0583@2|Bacteria,1MVGZ@1224|Proteobacteria,1RRFH@1236|Gammaproteobacteria,1XK20@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_6094_1 1278309.KB907111_gene3363 1.54e-90 290.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XH4C@135619|Oceanospirillales 135619|Oceanospirillales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_6094_2 1278309.KB907111_gene3362 2.82e-211 585.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1XH75@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_6094_3 1278309.KB907111_gene3361 3.35e-138 394.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1XH86@135619|Oceanospirillales 135619|Oceanospirillales O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans k141_6094_4 1278309.KB907111_gene3360 2.47e-160 450.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1XJ6T@135619|Oceanospirillales 135619|Oceanospirillales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate - 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_6094_6 1278309.KB907111_gene3358 7.14e-211 602.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XHDW@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_565_1 875328.JDM601_2518 2.01e-39 142.0 COG1322@1|root,COG1322@2|Bacteria,2HSI0@201174|Actinobacteria,23C8J@1762|Mycobacteriaceae 201174|Actinobacteria S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC k141_565_2 1217720.ALOX01000040_gene2943 2.7e-32 117.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,2JPKI@204441|Rhodospirillales 204441|Rhodospirillales H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_8272_1 381666.H16_B0377 1.21e-54 191.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJVN@28216|Betaproteobacteria,1K4H7@119060|Burkholderiaceae 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Response_reg k141_8272_2 1380380.JIAX01000006_gene1030 8.14e-07 51.2 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator ttdR - - - - - - - - - - - HTH_1,LysR_substrate k141_11032_1 1288826.MSNKSG1_18130 8.12e-104 306.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,466K6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_11032_2 1288826.MSNKSG1_18125 0.0 1016.0 COG0463@1|root,COG3307@1|root,COG0463@2|Bacteria,COG3307@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,466FF@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 2 kdtX - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 k141_11032_3 1288826.MSNKSG1_18120 1.28e-252 694.0 COG1887@1|root,COG1887@2|Bacteria,1R4G5@1224|Proteobacteria,1RNVW@1236|Gammaproteobacteria,464RF@72275|Alteromonadaceae 1236|Gammaproteobacteria M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC XAC3795 - - - - - - - - - - - Epimerase_2,Glyphos_transf k141_11032_4 1288826.MSNKSG1_18115 4.78e-270 739.0 COG0438@1|root,COG0438@2|Bacteria,1PDW1@1224|Proteobacteria,1RZIK@1236|Gammaproteobacteria,469U7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_11032_5 1288826.MSNKSG1_18110 2.17e-159 448.0 COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,466MU@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo k141_11032_6 1288826.MSNKSG1_18105 3.1e-245 674.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,465RD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0859 ADP-heptose LPS heptosyltransferase opsX - - ko:K12982 - - - - ko00000,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_11032_7 1288826.MSNKSG1_18100 6.6e-310 847.0 COG3307@1|root,COG3307@2|Bacteria,1RBUE@1224|Proteobacteria,1S3G3@1236|Gammaproteobacteria 1236|Gammaproteobacteria M O-Antigen ligase - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C k141_11032_8 1288826.MSNKSG1_18095 1.1e-225 621.0 COG1442@1|root,COG1442@2|Bacteria,1N9H7@1224|Proteobacteria,1RQGY@1236|Gammaproteobacteria,469A6@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1442 Lipopolysaccharide biosynthesis proteins, LPS glycosyltransferases rfaI GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0047270,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.44,2.4.1.58 ko:K03275,ko:K03276,ko:K03278,ko:K03279 ko00540,ko01100,map00540,map01100 M00080 R01994,R01997 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT8 - Glyco_transf_8,Glyco_transf_8C k141_11032_9 1288826.MSNKSG1_18090 6.43e-237 651.0 COG1442@1|root,COG1442@2|Bacteria,1N9H7@1224|Proteobacteria,1RQGY@1236|Gammaproteobacteria,469A6@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1442 Lipopolysaccharide biosynthesis proteins, LPS glycosyltransferases rfaI GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0047270,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.44,2.4.1.58 ko:K03275,ko:K03276,ko:K03278,ko:K03279 ko00540,ko01100,map00540,map01100 M00080 R01994,R01997 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT8 - Glyco_transf_8,Glyco_transf_8C k141_11032_10 1288826.MSNKSG1_18085 1.47e-84 250.0 COG0859@1|root,COG0859@2|Bacteria,1MZGQ@1224|Proteobacteria,1S7TT@1236|Gammaproteobacteria,46AYD@72275|Alteromonadaceae 1236|Gammaproteobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - - k141_11032_11 1288826.MSNKSG1_18080 4.45e-224 617.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,465RB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 Aminotran_4 k141_11032_12 1288826.MSNKSG1_18075 2.06e-145 435.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_18679_1 83219.PM02_02630 3.03e-125 369.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,3ZWXM@60136|Sulfitobacter 28211|Alphaproteobacteria C 4Fe-4S dicluster domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_4776_2 637905.SVI_0358 1.02e-06 52.4 2EICS@1|root,33C43@2|Bacteria,1NIAI@1224|Proteobacteria,1SGPY@1236|Gammaproteobacteria,2QCPZ@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14422_1 43989.cce_0220 1.04e-27 125.0 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G1ZJ@1117|Cyanobacteria,3KGN8@43988|Cyanothece 1117|Cyanobacteria T histidine kinase A domain protein - - - - - - - - - - - - CBS,HATPase_c,HisKA,Response_reg k141_13838_1 1158165.KB898872_gene1027 7.04e-42 155.0 COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,LGT k141_566_1 1121859.KB890739_gene2339 2.69e-63 219.0 COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,47YNN@768503|Cytophagia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k141_15906_1 1288826.MSNKSG1_12502 2.24e-98 298.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464I1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0417 Anth_synt_I_N,Chorismate_bind k141_15906_2 1288826.MSNKSG1_12497 6.65e-166 463.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,466TE@72275|Alteromonadaceae 1236|Gammaproteobacteria G haloacid dehalogenase-like hydrolase gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 HAD_2 k141_15906_3 1288826.MSNKSG1_12492 1.02e-159 447.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,465KW@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0155,iYL1228.KPN_03757 Ribul_P_3_epim k141_15906_4 1288826.MSNKSG1_12487 4.67e-101 300.0 28P7Z@1|root,2ZC25@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3530) - - - - - - - - - - - - DUF3530 k141_3982_1 1278309.KB907102_gene165 5.33e-300 840.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1XH65@135619|Oceanospirillales 135619|Oceanospirillales L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,Flavi_DEAD,HA2,Helicase_C,HrpB_C k141_10309_1 1288826.MSNKSG1_05211 9.27e-127 369.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,4673V@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_10309_2 1288826.MSNKSG1_05216 0.0 1287.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_10309_3 1288826.MSNKSG1_05221 0.0 1775.0 COG1520@1|root,COG1520@2|Bacteria,1QXFQ@1224|Proteobacteria,1SPEA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - k141_10309_4 1288826.MSNKSG1_05226 9.78e-141 398.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity - - - - - - - - - - - - CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg k141_10309_5 1288826.MSNKSG1_05231 1.5e-234 659.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_5462_1 1232410.KI421421_gene3650 2.76e-179 517.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WTUB@28221|Deltaproteobacteria,43T1I@69541|Desulfuromonadales 28221|Deltaproteobacteria NU General secretory system II, protein E domain protein pulE-1 - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_12457_1 396588.Tgr7_0832 8.58e-159 465.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1WWHQ@135613|Chromatiales 135613|Chromatiales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_12457_2 754477.Q7C_679 7.87e-58 182.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,46112@72273|Thiotrichales 72273|Thiotrichales H queuosine biosynthesis protein QueD - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_12457_3 396588.Tgr7_0830 8.96e-120 347.0 COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1WW3H@135613|Chromatiales 135613|Chromatiales S Converts GTP to 7,8-dihydroneopterin triphosphate folE2 - 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GCHY-1 k141_2612_1 1288826.MSNKSG1_01903 1.3e-276 763.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RNHN@1236|Gammaproteobacteria,469NB@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acs-2 - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_8855_3 349102.Rsph17025_0477 1.29e-06 52.4 COG0582@1|root,COG0582@2|Bacteria,1R3TM@1224|Proteobacteria,2TS94@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_2799_2 1122134.KB893651_gene1782 1.32e-51 165.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1XK4T@135619|Oceanospirillales 135619|Oceanospirillales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_2799_3 697282.Mettu_1329 1.96e-48 155.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1XFEB@135618|Methylococcales 135618|Methylococcales J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS - - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_18137_2 644107.SL1157_1394 7.86e-65 202.0 COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2UG0P@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_18137_3 391616.OA238_c01780 1.29e-46 167.0 COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria 28211|Alphaproteobacteria H COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases cobN - 6.6.1.2 ko:K02230 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobN-Mg_chel k141_15359_2 765910.MARPU_15680 3.36e-186 530.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales 135613|Chromatiales C PFAM malic - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_726_1 1168067.JAGP01000001_gene1061 2.14e-33 125.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,460TE@72273|Thiotrichales 72273|Thiotrichales D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA k141_13963_1 225937.HP15_2374 9.36e-68 225.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RQMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria H FOG TPR repeat - - - - - - - - - - - - Methyltransf_25,Methyltransf_31,TPR_1,TPR_11,TPR_12,TPR_16,TPR_8 k141_11874_1 472759.Nhal_2571 6.7e-117 351.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,1WW06@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_6994_1 395493.BegalDRAFT_1796 1.01e-98 302.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales 72273|Thiotrichales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_18845_1 317025.Tcr_1800 2.17e-78 242.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_20933_1 1278309.KB907106_gene1356 3.73e-215 599.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XI4K@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_20933_2 1278309.KB907106_gene1355 8.58e-237 656.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1XI2X@135619|Oceanospirillales 135619|Oceanospirillales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obgE - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_16755_2 535289.Dtpsy_1062 1.68e-29 110.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria,4AEPV@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Cytochrome c, class I nosC - - - - - - - - - - - Cytochrome_CBB3 k141_10470_1 232721.Ajs_0553 9.44e-31 120.0 COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,2VSU8@28216|Betaproteobacteria,4AF2F@80864|Comamonadaceae 28216|Betaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_10470_2 396588.Tgr7_1990 6.89e-78 269.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg k141_14666_1 261292.Nit79A3_3538 5.67e-31 118.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,3725K@32003|Nitrosomonadales 28216|Betaproteobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_14666_2 76869.PputGB1_4510 2.11e-104 313.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1YWD8@136845|Pseudomonas putida group 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_11179_1 1121904.ARBP01000007_gene3050 8.21e-55 189.0 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_2112_1 1298593.TOL_2459 3.4e-31 122.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XKAP@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_8389_1 247633.GP2143_00647 3.54e-30 115.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1J5WU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_8389_2 472759.Nhal_3851 1.3e-10 61.6 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales 135613|Chromatiales D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD - - ko:K18778 - - - - ko00000,ko03036 - - - ZapD k141_19545_2 1415754.JQMK01000012_gene952 1.8e-156 447.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,464HM@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase k141_3505_1 1288826.MSNKSG1_17256 4.81e-154 444.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_1414_1 366394.Smed_5899 8.45e-79 250.0 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2TU5N@28211|Alphaproteobacteria,4BCDA@82115|Rhizobiaceae 28211|Alphaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_727_1 1190606.AJYG01000139_gene44 2.7e-15 74.7 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XUGG@135623|Vibrionales 135623|Vibrionales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH-1 - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_727_2 1286106.MPL1_10747 4.38e-71 228.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,4606G@72273|Thiotrichales 72273|Thiotrichales O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_20934_1 1298880.AUEV01000002_gene1365 1.12e-80 253.0 COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria 201174|Actinobacteria CH 4-hydroxybenzoate 3-monooxygenase - - 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R01298 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3 k141_18138_1 545276.KB898724_gene1763 5.79e-34 130.0 COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_18138_2 251221.35210744 1.11e-24 94.4 2E3CN@1|root,32YBX@2|Bacteria,1G8Z2@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_18_1 1217648.F933_01489 0.000429 47.8 28IZ5@1|root,2Z8WP@2|Bacteria,1R6WI@1224|Proteobacteria,1S87I@1236|Gammaproteobacteria,3NM14@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4200_1 288000.BBta_2766 2.52e-151 450.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JSW3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MA20_17495 - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_11875_1 768671.ThimaDRAFT_0289 2.81e-40 149.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_16756_1 1122194.AUHU01000003_gene2293 4.18e-29 115.0 COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,1T0A1@1236|Gammaproteobacteria,466QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S ImpA, N-terminal, type VI secretion system impA - - ko:K11902 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - ImpA_N k141_16756_2 1122194.AUHU01000003_gene2292 6.39e-45 149.0 COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,1T190@1236|Gammaproteobacteria,466ZG@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type VI secretion system, VipA, VC_A0107 or Hcp2 impB - - ko:K11901 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA k141_11180_2 1123368.AUIS01000003_gene1581 1.9e-14 74.7 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,2NC36@225057|Acidithiobacillales 225057|Acidithiobacillales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_10471_1 1116472.MGMO_60c00060 6.31e-67 214.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XDMP@135618|Methylococcales 135618|Methylococcales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_14667_1 1122201.AUAZ01000001_gene2405 3.73e-128 382.0 COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,1RNYN@1236|Gammaproteobacteria,469TH@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase - - 1.3.99.4 ko:K05898 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R09884 RC00991 ko00000,ko00001,ko01000 - - - FAD_binding_2 k141_728_1 1069080.KB913028_gene373 4.32e-49 164.0 COG4123@1|root,COG4123@2|Bacteria 2|Bacteria AJ Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k141_17438_2 1288826.MSNKSG1_10843 0.0 921.0 COG1350@1|root,COG1350@2|Bacteria,1QXG0@1224|Proteobacteria,1T3B3@1236|Gammaproteobacteria,46D4P@72275|Alteromonadaceae 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_17438_3 1288826.MSNKSG1_10838 0.0 1072.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,464DM@72275|Alteromonadaceae 1236|Gammaproteobacteria S SpoVR family ycgB GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - ko:K06415 - - - - ko00000 - - - SpoVR k141_17438_4 1288826.MSNKSG1_10833 1.35e-71 226.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,464ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_9776_1 1411685.U062_01503 0.000138 46.6 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1J4DG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N flagellar hook-associated protein flgK GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0044085,GO:0044780,GO:0044781,GO:0070925,GO:0071840 - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_9776_2 1278309.KB907107_gene1744 1.72e-190 537.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1XI0F@135619|Oceanospirillales 135619|Oceanospirillales MNOU Rod binding protein flgJ - - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k141_9776_3 1278309.KB907107_gene1745 7.47e-188 528.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XIS3@135619|Oceanospirillales 135619|Oceanospirillales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_19546_2 176299.Atu3280 7.04e-39 136.0 COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2TV81@28211|Alphaproteobacteria,4BCNY@82115|Rhizobiaceae 28211|Alphaproteobacteria K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA k141_20240_1 1288826.MSNKSG1_01028 4.35e-188 538.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_20240_2 1288826.MSNKSG1_01033 1.12e-308 850.0 COG2936@1|root,COG2936@2|Bacteria,1R4GM@1224|Proteobacteria,1RRE7@1236|Gammaproteobacteria,46AX5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase S15 - - - - - - - - - - - - Peptidase_S15 k141_9079_1 472759.Nhal_2780 7.34e-121 353.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RWHU@1236|Gammaproteobacteria,1WYF3@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161,ko:K00162,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_1415_1 870187.Thini_1819 1.36e-80 255.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,4628N@72273|Thiotrichales 72273|Thiotrichales S Sulphur transport - - - - - - - - - - - - Sulf_transp k141_13272_1 1288826.MSNKSG1_16201 4.05e-155 455.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,465UH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - - - - - - - - - - AMP-binding,Haem_oxygenas_2 k141_13272_2 1288826.MSNKSG1_16196 7.66e-159 446.0 2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,1S8Z8@1236|Gammaproteobacteria,468BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thermostable hemolysin - - - - - - - - - - - - T_hemolysin k141_13272_3 1288826.MSNKSG1_16191 4.36e-92 269.0 COG2246@1|root,COG2246@2|Bacteria,1N8AB@1224|Proteobacteria,1SEJX@1236|Gammaproteobacteria,4694T@72275|Alteromonadaceae 1236|Gammaproteobacteria S GtrA-like protein - - - - - - - - - - - - GtrA k141_13272_4 1288826.MSNKSG1_16186 3.72e-20 87.4 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,464H5@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis gtrB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 k141_4899_1 522306.CAP2UW1_2118 2.11e-95 324.0 COG1352@1|root,COG2201@1|root,COG3829@1|root,COG5001@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9 k141_3506_1 1094715.CM001373_gene426 8.01e-05 44.3 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1JCJK@118969|Legionellales 118969|Legionellales L Belongs to the DnaA family. HdA subfamily hda - - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_3506_2 1026882.MAMP_02913 4.1e-25 99.4 COG3308@1|root,COG3308@2|Bacteria,1N5UB@1224|Proteobacteria,1SAAJ@1236|Gammaproteobacteria,4634G@72273|Thiotrichales 72273|Thiotrichales S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_3506_3 765913.ThidrDRAFT_1438 1.69e-57 184.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales 135613|Chromatiales S Belongs to the WrbA family - - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_6289_1 1278309.KB907100_gene2139 8e-168 483.0 COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,1RNSS@1236|Gammaproteobacteria,1XH87@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) astB - 3.5.3.23 ko:K01484 ko00330,ko01100,map00330,map01100 - R04189 RC00024 ko00000,ko00001,ko01000 - - - AstB k141_6289_2 1278309.KB907100_gene2140 0.0 1422.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_9 k141_6289_3 1278309.KB907100_gene2141 4.05e-158 454.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNG1@1236|Gammaproteobacteria,1XR30@135619|Oceanospirillales 135619|Oceanospirillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_17439_1 1209072.ALBT01000033_gene1519 5.65e-40 141.0 COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,1S3KC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - MarR_2,NTP_transf_2 k141_6998_1 351016.RAZWK3B_05437 1e-57 181.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,2P36B@2433|Roseobacter 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_9792_1 2340.JV46_06570 2.24e-120 369.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_11883_2 1288826.MSNKSG1_17728 0.0 2595.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,464QF@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_11883_3 1288826.MSNKSG1_17723 1.61e-61 191.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,46787@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_11883_4 1288826.MSNKSG1_17718 2.69e-114 328.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,46765@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_11883_5 1288826.MSNKSG1_17713 2.66e-153 432.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,4649G@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_11883_6 1288826.MSNKSG1_17708 1.49e-95 278.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,466G4@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N k141_11883_7 1288826.MSNKSG1_17703 7.48e-126 358.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,4644G@72275|Alteromonadaceae 1236|Gammaproteobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_11883_8 1288826.MSNKSG1_17698 3.35e-73 220.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,467U5@72275|Alteromonadaceae 1236|Gammaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_11883_9 69042.WH5701_01035 1.58e-06 52.0 2CHP8@1|root,2ZAVY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_19556_1 1278309.KB907102_gene30 1.92e-107 333.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XI0P@135619|Oceanospirillales 135619|Oceanospirillales D protein involved in exopolysaccharide biosynthesis - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz k141_3519_1 767434.Fraau_0599 4.25e-45 160.0 COG0454@1|root,COG1947@1|root,COG0454@2|Bacteria,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1X30B@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,GHMP_kinases_C,GHMP_kinases_N k141_10488_1 458817.Shal_2037 2.32e-12 67.4 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,2QBU8@267890|Shewanellaceae 1236|Gammaproteobacteria S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant gph GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006040,GO:0006082,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009254,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0030203,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097172,GO:1901135,GO:1901360,GO:1901564 3.1.3.105,3.1.3.18 ko:K01091,ko:K22292 ko00520,ko00630,ko01100,ko01110,ko01130,map00520,map00630,map01100,map01110,map01130 - R01334,R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_10488_2 1396858.Q666_12475 1.14e-36 130.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k141_11205_1 1121937.AUHJ01000002_gene3434 1.45e-57 186.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,46AVD@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_11205_2 1123518.ARWI01000001_gene538 4.12e-52 171.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1S357@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B k141_13977_1 1328313.DS2_07988 3.21e-09 56.6 2E92A@1|root,333BE@2|Bacteria,1N8BM@1224|Proteobacteria,1SDV1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13977_4 1278309.KB907110_gene3168 1.28e-274 752.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,1RMRY@1236|Gammaproteobacteria,1XIED@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE k141_13977_5 1278309.KB907110_gene3167 1.45e-91 273.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,1RQ62@1236|Gammaproteobacteria,1XHFI@135619|Oceanospirillales 135619|Oceanospirillales S ATPase, AAA - - - - - - - - - - - - AAA,AAA_5 k141_9102_1 1123053.AUDG01000026_gene175 1.61e-43 153.0 COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria J protein conserved in bacteria cvfB - - ko:K00243 - - - - ko00000 - - - S1_2 k141_15379_1 1041147.AUFB01000005_gene2649 1.1e-207 587.0 COG3488@1|root,COG3488@2|Bacteria,1Q801@1224|Proteobacteria,2U3GU@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Di-haem oxidoreductase, putative peroxidase - - - - - - - - - - - - DHOR k141_14686_1 1166018.FAES_0318 3.31e-30 123.0 COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,47JI0@768503|Cytophagia 976|Bacteroidetes D DNA segregation ATPase FtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_12591_1 765910.MARPU_15680 1.35e-130 383.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales 135613|Chromatiales C PFAM malic - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_8401_1 1121921.KB898707_gene1285 4.35e-19 90.1 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,2PP4I@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria G Aldose 1-epimerase yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_5734_2 1219031.BBJR01000048_gene1744 3.89e-26 100.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,4ADW0@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 k141_1518_1 472759.Nhal_1969 4.42e-16 77.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales 135613|Chromatiales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_1518_2 1207076.ALAT01000147_gene415 4.9e-86 259.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1Z2BU@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_9171_1 90813.JQMT01000001_gene86 2.58e-31 115.0 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,4628I@72273|Thiotrichales 72273|Thiotrichales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_9171_2 1469245.JFBG01000001_gene536 2.32e-12 70.5 COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,1WXQ5@135613|Chromatiales 135613|Chromatiales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_8497_2 314278.NB231_10778 1.74e-78 239.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_16863_1 887898.HMPREF0551_0439 8.09e-161 459.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,1K1ES@119060|Burkholderiaceae 28216|Betaproteobacteria E PFAM aminotransferase class I and II alaA - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_19645_1 314345.SPV1_13177 1.77e-64 209.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel ynaI - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_14079_1 1530186.JQEY01000020_gene591 2.23e-105 316.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_15505_1 216591.BCAS0274 4.18e-30 116.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VMK8@28216|Betaproteobacteria,1K21W@119060|Burkholderiaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_21712_1 935261.JAGL01000009_gene1180 1.53e-38 138.0 2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,2UI0N@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_3628_1 1298593.TOL_1109 1.77e-127 394.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XI50@135619|Oceanospirillales 135619|Oceanospirillales S exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_12678_1 998674.ATTE01000001_gene213 2.38e-40 138.0 COG0393@1|root,COG0393@2|Bacteria,1N6BK@1224|Proteobacteria,1SAFJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 k141_12678_2 998674.ATTE01000001_gene214 2.92e-68 219.0 COG0501@1|root,COG0501@2|Bacteria,1R0V5@1224|Proteobacteria,1SBIF@1236|Gammaproteobacteria 1236|Gammaproteobacteria O peptidase M48, Ste24p - - - - - - - - - - - - Peptidase_M48 k141_4983_2 90813.JQMT01000001_gene1942 5.1e-39 137.0 COG3216@1|root,COG3216@2|Bacteria,1N1Q6@1224|Proteobacteria,1S9HF@1236|Gammaproteobacteria,462DH@72273|Thiotrichales 72273|Thiotrichales S Uncharacterized protein conserved in bacteria (DUF2062) - - - - - - - - - - - - DUF2062 k141_2922_1 935848.JAEN01000007_gene2947 4.02e-54 176.0 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2U9G4@28211|Alphaproteobacteria,2PWSK@265|Paracoccus 28211|Alphaproteobacteria P Ferric uptake regulator family - - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR k141_2922_2 391616.OA238_c10010 6.17e-30 114.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC - - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC_tran k141_21104_1 377629.TERTU_1108 3.75e-09 61.6 COG4967@1|root,COG4967@2|Bacteria,1PCTA@1224|Proteobacteria,1SXXF@1236|Gammaproteobacteria,2PQ6B@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NU type IV pilus modification protein PilV - - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - - k141_4318_1 1163409.UUA_07193 7.55e-106 310.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1X4NJ@135614|Xanthomonadales 135614|Xanthomonadales J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_13388_1 879212.DespoDRAFT_00201 9.09e-20 98.6 COG0642@1|root,COG0745@1|root,COG2984@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2984@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2MJA9@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine Phosphotransfer domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,sCache_2 k141_9882_2 1278309.KB907101_gene790 1.05e-93 280.0 COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,1RQF9@1236|Gammaproteobacteria,1XI0D@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the hyi family hyi - 5.3.1.22,5.3.1.35 ko:K01816,ko:K22131 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 k141_2938_2 1288826.MSNKSG1_18205 4.82e-88 258.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,466ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_2938_3 1288826.MSNKSG1_18210 3.99e-282 771.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,464TP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_3643_1 1504672.669785140 9.39e-57 186.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,4AA74@80864|Comamonadaceae 28216|Betaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_3643_2 266779.Meso_1126 3.45e-52 168.0 COG3832@1|root,COG3832@2|Bacteria,1RD0P@1224|Proteobacteria,2U79U@28211|Alphaproteobacteria,43RFS@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Activator of Hsp90 - - - - - - - - - - - - AHSA1 k141_19666_1 522306.CAP2UW1_0935 2.75e-46 161.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase spkD - - - - - - - - - - - Pkinase k141_5759_1 391616.OA238_c18460 1.03e-39 139.0 COG0106@1|root,COG0106@2|Bacteria,1R41G@1224|Proteobacteria,2U0NV@28211|Alphaproteobacteria 28211|Alphaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA2 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_5001_1 1336237.JAEE01000001_gene2111 4.71e-20 89.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2 k141_2230_2 1026882.MAMP_02535 1.91e-138 411.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZPC@72273|Thiotrichales 72273|Thiotrichales G PFAM alpha amylase, catalytic - - 2.4.1.4 ko:K05341 ko00500,map00500 - R01823 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_849_1 653733.Selin_1230 4.94e-26 113.0 COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K02030,ko:K07679 ko02020,ko05133,map02020,map05133 M00236,M00477 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 3.A.1.3 - - HATPase_c,HisKA,SBP_bac_3 k141_4336_1 314345.SPV1_07009 1.05e-18 83.6 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_4336_2 1042375.AFPL01000055_gene2259 1.55e-64 213.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,465JY@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_17570_1 472759.Nhal_0708 3.46e-84 265.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales 135613|Chromatiales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_7835_1 1278309.KB907100_gene2253 2.75e-07 50.4 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XJCI@135619|Oceanospirillales 135619|Oceanospirillales L DNA-3-methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_7835_2 1278309.KB907100_gene2252 8.56e-164 466.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1XHM9@135619|Oceanospirillales 135619|Oceanospirillales G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_122_1 1278309.KB907099_gene2582 3.28e-72 239.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQAF@1236|Gammaproteobacteria,1XI9H@135619|Oceanospirillales 135619|Oceanospirillales NT Nitrate and nitrite sensing - - - - - - - - - - - - MCPsignal,NIT k141_13410_1 1278309.KB907102_gene49 8.8e-293 815.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XI39@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein - - - ko:K07121 - - - - ko00000 - - - LppC k141_13410_2 110662.Syncc9605_1186 1.05e-07 54.3 COG0792@1|root,COG0792@2|Bacteria,1G7PN@1117|Cyanobacteria,1H1DM@1129|Synechococcus 1117|Cyanobacteria L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_13410_3 1278309.KB907102_gene48 2.22e-74 226.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XI6S@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_10623_1 1500893.JQNB01000001_gene361 1.77e-167 473.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_8513_1 265729.GS18_0202985 3.71e-18 81.3 COG3278@1|root,COG3278@2|Bacteria,1VAHS@1239|Firmicutes,4HKKG@91061|Bacilli,1ZID0@1386|Bacillus 91061|Bacilli O COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - - - - - - - - - - COX1 k141_16167_1 1234364.AMSF01000064_gene2197 3.33e-82 249.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,1X6B8@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_15522_1 390235.PputW619_4072 1.69e-23 100.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1YW9W@136845|Pseudomonas putida group 1236|Gammaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD k141_7122_2 1288826.MSNKSG1_07043 4.68e-238 662.0 COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,4654Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) mdoG GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - ko:K03670 - - - - ko00000 - - - MdoG k141_2939_1 1004785.AMBLS11_16780 1.2e-48 162.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,464ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria D ATPase involved in cell division ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_14106_1 391593.RCCS2_12354 9.16e-37 135.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2P2BT@2433|Roseobacter 28211|Alphaproteobacteria H COG3572 Gamma-glutamylcysteine synthetase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 k141_14106_2 1122925.KB895393_gene1641 1.57e-20 87.4 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes,4HMMJ@91061|Bacilli,26YMS@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 k141_14106_3 314271.RB2654_17486 2.47e-10 60.1 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_12695_1 1158146.KB907132_gene75 9.87e-205 583.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_1540_1 1123368.AUIS01000003_gene1771 5.09e-217 610.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,2NC7Q@225057|Acidithiobacillales 225057|Acidithiobacillales P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_21732_2 395494.Galf_0103 1.38e-119 354.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2W9A5@28216|Betaproteobacteria,44WGW@713636|Nitrosomonadales 28216|Betaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - - k141_21732_3 1120998.AUFC01000001_gene1988 3.7e-10 61.2 COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia 186801|Clostridia T Histidine kinase - - - - - - - - - - - - AAA_16,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase k141_20400_1 743299.Acife_1337 9.38e-79 262.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_4,Response_reg k141_10624_1 768671.ThimaDRAFT_1403 4.08e-80 255.0 COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,1RNFZ@1236|Gammaproteobacteria,1WVYP@135613|Chromatiales 135613|Chromatiales G alpha beta alpha domain I - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_13411_1 1278309.KB907100_gene2024 9.84e-28 100.0 2EBXJ@1|root,335WX@2|Bacteria,1NAV5@1224|Proteobacteria,1SE3N@1236|Gammaproteobacteria,1XMVH@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_13411_2 1278309.KB907100_gene2023 7.58e-56 174.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1XKFC@135619|Oceanospirillales 135619|Oceanospirillales O accelerates isomerization of the peptidyl prolyl bond - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_11341_2 317025.Tcr_1367 1.75e-56 185.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,45ZNU@72273|Thiotrichales 72273|Thiotrichales H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_19668_1 870187.Thini_4031 6.12e-38 137.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,461JJ@72273|Thiotrichales 72273|Thiotrichales I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_7123_2 1095769.CAHF01000006_gene1858 2.26e-60 197.0 COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2VRGI@28216|Betaproteobacteria,477X3@75682|Oxalobacteraceae 28216|Betaproteobacteria S Predicted metal-binding integral membrane protein (DUF2182) - - - - - - - - - - - - DUF2182 k141_17571_1 225849.swp_1792 5.2e-28 103.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,2QBX4@267890|Shewanellaceae 1236|Gammaproteobacteria T PFAM CBS domain containing protein - - - - - - - - - - - - CBS k141_17571_2 396588.Tgr7_0629 1.35e-22 93.2 COG0526@1|root,COG0526@2|Bacteria,1NC9Q@1224|Proteobacteria,1T0R2@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Thioredoxin k141_17571_3 523791.Kkor_0701 2.34e-56 181.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XJIY@135619|Oceanospirillales 135619|Oceanospirillales V Negative regulator of beta-lactamase expression ampD - 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 k141_21118_1 1249627.D779_2044 4.1e-22 99.4 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,1WXBS@135613|Chromatiales 135613|Chromatiales M NlpB/DapX lipoprotein - - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_21118_2 1255043.TVNIR_3439 6.8e-139 403.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_21118_3 1123392.AQWL01000004_gene2693 3.31e-25 102.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,2VN1T@28216|Betaproteobacteria 28216|Betaproteobacteria C Galactose-1-phosphate uridyl transferase, N-terminal domain galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - DUF4921,GalP_UDP_tr_C,GalP_UDP_transf k141_10625_1 765914.ThisiDRAFT_2057 2.49e-71 233.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1WWCY@135613|Chromatiales 135613|Chromatiales G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_852_1 1532557.JL37_23925 9.42e-37 142.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3T1CY@506|Alcaligenaceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenases fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_4339_1 1537994.JQFW01000031_gene965 2.72e-94 292.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,46444@72275|Alteromonadaceae 1236|Gammaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_2940_1 2340.JV46_25920 1.11e-34 129.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1J7PM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_2940_2 1116472.MGMO_55c00170 9.57e-77 239.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XE9S@135618|Methylococcales 135618|Methylococcales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_5002_2 204773.HEAR1408 4.07e-08 58.9 2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,474TJ@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF3306) - - - - - - - - - - - - DUF3306 k141_5002_3 472759.Nhal_1622 5.34e-45 165.0 COG1145@1|root,COG1148@1|root,COG1145@2|Bacteria,COG1148@2|Bacteria,1MWHY@1224|Proteobacteria,1RZ4B@1236|Gammaproteobacteria,1X06U@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Fer4 k141_16168_1 1123237.Salmuc_03926 7.5e-55 181.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria 2|Bacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 ko:K03438,ko:K13292 - - - - ko00000,ko01000,ko03009 - - - LGT k141_16168_2 290400.Jann_2492 3.95e-20 85.5 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DedA family dedA - - - - - - - - - - - SNARE_assoc k141_17572_1 205922.Pfl01_4163 1.86e-47 163.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1YMKJ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria OU peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_125_1 314232.SKA53_00090 8.93e-154 439.0 COG1638@1|root,COG1638@2|Bacteria,1MUBS@1224|Proteobacteria,2TUKV@28211|Alphaproteobacteria,2P9YT@245186|Loktanella 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_14107_2 1215092.PA6_017_01020 2.7e-32 124.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1YCWH@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family ttgA - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD,HlyD_D23 k141_11342_1 1088721.NSU_0586 1.54e-85 267.0 COG0019@1|root,COG0019@2|Bacteria,1R4VG@1224|Proteobacteria,2U4JW@28211|Alphaproteobacteria,2K8KY@204457|Sphingomonadales 204457|Sphingomonadales E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_14804_1 1396858.Q666_12820 5e-175 503.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,46A2Y@72275|Alteromonadaceae 1236|Gammaproteobacteria CI Conserved carboxylase domain oadA - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5346 Biotin_lipoyl,HMGL-like,PYC_OADA k141_14804_2 1298593.TOL_3176 8.24e-190 536.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1XH8J@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_21119_1 396588.Tgr7_2195 9.17e-51 167.0 COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria,1WVZM@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11,Fer4_7 k141_21119_2 413404.Rmag_0859 3.6e-36 133.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1SMKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_17573_1 1125863.JAFN01000001_gene2402 3.86e-12 66.2 2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,42TNH@68525|delta/epsilon subdivisions,2WQ32@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 k141_7242_1 1165096.ARWF01000001_gene212 8.34e-72 232.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,2KKUI@206350|Nitrosomonadales 206350|Nitrosomonadales G PFAM Phosphoglucose isomerase pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_21228_1 458817.Shal_0059 4.64e-57 200.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAI3@267890|Shewanellaceae 1236|Gammaproteobacteria NT PFAM histidine kinase, HAMP region domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_3 k141_16263_1 349521.HCH_01608 1.51e-37 135.0 COG4619@1|root,COG4619@2|Bacteria,1QTWV@1224|Proteobacteria,1S627@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam ABC transporter - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_4485_1 1288826.MSNKSG1_07323 1.54e-126 363.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,467DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_4485_2 1288826.MSNKSG1_07328 5.83e-159 446.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,466E9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_4485_3 1288826.MSNKSG1_07333 3.92e-287 785.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,4649Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_4485_4 1288826.MSNKSG1_07338 3.2e-129 368.0 2E62S@1|root,330RV@2|Bacteria,1N7P9@1224|Proteobacteria,1SCEA@1236|Gammaproteobacteria,468TF@72275|Alteromonadaceae 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_4485_5 1288826.MSNKSG1_07343 1.3e-62 192.0 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,468YW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5129_1 522306.CAP2UW1_2957 3.66e-05 46.6 COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,1KQ6E@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_17,Fer4_8,RnfC_N,SLBB k141_5129_2 1137799.GZ78_06360 1.38e-28 113.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1XH3W@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_7971_2 1123368.AUIS01000031_gene1415 2.49e-44 147.0 2ECQ3@1|root,31692@2|Bacteria,1PX3E@1224|Proteobacteria,1T8SY@1236|Gammaproteobacteria,2NDD8@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - k141_7971_3 983545.Glaag_0187 2.57e-62 200.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1RZ28@1236|Gammaproteobacteria,467IY@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA k141_7971_4 1232410.KI421413_gene788 1.58e-52 173.0 COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,42W0S@68525|delta/epsilon subdivisions,2WRFW@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Bacterial regulatory proteins, tetR family - - - ko:K03577 - M00647 - - ko00000,ko00002,ko03000 - - - TetR_N k141_7971_5 767434.Fraau_1691 9.71e-23 89.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1X8KE@135614|Xanthomonadales 135614|Xanthomonadales K COG1278 Cold shock proteins - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_5846_1 927704.SELR_20790 0.000237 48.5 COG2831@1|root,COG2831@2|Bacteria 2|Bacteria U hemolysin activation secretion protein - - - - - - - - - - - - POTRA_2,ShlB k141_19773_1 1123511.KB905872_gene1845 9.59e-94 286.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H53T@909932|Negativicutes 909932|Negativicutes L RNA-directed DNA polymerase - - - - - - - - - - - - GIIM,RVT_1 k141_9292_1 1085623.GNIT_0561 7.41e-05 48.9 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,464KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_20533_1 1198232.CYCME_2266 2.55e-115 343.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,45ZY3@72273|Thiotrichales 72273|Thiotrichales U PFAM Bacterial type II secretion system protein F domain pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_15606_1 1042375.AFPL01000012_gene701 5.11e-117 341.0 COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,1S4Z5@1236|Gammaproteobacteria,46B0Y@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_15606_2 1042375.AFPL01000012_gene702 3.62e-40 134.0 COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,46BKY@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Phosphopantetheine attachment site RS00794 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_15606_3 1042375.AFPL01000012_gene703 1.14e-41 137.0 COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,1SC83@1236|Gammaproteobacteria,46BMU@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP2 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_15606_4 1151116.Q7S_04250 4.55e-09 58.9 COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,1S9TC@1236|Gammaproteobacteria,3FG8V@34037|Rahnella 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - IspA k141_13501_1 1288826.MSNKSG1_16281 6.98e-171 498.0 COG3127@1|root,COG3127@2|Bacteria,1QXGA@1224|Proteobacteria,1T3BG@1236|Gammaproteobacteria,467CX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_13501_2 1288826.MSNKSG1_16276 1.53e-147 417.0 COG1136@1|root,COG1136@2|Bacteria,1QU8Q@1224|Proteobacteria,1T3BF@1236|Gammaproteobacteria,46D5G@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_13501_3 1288826.MSNKSG1_16271 9.71e-47 166.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_3076_1 1279019.ARQK01000059_gene928 6.26e-14 80.1 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales 135613|Chromatiales M PFAM AsmA family protein - - - ko:K07289 - - - - ko00000 - - - AsmA k141_256_1 247633.GP2143_02135 9.84e-70 219.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1J4QD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_21888_1 1278309.KB907102_gene67 3.35e-48 164.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1XIP2@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_21888_2 1278309.KB907102_gene68 3.84e-301 827.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1XH8C@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_21888_3 1278309.KB907102_gene69 4.41e-165 467.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XHNJ@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_1686_1 1123393.KB891316_gene1745 3.3e-68 236.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria 28216|Betaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9,dCache_1 k141_14201_1 713586.KB900536_gene1923 2.38e-178 521.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_18394_1 374847.Kcr_0678 1.26e-44 150.0 2DZ77@1|root,2N5BN@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k141_18394_2 391600.ABRU01000056_gene520 6.64e-86 261.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,2KF5S@204458|Caulobacterales 204458|Caulobacterales S VIT family - - - - - - - - - - - - VIT1 k141_18394_3 1042163.BRLA_c023570 2.64e-11 61.6 COG5470@1|root,COG5470@2|Bacteria,1VSV2@1239|Firmicutes,4HUUN@91061|Bacilli,26X9M@186822|Paenibacillaceae 91061|Bacilli S NIPSNAP family containing protein - - - - - - - - - - - - - k141_5847_1 768671.ThimaDRAFT_0819 4.96e-66 211.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1WWMU@135613|Chromatiales 135613|Chromatiales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_962_1 264198.Reut_B4088 8.95e-33 133.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,1K004@119060|Burkholderiaceae 28216|Betaproteobacteria M RND efflux system, outer membrane lipoprotein, NodT family - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP k141_19774_1 1168067.JAGP01000001_gene364 2.9e-85 261.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,45ZZM@72273|Thiotrichales 72273|Thiotrichales H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_6492_1 1396858.Q666_16220 6.27e-112 327.0 COG0599@1|root,COG0599@2|Bacteria,1NN7W@1224|Proteobacteria,1T6AV@1236|Gammaproteobacteria,46BRR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD k141_3077_1 1996.JOFO01000040_gene5122 0.000193 45.1 COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4EM56@85012|Streptosporangiales 201174|Actinobacteria M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k141_257_1 1218084.BBJK01000120_gene6912 5.92e-56 194.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae 28216|Betaproteobacteria I Phospholipase D Transphosphatidylase - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_7973_1 272632.MSC_1068 5.7e-14 65.5 COG0230@1|root,COG0230@2|Bacteria 2|Bacteria J Ribosomal protein L34 rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 k141_963_2 1131814.JAFO01000001_gene3523 1.05e-32 124.0 COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U1NZ@28211|Alphaproteobacteria,3F2D7@335928|Xanthobacteraceae 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - 1.1.1.29,1.1.1.399,1.1.1.95 ko:K00018,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020,M00346 R00717,R01388,R01513 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_1687_1 1366046.HIMB11_00346 3.31e-132 383.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3ZGJY@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Belongs to the LDH2 MDH2 oxidoreductase family comC - 1.1.1.338 ko:K16844 ko00270,ko01120,map00270,map01120 - R07137 RC00031 ko00000,ko00001,ko01000 - - - Ldh_2 k141_2329_1 1278309.KB907106_gene1228 8.07e-44 158.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XH5X@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_2329_2 1278309.KB907106_gene1227 3.15e-110 329.0 COG1639@1|root,COG1639@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,1XI83@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein - - - - - - - - - - - - HDOD k141_9978_1 1127673.GLIP_2933 2.71e-139 408.0 COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,46D8K@72275|Alteromonadaceae 1236|Gammaproteobacteria I Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 k141_9978_2 1219035.NT2_02_04400 1.16e-12 73.6 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales 204457|Sphingomonadales M synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_10751_1 1122182.KB903819_gene180 2.81e-39 142.0 COG0465@1|root,COG0465@2|Bacteria,2I2U8@201174|Actinobacteria,4DBYF@85008|Micromonosporales 201174|Actinobacteria O Holliday junction DNA helicase ruvB N-terminus ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41,TPR_19,TPR_20 k141_20535_1 1489678.RDMS_02200 1.06e-12 69.7 COG2738@1|root,COG2738@2|Bacteria,1WJ1Z@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM peptidase, membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_3078_1 566466.NOR53_2879 1.75e-66 223.0 COG1502@1|root,COG1502@2|Bacteria,1NVR8@1224|Proteobacteria 1224|Proteobacteria I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_5849_1 697282.Mettu_3673 1.38e-55 177.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XF6D@135618|Methylococcales 135618|Methylococcales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_18395_1 519989.ECTPHS_02399 2.07e-125 368.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_9999_1 1027273.GZ77_17840 1.35e-36 135.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales 135619|Oceanospirillales J SAM-dependent - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_7988_1 264462.Bd0888 4.44e-131 407.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MSRN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria 213481|Bdellovibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_17726_1 349521.HCH_06737 1.22e-29 109.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1XPEX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_17726_2 314285.KT71_13694 0.0 1115.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J57S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_21900_1 498211.CJA_2763 4.16e-13 77.8 COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,1N5RS@1224|Proteobacteria,1RSMD@1236|Gammaproteobacteria,1FHVH@10|Cellvibrio 1236|Gammaproteobacteria G Glycosyl hydrolase catalytic core lamA - - - - - - - - - - - CBM_6,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_cc,PKD k141_1704_1 1288826.MSNKSG1_05978 2.57e-126 360.0 COG2050@1|root,COG2050@2|Bacteria,1RJ5Q@1224|Proteobacteria,1SB58@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Putative thioesterase (yiiD_Cterm) - - - - - - - - - - - - DUF4442 k141_1704_2 1288826.MSNKSG1_05983 6.19e-209 578.0 COG0834@1|root,COG0834@2|Bacteria,1RD01@1224|Proteobacteria,1S88T@1236|Gammaproteobacteria,467VB@72275|Alteromonadaceae 1236|Gammaproteobacteria ET ABC-type amino acid transport signal transduction systems periplasmic component domain - - - - - - - - - - - - SBP_bac_3 k141_2341_1 1211579.PP4_51530 1.68e-97 307.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1YWBP@136845|Pseudomonas putida group 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_7263_1 1163617.SCD_n01908 5.01e-86 260.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria 28216|Betaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_7989_2 1209072.ALBT01000023_gene4078 1.72e-06 50.1 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1FG8P@10|Cellvibrio 1236|Gammaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 k141_9310_1 243159.AFE_0787 1.6e-40 146.0 COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,1S5G3@1236|Gammaproteobacteria,2NDRP@225057|Acidithiobacillales 225057|Acidithiobacillales G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_5859_1 713586.KB900536_gene2579 2.64e-111 331.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_3770_1 95619.PM1_0209410 2.47e-90 286.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_978_1 555778.Hneap_2070 8.58e-101 308.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21901_1 388401.RB2150_03314 5.89e-103 322.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,3ZGS1@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Formate dehydrogenase, alpha subunit fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_5138_2 1168067.JAGP01000001_gene224 1.48e-105 308.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,4605S@72273|Thiotrichales 72273|Thiotrichales EH Glutamine amidotransferase of anthranilate synthase - - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_5138_3 857087.Metme_4596 1.64e-191 544.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XEVV@135618|Methylococcales 135618|Methylococcales EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_16999_1 857087.Metme_4604 9.44e-70 217.0 COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1XE85@135618|Methylococcales 135618|Methylococcales C Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC - 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - - k141_16999_2 1232683.ADIMK_0698 2.51e-72 228.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,467E5@72275|Alteromonadaceae 1236|Gammaproteobacteria P ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_2342_1 1000565.METUNv1_01732 1.74e-46 163.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,2KZ75@206389|Rhodocyclales 206389|Rhodocyclales S Pfam:Gp37_Gp68 - - - - - - - - - - - - DUF5131 k141_14916_1 1121921.KB898709_gene140 2.85e-66 213.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,2PMWK@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria P Rhodanese Homology Domain rhdA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_20549_1 388401.RB2150_03539 1.12e-42 150.0 COG0717@1|root,COG0717@2|Bacteria,1MVDH@1224|Proteobacteria,2TR5U@28211|Alphaproteobacteria,3ZG4K@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria F 2'-deoxycytidine 5'-triphosphate deaminase dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD k141_20549_2 388399.SSE37_04685 8.24e-46 163.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator, MerR family merR - - - - - - - - - - - MerR_1 k141_20549_3 367336.OM2255_12707 3.61e-53 168.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA - - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_3091_2 1288826.MSNKSG1_10198 5.92e-85 256.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,1RMWJ@1236|Gammaproteobacteria,468SR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the HpcH HpaI aldolase family rhmA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016829,GO:0016830,GO:0016832,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0071704 4.1.2.52,4.1.2.53 ko:K02510,ko:K12660 ko00051,ko00350,ko01120,map00051,map00350,map01120 - R01645,R01647,R02261 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_2049 HpcH_HpaI k141_11449_1 1461694.ATO9_14925 2.03e-105 309.0 COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,2TUIH@28211|Alphaproteobacteria,2PCN8@252301|Oceanicola 28211|Alphaproteobacteria K WHG domain MA20_04045 - - - - - - - - - - - TetR_N,WHG k141_11449_2 666509.RCA23_c17000 1.7e-40 138.0 2AS6X@1|root,31HJW@2|Bacteria,1RGYJ@1224|Proteobacteria,2U9UH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2852) MA20_04040 - - - - - - - - - - - DUF2852 k141_1114_2 1278309.KB907103_gene1087 4.82e-294 825.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1XIND@135619|Oceanospirillales 135619|Oceanospirillales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k141_1114_3 1278309.KB907103_gene1086 2.42e-82 251.0 COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1XJ5V@135619|Oceanospirillales 135619|Oceanospirillales L COG0084 Mg-dependent DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_11547_1 225937.HP15_568 1.15e-134 391.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,464DY@72275|Alteromonadaceae 1236|Gammaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_11547_2 1288826.MSNKSG1_00156 3.71e-197 546.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,464U9@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_11547_3 1288826.MSNKSG1_00151 1.68e-227 627.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4659J@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_11547_4 1288826.MSNKSG1_00146 0.0 935.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,465HW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_11547_5 1288826.MSNKSG1_00141 1.28e-252 694.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 k141_11547_6 1288826.MSNKSG1_00136 7.89e-68 216.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,4645C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell division ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_5276_1 1121949.AQXT01000002_gene1008 2.24e-23 99.8 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U148@28211|Alphaproteobacteria,43WNJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Bacterial sugar transferase - - 2.7.8.40 ko:K21303 - - - - ko00000,ko01000,ko01003,ko01005 - - - Bac_transf k141_5276_2 395493.BegalDRAFT_2231 1.63e-148 430.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,461RD@72273|Thiotrichales 72273|Thiotrichales E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k141_8136_2 1123279.ATUS01000001_gene909 9.01e-104 310.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1J4GT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_19264_1 1211114.ALIP01000041_gene448 4.24e-31 120.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1X3I1@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_414_1 1249627.D779_0932 6.62e-26 107.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_414_2 574966.KB898647_gene2580 1.08e-26 108.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1XKNX@135619|Oceanospirillales 135619|Oceanospirillales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB k141_11562_2 666685.R2APBS1_3704 2.6e-52 182.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1S48Z@1236|Gammaproteobacteria,1X3YW@135614|Xanthomonadales 135614|Xanthomonadales M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_3237_1 580332.Slit_1782 2.22e-58 194.0 COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria 1224|Proteobacteria T response regulator - - - - - - - - - - - - Guanylate_cyc,HATPase_c,HisKA,Response_reg k141_3237_2 930169.B5T_03261 8.61e-131 378.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XHPG@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_21350_1 1122137.AQXF01000001_gene3182 1.83e-106 321.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains luxO - - ko:K10912 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_10149_1 1178482.BJB45_06800 2.47e-91 268.0 28MA6@1|root,2ZANZ@2|Bacteria,1MVM9@1224|Proteobacteria,1S049@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10149_2 1288826.MSNKSG1_14247 3.73e-78 232.0 COG0590@1|root,COG0590@2|Bacteria,1QHSD@1224|Proteobacteria,1SWCJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria FJ protein of Pasteurellaceae UniRef RepID Q9CKQ4_PASMU Z012_01525 - - - - - - - - - - - - k141_10149_3 1288826.MSNKSG1_14242 1.17e-239 662.0 COG0477@1|root,COG2814@2|Bacteria,1MVTM@1224|Proteobacteria,1RR5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_5965_1 713586.KB900536_gene1884 2.91e-120 363.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_17863_2 977880.RALTA_B1139 1.56e-75 237.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,1K00W@119060|Burkholderiaceae 28216|Betaproteobacteria P Ammonium transporter - - - ko:K03320,ko:K06580 - - - - ko00000,ko02000,ko04090 1.A.11,1.A.11.4 - - Ammonium_transp k141_8144_1 1260251.SPISAL_06490 9.5e-44 155.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1WWHF@135613|Chromatiales 135613|Chromatiales EGP Major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_5298_1 1131553.JIBI01000019_gene496 5.62e-80 254.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,371WD@32003|Nitrosomonadales 28216|Betaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10,6.3.2.13 ko:K01929,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_5298_2 1049564.TevJSym_aj00350 5.44e-119 360.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1J4PM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_8755_1 395493.BegalDRAFT_2881 2.66e-69 231.0 COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,1RS1G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C TIGRFAM SagB-type dehydrogenase domain - - - - - - - - - - - - Nitroreductase k141_426_1 1278309.KB907106_gene1234 5.94e-160 449.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XHNR@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter aapP - - ko:K09972 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k141_13671_1 1249627.D779_2182 3.94e-69 213.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales 135613|Chromatiales S Belongs to the WrbA family - - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_13671_2 1026882.MAMP_02913 1.28e-19 85.5 COG3308@1|root,COG3308@2|Bacteria,1N5UB@1224|Proteobacteria,1SAAJ@1236|Gammaproteobacteria,4634G@72273|Thiotrichales 72273|Thiotrichales S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_13671_3 1122194.AUHU01000007_gene280 3.75e-61 197.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_16408_1 1278309.KB907099_gene2778 4.68e-154 435.0 COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,1S64F@1236|Gammaproteobacteria,1XRX0@135619|Oceanospirillales 135619|Oceanospirillales I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 k141_16408_2 391625.PPSIR1_36127 3.81e-94 292.0 COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,42QG0@68525|delta/epsilon subdivisions,2WJE5@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Protein of unknown function (DUF2817) - - - - - - - - - - - - Peptidase_M14 k141_11563_1 519989.ECTPHS_06737 1.98e-70 228.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales 135613|Chromatiales HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - ATP-grasp_3,RLAN,RimK k141_1130_3 1049564.TevJSym_at00400 4.99e-42 148.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1J6XG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_1130_4 314282.PCNPT3_07580 1.26e-22 92.4 COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane protein domain - - - - - - - - - - - - DUF4339,RDD k141_12291_1 317025.Tcr_1697 4.35e-19 86.7 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,4609U@72273|Thiotrichales 72273|Thiotrichales L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_12291_2 1168067.JAGP01000001_gene496 1.28e-20 88.6 COG1639@1|root,COG1639@2|Bacteria 2|Bacteria T HDOD domain - - - - - - - - - - - - HDOD,Response_reg k141_3238_1 1288826.MSNKSG1_11428 1.52e-130 405.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_1818_1 1122599.AUGR01000015_gene2711 4.39e-29 119.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_1818_2 292415.Tbd_1060 6.93e-34 120.0 2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,2W8F1@28216|Betaproteobacteria,1KT4D@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_20645_1 1278309.KB907107_gene1661 7.17e-104 301.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1XJZ9@135619|Oceanospirillales 135619|Oceanospirillales H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_20645_2 1278309.KB907107_gene1662 1.9e-10 57.4 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_4617_1 1249627.D779_3935 3.32e-110 331.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P k141_4617_2 998674.ATTE01000001_gene584 7.2e-48 158.0 COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,460M2@72273|Thiotrichales 72273|Thiotrichales O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin k141_427_1 266809.PM03_04210 9.54e-26 97.4 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2UJKX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_427_2 314262.MED193_05331 9.23e-68 209.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2P2XH@2433|Roseobacter 28211|Alphaproteobacteria J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_21352_1 1278309.KB907099_gene2899 4.16e-95 289.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XHND@135619|Oceanospirillales 135619|Oceanospirillales M COG2230 Cyclopropane fatty acid synthase and related methyltransferases - - - - - - - - - - - - CMAS k141_8146_1 1121923.GPUN_2313 1.88e-100 298.0 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,46580@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep_2,THDPS_M,THDPS_N k141_5299_1 1278309.KB907099_gene3030 4.88e-43 148.0 2E5B0@1|root,33033@2|Bacteria,1ND0X@1224|Proteobacteria,1SEBX@1236|Gammaproteobacteria,1XMD6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5299_2 1278309.KB907099_gene3029 3.41e-66 204.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1XK21@135619|Oceanospirillales 135619|Oceanospirillales S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 k141_12292_2 1049564.TevJSym_aj00710 7.26e-36 137.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Von willebrand factor, type a cbbO - - - - - - - - - - - VWA k141_7375_1 1042377.AFPJ01000023_gene657 1.38e-87 297.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_15034_1 525904.Tter_1969 1.69e-71 233.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_15034_2 561229.Dd1591_2741 4.22e-107 319.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1S0KW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Molecular chaperone GroES - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_19282_1 1278309.KB907107_gene1659 1.52e-100 310.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1XHE3@135619|Oceanospirillales 135619|Oceanospirillales O COG0501 Zn-dependent protease with chaperone function - - - - - - - - - - - - Peptidase_M48 k141_19282_2 1278309.KB907107_gene1660 3.16e-108 314.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1XI0A@135619|Oceanospirillales 135619|Oceanospirillales S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA k141_10898_1 367336.OM2255_08476 2.78e-104 321.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_2489_1 1278309.KB907101_gene383 1.79e-13 68.9 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,1S453@1236|Gammaproteobacteria,1XKBG@135619|Oceanospirillales 135619|Oceanospirillales S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 k141_2489_2 1278309.KB907099_gene2998 5.13e-289 804.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,1XHDA@135619|Oceanospirillales 135619|Oceanospirillales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_19902_1 990073.ATHU01000001_gene432 4.64e-48 177.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 k141_19902_2 670487.Ocepr_0084 1.58e-64 215.0 COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus 2|Bacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_8147_1 388401.RB2150_03314 1.45e-125 383.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,3ZGS1@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Formate dehydrogenase, alpha subunit fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_3870_1 395493.BegalDRAFT_1882 1.39e-44 149.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,460R3@72273|Thiotrichales 72273|Thiotrichales C NADH dehydrogenase nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_3870_2 713586.KB900536_gene3046 2.28e-167 476.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa k141_12293_1 293826.Amet_4761 1.43e-21 94.0 COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,36HF8@31979|Clostridiaceae 186801|Clostridia M Peptidase family M23 - - - - - - - - - - - - G5,LysM,Peptidase_M23 k141_18509_1 1288826.MSNKSG1_14682 2.36e-161 466.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,463YF@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components atmA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_18509_2 1288826.MSNKSG1_14677 0.0 1033.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,4658C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1132 ABC-type multidrug transport system, ATPase and permease components draA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_18509_3 1288826.MSNKSG1_14672 2.01e-302 825.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,469PM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_18509_4 1288826.MSNKSG1_14667 1.01e-174 488.0 2CH0A@1|root,2ZANK@2|Bacteria,1R6U4@1224|Proteobacteria,1RQ3J@1236|Gammaproteobacteria,466JM@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18509_5 1288826.MSNKSG1_14662 3.35e-185 536.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,464Q3@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_17116_1 472759.Nhal_3602 4.29e-220 612.0 COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1T0C7@1236|Gammaproteobacteria,1X2MB@135613|Chromatiales 135613|Chromatiales O Radical SAM superfamily - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_17116_3 713586.KB900536_gene315 8.97e-47 159.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1WWTZ@135613|Chromatiales 135613|Chromatiales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_428_1 926551.KB900715_gene2197 3.33e-15 83.2 COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,1HZ3X@117743|Flavobacteriia,1EQ4Q@1016|Capnocytophaga 976|Bacteroidetes S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - DUF3352 k141_8756_1 207954.MED92_02758 3.7e-122 355.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XH6D@135619|Oceanospirillales 135619|Oceanospirillales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_8756_2 95619.PM1_0210315 6.62e-60 194.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_16409_2 553171.HMPREF0648_1988 9.13e-11 68.9 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia 976|Bacteroidetes CO AhpC Tsa family - - - - - - - - - - - - AhpC-TSA,DUF4369,Thioredoxin_8 k141_22026_1 1123401.JHYQ01000005_gene268 5.71e-44 145.0 COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria 1236|Gammaproteobacteria P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_22026_2 870187.Thini_3763 3.65e-60 196.0 2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM CRISPR-associated protein - - - - - - - - - - - - Cas6 k141_22026_3 631362.Thi970DRAFT_01390 2.58e-18 77.4 2E3CD@1|root,32YBP@2|Bacteria,1N8PD@1224|Proteobacteria,1SCSK@1236|Gammaproteobacteria,1WZ7C@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_22026_4 870187.Thini_3765 6.93e-49 166.0 COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD k141_3239_1 1288826.MSNKSG1_08798 9.62e-233 662.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,4662T@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_13675_1 1123070.KB899261_gene2134 8.8e-38 145.0 COG0438@1|root,COG2908@1|root,COG0438@2|Bacteria,COG2908@2|Bacteria,46USQ@74201|Verrucomicrobia,2ITPS@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Metallophos k141_19283_1 270374.MELB17_20871 1.23e-42 152.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_17865_1 203122.Sde_2087 1.2e-18 84.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,4651F@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k141_21462_1 1278309.KB907099_gene2641 2.03e-280 830.0 COG0515@1|root,COG0642@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1T55X@1236|Gammaproteobacteria,1XI8Z@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg k141_4735_1 1283284.AZUK01000001_gene1556 4.9e-11 57.0 2DR8E@1|root,33ANS@2|Bacteria,1NI69@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_15131_1 1168067.JAGP01000001_gene749 2.12e-81 247.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,460Q6@72273|Thiotrichales 72273|Thiotrichales O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_3335_2 1249627.D779_4053 2.65e-129 374.0 COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,1S22U@1236|Gammaproteobacteria,1X0RX@135613|Chromatiales 135613|Chromatiales M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_5427_2 754476.Q7A_1014 2.73e-79 253.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,45ZS1@72273|Thiotrichales 72273|Thiotrichales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_12424_2 1452718.JBOY01000028_gene173 4.12e-23 97.1 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SBQN@1236|Gammaproteobacteria 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_8238_1 1123393.KB891331_gene2884 4.47e-20 84.7 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1KRR1@119069|Hydrogenophilales 119069|Hydrogenophilales E Dehydroquinase class II - - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_8238_2 316407.85676046 1.68e-45 152.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,3XM9J@561|Escherichia 1236|Gammaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - iYL1228.KPN_03664 Biotin_lipoyl k141_10270_1 1278309.KB907100_gene1986 2.14e-118 348.0 COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1XIBP@135619|Oceanospirillales 135619|Oceanospirillales E O-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_10270_2 1278309.KB907100_gene1985 2.07e-199 560.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1XHDD@135619|Oceanospirillales 135619|Oceanospirillales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_20714_1 393595.ABO_1273 1.2e-95 291.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1XHPF@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_11010_1 1432050.IE4771_CH00057 8.94e-24 97.4 COG1737@1|root,COG1737@2|Bacteria,1R6J5@1224|Proteobacteria,2U06P@28211|Alphaproteobacteria,4B9WH@82115|Rhizobiaceae 28211|Alphaproteobacteria K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS k141_11010_2 1469613.JT55_16645 4.55e-78 247.0 COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,2U18T@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC transporter substrate-binding protein - - - - - - - - - - - - SBP_bac_5 k141_1263_2 1121918.ARWE01000001_gene1363 5.59e-05 43.1 2DE4S@1|root,2ZKHD@2|Bacteria,1PAFE@1224|Proteobacteria,433S5@68525|delta/epsilon subdivisions,2WXQM@28221|Deltaproteobacteria,43VRD@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_22123_1 1278309.KB907099_gene2424 2.53e-50 171.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XHJ5@135619|Oceanospirillales 135619|Oceanospirillales O protease - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_22123_2 1278309.KB907099_gene2423 6.55e-104 303.0 COG1514@1|root,COG1514@2|Bacteria,1QEB7@1224|Proteobacteria,1S4QW@1236|Gammaproteobacteria,1XJSH@135619|Oceanospirillales 135619|Oceanospirillales J 2'-5' RNA ligase superfamily - - - - - - - - - - - - LigT_PEase k141_22123_3 1278309.KB907099_gene2422 2.9e-113 328.0 COG0625@1|root,COG0625@2|Bacteria,1PBD7@1224|Proteobacteria,1S5JR@1236|Gammaproteobacteria,1XJTZ@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_N k141_22123_4 1278309.KB907099_gene2421 1.51e-33 125.0 COG2959@1|root,COG2959@2|Bacteria,1N3SM@1224|Proteobacteria,1S9N7@1236|Gammaproteobacteria,1XME6@135619|Oceanospirillales 135619|Oceanospirillales H enzyme of heme biosynthesis - - - - - - - - - - - - - k141_13796_1 1437882.AZRU01000049_gene5269 6.51e-35 137.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,1YK2F@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235,PilZ k141_18634_1 1283300.ATXB01000002_gene2696 4.52e-33 133.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XFKT@135618|Methylococcales 135618|Methylococcales T PFAM Chemotaxis methyl-accepting receptor, signalling - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9,TarH k141_1923_1 90813.JQMT01000001_gene2048 6e-11 63.9 COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P k141_1923_2 396588.Tgr7_2583 1.33e-45 152.0 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,1X0YN@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_1923_3 396588.Tgr7_0462 9.28e-39 137.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S3GT@1236|Gammaproteobacteria,1X151@135613|Chromatiales 135613|Chromatiales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_5428_1 743721.Psesu_1279 6.42e-79 244.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1X315@135614|Xanthomonadales 135614|Xanthomonadales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_13101_1 1173263.Syn7502_00144 4.68e-74 242.0 COG0732@1|root,COG0732@2|Bacteria 2|Bacteria V type I restriction modification DNA specificity domain - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k141_13101_2 317619.ANKN01000149_gene1467 6.34e-66 210.0 COG0286@1|root,COG0286@2|Bacteria,1G70A@1117|Cyanobacteria 1117|Cyanobacteria V Type I restriction-modification system methyltransferase subunit - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HSDR_N_2,N6_Mtase k141_15132_1 371731.Rsw2DRAFT_3145 1.26e-33 124.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria,1FBIE@1060|Rhodobacter 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_15132_2 367336.OM2255_07925 1.12e-104 306.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_11011_1 1278309.KB907102_gene81 1.8e-122 364.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XHC9@135619|Oceanospirillales 135619|Oceanospirillales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_13797_1 1122201.AUAZ01000005_gene625 5.61e-114 355.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,464J4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_1924_1 1541065.JRFE01000012_gene2432 2.12e-79 252.0 COG1696@1|root,COG1696@2|Bacteria,1FZXB@1117|Cyanobacteria,3VJAD@52604|Pleurocapsales 1117|Cyanobacteria M MBOAT, membrane-bound O-acyltransferase family - - - - - - - - - - - - MBOAT k141_21464_1 349521.HCH_06546 1.9e-91 287.0 COG1672@1|root,COG1672@2|Bacteria,1R4PF@1224|Proteobacteria,1S5S6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Archaeal ATPase - - - - - - - - - - - - AAA_35 k141_8240_2 187272.Mlg_0886 1.92e-37 133.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1WWK4@135613|Chromatiales 135613|Chromatiales J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_13102_1 713586.KB900536_gene2639 1.9e-30 119.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_3337_1 1218084.BBJK01000034_gene3232 5.08e-41 149.0 COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,2W1S8@28216|Betaproteobacteria,1K5IY@119060|Burkholderiaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - Abhydrolase_1,GerE k141_7500_2 1232683.ADIMK_1436 7.07e-200 558.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,1S196@1236|Gammaproteobacteria,469A5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3445) - - 1.14.13.238 ko:K22342 - - - - ko00000,ko01000 - - - DUF3445 k141_7500_3 340177.Cag_0283 1.92e-32 116.0 COG2076@1|root,COG2076@2|Bacteria,1FFAP@1090|Chlorobi 1090|Chlorobi P PFAM small multidrug resistance protein - - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res k141_17997_1 232346.JHQL01000002_gene804 6.83e-118 350.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1XIA5@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_17997_2 713586.KB900536_gene134 9.94e-158 461.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales 135613|Chromatiales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_17997_3 472759.Nhal_2460 1.21e-27 112.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales 135613|Chromatiales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_20715_1 270374.MELB17_19044 9.46e-76 233.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,4640C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_20715_2 1121013.P873_12655 1.83e-36 125.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1X61R@135614|Xanthomonadales 135614|Xanthomonadales J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_6061_2 1278309.KB907099_gene2887 2.84e-164 468.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria,1XI6Q@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_6061_3 1122599.AUGR01000031_gene11 1.45e-79 240.0 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,1S934@1236|Gammaproteobacteria,1XJDC@135619|Oceanospirillales 135619|Oceanospirillales G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_6061_4 1278309.KB907101_gene676 3.06e-175 498.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,1XH4A@135619|Oceanospirillales 135619|Oceanospirillales G C4-dicarboxylate transport system - - - - - - - - - - - - DctM k141_6721_1 401526.TcarDRAFT_2737 2.12e-09 68.2 COG3307@1|root,COG3307@2|Bacteria,1V4DY@1239|Firmicutes,4H4E3@909932|Negativicutes 909932|Negativicutes M O-antigen polymerase - - - - - - - - - - - - Wzy_C k141_8241_1 929703.KE386491_gene883 1.83e-27 109.0 COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia 976|Bacteroidetes S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_8241_2 1121875.KB907551_gene952 7.91e-38 133.0 2C5NT@1|root,34B3U@2|Bacteria,4P671@976|Bacteroidetes,1IA9C@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_9503_1 1288826.MSNKSG1_15432 1.48e-126 364.0 COG2807@1|root,COG2807@2|Bacteria,1QU0F@1224|Proteobacteria,1T1JZ@1236|Gammaproteobacteria,469Z2@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0477 Permeases of the major facilitator superfamily yhjX - - - - - - - - - - - MFS_1 k141_9503_2 1288826.MSNKSG1_15437 1.41e-36 132.0 COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,1RS4Y@1236|Gammaproteobacteria,4668M@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2005 N-terminal domain of molybdenum-binding protein - - - - - - - - - - - - HTH_1,HTH_17,PBP_like k141_4737_1 1286106.MPL1_05884 9.13e-183 528.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales 72273|Thiotrichales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_11013_1 367336.OM2255_10565 2.37e-86 262.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT k141_18635_1 1121289.JHVL01000052_gene1552 4.3e-71 234.0 COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1V6MC@1239|Firmicutes,24JED@186801|Clostridia,36KXT@31979|Clostridiaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - GGDEF,SBP_bac_3,TPR_12 k141_21465_1 1288826.MSNKSG1_14407 5.09e-18 82.4 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T3JY@1236|Gammaproteobacteria,46891@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_21465_2 1288826.MSNKSG1_14412 6.44e-124 357.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_11021_2 395493.BegalDRAFT_0081 1.7e-139 401.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,460EX@72273|Thiotrichales 72273|Thiotrichales KO TIGRFAM Hydrogenase accessory protein HypB - - - ko:K04652 - - - - ko00000,ko03110 - - - cobW k141_11021_3 1049564.TevJSym_bc00300 2.04e-203 570.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1J9VF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Hydrogenase formation hypA family hypD GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - ko:K04654 - - - - ko00000 - - - HypD k141_9523_1 631454.N177_1532 9e-21 89.4 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,1JQDA@119043|Rhodobiaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain coxM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_9523_2 631454.N177_1533 1.53e-68 209.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,1JNZP@119043|Rhodobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain coxS - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 k141_12444_1 398578.Daci_2374 4.52e-08 52.8 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,4AE1M@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM CBS domain containing protein - - - - - - - - - - - - CBS k141_12444_2 1168065.DOK_07989 9.87e-89 274.0 COG4798@1|root,COG4798@2|Bacteria 2|Bacteria E methyltransferase - - - - - - - - - - - - Acetyltransf_1,DUF805,FAD_binding_4,Methyltransf_11 k141_19381_1 1121372.AULK01000014_gene1805 6.77e-33 123.0 COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4FMN2@85023|Microbacteriaceae 201174|Actinobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_19381_2 1194165.CAJF01000020_gene2934 8.28e-36 129.0 COG1402@1|root,COG1402@2|Bacteria 2|Bacteria I creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_6087_1 314278.NB231_12259 1.76e-101 323.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_10296_1 555778.Hneap_1771 2.76e-87 264.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1WWJ3@135613|Chromatiales 135613|Chromatiales N basal body rod protein - - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_11673_1 1227352.C173_18821 1.77e-27 116.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,26QJT@186822|Paenibacillaceae 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_2601_1 545276.KB898724_gene1813 9.56e-25 102.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_2601_2 1279017.AQYJ01000022_gene2675 4.3e-112 327.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,465AV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_15142_1 935863.AWZR01000013_gene1500 3.59e-38 139.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1X3SU@135614|Xanthomonadales 135614|Xanthomonadales K Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_3351_2 765913.ThidrDRAFT_2417 1.81e-79 249.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1WWKN@135613|Chromatiales 135613|Chromatiales C C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - k141_3351_3 2340.JV46_03580 3.62e-64 215.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Citrate transporter sac1 - - - - - - - - - - - CitMHS,TrkA_C k141_550_2 686340.Metal_0120 3.42e-05 51.6 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_13818_1 1042375.AFPL01000022_gene2633 4.63e-64 203.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,467TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_12445_2 366394.Smed_5134 4.99e-42 148.0 COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,2TV91@28211|Alphaproteobacteria,4BI91@82115|Rhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 MA20_30160 - - - - - - - - - - - DctP k141_18012_1 1129794.C427_0893 2.21e-20 90.5 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_2736_3 713586.KB900536_gene2550 3.54e-22 95.9 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cmeE - - ko:K03585,ko:K18901 ko01501,ko01503,map01501,map01503 M00646,M00647,M00698,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_14536_1 998674.ATTE01000001_gene4209 1.54e-49 172.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,463KW@72273|Thiotrichales 72273|Thiotrichales I Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,FA_desaturase k141_20058_1 745411.B3C1_19133 2.18e-86 269.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1J7B8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Transposase Z012_08285 - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_15207_1 1249627.D779_2787 1.06e-06 49.7 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1WWTH@135613|Chromatiales 135613|Chromatiales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_15207_2 981336.F944_01474 3.11e-33 128.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,3NIEI@468|Moraxellaceae 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_6821_1 506534.Rhein_1198 9.47e-44 151.0 COG0745@1|root,COG0745@2|Bacteria,1QWG0@1224|Proteobacteria 1224|Proteobacteria KT Pfam Response regulator receiver - - - - - - - - - - - - HTH_17,Response_reg k141_7650_1 1288826.MSNKSG1_10158 3.08e-250 689.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_7650_2 1288826.MSNKSG1_10153 1.84e-84 250.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,4678H@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1186 Protein chain release factor B yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_7650_3 1479237.JMLY01000001_gene3271 3.19e-64 196.0 2E4QK@1|root,32ZJ6@2|Bacteria,1N8KD@1224|Proteobacteria,1SDI7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7650_4 1288826.MSNKSG1_10143 5.05e-207 574.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1S0C5@1236|Gammaproteobacteria,469ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - GGDEF,Hemerythrin,PAS_3 k141_7650_6 225937.HP15_2753 1.26e-171 483.0 COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,1RQ7J@1236|Gammaproteobacteria,46B1G@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_19493_1 491952.Mar181_1233 1.94e-65 202.0 COG2193@1|root,COG2193@2|Bacteria,1RD4Y@1224|Proteobacteria,1S40G@1236|Gammaproteobacteria,1XJQH@135619|Oceanospirillales 135619|Oceanospirillales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_19493_2 400668.Mmwyl1_2836 7.4e-17 79.3 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales 135619|Oceanospirillales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_17393_1 697282.Mettu_3853 2.22e-25 100.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,1XFCP@135618|Methylococcales 135618|Methylococcales N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_17393_2 261292.Nit79A3_2959 2.31e-48 171.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,372QB@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_14555_1 1049564.TevJSym_bn00120 4.98e-71 219.0 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1JAMF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Phosphoribosyl transferase domain pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_7651_1 1239962.C943_00031 2.87e-80 266.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,47NAM@768503|Cytophagia 976|Bacteroidetes F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_9671_2 697282.Mettu_4019 2.92e-14 68.9 COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria,1XFH0@135618|Methylococcales 135618|Methylococcales S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease k141_4044_1 1288826.MSNKSG1_17031 3.97e-82 253.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,4662Y@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_4044_2 1288826.MSNKSG1_17026 1.98e-51 162.0 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,1S8S1@1236|Gammaproteobacteria,468WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775 ThiS k141_4044_3 1288826.MSNKSG1_17021 1.94e-98 286.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,467A9@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0314 Molybdopterin converting factor, large subunit moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1305,iEC042_1314.EC042_0869,iEC55989_1330.EC55989_0828,iECABU_c1320.ECABU_c08270,iECED1_1282.ECED1_0750,iECIAI1_1343.ECIAI1_0820,iECIAI39_1322.ECIAI39_0761,iECNA114_1301.ECNA114_0717,iECO103_1326.ECO103_0820,iECO111_1330.ECO111_0846,iECO26_1355.ECO26_0911,iECOK1_1307.ECOK1_0787,iECP_1309.ECP_0799,iECS88_1305.ECS88_0802,iECSE_1348.ECSE_0839,iECSF_1327.ECSF_0711,iECW_1372.ECW_m0841,iEKO11_1354.EKO11_3101,iEcE24377_1341.EcE24377A_0848,iG2583_1286.G2583_1013,iLF82_1304.LF82_1369,iNRG857_1313.NRG857_03500,iSSON_1240.SSON_0764,iUMN146_1321.UM146_13720,iUTI89_1310.UTI89_C0785,iWFL_1372.ECW_m0841,ic_1306.c0867 MoaE k141_4044_4 225937.HP15_4105 2.82e-05 46.6 2ETDD@1|root,33KX6@2|Bacteria,1NHJB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_4044_5 1288826.MSNKSG1_17011 1.34e-122 351.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,468M3@72275|Alteromonadaceae 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_4044_7 1288826.MSNKSG1_17001 4.4e-172 491.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,463ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643 HD,Ppx-GppA k141_2757_1 1288826.MSNKSG1_06793 1.38e-77 236.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46712@72275|Alteromonadaceae 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_2757_2 1288826.MSNKSG1_06798 3.13e-223 615.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,466U8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glucose-6-phosphate 1-epimerase family yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_2757_3 1288826.MSNKSG1_06803 2.72e-195 541.0 COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,1RQII@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase,DAGAT k141_2757_4 1288826.MSNKSG1_06808 1.53e-42 146.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_19494_1 314260.PB2503_10239 3.62e-12 63.9 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_19494_2 398580.Dshi_2154 9.53e-64 198.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03768,ko:K09565 ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145 - - - ko00000,ko00001,ko01000,ko03110 - - - Pro_isomerase k141_14556_1 493475.GARC_1499 3.74e-61 198.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,464EI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ribF family ribF GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0025,iJN746.PP_0602 FAD_syn,Flavokinase k141_7652_1 870187.Thini_3864 1.04e-06 48.1 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_7652_2 631362.Thi970DRAFT_03838 8.06e-48 166.0 COG2232@1|root,COG2232@2|Bacteria 2|Bacteria V ATP-grasp domain - - - - - - - - - - - - ATP-grasp_3 k141_9021_1 243159.AFE_3249 7.12e-73 234.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,2NBYQ@225057|Acidithiobacillales 225057|Acidithiobacillales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_9021_2 2340.JV46_03520 2.64e-183 516.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1J4P4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the phosphoglycerate kinase family pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSbBS512_1146.SbBS512_E3351 PGK k141_9672_1 553177.CAPSP0001_0171 1.81e-28 112.0 COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,1EQVS@1016|Capnocytophaga 976|Bacteroidetes H Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_9672_2 1347342.BN863_8160 1.89e-07 53.5 COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the BshC family bshC - - ko:K22136 - - - - ko00000 - - - BshC k141_20846_1 1288826.MSNKSG1_16156 1.38e-175 490.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RQ6C@1236|Gammaproteobacteria,46D51@72275|Alteromonadaceae 1236|Gammaproteobacteria HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_20846_2 1288826.MSNKSG1_16151 1.42e-203 566.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,465Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_20846_3 1288826.MSNKSG1_16146 5.17e-110 322.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,466A4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015889,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0031419,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - ko:K02016,ko:K06858 ko02010,map02010 M00240,M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13,3.A.1.14 - iECH74115_1262.ECH74115_0168,iECSP_1301.ECSP_0159,iECs_1301.ECs0162,iZ_1308.Z0169 Peripla_BP_2 k141_17394_1 396588.Tgr7_0350 2.25e-232 651.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales 135613|Chromatiales C reductase, alpha subunit - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_7653_1 626887.J057_22340 1.61e-39 144.0 COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,464G3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glycosyl transferase family, helical bundle domain ybiB GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_18801_1 1288826.MSNKSG1_03792 1.54e-73 231.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,464N2@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family fadA - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_18801_2 1288826.MSNKSG1_03787 0.0 1374.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,465MP@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_18801_3 1288826.MSNKSG1_03782 0.0 1400.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,4646K@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 k141_18801_4 1288826.MSNKSG1_03777 3.69e-140 400.0 COG1426@1|root,COG1426@2|Bacteria,1RIIX@1224|Proteobacteria,1S62E@1236|Gammaproteobacteria,46B8I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_18801_5 1288826.MSNKSG1_03772 3.2e-242 667.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,466PN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_18801_6 1288826.MSNKSG1_03767 0.0 882.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,465K9@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_18801_7 1288826.MSNKSG1_03762 6.39e-173 482.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k141_18801_8 1288826.MSNKSG1_03757 3.04e-162 454.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,4674M@72275|Alteromonadaceae 1236|Gammaproteobacteria S HAD-hyrolase-like gph GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006040,GO:0006082,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009254,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0030203,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097172,GO:1901135,GO:1901360,GO:1901564 3.1.3.105,3.1.3.18 ko:K01091,ko:K22292 ko00520,ko00630,ko01100,ko01110,ko01130,map00520,map00630,map01100,map01110,map01130 - R01334,R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_18801_9 1288826.MSNKSG1_03752 8.34e-175 488.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,46407@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yciK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short k141_18801_10 1288826.MSNKSG1_03747 1.97e-51 162.0 COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria,1SGAT@1236|Gammaproteobacteria,46903@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins XAC3035 - - - - - - - - - - - DUF836 k141_18801_11 1288826.MSNKSG1_03742 3.29e-184 512.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,4644D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_18801_12 1288826.MSNKSG1_03737 4.81e-36 122.0 2EH9I@1|root,33B1E@2|Bacteria,1NH43@1224|Proteobacteria,1SD9Y@1236|Gammaproteobacteria,4692W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2788) - - - - - - - - - - - - DUF2788 k141_18801_13 1288826.MSNKSG1_03732 2.27e-65 206.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,4650K@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k141_4045_1 472759.Nhal_3892 7.71e-47 171.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_9022_1 525257.HMPREF0204_14287 1.5e-50 171.0 COG4315@1|root,COG4315@2|Bacteria,4NI3N@976|Bacteroidetes,1HYWK@117743|Flavobacteriia,3ZPXH@59732|Chryseobacterium 976|Bacteroidetes S Secreted repeat of unknown function - - - - - - - - - - - - Lipoprotein_15 k141_19495_1 555778.Hneap_0174 2.57e-14 74.7 COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria,1WYF2@135613|Chromatiales 135613|Chromatiales P Phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P k141_19495_2 1120977.JHUX01000003_gene1566 1.09e-15 73.2 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,3NKT2@468|Moraxellaceae 1236|Gammaproteobacteria G Peptidyl-prolyl cis-trans slyD GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_15231_1 396588.Tgr7_2464 3.29e-76 239.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_15231_2 582744.Msip34_1562 6.33e-69 213.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria,2KMP8@206350|Nitrosomonadales 206350|Nitrosomonadales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_20847_1 1123399.AQVE01000035_gene3167 2.85e-57 184.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,462II@72273|Thiotrichales 72273|Thiotrichales T helix_turn_helix, Lux Regulon - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_20847_2 765910.MARPU_07560 2.97e-05 47.8 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1WWX3@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3 k141_6823_2 1123053.AUDG01000020_gene557 8.19e-27 106.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1WWMU@135613|Chromatiales 135613|Chromatiales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_2759_1 1278309.KB907099_gene3055 1.45e-116 338.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XHW2@135619|Oceanospirillales 135619|Oceanospirillales I enoyl-CoA hydratase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_9023_1 314264.ROS217_04410 2.93e-45 159.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,46P1H@74030|Roseovarius 28211|Alphaproteobacteria E COG0498 Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N k141_9023_2 391593.RCCS2_05354 1.58e-12 66.6 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,2P2FI@2433|Roseobacter 28211|Alphaproteobacteria S Belongs to the peptidase M16 family mpp - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k141_14558_1 1278309.KB907100_gene2177 4.67e-175 521.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIXK@135619|Oceanospirillales 135619|Oceanospirillales C COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits - - - - - - - - - - - - POR k141_18802_1 1354303.M917_1457 1.05e-73 231.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,3NIWW@468|Moraxellaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB GO:0000166,GO:0003674,GO:0005215,GO:0005315,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008144,GO:0008150,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0017076,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035303,GO:0035435,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_7654_1 1285586.H131_15833 6.88e-55 176.0 2DZGK@1|root,32VA1@2|Bacteria,1VWEM@1239|Firmicutes,4HWQM@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k141_20848_1 467661.RKLH11_2717 7.2e-93 276.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,3ZGJV@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_20066_1 1288826.MSNKSG1_15147 1.79e-205 601.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4667H@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_7,TPR_8 k141_20066_4 1288826.MSNKSG1_15132 1.31e-73 221.0 2EBSF@1|root,335SA@2|Bacteria,1NC8T@1224|Proteobacteria,1SE66@1236|Gammaproteobacteria,46CBG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20066_5 1288826.MSNKSG1_15127 0.0 874.0 COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RR1C@1236|Gammaproteobacteria,466VR@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_20066_6 1288826.MSNKSG1_15122 4.45e-276 758.0 COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T1UD@1236|Gammaproteobacteria,46A7X@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1 k141_20066_7 1288826.MSNKSG1_15117 1.61e-94 277.0 COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,466UK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_20066_8 1288826.MSNKSG1_15112 3.99e-28 111.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,464R6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_9024_1 1198452.Jab_2c22570 3.52e-09 60.8 2C5QS@1|root,2ZK8N@2|Bacteria,1RCN2@1224|Proteobacteria,2VRH4@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_2760_1 272942.RCAP_rcc00414 6.5e-11 59.7 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,1FBYG@1060|Rhodobacter 28211|Alphaproteobacteria S Protein of unknown function (DUF1178) MA20_39715 - - - - - - - - - - - DUF1178 k141_2760_2 349102.Rsph17025_3104 9.44e-49 161.0 COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,1FBW1@1060|Rhodobacter 28211|Alphaproteobacteria S PFAM GcrA cell cycle regulator gcrA - - ko:K13583 ko04112,map04112 - - - ko00000,ko00001 - - - GcrA k141_6824_1 1120970.AUBZ01000007_gene2969 4.8e-10 62.0 COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,1RQ1E@1236|Gammaproteobacteria,465EK@72275|Alteromonadaceae 1236|Gammaproteobacteria T GHKL domain nifL - - - - - - - - - - - HATPase_c,PAS,PAS_8,PAS_9 k141_6824_2 1249627.D779_3662 1.15e-38 144.0 COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1WX1Q@135613|Chromatiales 135613|Chromatiales KT Fis Family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,Sigma54_activat k141_6252_1 187272.Mlg_2112 5.21e-29 109.0 COG0824@1|root,COG0824@2|Bacteria,1PUGZ@1224|Proteobacteria,1TAK0@1236|Gammaproteobacteria,1X21V@135613|Chromatiales 135613|Chromatiales S Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_2 k141_20849_1 653733.Selin_0426 5.97e-35 130.0 COG1560@1|root,COG1560@2|Bacteria 2|Bacteria M Kdo2-lipid A biosynthetic process htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_14560_1 391595.RLO149_c015640 5.51e-96 302.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,2P4PJ@2433|Roseobacter 28211|Alphaproteobacteria F Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_20067_1 522306.CAP2UW1_2350 1.5e-44 160.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,2VNUH@28216|Betaproteobacteria 28216|Betaproteobacteria S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_18804_1 686340.Metal_1832 1.93e-78 261.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_2051_1 1278309.KB907100_gene1801 9.35e-77 234.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1XH6N@135619|Oceanospirillales 135619|Oceanospirillales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_16052_1 132113.XP_003493094.1 5.69e-50 176.0 COG0441@1|root,KOG1637@2759|Eukaryota,38C5Y@33154|Opisthokonta,3B9Y5@33208|Metazoa,3CVGA@33213|Bilateria,41Y9F@6656|Arthropoda,3SHCA@50557|Insecta,46JC6@7399|Hymenoptera 33208|Metazoa J Threonyl and Alanyl tRNA synthetase second additional domain - - - - - - - - - - - - HGTP_anticodon,IF3_C,IF3_N,TGS,tRNA-synt_2b,tRNA_SAD k141_16052_2 1049564.TevJSym_ad00070 1.24e-97 303.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1J4XI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_20942_1 999141.GME_14033 1.7e-61 198.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XHUS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_7703_1 1278309.KB907102_gene101 1.94e-28 108.0 COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1S14J@1236|Gammaproteobacteria,1XHGS@135619|Oceanospirillales 135619|Oceanospirillales S Tim44 - - - - - - - - - - - - Tim44 k141_7703_2 1278309.KB907102_gene102 5.3e-110 321.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1XIA7@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0246 family - - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_9085_1 243233.MCA0877 9.55e-63 196.0 COG0847@1|root,COG0847@2|Bacteria,1RDF2@1224|Proteobacteria,1S44N@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exonuclease - - - - - - - - - - - - - k141_9085_2 1026882.MAMP_01511 2.6e-15 72.0 2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,462RV@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_12575_1 498211.CJA_1883 7.67e-45 160.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1FI1N@10|Cellvibrio 1236|Gammaproteobacteria G Glycosyl hydrolase family 57 - - - - - - - - - - - - Glyco_hydro_57 k141_12575_2 1283300.ATXB01000001_gene993 2.75e-32 125.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XDQU@135618|Methylococcales 135618|Methylococcales G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_5602_1 85643.Tmz1t_1320 1.33e-42 150.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VMPX@28216|Betaproteobacteria,2KUUF@206389|Rhodocyclales 206389|Rhodocyclales H Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_5602_2 757424.Hsero_0624 1.12e-44 153.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2VRAI@28216|Betaproteobacteria,477IR@75682|Oxalobacteraceae 28216|Betaproteobacteria NT chemotaxis signal transduction protein cheW3 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_5602_3 765913.ThidrDRAFT_0220 4.6e-31 135.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WX3E@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - - - - - - - - - - 4HB_MCP_1,HAMP,MCPsignal k141_5602_4 644801.Psest_0657 8.6e-201 587.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1Z2IW@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NT Signal transducing histidine kinase, homodimeric domain cheA3 - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_4904_1 102125.Xen7305DRAFT_00051520 3.81e-37 129.0 COG1186@1|root,COG1186@2|Bacteria,1G5Y2@1117|Cyanobacteria,3VJSP@52604|Pleurocapsales 1117|Cyanobacteria J RF-1 domain - - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_18144_1 338969.Rfer_3496 1.82e-107 318.0 28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria,4AGW7@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_14674_1 1260251.SPISAL_06875 1.65e-67 207.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1WYVR@135613|Chromatiales 135613|Chromatiales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ k141_10477_1 1116472.MGMO_171c00150 1.48e-49 182.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XDPM@135618|Methylococcales 135618|Methylococcales T Signal transduction histidine kinase, phosphotransfer (Hpt) region - - - ko:K13490 ko02020,ko02025,map02020,map02025 M00509 - - ko00000,ko00001,ko00002,ko01001,ko02022 - - - CheW,HATPase_c,Hpt,Response_reg k141_2116_1 243233.MCA2269 9e-109 325.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1XF7G@135618|Methylococcales 135618|Methylococcales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_11190_1 1288826.MSNKSG1_10368 2.47e-89 266.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,1S3X9@1236|Gammaproteobacteria,467AY@72275|Alteromonadaceae 1236|Gammaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k141_11190_2 1288826.MSNKSG1_10353 3.73e-123 359.0 COG2207@1|root,COG2207@2|Bacteria,1R6AG@1224|Proteobacteria,1RXY3@1236|Gammaproteobacteria,469VC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_13279_1 637389.Acaty_c0927 3.09e-53 173.0 COG1051@1|root,COG1051@2|Bacteria,1RC3I@1224|Proteobacteria,1S34Y@1236|Gammaproteobacteria,2NDSB@225057|Acidithiobacillales 225057|Acidithiobacillales F NUDIX domain - - - - - - - - - - - - NUDIX k141_20252_1 1286106.MPL1_04045 9.19e-50 166.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,4624P@72273|Thiotrichales 72273|Thiotrichales P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_20252_2 754476.Q7A_2453 7.38e-36 129.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,460JQ@72273|Thiotrichales 72273|Thiotrichales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_20943_2 314278.NB231_06950 5.53e-30 122.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales 135613|Chromatiales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_13972_1 1288826.MSNKSG1_17441 7.69e-164 467.0 COG2067@1|root,COG2067@2|Bacteria,1RA6W@1224|Proteobacteria,1RPD8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X k141_9781_2 1223521.BBJX01000002_gene2710 5.47e-76 251.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MUAK@1224|Proteobacteria,2VIS3@28216|Betaproteobacteria,4ACJ3@80864|Comamonadaceae 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_8396_2 391615.ABSJ01000022_gene341 0.0 906.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4RW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DNA helicase uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_10478_1 396588.Tgr7_0038 7.97e-74 237.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_17442_1 1288826.MSNKSG1_13807 3.41e-314 872.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,4657E@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases fadE - 1.3.8.7 ko:K00249,ko:K06445 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_17442_2 1288826.MSNKSG1_13802 2.28e-179 503.0 COG1575@1|root,COG1575@2|Bacteria,1QQSG@1224|Proteobacteria,1RTFR@1236|Gammaproteobacteria,467N6@72275|Alteromonadaceae 1236|Gammaproteobacteria H Prenyltransferase menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_17442_3 1288826.MSNKSG1_13797 1.79e-196 547.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,468IU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_17442_4 1288826.MSNKSG1_13792 4.91e-265 728.0 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,464DS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K00842,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_17442_5 1288826.MSNKSG1_13787 1.69e-205 570.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,467G1@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_17442_6 1288826.MSNKSG1_13782 1.43e-257 710.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_17442_7 1288826.MSNKSG1_13777 1.84e-204 584.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464YW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 k141_2812_1 330214.NIDE0473 4.4e-73 233.0 COG4307@1|root,COG4307@2|Bacteria 2|Bacteria T Protein conserved in bacteria - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k141_2812_2 1380391.JIAS01000015_gene111 4.38e-91 283.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,2U1M9@28211|Alphaproteobacteria,2JYEI@204441|Rhodospirillales 204441|Rhodospirillales M ATP-grasp domain - - - - - - - - - - - - Dala_Dala_lig_C k141_2812_3 1415780.JPOG01000001_gene525 3.87e-37 130.0 2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria,1XAMU@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_2812_4 1049564.TevJSym_an00240 2.23e-201 573.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1J4RN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,STAS_2,Sulfate_transp k141_4203_2 754476.Q7A_2416 5.16e-76 234.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_4203_3 391615.ABSJ01000038_gene406 3e-12 71.2 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,1J6Y2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - k141_4203_4 717773.Thicy_0276 5.98e-56 182.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,46143@72273|Thiotrichales 72273|Thiotrichales S membrane transporter protein - - - ko:K07090,ko:K11312 - - - - ko00000 - - - TauE k141_6292_1 1278309.KB907101_gene530 9.97e-56 193.0 COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria,1T1HY@1236|Gammaproteobacteria,1XRY3@135619|Oceanospirillales 135619|Oceanospirillales S Oxygen tolerance - - - - - - - - - - - - BatD k141_6292_2 1278309.KB907101_gene529 1.58e-159 453.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XH5V@135619|Oceanospirillales 135619|Oceanospirillales S nucleoside-diphosphate sugar epimerase - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_6292_3 1278309.KB907101_gene528 7.1e-124 355.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XJT5@135619|Oceanospirillales 135619|Oceanospirillales H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_6292_4 1278309.KB907101_gene527 9.05e-88 275.0 COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIHK@135619|Oceanospirillales 135619|Oceanospirillales C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - Fer4_10,POR_N,TPP_enzyme_C k141_21630_1 1278309.KB907100_gene1787 4.39e-34 126.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,1XJMD@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_21630_2 690585.JNNU01000035_gene4003 3.69e-215 599.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,4B78X@82115|Rhizobiaceae 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_735_1 1238450.VIBNISOn1_1400007 6.92e-48 165.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XSYN@135623|Vibrionales 135623|Vibrionales J With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P epmA GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_1419_2 1280953.HOC_09479 1.94e-15 87.8 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,43WMM@69657|Hyphomonadaceae 28211|Alphaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg k141_2117_1 983920.Y88_2510 1.12e-27 104.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales 204457|Sphingomonadales S FeS assembly SUF system protein - - - - - - - - - - - - FeS_assembly_P k141_2117_2 768671.ThimaDRAFT_2141 1.67e-46 152.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1WYM7@135613|Chromatiales 135613|Chromatiales S Belongs to the HesB IscA family - - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_12577_1 1249627.D779_3815 5.81e-120 361.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales 135613|Chromatiales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_4905_1 589865.DaAHT2_1412 1.45e-92 288.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2MIA7@213118|Desulfobacterales 28221|Deltaproteobacteria M TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase - - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_20253_2 1122604.JONR01000001_gene1738 1.04e-64 211.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_10479_1 367336.OM2255_12577 2.14e-82 253.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_11192_1 396588.Tgr7_2333 2.2e-81 245.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1WXDE@135613|Chromatiales 135613|Chromatiales J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_18857_1 204669.Acid345_4235 0.000293 47.8 COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria,2JKYI@204432|Acidobacteriia 204432|Acidobacteriia KLT Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_18857_2 1121935.AQXX01000132_gene2676 1.08e-19 87.4 COG5000@1|root,COG5000@2|Bacteria,1R45S@1224|Proteobacteria,1RY7Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365,HAMP k141_14675_1 90814.KL370891_gene1377 8.51e-76 240.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2,Usp k141_14675_2 1123514.KB905899_gene1989 6.67e-124 370.0 COG0531@1|root,COG0531@2|Bacteria,1PKIV@1224|Proteobacteria,1T9HU@1236|Gammaproteobacteria,461MJ@72273|Thiotrichales 72273|Thiotrichales E Amino acid permease - - - - - - - - - - - - AA_permease_2 k141_3516_1 1283284.AZUK01000001_gene1364 4.61e-10 58.9 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1Y4EK@135624|Aeromonadales 135624|Aeromonadales L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle - - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_3516_2 754476.Q7A_1272 7.41e-47 154.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,460XS@72273|Thiotrichales 72273|Thiotrichales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_7009_1 1288826.MSNKSG1_11433 9.08e-238 671.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,468WP@72275|Alteromonadaceae 1236|Gammaproteobacteria I membrane-associated protein lssY - - ko:K03975 - - - - ko00000 - - - LssY_C,PAP2,SNARE_assoc k141_7009_2 1288826.MSNKSG1_11438 1.78e-56 186.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,1RNP5@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_21631_1 580332.Slit_2116 1.86e-63 202.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales 28216|Betaproteobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_7028_1 1278309.KB907101_gene280 7.76e-200 573.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_746_1 1636182.A0A0F6R5W6_9CAUD 2.7e-18 85.5 4QH2M@10239|Viruses,4QSTN@28883|Caudovirales 28883|Caudovirales S Trypsin-like peptidase domain - - - - - - - - - - - - - k141_2826_1 314278.NB231_15223 5.09e-121 379.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_14700_1 697282.Mettu_2394 1.3e-11 59.7 COG1977@1|root,COG1977@2|Bacteria,1NHG7@1224|Proteobacteria,1TG6J@1236|Gammaproteobacteria,1XFT3@135618|Methylococcales 135618|Methylococcales H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_14700_2 857087.Metme_0536 2.56e-56 180.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1XFC1@135618|Methylococcales 135618|Methylococcales H MoaE protein moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE k141_9802_1 270374.MELB17_12071 1.89e-82 254.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,465NH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_3523_2 666685.R2APBS1_0866 4.95e-43 145.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X6S4@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis signal transduction protein - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_20977_2 1123514.KB905899_gene1284 1.59e-09 60.5 2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,1SEPF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20977_3 765912.Thimo_1325 4.4e-45 153.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1WXHT@135613|Chromatiales 135613|Chromatiales I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_18167_1 1278309.KB907105_gene1419 8.27e-210 601.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_11218_1 1226325.HMPREF1548_00720 3.09e-64 211.0 COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,36DKE@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 k141_19561_1 1278309.KB907099_gene2746 2.97e-123 366.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XICX@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_13982_1 1123400.KB904767_gene3416 2.48e-58 195.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,45ZUG@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_13982_2 1177179.A11A3_11252 1.88e-19 85.5 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria,1XNB9@135619|Oceanospirillales 135619|Oceanospirillales L 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k141_9108_1 571166.KI421509_gene4161 1.02e-96 299.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily sulP - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_8407_1 1448139.AI20_01610 3.19e-133 391.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1Y3XB@135624|Aeromonadales 135624|Aeromonadales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_8407_2 472759.Nhal_2361 4.4e-12 68.6 2952G@1|root,2ZSF9@2|Bacteria,1NFKJ@1224|Proteobacteria,1SDRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8407_3 555778.Hneap_0507 1.27e-09 59.7 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales 135613|Chromatiales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_5838_4 1288826.MSNKSG1_15002 1.3e-166 469.0 COG1184@1|root,COG1184@2|Bacteria,1QR0G@1224|Proteobacteria,1RTRZ@1236|Gammaproteobacteria,46C10@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the eIF-2B alpha beta delta subunits family - - - - - - - - - - - - IF-2B k141_5838_5 1288826.MSNKSG1_14997 6.05e-98 306.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,46421@72275|Alteromonadaceae 1236|Gammaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_20472_1 1121918.ARWE01000001_gene2831 8.25e-89 265.0 COG2755@1|root,COG2755@2|Bacteria,1RDVJ@1224|Proteobacteria 1224|Proteobacteria E lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_9237_1 999549.KI421513_gene2804 8.23e-141 402.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2818K@191028|Leisingera 28211|Alphaproteobacteria H Thiazole biosynthesis protein ThiG thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG,ThiS k141_9237_2 348824.LPU83_4036 3.56e-07 50.4 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2TSXT@28211|Alphaproteobacteria,4BB7J@82115|Rhizobiaceae 28211|Alphaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_12787_1 257310.BB3232 7.97e-17 92.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,3T1VD@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function - - - - - - - - - - - - AsmA_2,DUF3971 k141_15581_1 1208323.B30_08438 5.47e-56 185.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_15581_2 1122614.JHZF01000011_gene1603 3.59e-40 141.0 COG4665@1|root,COG4665@2|Bacteria,1MVFC@1224|Proteobacteria,2TTID@28211|Alphaproteobacteria,2PDCU@252301|Oceanicola 28211|Alphaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_14876_1 1288826.MSNKSG1_04896 8.74e-18 79.3 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,465SG@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_14876_2 1288826.MSNKSG1_04901 0.0 1108.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,46570@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_21822_1 1288826.MSNKSG1_02033 2.95e-47 160.0 COG0697@1|root,COG0697@2|Bacteria,1R6CU@1224|Proteobacteria,1SZQJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_21822_2 1288826.MSNKSG1_02038 6.12e-200 555.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1SZJQ@1236|Gammaproteobacteria,467NX@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_21822_3 439496.RBY4I_2409 5.49e-74 232.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TUVG@28211|Alphaproteobacteria 28211|Alphaproteobacteria C alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_17653_1 1288826.MSNKSG1_16231 7.2e-196 560.0 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,46A57@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CZB,EAL,GAF_2,GGDEF,Hemerythrin,PAS_4,PAS_9,Protoglobin k141_2276_1 1288826.MSNKSG1_09753 2.09e-93 281.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,4648M@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_2276_2 1288826.MSNKSG1_09748 5e-169 473.0 COG1296@1|root,COG1296@2|Bacteria,1Q43G@1224|Proteobacteria,1RPZB@1236|Gammaproteobacteria,4673N@72275|Alteromonadaceae 1236|Gammaproteobacteria E branched-chain amino acid permease (azaleucine resistance) - - - - - - - - - - - - AzlC k141_2276_3 1288826.MSNKSG1_09743 7.34e-55 172.0 COG4541@1|root,COG4541@2|Bacteria,1NDCP@1224|Proteobacteria,1SF44@1236|Gammaproteobacteria,468TU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Branched-chain amino acid transport protein (AzlD) - - - - - - - - - - - - AzlD k141_2276_4 1288826.MSNKSG1_09738 5.94e-182 506.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,1RP35@1236|Gammaproteobacteria,4671K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 k141_2276_5 1288826.MSNKSG1_09733 8.46e-32 111.0 COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria,46BR1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin k141_4416_1 1278309.KB907099_gene2487 1.14e-69 213.0 COG0226@1|root,COG0226@2|Bacteria,1N19C@1224|Proteobacteria,1SEQX@1236|Gammaproteobacteria,1XM1Q@135619|Oceanospirillales 135619|Oceanospirillales P COG0226 ABC-type phosphate transport system, periplasmic component - - - - - - - - - - - - - k141_4416_2 1278309.KB907099_gene2488 1.49e-212 596.0 COG3203@1|root,COG3203@2|Bacteria,1PJNW@1224|Proteobacteria,1RZXJ@1236|Gammaproteobacteria,1XIW3@135619|Oceanospirillales 135619|Oceanospirillales M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k141_4416_3 1278309.KB907099_gene2489 4.84e-125 384.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XISY@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,Response_reg k141_7177_1 644107.SL1157_2703 3.45e-96 285.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria,4NBEU@97050|Ruegeria 28211|Alphaproteobacteria Q DSBA-like thioredoxin domain dsb - - - - - - - - - - - DSBA k141_20486_1 1123514.KB905899_gene1175 7.51e-208 592.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,4603S@72273|Thiotrichales 72273|Thiotrichales KLT Serine/threonine phosphatases, family 2C, catalytic domain - - - - - - - - - - - - PP2C_2,Pkinase k141_20486_2 1333856.L686_02440 2.19e-133 382.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1Z0BE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG2116 Formate nitrite family of transporters fnt - - ko:K06212,ko:K21993 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 - - Form_Nir_trans k141_13486_2 1415779.JOMH01000001_gene1769 1.33e-67 224.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,1X4IW@135614|Xanthomonadales 135614|Xanthomonadales S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_18367_1 1134474.O59_000070 1.5e-135 391.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K07506,ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_18367_2 697282.Mettu_1366 1.76e-72 223.0 2E7KN@1|root,3322N@2|Bacteria,1N6FH@1224|Proteobacteria,1SSF1@1236|Gammaproteobacteria,1XF9V@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF1097) - - - - - - - - - - - - DUF1097 k141_18367_3 1122165.AUHS01000018_gene1949 2.1e-19 93.2 COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S0P0@1236|Gammaproteobacteria,1JE1Z@118969|Legionellales 118969|Legionellales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GGDEF,PAS,PAS_3 k141_3736_2 754477.Q7C_1700 8.48e-29 105.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,461HK@72273|Thiotrichales 72273|Thiotrichales G TIGRFAM Phosphotransferase System HPr (HPr) Family - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_3736_3 1279019.ARQK01000047_gene1060 2.5e-27 103.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1WYYD@135613|Chromatiales 135613|Chromatiales G system, fructose subfamily IIA component - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man k141_7201_1 1026882.MAMP_03147 9.22e-73 228.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,460GA@72273|Thiotrichales 72273|Thiotrichales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_16963_1 1049564.TevJSym_av00060 1.92e-18 77.4 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1J6XM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 k141_16963_3 1276756.AUEX01000003_gene662 1.58e-50 177.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,4AB63@80864|Comamonadaceae 28216|Betaproteobacteria F thymidine phosphorylase - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_16236_1 472759.Nhal_1910 2.75e-26 109.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,1WWAF@135613|Chromatiales 135613|Chromatiales V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_16236_2 1485545.JQLW01000005_gene1026 9.41e-49 163.0 2DMDY@1|root,32QU6@2|Bacteria 2|Bacteria S Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_14183_1 1288826.MSNKSG1_06253 4.17e-62 195.0 2E5SG@1|root,330GY@2|Bacteria,1NB2M@1224|Proteobacteria,1SCUK@1236|Gammaproteobacteria,468X9@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14183_2 1288826.MSNKSG1_06258 1.16e-200 555.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,465AT@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0708 Exonuclease III xthA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_14183_3 1288826.MSNKSG1_06263 4.72e-96 283.0 COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,1S6PU@1236|Gammaproteobacteria,46DGN@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR,TetR_N k141_918_1 1123277.KB893180_gene2464 2.88e-13 68.9 COG5485@1|root,COG5485@2|Bacteria,4NQC7@976|Bacteroidetes,47SS5@768503|Cytophagia 976|Bacteroidetes S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL k141_918_2 1217715.F994_03291 4.06e-16 77.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S69Q@1236|Gammaproteobacteria,3NNBK@468|Moraxellaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_918_3 1288826.MSNKSG1_14207 7.83e-174 489.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,46786@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rhodanese Homology Domain sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_13487_1 381666.PHG233 4.77e-19 86.3 COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2VUY4@28216|Betaproteobacteria,1K7DB@119060|Burkholderiaceae 28216|Betaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_9261_1 1279015.KB908456_gene1611 1.35e-92 286.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1Y3UB@135624|Aeromonadales 135624|Aeromonadales O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_7935_1 1337093.MBE-LCI_3398 2.2e-121 354.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_2284_2 743299.Acife_1795 8.22e-83 259.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,2NCGY@225057|Acidithiobacillales 225057|Acidithiobacillales GM Saccharopine dehydrogenase NADP binding domain - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 k141_9945_1 3055.EDP07358 7.51e-39 145.0 COG0320@1|root,KOG2672@2759|Eukaryota,37PYM@33090|Viridiplantae,34J3R@3041|Chlorophyta 3041|Chlorophyta H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives LIP1P GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_9945_2 998088.B565_1477 5.09e-61 198.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1Y5HX@135624|Aeromonadales 135624|Aeromonadales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_214_1 1049564.TevJSym_ah00980 7.86e-133 389.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1J51T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_214_2 1286106.MPL1_10127 7.37e-49 167.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,45ZWB@72273|Thiotrichales 72273|Thiotrichales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_17674_1 439496.RBY4I_206 7.1e-89 275.0 COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the aldehyde dehydrogenase family alh GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_15591_1 927677.ALVU02000001_gene1332 1.31e-26 107.0 COG0492@1|root,COG0492@2|Bacteria,1G082@1117|Cyanobacteria,1H612@1142|Synechocystis 1117|Cyanobacteria O Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_15591_3 586413.CCDL010000004_gene3399 9.34e-09 59.3 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,23KH9@182709|Oceanobacillus 91061|Bacilli CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_11410_1 1049564.TevJSym_aj00050 6.67e-68 213.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,1J92F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20487_1 1305737.JAFX01000001_gene2281 3.14e-88 272.0 COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia 976|Bacteroidetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k141_3737_1 765911.Thivi_2691 1.81e-10 58.5 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,1WYQN@135613|Chromatiales 135613|Chromatiales S Probably plays a role in a hydrogenase nickel cofactor insertion step hypA - - ko:K04651 - - - - ko00000,ko03110 - - - HypA k141_3737_2 292415.Tbd_1381 8.62e-33 115.0 COG0298@1|root,COG0298@2|Bacteria,1PWRZ@1224|Proteobacteria,2WCAT@28216|Betaproteobacteria,1KTC5@119069|Hydrogenophilales 119069|Hydrogenophilales O HupF/HypC family - - - ko:K04653 - - - - ko00000 - - - HupF_HypC k141_7202_1 1288826.MSNKSG1_07498 2.38e-63 193.0 COG2329@1|root,COG2329@2|Bacteria,1N861@1224|Proteobacteria,1SC9H@1236|Gammaproteobacteria,468QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_7202_2 1288826.MSNKSG1_07493 1.05e-52 165.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,468CY@72275|Alteromonadaceae 1236|Gammaproteobacteria O Sulfur carrier protein which probably makes part of a sulfur-relay system tusA GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_18368_1 765913.ThidrDRAFT_0704 1.4e-30 124.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1WX5R@135613|Chromatiales 135613|Chromatiales I aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_12101_1 1278309.KB907101_gene783 8.01e-189 529.0 COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria,1T1C8@1236|Gammaproteobacteria,1XRRK@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III, delta subunit, C terminal - - - - - - - - - - - - DNA_pol3_delta2,DNApol3-delta_C k141_12101_2 1278309.KB907101_gene782 2.2e-122 352.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1XJCZ@135619|Oceanospirillales 135619|Oceanospirillales F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin k141_12101_3 1278309.KB907101_gene781 1.52e-189 533.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1XH57@135619|Oceanospirillales 135619|Oceanospirillales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_12101_4 472759.Nhal_3120 2.2e-70 225.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_12101_5 1122201.AUAZ01000017_gene2910 1.01e-106 318.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,463YA@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Ketoacyl-synt_C,ketoacyl-synt k141_11411_1 1485545.JQLW01000006_gene297 1.3e-82 268.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria 1224|Proteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_7936_1 1288826.MSNKSG1_14242 3.81e-34 126.0 COG0477@1|root,COG2814@2|Bacteria,1MVTM@1224|Proteobacteria,1RR5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_7936_2 1288826.MSNKSG1_14217 3.49e-87 256.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,467D7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_4446_1 765914.ThisiDRAFT_1466 9.89e-32 119.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1WY2F@135613|Chromatiales 135613|Chromatiales O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_4446_2 1260251.SPISAL_04555 8.48e-86 266.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales 135613|Chromatiales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_9262_1 998674.ATTE01000001_gene3728 2.08e-125 384.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales 72273|Thiotrichales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_16965_1 1127131.WEISSC39_07745 0.000636 45.4 COG1388@1|root,COG1388@2|Bacteria,1VBZ7@1239|Firmicutes,4HMHB@91061|Bacilli 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM k141_216_1 375451.RD1_3809 4.84e-86 260.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TTVF@28211|Alphaproteobacteria,2P2MC@2433|Roseobacter 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gno - 1.1.1.127,1.1.1.69 ko:K00046,ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_919_1 391165.GbCGDNIH1_1520 1.65e-08 55.1 28I8U@1|root,2Z8BM@2|Bacteria,1R8BF@1224|Proteobacteria,2UB4M@28211|Alphaproteobacteria,2JXYZ@204441|Rhodospirillales 204441|Rhodospirillales S Beta protein - - - - - - - - - - - - Beta_protein k141_919_2 318586.Pden_0443 3.26e-41 143.0 COG2856@1|root,COG2856@2|Bacteria,1PCST@1224|Proteobacteria,2V5N5@28211|Alphaproteobacteria,2PZ0D@265|Paracoccus 28211|Alphaproteobacteria E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 k141_919_3 1219065.VPR01S_04_02330 5.59e-30 114.0 2DDQ1@1|root,2ZIV7@2|Bacteria,1PASD@1224|Proteobacteria,1STYK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9946_1 1122194.AUHU01000003_gene2291 1.61e-233 650.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,464MV@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria impC - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_2286_1 596151.DesfrDRAFT_1503 1.94e-18 82.4 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2WRIP@28221|Deltaproteobacteria,2MBC0@213115|Desulfovibrionales 28221|Deltaproteobacteria M pfam nlp p60 - - - - - - - - - - - - NLPC_P60,SPOR k141_7937_2 1158756.AQXQ01000012_gene1345 3.65e-10 62.4 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWSZ@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_16966_1 1333856.L686_01035 3.81e-43 158.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1Z0AH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_20489_1 658187.LDG_7706 6.86e-57 185.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1JDQH@118969|Legionellales 118969|Legionellales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_16237_1 502025.Hoch_5635 5.38e-112 352.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria,2YU6A@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_1764_6 1288826.MSNKSG1_12982 1.22e-189 528.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,464HW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB GO:0000166,GO:0003674,GO:0005215,GO:0005315,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008144,GO:0008150,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0017076,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035303,GO:0035435,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_1764_7 1288826.MSNKSG1_12987 6.85e-173 485.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,46B73@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 BPD_transp_1 k141_1764_8 1288826.MSNKSG1_12992 7.38e-212 587.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,46B68@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component pstC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - ic_1306.c4652 BPD_transp_1 k141_1764_9 1288826.MSNKSG1_12997 4.25e-248 681.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria,46AVT@72275|Alteromonadaceae 1236|Gammaproteobacteria P PBP superfamily domain pstS GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - iECH74115_1262.ECH74115_5157,iECSP_1301.ECSP_4770,iECs_1301.ECs4664,iG2583_1286.G2583_4518,iJN746.PP_2656,iZ_1308.Z5219 PBP_like_2 k141_1764_10 1288826.MSNKSG1_13002 4.3e-157 442.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,466D2@72275|Alteromonadaceae 1236|Gammaproteobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU k141_1764_11 1288826.MSNKSG1_13007 8.22e-91 266.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,467IG@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1607 Acyl-CoA hydrolase yciA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT k141_1764_12 1288826.MSNKSG1_13012 5.66e-73 227.0 COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,46AM8@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_12914_1 391589.RGAI101_3053 3.13e-92 282.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2P1XQ@2433|Roseobacter 28211|Alphaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_5205_1 1454004.AW11_02765 2.7e-93 290.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase cpxA - 2.7.13.3 ko:K02484,ko:K07640,ko:K07642 ko01503,ko02020,map01503,map02020 M00447,M00450,M00645,M00646,M00648,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_12221_1 105559.Nwat_0447 1.12e-107 326.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales 135613|Chromatiales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_10827_1 324602.Caur_2921 1.97e-66 215.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity marMP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_4556_1 391616.OA238_c14520 4.58e-48 162.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TT59@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_4556_2 384765.SIAM614_07713 2.54e-87 266.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U0D6@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440,ko:K17206 ko02010,map02010 M00212,M00591 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.15,3.A.1.2.19 - - BPD_transp_2 k141_6578_1 1121035.AUCH01000001_gene2048 1.55e-21 92.8 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2WHAV@28216|Betaproteobacteria 28216|Betaproteobacteria Q Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_6578_2 760117.JN27_15605 0.000459 46.2 COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,2VM6H@28216|Betaproteobacteria,475PA@75682|Oxalobacteraceae 28216|Betaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_19215_1 1278309.KB907101_gene760 2.29e-100 300.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RNZB@1236|Gammaproteobacteria,1XR9N@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - ko:K17737 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_17795_1 323261.Noc_2040 8.03e-88 269.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1WVZU@135613|Chromatiales 135613|Chromatiales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_3176_1 1288826.MSNKSG1_17655 1.37e-112 331.0 2F1ZF@1|root,33UYR@2|Bacteria,1NVFQ@1224|Proteobacteria,1SQGG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3176_2 1288826.MSNKSG1_17660 1.93e-116 335.0 2E201@1|root,32X8B@2|Bacteria,1N5AJ@1224|Proteobacteria,1SAHZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3176_3 1288826.MSNKSG1_17665 7.6e-79 254.0 2DBQU@1|root,2ZAGT@2|Bacteria,1R53U@1224|Proteobacteria,1RZUC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13583_1 349521.HCH_00752 6.02e-230 649.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate transport system permease protein - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_19846_1 1267533.KB906738_gene2257 2.36e-05 49.7 COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia 204432|Acidobacteriia U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_10828_1 266265.Bxe_A1390 3.21e-12 66.2 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,1JZSR@119060|Burkholderiaceae 28216|Betaproteobacteria C acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_10828_2 1122137.AQXF01000001_gene2641 3.31e-27 111.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TSKH@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_5928_1 1415778.JQMM01000001_gene904 3.89e-19 83.6 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1J72N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG3030 Protein affecting phage T7 exclusion by the F plasmid fxsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K07113 - - - - ko00000 - - - FxsA k141_5928_2 3750.XP_008357552.1 5.63e-27 104.0 COG1324@1|root,KOG3338@2759|Eukaryota,37Q9K@33090|Viridiplantae,3GBI0@35493|Streptophyta,4JNWT@91835|fabids 35493|Streptophyta P Protein CutA, chloroplastic-like - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - ko:K03926 - - - - ko00000 - - - CutA1 k141_12915_1 103733.JNYO01000022_gene6881 7.37e-56 203.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_19216_1 641524.ADICYQ_0810 1.48e-60 193.0 COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,47KMH@768503|Cytophagia 976|Bacteroidetes K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_364_1 572477.Alvin_0632 1.11e-300 829.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_12222_1 7668.SPU_019910-tr 3.4e-16 85.1 2CXRP@1|root,2RZ9M@2759|Eukaryota,3A84X@33154|Opisthokonta,3BTAV@33208|Metazoa,3DA4U@33213|Bilateria 33208|Metazoa S DDE superfamily endonuclease - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - - - - - - - - - - DDE_3,HTH_38,HTH_Tnp_Tc3_1,HTH_Tnp_Tc3_2 k141_3830_1 89187.ISM_06680 6.81e-150 450.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,46PGN@74030|Roseovarius 28211|Alphaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_5207_1 395493.BegalDRAFT_1677 2.48e-80 261.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent Clp protease ATP-binding subunit ClpA - - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_17796_1 338969.Rfer_2240 4.61e-61 199.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2VJI6@28216|Betaproteobacteria,4AAH2@80864|Comamonadaceae 28216|Betaproteobacteria F Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_10829_1 90813.JQMT01000001_gene1064 1.19e-103 319.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales 72273|Thiotrichales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_7323_1 177416.FTT_0061 1.54e-11 65.5 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,46125@72273|Thiotrichales 72273|Thiotrichales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_7323_2 1286106.MPL1_12191 1.01e-36 130.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales 72273|Thiotrichales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_7323_3 1123393.KB891332_gene2797 3.96e-38 128.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,1KRWR@119069|Hydrogenophilales 119069|Hydrogenophilales C ATP synthase subunit C - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_1047_1 314278.NB231_15223 8.8e-212 624.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_12916_1 580332.Slit_1782 5.24e-51 173.0 COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria 1224|Proteobacteria T response regulator - - - - - - - - - - - - Guanylate_cyc,HATPase_c,HisKA,Response_reg k141_19847_1 314292.VAS14_14659 2.32e-47 160.0 2DZY4@1|root,32VMX@2|Bacteria,1QEQ9@1224|Proteobacteria,1TBIE@1236|Gammaproteobacteria,1Y12C@135623|Vibrionales 135623|Vibrionales S Family of unknown function (DUF695) - - - - - - - - - - - - DUF695 k141_6580_1 472759.Nhal_1052 7.72e-61 192.0 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1WXZH@135613|Chromatiales 135613|Chromatiales G PFAM Phosphoglycerate mutase - - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_17062_1 1121396.KB893120_gene3074 3.15e-36 134.0 COG0019@1|root,COG0019@2|Bacteria,1R4VG@1224|Proteobacteria,42Z5C@68525|delta/epsilon subdivisions,2WUBY@28221|Deltaproteobacteria,2MMY8@213118|Desulfobacterales 28221|Deltaproteobacteria E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_17062_2 1121396.KB893120_gene3073 5.09e-43 147.0 COG2940@1|root,COG2940@2|Bacteria,1RH54@1224|Proteobacteria,42YUT@68525|delta/epsilon subdivisions,2WU8Y@28221|Deltaproteobacteria,2MMK0@213118|Desulfobacterales 28221|Deltaproteobacteria S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - - - - - - - - - - - k141_18452_1 1123360.thalar_01693 1.21e-94 293.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 k141_18452_2 1123360.thalar_01692 1.67e-13 68.9 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_10080_1 465817.ETA_19670 2.18e-52 176.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,3X5NX@551|Erwinia 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_10080_2 225937.HP15_2087 4.82e-61 196.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,467AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S High frequency lysogenization protein HflD homolog hflD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - ko:K07153 - - - - ko00000 - - - DUF489 k141_10080_3 1283300.ATXB01000001_gene1554 5.69e-61 192.0 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria,1XGES@135618|Methylococcales 135618|Methylococcales J ribosomal large subunit export from nucleus - - - - - - - - - - - - - k141_10080_4 870187.Thini_2815 1.07e-87 263.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,45ZW8@72273|Thiotrichales 72273|Thiotrichales O Alkyl hydroperoxide reductase - - - - - - - - - - - - AhpC-TSA k141_10080_5 1269813.ATUL01000002_gene960 0.000194 49.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WWY8@135613|Chromatiales 135613|Chromatiales NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_1767_1 1049564.TevJSym_aj00410 9.87e-104 322.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1J51W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1032 Fe-S oxidoreductase ygiQ - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_1048_1 1123368.AUIS01000029_gene1281 1.6e-124 363.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,2NBS6@225057|Acidithiobacillales 225057|Acidithiobacillales K LysR substrate binding domain - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_21300_1 1288826.MSNKSG1_10703 9.44e-109 317.0 COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,1SASV@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG1651 Protein-disulfide isomerase - - - - - - - - - - - - Thioredoxin_4 k141_21300_2 1288826.MSNKSG1_10708 8.48e-211 584.0 COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,1RTQR@1236|Gammaproteobacteria,4663V@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_15699_1 391626.OAN307_c47350 1.87e-70 223.0 COG1466@1|root,COG1466@2|Bacteria,1R8PA@1224|Proteobacteria,2U1KQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta k141_7325_2 631362.Thi970DRAFT_03146 5.56e-18 82.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1WY72@135613|Chromatiales 135613|Chromatiales O TIGRFAM clan AA aspartic protease, TIGR02281 family - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_17797_1 1049564.TevJSym_ap00240 7.83e-09 52.8 2C7FC@1|root,32S1T@2|Bacteria,1N1DJ@1224|Proteobacteria,1S96F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17797_2 1283300.ATXB01000001_gene42 8.61e-114 344.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RQMD@1236|Gammaproteobacteria,1XGZF@135618|Methylococcales 135618|Methylococcales G Carbohydrate phosphorylase - - - - - - - - - - - - Phosphorylase k141_10081_1 454957.IA64_19085 1.35e-48 167.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X55Q@135614|Xanthomonadales 135614|Xanthomonadales EH component I pabB - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_10081_2 265072.Mfla_1502 3.17e-10 60.5 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2VRAS@28216|Betaproteobacteria,2KMJW@206350|Nitrosomonadales 206350|Nitrosomonadales EH PFAM Aminotransferase class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_17063_1 1353537.TP2_13635 6.37e-103 309.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2XN8D@285107|Thioclava 28211|Alphaproteobacteria G C4-dicarboxylate ABC transporter - - - - - - - - - - - - DctM k141_10831_1 314275.MADE_1012655 5e-45 152.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,467DX@72275|Alteromonadaceae 1236|Gammaproteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_18453_1 272942.RCAP_rcc00129 4.28e-80 249.0 COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,2TQM4@28211|Alphaproteobacteria,1FARN@1060|Rhodobacter 28211|Alphaproteobacteria K periplasmic binding protein LacI transcriptional regulator - - - ko:K06145 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_3831_1 1279017.AQYJ01000029_gene3622 2.05e-48 179.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 k141_13585_1 1122599.AUGR01000006_gene3840 8.22e-87 270.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XNBS@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_13585_2 1122599.AUGR01000006_gene3841 3.69e-179 510.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XIN8@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_16337_1 1278309.KB907102_gene138 0.0 938.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XH42@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D3 k141_16337_2 1278309.KB907102_gene139 1.48e-216 598.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1XH66@135619|Oceanospirillales 135619|Oceanospirillales EH Sulfate adenylyltransferase subunit 2 cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_17076_1 747.DR93_676 1.48e-93 280.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1Y79A@135625|Pasteurellales 135625|Pasteurellales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_17076_2 977880.RALTA_A0386 8.43e-49 159.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,1K72E@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 k141_17076_3 105559.Nwat_2187 7.44e-226 633.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales 135613|Chromatiales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_17076_4 765910.MARPU_15960 2.21e-43 145.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales 135613|Chromatiales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_3201_1 1278309.KB907103_gene1042 2.63e-211 608.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XHR6@135619|Oceanospirillales 135619|Oceanospirillales C Succinyl-CoA ligase like flavodoxin domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_3839_1 391615.ABSJ01000026_gene110 3.39e-68 226.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding k141_12939_1 1278309.KB907102_gene264 4.21e-220 616.0 28KKP@1|root,2ZA5F@2|Bacteria,1PCB9@1224|Proteobacteria,1RPVV@1236|Gammaproteobacteria,1XIQ1@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_12939_2 1278309.KB907102_gene265 2.74e-130 375.0 28I2H@1|root,2Z86K@2|Bacteria,1R7TY@1224|Proteobacteria,1RZP8@1236|Gammaproteobacteria,1XIUN@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4194) - - - - - - - - - - - - DUF4194 k141_12939_3 1278309.KB907102_gene266 1.2e-149 452.0 COG1196@1|root,COG1196@2|Bacteria,1QUTY@1224|Proteobacteria,1T351@1236|Gammaproteobacteria,1XHM7@135619|Oceanospirillales 135619|Oceanospirillales D DNA replication and repair protein RecF - - - - - - - - - - - - AAA_29,SbcCD_C k141_19868_1 1141662.OOA_04582 9.95e-64 212.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,3Z7CK@586|Providencia 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_21994_1 1286632.P278_31760 6.22e-114 345.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia 976|Bacteroidetes J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_11528_1 1443111.JASG01000004_gene798 5.06e-28 112.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,3ZV3Q@60136|Sulfitobacter 28211|Alphaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_10852_1 1415756.JQMY01000001_gene2956 1.33e-36 137.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,2PD2E@252301|Oceanicola 28211|Alphaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10852_2 985054.JQEZ01000001_gene2518 4.77e-09 57.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,4NAFR@97050|Ruegeria 28211|Alphaproteobacteria M Penicillin-binding Protein dimerisation domain ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_20620_1 246197.MXAN_6190 1.64e-22 97.8 COG0591@1|root,COG0591@2|Bacteria,1R4VK@1224|Proteobacteria,42UZA@68525|delta/epsilon subdivisions,2WSQC@28221|Deltaproteobacteria,2YVTZ@29|Myxococcales 28221|Deltaproteobacteria E Sodium:solute symporter family - - - - - - - - - - - - SSF k141_20620_2 1168034.FH5T_01410 6.01e-06 48.5 2EFPT@1|root,339FT@2|Bacteria,4NV1V@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_5239_1 317025.Tcr_2071 1.19e-26 99.4 COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,4639N@72273|Thiotrichales 72273|Thiotrichales S ChaB - - - ko:K06197 - - - - ko00000 - - - ChaB k141_7337_1 1288826.MSNKSG1_15966 2.28e-122 354.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,4651J@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_1815_4 1288826.MSNKSG1_11598 0.0 1809.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,464NI@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0339 Transketolase_N k141_1815_5 1288826.MSNKSG1_11603 0.0 924.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria,46A82@72275|Alteromonadaceae 1236|Gammaproteobacteria E lysine 2,3-aminomutase - - - - - - - - - - - - Fer4_14 k141_1815_6 1288826.MSNKSG1_11608 1.1e-61 196.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3118 Thioredoxin domain-containing protein ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_423_2 580332.Slit_2150 1.45e-93 284.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_7372_1 367336.OM2255_09766 8.6e-111 343.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_11560_1 377629.TERTU_1663 9.88e-107 318.0 COG3455@1|root,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1RPVN@1236|Gammaproteobacteria,2PPFB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Type VI secretion system protein DotU - - - ko:K11892 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DotU k141_15771_1 1177154.Y5S_00370 6.62e-36 125.0 COG1017@1|root,COG1017@2|Bacteria,1QUQ4@1224|Proteobacteria,1SAA1@1236|Gammaproteobacteria,1XQ83@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the globin family - - - - - - - - - - - - Globin k141_15771_2 1298593.TOL_1458 1.59e-49 164.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,1XJT0@135619|Oceanospirillales 135619|Oceanospirillales T response regulator nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg k141_22023_1 1131813.AQVT01000001_gene1333 1.26e-17 81.3 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TRCP@28211|Alphaproteobacteria,1JSJQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_22023_2 1026882.MAMP_01706 6.89e-61 191.0 COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,1S85W@1236|Gammaproteobacteria,461GM@72273|Thiotrichales 72273|Thiotrichales K NikR C terminal nickel binding domain - - - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 k141_12288_1 1407650.BAUB01000003_gene868 7.3e-14 69.7 COG3012@1|root,COG3012@2|Bacteria,1G5EW@1117|Cyanobacteria,1H13U@1129|Synechococcus 1117|Cyanobacteria S SEC-C motif - - - ko:K09858 - - - - ko00000 - - - SEC-C k141_1129_2 1288826.MSNKSG1_15656 5.69e-130 370.0 COG1896@1|root,COG1896@2|Bacteria,1MVGJ@1224|Proteobacteria,1RSED@1236|Gammaproteobacteria,465YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates yfbR GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0010139,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032262,GO:0034641,GO:0034654,GO:0042578,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046078,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0050897,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.89 ko:K08722 ko00240,ko01100,map00240,map01100 - R01569,R01664,R01968,R02088,R02102,R10776 RC00017 ko00000,ko00001,ko01000 - - iB21_1397.B21_02176,iEC55989_1330.EC55989_2535,iECBD_1354.ECBD_1368,iECB_1328.ECB_02216,iECD_1391.ECD_02216,iECH74115_1262.ECH74115_3430,iECIAI1_1343.ECIAI1_2365,iECIAI39_1322.ECIAI39_2438,iECO111_1330.ECO111_3039,iECO26_1355.ECO26_3279,iECSE_1348.ECSE_2548,iECSP_1301.ECSP_3165,iECUMN_1333.ECUMN_2630,iECs_1301.ECs3175,iEcHS_1320.EcHS_A2440,iEcSMS35_1347.EcSMS35_2446,iEcolC_1368.EcolC_1361,iG2583_1286.G2583_2828,iSFV_1184.SFV_2358,iSF_1195.SF2367,iSFxv_1172.SFxv_2612,iS_1188.S2502,iYL1228.KPN_02681,iZ_1308.Z3552 HD_3 k141_1129_3 1288826.MSNKSG1_15661 5.89e-190 528.0 COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,1T1MG@1236|Gammaproteobacteria,46725@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_1129_4 1288826.MSNKSG1_15666 6.17e-242 667.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S96A@1236|Gammaproteobacteria,469V6@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - GGDEF k141_1129_5 1288826.MSNKSG1_15671 3.57e-191 530.0 COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,464JV@72275|Alteromonadaceae 1236|Gammaproteobacteria S glutamine amidotransferase yafJ - - - - - - - - - - - GATase_4 k141_1129_6 1288826.MSNKSG1_15676 2.66e-215 594.0 COG3687@1|root,COG3687@2|Bacteria,1R74T@1224|Proteobacteria,1RZES@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metal-dependent hydrolase - - - ko:K07044 - - - - ko00000 - - - Metal_hydrol k141_1129_7 1288826.MSNKSG1_15681 1.2e-254 700.0 COG2207@1|root,COG2207@2|Bacteria,1NUXY@1224|Proteobacteria,1SNBP@1236|Gammaproteobacteria,46CND@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_13670_1 396588.Tgr7_1499 3.22e-40 156.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF k141_12984_1 1288826.MSNKSG1_07268 7.87e-68 210.0 COG1309@1|root,COG1309@2|Bacteria,1R13H@1224|Proteobacteria,1SD8W@1236|Gammaproteobacteria,4697I@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_12984_2 1288826.MSNKSG1_07273 0.0 1126.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,4652J@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iUTI89_1310.UTI89_C0210 HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_12984_3 1288826.MSNKSG1_07278 3.69e-235 649.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,465JA@72275|Alteromonadaceae 1236|Gammaproteobacteria M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_12984_4 1288826.MSNKSG1_07283 5.64e-110 316.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,46797@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc k141_12984_5 1288826.MSNKSG1_07288 2.13e-183 510.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,464GE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 CTP_transf_3 k141_12984_6 1288826.MSNKSG1_07293 3.22e-39 130.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,4693A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0434 family ycaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09791 - - - - ko00000 - - - Trm112p k141_12984_7 1288826.MSNKSG1_07298 1.08e-244 673.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,466D8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 LpxK k141_12984_8 1288826.MSNKSG1_07303 0.0 1103.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,465QV@72275|Alteromonadaceae 1236|Gammaproteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980 ABC_membrane,ABC_tran k141_12984_9 1288826.MSNKSG1_07308 1.33e-93 273.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,46CRS@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein exbD1 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_12984_10 1288826.MSNKSG1_07313 1.24e-137 390.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,466BI@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_12984_11 1288826.MSNKSG1_07318 5.57e-264 741.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,464JA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DNA internalization-related competence protein ComEC Rec2 ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_21349_1 335543.Sfum_0582 5.97e-15 72.4 COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,43065@68525|delta/epsilon subdivisions,2WV8S@28221|Deltaproteobacteria 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_21349_2 1278309.KB907100_gene2065 5.37e-120 359.0 COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,1RZ3B@1236|Gammaproteobacteria,1XIZI@135619|Oceanospirillales 135619|Oceanospirillales T COG2202 FOG PAS PAC domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9 k141_17862_2 740709.A10D4_07046 2.41e-33 124.0 COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,2QGWC@267893|Idiomarinaceae 1236|Gammaproteobacteria L Alkylated DNA repair protein alkB - - - - - - - - - - - 2OG-FeII_Oxy_2 k141_17115_1 1121448.DGI_0576 2.67e-32 133.0 COG0643@1|root,COG0834@1|root,COG0643@2|Bacteria,COG0834@2|Bacteria,1N315@1224|Proteobacteria,43AUU@68525|delta/epsilon subdivisions,2X68Y@28221|Deltaproteobacteria,2MACZ@213115|Desulfovibrionales 28221|Deltaproteobacteria ENT Bacterial periplasmic substrate-binding proteins - - - - - - - - - - - - HATPase_c,SBP_bac_3 k141_1816_1 314278.NB231_15398 1.9e-45 162.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_12289_1 551275.KB899546_gene2463 1.1e-10 56.2 2EG09@1|root,339SB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_8143_1 1278309.KB907101_gene799 2.31e-157 444.0 COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1XIKR@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_8143_2 1278309.KB907101_gene800 2.91e-258 711.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,1XHUN@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_22025_1 1134474.O59_003786 9.52e-50 174.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1FGMP@10|Cellvibrio 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_19281_1 396588.Tgr7_0573 3.34e-172 491.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1WX3F@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase M20A family. ArgE subfamily - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_11562_1 1500306.JQLA01000013_gene5867 0.000339 42.4 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria,4B9N6@82115|Rhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_7389_2 395493.BegalDRAFT_2912 6.24e-167 480.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,45ZZ3@72273|Thiotrichales 72273|Thiotrichales E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_7389_3 1232683.ADIMK_0332 1.01e-75 242.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,467U6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the Nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_16424_1 1485545.JQLW01000005_gene1063 9.19e-43 152.0 COG2227@1|root,COG2227@2|Bacteria,1QY24@1224|Proteobacteria 1224|Proteobacteria H Pfam Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_10162_1 1232683.ADIMK_3934 3.02e-27 106.0 COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,1RMJ5@1236|Gammaproteobacteria,464B4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_9428_1 713586.KB900536_gene1527 7.03e-30 117.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amino Acid - - - - - - - - - - - - AA_permease_2 k141_9428_2 207954.MED92_00325 1.92e-54 207.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_21368_1 511062.GU3_07405 6.19e-68 213.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1Y4CH@135624|Aeromonadales 135624|Aeromonadales P Binding-protein-dependent transport system inner membrane component - - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_5311_1 1115512.EH105704_04_01490 1.2e-29 120.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,3XQ9C@561|Escherichia 1236|Gammaproteobacteria T CHASE4 domain gmr_2 - - - - - - - - - - - CHASE4,EAL,GGDEF,HAMP,PAS,PAS_4,sCache_3_2 k141_5311_2 545264.KB898744_gene1920 3.75e-29 108.0 COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria 1224|Proteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_8 k141_5311_3 1255043.TVNIR_2245 6.03e-58 186.0 COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,1S6PD@1236|Gammaproteobacteria 1236|Gammaproteobacteria H PFAM Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,TehB k141_1826_1 1535422.ND16A_0732 1.24e-42 150.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 k141_1826_2 1121091.AUMP01000002_gene2140 6.25e-45 162.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl k141_14322_1 1122180.Lokhon_01167 3.37e-10 60.5 COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2P8P1@245186|Loktanella 28211|Alphaproteobacteria C COG2124 Cytochrome P450 pksS - 1.14.14.1 ko:K00493 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko01000 - - - p450 k141_14322_2 398580.Dshi_1160 1.75e-44 152.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM MazG family protein mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG k141_15794_1 1366046.HIMB11_02313 0.000242 49.3 COG3904@1|root,COG3904@2|Bacteria,1NHQR@1224|Proteobacteria,2UJBR@28211|Alphaproteobacteria 28211|Alphaproteobacteria T sh3 domain protein - - - - - - - - - - - - SH3_3 k141_17127_1 1286106.MPL1_12828 1.11e-23 94.7 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning XCC1889 - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_17127_2 765914.ThisiDRAFT_0138 2.46e-38 141.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT CheW domain protein VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_17127_3 1121878.AUGL01000022_gene3648 7.53e-66 205.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis signal transduction protein cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_17127_4 207954.MED92_16855 9.49e-13 68.2 2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1XKJY@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2802) - - - - - - - - - - - - DUF2802 k141_17127_5 1444306.JFZC01000089_gene1423 1.1e-14 70.9 COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,4HPCF@91061|Bacilli,26P2R@186821|Sporolactobacillaceae 91061|Bacilli S FlhB HrpN YscU SpaS Family ylqH - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 k141_1145_1 697281.Mahau_1501 4.56e-18 86.3 COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales 186801|Clostridia T PFAM sigma-54 factor interaction domain-containing protein - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_1145_2 2340.JV46_08400 1.8e-101 318.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,1J5AV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor oprC - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_12310_1 1552758.NC00_02105 4.38e-07 59.7 COG1729@1|root,COG1729@2|Bacteria,1QU1J@1224|Proteobacteria,1T1M5@1236|Gammaproteobacteria,1X64F@135614|Xanthomonadales 135614|Xanthomonadales S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - - k141_12310_2 670487.Ocepr_0269 2.26e-19 94.7 COG0705@1|root,COG0705@2|Bacteria,1WIDY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid k141_9429_1 1458357.BG58_22605 2.99e-19 84.3 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria,1K734@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - DUF1269 k141_4635_1 1026882.MAMP_01203 6.35e-36 129.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,460T0@72273|Thiotrichales 72273|Thiotrichales H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_13687_1 1380380.JIAX01000013_gene3023 5.13e-142 416.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2TQR4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family betS - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_1146_1 1278309.KB907111_gene3363 8.54e-42 156.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XH4C@135619|Oceanospirillales 135619|Oceanospirillales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_17128_1 270374.MELB17_16378 1.75e-06 50.4 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_2497_1 1288826.MSNKSG1_05928 0.0 1377.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,4662I@72275|Alteromonadaceae 1236|Gammaproteobacteria G Protein of unknown function (DUF3417) - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_2497_2 1288826.MSNKSG1_05923 0.0 912.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,46681@72275|Alteromonadaceae 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_2497_3 1288826.MSNKSG1_05918 1.47e-116 335.0 COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria,1SDGE@1236|Gammaproteobacteria,469A8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_2497_4 1288826.MSNKSG1_05913 4.94e-126 359.0 COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,467N3@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria acpH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576 3.1.4.14 ko:K08682 ko00770,map00770 - R01623 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426 ACP_PD k141_2497_5 1288826.MSNKSG1_05908 7.81e-132 375.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SARP@1236|Gammaproteobacteria,46CT7@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_2497_6 1288826.MSNKSG1_05903 3.05e-259 709.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,465KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1064 Zn-dependent alcohol dehydrogenases yahK GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_2497_7 1288826.MSNKSG1_05898 5.08e-15 73.6 COG0369@1|root,COG3182@1|root,COG0369@2|Bacteria,COG3182@2|Bacteria,1MWYV@1224|Proteobacteria,1RY05@1236|Gammaproteobacteria,465H6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Flavodoxin cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,FAD_binding_6,Flavodoxin_1,NAD_binding_1,PepSY_TM k141_19297_1 588596.U9TBC5 9.6e-39 145.0 COG0494@1|root,2QT89@2759|Eukaryota,38BE4@33154|Opisthokonta,3NYM0@4751|Fungi 4751|Fungi L Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 k141_12311_1 765914.ThisiDRAFT_1039 2.52e-65 219.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_5977_1 1288826.MSNKSG1_04756 4.92e-09 56.2 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_5977_2 1288826.MSNKSG1_04746 2.95e-69 209.0 COG0526@1|root,COG0526@2|Bacteria,1MZ6D@1224|Proteobacteria,1SDKQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Thioredoxin - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_16426_1 998674.ATTE01000001_gene2628 1.79e-20 88.6 COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,1T4CA@1236|Gammaproteobacteria,463WF@72273|Thiotrichales 72273|Thiotrichales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_22085_1 400668.Mmwyl1_1829 4.02e-114 337.0 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,1RNA4@1236|Gammaproteobacteria,1XIR5@135619|Oceanospirillales 135619|Oceanospirillales C oxidoreductase FAD NAD(P)-binding - - - ko:K03863 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001 - - - Fer2,NAD_binding_1 k141_22085_2 744980.TRICHSKD4_0438 1.5e-134 393.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TRHD@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_12383_2 1121447.JONL01000005_gene1543 1.9e-18 92.8 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2WKXW@28221|Deltaproteobacteria,2M8SB@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD k141_4706_1 717772.THIAE_08045 1.67e-26 117.0 COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 7TMR-DISMED2,7TMR-DISM_7TM,CBS,GAF_2,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,Response_reg k141_4706_2 172088.AUGA01000005_gene7688 2.29e-09 60.1 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria,3K6AV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 k141_5391_1 580332.Slit_2221 6.77e-97 291.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales 28216|Betaproteobacteria S PFAM ATPase associated with various cellular activities AAA_3 moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_1221_2 1041147.AUFB01000003_gene3581 1.48e-06 51.6 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,4BA1A@82115|Rhizobiaceae 28211|Alphaproteobacteria GM Polysaccharide biosynthesis protein lpsB2 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - ko:K13013 - - - - ko00000,ko01005 - - - CoA_binding_3,Polysacc_synt_2 k141_3939_1 929703.KE386491_gene2555 6.93e-29 114.0 COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_9471_1 225937.HP15_3027 1.11e-37 134.0 COG4665@1|root,COG4665@2|Bacteria,1RE14@1224|Proteobacteria,1S582@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - - - - - - - - - - DctQ k141_9471_2 1408164.MOLA814_01248 5.4e-187 528.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria 1224|Proteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP,TAT_signal k141_13072_1 1278309.KB907100_gene2331 0.0 1335.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHMP@135619|Oceanospirillales 135619|Oceanospirillales T Chemotaxis protein histidine kinase and related - - - - - - - - - - - - CheW,HATPase_c,Hpt,Response_reg k141_13072_3 1278309.KB907100_gene2333 1.85e-41 145.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RV93@1236|Gammaproteobacteria,1XR2Y@135619|Oceanospirillales 135619|Oceanospirillales C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_10966_1 765911.Thivi_2122 1.73e-192 544.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales 135613|Chromatiales EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_10966_2 519989.ECTPHS_08246 4.36e-119 352.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1WWFA@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydratase - - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_17950_1 1255043.TVNIR_3050 3.43e-57 184.0 COG1416@1|root,COG1416@2|Bacteria,1RHW0@1224|Proteobacteria 1224|Proteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_21431_1 1408445.JHXP01000001_gene1549 2.29e-15 80.9 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1JE1A@118969|Legionellales 118969|Legionellales M Barrel-sandwich domain of CusB or HlyD membrane-fusion cusB_2 - - - - - - - - - - - CusF_Ec,HlyD_D23 k141_8796_1 1049564.TevJSym_an00780 3.12e-113 342.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1J4QJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_8796_2 697282.Mettu_1212 1.88e-113 328.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XDJM@135618|Methylococcales 135618|Methylococcales C Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_8796_3 765911.Thivi_1869 3.48e-93 284.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_19339_1 1123401.JHYQ01000025_gene3302 3.27e-53 173.0 COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,1S5W6@1236|Gammaproteobacteria,461FH@72273|Thiotrichales 72273|Thiotrichales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_8812_2 1163617.SCD_n00700 5.48e-171 489.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,2VI8G@28216|Betaproteobacteria 28216|Betaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD2 - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_2574_1 205918.Psyr_0671 8.11e-65 207.0 COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,1Z77W@136849|Pseudomonas syringae group 1236|Gammaproteobacteria P Belongs to the binding-protein-dependent transport system permease family IV02_22045 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_2574_2 1122201.AUAZ01000002_gene1066 5.18e-189 533.0 COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,4654P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Branched-chain amino acid transport system / permease component IV02_22040 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_2574_3 1232683.ADIMK_3963 5.91e-272 756.0 COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,46D9T@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_2574_4 1232683.ADIMK_3973 4.6e-96 286.0 COG1309@1|root,COG1309@2|Bacteria,1ND64@1224|Proteobacteria,1RS7A@1236|Gammaproteobacteria,46CWX@72275|Alteromonadaceae 1236|Gammaproteobacteria K YcdC-like protein, C-terminal region - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_3,TetR_N k141_2574_5 1278309.KB907106_gene1344 2.42e-192 537.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1S1MF@1236|Gammaproteobacteria,1XJ0P@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k141_2574_6 1504672.669786460 6.83e-41 139.0 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,4AFZP@80864|Comamonadaceae 28216|Betaproteobacteria S Invasion gene expression up-regulator, SirB sirB - - - - - - - - - - - SirB k141_2574_7 1121374.KB891591_gene3461 1.23e-54 181.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_3956_1 1449351.RISW2_03825 9.79e-20 85.1 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,4KP04@93682|Roseivivax 28211|Alphaproteobacteria S COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins - - - - - - - - - - - - DUF2312 k141_3956_2 1337093.MBE-LCI_3272 4.99e-29 116.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,2P83C@245186|Loktanella 28211|Alphaproteobacteria U Binding-protein-dependent transport system inner membrane component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_15867_1 1278309.KB907106_gene1232 1.87e-38 139.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria,1XIIE@135619|Oceanospirillales 135619|Oceanospirillales P amino acid ABC transporter aapQ - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_15867_2 1278309.KB907106_gene1231 1.23e-231 639.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria,1XI5T@135619|Oceanospirillales 135619|Oceanospirillales ET Amino acid ABC transporter substrate-binding protein aapJ - - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 k141_10989_1 1288826.MSNKSG1_06643 4.67e-105 328.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AM7@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT - - ko:K03556 - - - - ko00000,ko03000 - - - GerE,TPR_19,TPR_4,TPR_8 k141_19359_1 998088.B565_3660 7.27e-15 76.6 COG4968@1|root,COG4968@2|Bacteria,1R4X4@1224|Proteobacteria,1T22U@1236|Gammaproteobacteria,1Y5K3@135624|Aeromonadales 135624|Aeromonadales NU Prokaryotic N-terminal methylation motif - - - ko:K10925 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_8227_1 572480.Arnit_2000 3.24e-08 53.1 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,42X0E@68525|delta/epsilon subdivisions 1224|Proteobacteria S PFAM Transglycosylase-associated protein MA20_01300 - - - - - - - - - - - Transgly_assoc k141_8227_2 396588.Tgr7_3291 4.51e-90 275.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1WXIY@135613|Chromatiales 135613|Chromatiales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_530_1 1283300.ATXB01000001_gene1997 2.77e-29 119.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XFCC@135618|Methylococcales 135618|Methylococcales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_10255_2 314345.SPV1_04098 3.84e-18 80.5 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria 1224|Proteobacteria P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_12407_1 1122599.AUGR01000009_gene2426 2.42e-278 813.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_6710_1 228410.NE0380 8.01e-73 233.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2VH8K@28216|Betaproteobacteria,372JR@32003|Nitrosomonadales 28216|Betaproteobacteria E L-serine dehydratase single chain form sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_3322_1 1089439.KB902250_gene642 2.55e-36 132.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,4611B@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system - - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_3322_2 1123355.JHYO01000001_gene3345 2.46e-14 74.3 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,36YVR@31993|Methylocystaceae 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_16525_1 765698.Mesci_6349 6.33e-67 211.0 COG0457@1|root,COG0457@2|Bacteria,1QWT6@1224|Proteobacteria,2TXSR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_9490_1 1163408.UU9_01584 5.21e-31 114.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1X636@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0307 family - - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_9490_2 95619.PM1_0225485 2.43e-27 102.0 COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF1653 k141_13778_1 76114.ebA3745 2.18e-91 282.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2VH4U@28216|Betaproteobacteria,2KX7R@206389|Rhodocyclales 206389|Rhodocyclales E Lysine 2,3-aminomutase - - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - - k141_13778_2 1121935.AQXX01000144_gene4525 5.69e-61 208.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XHTD@135619|Oceanospirillales 135619|Oceanospirillales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_6046_2 1415779.JOMH01000001_gene2554 4.36e-62 191.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X6V9@135614|Xanthomonadales 135614|Xanthomonadales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions VM57_07835 - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4 k141_6046_3 580327.Tthe_1368 9.56e-11 64.3 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,42FAG@68295|Thermoanaerobacterales 186801|Clostridia L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_531_1 639282.DEFDS_1249 3.03e-14 77.4 COG3267@1|root,COG3267@2|Bacteria,2GFHJ@200930|Deferribacteres 200930|Deferribacteres U AAA domain - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,SH3_3 k141_17978_2 1122149.BACN01000026_gene1562 1.09e-25 102.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,3F6HQ@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 k141_17978_3 876044.IMCC3088_1090 5.36e-11 66.2 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1J6CX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10 k141_15868_1 1049564.TevJSym_cl00010 2.27e-115 347.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1J5GM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1,Thioredoxin_4 k141_1242_1 32049.SYNPCC7002_A2590 4.48e-99 308.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,1H06P@1129|Synechococcus 1117|Cyanobacteria IQ Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II,adh_short,adh_short_C2 k141_1242_2 349521.HCH_05069 1.17e-35 126.0 2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19360_1 203122.Sde_3528 1.18e-42 148.0 COG0625@1|root,COG0625@2|Bacteria,1RAIN@1224|Proteobacteria,1S3Q5@1236|Gammaproteobacteria,46CPJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the GST superfamily - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 k141_11658_1 1346330.M472_11680 1.22e-05 56.6 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG3292@2|Bacteria,4P0IA@976|Bacteroidetes,1J0R8@117747|Sphingobacteriia 976|Bacteroidetes T helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y k141_13779_2 880071.Fleli_1473 1.07e-63 207.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia 976|Bacteroidetes E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_10991_2 713586.KB900536_gene1772 6.48e-17 75.5 COG4568@1|root,COG4568@2|Bacteria 2|Bacteria K rho-dependent transcription termination rof GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K19000 - - - - ko00000,ko03021 - - - ROF k141_10991_3 1122194.AUHU01000011_gene1685 1.86e-14 67.4 2EGSV@1|root,33AIZ@2|Bacteria,1QAWM@1224|Proteobacteria,1T6BX@1236|Gammaproteobacteria,4690W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG k141_532_1 367336.OM2255_13479 1.73e-98 299.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG1760 L-serine deaminase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_18615_1 1123255.JHYS01000009_gene2309 1.44e-131 405.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,4ABM3@80864|Comamonadaceae 28216|Betaproteobacteria F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_15869_1 1237149.C900_04761 4.62e-101 317.0 COG0366@1|root,COG4677@1|root,COG0366@2|Bacteria,COG4677@2|Bacteria,4NHFH@976|Bacteroidetes,47KN5@768503|Cytophagia 976|Bacteroidetes G Alpha amylase, catalytic domain amyS - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1939 k141_6047_1 977880.RALTA_A0305 1.9e-26 106.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VSMR@28216|Betaproteobacteria,1K0MQ@119060|Burkholderiaceae 28216|Betaproteobacteria T response regulator nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg k141_6047_2 1038858.AXBA01000027_gene1375 6.97e-34 120.0 COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2U5M6@28211|Alphaproteobacteria,3EZPA@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Belongs to the globin family MA20_17055 - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - Globin k141_5415_1 1288826.MSNKSG1_05496 1.62e-193 546.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464D8@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_5415_2 1288826.MSNKSG1_05501 5.76e-268 736.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,465B4@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein F gspF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_16526_1 1122599.AUGR01000021_gene3243 1.47e-50 181.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHFD@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_16526_2 396588.Tgr7_2993 3.97e-19 79.7 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Cytochrome oxidase maturation protein ccoS - - - - - - - - - - - FixS k141_8230_1 1249627.D779_1889 2.7e-96 291.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1WX71@135613|Chromatiales 135613|Chromatiales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_11659_1 1410618.JNKI01000004_gene2187 6.74e-25 106.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4H2A6@909932|Negativicutes 909932|Negativicutes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_1913_1 1206777.B195_00645 4.5e-12 65.5 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1Z5J3@136849|Pseudomonas syringae group 1236|Gammaproteobacteria O Magnesium chelatase, subunit ChlI C-terminal comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_1913_2 157783.LK03_06785 2.32e-08 53.9 COG2960@1|root,COG2960@2|Bacteria,1NH9X@1224|Proteobacteria,1SGZ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09806 - - - - ko00000 - - - BMFP k141_1913_3 1121878.AUGL01000007_gene1277 2.55e-34 129.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM conserved - - - - - - - - - - - - Gcw_chp k141_1913_4 1129794.C427_5045 3.09e-48 164.0 2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria,46A4G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_1913_6 2340.JV46_23120 3e-58 192.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J4I3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_9491_1 1288826.MSNKSG1_16871 2.44e-73 224.0 COG1346@1|root,COG1346@2|Bacteria,1R80J@1224|Proteobacteria,1S039@1236|Gammaproteobacteria,46DFX@72275|Alteromonadaceae 1236|Gammaproteobacteria M effector of murein hydrolase - - - - - - - - - - - - LrgB k141_9491_2 1288826.MSNKSG1_16866 1.11e-71 216.0 COG1380@1|root,COG1380@2|Bacteria,1NNNZ@1224|Proteobacteria,1SGEU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Murein hydrolase transporter LrgA - - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA k141_9491_3 1288826.MSNKSG1_16861 3.49e-77 232.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,466WM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaeQ - - - - - - - - - - - YaeQ k141_3323_1 1278309.KB907100_gene2164 1.86e-274 766.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1XIN2@135619|Oceanospirillales 135619|Oceanospirillales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_2219_2 472759.Nhal_2885 1.36e-16 73.2 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins natSF - 2.3.1.102,2.3.1.128 ko:K03789,ko:K03790,ko:K03896 ko00310,ko01120,map00310,map01120 - R03168 RC00004,RC00865 ko00000,ko00001,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_3 k141_2219_3 717231.Flexsi_1409 4.32e-81 248.0 COG1011@1|root,COG1011@2|Bacteria 2|Bacteria S phosphatase activity hadL - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_2219_6 391587.KAOT1_10871 1.68e-96 285.0 COG0860@1|root,COG0860@2|Bacteria,4NR00@976|Bacteroidetes,1I4WN@117743|Flavobacteriia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k141_21109_1 761193.Runsl_0693 1.34e-56 195.0 COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,47MU1@768503|Cytophagia 976|Bacteroidetes T L,D-transpeptidase catalytic domain - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_1522_1 1163617.SCD_n02931 3.87e-60 197.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k141_1522_2 1163617.SCD_n02930 5.5e-109 323.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria 28216|Betaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k141_104_1 754476.Q7A_20 4.94e-24 96.3 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,460ZE@72273|Thiotrichales 72273|Thiotrichales S FxsA cytoplasmic membrane protein - - - ko:K07113 - - - - ko00000 - - - FxsA k141_12001_1 1026882.MAMP_02910 5.98e-13 68.9 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,460FI@72273|Thiotrichales 72273|Thiotrichales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16 k141_12001_3 519989.ECTPHS_08276 2.28e-51 164.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales 135613|Chromatiales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_13395_1 1124780.ANNU01000015_gene2042 2.2e-50 180.0 COG2356@1|root,COG3227@1|root,COG2356@2|Bacteria,COG3227@2|Bacteria,4NEGS@976|Bacteroidetes 976|Bacteroidetes L Nuclease, EndA NucM family - - - - - - - - - - - - Endonuclease_1,LTD,fn3 k141_18260_1 1297569.MESS2_p90048 2.48e-57 193.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,43NVI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family gbsA - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18260_2 1121374.KB891578_gene3278 3.31e-272 752.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_18260_3 1121374.KB891578_gene3277 4.87e-110 326.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1S58F@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG2771 DNA-binding HTH domain-containing proteins - - - - - - - - - - - - GerE k141_8502_2 521719.ATXQ01000001_gene443 1.05e-09 67.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1YDJF@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Tetratricopeptide repeats - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_5743_1 1318628.MARLIPOL_03080 6.6e-105 318.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,46644@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_7108_1 706587.Desti_0914 9.26e-63 214.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria,2MRDM@213462|Syntrophobacterales 28221|Deltaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2,Fer2,Fer2_2 k141_17554_1 1278309.KB907105_gene1458 1.23e-138 421.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales 135619|Oceanospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_16151_1 585423.KR49_00840 7.79e-18 79.0 COG3254@1|root,COG3254@2|Bacteria,1GNNH@1117|Cyanobacteria,1H18D@1129|Synechococcus 1117|Cyanobacteria S rhamnose metabolic process - - - - - - - - - - - - - k141_16151_2 1342299.Z947_1356 7.55e-07 50.4 COG1522@1|root,COG1522@2|Bacteria,1RD38@1224|Proteobacteria,2U64V@28211|Alphaproteobacteria,3ZY3R@60136|Sulfitobacter 28211|Alphaproteobacteria K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_7825_2 1396858.Q666_09830 1.63e-28 105.0 COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,1SEAC@1236|Gammaproteobacteria,46CX7@72275|Alteromonadaceae 1236|Gammaproteobacteria L Helix-turn-helix domain - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_7825_3 1238190.AMQY01000021_gene1539 2.02e-63 202.0 COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales 135619|Oceanospirillales L HTH-like domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_10610_1 95619.PM1_0203705 1.69e-89 276.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria 1236|Gammaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_843_1 1380367.JIBC01000005_gene3005 2.57e-17 80.5 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3ZVID@60136|Sulfitobacter 28211|Alphaproteobacteria C Aldehyde dehydrogenase family aldA - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_843_2 1144672.F966_01200 1.03e-09 60.5 COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,1S158@1236|Gammaproteobacteria,3NKEH@468|Moraxellaceae 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_11324_1 367336.OM2255_12617 3.3e-98 312.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family soxA - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_20386_1 983545.Glaag_2660 1.65e-45 161.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_20386_2 1278309.KB907100_gene1913 4.82e-44 143.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1XKJQ@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_20386_3 1278309.KB907100_gene1912 3.36e-110 318.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1XJBJ@135619|Oceanospirillales 135619|Oceanospirillales J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_2927_1 1121374.KB891588_gene3289 8.12e-17 84.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_12687_1 990073.ATHU01000001_gene1295 1.54e-13 76.3 COG3203@1|root,COG3203@2|Bacteria,1QZ2J@1224|Proteobacteria,42UFK@68525|delta/epsilon subdivisions,2YQ0J@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M outer membrane porin, OprD family - - - - - - - - - - - - OprD k141_105_1 1234364.AMSF01000013_gene633 1.03e-103 317.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1X5B4@135614|Xanthomonadales 135614|Xanthomonadales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_3632_2 748247.AZKH_3098 1.08e-79 253.0 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales 206389|Rhodocyclales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_1523_1 580332.Slit_1176 3.25e-67 231.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria 28216|Betaproteobacteria S alpha-2-macroglobulin domain protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl k141_15511_1 583355.Caka_1885 4.8e-41 148.0 COG0438@1|root,COG0438@2|Bacteria,46UFK@74201|Verrucomicrobia,3K76E@414999|Opitutae 414999|Opitutae M glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_15511_2 1049564.TevJSym_bi00100 1.72e-188 538.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1J56U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the acetyltransferase family. ArgA subfamily argA GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226 AA_kinase,Acetyltransf_1 k141_15511_3 1382304.JNIL01000001_gene1874 7.13e-91 274.0 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,4HDFS@91061|Bacilli 91061|Bacilli L Site-specific DNA-methyltransferase (Adenine-specific) dpnM - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k141_4324_1 1278309.KB907099_gene3121 3.31e-98 293.0 COG2199@1|root,COG2199@2|Bacteria 2|Bacteria T diguanylate cyclase activity - - - - - - - - - - - - GGDEF,PAS_3 k141_4324_2 1278309.KB907099_gene3120 1.39e-134 390.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XI3K@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_13396_2 247634.GPB2148_2668 1.81e-76 236.0 COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,1J535@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_10611_1 1234364.AMSF01000055_gene1048 1.55e-101 302.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1RZ95@1236|Gammaproteobacteria,1X3T7@135614|Xanthomonadales 135614|Xanthomonadales P transport protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_17555_1 314271.RB2654_07606 3.35e-112 335.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.67 ko:K21802 ko00627,ko01120,map00627,map01120 - R05699 RC00075 ko00000,ko00001,ko01000 - - - Aldedh k141_12002_1 1026882.MAMP_01501 4.57e-31 116.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,460J5@72273|Thiotrichales 72273|Thiotrichales M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_14086_1 29581.BW37_02741 2.49e-11 68.9 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,2VTSF@28216|Betaproteobacteria,474BJ@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_19651_1 95619.PM1_0214310 2.19e-94 294.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1SJRH@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc_2 k141_6397_1 1095769.CAHF01000022_gene432 4.05e-56 208.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_2928_1 1288826.MSNKSG1_01483 1.89e-121 354.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,46759@72275|Alteromonadaceae 1236|Gammaproteobacteria CE COG0473 Isocitrate isopropylmalate dehydrogenase yeaU GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0006082,GO:0006108,GO:0008150,GO:0008152,GO:0009027,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_1288 Iso_dh k141_18261_1 187272.Mlg_2262 2.56e-75 237.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1WVWR@135613|Chromatiales 135613|Chromatiales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_18261_2 1249627.D779_1391 1.73e-18 80.5 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales 135613|Chromatiales O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA k141_12688_1 1123368.AUIS01000032_gene1395 2.46e-38 146.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_106_2 1123368.AUIS01000003_gene1845 5.78e-19 82.8 COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1S6Y0@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,LGT,Redoxin k141_20387_1 754476.Q7A_1163 1.01e-10 63.2 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,4616F@72273|Thiotrichales 72273|Thiotrichales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_20387_2 391615.ABSJ01000017_gene1629 1e-17 82.8 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1J4YQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_9177_1 886379.AEWI01000013_gene2164 1.45e-99 301.0 COG1883@1|root,COG1883@2|Bacteria,4NGCN@976|Bacteroidetes,2FNXC@200643|Bacteroidia,3XIN8@558415|Marinilabiliaceae 976|Bacteroidetes C Na+-transporting oxaloacetate decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta k141_21110_1 1469613.JT55_11610 1.57e-161 458.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3FDJB@34008|Rhodovulum 28211|Alphaproteobacteria E TOBE domain MA20_32190 - 3.6.3.31 ko:K02052,ko:K11072 ko02010,ko02024,map02010,map02024 M00193,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11,3.A.1.11.1 - - ABC_tran,TOBE_2 k141_16871_1 1396141.BATP01000058_gene2059 4.91e-16 80.5 COG4585@1|root,COG4585@2|Bacteria,46TVJ@74201|Verrucomicrobia,2IV6E@203494|Verrucomicrobiae 74201|Verrucomicrobia T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,Response_reg k141_16871_2 587753.EY04_21320 2.08e-63 203.0 COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,1S7UX@1236|Gammaproteobacteria 1236|Gammaproteobacteria K luxR family - - - ko:K14979 ko02020,map02020 M00663 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_16871_3 95619.PM1_0229810 8.99e-45 155.0 COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,1S7UX@1236|Gammaproteobacteria 1236|Gammaproteobacteria K luxR family - - - ko:K14979 ko02020,map02020 M00663 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_5745_1 1380350.JIAP01000011_gene6367 2.06e-28 112.0 COG5430@1|root,COG5430@2|Bacteria,1RM0N@1224|Proteobacteria,2U7IU@28211|Alphaproteobacteria,43IGG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S PFAM Spore coat protein U - - - - - - - - - - - - SCPU k141_14795_1 870187.Thini_1330 7.55e-95 284.0 COG5424@1|root,COG5424@2|Bacteria,1NM66@1224|Proteobacteria,1T5C6@1236|Gammaproteobacteria,463GP@72273|Thiotrichales 72273|Thiotrichales H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_7109_1 1288826.MSNKSG1_08523 1e-105 306.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,466US@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 AIRC k141_7109_2 1288826.MSNKSG1_08518 5.39e-85 259.0 COG4223@1|root,COG4223@2|Bacteria,1NQ3D@1224|Proteobacteria,1T350@1236|Gammaproteobacteria 1236|Gammaproteobacteria DZ transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - - k141_2220_1 91464.S7335_1762 1.06e-16 80.1 COG0477@1|root,COG2814@2|Bacteria,1GCME@1117|Cyanobacteria 1117|Cyanobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_2220_2 396588.Tgr7_1990 9.35e-67 236.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg k141_4325_1 367336.OM2255_06210 1.36e-176 508.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_13397_1 472759.Nhal_3603 6.33e-86 262.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales 135613|Chromatiales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_3633_1 371731.Rsw2DRAFT_2645 2.05e-150 453.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,1FB8V@1060|Rhodobacter 28211|Alphaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_12689_1 1208323.B30_19387 6.46e-13 68.6 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,2TSFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type proline glycine betaine transport systems, periplasmic components - - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_12689_2 744980.TRICHSKD4_3186 1.98e-17 78.2 COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Electron transfer DM13 - - - - - - - - - - - - DM13 k141_15512_1 580332.Slit_2529 1.68e-68 220.0 COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2VHEE@28216|Betaproteobacteria,44WAH@713636|Nitrosomonadales 28216|Betaproteobacteria P PFAM iron permease FTR1 - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_16153_1 713586.KB900536_gene2603 2.78e-109 329.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1WWD2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_7827_1 555088.DealDRAFT_0838 1.96e-49 169.0 COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,42KDU@68298|Syntrophomonadaceae 186801|Clostridia O TIGRFAM hydrogenase expression formation protein HypE hypE - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_7827_2 1321778.HMPREF1982_04094 5.84e-08 54.3 COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia 186801|Clostridia O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_14087_1 1278309.KB907102_gene228 1.37e-141 419.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XHPB@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_5746_1 391613.RTM1035_02940 3.99e-91 278.0 COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,2TRR5@28211|Alphaproteobacteria,46PPS@74030|Roseovarius 28211|Alphaproteobacteria H COG2241 Precorrin-6B methylase 1 cobL - 2.1.1.132 ko:K00595 ko00860,ko01100,map00860,map01100 - R05149 RC00003,RC01279 ko00000,ko00001,ko01000 - - - PCMT,TP_methylase k141_18280_1 338969.Rfer_3395 9.96e-57 202.0 COG0457@1|root,COG2202@1|root,COG5001@1|root,COG0457@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_2949_1 351348.Maqu_0236 3.39e-79 243.0 COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,46ABE@72275|Alteromonadaceae 1236|Gammaproteobacteria L DDE domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k141_8519_1 1122197.ATWI01000011_gene433 5.77e-57 184.0 COG3103@1|root,COG3103@2|Bacteria,1RAGW@1224|Proteobacteria,1S3CH@1236|Gammaproteobacteria,4674C@72275|Alteromonadaceae 1236|Gammaproteobacteria T Bacterial SH3 domain - - - - - - - - - - - - OMP_b-brl,SH3_3 k141_7839_2 90813.JQMT01000001_gene1162 1.6e-100 301.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,460BD@72273|Thiotrichales 72273|Thiotrichales P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_1548_2 2340.JV46_23290 3.31e-71 219.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1J5QA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_1548_3 1123368.AUIS01000001_gene1852 3.81e-71 222.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family csgA - - - - - - - - - - - adh_short k141_17580_1 1469613.JT55_15610 4.26e-70 225.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family aldA - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_4351_2 396588.Tgr7_0544 1.38e-52 171.0 2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10634_1 1123400.KB904756_gene2659 7.05e-46 151.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,460K9@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_10634_3 1134474.O59_003960 1.29e-107 332.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1FI6X@10|Cellvibrio 1236|Gammaproteobacteria C Multicopper oxidase pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_17048_1 4081.Solyc01g007640.2.1 4.35e-220 667.0 2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids 35493|Streptophyta C Plant protein of unknown function (DUF825) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464 - - - - - - - - - - AAA,DUF825 k141_10046_1 1122180.Lokhon_01169 5.14e-29 117.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2P9A4@245186|Loktanella 28211|Alphaproteobacteria T Sigma-54 interaction domain dctD2 - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_12188_1 1120956.JHZK01000014_gene1747 2.74e-73 245.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JN4S@119043|Rhodobiaceae 28211|Alphaproteobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_3807_1 1234364.AMSF01000086_gene2850 2.81e-97 292.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1X3B7@135614|Xanthomonadales 135614|Xanthomonadales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k141_8053_1 195105.CN97_20310 4.85e-110 340.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_21276_1 1384054.N790_11995 1.16e-30 117.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1X3E5@135614|Xanthomonadales 135614|Xanthomonadales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_21276_2 1123401.JHYQ01000028_gene3156 2.18e-13 72.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_10807_1 644801.Psest_0181 2.47e-72 228.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1Z04B@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_2953 GCV_T,GCV_T_C k141_8685_1 1278309.KB907102_gene206 3.8e-61 202.0 COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria,1XJ1Q@135619|Oceanospirillales 135619|Oceanospirillales P Domain present in carbohydrate binding proteins and sugar hydrolses - - - ko:K07218 - - - - ko00000 - - - NosD k141_3146_1 1163617.SCD_n02058 2.02e-16 82.4 COG2199@1|root,COG3159@1|root,COG3159@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WEJC@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - DUF484,GGDEF k141_4533_1 85643.Tmz1t_1822 3.09e-51 167.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2VT25@28216|Betaproteobacteria 28216|Betaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_4533_2 715451.ambt_15510 1.35e-09 60.8 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,466TP@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0739 Membrane proteins related to metalloendopeptidases nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_10047_1 1198232.CYCME_1504 8.46e-35 134.0 COG0784@1|root,COG3852@1|root,COG0784@2|Bacteria,COG3852@2|Bacteria,1NC9X@1224|Proteobacteria,1T242@1236|Gammaproteobacteria 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_12902_2 1122599.AUGR01000009_gene2472 7.26e-131 379.0 COG0697@1|root,COG0697@2|Bacteria,1RDMA@1224|Proteobacteria,1S4HK@1236|Gammaproteobacteria,1XH26@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_12902_3 1232683.ADIMK_0850 1.52e-231 650.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,46681@72275|Alteromonadaceae 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_12902_4 1232683.ADIMK_0849 2.76e-168 491.0 COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,468PS@72275|Alteromonadaceae 1236|Gammaproteobacteria T Domain of unknown function (DUF4118) kdpD - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,GAF_3,HATPase_c,HisKA,KdpD,PAS_7,Usp k141_12902_5 1232683.ADIMK_0848 2.29e-117 341.0 COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria,4678C@72275|Alteromonadaceae 1236|Gammaproteobacteria T Transcriptional regulatory protein, C terminal kdpE - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_10073_1 1232683.ADIMK_4107 2.16e-31 117.0 COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,464Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria L PFAM transposase, IS4 family protein insH6 GO:0000271,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006351,GO:0006355,GO:0006629,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009279,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016051,GO:0016070,GO:0016740,GO:0016757,GO:0016758,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019867,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031975,GO:0032196,GO:0032774,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044424,GO:0044444,GO:0044462,GO:0044464,GO:0045226,GO:0045893,GO:0045935,GO:0046379,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1903509,GO:2000112,GO:2001141 - ko:K07481 - - - - ko00000 - - - DDE_Tnp_1,DUF772 k141_10073_2 686578.AFFX01000001_gene1696 4.16e-75 237.0 COG0583@1|root,COG0583@2|Bacteria,1MXR5@1224|Proteobacteria,1SYUU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_3163_1 373994.Riv7116_2250 1.2e-39 144.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_21968_1 1278309.KB907099_gene2673 1.02e-206 577.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,1XIN0@135619|Oceanospirillales 135619|Oceanospirillales E Sarcosine oxidase, subunit beta - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO k141_21968_2 1278309.KB907099_gene2672 1.96e-182 514.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XH2G@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_17782_1 1515746.HR45_13185 1.26e-93 289.0 28IUP@1|root,2Z8TB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_6570_1 349521.HCH_04836 9.43e-84 259.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1SWUV@1236|Gammaproteobacteria,1XNSP@135619|Oceanospirillales 135619|Oceanospirillales M UDP-N-acetylglucosamine 2-epimerase - - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_6570_2 1069080.KB913028_gene1906 3.55e-35 132.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H4G5@909932|Negativicutes 909932|Negativicutes M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k141_9354_1 1158756.AQXQ01000007_gene339 5.46e-28 117.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales 135613|Chromatiales T PFAM MucB RseB - - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_18441_1 1288826.MSNKSG1_09293 1.69e-123 362.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_18441_2 1288826.MSNKSG1_09288 0.0 1194.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,464TH@72275|Alteromonadaceae 1236|Gammaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_18441_3 1288826.MSNKSG1_09283 8.41e-70 219.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,465RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_16329_2 317025.Tcr_0040 1.41e-70 216.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,460XE@72273|Thiotrichales 72273|Thiotrichales P Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide cynS - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase k141_13572_1 1123400.KB904747_gene622 4.19e-66 218.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - - - - - - - - - - STAS,Sulfate_transp k141_19204_1 143224.JQMD01000002_gene1618 5.33e-69 222.0 COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1I0Q4@117743|Flavobacteriia 976|Bacteroidetes G COG2706 3-carboxymuconate cyclase - - 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase k141_1029_1 1288826.MSNKSG1_06558 5.28e-192 536.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,466N2@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily hcaT - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_350_1 1288826.MSNKSG1_10963 3.35e-48 159.0 COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,1RQ23@1236|Gammaproteobacteria,46590@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitrate reductase, delta subunit narJ GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,ic_1306.c1687 Nitrate_red_del k141_350_2 1288826.MSNKSG1_10958 1.97e-156 439.0 COG2181@1|root,COG2181@2|Bacteria,1MXGZ@1224|Proteobacteria,1RPTD@1236|Gammaproteobacteria,465ID@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitrate reductase, gamma subunit narI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iSF_1195.SF1230,ic_1306.c1897 Nitrate_red_gam k141_350_3 1288826.MSNKSG1_10953 1.23e-185 516.0 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1S2D7@1236|Gammaproteobacteria,465VA@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0760 Parvulin-like peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_5192_1 519989.ECTPHS_07576 1.8e-59 199.0 COG1704@1|root,COG1704@2|Bacteria,1RDUH@1224|Proteobacteria,1S2KR@1236|Gammaproteobacteria,1WY4K@135613|Chromatiales 135613|Chromatiales S E3 Ubiquitin ligase - - - - - - - - - - - - GIDE k141_5192_2 1122599.AUGR01000013_gene746 6.75e-88 263.0 COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,1T06D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_5192_3 1049564.TevJSym_aa00730 1.29e-06 49.3 COG0566@1|root,COG0566@2|Bacteria,1Q9ZC@1224|Proteobacteria,1SWHA@1236|Gammaproteobacteria,1JBBP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J SpoU rRNA Methylase family - - - - - - - - - - - - SpoU_methylase k141_4544_1 1288826.MSNKSG1_02173 0.0 953.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,465RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II acs - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_4544_2 443144.GM21_3642 8.22e-95 290.0 COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria 1224|Proteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23,UT k141_4544_3 1121403.AUCV01000005_gene207 1.29e-127 367.0 COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,42TT9@68525|delta/epsilon subdivisions 1224|Proteobacteria O methyltransferase - - - - - - - - - - - - ICMT,PEMT k141_4544_4 1388763.O165_008295 2.67e-48 184.0 COG2194@1|root,COG2194@2|Bacteria 2|Bacteria T sulfuric ester hydrolase activity - - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1499,DUF1705,Sulfatase k141_8699_1 588596.U9SHL8 4.72e-54 186.0 COG1007@1|root,KOG4668@2759|Eukaryota,38F5W@33154|Opisthokonta,3NZK6@4751|Fungi 4751|Fungi C Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone nad5 - 1.6.5.3 ko:K03883 ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012 M00142 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko03029 3.D.1.6 - - LAGLIDADG_1,NADH5_C,Proton_antipo_M,Proton_antipo_N k141_14258_1 220664.PFL_2164 4.56e-33 124.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1YP2V@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria K LuxR family - - - - - - - - - - - - GerE,Response_reg k141_14258_2 1267580.AF6_1966 8.81e-20 92.8 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,21V88@150247|Anoxybacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,dCache_1 k141_15682_1 1026882.MAMP_02086 4.84e-81 251.0 COG0697@1|root,COG0697@2|Bacteria,1R6CU@1224|Proteobacteria,1SZQJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_12206_1 713586.KB900536_gene547 5.22e-112 328.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1WWUF@135613|Chromatiales 135613|Chromatiales S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin k141_12206_2 1137799.GZ78_01405 8.19e-43 153.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1XHTX@135619|Oceanospirillales 135619|Oceanospirillales M Phospholipase pldA - 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - PLA1 k141_6571_1 1278309.KB907102_gene30 5.77e-90 288.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XI0P@135619|Oceanospirillales 135619|Oceanospirillales D protein involved in exopolysaccharide biosynthesis - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz k141_10076_1 570967.JMLV01000003_gene2363 3.7e-13 68.9 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2TT30@28211|Alphaproteobacteria,2JPVR@204441|Rhodospirillales 204441|Rhodospirillales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_10076_2 1121939.L861_22710 8.52e-40 145.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XI2N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_5923_2 631362.Thi970DRAFT_02257 1.73e-63 203.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales 135613|Chromatiales S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k141_11507_1 1121456.ATVA01000016_gene2040 1.87e-40 154.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales 28221|Deltaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,Response_reg,dCache_2 k141_3164_1 1469613.JT55_09785 3.07e-185 525.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,3FCM3@34008|Rhodovulum 28211|Alphaproteobacteria E Argininosuccinate lyase C-terminal argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_13573_2 795666.MW7_1269 6.12e-76 234.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_17785_1 1122180.Lokhon_00763 2.69e-100 317.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2P8HF@245186|Loktanella 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_14259_1 1408224.SAMCCGM7_c5494 1.76e-22 101.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2TU9Q@28211|Alphaproteobacteria,4BDJD@82115|Rhizobiaceae 28211|Alphaproteobacteria I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_19833_1 452637.Oter_2665 8.83e-41 150.0 COG0415@1|root,COG0415@2|Bacteria,46TVC@74201|Verrucomicrobia,3K926@414999|Opitutae 414999|Opitutae H PFAM DNA photolyase FAD-binding - - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_19833_2 292415.Tbd_1191 4.66e-194 571.0 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KSPT@119069|Hydrogenophilales 119069|Hydrogenophilales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,Response_reg k141_351_1 443152.MDG893_07705 3.29e-40 137.0 2DRYN@1|root,33DQH@2|Bacteria,1NIW2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_351_2 443152.MDG893_07710 4.15e-115 338.0 COG3173@1|root,COG3173@2|Bacteria,1MY0Y@1224|Proteobacteria,1SDMH@1236|Gammaproteobacteria,46B2Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH k141_1031_1 880073.Calab_2906 5.02e-52 184.0 COG1305@1|root,COG1305@2|Bacteria 2|Bacteria E Transglutaminase-like superfamily MA20_22505 - - - - - - - - - - - Transglut_core k141_17786_1 714943.Mucpa_1756 2.23e-59 201.0 COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,1IQAJ@117747|Sphingobacteriia 976|Bacteroidetes G Glycosyl hydrolases family 2, TIM barrel domain - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N k141_12903_1 1288826.MSNKSG1_17046 0.0 1011.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,464GS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_4669 UbiD k141_12903_2 1288826.MSNKSG1_17051 4.24e-131 379.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1RDY0@1224|Proteobacteria,1SYCB@1236|Gammaproteobacteria,46CWP@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases ascD - 1.16.1.3,1.17.1.1,1.5.1.41 ko:K00523,ko:K05368 ko00520,ko00740,ko00860,ko01100,map00520,map00740,map00860,map01100 - R00097,R03391,R03392,R05705 RC00126,RC00220,RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_3165_1 1288826.MSNKSG1_14327 3.38e-143 429.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,465IY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_3822_1 1121396.KB893066_gene1576 3.31e-54 187.0 28HPH@1|root,2Z7XH@2|Bacteria,1Q80I@1224|Proteobacteria,42MX1@68525|delta/epsilon subdivisions,2WKH3@28221|Deltaproteobacteria,2MMPH@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_4546_1 1442599.JAAN01000024_gene1853 9.04e-80 252.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_10077_1 1122137.AQXF01000003_gene2182 1.01e-92 286.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria 2|Bacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_5193_1 395493.BegalDRAFT_1890 5.9e-219 624.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales 72273|Thiotrichales CP Proton-translocating NADH-quinone oxidoreductase, chain L - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_9357_1 713586.KB900536_gene2212 1.17e-37 147.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2QR@135613|Chromatiales 135613|Chromatiales T Histidine Phosphotransfer domain - - 2.7.13.3 ko:K10715 ko02020,ko02024,map02020,map02024 M00517 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,Response_reg k141_14260_2 1123354.AUDR01000016_gene1354 2.52e-05 45.1 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,1KRFR@119069|Hydrogenophilales 119069|Hydrogenophilales J Uncharacterized protein family UPF0004 - - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_8075_1 1121935.AQXX01000124_gene105 3.71e-55 192.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XH2W@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k141_8075_3 1123392.AQWL01000005_gene3024 7.27e-88 275.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2VIBA@28216|Betaproteobacteria 28216|Betaproteobacteria E PFAM glucose-methanol-choline oxidoreductase - - 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 - R01459 RC00146 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k141_6573_1 948106.AWZT01000001_gene4904 5.32e-24 98.6 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VHY2@28216|Betaproteobacteria,1K0GA@119060|Burkholderiaceae 28216|Betaproteobacteria C oxidoreductase FAD NAD(P)-binding domain protein benC - 1.18.1.3 ko:K00529,ko:K05784 ko00071,ko00360,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00071,map00360,map00362,map00364,map00622,map01100,map01120,map01220 M00545,M00551 R02000,R05290,R05291,R05428,R05621,R05622,R05665,R06782,R06783,R08100,R08101,R08108,R08109,R08110 RC00098,RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_6573_2 1245471.PCA10_30910 1.96e-22 94.7 COG1028@1|root,COG1028@2|Bacteria,1MW50@1224|Proteobacteria,1RRIH@1236|Gammaproteobacteria,1YD6Y@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase benD - 1.3.1.25 ko:K05783 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113 RC00271,RC01326,RC01327 br01602,ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k141_15685_1 207954.MED92_17605 4.38e-06 47.8 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XHP7@135619|Oceanospirillales 135619|Oceanospirillales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_15685_2 1051646.VITU9109_06825 4.34e-22 98.6 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XSU6@135623|Vibrionales 135623|Vibrionales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_352_1 1049564.TevJSym_ai00560 1.91e-38 131.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria 1236|Gammaproteobacteria T CBS domain - - - - - - - - - - - - CBS k141_352_2 207954.MED92_02274 1.45e-47 155.0 COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,1XK6I@135619|Oceanospirillales 135619|Oceanospirillales K Nitrogen regulatory protein P-II - - - - - - - - - - - - - k141_20600_1 1288826.MSNKSG1_05461 0.0 1404.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,463XS@72275|Alteromonadaceae 1236|Gammaproteobacteria T GAF domain - - - - - - - - - - - - CZB,EAL,GAF,GAF_2,GGDEF,Hemerythrin,PAS_4,PAS_9,Protoglobin k141_7459_1 765912.Thimo_0822 8.62e-104 320.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_10222_1 857087.Metme_0731 1.6e-10 60.8 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XDTZ@135618|Methylococcales 135618|Methylococcales S modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_10222_2 1323663.AROI01000006_gene2842 1.96e-79 253.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_19957_2 391615.ABSJ01000026_gene120 2.72e-58 206.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1J52P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_21417_1 1288826.MSNKSG1_03141 2.56e-78 241.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,466FV@72275|Alteromonadaceae 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_5376_1 1288826.MSNKSG1_17226 1.08e-223 619.0 COG2207@1|root,COG2207@2|Bacteria,1RH01@1224|Proteobacteria,1S57M@1236|Gammaproteobacteria,46CNC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_17929_1 575586.HMPREF0016_01386 7.37e-09 55.5 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1SNE4@1236|Gammaproteobacteria,3NJV3@468|Moraxellaceae 1236|Gammaproteobacteria K Transcriptional regulatory protein, C terminal - - - ko:K02483,ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_17929_2 697282.Mettu_2361 2.94e-82 271.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1XE6T@135618|Methylococcales 135618|Methylococcales T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_17929_3 95619.PM1_0219330 5.87e-60 211.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase ykoW - - - - - - - - - - - 4HB_MCP_1,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_15845_2 1500893.JQNB01000001_gene508 6.73e-21 93.6 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1X70Z@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4 k141_16483_1 1121271.AUCM01000008_gene3269 1.49e-09 57.4 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k141_22073_1 2340.JV46_08050 1.24e-42 146.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,1S2D9@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator, ArsR family - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese k141_22073_2 395494.Galf_1902 1.59e-18 83.2 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2VP54@28216|Betaproteobacteria 28216|Betaproteobacteria I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase k141_10950_1 1101191.KI912577_gene2842 2.39e-20 97.8 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,1JQVC@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_10950_2 1278309.KB907099_gene2850 6.56e-82 243.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XKEP@135619|Oceanospirillales 135619|Oceanospirillales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_10950_3 1278309.KB907099_gene2849 3.33e-129 370.0 COG0500@1|root,COG2226@2|Bacteria,1MYW1@1224|Proteobacteria,1S707@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_10950_4 1278309.KB907099_gene2848 2.21e-28 103.0 2EG5B@1|root,339X9@2|Bacteria,1NMQV@1224|Proteobacteria,1SIPH@1236|Gammaproteobacteria,1XMTP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10950_5 1278309.KB907099_gene2847 6.95e-216 598.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XI2R@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_10950_6 1278309.KB907099_gene2846 1.4e-181 509.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XH91@135619|Oceanospirillales 135619|Oceanospirillales G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_6004_1 697282.Mettu_1061 3.59e-115 371.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_6688_1 1168067.JAGP01000001_gene544 1.12e-29 116.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,45ZU8@72273|Thiotrichales 72273|Thiotrichales J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_19958_1 1163407.UU7_04682 2.05e-78 244.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1X2XS@135614|Xanthomonadales 135614|Xanthomonadales J Methyltransferase rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_16484_1 1209072.ALBT01000032_gene2045 2.23e-48 175.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1FGIG@10|Cellvibrio 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9 k141_17930_1 522306.CAP2UW1_0922 9.53e-17 80.9 COG5581@1|root,COG5581@2|Bacteria,1RBFR@1224|Proteobacteria,2VQWE@28216|Betaproteobacteria 28216|Betaproteobacteria M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility ycgR - - - - - - - - - - - PilZ,YcgR k141_15086_1 981384.AEYW01000024_gene4015 2.16e-57 190.0 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_1207_1 2340.JV46_17540 2.33e-116 350.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1J70K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Dimerisation domain of Zinc Transporter fieF - - - - - - - - - - - Cation_efflux,ZT_dimer k141_1207_2 1049564.TevJSym_aq00060 3.85e-138 402.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1J4KI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_12364_1 1246995.AFR_37740 2.5e-05 49.3 COG1595@1|root,COG1595@2|Bacteria,2IIKI@201174|Actinobacteria,4DJ40@85008|Micromonosporales 201174|Actinobacteria K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_12364_2 1249627.D779_0089 1.95e-143 426.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales 135613|Chromatiales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_13065_1 568768.CM001975_gene1731 5.82e-23 92.8 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,2JDAU@204037|Dickeya 1236|Gammaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_13065_2 187272.Mlg_0808 1.28e-47 157.0 2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria,1WYGK@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF1841) - - - - - - - - - - - - DUF1841 k141_13065_3 1049564.TevJSym_bw00050 2.1e-45 155.0 COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,1S90I@1236|Gammaproteobacteria,1J6NV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Sigma-70, region 4 sigK - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_13065_4 398527.Bphyt_4573 1.03e-22 100.0 COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2VJ7E@28216|Betaproteobacteria,1K59W@119060|Burkholderiaceae 28216|Betaproteobacteria S Anti-sigma-K factor rskA - - - - - - - - - - - - RskA k141_3302_1 1269813.ATUL01000037_gene1250 7.07e-89 287.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WW6X@135613|Chromatiales 135613|Chromatiales NT Signal transduction histidine kinase - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_5377_1 1042375.AFPL01000041_gene3837 7.45e-118 352.0 COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,1SU06@1236|Gammaproteobacteria,46D8H@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transposase IS66 family - - - - - - - - - - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 k141_11621_1 909613.UO65_2263 5.52e-35 133.0 COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DY9U@85010|Pseudonocardiales 201174|Actinobacteria C aconitate hydratase acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_11621_2 1122212.AULO01000007_gene2314 2.28e-47 162.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1XK8K@135619|Oceanospirillales 135619|Oceanospirillales S High frequency lysogenization protein HflD homolog hflD - - ko:K07153 - - - - ko00000 - - - DUF489 k141_11621_3 1118153.MOY_08738 3.34e-36 134.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XI26@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_14353_2 1278309.KB907106_gene1329 4.7e-68 207.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1XK6F@135619|Oceanospirillales 135619|Oceanospirillales J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_14353_3 1278309.KB907106_gene1328 5.3e-101 295.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1XJA3@135619|Oceanospirillales 135619|Oceanospirillales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_14353_4 1278309.KB907106_gene1327 2.9e-80 239.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1XJMV@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_14353_5 1278309.KB907106_gene1326 1.1e-59 184.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XKDP@135619|Oceanospirillales 135619|Oceanospirillales J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_14353_6 1278309.KB907106_gene1325 5.66e-122 348.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1XHC7@135619|Oceanospirillales 135619|Oceanospirillales J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_14353_7 1278309.KB907106_gene1324 3.23e-63 194.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1XKGV@135619|Oceanospirillales 135619|Oceanospirillales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_14353_9 1278309.KB907106_gene1322 6.14e-53 166.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XKR2@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_14353_10 1278309.KB907106_gene1321 1.48e-31 110.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XM6U@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_14353_11 1278309.KB907106_gene1320 1.35e-86 255.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1XJ5K@135619|Oceanospirillales 135619|Oceanospirillales J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_17186_1 1177181.T9A_01534 1.41e-62 214.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1XJSU@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c k141_17931_1 1116375.VEJY3_16171 1.39e-124 375.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1XV0F@135623|Vibrionales 135623|Vibrionales C COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing torZ - 1.7.2.3 ko:K07811,ko:K07812 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko02000 5.A.3.4 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_10223_1 1318628.MARLIPOL_11851 2.23e-37 126.0 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,1SDJW@1236|Gammaproteobacteria,46BWZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - k141_516_1 1437882.AZRU01000026_gene5948 1.7e-07 53.1 COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,1RS1G@1236|Gammaproteobacteria,1YESM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_516_2 1122201.AUAZ01000015_gene753 3.91e-31 110.0 2E5WI@1|root,330KJ@2|Bacteria,1N6RI@1224|Proteobacteria,1SDNE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nif11 domain - - - - - - - - - - - - Nif11 k141_516_3 1049564.TevJSym_ao00190 7.29e-18 82.4 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1J5RX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074 Metallophos k141_20704_1 1125973.JNLC01000001_gene133 2.4e-21 95.1 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JTUH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain cckA - 2.7.13.3 ko:K13587 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg k141_20704_2 1278309.KB907099_gene2511 2.06e-123 354.0 COG2860@1|root,COG2860@2|Bacteria,1R9H8@1224|Proteobacteria,1S00T@1236|Gammaproteobacteria,1XK63@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - UPF0126 k141_20704_3 1219077.VAZ01S_014_00220 2.27e-152 446.0 COG2199@1|root,COG3706@2|Bacteria,1Q1G1@1224|Proteobacteria,1RYSD@1236|Gammaproteobacteria,1XVS6@135623|Vibrionales 135623|Vibrionales T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_20704_4 1278309.KB907099_gene2512 1.04e-228 639.0 COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,1RP83@1236|Gammaproteobacteria,1XIK7@135619|Oceanospirillales 135619|Oceanospirillales L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C k141_19980_1 644107.SL1157_1734 1.74e-207 585.0 COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria,4NASK@97050|Ruegeria 28211|Alphaproteobacteria S Sugar ABC transporter, ATP-binding protein MA20_34815 - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_7482_1 1123368.AUIS01000007_gene2681 1.51e-181 532.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,2NCDM@225057|Acidithiobacillales 225057|Acidithiobacillales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_7482_2 1280949.HAD_09340 2.18e-10 61.2 COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1MUM1@1224|Proteobacteria,2TUBH@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Iron hydrogenase small subunit - - 1.12.1.2,1.6.5.3 ko:K00336,ko:K18006 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3,SnoaL_4 k141_21442_1 2340.JV46_15210 1.16e-79 256.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225 AMIN,Amidase_3,LysM k141_16518_2 367336.OM2255_06635 2.25e-80 248.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2TR6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, periplasmic component futA1 - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 k141_2566_1 1120998.AUFC01000005_gene691 9.85e-17 81.3 COG1595@1|root,COG1595@2|Bacteria,1VC8N@1239|Firmicutes,24AUU@186801|Clostridia 186801|Clostridia K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_8219_1 1042375.AFPL01000022_gene2684 1.9e-63 204.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,464WJ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_1227_1 1122599.AUGR01000003_gene1989 5.32e-171 491.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RPVB@1236|Gammaproteobacteria,1XHWZ@135619|Oceanospirillales 135619|Oceanospirillales I 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_1227_2 1122599.AUGR01000003_gene1988 1.37e-139 399.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1RPE2@1236|Gammaproteobacteria,1XHX3@135619|Oceanospirillales 135619|Oceanospirillales I enoyl-CoA hydratase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 k141_13764_1 1085623.GNIT_2693 6.86e-28 113.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,464U9@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_19347_1 1288826.MSNKSG1_02604 4.14e-94 286.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,464MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_19347_2 1288826.MSNKSG1_02599 6.16e-212 608.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,465DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_12395_1 215803.DB30_2493 5.3e-06 51.2 COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUG9@29|Myxococcales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - FHA,GAF,GAF_2,Guanylate_cyc k141_12395_2 1121918.ARWE01000001_gene527 3.02e-25 104.0 COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,43SQU@69541|Desulfuromonadales 28221|Deltaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - AsmA k141_7483_1 990285.RGCCGE502_21685 2.2e-96 288.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U221@28211|Alphaproteobacteria,4BAWJ@82115|Rhizobiaceae 28211|Alphaproteobacteria G Branched-chain amino acid transport system / permease component - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 k141_21443_1 1123020.AUIE01000001_gene2328 5.75e-06 48.5 2ARME@1|root,31GY2@2|Bacteria,1QEMH@1224|Proteobacteria,1TBDJ@1236|Gammaproteobacteria,1YH8X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_21443_2 1122164.JHWF01000007_gene1156 1.2e-12 65.9 2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria,1JF01@118969|Legionellales 118969|Legionellales S Domain of unknown function (DUF1840) - - - - - - - - - - - - DUF1840 k141_8220_2 1123360.thalar_02241 1.72e-19 86.7 COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2U49F@28211|Alphaproteobacteria 28211|Alphaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_15106_1 1182590.BN5_02655 1.95e-30 126.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1YI42@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Soluble lytic murein transglycosylase L domain slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_15106_2 344747.PM8797T_12503 9.48e-127 377.0 COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes 203682|Planctomycetes H Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_13765_1 686340.Metal_2699 4.75e-113 342.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XENA@135618|Methylococcales 135618|Methylococcales KLT kinase domain - - - - - - - - - - - - PP2C_2,Pkinase k141_21444_1 443144.GM21_0435 2.61e-62 216.0 COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM conserved repeat domain protein - - - - - - - - - - - - DUF11,SdrD_B k141_12396_1 1049564.TevJSym_ab00910 8.97e-46 164.0 COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1J5FC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S von Willebrand factor type A domain - - - - - - - - - - - - VWA,VWA_3 k141_9479_1 1122194.AUHU01000002_gene2790 1.43e-25 115.0 28M2E@1|root,2ZAGW@2|Bacteria,1R97D@1224|Proteobacteria,1RURR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10974_1 865937.Gilli_3252 3.29e-19 80.1 2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_10974_2 1167006.UWK_00214 4.24e-55 176.0 2DHXS@1|root,32U9Z@2|Bacteria,1N3G8@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_14372_2 1278309.KB907109_gene3310 2.7e-126 361.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,1XKA5@135619|Oceanospirillales 135619|Oceanospirillales S Yip1 domain - - - - - - - - - - - - DUF1282 k141_14372_3 1278309.KB907109_gene3309 6.65e-174 489.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XI1Y@135619|Oceanospirillales 135619|Oceanospirillales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_14372_4 751994.AGIG01000027_gene1399 8.52e-57 192.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1J5KM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_21586_2 523791.Kkor_0352 7.45e-88 265.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1XMSX@135619|Oceanospirillales 135619|Oceanospirillales F COG1428 Deoxynucleoside kinases - - - - - - - - - - - - dNK k141_21586_3 1120963.KB894494_gene3412 4.87e-46 154.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,2Q2NC@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 HPPK k141_6198_1 1198232.CYCME_0263 1.95e-172 492.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,461TD@72273|Thiotrichales 72273|Thiotrichales H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k141_4863_1 545276.KB898726_gene913 3.32e-57 188.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,1S453@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 k141_20817_1 1122599.AUGR01000002_gene3358 1.08e-86 269.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XNV7@135619|Oceanospirillales 135619|Oceanospirillales P Na+/H+ antiporter 1 - - - - - - - - - - - - Na_H_antiport_1 k141_20817_2 1278309.KB907101_gene551 6.81e-105 306.0 COG1280@1|root,COG1280@2|Bacteria,1RASZ@1224|Proteobacteria,1S3FQ@1236|Gammaproteobacteria,1XJ8M@135619|Oceanospirillales 135619|Oceanospirillales E LysE type translocator - - - - - - - - - - - - LysE k141_20817_3 1278309.KB907101_gene550 1.12e-150 429.0 COG2207@1|root,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,1S2Y4@1236|Gammaproteobacteria,1XIPV@135619|Oceanospirillales 135619|Oceanospirillales K AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_18 k141_20817_4 1278309.KB907101_gene549 1.44e-90 268.0 COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,1S6EH@1236|Gammaproteobacteria,1XREI@135619|Oceanospirillales 135619|Oceanospirillales S MOSC domain - - - - - - - - - - - - MOSC k141_20817_5 1278309.KB907101_gene548 6.75e-50 159.0 COG5453@1|root,COG5453@2|Bacteria,1N7WA@1224|Proteobacteria,1SDEZ@1236|Gammaproteobacteria,1XQYJ@135619|Oceanospirillales 135619|Oceanospirillales S activator HlyU - - - - - - - - - - - - HlyU k141_20817_6 1278309.KB907101_gene547 5.94e-77 236.0 2BPVC@1|root,32IP1@2|Bacteria,1RM1M@1224|Proteobacteria,1SF8A@1236|Gammaproteobacteria,1XPGA@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20817_7 1278309.KB907101_gene546 4.58e-72 223.0 2CZND@1|root,32T6R@2|Bacteria,1RKVW@1224|Proteobacteria,1SDSV@1236|Gammaproteobacteria,1XPPV@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_646_1 1337093.MBE-LCI_1012 4.65e-20 87.8 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,2P8B0@245186|Loktanella 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_646_2 1415756.JQMY01000001_gene2805 3.74e-57 192.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2PD4C@252301|Oceanicola 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_14528_2 870187.Thini_3317 7.96e-55 173.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales 72273|Thiotrichales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_16656_1 105559.Nwat_1316 6.81e-22 104.0 COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X1AV@135613|Chromatiales 135613|Chromatiales S Patatin-like phospholipase - - - - - - - - - - - - Patatin k141_18781_1 314285.KT71_10769 1.59e-54 175.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1J4HA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the SUA5 family yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Sua5_yciO_yrdC k141_18781_2 754477.Q7C_2270 3.04e-95 288.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,460K7@72273|Thiotrichales 72273|Thiotrichales S DNA polymerase alpha chain like domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_19470_1 1288826.MSNKSG1_05641 4.59e-83 262.0 COG0515@1|root,COG0515@2|Bacteria,1MWEY@1224|Proteobacteria,1RQHW@1236|Gammaproteobacteria,465AS@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_19470_2 1288826.MSNKSG1_05636 3.02e-137 410.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1SM0Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT helical bimodular (HBM) domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_4864_1 335283.Neut_2185 9.92e-19 85.5 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria 28216|Betaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family czcD1 - - - - - - - - - - - Cation_efflux,ZT_dimer k141_20044_1 323261.Noc_0367 1.18e-35 127.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1WYAH@135613|Chromatiales 135613|Chromatiales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_20044_2 1485544.JQKP01000012_gene2155 4.79e-29 110.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,44VSQ@713636|Nitrosomonadales 28216|Betaproteobacteria K Belongs to the UPF0301 (AlgH) family algH - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_11149_1 1278309.KB907101_gene534 4.7e-200 574.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XHEH@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL - 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_14529_1 1124780.ANNU01000069_gene1097 1.7e-68 224.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_6200_1 519989.ECTPHS_04618 2.9e-38 138.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1WWSE@135613|Chromatiales 135613|Chromatiales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_6200_2 1056820.KB900642_gene414 1.34e-27 111.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,2PMIW@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NT Signal transducing histidine kinase, homodimeric domain cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_17355_1 948106.AWZT01000049_gene509 1.79e-51 164.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae 28216|Betaproteobacteria G peptidyl-prolyl cis-trans isomerase fkpA - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_13938_1 1144672.F966_00272 1.88e-30 118.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,3NKI3@468|Moraxellaceae 1236|Gammaproteobacteria E Belongs to the DegT DnrJ EryC1 family arnB - 2.6.1.104,2.6.1.59 ko:K02805,ko:K18653 - - R10698 RC00006,RC00781 ko00000,ko01000,ko01007 - - - DegT_DnrJ_EryC1 k141_21587_1 292414.TM1040_0321 8.31e-50 163.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2U5T9@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Alkyl hydroperoxide reductase - - - - - - - - - - - - AhpC-TSA k141_21587_2 1469613.JT55_13775 6.02e-45 149.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2U79D@28211|Alphaproteobacteria,3FDAZ@34008|Rhodovulum 28211|Alphaproteobacteria J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_4014_1 1278309.KB907099_gene2961 6.46e-69 214.0 COG1802@1|root,COG1802@2|Bacteria,1MVXM@1224|Proteobacteria,1S0ME@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_4014_2 1278309.KB907099_gene2960 9.45e-314 857.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XI3H@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_4014_3 1278309.KB907099_gene2959 5.95e-175 490.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1XIEB@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_4014_4 1278309.KB907099_gene2957 0.0 905.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHIY@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aldehyde dehydrogenase family - - 1.2.1.39,1.2.1.54,1.2.1.99 ko:K00146,ko:K09472,ko:K12254 ko00330,ko00360,ko00643,ko01100,ko01120,map00330,map00360,map00643,map01100,map01120 M00136 R02536,R02549,R03177,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_4014_5 1278309.KB907099_gene2956 1.23e-72 225.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1S1VT@1236|Gammaproteobacteria,1XREX@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_18782_1 519989.ECTPHS_05345 1.19e-68 217.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales 135613|Chromatiales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_8966_2 1288826.MSNKSG1_17680 2.18e-106 310.0 2E02Y@1|root,32VRV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - SPOR k141_8966_3 1288826.MSNKSG1_17675 2.32e-152 430.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,467TT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_8966_4 1288826.MSNKSG1_17670 1.64e-197 550.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_5557_1 1123236.KB899391_gene3401 4.71e-08 56.2 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,4640C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_5557_2 1123399.AQVE01000018_gene3357 1.77e-24 107.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,45ZQ7@72273|Thiotrichales 72273|Thiotrichales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_3475_1 1278309.KB907107_gene1653 2.96e-176 493.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales 135619|Oceanospirillales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_3475_2 1278309.KB907107_gene1654 2.21e-74 224.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1XKBU@135619|Oceanospirillales 135619|Oceanospirillales P ApaG domain apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_3475_3 1278309.KB907107_gene1655 1.37e-164 464.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XH8Y@135619|Oceanospirillales 135619|Oceanospirillales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_3475_4 1278309.KB907107_gene1656 2.27e-11 59.7 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1XM19@135619|Oceanospirillales 135619|Oceanospirillales P Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide glpE - 2.8.1.1 ko:K02439 ko00920,ko01110,ko01120,map00920,map01110,map01120 - R01931 - ko00000,ko00001,ko01000 - - - Rhodanese k141_14530_1 1278309.KB907103_gene1083 2.28e-68 219.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XHCU@135619|Oceanospirillales 135619|Oceanospirillales V MATE efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_14530_2 1278309.KB907103_gene1084 1.83e-18 83.6 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XI1K@135619|Oceanospirillales 135619|Oceanospirillales I Poly(3-hydroxyalkanoate) synthetase - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N k141_7605_1 1232410.KI421421_gene3529 9.83e-104 340.0 COG2067@1|root,COG2885@1|root,COG2067@2|Bacteria,COG2885@2|Bacteria,1MY5K@1224|Proteobacteria 1224|Proteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - DUF11 k141_7605_2 95619.PM1_0214030 0.00028 43.9 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,1S73A@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Cell wall hydrolase - - - - - - - - - - - - Hydrolase_2 k141_16659_2 688245.CtCNB1_1049 6.57e-08 52.8 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,2VW3E@28216|Betaproteobacteria,4AFQW@80864|Comamonadaceae 28216|Betaproteobacteria NU Type IV minor pilin ComP, DNA uptake sequence receptor pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_21588_1 435908.IDSA_00565 2.31e-17 84.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - - - - - - - - - - GAF,GAF_2,HD,HD_5,Lactamase_B_2 k141_18783_1 228410.NE2123 3.42e-86 269.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2VKQG@28216|Betaproteobacteria,371QI@32003|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the glutamate synthase family glt - - - - - - - - - - - Glu_synthase k141_16020_2 1288826.MSNKSG1_00366 1.84e-129 369.0 COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,1RYPQ@1236|Gammaproteobacteria,469IT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial transferase hexapeptide (six repeats) paaY GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009437,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0044237,GO:0071704,GO:0097164,GO:1901564 - ko:K02617,ko:K08279 - - - - ko00000 - - - Hexapep k141_16020_3 1288826.MSNKSG1_00361 1.4e-185 518.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1RPE2@1236|Gammaproteobacteria,465J5@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase paaG GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1531,iJN746.PP_3283,iYL1228.KPN_01475 ECH_1 k141_16020_4 1288826.MSNKSG1_00356 0.0 946.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RPVB@1236|Gammaproteobacteria,469UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain paaH GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1532,iJN746.PP_3282 3HCDH,3HCDH_N k141_16020_5 1288826.MSNKSG1_00351 8.55e-102 295.0 COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,1S4EZ@1236|Gammaproteobacteria,46B1C@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism paaI GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_1225,iEC55989_1330.EC55989_1532,iECDH10B_1368.ECDH10B_1521,iECDH1ME8569_1439.EcDH1_2249,iECIAI1_1343.ECIAI1_1396,iECO103_1326.ECO103_1533,iECO111_1330.ECO111_1790,iECO26_1355.ECO26_2000,iECSE_1348.ECSE_1481,iEKO11_1354.EKO11_2417,iETEC_1333.ETEC_1471,iEcDH1_1363.EcDH1_2249,iEcE24377_1341.EcE24377A_1581,iEcHS_1320.EcHS_A1483,iEcolC_1368.EcolC_2259,iUMNK88_1353.UMNK88_1803,iY75_1357.Y75_RS07340 4HBT k141_16020_6 1288826.MSNKSG1_00346 1.01e-290 795.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,465T4@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family paaJ GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016740,GO:0016746,GO:0016747,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033554,GO:0033812,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K00632,ko:K02615 ko00071,ko00072,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00360,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095,R09839 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_3476_2 317025.Tcr_0234 1.06e-103 303.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,45ZW8@72273|Thiotrichales 72273|Thiotrichales O Alkyl hydroperoxide reductase - - - - - - - - - - - - AhpC-TSA k141_7606_1 1415754.JQMK01000005_gene1537 3.22e-67 232.0 COG1073@1|root,COG1073@2|Bacteria,1NVTC@1224|Proteobacteria,1RNXQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1073 Hydrolases of the alpha beta superfamily - - - - - - - - - - - - Lipase_bact_N k141_4015_1 156889.Mmc1_2139 6.72e-44 153.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component dctP - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP k141_4015_2 314270.RB2083_2118 2.11e-11 63.5 COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2TU4N@28211|Alphaproteobacteria,3ZHA2@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component dctQ - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ k141_2011_2 1288826.MSNKSG1_15067 8.84e-317 865.0 2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,1SBCM@1236|Gammaproteobacteria,467WI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2868) - - - - - - - - - - - - DUF2868 k141_2011_3 1288826.MSNKSG1_15072 1.75e-78 233.0 2E8EX@1|root,332TA@2|Bacteria,1N97B@1224|Proteobacteria,1SDNS@1236|Gammaproteobacteria,46BXG@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2011_4 1288826.MSNKSG1_15077 0.0 1345.0 2BXCB@1|root,2Z8QU@2|Bacteria,1MZ0I@1224|Proteobacteria,1RRGR@1236|Gammaproteobacteria 1236|Gammaproteobacteria M 3HB-oligomer hydrolase (3HBOH) - - 3.1.1.22 ko:K07518 ko00650,map00650 - R00048 RC00037,RC00094 ko00000,ko00001,ko01000 - - - 3HBOH k141_2011_5 1288826.MSNKSG1_15082 0.0 915.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,469GN@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains - - - ko:K11914 - - - - ko00000,ko02044,ko03000 - - - HTH_8,PAS,PAS_4,Sigma54_activat k141_2011_6 1288826.MSNKSG1_15087 4.81e-252 691.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RRF1@1236|Gammaproteobacteria,46A3T@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_2011_7 1288826.MSNKSG1_15092 2.49e-139 395.0 COG4665@1|root,COG4665@2|Bacteria,1RG47@1224|Proteobacteria,1S3PZ@1236|Gammaproteobacteria,467RR@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_2011_8 1288826.MSNKSG1_15097 3.32e-154 443.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,469I2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_19473_1 1121035.AUCH01000015_gene2492 1.77e-57 199.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVQE@206389|Rhodocyclales 206389|Rhodocyclales T chemotaxis protein - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_2722_2 472759.Nhal_3716 9.1e-225 630.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales 135613|Chromatiales E peptidase M24B, X-Pro dipeptidase aminopeptidase - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_2722_3 314278.NB231_13206 2.11e-52 181.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales 135613|Chromatiales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_7637_1 272123.Anacy_3723 2.82e-39 139.0 COG2267@1|root,COG2267@2|Bacteria,1GQK8@1117|Cyanobacteria,1HTQY@1161|Nostocales 1117|Cyanobacteria I COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_7637_2 1122599.AUGR01000029_gene3021 3.74e-112 339.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1XIIQ@135619|Oceanospirillales 135619|Oceanospirillales T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_17376_1 62928.azo1058 2.04e-35 134.0 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales 206389|Rhodocyclales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_16688_1 1049564.TevJSym_aj00360 1.58e-57 196.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1J4BW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PBP_dimer,Transpeptidase k141_5571_2 1027273.GZ77_12695 1.17e-68 221.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XIGF@135619|Oceanospirillales 135619|Oceanospirillales E glutamate synthase gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 k141_4038_1 1288826.MSNKSG1_00928 3.2e-151 441.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 k141_19479_1 765910.MARPU_11945 1.36e-65 208.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1WWHE@135613|Chromatiales 135613|Chromatiales L hydrolase, TatD family - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_9659_2 1278309.KB907113_gene3326 0.0 2361.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_11767_1 1294273.roselon_02493 2.31e-69 216.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2TUVR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V k141_671_1 570967.JMLV01000018_gene485 1.63e-122 363.0 COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2TRVV@28211|Alphaproteobacteria,2JRW4@204441|Rhodospirillales 204441|Rhodospirillales P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_671_2 1469613.JT55_12000 1.87e-07 51.2 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,3FDJ8@34008|Rhodovulum 28211|Alphaproteobacteria G haloacid dehalogenase-like hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_7638_1 589865.DaAHT2_2257 6.26e-92 286.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales 28221|Deltaproteobacteria NU type II secretion system protein E gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_2743_1 391613.RTM1035_17347 2.03e-104 310.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TQWN@28211|Alphaproteobacteria,46P0A@74030|Roseovarius 28211|Alphaproteobacteria S GTPases (G3E family) cobW - - ko:K02234 - - - - ko00000,ko00001 - - - CobW_C,cobW k141_15220_1 1123393.KB891326_gene8 1.63e-114 338.0 COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2VIY0@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_11948_1 339671.Asuc_0009 1.18e-08 52.8 COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria,1Y97H@135625|Pasteurellales 135625|Pasteurellales S Belongs to the UPF0270 family VY92_03830 - - ko:K09898 - - - - ko00000 - - - UPF0270 k141_11948_2 572477.Alvin_2072 1.25e-07 59.7 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1WWDN@135613|Chromatiales 135613|Chromatiales S PFAM Peptidoglycan-binding lysin domain - - - - - - - - - - - - LysM k141_16818_1 911008.GLAD_02107 6.07e-13 68.9 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_16818_2 1117647.M5M_00555 8.06e-19 89.0 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1J68V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_16818_3 377629.TERTU_4564 3.04e-120 353.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,2PMKP@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H UbiA prenyltransferase family ubiA GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - iZ_1308.Z5639 UbiA k141_16818_4 314287.GB2207_08636 1.49e-40 143.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,1J6IV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_780_1 1216007.AOPM01000053_gene2307 7.71e-25 107.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,2Q1WT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - Peptidase_S9 k141_13353_1 675813.VIB_000252 1.14e-18 88.2 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XSU6@135623|Vibrionales 135623|Vibrionales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_13353_2 626887.J057_12331 7.52e-15 73.9 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,4648A@72275|Alteromonadaceae 1236|Gammaproteobacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_10547_1 472759.Nhal_1702 2.22e-06 47.4 COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,1TKC3@1236|Gammaproteobacteria,1X1RM@135613|Chromatiales 135613|Chromatiales S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT k141_4943_1 1123256.KB907935_gene2471 8e-65 214.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1X4IP@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_8444_1 1249627.D779_4154 9.61e-20 87.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1WWKN@135613|Chromatiales 135613|Chromatiales C C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - k141_8444_3 1415780.JPOG01000001_gene2021 2.15e-32 115.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1X95R@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4212) - - - - - - - - - - - - DUF4212 k141_8444_4 1049564.TevJSym_ar00460 7.44e-53 181.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1J589@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_21052_1 1122137.AQXF01000001_gene3219 2.2e-111 334.0 COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04566 ko00970,map00970 M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1f k141_5695_1 713586.KB900536_gene1289 6.73e-29 122.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C k141_21668_1 715451.ambt_19900 1.14e-128 375.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,46563@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3734,iSBO_1134.SBO_4018 URO-D k141_2164_1 1278309.KB907100_gene2217 4.8e-116 347.0 COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,1RPTW@1236|Gammaproteobacteria,1XH55@135619|Oceanospirillales 135619|Oceanospirillales S FAD-dependent dehydrogenases - - - ko:K07137 - - - - ko00000 - - - - k141_2164_2 1278309.KB907100_gene2212 9.03e-95 292.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XIYC@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_18908_1 252305.OB2597_08744 5.12e-91 280.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2PDJ1@252301|Oceanicola 28211|Alphaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_17484_1 1347342.BN863_870 1.13e-33 124.0 COG0370@1|root,COG0370@2|Bacteria,4P19P@976|Bacteroidetes,1I8DB@117743|Flavobacteriia 976|Bacteroidetes P Ferrous iron transport protein B - - - - - - - - - - - - FeoB_N k141_17484_2 1515615.HQ41_07825 5.94e-19 87.4 COG0370@1|root,COG0370@2|Bacteria,4NGRN@976|Bacteroidetes,2FQQC@200643|Bacteroidia,231FK@171551|Porphyromonadaceae 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_16105_1 1249627.D779_0264 2.22e-129 378.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1WWRP@135613|Chromatiales 135613|Chromatiales C Isocitrate lyase - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_16105_2 572477.Alvin_2014 1.92e-129 392.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1WVZ5@135613|Chromatiales 135613|Chromatiales F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK - 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_16105_3 314292.VAS14_07704 1.88e-61 205.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1XUAW@135623|Vibrionales 135623|Vibrionales F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK - 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK k141_16105_4 1122603.ATVI01000007_gene1619 1.98e-62 206.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1X4BH@135614|Xanthomonadales 135614|Xanthomonadales P chloride channel clcA - - - - - - - - - - - Voltage_CLC k141_781_1 639283.Snov_3842 1.04e-13 71.6 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,3EY49@335928|Xanthobacteraceae 28211|Alphaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_781_2 1121028.ARQE01000003_gene902 5.81e-25 97.8 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,2PK3D@255475|Aurantimonadaceae 28211|Alphaproteobacteria L Uncharacterised protein family UPF0102 MA20_24645 - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_4944_2 1163407.UU7_10705 4.06e-16 80.1 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 k141_6349_1 1163617.SCD_n01209 1.11e-270 767.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.6 ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_11949_1 227377.CBU_0433 4.57e-33 122.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1JE6A@118969|Legionellales 118969|Legionellales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_11949_2 342610.Patl_1493 1.26e-37 129.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems - - - - - - - - - - - - Ion_trans_2 k141_13354_1 1123401.JHYQ01000027_gene3134 2e-103 305.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4608T@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM Serine O-acetyltransferase - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_20330_1 1001585.MDS_3075 3.16e-93 286.0 COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria,1YIGG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF2167) - - - - - - - - - - - - DUF2167 k141_5696_1 551275.KB899546_gene1898 3.27e-12 66.2 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,43W8I@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_75_1 1235457.C404_28300 1.72e-70 229.0 COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,2VNWS@28216|Betaproteobacteria,1K5WZ@119060|Burkholderiaceae 28216|Betaproteobacteria E Creatinase/Prolidase N-terminal domain - - 3.4.11.9,3.4.13.9,3.5.3.3 ko:K01262,ko:K01271,ko:K08688 ko00260,ko00330,ko01100,map00260,map00330,map01100 - R01566 RC00548,RC00549 ko00000,ko00001,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_4961_1 748280.NH8B_1455 9.39e-27 113.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,2KU48@206351|Neisseriales 206351|Neisseriales J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_14053_2 1123392.AQWL01000004_gene2542 1.23e-75 231.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,1KSI4@119069|Hydrogenophilales 119069|Hydrogenophilales J Polypeptide deformylase - - - - - - - - - - - - Pep_deformylase k141_5712_1 1278309.KB907099_gene2826 3.78e-91 266.0 2AIIQ@1|root,3190S@2|Bacteria,1RHWT@1224|Proteobacteria,1S774@1236|Gammaproteobacteria,1XKVK@135619|Oceanospirillales 135619|Oceanospirillales S SMI1-KNR4 cell-wall - - - - - - - - - - - - SUKH_5 k141_5712_2 1278309.KB907099_gene2827 9.7e-26 104.0 COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,1RMHC@1236|Gammaproteobacteria,1XIHV@135619|Oceanospirillales 135619|Oceanospirillales EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_4 k141_4277_1 1116472.MGMO_11c00460 3.36e-46 151.0 COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1XFHS@135618|Methylococcales 135618|Methylococcales C Ferredoxin - - - - - - - - - - - - - k141_4277_2 768671.ThimaDRAFT_4661 4.64e-25 97.4 COG1146@1|root,COG1146@2|Bacteria,1QW5F@1224|Proteobacteria,1T4WS@1236|Gammaproteobacteria,1WYJJ@135613|Chromatiales 135613|Chromatiales C TIGRFAM ferredoxin III - - - - - - - - - - - - Fer4 k141_4277_3 159087.Daro_1509 2.99e-20 82.4 2DQ5Y@1|root,334WI@2|Bacteria,1QWGA@1224|Proteobacteria,2VWW1@28216|Betaproteobacteria,2KXG1@206389|Rhodocyclales 206389|Rhodocyclales S Rop-like - - - - - - - - - - - - Rop-like k141_16118_1 1122599.AUGR01000009_gene2424 9.72e-149 430.0 COG0784@1|root,COG0784@2|Bacteria,1NC9X@1224|Proteobacteria,1SK14@1236|Gammaproteobacteria,1XN6D@135619|Oceanospirillales 135619|Oceanospirillales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_16118_2 1122599.AUGR01000009_gene2423 1.2e-65 224.0 COG2207@1|root,COG3899@1|root,COG2207@2|Bacteria,COG3899@2|Bacteria,1MX23@1224|Proteobacteria,1SYG8@1236|Gammaproteobacteria,1XKV4@135619|Oceanospirillales 135619|Oceanospirillales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_12653_2 351348.Maqu_3550 5.35e-103 303.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,465GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases crp GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,cNMP_binding k141_12653_3 1026882.MAMP_02506 5.75e-61 195.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,46069@72273|Thiotrichales 72273|Thiotrichales E Belongs to the TrpC family trpC - 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PRAI k141_15479_1 1283284.AZUK01000001_gene2306 1.2e-34 119.0 2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,1SCJK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1487_1 998088.B565_3318 1.68e-51 167.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1Y4H6@135624|Aeromonadales 135624|Aeromonadales S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_1487_2 572477.Alvin_1219 4.31e-116 353.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales 135613|Chromatiales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_3599_1 1208323.B30_00220 6.86e-46 154.0 COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,2TRRB@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Precorrin-8X methylmutase cobH - 5.4.99.60,5.4.99.61 ko:K06042 ko00860,ko01100,map00860,map01100 - R05177,R05814 RC01292,RC01980 ko00000,ko00001,ko01000 - - - CbiC k141_20351_1 1278309.KB907104_gene940 2.42e-77 238.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XHZ7@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_8470_1 83219.PM02_15050 6.76e-104 305.0 COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,2U19T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Nitrate reductase, delta subunit narJ - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - - Nitrate_red_del k141_2180_1 314264.ROS217_06429 1.04e-32 130.0 COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,2VD1P@28211|Alphaproteobacteria,46PBI@74030|Roseovarius 28211|Alphaproteobacteria CE leucine binding - - - - - - - - - - - - - k141_11965_1 143224.JQMD01000002_gene2674 1.09e-83 260.0 COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1HX0C@117743|Flavobacteriia 976|Bacteroidetes E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Lyase_1 k141_7792_1 1288298.rosmuc_03143 3.2e-55 184.0 COG0463@1|root,COG0463@2|Bacteria,1R4Y2@1224|Proteobacteria,2U6HZ@28211|Alphaproteobacteria,46PS5@74030|Roseovarius 28211|Alphaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis MA20_42350 - - - - - - - - - - - Glycos_transf_2 k141_6369_1 1121898.Q766_02105 1.91e-123 371.0 COG0277@1|root,COG0277@2|Bacteria,4PCSU@976|Bacteroidetes,1IF9Z@117743|Flavobacteriia,2NYPA@237|Flavobacterium 976|Bacteroidetes C FAD binding domain - - - - - - - - - - - - FAD_binding_4 k141_18230_1 227377.CBU_1148 3.62e-119 379.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1JCJ7@118969|Legionellales 118969|Legionellales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_8471_1 768066.HELO_2215 4.93e-59 196.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1XHYX@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA - 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_7068_1 1288826.MSNKSG1_05898 1.78e-200 573.0 COG0369@1|root,COG3182@1|root,COG0369@2|Bacteria,COG3182@2|Bacteria,1MWYV@1224|Proteobacteria,1RY05@1236|Gammaproteobacteria,465H6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Flavodoxin cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,FAD_binding_6,Flavodoxin_1,NAD_binding_1,PepSY_TM k141_14762_1 545264.KB898747_gene383 7.44e-105 313.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales 135613|Chromatiales S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_14762_2 1123517.JOMR01000001_gene744 1.09e-19 85.9 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales 72273|Thiotrichales HJ Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_12654_1 1318628.MARLIPOL_00130 1.3e-46 160.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,466VG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1512 Beta-propeller domains of methanol dehydrogenase type Z012_08980 - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase k141_76_1 765914.ThisiDRAFT_1454 1.15e-75 238.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_2886_1 768671.ThimaDRAFT_4734 1.23e-75 241.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales 135613|Chromatiales P PFAM Citrate transporter - - - - - - - - - - - - CitMHS k141_18931_1 243233.MCA1234 2.84e-128 377.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XEG7@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_16119_1 1288826.MSNKSG1_08803 1.98e-239 662.0 COG1629@1|root,COG1629@2|Bacteria,1QU6M@1224|Proteobacteria,1T1NT@1236|Gammaproteobacteria,4671Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi k141_9154_1 1278309.KB907099_gene2405 5.55e-47 157.0 COG2186@1|root,COG2186@2|Bacteria,1NXAS@1224|Proteobacteria,1SYY0@1236|Gammaproteobacteria,1XRJC@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_9154_2 1278309.KB907099_gene2404 3.06e-84 254.0 COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1SE1A@1236|Gammaproteobacteria,1XKWE@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09908 - - - - ko00000 - - - DUF1043 k141_9154_3 1278309.KB907099_gene2403 6.26e-151 427.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1XIMF@135619|Oceanospirillales 135619|Oceanospirillales S metal-binding protein - - - - - - - - - - - - NIF3 k141_9154_4 1278309.KB907099_gene2402 9.27e-226 628.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_14054_2 1238450.VIBNISOn1_320012 4.36e-45 159.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XTHH@135623|Vibrionales 135623|Vibrionales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_11298_1 314271.RB2654_03359 2.89e-13 64.3 2EIMJ@1|root,33CCU@2|Bacteria,1NMXZ@1224|Proteobacteria,2U04I@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_11298_2 413404.Rmag_1053 1.38e-48 167.0 COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S pyridine nucleotide-disulphide oxidoreductase sqr - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_15480_1 765914.ThisiDRAFT_2289 4.81e-77 245.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales 135613|Chromatiales HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - ATP-grasp_3,RLAN,RimK k141_15480_2 1026882.MAMP_00249 9.38e-50 174.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,45ZMQ@72273|Thiotrichales 72273|Thiotrichales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_9848_1 713587.THITH_11655 2.73e-74 236.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,1WW06@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_21071_1 1283284.AZUK01000001_gene2308 3.31e-29 105.0 arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,1SHGZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21678_1 345073.VC395_A0162 1.62e-18 92.4 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XVCX@135623|Vibrionales 135623|Vibrionales S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_19,TPR_2,VWA_2 k141_801_1 1278309.KB907100_gene1938 2.68e-200 570.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XH69@135619|Oceanospirillales 135619|Oceanospirillales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_801_2 1278309.KB907100_gene1939 2.21e-94 275.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1XJKE@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_801_3 1278309.KB907100_gene1940 8.6e-69 208.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1XKMS@135619|Oceanospirillales 135619|Oceanospirillales J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_5057_2 1565129.JSFF01000014_gene456 3.45e-33 117.0 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1S9PR@1236|Gammaproteobacteria,2QEPT@267890|Shewanellaceae 1236|Gammaproteobacteria S enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_15570_1 1237149.C900_04189 1.31e-103 322.0 COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,47K30@768503|Cytophagia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_20451_1 713586.KB900536_gene793 1.07e-43 154.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_12074_1 1122201.AUAZ01000014_gene254 3.84e-55 172.0 COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,4687U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - ko:K09700 - - - - ko00000 - - - - k141_12074_2 1121015.N789_12765 2.53e-70 225.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1X591@135614|Xanthomonadales 135614|Xanthomonadales P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1,Thioredoxin_4 k141_21816_2 1279017.AQYJ01000025_gene493 5.14e-93 280.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1RYHH@1236|Gammaproteobacteria,466EQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_21816_3 491952.Mar181_2919 5.68e-72 231.0 COG0583@1|root,COG0583@2|Bacteria,1R7JT@1224|Proteobacteria,1S481@1236|Gammaproteobacteria,1XKV7@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator, LysR - - - - - - - - - - - - HTH_1,LysR_substrate k141_21816_4 550540.Fbal_1752 8.75e-48 166.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_4412_1 95619.PM1_0222730 7.86e-42 150.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Dehydrogenase pedH - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 k141_901_1 1286093.C266_10876 0.0 1098.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria,1K20Q@119060|Burkholderiaceae 28216|Betaproteobacteria E NAD-glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_19065_1 1288826.MSNKSG1_11003 2.72e-87 258.0 COG2846@1|root,COG2846@2|Bacteria 2|Bacteria D Di-iron-containing protein involved in the repair of iron-sulfur clusters ytfE GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564 - ko:K07322 - - - - ko00000 - - iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820 Hemerythrin,ScdA_N k141_19065_2 1288826.MSNKSG1_11008 1.31e-38 129.0 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,469AA@72275|Alteromonadaceae 1236|Gammaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_19065_3 1288826.MSNKSG1_11013 1.05e-75 226.0 COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,1S9PQ@1236|Gammaproteobacteria,468IQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 k141_19065_4 1288826.MSNKSG1_11018 6.56e-221 608.0 COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,4669H@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0826 Collagenase and related proteases yhbV - - - - - - - - - - - Peptidase_U32 k141_19065_5 1288826.MSNKSG1_11038 1.43e-56 184.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,4666C@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0826 Collagenase and related proteases yhbU - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_19715_2 391615.ABSJ01000002_gene489 1.37e-71 219.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1J5R2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_193_1 1278309.KB907099_gene2758 7.5e-103 306.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria,1XJGM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_14157_1 1232683.ADIMK_3131 3.49e-125 364.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RY9X@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PFAM periplasmic binding protein LacI transcriptional regulator - - - ko:K10552 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - Peripla_BP_4 k141_14157_2 1121935.AQXX01000116_gene5187 2.44e-120 355.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XHUE@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10553 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - BPD_transp_2 k141_14874_1 1122134.KB893651_gene1861 3.5e-12 69.3 COG3208@1|root,COG3208@2|Bacteria,1R0QV@1224|Proteobacteria,1T4NZ@1236|Gammaproteobacteria,1XRYX@135619|Oceanospirillales 135619|Oceanospirillales Q Thioesterase involved in non-ribosomal peptide biosynthesis - - - - - - - - - - - - - k141_12782_2 1279009.ADICEAN_03128 9.43e-35 125.0 COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia 976|Bacteroidetes E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_17644_2 1236973.JCM9157_76 1.26e-25 99.4 COG1733@1|root,COG1733@2|Bacteria,1VH3Q@1239|Firmicutes,4HNMI@91061|Bacilli,1ZH91@1386|Bacillus 91061|Bacilli K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_17644_3 377629.TERTU_0145 7.79e-23 102.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RSD8@1236|Gammaproteobacteria,2PQBA@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_4413_2 494416.AYXN01000013_gene134 4.22e-71 220.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,3NK1G@468|Moraxellaceae 1236|Gammaproteobacteria J Forms part of the polypeptide exit tunnel rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_11395_1 983545.Glaag_0688 1.63e-05 46.6 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,464JG@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA helicase recQ1 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind k141_11395_2 1278309.KB907099_gene2997 1.44e-310 848.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XHJF@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family doeD GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045303,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 2.6.1.76 ko:K15785 ko00260,map00260 - R06977 RC00006,RC00062 ko00000,ko00001,ko01000 - - - Aminotran_3 k141_9931_1 713586.KB900536_gene1722 2.7e-86 264.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria 1236|Gammaproteobacteria P 3'(2'),5'-bisphosphate nucleotidase cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313 Inositol_P k141_9931_2 1123392.AQWL01000011_gene2228 6.9e-56 184.0 COG0596@1|root,COG0596@2|Bacteria,1RJQK@1224|Proteobacteria,2W4YC@28216|Betaproteobacteria 28216|Betaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - - k141_9931_3 1168065.DOK_18785 5.79e-35 125.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,1J5ZA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S hydrolase (HAD superfamily) yrfG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_19066_1 248742.XP_005646645.1 9.1e-52 166.0 2BG5J@1|root,2S18N@2759|Eukaryota,37UVZ@33090|Viridiplantae,34P65@3041|Chlorophyta 3041|Chlorophyta - - - - - - - - - - - - - - - k141_12076_1 349124.Hhal_1107 9.18e-45 161.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1X0BN@135613|Chromatiales 135613|Chromatiales G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_12076_2 187272.Mlg_0959 1.59e-10 60.8 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_18338_1 2340.JV46_15060 4.02e-84 258.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1J4Y4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_18338_2 199310.c0204 6.99e-15 76.6 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,3XMCP@561|Escherichia 1236|Gammaproteobacteria J ribosomal protein rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_9231_1 1026882.MAMP_02979 1.44e-14 73.9 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,462KA@72273|Thiotrichales 72273|Thiotrichales S Clan AA aspartic protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_20465_2 545276.KB898732_gene2427 5.17e-58 184.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_20465_3 395961.Cyan7425_2122 2.74e-18 84.7 COG0071@1|root,COG0071@2|Bacteria,1G6EC@1117|Cyanobacteria,3KI1M@43988|Cyanothece 1117|Cyanobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_13462_1 472759.Nhal_1179 4.53e-30 113.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1WXT6@135613|Chromatiales 135613|Chromatiales I PFAM phosphoesterase PA-phosphatase related - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_13462_2 1123393.KB891316_gene1791 6.42e-51 167.0 COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,2WFMV@28216|Betaproteobacteria,1KSR6@119069|Hydrogenophilales 119069|Hydrogenophilales S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_1612_1 998674.ATTE01000001_gene4342 8.71e-109 326.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,45ZV5@72273|Thiotrichales 72273|Thiotrichales S PFAM Phosphotransferase enzyme family - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_7896_1 472759.Nhal_0930 1.62e-67 213.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales 135613|Chromatiales L TIGRFAM Tyrosine recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_7896_2 572477.Alvin_0369 3.21e-64 207.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1WXSE@135613|Chromatiales 135613|Chromatiales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_7896_3 290398.Csal_3035 2.16e-14 74.3 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1XJCT@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin domain-containing protein trx-1 - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_11396_2 1255043.TVNIR_2485 8.56e-60 186.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1WYPR@135613|Chromatiales 135613|Chromatiales K Belongs to the P(II) protein family - - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_19716_1 1049564.TevJSym_aj00290 1.25e-59 198.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1J4RF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_19716_2 1163617.SCD_n02483 6.75e-07 50.8 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria 28216|Betaproteobacteria M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_15576_1 1122201.AUAZ01000005_gene615 4.06e-18 78.2 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,467WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_15576_2 1121479.AUBS01000049_gene737 6.67e-11 60.5 COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2UIEV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT k141_15576_3 1278309.KB907101_gene808 2.09e-109 322.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XH8Q@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_3702_1 379731.PST_0562 4.88e-71 228.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1YZYR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3503,iYL1228.KPN_03625 Fer4_11,Fer4_20,Pyr_redox_2 k141_3702_2 395493.BegalDRAFT_2300 5.79e-314 902.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales 72273|Thiotrichales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_21817_2 1123399.AQVE01000001_gene691 3.98e-113 338.0 COG0842@1|root,COG0842@2|Bacteria,1QTBE@1224|Proteobacteria,1RNG9@1236|Gammaproteobacteria,461U3@72273|Thiotrichales 72273|Thiotrichales V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane k141_7174_1 1288826.MSNKSG1_16081 8.18e-262 719.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,4643C@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_7174_2 1288826.MSNKSG1_16086 0.0 1156.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_7174_3 1288826.MSNKSG1_16091 2.54e-267 731.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily - - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N k141_7174_4 1288826.MSNKSG1_16096 0.0 918.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,465UR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_7174_5 1288826.MSNKSG1_16101 4.01e-122 349.0 COG1309@1|root,COG1309@2|Bacteria,1MZC4@1224|Proteobacteria,1SBVF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - - k141_7174_6 1288826.MSNKSG1_16106 2.61e-184 515.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria,469BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k141_12077_1 1231392.OCGS_2624 3.41e-13 67.8 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria 28211|Alphaproteobacteria E threonine dehydratase tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_12077_2 644076.SCH4B_2914 3.73e-79 247.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,4NBJT@97050|Ruegeria 28211|Alphaproteobacteria E Aminotransferase class-V sgaA - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_14159_2 945713.IALB_2859 1.67e-13 69.7 COG4103@1|root,COG4103@2|Bacteria 2|Bacteria T Tellurite resistance protein TerB - - - - - - - - - - - - TerB k141_6465_1 1301098.PKB_2958 1.92e-21 105.0 COG1361@1|root,COG2202@1|root,COG2931@1|root,COG3210@1|root,COG3898@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2202@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3898@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - 3.4.24.40 ko:K01406,ko:K07004 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - 5_nucleotid_C,DUF4347,HemolysinCabind,Peptidase_M10_C k141_5834_1 1232683.ADIMK_2334 8.05e-269 758.0 COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,1T3G2@1236|Gammaproteobacteria 1236|Gammaproteobacteria H TonB dependent receptor - - - ko:K02014,ko:K16089 - - - - ko00000,ko02000 1.B.14,1.B.14.1,1.B.14.10 - - Plug,TonB_dep_Rec k141_7897_1 595460.RRSWK_01239 9.29e-80 248.0 COG2996@1|root,COG2996@2|Bacteria,2J1Y7@203682|Planctomycetes 203682|Planctomycetes S S1 domain - - - ko:K00243 - - - - ko00000 - - - S1_2 k141_3010_1 1288826.MSNKSG1_07653 3.24e-142 404.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RPS0@1236|Gammaproteobacteria,4665A@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1349 Transcriptional regulators of sugar metabolism glpR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02444 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_3010_2 1288826.MSNKSG1_07658 0.0 990.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,465IW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009331,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0022900,GO:0031224,GO:0031226,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052590,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575,GO:1902494,GO:1990204 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - iSSON_1240.SSON_3663 DAO,DAO_C k141_3010_3 1288826.MSNKSG1_07663 1.78e-151 425.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,4671B@72275|Alteromonadaceae 1236|Gammaproteobacteria L Uracil-DNA glycosylase - - - - - - - - - - - - UDG k141_3010_4 1288826.MSNKSG1_07668 1.05e-165 464.0 COG0778@1|root,COG0778@2|Bacteria,1RBXY@1224|Proteobacteria,1RZZ2@1236|Gammaproteobacteria,46DGW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_3010_5 1288826.MSNKSG1_07673 2.87e-142 406.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iNRG857_1313.NRG857_12000 Glucokinase k141_18339_1 391595.RLO149_c002630 1.5e-190 549.0 COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,2TT7F@28211|Alphaproteobacteria,2P40A@2433|Roseobacter 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component fbpB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_8580_1 857087.Metme_3562 1.92e-64 202.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XDXN@135618|Methylococcales 135618|Methylococcales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg k141_8580_2 1123517.JOMR01000001_gene843 4.62e-09 55.5 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Transglycosylase-associated protein - - - - - - - - - - - - Transgly_assoc k141_8580_3 575589.HMPREF0018_00388 1.43e-05 48.9 2AJVR@1|root,31AIH@2|Bacteria,1QFZZ@1224|Proteobacteria,1TDBM@1236|Gammaproteobacteria,3NQIM@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8580_4 631362.Thi970DRAFT_00969 1.1e-20 82.8 2E4KB@1|root,32ZFA@2|Bacteria,1N6R9@1224|Proteobacteria,1SFP8@1236|Gammaproteobacteria,1WZH8@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8580_5 580332.Slit_1719 6.36e-76 228.0 COG0537@1|root,COG0537@2|Bacteria,1N3EA@1224|Proteobacteria,2VSGA@28216|Betaproteobacteria 28216|Betaproteobacteria FG Histidine triad (Hit) protein - - - - - - - - - - - - HIT k141_13463_1 740709.A10D4_05272 2.33e-26 114.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_7924_2 631362.Thi970DRAFT_00922 6.89e-16 76.6 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1WVUM@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_12097_1 395493.BegalDRAFT_1376 1.2e-105 319.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,460I1@72273|Thiotrichales 72273|Thiotrichales D Part of the ABC transporter FtsEX involved in cellular division - - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_12097_2 1121937.AUHJ01000010_gene1603 6.2e-17 77.8 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,464ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria D ATPase involved in cell division ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_1632_1 498211.CJA_3501 2.01e-45 154.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1FHAZ@10|Cellvibrio 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_7319_1 313603.FB2170_05630 2.7e-45 158.0 COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia,2PG1C@252356|Maribacter 976|Bacteroidetes C ATP synthase A chain atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_7319_2 991.IW20_06855 3.54e-11 58.5 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia,2NXFM@237|Flavobacterium 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_5196_2 1117647.M5M_04265 1.93e-31 121.0 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,1S8XS@1236|Gammaproteobacteria,1J6YY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU carbon utilization mshJ - - ko:K12280 - - - - ko00000,ko02044 - - - PilO,T2SSM k141_3826_1 1229172.JQFA01000002_gene3251 1.35e-07 52.4 COG0527@1|root,COG0527@2|Bacteria,1G095@1117|Cyanobacteria,1H9UH@1150|Oscillatoriales 1117|Cyanobacteria E aspartate kinase, monofunctional class lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iJN678.lysC AA_kinase,ACT,ACT_7 k141_3826_2 1123368.AUIS01000001_gene1860 6.02e-57 197.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,2NCER@225057|Acidithiobacillales 225057|Acidithiobacillales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_2431_2 870187.Thini_3935 1.97e-93 278.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales 72273|Thiotrichales P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_8082_1 935845.JADQ01000025_gene398 1.67e-31 123.0 COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4HE8W@91061|Bacilli,26U7B@186822|Paenibacillaceae 91061|Bacilli L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_8082_2 1388763.O165_021300 3.09e-34 126.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1YVIK@136845|Pseudomonas putida group 1236|Gammaproteobacteria M pfam nlp p60 yafL GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.2.1.14 ko:K01183,ko:K19303 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000,ko01002,ko01011 - GH18 - NLPC_P60 k141_14265_1 930166.CD58_27750 2.78e-31 119.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria 1224|Proteobacteria S Belongs to the UPF0312 family yceI - - - - - - - - - - - YceI k141_14265_2 1232683.ADIMK_0712 6.48e-27 108.0 2AQ39@1|root,31F8I@2|Bacteria,1NK0J@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_19209_1 1123020.AUIE01000027_gene4595 1.99e-24 108.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1YECW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_18448_1 591001.Acfer_1086 3.6e-16 74.3 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,4H5UC@909932|Negativicutes 909932|Negativicutes S VRR_NUC - - - - - - - - - - - - VRR_NUC k141_18448_2 1305735.JAFT01000005_gene3907 2.77e-16 79.7 COG0417@1|root,COG0417@2|Bacteria,1R7PE@1224|Proteobacteria,2TRUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA replication proofreading - - - - - - - - - - - - - k141_17058_1 291112.PAU_01877 2.72e-61 208.0 COG0223@1|root,COG0451@1|root,COG0223@2|Bacteria,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria GJM Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011 ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R02984,R07658,R07660 RC00026,RC00289,RC01575,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 - - iPC815.YPO2420,iSFV_1184.SFV_2325 Epimerase,Formyl_trans_C,Formyl_trans_N k141_4550_1 1168067.JAGP01000001_gene1006 1.76e-128 375.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,46067@72273|Thiotrichales 72273|Thiotrichales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_21293_1 243231.GSU1533 2.69e-24 104.0 COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria,43T50@69541|Desulfuromonadales 28221|Deltaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_21293_2 1278309.KB907100_gene1901 3.03e-83 254.0 COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1XIEJ@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 k141_20605_1 713586.KB900536_gene2882 1.09e-87 267.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1WX6I@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_20605_2 768671.ThimaDRAFT_1999 3.06e-09 56.2 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_19840_1 2340.JV46_23410 3.39e-75 252.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1J8WI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C,Acyltransferase,Aminotran_1_2,NAD_binding_4,PP-binding,Thioesterase k141_8083_1 1049564.TevJSym_ah00930 5.68e-33 123.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1J7ZS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Thiosulfate-oxidizing multienzyme system protein SoxA soxA - 1.8.2.2 ko:K17222,ko:K19713 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 - - - - k141_14266_1 1499684.CCNP01000026_gene3828 8.5e-08 58.2 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,36ESU@31979|Clostridiaceae 186801|Clostridia S Belongs to the UPF0761 family yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_21969_1 1288826.MSNKSG1_10383 1.74e-28 115.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria 1224|Proteobacteria NT Methyl-accepting chemotaxis protein VPA0562 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_21969_2 1288826.MSNKSG1_10388 0.0 1143.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,46464@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k141_21969_3 1288826.MSNKSG1_10393 6.72e-209 578.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_21969_4 1288826.MSNKSG1_10398 9.84e-98 286.0 2C5EJ@1|root,331R8@2|Bacteria,1NDD9@1224|Proteobacteria,1SDIU@1236|Gammaproteobacteria,46BWA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function VcgC/VcgE (DUF2780) PP0330 - - - - - - - - - - - DUF2780 k141_21969_5 1318628.MARLIPOL_03525 3.97e-45 159.0 COG4104@1|root,COG4104@2|Bacteria,1R84C@1224|Proteobacteria,1SZNR@1236|Gammaproteobacteria,46CZD@72275|Alteromonadaceae 1224|Proteobacteria S PAAR motif - - - - - - - - - - - - PAAR_motif k141_21969_7 1288826.MSNKSG1_10428 1.99e-92 271.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,46DJ5@72275|Alteromonadaceae 1236|Gammaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_21969_8 1288826.MSNKSG1_10433 2.27e-122 355.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRKH@1236|Gammaproteobacteria,46CYM@72275|Alteromonadaceae 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GGDEF,HAMP,PAS,PAS_9 k141_1040_1 1278309.KB907099_gene2930 7.46e-58 199.0 COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,1T3FX@1236|Gammaproteobacteria 1236|Gammaproteobacteria C heat shock protein binding - - - - - - - - - - - - Cytochrome_C7 k141_12906_1 1278309.KB907100_gene1971 1.05e-13 68.2 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XR8K@135619|Oceanospirillales 135619|Oceanospirillales KT PFAM response regulator receiver, transcriptional regulator domain-containing protein - - - - - - - - - - - - Response_reg,Trans_reg_C k141_12906_2 1278309.KB907100_gene1970 3.28e-272 751.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1XJSU@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c k141_12906_3 1278309.KB907100_gene1969 3.07e-136 386.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XI3J@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 k141_12906_4 1278309.KB907100_gene1968 2.3e-251 702.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XHE2@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_5198_1 754476.Q7A_1063 6.79e-59 189.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,460ND@72273|Thiotrichales 72273|Thiotrichales O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_19210_1 367336.OM2255_06790 6.16e-105 317.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_15689_2 1278309.KB907110_gene3170 8.07e-178 498.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RY2T@1236|Gammaproteobacteria,1XIHB@135619|Oceanospirillales 135619|Oceanospirillales I Dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_15689_3 1278309.KB907110_gene3171 1.39e-269 743.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria,1XIR6@135619|Oceanospirillales 135619|Oceanospirillales F Xanthine uracil uraA - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease k141_15689_4 1278309.KB907110_gene3172 1.21e-49 163.0 COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,1XI9Z@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase k141_8084_1 412597.AEPN01000023_gene738 1.47e-27 102.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,2PWY3@265|Paracoccus 28211|Alphaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_14267_1 1123487.KB892850_gene305 1.55e-24 102.0 2CPPK@1|root,32SJJ@2|Bacteria,1MZQ2@1224|Proteobacteria,2VU8G@28216|Betaproteobacteria,2KZ8N@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 k141_20606_1 1318628.MARLIPOL_15027 1.26e-74 246.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2183 Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_5931_3 1123514.KB905899_gene1732 3.64e-20 82.4 2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,1SCE5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mitomycin resistance protein mcrB - - - - - - - - - - - Cdd1 k141_15706_1 1283299.AUKG01000001_gene1291 6.23e-06 47.8 COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4CPB7@84995|Rubrobacteria 84995|Rubrobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 k141_15706_2 1122137.AQXF01000005_gene1260 6.07e-87 266.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_22975 - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_3184_1 1056820.KB900630_gene1355 1.45e-50 178.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,2PMTW@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L breast cancer carboxy-terminal domain ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_3184_2 1458357.BG58_07605 6.26e-35 128.0 COG2010@1|root,COG2010@2|Bacteria,1MW1W@1224|Proteobacteria,2WB36@28216|Betaproteobacteria,1KE9J@119060|Burkholderiaceae 28216|Betaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_9371_1 1353528.DT23_17210 1.18e-186 525.0 COG0451@1|root,COG0451@2|Bacteria,1MW8N@1224|Proteobacteria,2TSJB@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM dehydratase - - - - - - - - - - - - Epimerase k141_10836_1 314278.NB231_07492 4.77e-54 198.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales 135613|Chromatiales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA - 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_3835_1 710685.MycrhN_0018 2.38e-61 192.0 COG0680@1|root,COG0680@2|Bacteria,2H4KY@201174|Actinobacteria,23DJJ@1762|Mycobacteriaceae 201174|Actinobacteria C Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - - - - - - - - - - - k141_3835_2 1278309.KB907099_gene2893 1.64e-66 207.0 2CH72@1|root,3179T@2|Bacteria,1QEGH@1224|Proteobacteria,1TB5R@1236|Gammaproteobacteria,1XM1S@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_3835_3 1085623.GNIT_2768 2.31e-18 85.9 COG3572@1|root,COG3572@2|Bacteria,1N0R0@1224|Proteobacteria,1S9DH@1236|Gammaproteobacteria,467K5@72275|Alteromonadaceae 1236|Gammaproteobacteria H Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 k141_3835_4 1278309.KB907099_gene2895 4.89e-103 302.0 2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria,1XKP9@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3833) - - - - - - - - - - - - DUF3833 k141_3835_5 1278309.KB907099_gene2896 2.29e-11 62.8 COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,1RSHH@1236|Gammaproteobacteria,1XIVU@135619|Oceanospirillales 135619|Oceanospirillales S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_21304_1 1288826.MSNKSG1_01458 3.87e-09 56.2 COG3239@1|root,COG3239@2|Bacteria,1R3XI@1224|Proteobacteria,1RRM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_21304_2 1288826.MSNKSG1_01463 2.13e-229 632.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RNYC@1236|Gammaproteobacteria,4685I@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_21304_3 1288826.MSNKSG1_01468 4.12e-274 751.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,465VR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 4.1.1.82 ko:K09459,ko:K10907 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_12922_2 314278.NB231_00770 1.42e-75 233.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales 135613|Chromatiales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_21980_1 90814.KL370891_gene1396 8.31e-84 272.0 COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Type I site-specific restriction-modification system R (restriction) subunit and related helicases - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoEI_R_C,HSDR_N,Helicase_C,ResIII k141_8094_1 1479237.JMLY01000001_gene483 8.53e-194 541.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,4649Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k141_9372_1 1085623.GNIT_2351 6.72e-29 118.0 COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZW9@1236|Gammaproteobacteria,464SJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - GGDEF,Reg_prop,Y_Y_Y k141_10837_1 439496.RBY4I_1883 3.42e-45 155.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria 28211|Alphaproteobacteria E threonine dehydratase tdcB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_10837_2 1294273.roselon_02441 3.06e-24 99.4 COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_17798_1 498211.CJA_0920 2.97e-35 128.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1FFVR@10|Cellvibrio 1236|Gammaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_17798_2 247633.GP2143_17621 4.28e-74 230.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,1J6JE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG3806 Anti-sigma factor - - - - - - - - - - - - Cupin_7 k141_17798_3 1278309.KB907101_gene387 6.07e-150 428.0 28IWY@1|root,2Z8V1@2|Bacteria,1R9PZ@1224|Proteobacteria,1SGUD@1236|Gammaproteobacteria,1XNYE@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_17798_4 1278309.KB907101_gene388 2.82e-145 414.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1RBTP@1224|Proteobacteria,1S2UJ@1236|Gammaproteobacteria,1XJR8@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_17798_5 1278309.KB907101_gene389 2.02e-189 530.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,1RNFV@1236|Gammaproteobacteria,1XIU1@135619|Oceanospirillales 135619|Oceanospirillales E ornithine cyclodeaminase - - 1.5.1.49,4.3.1.12 ko:K01750,ko:K19742 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671,R01246,R01249 RC00135,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_17798_6 1333856.L686_02460 3.98e-268 744.0 COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Na H antiporter - - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_15708_1 56110.Oscil6304_2815 9.24e-28 116.0 COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales 1117|Cyanobacteria O Beta-propeller repeat - - - - - - - - - - - - Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP k141_21981_1 675817.VDA_003173 9.8e-08 52.4 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XTFF@135623|Vibrionales 135623|Vibrionales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yigM - - - - - - - - - - - EamA k141_5932_1 402777.KB235903_gene2440 3.48e-05 45.4 COG0110@1|root,COG0110@2|Bacteria,1G35K@1117|Cyanobacteria,1H98M@1150|Oscillatoriales 1117|Cyanobacteria S Acetyltransferase (Isoleucine patch superfamily) act - - ko:K18234 - - - - ko00000,ko01000,ko01504 - - - Hexapep k141_12363_1 377629.TERTU_2182 1.16e-55 175.0 COG2963@1|root,COG2963@2|Bacteria,1N1CG@1224|Proteobacteria 1224|Proteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_17204_2 1397528.Q671_07845 2.79e-63 197.0 COG5615@1|root,COG5615@2|Bacteria,1N3BK@1224|Proteobacteria,1T0D6@1236|Gammaproteobacteria,1XRQ9@135619|Oceanospirillales 135619|Oceanospirillales S Copper resistance protein D - - - - - - - - - - - - CopD k141_12384_2 631362.Thi970DRAFT_04675 2.45e-33 120.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1WWW9@135613|Chromatiales 135613|Chromatiales L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt - - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T k141_4707_1 305700.B447_01516 1.02e-20 85.9 2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,2KX0T@206389|Rhodocyclales 206389|Rhodocyclales S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 k141_9472_1 1168067.JAGP01000001_gene177 4.47e-81 258.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,4604M@72273|Thiotrichales 72273|Thiotrichales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_17951_1 443152.MDG893_09321 1.97e-48 164.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,4672J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_19972_1 631362.Thi970DRAFT_00495 4.69e-49 178.0 28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,1WW4J@135613|Chromatiales 135613|Chromatiales S Carboxysome shell peptide mid-region - - - - - - - - - - - - CsoS2_M k141_12385_1 565045.NOR51B_61 2.12e-63 207.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5FS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V MacB-like periplasmic core domain VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_5393_2 1485544.JQKP01000017_gene610 1.03e-28 112.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales 28216|Betaproteobacteria I Squalene/phytoene synthase hpnC - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_15097_1 930166.CD58_24025 4.18e-32 116.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA - - - - - - - - - - - Hexapep,Hexapep_2 k141_15097_2 1288826.MSNKSG1_03842 5.11e-33 114.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SGHW@1236|Gammaproteobacteria,4692J@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_15097_3 1288826.MSNKSG1_03847 2.3e-233 645.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,465GE@72275|Alteromonadaceae 1236|Gammaproteobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_1135 ATP-grasp,Epimerase k141_10240_1 1278309.KB907102_gene100 1.3e-171 483.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,1XIQ2@135619|Oceanospirillales 135619|Oceanospirillales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_10240_2 1278309.KB907102_gene99 2.06e-278 771.0 COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria,1XHZ5@135619|Oceanospirillales 135619|Oceanospirillales P TrkA-N domain - - - - - - - - - - - - Ion_trans_2,TrkA_N k141_7473_1 207954.MED92_06383 4.1e-56 189.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XIPI@135619|Oceanospirillales 135619|Oceanospirillales E alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_7473_2 1348114.OM33_16865 1.48e-31 124.0 COG0834@1|root,COG0834@2|Bacteria,1N00T@1224|Proteobacteria,1S223@1236|Gammaproteobacteria,2Q2F0@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_7473_3 1122599.AUGR01000009_gene2423 7.31e-65 221.0 COG2207@1|root,COG3899@1|root,COG2207@2|Bacteria,COG3899@2|Bacteria,1MX23@1224|Proteobacteria,1SYG8@1236|Gammaproteobacteria,1XKV4@135619|Oceanospirillales 135619|Oceanospirillales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_2559_1 396588.Tgr7_1231 2.09e-127 375.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1WWYX@135613|Chromatiales 135613|Chromatiales E TIGRFAM lysine 2,3-aminomutase YodO family protein - - 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM k141_9473_1 1298593.TOL_3205 2.65e-23 95.5 2BN8J@1|root,32GW0@2|Bacteria,1RH74@1224|Proteobacteria,1S7A4@1236|Gammaproteobacteria,1XM4F@135619|Oceanospirillales 135619|Oceanospirillales S LPP20 lipoprotein - - - - - - - - - - - - LPP20 k141_504_2 1218352.B597_003905 2.23e-28 112.0 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1Z0ZB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_14366_1 740709.A10D4_08979 4.53e-33 119.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,2QFYA@267893|Idiomarinaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2062) TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_16508_1 713586.KB900536_gene1812 1.26e-64 211.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales 135613|Chromatiales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_6701_1 1158165.KB898872_gene1134 8.3e-39 152.0 COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1T44K@1236|Gammaproteobacteria,1WXW4@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg k141_6701_2 323848.Nmul_A0338 9.82e-14 68.2 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,3736N@32003|Nitrosomonadales 28216|Betaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_17952_1 1144310.PMI07_006417 3.28e-39 141.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,4B7GY@82115|Rhizobiaceae 28211|Alphaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.67 ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05699,R06366,R08146 RC00047,RC00071,RC00075,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17952_2 991905.SL003B_3945 1.47e-68 222.0 COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_29840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot k141_11642_1 1028800.RG540_CH13710 3.59e-38 144.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria,4BIA7@82115|Rhizobiaceae 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k141_10968_1 1163617.SCD_n00909 1.27e-79 247.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria 28216|Betaproteobacteria F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_6022_1 1415754.JQMK01000002_gene3620 1.95e-61 209.0 COG2133@1|root,COG3266@1|root,COG3299@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG3299@2|Bacteria,1QZBF@1224|Proteobacteria,1T44G@1236|Gammaproteobacteria,4658Q@72275|Alteromonadaceae 1236|Gammaproteobacteria G PA14 - - - - - - - - - - - - PA14,fn3 k141_6022_2 1288826.MSNKSG1_06858 5.72e-29 120.0 COG1215@1|root,COG1215@2|Bacteria,1QXFV@1224|Proteobacteria,1T599@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_6022_3 270374.MELB17_14291 5.81e-218 619.0 2C4I1@1|root,33QND@2|Bacteria,1NT8I@1224|Proteobacteria,1SMMV@1236|Gammaproteobacteria,46AGA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Parallel beta-helix repeats - - - - - - - - - - - - - k141_6022_4 270374.MELB17_14286 2e-27 104.0 COG0110@1|root,COG0110@2|Bacteria,1RDQE@1224|Proteobacteria,1S3RJ@1236|Gammaproteobacteria,466XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (Isoleucine patch superfamily) - - - - - - - - - - - - Hexapep,Hexapep_2 k141_10241_1 391619.PGA1_c23050 9.93e-44 150.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VEXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_10241_2 391616.OA238_c14490 2.18e-29 110.0 COG3828@1|root,COG3828@2|Bacteria,1QWCA@1224|Proteobacteria,2U09A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_14010 - - ko:K09992 - - - - ko00000 - - - ThuA k141_5394_1 1122169.AREN01000010_gene2574 2.62e-97 306.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1JCH1@118969|Legionellales 118969|Legionellales I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain yfcX - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_16509_1 351348.Maqu_2554 1.78e-71 225.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,4650N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_8797_1 1280949.HAD_03615 2.46e-47 174.0 COG1196@1|root,COG1196@2|Bacteria,1RJ96@1224|Proteobacteria 1224|Proteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k141_505_1 1380367.JIBC01000009_gene1565 3.41e-22 96.7 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,3ZWAA@60136|Sulfitobacter 28211|Alphaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor tauR - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_505_2 1400525.JNIU01000001_gene513 5.28e-09 55.8 COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2TTAQ@28211|Alphaproteobacteria,4BRPM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family xsc - 2.3.3.15 ko:K03852 ko00430,map00430 - R05651 RC02903,RC02909 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_4708_1 2340.JV46_19080 3.72e-196 573.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1J8A6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_14367_1 413404.Rmag_0875 1.04e-99 317.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_11643_1 1317124.DW2_03309 5.09e-50 172.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2XMZZ@285107|Thioclava 28211|Alphaproteobacteria EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_17208_1 380358.XALC_1780 5.02e-06 48.1 COG0010@1|root,COG0010@2|Bacteria,1MY4S@1224|Proteobacteria,1S384@1236|Gammaproteobacteria,1X47S@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the arginase family - - - - - - - - - - - - Arginase k141_17208_2 1396418.BATQ01000184_gene2568 1.49e-37 134.0 COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia 74201|Verrucomicrobia S Lipid A Biosynthesis N-terminal domain - - - - - - - - - - - - LAB_N,T2SSG k141_19974_1 640081.Dsui_3189 4.5e-39 145.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KV9G@206389|Rhodocyclales 206389|Rhodocyclales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M k141_21434_1 351348.Maqu_1621 1.67e-30 124.0 COG2133@1|root,COG3266@1|root,COG3299@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG3299@2|Bacteria,1QZBF@1224|Proteobacteria,1T44G@1236|Gammaproteobacteria,4658Q@72275|Alteromonadaceae 1236|Gammaproteobacteria G PA14 - - - - - - - - - - - - PA14,fn3 k141_6023_1 472759.Nhal_2748 1.38e-70 230.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_6023_2 1265313.HRUBRA_00090 8.98e-36 128.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_16511_2 2340.JV46_15440 2.55e-20 89.4 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster dsrL - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,NADH_4Fe-4S,Pyr_redox_2 k141_4709_1 351348.Maqu_3386 7.84e-154 461.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,465D4@72275|Alteromonadaceae 1236|Gammaproteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII k141_14368_1 1278309.KB907099_gene3046 3.65e-62 197.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1XIX0@135619|Oceanospirillales 135619|Oceanospirillales S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_8798_1 765912.Thimo_2698 3.94e-56 198.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1WXJ3@135613|Chromatiales 135613|Chromatiales E PFAM Transglutaminase-like - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_22088_1 1288826.MSNKSG1_02931 1.55e-102 309.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,465H1@72275|Alteromonadaceae 1236|Gammaproteobacteria E 7 transmembrane helices usually fused to an inactive transglutaminase IV02_00930 - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_22088_2 1288826.MSNKSG1_02936 2.95e-180 503.0 COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1SZUE@1236|Gammaproteobacteria,467V0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease k141_3941_1 396588.Tgr7_2136 1.04e-32 117.0 COG4831@1|root,COG4831@2|Bacteria,1NMBS@1224|Proteobacteria,1SHJI@1236|Gammaproteobacteria,1X1V5@135613|Chromatiales 135613|Chromatiales S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_3941_2 2340.JV46_26600 1.53e-40 137.0 COG4831@1|root,COG4831@2|Bacteria,1N4ET@1224|Proteobacteria,1SG6W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_3941_3 2340.JV46_26610 1.01e-41 140.0 COG4831@1|root,COG4831@2|Bacteria,1N55K@1224|Proteobacteria 1224|Proteobacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_3941_4 999141.GME_18018 2.47e-34 133.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XH4B@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_5396_1 388413.ALPR1_16019 7.74e-125 370.0 COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b k141_507_1 2340.JV46_24740 2.33e-11 63.2 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k141_507_2 1163617.SCD_n02930 2.23e-130 378.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria 28216|Betaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k141_19341_1 351348.Maqu_0543 2.38e-23 94.0 COG2063@1|root,COG2063@2|Bacteria 2|Bacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_19341_2 1288826.MSNKSG1_17351 9.79e-65 200.0 2EJFN@1|root,33D6M@2|Bacteria,1NK81@1224|Proteobacteria,1ST3P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19341_3 1288826.MSNKSG1_17356 1.33e-41 142.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S9TM@1236|Gammaproteobacteria,468Q1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_19975_1 2340.JV46_10870 5.16e-125 387.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1J4DR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_16512_1 1122197.ATWI01000011_gene436 2.52e-102 322.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_12388_1 395493.BegalDRAFT_0164 2.13e-38 140.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,4604I@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_12388_2 1215343.B488_03140 0.000103 48.5 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2TUVR@28211|Alphaproteobacteria,4BADR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Colicin V production protein cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V k141_15101_1 1463926.JOCA01000010_gene2240 7.43e-28 112.0 COG1309@1|root,COG1309@2|Bacteria,2IKPS@201174|Actinobacteria 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_5397_1 913325.N799_01740 1.77e-54 178.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1X32R@135614|Xanthomonadales 135614|Xanthomonadales O Part of SUF system involved in inserting iron-sulfur clusters into proteins sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_22089_1 1535422.ND16A_1814 3.44e-111 358.0 COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Parallel beta-helix repeats - - - - - - - - - - - - Cu-oxidase_3 k141_3942_1 488538.SAR116_1593 4.73e-26 108.0 COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,2VC7Z@28211|Alphaproteobacteria,4BQ7V@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G xylanase chitin deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_8799_1 411684.HPDFL43_02445 1.81e-103 316.0 COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria,2U0PC@28211|Alphaproteobacteria,43HR6@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS k141_6024_1 396588.Tgr7_0891 1.61e-152 438.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1WWZ4@135613|Chromatiales 135613|Chromatiales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_6024_2 107636.JQNK01000004_gene826 0.000103 44.3 COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidase, M50 family - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,PqqD k141_10251_1 1288826.MSNKSG1_08808 5.36e-246 686.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_14375_1 1288826.MSNKSG1_12417 6.34e-142 409.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RY35@1236|Gammaproteobacteria,46A6F@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_14375_2 1288826.MSNKSG1_12422 2.82e-194 539.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,464K2@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_18608_2 1382306.JNIM01000001_gene3764 4.64e-96 295.0 COG0277@1|root,COG0277@2|Bacteria,2G8B5@200795|Chloroflexi 200795|Chloroflexi C PFAM FAD linked oxidase domain protein - - - - - - - - - - - - FAD_binding_4 k141_22237_2 498211.CJA_0460 4.87e-85 264.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1FGJN@10|Cellvibrio 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_4837_1 1255043.TVNIR_2716 9.62e-145 423.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_21565_1 697282.Mettu_0042 1.13e-89 279.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XE67@135618|Methylococcales 135618|Methylococcales O Peptidase U32 - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_14503_1 948106.AWZT01000053_gene1576 3.72e-30 113.0 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2VRYW@28216|Betaproteobacteria,1K931@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 k141_14503_2 1535422.ND16A_3954 3.18e-122 362.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria 1236|Gammaproteobacteria O FeS assembly protein SufB sufB GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 k141_626_1 1165841.SULAR_01190 1.06e-126 374.0 COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria 1224|Proteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_626_2 323261.Noc_0881 1.32e-13 70.1 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 k141_8362_1 65093.PCC7418_2895 7.81e-29 123.0 COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria 1117|Cyanobacteria K ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_8943_1 192952.MM_2565 2.84e-70 228.0 COG1180@1|root,arCOG00946@2157|Archaea,2XUB7@28890|Euryarchaeota,2N915@224756|Methanomicrobia 224756|Methanomicrobia C PFAM Radical SAM domain protein pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM k141_8943_2 1382356.JQMP01000001_gene971 9.66e-75 240.0 COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,27XHM@189775|Thermomicrobia 189775|Thermomicrobia F Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - - - - - - - - - - ATP-grasp_4 k141_9631_1 690585.JNNU01000016_gene2698 2.86e-76 234.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,4BBT7@82115|Rhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_9631_2 690585.JNNU01000016_gene2697 2.15e-39 139.0 COG4177@1|root,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,4B7B0@82115|Rhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13226_2 948106.AWZT01000005_gene4503 6.03e-76 241.0 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,2VP9I@28216|Betaproteobacteria,1K2JK@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_13226_5 335283.Neut_2476 3.61e-26 103.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,2WBHY@28216|Betaproteobacteria,3735U@32003|Nitrosomonadales 28216|Betaproteobacteria T Universal stress protein - - - ko:K06149 - - - - ko00000 - - - Usp k141_13226_6 493475.GARC_4428 1.38e-33 119.0 2C7FC@1|root,32S1T@2|Bacteria,1N1DJ@1224|Proteobacteria,1S96F@1236|Gammaproteobacteria,468FD@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13226_8 637389.Acaty_c2281 2.43e-92 291.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales 225057|Acidithiobacillales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_10404_1 765912.Thimo_1636 1.5e-97 288.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales 135613|Chromatiales S Belongs to the WrbA family - - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_10404_2 1396858.Q666_14440 2.54e-45 149.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_15994_1 192952.MM_3274 2.43e-101 308.0 COG1253@1|root,arCOG00626@2157|Archaea,2Y2H2@28890|Euryarchaeota,2NAGU@224756|Methanomicrobia 224756|Methanomicrobia S Domain of unknown function DUF21 - - - - - - - - - - - - DUF21 k141_17339_1 1265503.KB905162_gene3491 8.19e-90 270.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1RPVE@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Spermidine synthase - - - - - - - - - - - - Spermine_synth k141_18764_2 1123261.AXDW01000006_gene2451 6.55e-68 213.0 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1X6G6@135614|Xanthomonadales 135614|Xanthomonadales M Transglycosylase SLT domain - - - - - - - - - - - - SLT k141_18764_3 425104.Ssed_3130 2.95e-27 110.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,2QA8H@267890|Shewanellaceae 1236|Gammaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iUTI89_1310.UTI89_C0210 HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_22238_1 392500.Swoo_1111 1.19e-51 175.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1S1VT@1236|Gammaproteobacteria,2QAAI@267890|Shewanellaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_8944_1 155864.EDL933_0857 8.89e-13 70.5 COG1403@1|root,COG1403@2|Bacteria,1RHFB@1224|Proteobacteria,1S4HW@1236|Gammaproteobacteria,3XQ0M@561|Escherichia 1236|Gammaproteobacteria V Corresponds to locus_tag - - - - - - - - - - - - NinG k141_6176_1 1288826.MSNKSG1_07078 6.3e-56 176.0 COG1024@1|root,COG1024@2|Bacteria 2|Bacteria I Enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 k141_6176_2 1288826.MSNKSG1_07073 4.1e-215 596.0 COG0697@1|root,COG0697@2|Bacteria,1R7CG@1224|Proteobacteria,1S0XU@1236|Gammaproteobacteria,467WV@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_5526_1 1288826.MSNKSG1_10103 1.27e-307 838.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM Nickel-dependent hydrogenase, large subunit hoxH - - - - - - - - - - - NiFeSe_Hases k141_5526_2 1288826.MSNKSG1_10108 3.03e-182 507.0 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,466Y9@72275|Alteromonadaceae 1236|Gammaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit hoxY - - - - - - - - - - - Oxidored_q6 k141_5526_3 1288826.MSNKSG1_10113 1.58e-156 441.0 COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,466U0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B asrB - - ko:K16951 ko00920,ko01120,map00920,map01120 - R00858,R10146 RC00065 ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 k141_6192_3 243277.VC_2125 6.27e-16 75.9 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1XWWS@135623|Vibrionales 135623|Vibrionales N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C k141_8961_1 754476.Q7A_499 7e-101 303.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales 72273|Thiotrichales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_8961_2 1286106.MPL1_11980 1.98e-136 400.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,460DY@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_2715_1 42565.FP66_08770 3.61e-63 203.0 COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,1RQHJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate fbaB GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640 DeoC k141_3471_1 375286.mma_0614 1.16e-33 122.0 COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VT7Q@28216|Betaproteobacteria,47777@75682|Oxalobacteraceae 28216|Betaproteobacteria K Transcriptional regulator nsrR - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 k141_19468_1 880074.BARVI_11390 1.49e-08 56.2 COG2076@1|root,COG2076@2|Bacteria 2|Bacteria P Multidrug Resistance protein arnE - - ko:K12962 ko01503,map01503 M00721 - - ko00000,ko00001,ko00002,ko01005,ko02000 2.A.7.22 - - EamA,Multi_Drug_Res k141_19468_2 425104.Ssed_0920 1.4e-17 80.1 COG2076@1|root,COG2076@2|Bacteria,1N7ZX@1224|Proteobacteria,1SCDW@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane arnF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K12963 ko01503,map01503 M00721 - - ko00000,ko00001,ko00002,ko01005 2.A.7 - iECUMN_1333.ECUMN_2601,iSF_1195.SF2337,iS_1188.S2471 EamA,Multi_Drug_Res k141_20041_1 713586.KB900536_gene1773 8.23e-67 217.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1WX1N@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_17350_1 1079460.ATTQ01000018_gene4607 2.18e-25 110.0 COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R754@1224|Proteobacteria,2U48Q@28211|Alphaproteobacteria,4BCD9@82115|Rhizobiaceae 28211|Alphaproteobacteria T GGDEF domain - - - - - - - - - - - - 5TM-5TMR_LYT,GGDEF,PAS_4,PAS_7 k141_16652_1 211165.AJLN01000131_gene3642 6.12e-89 278.0 2DB9X@1|root,2Z7ZS@2|Bacteria,1G4IX@1117|Cyanobacteria,1JGT5@1189|Stigonemataceae 1117|Cyanobacteria S Protein of unknown function (DUF3445) - - 1.14.13.238 ko:K22342 - - - - ko00000,ko01000 - - - DUF3445 k141_16652_2 1137799.GZ78_24505 4.12e-34 123.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_18778_1 1045855.DSC_10680 1.06e-21 89.4 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1X7C1@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_21584_1 1198452.Jab_2c02780 4.83e-74 234.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VKIQ@28216|Betaproteobacteria,472K4@75682|Oxalobacteraceae 28216|Betaproteobacteria U AAA domain exeA2 - - ko:K02450,ko:K12283 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 k141_10436_1 1123392.AQWL01000005_gene2862 1.27e-05 44.7 COG2920@1|root,COG2920@2|Bacteria,1N6BZ@1224|Proteobacteria,2WCAJ@28216|Betaproteobacteria,1KTBU@119069|Hydrogenophilales 119069|Hydrogenophilales P DsrC like protein - - - - - - - - - - - - DsrC k141_10436_2 95619.PM1_0208390 9.32e-55 194.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_5551_1 1288826.MSNKSG1_09058 1.2e-225 657.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_6810_2 1288826.MSNKSG1_15586 9.38e-91 273.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RZ9D@1236|Gammaproteobacteria,469RA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Radical SAM - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM k141_2716_1 1122134.KB893650_gene502 8.63e-76 229.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XK83@135619|Oceanospirillales 135619|Oceanospirillales S EVE domain - - - - - - - - - - - - EVE k141_11144_1 652103.Rpdx1_0364 8.12e-73 231.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,3JRD6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 k141_6195_1 1121405.dsmv_1079 1.58e-41 143.0 COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2WJ7N@28221|Deltaproteobacteria,2MIQK@213118|Desulfobacterales 28221|Deltaproteobacteria C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrom_CIII,Cytochrome_C7 k141_14525_1 207954.MED92_09541 2.24e-201 581.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RYFX@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF k141_14525_2 1278309.KB907099_gene2587 1.35e-218 605.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,1RMCE@1236|Gammaproteobacteria,1XINK@135619|Oceanospirillales 135619|Oceanospirillales C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase k141_14525_3 521719.ATXQ01000002_gene2541 2.14e-129 371.0 COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,1YFVS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase ycgF - - - - - - - - - - - EAL k141_17351_1 1123368.AUIS01000007_gene2676 9.55e-76 254.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,2NCRZ@225057|Acidithiobacillales 225057|Acidithiobacillales S Uncharacterized protein conserved in bacteria (DUF2309) - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_9649_1 1122194.AUHU01000020_gene3494 1.63e-86 270.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_9649_2 228410.NE2459 1.26e-19 89.4 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,3733Y@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 - - - BPL_C,BPL_LplA_LipB,Pan_kinase k141_10437_1 1216966.BAUC01000034_gene3086 2.41e-31 120.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_643_1 583355.Caka_2418 8.84e-157 446.0 COG1089@1|root,COG1089@2|Bacteria,46SH0@74201|Verrucomicrobia,3K752@414999|Opitutae 414999|Opitutae M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k141_11749_1 572477.Alvin_2073 3.74e-06 47.4 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1WXF4@135613|Chromatiales 135613|Chromatiales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_11749_2 1117647.M5M_12365 1.4e-26 108.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1J4FR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein containing LysM domain lysM - - - - - - - - - - - LysM k141_2717_1 1454004.AW11_02656 2.11e-65 208.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria,1KQTD@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J RNA pseudouridylate synthase rluA - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_13935_1 525898.Sdel_0913 1.45e-30 127.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YNJH@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T His Kinase A (phospho-acceptor) domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - HATPase_c,HisKA,Hpt,PAS_9,Response_reg k141_4858_1 1288826.MSNKSG1_16416 8.54e-219 607.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,465ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0097159,GO:0097367,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - iB21_1397.B21_01132,iECBD_1354.ECBD_2473,iECB_1328.ECB_01124,iECD_1391.ECD_01124,iECO111_1330.ECO111_1474,iECO26_1355.ECO26_1643,iEcHS_1320.EcHS_A1246,iEcolC_1368.EcolC_2477,iSBO_1134.SBO_1915,iSSON_1240.SSON_1144,iSbBS512_1146.SbBS512_E1304,iUMNK88_1353.UMNK88_1456 ABC_tran,TOBE_2 k141_4858_2 1288826.MSNKSG1_16411 1.07e-263 721.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_4858_3 1288826.MSNKSG1_16406 3.04e-96 296.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_2 k141_14526_1 1260251.SPISAL_05830 3.77e-62 210.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales 135613|Chromatiales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_5552_1 1278309.KB907104_gene969 1.48e-131 398.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_6196_1 595537.Varpa_5572 6.1e-07 53.1 2DHD4@1|root,32U92@2|Bacteria,1N29H@1224|Proteobacteria,2VU9F@28216|Betaproteobacteria,4AEY8@80864|Comamonadaceae 28216|Betaproteobacteria S LTXXQ motif family protein - - - - - - - - - - - - LTXXQ,Metal_resist k141_6196_2 1286631.X805_12600 4.4e-08 55.8 2DHD4@1|root,32U92@2|Bacteria,1N29H@1224|Proteobacteria,2VU9F@28216|Betaproteobacteria,1KMG4@119065|unclassified Burkholderiales 28216|Betaproteobacteria S LTXXQ motif family protein - - - - - - - - - - - - LTXXQ,Metal_resist k141_644_1 935948.KE386495_gene1346 7.4e-05 49.3 28H9V@1|root,2Z7MH@2|Bacteria,1UFFG@1239|Firmicutes,24AMI@186801|Clostridia,42I8D@68295|Thermoanaerobacterales 186801|Clostridia - - - - - - - - - - - - - - - k141_11146_1 1278309.KB907108_gene1628 2.51e-105 319.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1XHN0@135619|Oceanospirillales 135619|Oceanospirillales P COG3639 ABC-type phosphate phosphonate transport system, permease component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - - k141_21585_1 261292.Nit79A3_0044 2.97e-65 214.0 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,2VNRP@28216|Betaproteobacteria,372MR@32003|Nitrosomonadales 28216|Betaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,DUF2934,OSCP k141_21585_2 525897.Dbac_0947 8.54e-35 120.0 COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WQ4V@28221|Deltaproteobacteria,2MCKY@213115|Desulfovibrionales 28221|Deltaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_19469_1 1439940.BAY1663_00845 2.89e-37 147.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_19469_2 1333856.L686_16965 7.22e-15 74.7 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1Z1KH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,CbiA,GATase_3 k141_4859_1 2340.JV46_20340 6.53e-94 298.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1J62R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_7599_1 533247.CRD_02360 1.51e-62 197.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1HM7U@1161|Nostocales 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_7599_2 713587.THITH_04180 6.72e-72 222.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1WZ06@135613|Chromatiales 135613|Chromatiales S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 k141_14016_1 1237149.C900_03719 5.77e-50 171.0 2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,47PFJ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 k141_8422_1 1278309.KB907101_gene454 1.57e-112 344.0 COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,1RPF4@1236|Gammaproteobacteria,1XRH8@135619|Oceanospirillales 135619|Oceanospirillales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_8422_2 1278309.KB907101_gene453 2.47e-97 291.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,1XM9Y@135619|Oceanospirillales 135619|Oceanospirillales S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_8422_3 1278309.KB907101_gene452 6.04e-315 877.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1XHU5@135619|Oceanospirillales 135619|Oceanospirillales E COG1305 Transglutaminase-like enzymes - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_8422_4 1278309.KB907101_gene451 5.37e-169 480.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1XJKH@135619|Oceanospirillales 135619|Oceanospirillales S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_8422_5 1278309.KB907101_gene450 8.33e-109 320.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1XI8W@135619|Oceanospirillales 135619|Oceanospirillales S ATPase, AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_13324_2 1206731.BAGB01000157_gene5868 2.54e-59 192.0 COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria,4G9PR@85025|Nocardiaceae 201174|Actinobacteria Q Thiopurine S-methyltransferase (TPMT) - - - - - - - - - - - - Methyltransf_25,TPMT k141_13324_3 857087.Metme_2119 1.07e-115 348.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,1T3H9@1236|Gammaproteobacteria,1XDWD@135618|Methylococcales 135618|Methylococcales H Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_13324_4 1210046.B277_15594 2.07e-18 82.8 COG0500@1|root,COG2226@2|Bacteria,2IHPD@201174|Actinobacteria,4FGM2@85021|Intrasporangiaceae 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25 k141_11931_1 1288826.MSNKSG1_11967 2.02e-235 657.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,4663U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG4993 Glucose dehydrogenase pedH - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 k141_3551_2 768671.ThimaDRAFT_0175 8.35e-23 93.6 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1SEBT@1236|Gammaproteobacteria,1WZ6I@135613|Chromatiales 135613|Chromatiales C TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_5668_1 1182590.BN5_01411 2.79e-82 267.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1YEEV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 PEP-utilizers,PEP-utilizers_C,PPDK_N k141_759_2 580332.Slit_1284 7.41e-13 68.9 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,44V76@713636|Nitrosomonadales 28216|Betaproteobacteria L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_6326_1 1042377.AFPJ01000023_gene657 4.06e-76 259.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_21026_1 207954.MED92_00375 1.3e-198 560.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1XITD@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_14723_1 1288826.MSNKSG1_06008 2.02e-79 255.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_14723_2 1288826.MSNKSG1_06003 2.99e-85 257.0 COG3743@1|root,COG3743@2|Bacteria,1NJH4@1224|Proteobacteria,1SS05@1236|Gammaproteobacteria,46C4Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S Helix-hairpin-helix DNA-binding motif class 1 - - - - - - - - - - - - HHH_5 k141_14723_4 1288826.MSNKSG1_05993 2.11e-224 626.0 COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,4648Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_13325_1 859657.RPSI07_mp0939 6.95e-58 191.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria 28216|Betaproteobacteria O Xanthine and CO dehydrogenases maturation factor XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_13325_2 279714.FuraDRAFT_1513 2.96e-23 96.3 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria 28216|Betaproteobacteria S Molybdopterin-guanine dinucleotide biosynthesis protein MobA - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_11932_1 359.CN09_21005 1.21e-13 70.1 COG1172@1|root,COG1172@2|Bacteria,1MUDF@1224|Proteobacteria,2U4K2@28211|Alphaproteobacteria,4B86Z@82115|Rhizobiaceae 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_11932_2 1353537.TP2_15295 8.01e-119 345.0 COG1129@1|root,COG1129@2|Bacteria,1MW4I@1224|Proteobacteria,2TY4S@28211|Alphaproteobacteria,2XP4Y@285107|Thioclava 28211|Alphaproteobacteria G ABC transporter, ATP-binding protein - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_8424_1 1288826.MSNKSG1_01963 7.99e-117 343.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RNHA@1236|Gammaproteobacteria,46CTQ@72275|Alteromonadaceae 1236|Gammaproteobacteria V HlyD membrane-fusion protein of T1SS emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_17466_1 1128912.GMES_1216 4.23e-20 83.2 COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,1S5X5@1236|Gammaproteobacteria,467HX@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Peptidase S24-like umuD GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009355,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 - ko:K03503 - - - - ko00000,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_17466_2 1120953.AUBH01000001_gene911 1.93e-11 65.9 COG2135@1|root,COG2135@2|Bacteria,1RCCC@1224|Proteobacteria,1S39B@1236|Gammaproteobacteria,46737@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k141_5670_1 1122599.AUGR01000004_gene2098 7.73e-38 136.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XH2T@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_16796_1 472759.Nhal_2204 2.25e-130 386.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales 135613|Chromatiales S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_16796_2 243233.MCA0063 6.2e-58 194.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales 135618|Methylococcales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_18887_1 1278309.KB907106_gene1272 2.89e-229 639.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1XHJI@135619|Oceanospirillales 135619|Oceanospirillales H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_18887_2 1278309.KB907106_gene1271 6.84e-178 499.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1XIHP@135619|Oceanospirillales 135619|Oceanospirillales O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_18887_3 1278309.KB907106_gene1270 1.5e-65 202.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1XKFY@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the HSP15 family hslR - - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_18887_4 1278309.KB907106_gene1269 5.59e-138 392.0 COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,1T1GC@1236|Gammaproteobacteria,1XRU5@135619|Oceanospirillales 135619|Oceanospirillales S hydrolase - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_18887_5 1278309.KB907106_gene1268 4.67e-89 264.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1XJ93@135619|Oceanospirillales 135619|Oceanospirillales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudE - - ko:K08312 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_3552_1 1278309.KB907101_gene494 1.34e-76 248.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,1XIKP@135619|Oceanospirillales 135619|Oceanospirillales E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 k141_3552_2 1278309.KB907101_gene493 4.37e-89 270.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1XHN5@135619|Oceanospirillales 135619|Oceanospirillales S Iron-sulfur cluster-binding domain pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_21027_1 1313421.JHBV01000013_gene3789 2.7e-17 80.9 COG1595@1|root,COG1595@2|Bacteria,4NM7R@976|Bacteroidetes,1IYKQ@117747|Sphingobacteriia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_21027_2 1122176.KB903542_gene405 5.51e-27 102.0 COG1011@1|root,COG1011@2|Bacteria 2|Bacteria S phosphatase activity - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_4235_1 1122135.KB893135_gene973 1.23e-189 537.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_4235_2 1278309.KB907101_gene786 3.22e-158 450.0 COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,1RXYN@1236|Gammaproteobacteria,1XJ3H@135619|Oceanospirillales 135619|Oceanospirillales C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM k141_4235_3 1278309.KB907101_gene785 1.02e-125 363.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales 135619|Oceanospirillales L TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_11933_1 207954.MED92_06558 2.12e-57 193.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1XIAH@135619|Oceanospirillales 135619|Oceanospirillales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_6327_1 1288826.MSNKSG1_10758 8.46e-14 72.8 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,464HR@72275|Alteromonadaceae 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_5671_1 243365.CV_4056 2.57e-51 168.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,2KPV0@206351|Neisseriales 206351|Neisseriales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_2848_1 1007096.BAGW01000002_gene1260 3.23e-10 64.3 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,2N88T@216572|Oscillospiraceae 186801|Clostridia T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_7753_1 1273103.NM10_08658 1.22e-26 111.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H2CV@909932|Negativicutes 909932|Negativicutes I NAD binding domain protein glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_762_1 279714.FuraDRAFT_0704 1.8e-67 216.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KPE8@206351|Neisseriales 206351|Neisseriales E chorismate mutase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_3553_1 1123376.AUIU01000014_gene566 4.31e-18 89.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,3J0Y7@40117|Nitrospirae 40117|Nitrospirae P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N k141_2150_1 306281.AJLK01000086_gene2690 0.000361 42.7 COG3408@1|root,COG3408@2|Bacteria,1G2UV@1117|Cyanobacteria,1JI34@1189|Stigonemataceae 1117|Cyanobacteria G Alkaline and neutral invertase lim17 - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_100 k141_2150_2 765912.Thimo_1130 4.5e-43 151.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1WXVN@135613|Chromatiales 135613|Chromatiales G PfkB domain protein - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_18888_1 1304275.C41B8_02807 6.03e-114 342.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_11934_1 713586.KB900536_gene2020 5.92e-35 129.0 COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,1S6IK@1236|Gammaproteobacteria,1WZ86@135613|Chromatiales 135613|Chromatiales S Pfam:DUF162 - - - ko:K00782 - - - - ko00000 - - - LUD_dom k141_14019_1 1380367.JIBC01000007_gene1075 3.95e-57 194.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,3ZVRW@60136|Sulfitobacter 28211|Alphaproteobacteria C Domain of unknown function (DUF4445) nqrF - - - - - - - - - - - DUF4445,Fer2 k141_14019_2 391589.RGAI101_2965 2.34e-35 134.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,2P1QF@2433|Roseobacter 28211|Alphaproteobacteria C metal-binding protein nqrF - - - - - - - - - - - DUF4445,Fer2 k141_17467_1 395493.BegalDRAFT_1371 5.19e-15 75.1 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,460I2@72273|Thiotrichales 72273|Thiotrichales T diguanylate cyclase (GGDEF) domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS_9 k141_17467_2 1163617.SCD_n01692 7.26e-74 233.0 COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 k141_4931_1 1288826.MSNKSG1_13562 0.0 1874.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_2849_2 406124.ACPC01000018_gene2709 2.63e-05 45.4 COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_9816_1 768671.ThimaDRAFT_3850 1.01e-13 81.6 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1S2MU@1236|Gammaproteobacteria,1X0Y2@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase with PAS PAC sensor - - - - - - - - - - - - GGDEF,PAS k141_8425_1 1168065.DOK_19170 1.97e-128 388.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1J5CT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase/oxoprolinase hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_16797_1 1218352.B597_004250 4.2e-17 78.2 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1Z2BU@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_16797_2 768671.ThimaDRAFT_3673 1.39e-141 410.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales 135613|Chromatiales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_7754_1 1122194.AUHU01000005_gene963 1.02e-28 119.0 COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1T315@1236|Gammaproteobacteria,46AA9@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - AAA_16,GAF,GGDEF,Pkinase k141_15424_1 1232683.ADIMK_0479 7.78e-115 342.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,469CH@72275|Alteromonadaceae 1236|Gammaproteobacteria U Type II secretion system (T2SS), protein F tadB - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_15424_2 1042375.AFPL01000008_gene3328 1.78e-89 277.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1RTD3@1236|Gammaproteobacteria,468ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretion system (T2SS), protein F tadC - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_9125_1 866546.EPY52982 1.96e-09 64.7 COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3QKI5@4890|Ascomycota,3MDBN@451866|Taphrinomycotina 4751|Fungi T cAMP-dependent protein kinase regulatory subunit Cgs1 PKAR GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480 - ko:K04739 ko04910,map04910 - - - ko00000,ko00001 - - - RIIa,cNMP_binding k141_6328_1 1278309.KB907101_gene464 1.45e-124 365.0 COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,1RQ5G@1236|Gammaproteobacteria,1XIIK@135619|Oceanospirillales 135619|Oceanospirillales E Periplasmic binding protein - - - - - - - - - - - - Peripla_BP_6 k141_6328_2 1278309.KB907101_gene463 5.82e-25 101.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,1XHEM@135619|Oceanospirillales 135619|Oceanospirillales C Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,Lactonase k141_7782_1 1278309.KB907105_gene1538 3.3e-255 714.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1XIID@135619|Oceanospirillales 135619|Oceanospirillales O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA - - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_7782_2 322710.Avin_40350 6.48e-62 191.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Ferredoxin, 2Fe-2S type, ISC system fdx - - ko:K04755 - - - - ko00000 - - - Fer2 k141_7782_3 1278309.KB907105_gene1540 4.72e-32 111.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,1XMAV@135619|Oceanospirillales 135619|Oceanospirillales S Iron-sulphur cluster assembly - - - - - - - - - - - - Fe-S_assembly k141_784_1 1123401.JHYQ01000020_gene943 1.29e-84 264.0 COG2207@1|root,COG2207@2|Bacteria,1N8IV@1224|Proteobacteria,1SD2J@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - HTH_18,SnoaL_2 k141_784_2 1145276.T479_10835 3.36e-11 66.6 COG0500@1|root,COG2226@2|Bacteria,1V5IF@1239|Firmicutes,4HHR9@91061|Bacilli,3IZB1@400634|Lysinibacillus 91061|Bacilli H Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_11 k141_3578_1 243233.MCA0071 3.07e-20 85.5 COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales 135618|Methylococcales S pfam ammecr1 - - - - - - - - - - - - AMMECR1 k141_3578_4 626887.J057_13006 1.88e-144 417.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,46BQ5@72275|Alteromonadaceae 1236|Gammaproteobacteria U Cation efflux family catA - - - - - - - - - - - Cation_efflux,ZT_dimer k141_14040_1 1288826.MSNKSG1_06458 3.91e-126 369.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,465ZV@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_14040_2 1288826.MSNKSG1_06463 1.01e-140 399.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S6WG@1236|Gammaproteobacteria,46DNU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA k141_14040_3 1288826.MSNKSG1_06468 0.0 1129.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4647U@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_9145_1 349521.HCH_02826 2.13e-121 351.0 COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,1RRYE@1236|Gammaproteobacteria,1XJAB@135619|Oceanospirillales 135619|Oceanospirillales Q dienelactone hydrolase - - - - - - - - - - - - DLH k141_9145_2 1278309.KB907100_gene1960 1.41e-111 325.0 COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,1XK5C@135619|Oceanospirillales 135619|Oceanospirillales O 2OG-Fe(II) oxygenase - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3 k141_9145_3 1278309.KB907100_gene1961 5.62e-104 303.0 COG1414@1|root,COG1414@2|Bacteria,1NMZV@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - - k141_9145_5 1278309.KB907100_gene1963 5.26e-58 180.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XM24@135619|Oceanospirillales 135619|Oceanospirillales C COG3245 Cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 k141_9145_6 1278309.KB907100_gene1964 2.24e-185 520.0 COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,1XHZ9@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_9145_7 1122599.AUGR01000001_gene249 4.44e-138 395.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,1XH6A@135619|Oceanospirillales 135619|Oceanospirillales N MotA TolQ ExbB proton channel - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_20334_1 713586.KB900536_gene984 1.77e-196 557.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales 135613|Chromatiales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_10549_1 1288826.MSNKSG1_16526 0.0 919.0 COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,465G6@72275|Alteromonadaceae 1236|Gammaproteobacteria C conserved protein containing a ferredoxin-like domain lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom k141_10549_2 1288826.MSNKSG1_16521 3.68e-192 534.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,466H0@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0247 Fe-S oxidoreductase lutA - - ko:K18928 - - - - ko00000 - - - CCG k141_10549_3 1288826.MSNKSG1_16516 6.43e-158 446.0 COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,465KR@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional pdhR - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_17488_2 1158182.KB905020_gene2097 3.12e-35 132.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXMA@135613|Chromatiales 135613|Chromatiales T Chemotaxis sensory transducer - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_12638_1 103733.JNYO01000022_gene6881 4.32e-25 108.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_16227_3 1288826.MSNKSG1_14687 1.16e-302 828.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RXC9@1236|Gammaproteobacteria 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - GGDEF,PAS_3 k141_16227_4 1288826.MSNKSG1_14682 6.89e-263 731.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,463YF@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components atmA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_7915_1 381666.PHG091 3.46e-100 304.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,1K6S4@119060|Burkholderiaceae 28216|Betaproteobacteria C Nickel-dependent hydrogenase hoxH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 ko:K00436 - - R00700 - ko00000,ko01000 - - - NiFeSe_Hases k141_7915_2 350058.Mvan_4112 2.4e-10 59.3 COG0680@1|root,COG0680@2|Bacteria,2H4KY@201174|Actinobacteria,23DJJ@1762|Mycobacteriaceae 201174|Actinobacteria C Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - - - - - - - - - - - k141_7189_1 1390370.O203_14850 2.24e-08 60.8 COG2207@1|root,COG2207@2|Bacteria,1RA7U@1224|Proteobacteria,1S2Q5@1236|Gammaproteobacteria,1YDIB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K AraC-binding-like domain benR - - - - - - - - - - - AraC_binding_2,HTH_18 k141_5089_1 765912.Thimo_2646 1.85e-61 204.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1WWQD@135613|Chromatiales 135613|Chromatiales H Belongs to the folylpolyglutamate synthase family - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M k141_18354_1 765911.Thivi_3139 5.56e-36 125.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1WYK5@135613|Chromatiales 135613|Chromatiales S PFAM Sulphur oxidation protein SoxZ - - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ k141_18354_2 768671.ThimaDRAFT_0728 3.57e-49 162.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1WXZY@135613|Chromatiales 135613|Chromatiales S Sulfur oxidation protein SoxY - - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_18354_3 1121403.AUCV01000012_gene4094 3.47e-63 211.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales 28221|Deltaproteobacteria T response regulator receiver - - - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_8595_1 1123368.AUIS01000009_gene2449 1.03e-103 316.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,2NCP1@225057|Acidithiobacillales 225057|Acidithiobacillales S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_8595_2 396588.Tgr7_3240 1.83e-162 460.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales 135613|Chromatiales C PFAM Phosphoribulokinase uridine kinase - - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_19725_1 1454202.PPBDW_140160___1 1.56e-06 51.6 2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19725_2 1278309.KB907099_gene2485 3.23e-54 172.0 COG1522@1|root,COG1522@2|Bacteria,1RD38@1224|Proteobacteria,1S6Q6@1236|Gammaproteobacteria,1XKAS@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_4430_1 1177181.T9A_00667 8.38e-94 285.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XI08@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_4430_2 765913.ThidrDRAFT_1680 3.62e-11 63.9 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12094_2 1038859.AXAU01000007_gene5742 6.79e-58 191.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,3JVCB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Thiosulfate-oxidizing multienzyme system protein SoxA MA20_22830 - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - k141_3729_1 629265.PMA4326_19605 3.42e-79 244.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1Z9IH@136849|Pseudomonas syringae group 1236|Gammaproteobacteria H Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR2 - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_17659_1 443152.MDG893_07670 8.77e-113 327.0 COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,1SZ2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E (ABC) transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_17659_2 443152.MDG893_07665 7.69e-130 372.0 COG1309@1|root,COG1309@2|Bacteria,1RCC8@1224|Proteobacteria,1SG0S@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_928_2 380358.XALC_0633 3.51e-32 116.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1X6W7@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_11420_1 187272.Mlg_1243 5.48e-84 260.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales 135613|Chromatiales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_2290_2 595537.Varpa_2180 2.58e-34 132.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,4ABTG@80864|Comamonadaceae 28216|Betaproteobacteria M Nlpbdapx family lipoprotein nlpB - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_21858_2 1286170.RORB6_00140 2.4e-49 162.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 k141_19740_1 1123368.AUIS01000026_gene1449 9.24e-170 491.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2NBZC@225057|Acidithiobacillales 225057|Acidithiobacillales JKL Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_3747_2 1449351.RISW2_16425 1.32e-85 261.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,4KNBT@93682|Roseivivax 28211|Alphaproteobacteria C Zinc-binding dehydrogenase qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_16977_1 1278309.KB907102_gene193 1.8e-103 300.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1XJSJ@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_20498_1 1041826.FCOL_03680 1.31e-61 196.0 COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,2NVS1@237|Flavobacterium 976|Bacteroidetes P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_12107_1 396588.Tgr7_0968 1.46e-96 302.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales 135613|Chromatiales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_12107_2 385682.AFSL01000041_gene300 1e-06 49.3 COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,2FN4T@200643|Bacteroidia,3XJBJ@558415|Marinilabiliaceae 976|Bacteroidetes P Ferric uptake regulator family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_1648_1 377629.TERTU_4124 7.76e-115 343.0 2DBH4@1|root,2Z97J@2|Bacteria,1R6JR@1224|Proteobacteria,1RS6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17682_1 314292.VAS14_19786 8.94e-83 246.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XSDR@135623|Vibrionales 135623|Vibrionales J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_17682_2 523791.Kkor_0661 1.11e-61 199.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,1XS83@135619|Oceanospirillales 135619|Oceanospirillales S Serine aminopeptidase, S33 - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4 k141_17682_3 76114.ebB118 3.69e-05 43.5 COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,2KWNM@206389|Rhodocyclales 206389|Rhodocyclales C ferredoxin - - - - - - - - - - - - 2Fe-2S_thioredx k141_2291_1 713587.THITH_02745 1.15e-50 176.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1WX4Z@135613|Chromatiales 135613|Chromatiales S AI-2E family transporter - - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_9268_1 1046724.KB889952_gene2065 1.77e-51 165.0 2CGTM@1|root,32S4J@2|Bacteria,1N432@1224|Proteobacteria,1SANC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9268_2 1046724.KB889952_gene2064 3.6e-127 364.0 COG2267@1|root,COG2267@2|Bacteria,1NB9Y@1224|Proteobacteria,1SEKV@1236|Gammaproteobacteria,46C2Y@72275|Alteromonadaceae 1236|Gammaproteobacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - - k141_10728_1 314264.ROS217_02205 8.42e-155 459.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TUTB@28211|Alphaproteobacteria,46PK8@74030|Roseovarius 28211|Alphaproteobacteria H COG0665 Glycine D-amino acid oxidases (deaminating) dmgdh5 - 1.5.8.4 ko:K00315 ko00260,ko01100,map00260,map01100 - R01565 RC00181 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C k141_12108_2 252305.OB2597_03749 1.03e-13 70.9 COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,2PEAQ@252301|Oceanicola 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TPR_21 k141_930_1 1131553.JIBI01000001_gene1411 2.97e-65 224.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,373W6@32003|Nitrosomonadales 28216|Betaproteobacteria I Transmembrane secretion effector aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - Acyltransferase,MFS_1 k141_222_1 1288826.MSNKSG1_15172 3.27e-40 137.0 COG0847@1|root,COG0847@2|Bacteria,1RHD8@1224|Proteobacteria,1SBBK@1236|Gammaproteobacteria,467DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - RNase_T k141_222_4 1288826.MSNKSG1_15162 4.79e-58 179.0 2DPB9@1|root,331CN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_222_5 1288826.MSNKSG1_15157 1.24e-79 237.0 COG0745@1|root,COG0745@2|Bacteria,1RETP@1224|Proteobacteria,1S84I@1236|Gammaproteobacteria,46BIG@72275|Alteromonadaceae 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_222_6 1288826.MSNKSG1_15152 1.12e-114 330.0 2ESW7@1|root,33KEK@2|Bacteria,1NIB4@1224|Proteobacteria,1SI0U@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_222_7 1288826.MSNKSG1_15147 0.0 1648.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4667H@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_7,TPR_8 k141_9953_1 686578.AFFX01000011_gene2673 3.21e-68 223.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_9953_2 1120931.KB893930_gene1629 4.74e-44 157.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1Y7M4@135625|Pasteurellales 135625|Pasteurellales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_18374_1 1288826.MSNKSG1_00271 1.03e-147 423.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,4647G@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1448 Aspartate tyrosine aromatic aminotransferase phhC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_18374_2 225937.HP15_859 1.48e-254 733.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_9269_1 857087.Metme_4039 6.17e-55 174.0 COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,1S5V4@1236|Gammaproteobacteria,1XFEY@135618|Methylococcales 135618|Methylococcales L HNH nucleases - - - - - - - - - - - - HNH k141_2292_1 857087.Metme_0613 3.18e-65 218.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GAF_2,GGDEF k141_20499_1 998674.ATTE01000001_gene2015 8.61e-93 296.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46039@72273|Thiotrichales 72273|Thiotrichales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) - - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_9954_1 1286093.C266_04434 8.64e-58 202.0 COG0508@1|root,COG1643@1|root,COG0508@2|Bacteria,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,1K087@119060|Burkholderiaceae 28216|Betaproteobacteria L Atp-dependent helicase hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_19742_1 1305735.JAFT01000005_gene2837 5.74e-66 221.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2PD1Q@252301|Oceanicola 28211|Alphaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_18375_1 998674.ATTE01000001_gene3831 2.25e-73 236.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,45ZVV@72273|Thiotrichales 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_21859_1 113355.CM001775_gene1170 2.02e-42 149.0 COG0057@1|root,COG0057@2|Bacteria,1G0ZV@1117|Cyanobacteria 1117|Cyanobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap3 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_21859_2 511062.GU3_02280 2.9e-28 111.0 COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc k141_931_2 243233.MCA2834 8.94e-60 196.0 COG2014@1|root,COG2014@2|Bacteria,1R804@1224|Proteobacteria,1S3DP@1236|Gammaproteobacteria,1XE15@135618|Methylococcales 135618|Methylococcales S Putative heavy-metal chelation - - - ko:K09138 - - - - ko00000 - - - DUF364,DUF4213 k141_16979_2 1208321.D104_08430 4.87e-58 191.0 COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1 k141_3748_1 1288826.MSNKSG1_17945 1.36e-89 275.0 COG0457@1|root,COG0457@2|Bacteria,1N8YE@1224|Proteobacteria,1RTI2@1236|Gammaproteobacteria,4699R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - ko:K12284 - - - - ko00000,ko02044 - - - TPR_16 k141_7946_1 686340.Metal_2098 6.17e-42 149.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1XDIV@135618|Methylococcales 135618|Methylococcales F Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_16242_1 1278309.KB907101_gene586 4.61e-54 180.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,1XID3@135619|Oceanospirillales 135619|Oceanospirillales C carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_16242_2 1278309.KB907101_gene587 1.21e-80 254.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RNHN@1236|Gammaproteobacteria,1XI9J@135619|Oceanospirillales 135619|Oceanospirillales I AMP-binding enzyme C-terminal domain - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_17683_1 1255043.TVNIR_1034 1.16e-106 333.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1WX1D@135613|Chromatiales 135613|Chromatiales I acyl-CoA dehydrogenase - - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_6475_1 1278309.KB907100_gene2028 3.16e-23 92.4 2CEPM@1|root,33NPI@2|Bacteria,1NJ0A@1224|Proteobacteria,1SHN3@1236|Gammaproteobacteria,1XMRV@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6475_2 1278309.KB907100_gene2029 3.81e-182 510.0 COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,1RQ7J@1236|Gammaproteobacteria,1XKT4@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1649_2 643867.Ftrac_2326 1.38e-52 173.0 2EIZG@1|root,33CQP@2|Bacteria,4P8HW@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_20500_1 3988.XP_002536358.1 1.77e-52 180.0 COG0324@1|root,KOG1384@2759|Eukaryota 2759|Eukaryota J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 - - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - Band_7,GTP-bdg_M,GTP-bdg_N,IPPT,MMR_HSR1 k141_14191_1 314345.SPV1_08071 2.33e-50 171.0 COG1985@1|root,COG1985@2|Bacteria,1RDMT@1224|Proteobacteria 1224|Proteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C k141_14191_2 742767.HMPREF9456_00091 1.58e-63 203.0 COG0791@1|root,COG0791@2|Bacteria,4NM7I@976|Bacteroidetes,2FXHU@200643|Bacteroidia 976|Bacteroidetes M Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - - - - - - - - - - Peptidase_C92 k141_8611_1 1288826.MSNKSG1_08558 9.21e-164 461.0 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,465CV@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein C gspC GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - PDZ_2,T2SSC k141_8611_2 1288826.MSNKSG1_08553 0.0 960.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,4658F@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG1450 Type II secretory pathway, component PulD gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - SPOR,Secretin,Secretin_N k141_3043_1 1288826.MSNKSG1_01298 6.14e-219 627.0 COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k141_3043_2 1288826.MSNKSG1_01293 0.0 941.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_3043_3 1288826.MSNKSG1_01288 2.16e-91 268.0 COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,468GR@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3086 Positive regulator of sigma E activity rseC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC k141_3043_4 1288826.MSNKSG1_01283 3.28e-233 643.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,467RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3026 Negative regulator of sigma E activity rseB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_3043_5 1288826.MSNKSG1_01278 6.54e-97 285.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SCYE@1236|Gammaproteobacteria,468P4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3073 Negative regulator of sigma E activity mucA - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_C,RseA_N k141_3043_6 1288826.MSNKSG1_01273 5.37e-61 192.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_4458_1 550540.Fbal_1989 9.81e-05 42.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cold shock cspD GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_4458_2 765911.Thivi_4572 1.06e-148 428.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1WVYY@135613|Chromatiales 135613|Chromatiales C TIGRFAM isocitrate dehydrogenase, NADP-dependent - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - CBS,Iso_dh k141_21860_1 207954.MED92_16885 5.03e-136 406.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHWH@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis protein histidine kinase and related - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_11421_1 1485544.JQKP01000005_gene322 4.4e-19 85.5 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44W6H@713636|Nitrosomonadales 28216|Betaproteobacteria C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11 k141_11421_2 1123393.KB891316_gene1842 3.82e-34 125.0 2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria,1KRYR@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_11421_3 400682.PAC_15704303 1.55e-168 492.0 COG0069@1|root,KOG0399@2759|Eukaryota,38E4E@33154|Opisthokonta,3BECM@33208|Metazoa 33208|Metazoa E glutamate synthase (NADH) activity. It is involved in the biological process described with oxidation-reduction process - - - - - - - - - - - - Fer4_20,GATase_2,Glu_syn_central,Glu_synthase,Pyr_redox_2 k141_5283_1 396588.Tgr7_1968 3.32e-103 308.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1WWRA@135613|Chromatiales 135613|Chromatiales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_17843_1 398580.Dshi_0134 1.03e-08 52.8 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria 28211|Alphaproteobacteria H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_17843_2 1449351.RISW2_06105 7.76e-52 169.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,4KMNX@93682|Roseivivax 28211|Alphaproteobacteria O Redoxin pmpA - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - Redoxin k141_18507_1 587753.EY04_00520 1.9e-72 234.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RZ1Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - DUF4976,Sulfatase k141_11549_2 1288826.MSNKSG1_17748 0.0 932.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,4648C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_417_1 713586.KB900536_gene1841 1.01e-190 574.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_17103_1 1288826.MSNKSG1_06988 7.93e-120 371.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_21340_1 754477.Q7C_1175 4.21e-110 340.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales 72273|Thiotrichales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_3223_1 936455.KI421499_gene6980 3.77e-34 120.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2U9JC@28211|Alphaproteobacteria,3JZE0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sulphur oxidation protein SoxZ MA20_22825 - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ k141_3223_2 1049564.TevJSym_aw00360 3.45e-66 205.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfur oxidation protein SoxY soxY - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_3223_3 555778.Hneap_2070 5.42e-141 414.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_19895_2 1123368.AUIS01000003_gene1810 1.68e-25 103.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria 1236|Gammaproteobacteria T CBS-domain-containing membrane protein - - - ko:K07168 - - - - ko00000 - - - HPP k141_8743_1 1226994.AMZB01000136_gene5280 9.75e-40 139.0 COG2094@1|root,COG2094@2|Bacteria,1R95J@1224|Proteobacteria,1T0WF@1236|Gammaproteobacteria,1YE59@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Belongs to the DNA glycosylase MPG family - - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco k141_8743_2 1540257.JQMW01000011_gene1467 1.3e-20 87.4 COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,36IWM@31979|Clostridiaceae 186801|Clostridia S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep,Hexapep_2 k141_12281_2 641524.ADICYQ_4794 3.85e-31 121.0 COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,47JTC@768503|Cytophagia 976|Bacteroidetes CO Cytochrome c biogenesis protein transmembrane region dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_2476_1 396588.Tgr7_1912 3.13e-98 297.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_20638_1 1382303.JPOM01000001_gene2288 4.4e-47 171.0 COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2KFW9@204458|Caulobacterales 204458|Caulobacterales E peptidase S9B dipeptidylpeptidase IV domain protein - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 k141_4601_1 1288494.EBAPG3_440 7.63e-84 258.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,372D3@32003|Nitrosomonadales 28216|Betaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family cbbR - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_16395_1 216591.BCAS0686 4.83e-29 109.0 2E8RA@1|root,33329@2|Bacteria,1R39C@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_10881_1 1288826.MSNKSG1_04826 5.28e-189 537.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_10881_2 1288826.MSNKSG1_04821 2.35e-66 203.0 COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria,465I3@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C k141_11550_1 521000.PROVRETT_08536 1.23e-16 72.0 2DRJP@1|root,33C2Q@2|Bacteria,1NGIR@1224|Proteobacteria,1SUF3@1236|Gammaproteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_12282_1 314271.RB2654_10279 9.25e-111 330.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria 28211|Alphaproteobacteria H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 k141_5284_1 765911.Thivi_0418 3.93e-46 169.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXU3@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_5284_2 765913.ThidrDRAFT_3570 1.49e-33 120.0 COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria,1TJ8R@1236|Gammaproteobacteria,1WY66@135613|Chromatiales 135613|Chromatiales ET ABC-type amino acid transport signal transduction systems periplasmic component domain - - - - - - - - - - - - - k141_12982_1 321327.CYA_0261 1.5e-14 73.2 COG2988@1|root,COG2988@2|Bacteria,1GC3T@1117|Cyanobacteria,1GZBM@1129|Synechococcus 1117|Cyanobacteria E Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA k141_12982_2 631362.Thi970DRAFT_04497 2.01e-25 106.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_21341_1 349521.HCH_05401 1.42e-29 124.0 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,1XIKZ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_13652_1 1158762.KB898043_gene1044 8.24e-31 118.0 COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_13652_2 522373.Smlt1002 1.63e-43 146.0 COG0859@1|root,COG0859@2|Bacteria,1MZGQ@1224|Proteobacteria,1S7TT@1236|Gammaproteobacteria,1X6DP@135614|Xanthomonadales 135614|Xanthomonadales M PFAM glycosyl transferase family 9 - - - - - - - - - - - - - k141_13652_3 1537917.JU82_05695 4.24e-59 196.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2YREW@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k141_5952_1 1353537.TP2_13625 5.25e-97 293.0 COG1171@1|root,COG1171@2|Bacteria,1QTY3@1224|Proteobacteria,2VEUV@28211|Alphaproteobacteria,2XNVS@285107|Thioclava 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.3.1.15 ko:K01751 - - - - ko00000,ko01000 - - - PALP k141_17845_1 83406.HDN1F_10510 6.62e-27 110.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1J51M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG1109 Phosphomannomutase manB GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_15025_1 1288826.MSNKSG1_05361 7.04e-72 222.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RQVA@1236|Gammaproteobacteria,467B7@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_15025_2 1288826.MSNKSG1_05366 2.32e-49 167.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents permease component mlaE_1 - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS_2 k141_1121_1 1278309.KB907100_gene1806 6.29e-79 248.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XJH7@135619|Oceanospirillales 135619|Oceanospirillales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_1121_2 1278309.KB907100_gene1807 3.49e-216 598.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XI2H@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_1121_3 1278309.KB907100_gene1808 6.46e-101 322.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XI0M@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_14298_1 1173026.Glo7428_1784 9.78e-90 286.0 COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria 1117|Cyanobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_12983_1 1500890.JQNL01000001_gene1138 4.92e-34 128.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1X3U0@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar motor protein motB2 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_7363_1 1446473.JHWH01000017_gene3930 5.49e-239 660.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2PVIA@265|Paracoccus 28211|Alphaproteobacteria J GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_20639_1 639283.Snov_0963 1.19e-27 110.0 COG1024@1|root,COG1024@2|Bacteria,1PGH1@1224|Proteobacteria,2V7VS@28211|Alphaproteobacteria,3F22G@335928|Xanthobacteraceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - - ko:K13816 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - ECH_1 k141_17105_1 1249627.D779_1731 1.75e-92 289.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_17105_2 90813.JQMT01000001_gene701 1.16e-22 95.1 2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,1S67B@1236|Gammaproteobacteria,462DF@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_4603_1 1278309.KB907101_gene530 6.46e-87 273.0 COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria,1T1HY@1236|Gammaproteobacteria,1XRY3@135619|Oceanospirillales 135619|Oceanospirillales S Oxygen tolerance - - - - - - - - - - - - BatD k141_16396_1 1123517.JOMR01000001_gene43 2.05e-87 265.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,4611B@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system - - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_9405_1 1232437.KL661988_gene5 3.49e-76 237.0 COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,42SUK@68525|delta/epsilon subdivisions,2WPW0@28221|Deltaproteobacteria,2MM53@213118|Desulfobacterales 28221|Deltaproteobacteria M Cytidylyltransferase - - - - - - - - - - - - CTP_transf_3 k141_7382_2 713586.KB900536_gene1806 1.07e-177 510.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_9421_1 1278309.KB907108_gene1589 1.87e-56 185.0 COG4447@1|root,COG4447@2|Bacteria,1R5ZV@1224|Proteobacteria,1S0FG@1236|Gammaproteobacteria,1XMK0@135619|Oceanospirillales 135619|Oceanospirillales S Photosynthesis system II assembly factor YCF48 - - - - - - - - - - - - PSII_BNR k141_9421_2 1278309.KB907108_gene1588 2.09e-145 432.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XITB@135619|Oceanospirillales 135619|Oceanospirillales S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_15042_1 647113.Metok_1325 6.73e-67 218.0 COG0477@1|root,arCOG00130@2157|Archaea,2XU3E@28890|Euryarchaeota,23QKI@183939|Methanococci 183939|Methanococci G PFAM Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_11569_1 1288826.MSNKSG1_15112 4.26e-174 505.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,464R6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_15784_1 1124780.ANNU01000015_gene2000 4.36e-56 184.0 COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia 976|Bacteroidetes J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_3243_1 1278309.KB907106_gene1291 1.13e-194 548.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1XHSG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the peptidase M24B family pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_3243_2 1278309.KB907106_gene1290 1.84e-114 332.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1XK9X@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 k141_3243_4 247634.GPB2148_2778 3.88e-18 79.7 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1J6Z2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_8156_1 566466.NOR53_3282 2.3e-54 191.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1J4YE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_19288_1 1288826.MSNKSG1_06138 1.2e-120 353.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RSCK@1236|Gammaproteobacteria,463XY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Saccharopine dehydrogenase lys - - - - - - - - - - - Sacchrp_dh_NADP k141_19288_2 1288826.MSNKSG1_06143 8.17e-92 268.0 2DM91@1|root,327BS@2|Bacteria,1R3C3@1224|Proteobacteria,1S6CW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10906_1 391615.ABSJ01000059_gene2151 9.95e-165 494.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1J4DT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_17870_1 522306.CAP2UW1_1761 9.54e-71 220.0 COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,2WG8I@28216|Betaproteobacteria 28216|Betaproteobacteria S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 k141_17870_2 1209072.ALBT01000038_gene2453 2.1e-64 207.0 COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,1RYN3@1236|Gammaproteobacteria,1FHSC@10|Cellvibrio 1236|Gammaproteobacteria K HTH domain - - - - - - - - - - - - HTH_11,WYL k141_16416_1 1046714.AMRX01000008_gene1142 9.32e-38 131.0 COG0517@1|root,COG0517@2|Bacteria,1N13S@1224|Proteobacteria,1SA4N@1236|Gammaproteobacteria,467VA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain in cystathionine beta-synthase and other proteins. acuB - - ko:K04767 - - - - ko00000 - - - CBS k141_16416_2 697284.ERIC2_c39150 1.66e-174 508.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,2773A@186822|Paenibacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_12302_1 111781.Lepto7376_0945 3.56e-09 58.5 COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1G0VA@1117|Cyanobacteria,1H9ND@1150|Oscillatoriales 1117|Cyanobacteria T PFAM Adenylate and Guanylate cyclase catalytic domain cya1 - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - FHA,Guanylate_cyc k141_1823_1 1335757.SPICUR_01535 1.28e-24 97.4 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales 135613|Chromatiales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_18513_1 1049564.TevJSym_aw00300 1.43e-88 273.0 2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11570_1 1247024.JRLH01000001_gene964 7.93e-59 193.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca GO:0001680,GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016437,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042245,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k141_437_1 1278309.KB907099_gene2801 2.59e-154 461.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_19904_1 1288826.MSNKSG1_14927 3.31e-99 309.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1SJP8@1236|Gammaproteobacteria,46D4Y@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,EAL,GGDEF,PAS,PAS_9,Response_reg,dCache_1,dCache_3 k141_19904_2 1288826.MSNKSG1_14922 5.54e-209 577.0 28JGK@1|root,2Z9AA@2|Bacteria,1MWFY@1224|Proteobacteria,1RPK6@1236|Gammaproteobacteria,46635@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3034) - - - - - - - - - - - - DUF3034 k141_19904_3 1288826.MSNKSG1_14917 2.95e-99 288.0 COG2346@1|root,COG2346@2|Bacteria,1N005@1224|Proteobacteria,1S8XK@1236|Gammaproteobacteria,468NR@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2346 Truncated hemoglobins glbN - - ko:K06886 - - - - ko00000 - - - Bac_globin k141_19904_4 1288826.MSNKSG1_14912 2.5e-80 239.0 COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,1SANJ@1236|Gammaproteobacteria,46BS8@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_19904_5 1288826.MSNKSG1_14907 0.0 916.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,464KE@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_3244_1 1123401.JHYQ01000012_gene2891 2.05e-77 251.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales 72273|Thiotrichales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_7383_1 880073.Calab_2354 4.26e-43 164.0 COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K07675 ko02020,map02020 M00473 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_8157_1 744980.TRICHSKD4_2052 4.23e-55 181.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TRTG@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the arginase family rocF - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_8157_2 911045.PSE_2943 4.68e-55 182.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSBQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ornithine cyclodeaminase arcB - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_18035_1 1288826.MSNKSG1_01963 2.55e-90 274.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RNHA@1236|Gammaproteobacteria,46CTQ@72275|Alteromonadaceae 1236|Gammaproteobacteria V HlyD membrane-fusion protein of T1SS emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_18035_2 1288826.MSNKSG1_01958 6.56e-234 646.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,46CK6@72275|Alteromonadaceae 1236|Gammaproteobacteria U ABC-2 family transporter protein ybhR GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_18035_3 1288826.MSNKSG1_01953 5.12e-245 675.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,46A8T@72275|Alteromonadaceae 1236|Gammaproteobacteria U ABC-2 family transporter protein ybhS GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 k141_15153_8 1288826.MSNKSG1_12592 2.59e-227 626.0 COG2267@1|root,COG2267@2|Bacteria,1R4YR@1224|Proteobacteria,1S1JB@1236|Gammaproteobacteria,468TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_15153_9 1288826.MSNKSG1_12597 1.54e-175 490.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae 1236|Gammaproteobacteria P molybdenum ABC transporter, periplasmic modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_15153_10 1288826.MSNKSG1_12602 5.23e-157 441.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,465C4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4149 ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_15153_11 1288826.MSNKSG1_12607 9.69e-251 689.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,464HI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_15153_12 1288826.MSNKSG1_12612 5.96e-208 575.0 COG0596@1|root,COG0596@2|Bacteria,1R4PH@1224|Proteobacteria,1S03W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,adh_short k141_15153_13 1288826.MSNKSG1_12617 8.19e-244 671.0 COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,1S088@1236|Gammaproteobacteria 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1 k141_15153_14 351348.Maqu_3550 1.4e-152 429.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,465GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases crp GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,cNMP_binding k141_15153_15 1288826.MSNKSG1_12627 5.91e-96 279.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,4672B@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation yhfA - - ko:K07397 - - - - ko00000 - - - OsmC k141_15153_16 1288826.MSNKSG1_12632 5.48e-191 530.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,465SJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3412,iSDY_1059.SDY_0027 AdoMet_dc k141_15153_17 1288826.MSNKSG1_12637 2.25e-136 386.0 COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,466Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 k141_15153_18 1288826.MSNKSG1_12642 1.55e-190 530.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,465B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the pirin family XCC2717 - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_15153_19 1288826.MSNKSG1_12647 3.74e-206 570.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,464XM@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphoribulokinase prkB GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_15153_20 1288826.MSNKSG1_12652 1.37e-200 590.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - DUF1631,EAL,GGDEF,PilZ k141_15945_1 765869.BDW_03945 3.27e-18 83.6 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MTPM@213481|Bdellovibrionales,2WJVV@28221|Deltaproteobacteria 213481|Bdellovibrionales V Hydrophobe amphiphile Efflux-1 (HAE1) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_15945_2 349124.Hhal_1990 7.01e-09 63.5 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales 135613|Chromatiales MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_13163_1 391615.ABSJ01000045_gene2001 5.28e-117 340.0 2DBGM@1|root,2Z958@2|Bacteria,1R715@1224|Proteobacteria,1SR3R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIR domain - - - - - - - - - - - - TIR_2 k141_11064_1 1265313.HRUBRA_00801 2.93e-138 404.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_1311_1 1198232.CYCME_0502 5.03e-22 94.0 COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR k141_18062_1 265072.Mfla_0632 2.82e-94 288.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KMD1@206350|Nitrosomonadales 206350|Nitrosomonadales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_10338_1 501479.ACNW01000062_gene2740 3.3e-73 239.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_2644_1 396588.Tgr7_2234 2e-157 449.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_8877_1 1278309.KB907100_gene2006 5.04e-149 429.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XI7F@135619|Oceanospirillales 135619|Oceanospirillales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_8877_2 1278309.KB907100_gene2007 3e-47 153.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1XKF8@135619|Oceanospirillales 135619|Oceanospirillales S 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase - - - - - - - - - - - - DUF971 k141_8300_1 314278.NB231_16053 3.18e-126 384.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales 135613|Chromatiales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_4791_1 697282.Mettu_0112 1.4e-83 254.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XEBI@135618|Methylococcales 135618|Methylococcales S Belongs to the BI1 family - - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_16587_1 317013.NY99_15385 4.1e-93 294.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X4BT@135614|Xanthomonadales 135614|Xanthomonadales I 3-hydroxyacyl-coa dehydrogenase fadB - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_6127_1 1385515.N791_02270 6.77e-69 221.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1X2X5@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_12492_1 234267.Acid_0447 5.09e-63 204.0 COG2159@1|root,COG2159@2|Bacteria,3Y7DZ@57723|Acidobacteria 57723|Acidobacteria S PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_14443_1 983545.Glaag_0147 8.95e-13 69.7 COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,4672W@72275|Alteromonadaceae 1236|Gammaproteobacteria U general secretion pathway protein gspH GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl k141_14443_2 765914.ThisiDRAFT_1920 2.53e-57 182.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales 135613|Chromatiales U general secretion pathway protein G - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_14443_3 1318628.MARLIPOL_06799 8.37e-38 140.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,465B4@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein F gspF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_21515_1 1121013.P873_09320 9.09e-09 57.8 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1X2X5@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_21515_2 1298593.TOL_1531 2.45e-139 403.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XHYW@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_13850_1 1278309.KB907099_gene2825 7.5e-86 255.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1XK41@135619|Oceanospirillales 135619|Oceanospirillales O Peroxiredoxin - - - - - - - - - - - - Redoxin k141_9571_1 1178482.BJB45_11140 2.14e-48 166.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,1XHUN@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_9571_2 314264.ROS217_09195 7.47e-23 95.1 COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria,46NR2@74030|Roseovarius 28211|Alphaproteobacteria K COG1802 Transcriptional regulators - - - ko:K11475 - - - - ko00000,ko03000 - - - FCD,GntR k141_7542_1 589873.EP13_10740 6.83e-58 191.0 COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,4647V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - 2.4.1.266 ko:K13693 - - - - ko00000,ko01000,ko01003 - GT81 - - k141_7542_2 156578.ATW7_03017 3.56e-53 189.0 COG3769@1|root,COG4240@1|root,COG3769@2|Bacteria,COG4240@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mannosyl-3-phosphoglycerate phosphatase yedP - 2.7.1.31,3.1.3.70 ko:K07026,ko:K15918 ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514,R05790 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3,S6PP k141_7542_3 1278309.KB907102_gene250 9.99e-248 682.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XHTE@135619|Oceanospirillales 135619|Oceanospirillales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 k141_7542_4 1278309.KB907102_gene249 3.64e-249 685.0 COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,1RMY4@1236|Gammaproteobacteria,1XII8@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter substrate-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_7542_5 1278309.KB907102_gene248 2.33e-256 708.0 COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,1RQ4G@1236|Gammaproteobacteria,1XIK8@135619|Oceanospirillales 135619|Oceanospirillales E Binding-protein-dependent transport system inner membrane component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_7542_6 1278309.KB907102_gene247 4.18e-180 504.0 COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,1RP1E@1236|Gammaproteobacteria,1XJ43@135619|Oceanospirillales 135619|Oceanospirillales E Binding-protein-dependent transport system inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_7542_7 1137799.GZ78_24090 4.23e-117 340.0 COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,1XIB3@135619|Oceanospirillales 135619|Oceanospirillales S ThiJ PfpI - - - - - - - - - - - - DJ-1_PfpI k141_7542_8 1137799.GZ78_24080 7.21e-74 230.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1XHQ1@135619|Oceanospirillales 135619|Oceanospirillales S NAD(P)-dependent - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_13164_1 1123514.KB905899_gene1275 1e-94 285.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,463X7@72273|Thiotrichales 72273|Thiotrichales G 6-phosphogluconate dehydrogenase, C-terminal domain - - - - - - - - - - - - 6PGD,NAD_binding_2 k141_10339_1 1278309.KB907111_gene3396 6.34e-128 378.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1XHX6@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_2645_1 472759.Nhal_3010 2.3e-97 297.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales 135613|Chromatiales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_1312_1 1449351.RISW2_13825 1.05e-52 181.0 COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2U0EV@28211|Alphaproteobacteria,4KNMK@93682|Roseivivax 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF898) - - - - - - - - - - - - DUF898 k141_16588_1 589865.DaAHT2_1626 1.48e-33 132.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1R4NG@1224|Proteobacteria 1224|Proteobacteria T periplasmic ligand-binding sensor domain - - - - - - - - - - - - CHASE,GGDEF,PAS_4 k141_18712_1 1234364.AMSF01000025_gene3595 5.69e-101 308.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1X3NQ@135614|Xanthomonadales 135614|Xanthomonadales O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_3389_2 1288826.MSNKSG1_14147 0.0 1235.0 COG0380@1|root,COG0561@1|root,COG0380@2|Bacteria,COG0561@2|Bacteria,1MUIY@1224|Proteobacteria,1RNG7@1236|Gammaproteobacteria,469G3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyltransferase family 20 ggpS - 2.4.1.213 ko:K03692 - - - - ko00000,ko01000 - GT20 - Glyco_transf_20,S6PP k141_12493_2 946362.XP_004989785.1 1.74e-05 49.3 COG1233@1|root,KOG4254@2759|Eukaryota,38GIP@33154|Opisthokonta 33154|Opisthokonta H all-trans-retinol 13,14-reductase activity RETSAT GO:0001523,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005640,GO:0005737,GO:0005783,GO:0005789,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0009987,GO:0010817,GO:0012505,GO:0016020,GO:0016101,GO:0016491,GO:0016627,GO:0019867,GO:0031090,GO:0031965,GO:0031967,GO:0031968,GO:0031975,GO:0031984,GO:0034308,GO:0034754,GO:0042175,GO:0042445,GO:0042572,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0051786,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0098588,GO:0098805,GO:0098827,GO:1901615 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 k141_18064_1 1279017.AQYJ01000026_gene58 1.3e-99 325.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_1964_1 2340.JV46_02990 3.17e-34 133.0 COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth k141_1964_2 697282.Mettu_3066 3.14e-99 296.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria,1XEYK@135618|Methylococcales 135618|Methylococcales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_2646_1 1392489.JPOL01000002_gene1443 3.34e-40 148.0 COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia,2XJ4E@283735|Leeuwenhoekiella 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_14444_1 95619.PM1_0200775 2.18e-73 243.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_14444_2 1304888.ATWF01000001_gene987 5.03e-12 67.8 COG1807@1|root,COG1807@2|Bacteria,2GGAM@200930|Deferribacteres 200930|Deferribacteres M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_6128_1 1288826.MSNKSG1_01163 9.56e-243 684.0 COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria,465VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_19410_1 309807.SRU_0770 3.15e-92 285.0 COG2850@1|root,COG2850@2|Bacteria,4PEBP@976|Bacteroidetes,1FIRX@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S A domain family that is part of the cupin metalloenzyme superfamily. - - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_16589_1 1192034.CAP_6452 1.37e-65 201.0 COG1196@1|root,COG1196@2|Bacteria,1RJS1@1224|Proteobacteria,43236@68525|delta/epsilon subdivisions,2WWXG@28221|Deltaproteobacteria,2YV0I@29|Myxococcales 28221|Deltaproteobacteria D Domain of unknown function (DUF4150) - - - - - - - - - - - - DUF4150 k141_16589_2 1134474.O59_004303 2.13e-20 91.3 COG1413@1|root,COG1413@2|Bacteria,1NUN2@1224|Proteobacteria,1RYE5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C lyase activity - - - - - - - - - - - - HEAT_2 k141_3390_1 1415754.JQMK01000006_gene3717 1.22e-34 125.0 COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria,1T1HV@1236|Gammaproteobacteria,46D48@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ybbO GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - - - - - - - - - - adh_short k141_3390_2 443152.MDG893_07760 3.15e-53 185.0 COG1061@1|root,COG2227@1|root,COG2932@1|root,COG3886@1|root,COG1061@2|Bacteria,COG2227@2|Bacteria,COG2932@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4657B@72275|Alteromonadaceae 1236|Gammaproteobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,Methyltransf_25,PLDc_2,ResIII k141_9573_1 1453501.JELR01000002_gene677 1.23e-101 300.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,464KC@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_1314_1 391595.RLO149_c015650 4.94e-99 308.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria,2P2PR@2433|Roseobacter 28211|Alphaproteobacteria F Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_15948_1 1123401.JHYQ01000002_gene2785 4.99e-74 234.0 COG0547@1|root,COG0547@2|Bacteria,1PI4H@1224|Proteobacteria,1T9UI@1236|Gammaproteobacteria,4623U@72273|Thiotrichales 72273|Thiotrichales E PFAM Glycosyl transferase family, a b domain - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_580_2 1278309.KB907106_gene1222 1.12e-159 464.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XH4V@135619|Oceanospirillales 135619|Oceanospirillales KLT Serine Threonine protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_13165_2 999141.GME_09811 2.47e-19 80.5 COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1XMMM@135619|Oceanospirillales 135619|Oceanospirillales H COG2104 Sulfur transfer protein involved in thiamine biosynthesis - - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_12494_1 265072.Mfla_0568 9.84e-227 649.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,2KMGG@206350|Nitrosomonadales 206350|Nitrosomonadales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_15949_1 887898.HMPREF0551_0941 8.1e-59 192.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1K293@119060|Burkholderiaceae 28216|Betaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_11710_1 765913.ThidrDRAFT_0469 2.27e-117 367.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1X08T@135613|Chromatiales 135613|Chromatiales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_11710_2 1278309.KB907104_gene967 1.5e-113 334.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XH8W@135619|Oceanospirillales 135619|Oceanospirillales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_14445_1 1500894.JQNN01000001_gene1615 2e-16 76.6 COG0681@1|root,COG0681@2|Bacteria,1R7Z4@1224|Proteobacteria,2VPZJ@28216|Betaproteobacteria,474PT@75682|Oxalobacteraceae 28216|Betaproteobacteria U Signal peptidase, peptidase S26 - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_14445_2 1249627.D779_1814 2.06e-16 79.7 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,1S73A@1236|Gammaproteobacteria,1WYN0@135613|Chromatiales 135613|Chromatiales M PFAM Cell wall hydrolase - - - - - - - - - - - - Hydrolase_2 k141_18713_2 870187.Thini_3064 3.94e-31 110.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,461IH@72273|Thiotrichales 72273|Thiotrichales K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_8301_1 207954.MED92_15028 1.13e-104 316.0 COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,1T1XV@1236|Gammaproteobacteria,1XJ40@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,sCache_2 k141_1328_1 2340.JV46_08870 3.2e-95 308.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1J7JF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C k141_12510_1 1278309.KB907110_gene3207 9.72e-39 143.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XI1F@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_12510_2 1278309.KB907110_gene3206 5.06e-159 449.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XI3P@135619|Oceanospirillales 135619|Oceanospirillales S pyrophosphohydrolase mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_12510_3 1278309.KB907110_gene3205 9.25e-56 177.0 2EANG@1|root,334QZ@2|Bacteria,1NCA4@1224|Proteobacteria,1SG8W@1236|Gammaproteobacteria,1XM13@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_12510_4 1278309.KB907110_gene3204 6.19e-173 506.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1XIF3@135619|Oceanospirillales 135619|Oceanospirillales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_11085_1 1123501.KB902288_gene1675 1.53e-111 330.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_14465_1 1121904.ARBP01000016_gene5186 4.37e-111 334.0 COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_3412_1 1163617.SCD_n02227 5.61e-76 240.0 COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,2WGKB@28216|Betaproteobacteria 28216|Betaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_2134_2 314345.SPV1_12225 1.36e-21 92.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif - - 3.6.4.12,3.6.4.13 ko:K03655,ko:K05592 ko03018,ko03440,map03018,map03440 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03400 - - - DbpA,RRM_1 k141_2134_3 519989.ECTPHS_06212 6.41e-43 156.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1WWEX@135613|Chromatiales 135613|Chromatiales S PFAM ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_2834_1 28072.Nos7524_2859 1.62e-28 126.0 COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1HIHD@1161|Nostocales 1117|Cyanobacteria Q Hemolysin-type calcium-binding repeat (2 copies) - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF4347,HemolysinCabind k141_9806_1 1123296.JQKE01000045_gene719 3.65e-84 254.0 COG0515@1|root,COG0515@2|Bacteria,1QZ10@1224|Proteobacteria 1224|Proteobacteria KLT Domain of unknown function (DUF4328) - - - - - - - - - - - - DUF4328 k141_17456_1 439235.Dalk_4029 3.21e-135 398.0 COG0019@1|root,COG0019@2|Bacteria,1R4VG@1224|Proteobacteria,42Z5C@68525|delta/epsilon subdivisions,2WUBY@28221|Deltaproteobacteria,2MMY8@213118|Desulfobacterales 28221|Deltaproteobacteria E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_18880_1 754476.Q7A_2371 3.82e-91 289.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,460A5@72273|Thiotrichales 72273|Thiotrichales N The M ring may be actively involved in energy transduction - - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_19568_1 1122135.KB893135_gene843 2.09e-81 255.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2U2FB@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Oxidoreductase - - - - - - - - - - - - DAO k141_1446_1 1288826.MSNKSG1_13762 0.0 1072.0 COG0491@1|root,COG0494@1|root,COG0491@2|Bacteria,COG0494@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,46AP6@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes blaB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,NUDIX k141_1446_2 1288826.MSNKSG1_13767 2.34e-301 822.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,466XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_1446_3 1288826.MSNKSG1_13772 3.64e-113 325.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,466WN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_1446_4 1288826.MSNKSG1_13777 0.0 1035.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464YW@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C2 k141_20999_1 694427.Palpr_0973 2.82e-38 139.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,2FMZ9@200643|Bacteroidia,22WMK@171551|Porphyromonadaceae 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_11902_2 1122201.AUAZ01000025_gene3560 4.57e-276 760.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,4655F@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3344 Retron-type reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k141_9117_1 1278309.KB907103_gene1020 1.35e-226 630.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,1XIHF@135619|Oceanospirillales 135619|Oceanospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_9117_3 1278309.KB907103_gene1018 9.49e-10 56.6 2CAI4@1|root,33JPF@2|Bacteria,1NP1T@1224|Proteobacteria,1SY6Z@1236|Gammaproteobacteria,1XQGG@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15403_1 1001585.MDS_0329 5.11e-46 171.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1YDXT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Adenylate cyclase NT domain cyaA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2672,iECOK1_1307.ECOK1_4253,iECS88_1305.ECS88_4229,iUMN146_1321.UM146_19155,iUTI89_1310.UTI89_C4365 Adenyl_cycl_N,Adenylate_cycl k141_20277_1 1499967.BAYZ01000044_gene2997 1.08e-76 235.0 COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria 2|Bacteria K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_13993_2 1122599.AUGR01000014_gene568 2.14e-76 227.0 2BBG1@1|root,324ZB@2|Bacteria,1MYV0@1224|Proteobacteria,1S7JR@1236|Gammaproteobacteria,1XKEC@135619|Oceanospirillales 135619|Oceanospirillales S Quinohemoprotein amine dehydrogenase, gamma subunit - - - - - - - - - - - - QH-AmDH_gamma k141_13993_3 1278309.KB907099_gene2646 1.36e-198 558.0 COG3391@1|root,COG3391@2|Bacteria,1P6I0@1224|Proteobacteria,1RS81@1236|Gammaproteobacteria,1XJ3Q@135619|Oceanospirillales 135619|Oceanospirillales S Quinohemoprotein amine dehydrogenase - - - - - - - - - - - - - k141_13993_4 1278309.KB907099_gene2647 0.0 928.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1S0VQ@1236|Gammaproteobacteria,1XI1P@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_4215_1 1288826.MSNKSG1_04831 2.43e-180 505.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,4645A@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1840 ABC-type Fe3 transport system, periplasmic component fbpA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_4215_2 1288826.MSNKSG1_04826 1.21e-196 557.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,465RX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1178 ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_11235_1 1042375.AFPL01000025_gene1229 6.8e-135 404.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,46478@72275|Alteromonadaceae 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_15404_1 317025.Tcr_1675 2.03e-27 112.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,460U9@72273|Thiotrichales 72273|Thiotrichales M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 k141_1447_1 391596.PBAL39_10840 3.76e-54 196.0 COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1IQ66@117747|Sphingobacteriia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_20278_1 1278309.KB907099_gene2378 4.63e-93 285.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XI2S@135619|Oceanospirillales 135619|Oceanospirillales J Involved in the processing of the 5'end of 16S rRNA - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_6315_1 1183438.GKIL_1932 2.64e-22 100.0 COG0719@1|root,COG0719@2|Bacteria,1G0K0@1117|Cyanobacteria 1117|Cyanobacteria O ABC-type transport system involved in Fe-S cluster assembly, permease component sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 k141_763_1 1297569.MESS2_1370004 2.79e-07 51.6 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_763_2 1122137.AQXF01000001_gene2870 5.39e-99 294.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria 28211|Alphaproteobacteria E prephenate dehydrogenase tyrC GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH k141_57_2 159087.Daro_0918 3.94e-09 65.1 COG0457@1|root,COG4319@1|root,COG0457@2|Bacteria,COG4319@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,2KUGG@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440,TPR_11,TPR_16,TPR_17 k141_18889_1 1278309.KB907100_gene2212 2.42e-145 424.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XIYC@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_7040_1 357804.Ping_2544 2.79e-68 213.0 COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria 1224|Proteobacteria Q PFAM Methyltransferase type - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_7040_2 349521.HCH_04452 1.22e-49 171.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XING@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_2151_1 1122137.AQXF01000002_gene610 1.97e-68 210.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB k141_2151_2 1122137.AQXF01000002_gene609 4.96e-16 75.9 COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria,1Q49P@1224|Proteobacteria,2UMKG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - FHA,cNMP_binding k141_13328_1 322710.Avin_05020 1.94e-35 134.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_2885 Glu_cys_ligase k141_14020_1 582744.Msip34_2264 1.12e-39 135.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,2KMXW@206350|Nitrosomonadales 206350|Nitrosomonadales S Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_14020_2 697282.Mettu_4334 1.58e-44 150.0 COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1XFDF@135618|Methylococcales 135618|Methylococcales O Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_18188_1 104623.Ser39006_02073 9.44e-72 221.0 COG1522@1|root,COG1522@2|Bacteria,1RA2G@1224|Proteobacteria,1RY3I@1236|Gammaproteobacteria,4040J@613|Serratia 1236|Gammaproteobacteria K helix_turn_helix ASNC type - - - ko:K15782 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24 k141_9817_1 460265.Mnod_0870 4.25e-33 131.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,1JTVR@119045|Methylobacteriaceae 28211|Alphaproteobacteria I PFAM Acyltransferase - - - - - - - - - - - - Acyl_transf_3 k141_15425_1 413404.Rmag_0035 8.34e-119 354.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1J4DV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - iJN746.PP_0104 COX1 k141_11261_1 1278309.KB907100_gene2276 0.0 972.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XH7W@135619|Oceanospirillales 135619|Oceanospirillales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_11261_2 1278309.KB907100_gene2277 6.71e-112 323.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1XJQG@135619|Oceanospirillales 135619|Oceanospirillales E D,D-heptose 1,7-bisphosphate phosphatase gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like k141_11261_3 1278309.KB907100_gene2278 4.39e-42 139.0 2DQRC@1|root,32ZAU@2|Bacteria,1N730@1224|Proteobacteria,1SCPP@1236|Gammaproteobacteria,1XQ33@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11261_4 305700.B447_05730 1.19e-136 393.0 28K85@1|root,2Z9W1@2|Bacteria,1MWB1@1224|Proteobacteria,2W4HH@28216|Betaproteobacteria 28216|Betaproteobacteria K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_11261_5 1232683.ADIMK_3156 3.97e-233 651.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464HE@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter agcS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_5674_1 765912.Thimo_2102 2.24e-87 264.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1WW0K@135613|Chromatiales 135613|Chromatiales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_5674_2 396588.Tgr7_1140 1.58e-48 163.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1WWKH@135613|Chromatiales 135613|Chromatiales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_6329_2 1123399.AQVE01000011_gene1230 1.75e-21 93.2 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Xanthine and CO dehydrogenases maturation factor XdhC CoxF family xdhC2 - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_9818_1 1278309.KB907102_gene267 2.8e-82 249.0 2AH9S@1|root,317JX@2|Bacteria,1RKKP@1224|Proteobacteria,1S7FI@1236|Gammaproteobacteria,1XKWT@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_18189_1 1046714.AMRX01000003_gene31 6.29e-69 222.0 28K2M@1|root,2Z9RY@2|Bacteria,1R6RC@1224|Proteobacteria,1RP9F@1236|Gammaproteobacteria,466KK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Beta_helix k141_13329_1 861299.J421_0135 2.69e-33 130.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups epsO - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k141_17468_1 1121921.KB898706_gene2571 9.41e-91 285.0 COG3746@1|root,COG3746@2|Bacteria,1Q3GY@1224|Proteobacteria,1RNGT@1236|Gammaproteobacteria 1236|Gammaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - k141_3556_1 349124.Hhal_0025 1.98e-163 471.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales 135613|Chromatiales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_16798_1 1278309.KB907101_gene437 4.56e-242 692.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XHGI@135619|Oceanospirillales 135619|Oceanospirillales P cation transport ATPase - - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_58_1 1317124.DW2_02779 4.11e-140 406.0 COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,2TUCZ@28211|Alphaproteobacteria,2XMR8@285107|Thioclava 28211|Alphaproteobacteria G Sugar ABC transporter substrate-binding protein MA20_37650 - - ko:K17315 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - SBP_bac_1,SBP_bac_8 k141_4237_2 1123228.AUIH01000007_gene2598 2.98e-65 212.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales 135619|Oceanospirillales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_14727_1 1041139.KB902690_gene667 3.35e-22 91.3 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2U3PI@28211|Alphaproteobacteria,4BNI9@82115|Rhizobiaceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_14727_2 1278309.KB907100_gene2320 5.96e-72 227.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XH97@135619|Oceanospirillales 135619|Oceanospirillales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_19585_1 1278309.KB907101_gene642 0.0 1195.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XI5I@135619|Oceanospirillales 135619|Oceanospirillales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_19585_2 1278309.KB907101_gene641 7.35e-103 305.0 2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria,1XMCG@135619|Oceanospirillales 135619|Oceanospirillales S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV k141_19585_3 1278309.KB907101_gene640 3.23e-81 241.0 2B2JB@1|root,31V4J@2|Bacteria,1N4EU@1224|Proteobacteria,1S6JW@1236|Gammaproteobacteria,1XMAH@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2750) - - - - - - - - - - - - DUF2750 k141_19585_4 745411.B3C1_01325 2.35e-41 147.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1J51T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_7755_2 857087.Metme_2595 1.21e-44 147.0 COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,1XFBE@135618|Methylococcales 135618|Methylococcales S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions ppnP - 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 - R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 - - - DUF1255 k141_2850_1 1198232.CYCME_2045 3.94e-07 51.6 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales 72273|Thiotrichales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_2850_2 768671.ThimaDRAFT_0894 6.22e-47 152.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1WYVV@135613|Chromatiales 135613|Chromatiales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_2850_3 240292.Ava_1515 4.79e-37 126.0 COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HNYF@1161|Nostocales 1117|Cyanobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_2850_4 713586.KB900538_gene7 1.3e-61 199.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1WX4T@135613|Chromatiales 135613|Chromatiales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_1461_1 1232683.ADIMK_2026 1.37e-70 218.0 2911Z@1|root,2ZNPI@2|Bacteria,1RCI2@1224|Proteobacteria,1S3N5@1236|Gammaproteobacteria,46AKF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1461_3 1278309.KB907099_gene2942 2.08e-267 737.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHCN@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_1461_4 1278309.KB907099_gene2941 2.69e-108 313.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S3PH@1236|Gammaproteobacteria,1XK4P@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_1461_5 1278309.KB907099_gene2940 1.35e-143 411.0 COG4663@1|root,COG4663@2|Bacteria,1MUA1@1224|Proteobacteria,1RZAE@1236|Gammaproteobacteria,1XIUG@135619|Oceanospirillales 135619|Oceanospirillales Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_14021_1 1278309.KB907100_gene1809 3.48e-44 148.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XJ63@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_14021_2 1278309.KB907100_gene1808 2.44e-154 466.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XI0M@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_5675_1 1288826.MSNKSG1_10203 6.55e-73 223.0 COG0179@1|root,COG0179@2|Bacteria,1R51B@1224|Proteobacteria,1RQI9@1236|Gammaproteobacteria,469ZF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpaG1 - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_5675_2 1288826.MSNKSG1_10198 7.15e-94 279.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,1RMWJ@1236|Gammaproteobacteria,468SR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the HpcH HpaI aldolase family rhmA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016829,GO:0016830,GO:0016832,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0071704 4.1.2.52,4.1.2.53 ko:K02510,ko:K12660 ko00051,ko00350,ko01120,map00051,map00350,map01120 - R01645,R01647,R02261 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_2049 HpcH_HpaI k141_3557_1 313628.LNTAR_09004 1.96e-25 102.0 COG0231@1|root,COG0231@2|Bacteria 2|Bacteria J translation elongation factor activity efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_10530_1 1279017.AQYJ01000021_gene2802 4.48e-32 120.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_10530_2 870187.Thini_3697 1.85e-117 352.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,45ZYG@72273|Thiotrichales 72273|Thiotrichales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_10530_3 1255043.TVNIR_3397 2.37e-46 157.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales 135613|Chromatiales I PFAM CDP-alcohol phosphatidyltransferase - - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_10530_4 472759.Nhal_0874 8.19e-65 216.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2066) - - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_12073_1 754477.Q7C_1763 4.24e-141 412.0 COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,461NY@72273|Thiotrichales 72273|Thiotrichales U glutamate--cysteine ligase - - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GshA k141_12073_2 1209072.ALBT01000030_gene2287 1.12e-13 69.7 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1FG8W@10|Cellvibrio 1236|Gammaproteobacteria H Prokaryotic glutathione synthetase, N-terminal domain gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k141_19055_1 1005048.CFU_3911 0.000106 52.0 COG1388@1|root,COG4254@1|root,COG1388@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VR04@28216|Betaproteobacteria,4732V@75682|Oxalobacteraceae 28216|Betaproteobacteria M FecR protein - - - - - - - - - - - - FecR,LysM k141_1603_2 2340.JV46_16020 4.1e-201 563.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1J4IA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3734,iSBO_1134.SBO_4018 URO-D k141_1603_3 396588.Tgr7_3019 1.49e-266 738.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 k141_3005_1 396588.Tgr7_3044 2.12e-88 267.0 COG0515@1|root,COG0515@2|Bacteria,1NUIB@1224|Proteobacteria 1224|Proteobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase k141_17635_2 1278309.KB907102_gene72 2.42e-239 663.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XIF2@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_17635_3 1278309.KB907102_gene73 1.06e-204 568.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1XIMD@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_17635_4 1278309.KB907102_gene74 0.0 1600.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XIDI@135619|Oceanospirillales 135619|Oceanospirillales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_17635_5 1278309.KB907102_gene75 1.4e-170 486.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1XHHB@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_12774_1 1288826.MSNKSG1_11428 1.72e-54 192.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9 k141_7887_1 95619.PM1_0227545 5.17e-87 277.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_19714_1 1278309.KB907100_gene2137 1.31e-177 501.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XHNI@135619|Oceanospirillales 135619|Oceanospirillales E arginine N-succinyltransferase - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_19714_2 1278309.KB907100_gene2138 1.16e-279 773.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XHCT@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD - 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_19714_3 633149.Bresu_1342 2.8e-30 119.0 COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2U0HD@28211|Alphaproteobacteria,2KFUS@204458|Caulobacterales 204458|Caulobacterales E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) astB - 3.5.3.23 ko:K01484 ko00330,ko01100,map00330,map01100 - R04189 RC00024 ko00000,ko00001,ko01000 - - - AstB k141_183_1 246200.SPO0971 1.94e-141 416.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,4NA18@97050|Ruegeria 28211|Alphaproteobacteria C hmm pf05199 - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_3006_1 1158756.AQXQ01000009_gene998 8.75e-50 170.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_17636_1 626887.J057_14445 7.46e-31 125.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG4796 Type II secretory pathway, component HofQ pilQ GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_20461_1 1049564.TevJSym_bc00380 1.34e-177 507.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1JBG6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cysteine-rich domain dgcB - - ko:K21834 - - - - ko00000 - - - CCG,DUF3483,Fer4_8 k141_11394_1 1286106.MPL1_01687 4.92e-48 171.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,460EP@72273|Thiotrichales 72273|Thiotrichales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_11394_2 658187.LDG_8575 6.18e-28 104.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SX88@1236|Gammaproteobacteria,1JEY3@118969|Legionellales 118969|Legionellales G PTS HPr component phosphorylation site ptsH - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_9226_1 1282356.H045_07755 6.83e-64 202.0 COG1028@1|root,COG1028@2|Bacteria,1R6C1@1224|Proteobacteria,1SYUI@1236|Gammaproteobacteria,1YMG8@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_9226_2 1151127.KB906325_gene4591 9.44e-09 55.1 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1YN24@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.39 ko:K00146 ko00360,ko00643,ko01100,ko01120,map00360,map00643,map01100,map01120 - R02536 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_5829_1 1121352.JHZP01000001_gene638 3.36e-83 247.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,2KQVG@206351|Neisseriales 206351|Neisseriales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_5829_2 1120977.JHUX01000003_gene588 5e-05 45.1 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,3NJI9@468|Moraxellaceae 1236|Gammaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_19056_1 458817.Shal_0862 1.56e-36 137.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,2QAS8@267890|Shewanellaceae 1236|Gammaproteobacteria L PFAM phosphoesterase, RecJ domain protein recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_7888_1 314278.NB231_11734 3.36e-43 154.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1X0BD@135613|Chromatiales 135613|Chromatiales S Pfam:UPF0118 - - - - - - - - - - - - AI-2E_transport,Polyketide_cyc k141_5067_2 1286106.MPL1_06507 1.49e-112 328.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales 72273|Thiotrichales Q ABC transporter permease - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_1604_1 1342302.JASC01000013_gene3042 1.64e-06 55.1 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,3ZVH2@60136|Sulfitobacter 28211|Alphaproteobacteria L PD-(D/E)XK nuclease superfamily addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_7173_1 1288826.MSNKSG1_03802 0.0 1357.0 COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,466HF@72275|Alteromonadaceae 1236|Gammaproteobacteria D Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 k141_7173_2 1288826.MSNKSG1_03797 8.78e-55 171.0 2E4HY@1|root,32ZD1@2|Bacteria,1N74N@1224|Proteobacteria,1SCRJ@1236|Gammaproteobacteria,468Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Late competence development protein ComFB - - - - - - - - - - - - ComFB k141_7173_3 1288826.MSNKSG1_03792 2.2e-231 640.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,464N2@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family fadA - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_14872_1 1288826.MSNKSG1_11023 8.44e-122 386.0 COG1800@1|root,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - k141_21810_1 1288826.MSNKSG1_10698 3.31e-78 241.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_21810_2 1288826.MSNKSG1_10693 4.8e-166 465.0 COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,1RN4J@1236|Gammaproteobacteria,465TR@72275|Alteromonadaceae 1236|Gammaproteobacteria M salt-induced outer membrane protein - - - ko:K07283 - - - - ko00000 - - - DUF481 k141_21810_3 1288826.MSNKSG1_10688 2.3e-225 621.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,464ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1722) ybgA - - - - - - - - - - - DUF1722,DUF523 k141_21810_4 1288826.MSNKSG1_10683 2.66e-81 261.0 COG0438@1|root,COG1409@1|root,COG0438@2|Bacteria,COG1409@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,466AT@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 k141_898_1 1278309.KB907104_gene844 3.28e-195 550.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XHN8@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter - - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_21179_1 83406.HDN1F_23070 9.15e-127 387.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1J5DR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N k141_21179_2 472759.Nhal_0882 7.56e-72 219.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales 135613|Chromatiales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_21179_3 1123400.KB904770_gene2712 8.6e-19 81.3 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,4619W@72273|Thiotrichales 72273|Thiotrichales J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_20462_1 1163407.UU7_11522 6.4e-27 105.0 COG0398@1|root,COG0398@2|Bacteria,1PGKM@1224|Proteobacteria,1RXEX@1236|Gammaproteobacteria,1X6AZ@135614|Xanthomonadales 135614|Xanthomonadales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_5068_1 1156919.QWC_14407 4.14e-25 102.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,3T2BE@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_5830_1 1198452.Jab_1c01980 4.39e-62 213.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,475C1@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - DUF2222,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9 k141_2271_1 207954.MED92_15403 1.72e-15 84.3 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XHNH@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_17638_1 1255043.TVNIR_2991 1.75e-23 91.7 COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S765@1236|Gammaproteobacteria,1WYFD@135613|Chromatiales 135613|Chromatiales C ribulose bisphosphate carboxylase, small - - 4.1.1.39 ko:K01602 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_small k141_9928_1 1479238.JQMZ01000001_gene1568 1.32e-40 150.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,43WMM@69657|Hyphomonadaceae 28211|Alphaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg k141_10690_1 870187.Thini_0583 1.36e-38 139.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,460BX@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_10690_2 1279019.ARQK01000029_gene2416 2.91e-20 85.5 COG5626@1|root,COG5626@2|Bacteria,1P5X3@1224|Proteobacteria,1STHD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2288) - - - - - - - - - - - - DUF2288 k141_10690_3 1123518.ARWI01000001_gene381 4.49e-83 256.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,460E4@72273|Thiotrichales 72273|Thiotrichales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_10690_4 1283300.ATXB01000001_gene2456 1.14e-27 100.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1XFSG@135618|Methylococcales 135618|Methylococcales S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p k141_10690_5 349521.HCH_02704 3.57e-40 145.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XIDE@135619|Oceanospirillales 135619|Oceanospirillales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_20463_2 1123399.AQVE01000035_gene3173 1.25e-85 258.0 COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein dsrO - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11,Fer4_7 k141_1605_1 1279019.ARQK01000036_gene1626 3.28e-161 467.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_5831_1 396588.Tgr7_0077 2.06e-56 185.0 COG3221@1|root,COG3221@2|Bacteria,1RGMZ@1224|Proteobacteria,1SZ7V@1236|Gammaproteobacteria,1X2J3@135613|Chromatiales 135613|Chromatiales P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_18330_1 1278309.KB907102_gene32 4.02e-146 426.0 COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria,1XJMI@135619|Oceanospirillales 135619|Oceanospirillales S Putative beta-barrel porin 2 - - - ko:K20920 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.66.3.1,1.B.66.3.2 - - BBP2_2 k141_18330_2 1122599.AUGR01000016_gene2865 4.78e-68 212.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,1XKC2@135619|Oceanospirillales 135619|Oceanospirillales M Polysaccharide biosynthesis/export protein - - - ko:K20988 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_18330_3 1278309.KB907102_gene30 2.46e-50 177.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XI0P@135619|Oceanospirillales 135619|Oceanospirillales D protein involved in exopolysaccharide biosynthesis - - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,GNVR,Wzz k141_17639_1 1120953.AUBH01000001_gene1117 2.3e-36 138.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,4657E@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases fadE GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0217 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_7889_1 1049564.TevJSym_av00160 7.31e-269 748.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_899_1 1168067.JAGP01000001_gene1024 4.74e-67 208.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,460UI@72273|Thiotrichales 72273|Thiotrichales S PFAM Haloacid dehalogenase-like hydrolase - - 3.1.3.105 ko:K22292 ko00520,map00520 - R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_906_5 1288826.MSNKSG1_12482 1.23e-177 495.0 COG1076@1|root,COG1076@2|Bacteria 2|Bacteria O ATPase activator activity djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_906_6 1288826.MSNKSG1_12487 3.57e-61 194.0 28P7Z@1|root,2ZC25@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3530) - - - - - - - - - - - - DUF3530 k141_12085_2 1144319.PMI16_03228 7.83e-38 146.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4730A@75682|Oxalobacteraceae 28216|Betaproteobacteria F DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_3717_1 1278309.KB907108_gene1556 9.55e-193 538.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XH6Q@135619|Oceanospirillales 135619|Oceanospirillales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_4421_1 1458275.AZ34_07565 7.39e-60 196.0 COG0789@1|root,COG0789@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,4ACBQ@80864|Comamonadaceae 28216|Betaproteobacteria K PFAM regulatory protein, MerR - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 k141_5084_1 1122201.AUAZ01000002_gene1078 1.97e-87 270.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,4646X@72275|Alteromonadaceae 1236|Gammaproteobacteria F xanthine xanQ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16345,ko:K16346 - - - - ko00000,ko02000 2.A.40,2.A.40.4.2,2.A.40.4.3 - iG2583_1286.G2583_3536 Xan_ur_permease k141_5084_2 1122201.AUAZ01000002_gene1079 4.06e-100 298.0 COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,1S3EM@1236|Gammaproteobacteria,46DI2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx,DUF5020 k141_5084_3 1442599.JAAN01000037_gene2 5.19e-64 220.0 COG2199@1|root,COG3706@2|Bacteria,1MVCZ@1224|Proteobacteria,1RS2H@1236|Gammaproteobacteria,1X5TB@135614|Xanthomonadales 135614|Xanthomonadales T Diguanylate cyclase - - 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - GGDEF,Protoglobin k141_21829_1 1123368.AUIS01000033_gene1383 6.19e-72 228.0 COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,2NDJP@225057|Acidithiobacillales 225057|Acidithiobacillales C D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_16943_1 84531.JMTZ01000168_gene733 7.05e-57 191.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1X371@135614|Xanthomonadales 135614|Xanthomonadales J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_16943_2 754476.Q7A_2003 2.86e-06 49.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CZB,HAMP,MCPsignal,NIT k141_21194_1 631362.Thi970DRAFT_00019 1.19e-27 104.0 2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,1S9KI@1236|Gammaproteobacteria,1X104@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_21194_2 1122236.KB905141_gene1692 6.22e-18 79.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2VRAZ@28216|Betaproteobacteria,2KMR2@206350|Nitrosomonadales 206350|Nitrosomonadales S Uncharacterized BCR, YaiI/YqxD family COG1671 - - - ko:K09768 - - - - ko00000 - - - DUF188 k141_7181_1 1121033.AUCF01000010_gene4534 2.3e-94 296.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,2JW5J@204441|Rhodospirillales 204441|Rhodospirillales C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Pyr_redox_2 k141_14878_1 573370.DMR_18430 2.54e-49 178.0 COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,43CAA@68525|delta/epsilon subdivisions,2X889@28221|Deltaproteobacteria,2MHD0@213115|Desulfovibrionales 28221|Deltaproteobacteria NT Methyltransferase, chemotaxis proteins - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,PAS,PAS_10 k141_9240_1 251229.Chro_3562 4.63e-135 404.0 COG0033@1|root,COG0033@2|Bacteria,1G0ZB@1117|Cyanobacteria,3VHQS@52604|Pleurocapsales 1117|Cyanobacteria G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_9240_2 977880.RALTA_A1675 8.88e-64 207.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,1K07E@119060|Burkholderiaceae 28216|Betaproteobacteria F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_19720_1 1266914.ATUK01000010_gene1245 1.59e-32 122.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S43R@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_13469_1 207954.MED92_12049 4e-20 89.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XIPG@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_13469_2 1278309.KB907101_gene680 1.23e-195 546.0 COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,1XIA0@135619|Oceanospirillales 135619|Oceanospirillales S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA - - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_13469_3 1278309.KB907101_gene681 1.42e-37 128.0 2ERY1@1|root,31DQ4@2|Bacteria,1QB1H@1224|Proteobacteria,1T6IM@1236|Gammaproteobacteria,1XQRY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_13469_4 1278309.KB907101_gene682 8.23e-35 120.0 COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria,1XM9P@135619|Oceanospirillales 135619|Oceanospirillales S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH k141_2426_1 1366050.N234_05530 5.18e-28 119.0 COG4255@1|root,COG4255@2|Bacteria,1Q1JF@1224|Proteobacteria,2WGEG@28216|Betaproteobacteria,1KG39@119060|Burkholderiaceae 28216|Betaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - k141_2426_2 287.DR97_4153 2.35e-116 352.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1YD0H@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L DHH family recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_3819_1 91464.S7335_4804 2.26e-06 57.8 COG1409@1|root,COG1409@2|Bacteria,1G020@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos k141_12902_1 1278309.KB907111_gene3392 2.44e-25 101.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1XJ3M@135619|Oceanospirillales 135619|Oceanospirillales Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_1050_3 1288826.MSNKSG1_11478 6.36e-135 383.0 COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,1RPWN@1236|Gammaproteobacteria,467HB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Lysine exporter protein LysE YggA rhtB GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K05834 - - - - ko00000,ko02000 2.A.76.1.1 - iECIAI39_1322.ECIAI39_3185 LysE k141_1050_5 1288826.MSNKSG1_11468 1.75e-76 229.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,468A4@72275|Alteromonadaceae 1236|Gammaproteobacteria M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_1050_6 1288826.MSNKSG1_11463 1.43e-62 202.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,464E9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_8088_1 1288826.MSNKSG1_01408 9.24e-70 217.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,466XD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 NUDIX,NUDIX-like,zf-NADH-PPase k141_8088_2 1288826.MSNKSG1_01403 0.0 962.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,464AD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the GPAT DAPAT family plsB GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - iECs_1301.ECs5024,iG2583_1286.G2583_4866 Acyltransferase k141_2440_1 378806.STAUR_5069 3.21e-27 116.0 COG0747@1|root,COG0747@2|Bacteria,1QX9G@1224|Proteobacteria,43C2P@68525|delta/epsilon subdivisions,2X7D9@28221|Deltaproteobacteria,2Z3FQ@29|Myxococcales 28221|Deltaproteobacteria E Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,Peptidase_M36,REJ k141_366_1 571166.KI421509_gene3155 1.33e-66 211.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S integral membrane protein MA20_41380 - - - - - - - - - - - DUF2189 k141_21977_1 1218074.BAXZ01000029_gene4918 9.38e-22 92.4 COG2863@1|root,COG3245@1|root,COG2863@2|Bacteria,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria,1KA8G@119060|Burkholderiaceae 28216|Betaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III nosC - - - - - - - - - - - Cytochrome_CBB3 k141_5211_1 1121403.AUCV01000013_gene3974 3.02e-36 140.0 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MPM4@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine Phosphotransfer domain - - - - - - - - - - - - DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1 k141_5211_2 398767.Glov_1986 1.46e-39 141.0 COG3221@1|root,COG3221@2|Bacteria 2|Bacteria P organic phosphonate transport - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_16339_1 1402135.SUH3_08890 2.08e-184 520.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria,3ZWYJ@60136|Sulfitobacter 28211|Alphaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt k141_10086_1 1121930.AQXG01000001_gene1237 7.7e-61 191.0 COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,1ISRX@117747|Sphingobacteriia 976|Bacteroidetes S Activator of Hsp90 ATPase - - - - - - - - - - - - AHSA1 k141_3180_1 933262.AXAM01000029_gene2747 1.6e-37 131.0 2DNCT@1|root,32WU5@2|Bacteria,1RKZ5@1224|Proteobacteria,42T1G@68525|delta/epsilon subdivisions,2WPD4@28221|Deltaproteobacteria,2MPJX@213118|Desulfobacterales 28221|Deltaproteobacteria C Class III cytochrome C family - - - - - - - - - - - - Cytochrom_CIII k141_9367_1 396588.Tgr7_2462 1.77e-122 367.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_10833_1 686340.Metal_2200 5e-21 102.0 2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_10833_3 1121878.AUGL01000013_gene2877 1.74e-98 301.0 COG3713@1|root,COG3713@2|Bacteria,1MXXC@1224|Proteobacteria,1RYNJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M MltA-interacting MipA family protein - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_19220_1 1232683.ADIMK_3203 1.42e-77 243.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,467K0@72275|Alteromonadaceae 1236|Gammaproteobacteria S AI-2E family transporter perM - - - - - - - - - - - AI-2E_transport k141_18458_1 351016.RAZWK3B_20041 7.25e-94 284.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TSKV@28211|Alphaproteobacteria,2P1I1@2433|Roseobacter 28211|Alphaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) tas GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - - - - - - - - - - Aldo_ket_red k141_5212_1 1347368.HG964408_gene6950 4.21e-51 182.0 COG0642@1|root,COG2199@1|root,COG3300@1|root,COG2205@2|Bacteria,COG3300@2|Bacteria,COG3706@2|Bacteria,1UEIC@1239|Firmicutes,4HDD8@91061|Bacilli,1ZAQA@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_4,PAS_9,Response_reg k141_17067_1 501479.ACNW01000101_gene25 1.74e-36 141.0 COG3637@1|root,COG3637@2|Bacteria,1QV2K@1224|Proteobacteria,2TR2T@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Exopolysaccharide biosynthesis protein YbjH - - - - - - - - - - - - YjbH k141_20611_1 207954.MED92_09636 2.5e-78 235.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1XIXZ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions menG - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like k141_20611_2 1278309.KB907101_gene763 3.51e-67 210.0 COG2227@1|root,COG2227@2|Bacteria,1R2KK@1224|Proteobacteria,1T5S9@1236|Gammaproteobacteria,1XKY1@135619|Oceanospirillales 135619|Oceanospirillales H Tellurite resistance protein TehB - - - - - - - - - - - - - k141_20611_3 1278309.KB907101_gene762 4.21e-35 120.0 2EDE3@1|root,337AE@2|Bacteria,1N7SC@1224|Proteobacteria,1SCUR@1236|Gammaproteobacteria,1XM20@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20611_4 1278309.KB907101_gene761 4.34e-42 153.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XI88@135619|Oceanospirillales 135619|Oceanospirillales C FAD-linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_367_1 177439.DP2299 2.04e-22 91.3 2E8UW@1|root,3335A@2|Bacteria,1N8I8@1224|Proteobacteria,42TGA@68525|delta/epsilon subdivisions,2WQAG@28221|Deltaproteobacteria,2MKHK@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_3181_1 765911.Thivi_4286 1.94e-44 149.0 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales 135613|Chromatiales C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 k141_3181_2 713586.KB900536_gene2898 2.34e-44 155.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_5929_1 1278309.KB907099_gene2870 8.61e-171 485.0 COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria,1XKHP@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF697) - - - ko:K08990 - - - - ko00000 - - - DUF697 k141_5929_2 1278309.KB907099_gene2871 1.85e-281 776.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,1XI2Y@135619|Oceanospirillales 135619|Oceanospirillales S YcjX-like family, DUF463 - - - ko:K06918 - - - - ko00000 - - - DUF463 k141_5929_3 1121948.AUAC01000003_gene2519 7.46e-19 81.6 COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2UG31@28211|Alphaproteobacteria,43YE7@69657|Hyphomonadaceae 28211|Alphaproteobacteria S PQ loop repeat - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - PQ-loop k141_5929_4 616991.JPOO01000003_gene1762 1.07e-17 77.8 COG0346@1|root,COG0346@2|Bacteria,4NT9B@976|Bacteroidetes,1I9Z9@117743|Flavobacteriia 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_6583_1 1278309.KB907106_gene1214 0.0 1051.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XIKC@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_1051_2 1232683.ADIMK_0267 1.88e-117 344.0 COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,1RZJZ@1236|Gammaproteobacteria,46BJ8@72275|Alteromonadaceae 1236|Gammaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_8089_1 553385.JEMF01000016_gene416 3.48e-05 45.4 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase - - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_8089_2 754477.Q7C_1704 1.79e-114 342.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,460BE@72273|Thiotrichales 72273|Thiotrichales EGP major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_19849_1 391615.ABSJ01000055_gene1371 2.7e-112 330.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1J4NY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S NIF3 (NGG1p interacting factor 3) ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - - - - - - - - - - NIF3 k141_12228_1 1278309.KB907099_gene2694 3.61e-193 551.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1XHJ2@135619|Oceanospirillales 135619|Oceanospirillales C Domain of unknown function (DUF3483) - - - ko:K21834 - - - - ko00000 - - - CCG,DUF3483,Fer4_8 k141_2441_1 1158292.JPOE01000002_gene1703 1.35e-99 300.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,1KKWV@119065|unclassified Burkholderiales 28216|Betaproteobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_2441_2 748247.AZKH_p0306 2.4e-75 237.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,2KXTK@206389|Rhodocyclales 206389|Rhodocyclales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_15703_1 545695.TREAZ_0156 1.15e-15 84.0 COG0642@1|root,COG0642@2|Bacteria,2J58F@203691|Spirochaetes 203691|Spirochaetes T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_4,Response_reg,dCache_1 k141_5213_1 754476.Q7A_426 5.76e-65 208.0 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,1RNSP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Exo_endo_phos k141_5213_2 105559.Nwat_1498 9.4e-07 52.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWVI@135613|Chromatiales 135613|Chromatiales K PFAM Cyclic nucleotide-binding - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_8090_1 765910.MARPU_15335 1.8e-44 164.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2,sCache_2 k141_8706_1 1288826.MSNKSG1_11038 3.74e-39 138.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,4666C@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0826 Collagenase and related proteases yhbU - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_8706_2 1288826.MSNKSG1_11043 0.0 938.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQAF@1236|Gammaproteobacteria,466CI@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,NIT k141_8706_3 1288826.MSNKSG1_11048 0.0 955.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,46465@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM k141_8706_4 1288826.MSNKSG1_11053 0.0 1019.0 COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,1RNUM@1236|Gammaproteobacteria,465DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein related to deoxyribodipyrimidine photolyase - - - ko:K06876 - - - - ko00000 - - - DPRP k141_8706_5 1288826.MSNKSG1_11058 0.0 1129.0 COG0546@1|root,COG0546@2|Bacteria,1Q5AX@1224|Proteobacteria,1RRNJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphatases dhlA - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_8706_6 1288826.MSNKSG1_11063 9.94e-75 229.0 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,1S3HN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_10834_1 2340.JV46_26220 1.64e-77 244.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1J4U5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iJN746.PP_0436 S4,tRNA-synt_1b k141_18459_1 631362.Thi970DRAFT_04898 9.66e-157 472.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWAU@135613|Chromatiales 135613|Chromatiales U Hydrophobe Amphiphile Efflux-1 (HAE1) - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_19221_1 351016.RAZWK3B_06847 7.78e-48 164.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2P2FE@2433|Roseobacter 28211|Alphaproteobacteria S Zn-dependent proteases and their inactivated homologs tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_10087_2 555778.Hneap_1380 3.8e-47 153.0 COG2329@1|root,COG2329@2|Bacteria,1QCV7@1224|Proteobacteria,1SDHZ@1236|Gammaproteobacteria,1WZBS@135613|Chromatiales 135613|Chromatiales C PFAM Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_10087_3 1159870.KB907784_gene3270 1.88e-31 124.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,3T1I1@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_12229_1 1380367.JIBC01000006_gene312 1.55e-27 113.0 2E5UU@1|root,330J2@2|Bacteria,1N96G@1224|Proteobacteria,2UIMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12919_1 396588.Tgr7_3044 7.58e-09 55.5 COG0515@1|root,COG0515@2|Bacteria,1NUIB@1224|Proteobacteria 1224|Proteobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase k141_12919_2 595460.RRSWK_04882 1.16e-67 218.0 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_12919_3 985867.AEWF01000003_gene892 2.02e-11 62.4 COG0695@1|root,COG0695@2|Bacteria 2|Bacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Glutaredoxin,Pyr_redox_2,Response_reg k141_12919_4 1485544.JQKP01000014_gene1873 4.76e-36 151.0 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44VCS@713636|Nitrosomonadales 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS_9,dCache_1 k141_12919_5 983545.Glaag_0651 5.25e-65 204.0 COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,466RV@72275|Alteromonadaceae 1236|Gammaproteobacteria M lipocalin blc GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_15704_1 1123392.AQWL01000003_gene148 2.5e-21 91.7 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,1KSKW@119069|Hydrogenophilales 119069|Hydrogenophilales KO CobW/HypB/UreG, nucleotide-binding domain - - - - - - - - - - - - cobW k141_5214_1 1121396.KB893076_gene706 1.21e-27 107.0 COG3501@1|root,COG3501@2|Bacteria,1R540@1224|Proteobacteria,42Q1X@68525|delta/epsilon subdivisions,2WM75@28221|Deltaproteobacteria,2MNWA@213118|Desulfobacterales 28221|Deltaproteobacteria S Baseplate assembly protein - - - - - - - - - - - - - k141_5214_2 269799.Gmet_1137 6.6e-34 128.0 COG3500@1|root,COG3500@2|Bacteria,1QK0F@1224|Proteobacteria,42T0N@68525|delta/epsilon subdivisions,2WPW1@28221|Deltaproteobacteria,43VVG@69541|Desulfuromonadales 28221|Deltaproteobacteria S Late control gene D protein - - - - - - - - - - - - - k141_19850_1 296591.Bpro_3587 1.2e-82 253.0 COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2VHSZ@28216|Betaproteobacteria,4AANF@80864|Comamonadaceae 28216|Betaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_16340_1 765914.ThisiDRAFT_0321 5.08e-14 79.3 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WXHR@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k141_16340_2 1123401.JHYQ01000007_gene501 1.6e-67 210.0 COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,1S1KD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphoesterase - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_10088_1 1479237.JMLY01000001_gene1041 1.31e-31 127.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,46632@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain pleD - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_6585_1 1168067.JAGP01000001_gene1494 2.9e-56 176.0 COG2863@1|root,COG2863@2|Bacteria 2|Bacteria C cytochrome cccB - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_2442_2 1163409.UUA_15166 6.47e-24 97.4 COG1622@1|root,COG1622@2|Bacteria,1RHZD@1224|Proteobacteria,1S7HV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM Cytochrome C oxidase subunit II - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 k141_15705_1 472759.Nhal_1179 1.46e-54 177.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1WXT6@135613|Chromatiales 135613|Chromatiales I PFAM phosphoesterase PA-phosphatase related - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_8092_1 1288826.MSNKSG1_06233 2.34e-54 180.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,464DX@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_8092_2 1288826.MSNKSG1_06238 8.82e-89 266.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,465C9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_12920_1 187272.Mlg_0245 2.57e-63 203.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_12920_2 216142.LT40_05015 1.57e-06 48.1 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein tolR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_5215_1 290512.Paes_0785 2.6e-72 241.0 COG2274@1|root,COG2274@2|Bacteria,1FEM5@1090|Chlorobi 1090|Chlorobi V TIGRFAM type I secretion system ATPase - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran k141_16341_1 1382304.JNIL01000001_gene307 1.45e-51 182.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,27813@186823|Alicyclobacillaceae 91061|Bacilli KT Sigma-54 interaction domain bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_21978_1 338963.Pcar_3052 1.37e-132 401.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_20612_1 1288826.MSNKSG1_09653 1.39e-162 466.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit phaD - 1.6.5.3 ko:K00342,ko:K05561,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M k141_20612_2 1288826.MSNKSG1_09658 4.79e-108 311.0 COG1863@1|root,COG1863@2|Bacteria,1N1SJ@1224|Proteobacteria,1SPTK@1236|Gammaproteobacteria,46D0Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1863 Multisubunit Na H antiporter, MnhE subunit phaE - - ko:K05562 - - - - ko00000,ko02000 2.A.63.1 - - MNHE k141_19851_2 1123519.PSJM300_04080 8.65e-40 140.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1Z1U6@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_15857_9 1288826.MSNKSG1_09803 1.17e-167 472.0 2EMFB@1|root,33F44@2|Bacteria,1NH7D@1224|Proteobacteria,1SGY2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2059) - - - - - - - - - - - - DUF2059 k141_15857_10 1288826.MSNKSG1_09798 2.07e-225 625.0 COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,1RRV8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Beta-lactamase superfamily domain rnz - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - CLP1_P,Lactamase_B,Lactamase_B_2 k141_15857_11 1288826.MSNKSG1_09793 8.5e-286 780.0 COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,4658E@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_15857_12 1288826.MSNKSG1_09788 1.41e-60 186.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,467WN@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0760 Parvulin-like peptidyl-prolyl isomerase ppiC - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_6031_1 497964.CfE428DRAFT_3886 1.34e-39 144.0 COG4124@1|root,COG4124@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k141_2564_1 1288826.MSNKSG1_13817 5.47e-177 496.0 COG0583@1|root,COG0583@2|Bacteria,1QN6R@1224|Proteobacteria,1RSKY@1236|Gammaproteobacteria,466I6@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_2564_2 270374.MELB17_05057 4.16e-28 105.0 2E5B0@1|root,33033@2|Bacteria,1ND0X@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_2564_3 1288826.MSNKSG1_13807 2.08e-308 857.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,4657E@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases fadE - 1.3.8.7 ko:K00249,ko:K06445 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_16516_1 357804.Ping_2411 2.17e-124 381.0 COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria T EAL domain - - - - - - - - - - - - CBS,EAL,GGDEF k141_16516_3 519989.ECTPHS_01494 2.84e-29 112.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1WWD5@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_13075_1 243233.MCA1415 1.09e-111 333.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1XE66@135618|Methylococcales 135618|Methylococcales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_515_1 1278309.KB907108_gene1563 6.75e-134 384.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XIGK@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_15105_1 1123355.JHYO01000004_gene2464 3.92e-36 134.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2U2AJ@28211|Alphaproteobacteria,36YJZ@31993|Methylocystaceae 28211|Alphaproteobacteria T HD domain - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k141_17958_1 754477.Q7C_315 1.64e-99 300.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,45ZQI@72273|Thiotrichales 72273|Thiotrichales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_5400_1 472759.Nhal_3150 1.43e-60 192.0 COG0569@1|root,COG0569@2|Bacteria,1RDDX@1224|Proteobacteria,1S3ZR@1236|Gammaproteobacteria,1WY9A@135613|Chromatiales 135613|Chromatiales C TrkA-N domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_5400_2 472759.Nhal_3151 4.3e-142 424.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WXFD@135613|Chromatiales 135613|Chromatiales P PFAM Cation - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_5400_4 1121918.ARWE01000001_gene527 5.93e-24 99.0 COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,43SQU@69541|Desulfuromonadales 28221|Deltaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - AsmA k141_17214_1 1123360.thalar_01860 7.08e-77 241.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_21441_1 754476.Q7A_1593 4.94e-80 246.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,460KN@72273|Thiotrichales 72273|Thiotrichales S of the beta-lactamase superfamily I - - - - - - - - - - - - Lactamase_B_2 k141_8217_1 2340.JV46_04110 2.15e-55 174.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1J6FZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053 Fe-S_biosyn k141_8217_2 1168065.DOK_07414 2.16e-10 60.5 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1J6NP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_15858_1 1278309.KB907102_gene4 7.14e-104 311.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XI8P@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_3949_1 1458275.AZ34_10625 7.8e-62 205.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,4AABZ@80864|Comamonadaceae 28216|Betaproteobacteria T GAF domain - - - - - - - - - - - - GAF,HD,HD_5 k141_3949_2 455436.DS989810_gene168 1.17e-07 53.5 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,1S3KS@1236|Gammaproteobacteria,466K1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - CbiM k141_13076_1 357804.Ping_1500 4.34e-13 70.1 COG2304@1|root,COG2304@2|Bacteria,1RADV@1224|Proteobacteria,1S5N1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - VPEP,VWA_2 k141_8802_1 1278309.KB907104_gene841 7.92e-81 242.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XJME@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - MarR k141_8802_2 1278309.KB907104_gene842 1.78e-112 330.0 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,1RQ3U@1236|Gammaproteobacteria,1XIM7@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter substrate-binding protein - - - - - - - - - - - - OpuAC k141_12394_1 1208321.D104_09840 5.45e-83 264.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1T1KQ@1236|Gammaproteobacteria,1XN2T@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K07649 ko02020,map02020 M00457 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_16517_2 1123247.AUIJ01000004_gene1000 2.95e-42 142.0 2BC1V@1|root,325KI@2|Bacteria,1MYPW@1224|Proteobacteria,2USD5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_10973_1 1461693.ATO10_05087 9.34e-07 50.4 COG0500@1|root,COG2226@2|Bacteria,1NA7K@1224|Proteobacteria,2TT7T@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Methyltransferase MA20_39625 - - - - - - - - - - - Methyltransf_11 k141_10973_2 1123360.thalar_00907 1.78e-31 116.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_15859_1 426114.THI_2411 2.73e-87 269.0 COG0446@1|root,COG0446@2|Bacteria,1QSG7@1224|Proteobacteria,2W9DB@28216|Betaproteobacteria,1KKDR@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_13763_1 95619.PM1_0222565 1.45e-57 189.0 COG1131@1|root,COG1131@2|Bacteria,1MX56@1224|Proteobacteria,1S0C7@1236|Gammaproteobacteria 1236|Gammaproteobacteria V transporter atp-binding protein pedB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_13763_2 864051.BurJ1DRAFT_1108 4.52e-14 79.3 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VM1W@28216|Betaproteobacteria,1KK7W@119065|unclassified Burkholderiales 28216|Betaproteobacteria S 40-residue YVTN family beta-propeller repeat - - - - - - - - - - - - Cytochrom_D1,Lactonase k141_19361_2 1278309.KB907099_gene3060 4.21e-152 429.0 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,1RQZM@1236|Gammaproteobacteria,1XI4N@135619|Oceanospirillales 135619|Oceanospirillales E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_19361_3 1278309.KB907099_gene3061 1.42e-252 697.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RY3R@1236|Gammaproteobacteria,1XI01@135619|Oceanospirillales 135619|Oceanospirillales E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_19361_4 1278309.KB907099_gene3062 3.84e-141 403.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,1SYK4@1236|Gammaproteobacteria,1XJ2X@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_536_1 891968.Anamo_1881 4.42e-31 125.0 COG0463@1|root,COG1807@1|root,COG2246@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,COG2246@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process MA20_09515 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2,GtrA,PMT_2 k141_536_2 1128421.JAGA01000002_gene1279 1.65e-06 56.6 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_21453_1 345073.VC395_A1078 2.45e-65 210.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1XTV8@135623|Vibrionales 135623|Vibrionales K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_6050_1 187272.Mlg_0945 6.45e-69 218.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_6050_2 187272.Mlg_0946 4.16e-07 48.9 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1WZRT@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_13783_1 396588.Tgr7_2407 3.5e-63 207.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1WXXP@135613|Chromatiales 135613|Chromatiales O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_13783_2 1411685.U062_02115 1.11e-106 352.0 COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T (GGDEF) domain - - - - - - - - - - - - DUF2222,EAL,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg k141_12414_2 396588.Tgr7_1802 1.17e-68 214.0 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1WYF0@135613|Chromatiales 135613|Chromatiales L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_8815_1 1278309.KB907102_gene182 6.19e-93 278.0 COG2384@1|root,COG2384@2|Bacteria,1RBQ3@1224|Proteobacteria,1S2DU@1236|Gammaproteobacteria,1XKCI@135619|Oceanospirillales 135619|Oceanospirillales S tRNA (adenine(22)-N(1))-methyltransferase - - 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_18 k141_8815_2 1232683.ADIMK_3874 5.24e-263 728.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,464J5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF k141_13086_1 1278309.KB907104_gene970 9.15e-45 149.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1XKST@135619|Oceanospirillales 135619|Oceanospirillales I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_13086_2 1278309.KB907104_gene971 8.56e-214 594.0 COG1819@1|root,COG1819@2|Bacteria,1QVV0@1224|Proteobacteria,1RQBP@1236|Gammaproteobacteria 1236|Gammaproteobacteria CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - - - - - - - - - - Glyco_trans_1_3 k141_15119_1 1278309.KB907111_gene3398 2.34e-147 420.0 COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,1XHYR@135619|Oceanospirillales 135619|Oceanospirillales P Ion transporter - - - ko:K08714 - - - - ko00000,ko02000 1.A.1.14 - - Ion_trans k141_10260_1 744980.TRICHSKD4_0438 3.76e-63 206.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TRHD@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_7493_1 1249480.B649_09935 5.87e-41 150.0 COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42Q8D@68525|delta/epsilon subdivisions,2YMC5@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Glycosyl transferases group 1 pglH1 - 2.4.1.292 ko:K17249 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 k141_22112_2 1283300.ATXB01000002_gene2682 1.87e-12 67.8 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1XE8H@135618|Methylococcales 135618|Methylococcales P PFAM Binding-protein-dependent transport systems inner membrane component - - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_17985_1 323848.Nmul_A0045 6.14e-99 322.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales 28216|Betaproteobacteria H Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_13087_1 400668.Mmwyl1_2685 1.56e-69 228.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XHEU@135619|Oceanospirillales 135619|Oceanospirillales S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM k141_18621_1 317025.Tcr_1261 7.58e-70 218.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales 72273|Thiotrichales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_18621_2 396588.Tgr7_1184 1.7e-52 178.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1WVX6@135613|Chromatiales 135613|Chromatiales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_12415_1 550540.Fbal_2613 3.8e-22 97.4 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_5417_1 1469613.JT55_01920 9.35e-99 291.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,3FD8E@34008|Rhodovulum 28211|Alphaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_3960_1 1278309.KB907100_gene1911 1.74e-169 474.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XHIU@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_3960_2 1278309.KB907100_gene1910 3.14e-72 218.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1XJT2@135619|Oceanospirillales 135619|Oceanospirillales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_19362_1 1121033.AUCF01000018_gene5800 7.41e-22 97.4 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U1PX@28211|Alphaproteobacteria,2JRDE@204441|Rhodospirillales 204441|Rhodospirillales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_17986_1 1122137.AQXF01000002_gene262 3.29e-108 314.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_22113_2 1304865.JAGF01000001_gene738 7.05e-10 59.3 COG3677@1|root,COG3677@2|Bacteria,2IF2C@201174|Actinobacteria 201174|Actinobacteria L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_16530_1 1396858.Q666_03950 4.86e-114 338.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RYGT@1236|Gammaproteobacteria,466BG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit benA - 1.14.12.10 ko:K05549 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k141_7494_1 1278309.KB907108_gene1596 2.28e-109 327.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIZ6@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_7494_2 1232683.ADIMK_0303 5.71e-06 47.4 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria,46533@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - 4.2.1.132,4.2.1.80 ko:K18364 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02601,R05864 RC00750,RC02676 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_13088_1 1278309.KB907102_gene8 2.83e-24 101.0 COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,1XIRH@135619|Oceanospirillales 135619|Oceanospirillales M O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_13785_1 34506.g2384 6.84e-44 165.0 COG0688@1|root,KOG2420@2759|Eukaryota,38E13@33154|Opisthokonta,3BDPJ@33208|Metazoa,3CU2W@33213|Bilateria,40DQU@6231|Nematoda,1KWBC@119089|Chromadorea,40SSW@6236|Rhabditida 33208|Metazoa I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine psd-1 - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_15120_1 1288826.MSNKSG1_16251 2.61e-90 273.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,466KI@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_15120_2 1288826.MSNKSG1_16256 3.9e-45 162.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4663R@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_15874_2 298386.PBPRB0649 3.11e-69 216.0 COG1143@1|root,COG1245@1|root,COG1143@2|Bacteria,COG1245@2|Bacteria,1QW0T@1224|Proteobacteria,1T38G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Ferredoxin-type protein napG of Proteobacteria UniRef RepID napG - - ko:K02573 - - - - ko00000 - - - Fer4,Fer4_4,Fer4_7 k141_2581_1 243233.MCA3079 2.15e-104 316.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XED6@135618|Methylococcales 135618|Methylococcales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM k141_11663_1 661367.LLO_0322 5.31e-51 176.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1JCX6@118969|Legionellales 118969|Legionellales H HemY protein N-terminus hemY - - ko:K02498 - - - - ko00000 - - - HemY_N k141_11663_2 1121943.KB899996_gene451 1.74e-48 174.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XH3M@135619|Oceanospirillales 135619|Oceanospirillales H enzyme of heme biosynthesis hemX - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX k141_18622_2 1380387.JADM01000002_gene2068 6.77e-42 141.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1XPEX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_18622_3 1122134.KB893650_gene1602 1.37e-11 64.3 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_3961_1 1121403.AUCV01000014_gene4654 1.81e-64 217.0 COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,42PU1@68525|delta/epsilon subdivisions,2X5K4@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_3327_1 765912.Thimo_2947 0.0 895.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WWEJ@135613|Chromatiales 135613|Chromatiales G RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site cbbL - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_7495_1 1216007.AOPM01000057_gene1870 1.88e-17 75.9 2EK53@1|root,33DVI@2|Bacteria,1NGEE@1224|Proteobacteria,1SH0A@1236|Gammaproteobacteria,2Q3D6@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6051_1 1122212.AULO01000008_gene1319 2.72e-55 191.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XI2V@135619|Oceanospirillales 135619|Oceanospirillales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_6051_2 1278309.KB907101_gene626 2.72e-31 111.0 2BJG7@1|root,32DSX@2|Bacteria,1QSY3@1224|Proteobacteria,1RWK4@1236|Gammaproteobacteria,1XM92@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6051_3 1278309.KB907101_gene625 1.17e-100 309.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XITH@135619|Oceanospirillales 135619|Oceanospirillales E ABC-type oligopeptide transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_20050_1 999549.KI421513_gene2046 1.52e-115 342.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,28011@191028|Leisingera 28211|Alphaproteobacteria M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_21592_1 159450.NH14_26545 6.98e-27 110.0 28IJW@1|root,2Z8KR@2|Bacteria,1R45I@1224|Proteobacteria,2VK7H@28216|Betaproteobacteria,1K2GY@119060|Burkholderiaceae 28216|Betaproteobacteria S signal peptide protein - - - - - - - - - - - - - k141_7614_1 1121935.AQXX01000142_gene2266 1.02e-05 46.2 2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7614_2 1278309.KB907107_gene1764 9.51e-24 99.0 COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,1XHDX@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI k141_649_1 313595.P700755_003006 1.68e-40 142.0 COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1HYUA@117743|Flavobacteriia 976|Bacteroidetes M mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_649_2 1313421.JHBV01000005_gene4555 4.72e-29 111.0 COG2207@1|root,COG2207@2|Bacteria,4NJNH@976|Bacteroidetes,1J040@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional regulator, AraC family - - - - - - - - - - - - AraC_binding,HTH_18 k141_4018_1 1278309.KB907099_gene2704 1.85e-60 196.0 COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,1RRPT@1236|Gammaproteobacteria,1XH5A@135619|Oceanospirillales 135619|Oceanospirillales E Alcohol dehydrogenase GroES-like domain fdhA - 1.2.1.46 ko:K00148 ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200 - R00604 RC00188 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_6207_1 207954.MED92_09753 1.31e-60 189.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XJR3@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_6207_2 1279019.ARQK01000031_gene1204 2.34e-10 61.2 COG4319@1|root,COG4319@2|Bacteria,1NEUY@1224|Proteobacteria,1S6AP@1236|Gammaproteobacteria,1WYK1@135613|Chromatiales 135613|Chromatiales S SnoaL-like domain - - - - - - - - - - - - SnoaL_3 k141_10448_1 2340.JV46_04650 1.38e-120 357.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos k141_2727_1 795666.MW7_2223 5.37e-09 63.9 COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria,1K1E0@119060|Burkholderiaceae 28216|Betaproteobacteria U general secretion pathway protein K gspK - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_16665_1 998674.ATTE01000001_gene4007 9.44e-72 233.0 COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,463U2@72273|Thiotrichales 72273|Thiotrichales V ABC transporter - - - ko:K13926 - - - - ko00000 - - - ABC2_membrane_3,ABC_tran k141_15200_3 220664.PFL_2675 4.7e-48 180.0 2CBEQ@1|root,346ZE@2|Bacteria,1P20Y@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_15200_4 322710.Avin_45580 1.84e-42 146.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1SAV7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_17358_1 1278309.KB907099_gene2897 1.36e-20 86.7 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440,SnoaL_2 k141_17358_2 1278309.KB907099_gene2896 6.77e-117 342.0 COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,1RSHH@1236|Gammaproteobacteria,1XIVU@135619|Oceanospirillales 135619|Oceanospirillales S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_2015_1 566466.NOR53_1144 3.03e-19 85.1 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1J4MQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_2015_2 519989.ECTPHS_05325 8.4e-105 315.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1WW43@135613|Chromatiales 135613|Chromatiales J TIGRFAM Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_16026_1 1123518.ARWI01000001_gene400 2.82e-171 502.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_6208_1 1123247.AUIJ01000001_gene1695 1.52e-41 150.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria 28211|Alphaproteobacteria C FAD linked oxidase - - 1.1.3.8,1.1.98.3 ko:K00103,ko:K16653 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 k141_6208_2 633131.TR2A62_1874 1.2e-58 189.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2TTWH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MA20_24385 - - - - - - - - - - - adh_short k141_650_1 272624.lpg2613 9.12e-95 288.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1JCPX@118969|Legionellales 118969|Legionellales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_10449_2 279383.Q5DN91_9CAUD 7.08e-127 381.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k141_7615_2 1116472.MGMO_45c00410 1.31e-37 132.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XEZ1@135618|Methylococcales 135618|Methylococcales J Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_16666_1 999141.GME_04327 1.29e-108 324.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XH6Q@135619|Oceanospirillales 135619|Oceanospirillales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_20052_1 1109445.AGSX01000133_gene2853 1.64e-29 115.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1Z1T0@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_20052_2 1177154.Y5S_01032 3.01e-40 143.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1XJRF@135619|Oceanospirillales 135619|Oceanospirillales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_7616_1 768671.ThimaDRAFT_4416 6.13e-73 233.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1X036@135613|Chromatiales 135613|Chromatiales P NMT1-like family - - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_651_1 278963.ATWD01000001_gene1915 5.76e-32 121.0 COG3271@1|root,COG3271@2|Bacteria 2|Bacteria - - - - - ko:K06992 - - - - ko00000 - - - DUF3335,Peptidase_C39 k141_6209_1 203122.Sde_0798 5.14e-36 143.0 COG0747@1|root,COG2356@1|root,COG2911@1|root,COG2982@1|root,COG3210@1|root,COG3506@1|root,COG3637@1|root,COG0747@2|Bacteria,COG2356@2|Bacteria,COG2911@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,1P8N9@1224|Proteobacteria,1SCTK@1236|Gammaproteobacteria,46D2E@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cadherin repeats. - - - - - - - - - - - - Cadherin,DUF4347,DUF5122,He_PIG,OmpA_membrane k141_2728_1 391615.ABSJ01000026_gene110 4.5e-63 210.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding k141_18787_1 1278309.KB907101_gene568 1.33e-57 185.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_18787_2 1278309.KB907101_gene567 5.55e-38 127.0 2E5VJ@1|root,330JM@2|Bacteria,1NBMJ@1224|Proteobacteria,1SDR6@1236|Gammaproteobacteria,1XMCU@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_18787_3 1278309.KB907101_gene566 1.25e-127 367.0 COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,1S406@1236|Gammaproteobacteria,1XJI7@135619|Oceanospirillales 135619|Oceanospirillales J Pseudouridine synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_18787_5 1278309.KB907101_gene564 1.94e-109 318.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1XJ85@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DnaA family. HdA subfamily - - - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_2017_2 1448139.AI20_18665 9.12e-57 184.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1Y3ZZ@135624|Aeromonadales 135624|Aeromonadales M Glycosyl transferase family 2 - - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 k141_8973_3 228410.NE0609 3.82e-218 615.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,3720Y@32003|Nitrosomonadales 28216|Betaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_8973_4 290397.Adeh_0828 4.78e-78 237.0 COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin k141_8973_5 1249627.D779_3935 1.31e-217 612.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P k141_9650_2 1288826.MSNKSG1_12007 2.96e-167 469.0 COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,1RR15@1236|Gammaproteobacteria,4676K@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_9650_3 1288826.MSNKSG1_12012 7.19e-216 598.0 COG0715@1|root,COG0715@2|Bacteria,1MWUA@1224|Proteobacteria,1S2B3@1236|Gammaproteobacteria,467C0@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,SBP_bac_3 k141_9650_4 1288826.MSNKSG1_12017 7.93e-172 481.0 COG2197@1|root,COG2197@2|Bacteria,1PXTY@1224|Proteobacteria,1RMPW@1236|Gammaproteobacteria,466JI@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain agmR - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_9650_5 1288826.MSNKSG1_12022 0.0 1399.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTVB@1224|Proteobacteria,1RYDJ@1236|Gammaproteobacteria,464AX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase pedS1 - 2.7.13.3 ko:K20975 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_7,PAS_8,Response_reg k141_9650_6 1288826.MSNKSG1_12027 2.05e-275 755.0 COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria,465QT@72275|Alteromonadaceae 1236|Gammaproteobacteria NT FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_9650_7 1288826.MSNKSG1_12032 5.89e-256 702.0 COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,1S09X@1236|Gammaproteobacteria,469DM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_9650_8 1288826.MSNKSG1_12037 2.59e-199 560.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1SMIE@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf k141_15202_1 195105.CN97_08920 6.95e-13 67.8 COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,2TR3K@28211|Alphaproteobacteria 28211|Alphaproteobacteria M murein endopeptidase mepA - - ko:K07261 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M74 k141_15202_2 83219.PM02_07115 7.47e-43 152.0 COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,3ZWXK@60136|Sulfitobacter 28211|Alphaproteobacteria S Esterase-like activity of phytase - - - - - - - - - - - - Phytase-like k141_16667_1 1278309.KB907100_gene2021 5.07e-172 483.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,1XIJQ@135619|Oceanospirillales 135619|Oceanospirillales K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_10450_2 1255043.TVNIR_3223 8.94e-211 588.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1WWXU@135613|Chromatiales 135613|Chromatiales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_10450_3 1286106.MPL1_05197 1.26e-32 117.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,460NY@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM Acetolactate synthase, small subunit - - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C k141_3483_1 399741.Spro_0065 2.35e-13 77.4 COG3240@1|root,COG5571@1|root,COG3240@2|Bacteria,COG5571@2|Bacteria,1MWDI@1224|Proteobacteria,1SYGP@1236|Gammaproteobacteria,4027D@613|Serratia 1236|Gammaproteobacteria IN GDSL-like Lipase/Acylhydrolase lip-1 - - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k141_3483_2 1288826.MSNKSG1_11168 0.0 1066.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4640N@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_3483_3 1288826.MSNKSG1_11163 4.36e-178 503.0 COG3213@1|root,COG3213@2|Bacteria,1RE7Q@1224|Proteobacteria,1S3UC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P protein involved in response to NO - - - - - - - - - - - - NnrS k141_15203_1 511062.GU3_07700 2.26e-07 51.2 COG0583@1|root,COG0583@2|Bacteria,1R49T@1224|Proteobacteria,1SYGQ@1236|Gammaproteobacteria,1Y4P0@135624|Aeromonadales 135624|Aeromonadales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_6211_1 395961.Cyan7425_0749 4.87e-25 105.0 COG2199@1|root,COG3706@2|Bacteria 2|Bacteria T GGDEF domain - - - - - - - - - - - - HisKA,PAS_8,PAS_9,Response_reg,SpoIIE k141_3484_1 391589.RGAI101_1421 2.43e-27 106.0 COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,2P1V0@2433|Roseobacter 28211|Alphaproteobacteria G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family suhB2 - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_3484_2 314270.RB2083_1384 2.46e-36 133.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,3ZGKF@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Zn-dependent proteases and their inactivated homologs pmbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_4023_1 1280953.HOC_19306 4.45e-29 112.0 COG2761@1|root,COG2761@2|Bacteria,1REE7@1224|Proteobacteria,2URMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q DSBA-like thioredoxin domain - - - - - - - - - - - - DSBA k141_4878_1 160488.PP_0933 2.47e-39 140.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1YV26@136845|Pseudomonas putida group 1236|Gammaproteobacteria D TIGRFAM Cell shape determining protein MreB Mrl mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_4878_2 1278309.KB907099_gene2375 4.5e-167 471.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XHGW@135619|Oceanospirillales 135619|Oceanospirillales M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_4878_3 1278309.KB907099_gene2376 5.35e-98 286.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1XJS0@135619|Oceanospirillales 135619|Oceanospirillales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_4878_4 1112217.PPL19_05765 2.11e-63 202.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria 1236|Gammaproteobacteria D maF-like protein yhdE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_4878_5 1278309.KB907099_gene2378 1.45e-17 80.9 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XI2S@135619|Oceanospirillales 135619|Oceanospirillales J Involved in the processing of the 5'end of 16S rRNA - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_16668_1 1173027.Mic7113_2828 2.35e-23 107.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales 1117|Cyanobacteria T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_16027_1 1278309.KB907099_gene2833 5.51e-41 146.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1XHDG@135619|Oceanospirillales 135619|Oceanospirillales T ATPase related to phosphate starvation-inducible protein PhoH phoH1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_16027_2 1278309.KB907099_gene2834 2.21e-142 404.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1XIDW@135619|Oceanospirillales 135619|Oceanospirillales K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_16027_3 1278309.KB907099_gene2835 1.71e-202 568.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XHP4@135619|Oceanospirillales 135619|Oceanospirillales S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k141_20824_1 1123228.AUIH01000004_gene1132 1.8e-10 63.5 2DQ9F@1|root,335FN@2|Bacteria,1NEEU@1224|Proteobacteria,1SGG8@1236|Gammaproteobacteria,1XMMP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2489) - - - - - - - - - - - - DUF2489 k141_20824_2 1278309.KB907108_gene1637 2.82e-55 175.0 2ENIU@1|root,3384E@2|Bacteria,1N886@1224|Proteobacteria,1SCUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20824_3 1278309.KB907108_gene1636 0.0 960.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07678,ko:K20974 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475,M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE3,DUF2222,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_7617_1 521719.ATXQ01000010_gene41 4.3e-187 531.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase - - - - - - - - - - - - Fer4_14 k141_7617_2 1190606.AJYG01000201_gene1241 7.66e-48 170.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XTFN@135623|Vibrionales 135623|Vibrionales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_6212_1 1286106.MPL1_01149 4.4e-47 168.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,4608V@72273|Thiotrichales 72273|Thiotrichales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CBS,EAL,GGDEF k141_22277_1 1121035.AUCH01000015_gene2620 0.000201 48.9 COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,1QU09@1224|Proteobacteria,2WGS7@28216|Betaproteobacteria,2KWTJ@206389|Rhodocyclales 206389|Rhodocyclales M Outer membrane adhesin like proteiin - - - - - - - - - - - - - k141_9008_1 765910.MARPU_00320 8.27e-119 348.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1WWD5@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_20064_2 420662.Mpe_A0067 3.53e-24 101.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,1KJ7M@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_11772_1 1283300.ATXB01000001_gene1032 1.11e-104 317.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XEQ5@135618|Methylococcales 135618|Methylococcales H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_17381_1 1504981.KO116_2980 3.13e-91 287.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XS2D@135619|Oceanospirillales 135619|Oceanospirillales KT Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - PAS_9,Sigma54_activat k141_2747_1 105559.Nwat_2327 1.77e-195 553.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1X07Y@135613|Chromatiales 135613|Chromatiales E TIGRFAM amidase, hydantoinase carbamoylase - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_9009_1 685778.AORL01000010_gene3131 5.47e-38 142.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,2K246@204457|Sphingomonadales 204457|Sphingomonadales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 k141_6239_1 1163617.SCD_n02656 2.89e-28 110.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria 28216|Betaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_6239_2 375286.mma_3148 3.09e-11 60.1 2E53D@1|root,32ZWH@2|Bacteria,1N979@1224|Proteobacteria,2VVRY@28216|Betaproteobacteria,4750N@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 k141_6239_3 472759.Nhal_0064 8.02e-141 405.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1WX89@135613|Chromatiales 135613|Chromatiales C PFAM cytochrome c oxidase, subunit III - - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_16106_1 1122201.AUAZ01000037_gene3847 4.01e-63 209.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,468GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_16106_2 1278309.KB907100_gene1945 7.96e-60 186.0 COG3171@1|root,COG3171@2|Bacteria,1QTPU@1224|Proteobacteria,1RXU9@1236|Gammaproteobacteria,1XQR8@135619|Oceanospirillales 135619|Oceanospirillales S Protein with unknown function (DUF469) - - - - - - - - - - - - DUF469 k141_16106_3 1278309.KB907100_gene1944 2.11e-95 279.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1XJRT@135619|Oceanospirillales 135619|Oceanospirillales O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB k141_16106_4 1415778.JQMM01000001_gene970 1.43e-34 129.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1J5IR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family IV02_29000 - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_8446_1 1123354.AUDR01000015_gene464 2.51e-33 128.0 COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2VJX1@28216|Betaproteobacteria 28216|Betaproteobacteria H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_8446_2 269796.Rru_A3228 6.43e-19 85.5 COG2867@1|root,COG2867@2|Bacteria,1PPRM@1224|Proteobacteria,2UJ52@28211|Alphaproteobacteria,2JU9G@204441|Rhodospirillales 204441|Rhodospirillales I Polyketide cyclase / dehydrase and lipid transport - - - ko:K18588 - - - - ko00000 - - - Polyketide_cyc k141_19595_1 2340.JV46_16010 3.67e-142 422.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,1RPSF@1236|Gammaproteobacteria,1JC0D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Acetyl-coenzyme A transporter 1 ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 k141_19595_2 1265313.HRUBRA_00798 2.75e-122 365.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1J5K7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion macA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_19595_3 563008.HMPREF0665_01171 2.17e-20 88.2 COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,2FPB3@200643|Bacteroidia 976|Bacteroidetes V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_21055_1 159450.NH14_30365 9.36e-39 151.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1K2HP@119060|Burkholderiaceae 28216|Betaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF2 - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_16820_1 1255043.TVNIR_2230 3.8e-50 172.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RN94@1236|Gammaproteobacteria,1WXKU@135613|Chromatiales 135613|Chromatiales S PFAM Radical SAM - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM k141_16820_2 396588.Tgr7_1958 8.24e-65 207.0 COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria,1WYEW@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_5700_1 1123053.AUDG01000003_gene2667 1.84e-09 58.9 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1WWCM@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_5700_2 472759.Nhal_0576 1.07e-72 227.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_19617_2 1278309.KB907110_gene3160 8.3e-203 563.0 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1XIXQ@135619|Oceanospirillales 135619|Oceanospirillales G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_9849_1 765912.Thimo_3702 1.77e-56 194.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_18232_1 425104.Ssed_2151 7.48e-29 107.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria,2QEDX@267890|Shewanellaceae 1236|Gammaproteobacteria S DoxX yqjF - - ko:K15977 - - - - ko00000 - - - DoxX k141_18232_2 95619.PM1_0218905 5.98e-24 97.8 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator IV02_08490 - - - - - - - - - - - HTH_1,LysR_substrate k141_17508_1 1278309.KB907100_gene1949 3.99e-225 658.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIUY@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR,TPP_enzyme_C k141_17508_2 207954.MED92_01474 6.67e-123 358.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1XH9Y@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_18934_1 368407.Memar_2430 5.71e-11 63.9 COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,2N9CG@224756|Methanomicrobia 2157|Archaea O Belongs to the peptidase S16 family - - - - - - - - - - - - - k141_18934_2 493475.GARC_2070 1.83e-41 139.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Belongs to the BolA IbaG family bolA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_5715_1 1026882.MAMP_01292 6.4e-85 258.0 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales 72273|Thiotrichales S Peptidase M50 - - - - - - - - - - - - Peptidase_M50 k141_4281_1 713586.KB900536_gene929 1.63e-60 212.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales 135613|Chromatiales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_79_1 1218352.B597_004930 9.51e-56 189.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1Z1U9@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_12656_1 582744.Msip34_0960 3.06e-19 89.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KKBA@206350|Nitrosomonadales 206350|Nitrosomonadales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_17509_1 1208323.B30_02290 1.28e-87 270.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TTE1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_804_1 317025.Tcr_1800 2.62e-97 292.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_8474_1 1288826.MSNKSG1_13017 0.0 1196.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,464U2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_2183_1 1278309.KB907099_gene2977 8.34e-102 295.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,1XJQI@135619|Oceanospirillales 135619|Oceanospirillales S nuclease - - - - - - - - - - - - NYN k141_20355_1 62977.ACIAD1936 3.6e-08 57.4 COG4313@1|root,COG4313@2|Bacteria,1R58D@1224|Proteobacteria,1RYZE@1236|Gammaproteobacteria,3NM9G@468|Moraxellaceae 1236|Gammaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_6370_1 861299.J421_0766 1.59e-84 270.0 COG5001@1|root,COG5001@2|Bacteria,1ZT12@142182|Gemmatimonadetes 142182|Gemmatimonadetes T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS k141_6370_2 118173.KB235914_gene3296 3.89e-122 370.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,1H8S9@1150|Oscillatoriales 1117|Cyanobacteria IQ Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II,adh_short,adh_short_C2 k141_1489_1 1288826.MSNKSG1_02198 0.0 1055.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,464FJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) liuB - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_1489_2 1288826.MSNKSG1_02193 1.01e-184 514.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,465S5@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase liuC - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_4282_1 765914.ThisiDRAFT_1728 4.32e-62 199.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_17510_1 1443111.JASG01000004_gene2692 9e-91 288.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,3ZWAZ@60136|Sulfitobacter 28211|Alphaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim k141_4963_1 1288826.MSNKSG1_12522 2.81e-78 236.0 COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,467KT@72275|Alteromonadaceae 1236|Gammaproteobacteria J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 k141_4963_2 1288826.MSNKSG1_12527 5.75e-187 526.0 COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,1RPY9@1236|Gammaproteobacteria,46CHM@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_4963_3 1288826.MSNKSG1_12532 4.56e-152 426.0 COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,4666H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 k141_4963_4 1288826.MSNKSG1_12537 1.17e-51 168.0 COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,1S64F@1236|Gammaproteobacteria,467WH@72275|Alteromonadaceae 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_7071_1 1278309.KB907102_gene187 5.87e-192 537.0 COG2358@1|root,COG2358@2|Bacteria,1NSTZ@1224|Proteobacteria,1RP8B@1236|Gammaproteobacteria,1XHFZ@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter substrate-binding protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_7071_2 1278309.KB907102_gene188 3.64e-104 321.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XH5B@135619|Oceanospirillales 135619|Oceanospirillales S permease - - - - - - - - - - - - DctM k141_4283_1 298386.PBPRB0651 5.77e-89 266.0 COG2010@1|root,COG2010@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_17511_1 1094715.CM001373_gene2170 7.51e-70 218.0 COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,1S2QF@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_14057_2 626887.J057_14500 7.31e-48 157.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,466Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_5717_1 1288826.MSNKSG1_13462 2.04e-132 387.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,464KD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_2889_1 1212548.B381_14226 7.86e-43 146.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1Z20I@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k141_2889_2 765913.ThidrDRAFT_1979 3.31e-109 327.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid potE - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k141_4284_2 935557.ATYB01000009_gene768 4.17e-09 60.5 COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,2TV5V@28211|Alphaproteobacteria,4B8UX@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,dCache_1 k141_21072_1 1297570.MESS4_830012 3.93e-09 59.3 28MT5@1|root,2ZB1G@2|Bacteria,1RC18@1224|Proteobacteria,2U40K@28211|Alphaproteobacteria,43KV5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_21072_2 314345.SPV1_03043 1.31e-35 132.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria 1224|Proteobacteria G Belongs to the glucose-6-phosphate 1-epimerase family yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_18234_1 1255043.TVNIR_3262 8.58e-115 359.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales 135613|Chromatiales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_16120_1 1278309.KB907099_gene2746 8.31e-99 305.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XICX@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_16120_2 1278309.KB907099_gene2745 1.57e-296 810.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1XIDY@135619|Oceanospirillales 135619|Oceanospirillales E branched-chain amino acid - - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 k141_14764_1 1158760.AQXP01000023_gene2345 1.28e-31 125.0 COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria,1WW42@135613|Chromatiales 135613|Chromatiales IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_3604_1 1278309.KB907099_gene2755 1.71e-47 157.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,1XK0Y@135619|Oceanospirillales 135619|Oceanospirillales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_3604_2 1278309.KB907099_gene2756 7.42e-39 135.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,1XIDZ@135619|Oceanospirillales 135619|Oceanospirillales KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW k141_10565_1 557599.MKAN_15275 1.13e-50 171.0 COG0778@1|root,COG0778@2|Bacteria 2|Bacteria C coenzyme F420-1:gamma-L-glutamate ligase activity - - - - - - - - - - - - Nitroreductase k141_10565_2 1168067.JAGP01000001_gene1282 1.07e-16 75.5 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,1SDWW@1236|Gammaproteobacteria,462MF@72273|Thiotrichales 72273|Thiotrichales K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_8475_1 700598.Niako_2446 1.45e-12 73.9 COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1INYN@117747|Sphingobacteriia 976|Bacteroidetes P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family czcA - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran k141_17513_1 1479237.JMLY01000001_gene1525 7.22e-29 118.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_5718_1 393595.ABO_2567 1.68e-71 221.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XH6V@135619|Oceanospirillales 135619|Oceanospirillales D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_5718_2 326297.Sama_3468 2.69e-06 48.5 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,2QAA0@267890|Shewanellaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_4964_1 1163407.UU7_03427 1.85e-22 91.7 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1X6G2@135614|Xanthomonadales 135614|Xanthomonadales I Oligoketide cyclase - - - - - - - - - - - - Polyketide_cyc k141_4964_2 713586.KB900536_gene3024 1.17e-31 114.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WZ6P@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0125 (RnfH) family - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_4964_3 1122604.JONR01000014_gene248 6.32e-26 102.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1X6JC@135614|Xanthomonadales 135614|Xanthomonadales J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA k141_4964_4 187272.Mlg_1905 1.76e-43 144.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1WYAR@135613|Chromatiales 135613|Chromatiales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_805_1 1121479.AUBS01000003_gene4158 1.22e-227 642.0 COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade - 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 k141_14059_1 1158150.KB906243_gene1650 4.91e-55 192.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_11970_1 1288826.MSNKSG1_15891 1.04e-201 571.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,46428@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG2202 FOG PAS PAC domain aer-1 - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_6371_2 883126.HMPREF9710_03302 1.66e-27 108.0 COG0745@1|root,COG0745@2|Bacteria,1QWG0@1224|Proteobacteria,2WGYI@28216|Betaproteobacteria,474FD@75682|Oxalobacteraceae 28216|Betaproteobacteria KT Helix-turn-helix domain - - - - - - - - - - - - HTH_17,Response_reg k141_2890_1 876044.IMCC3088_942 2.3e-40 139.0 COG1942@1|root,COG1942@2|Bacteria,1N5SA@1224|Proteobacteria,1SQ36@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein 4-oxalocrotonate tautomerase homolog - - - - - - - - - - - - Tautomerase k141_2890_2 85643.Tmz1t_3094 2.16e-37 129.0 COG1018@1|root,COG1018@2|Bacteria,1NA1K@1224|Proteobacteria,2VUWC@28216|Betaproteobacteria,2KXFE@206389|Rhodocyclales 206389|Rhodocyclales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2 k141_9155_1 744980.TRICHSKD4_5672 5.36e-58 191.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k141_9155_2 1122214.AQWH01000003_gene4087 7.24e-131 395.0 COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2PKB0@255475|Aurantimonadaceae 28211|Alphaproteobacteria P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,BPD_transp_1,OppC_N,oligo_HPY k141_11300_1 1278309.KB907101_gene494 8.86e-206 593.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,1XIKP@135619|Oceanospirillales 135619|Oceanospirillales E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 k141_9850_1 1123277.KB893217_gene4595 2.39e-11 70.5 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_12657_1 1461693.ATO10_00770 1.26e-33 143.0 COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U9Q1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S low-complexity proteins - - - - - - - - - - - - Pentapeptide k141_81_2 765910.MARPU_03775 1.71e-47 154.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales 135613|Chromatiales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_81_4 715451.ambt_16495 5.21e-38 129.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,467RN@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_81_5 298386.PBPRA0328 8.92e-18 76.3 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XYAY@135623|Vibrionales 135623|Vibrionales J Belongs to the universal ribosomal protein uL29 family rpmC GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_2185_1 1122614.JHZF01000015_gene2504 9.06e-116 355.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,2PDMP@252301|Oceanicola 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_16838_1 1288826.MSNKSG1_02509 0.0 941.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_16838_2 1288826.MSNKSG1_02504 1.76e-79 235.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,467GP@72275|Alteromonadaceae 1236|Gammaproteobacteria C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_9 k141_16838_3 1288826.MSNKSG1_02499 9.4e-138 390.0 COG1280@1|root,COG1280@2|Bacteria,1RF1D@1224|Proteobacteria,1S43Q@1236|Gammaproteobacteria,467BF@72275|Alteromonadaceae 1236|Gammaproteobacteria E Lysine exporter protein (LysE YggA) - - - - - - - - - - - - LysE k141_16838_4 1288826.MSNKSG1_02494 1.1e-233 644.0 COG1020@1|root,COG1020@2|Bacteria,1QXFM@1224|Proteobacteria,1T3AN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q D-alanine [D-alanyl carrier protein] ligase activity - - - - - - - - - - - - - k141_16838_5 1288826.MSNKSG1_02489 1.01e-224 619.0 COG1307@1|root,COG1307@2|Bacteria,1R5M9@1224|Proteobacteria,1RZYN@1236|Gammaproteobacteria,46813@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV k141_16838_6 1288826.MSNKSG1_02484 2.98e-211 582.0 COG3687@1|root,COG3687@2|Bacteria,1RBP4@1224|Proteobacteria,1S33P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metal-dependent hydrolase - - - ko:K07044 - - - - ko00000 - - - Metal_hydrol k141_8625_1 1278309.KB907102_gene155 8.15e-44 147.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,1XKA5@135619|Oceanospirillales 135619|Oceanospirillales S Yip1 domain - - - - - - - - - - - - DUF1282 k141_8625_2 626887.J057_12891 2.11e-108 318.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria,465HQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M aspartate racemase ygeA GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_8625_3 1278309.KB907102_gene157 3.6e-165 468.0 COG2199@1|root,COG3706@2|Bacteria,1QVPY@1224|Proteobacteria,1T2GE@1236|Gammaproteobacteria,1XKWV@135619|Oceanospirillales 135619|Oceanospirillales T Chemoreceptor zinc-binding domain - - 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - CZB,GGDEF k141_19762_1 1123360.thalar_03141 7.73e-102 306.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria MA20_36195 - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_19762_2 52598.EE36_08308 1.15e-48 156.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,3ZXNC@60136|Sulfitobacter 28211|Alphaproteobacteria H Pterin 4 alpha carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_2313_1 1278309.KB907102_gene70 1.72e-44 155.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1XJJQ@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_2313_2 1278309.KB907102_gene69 3.77e-22 92.8 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XHNJ@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_7961_1 279383.Q5DNA0_9CAUD 1.87e-23 104.0 4QB9T@10239|Viruses,4R0FI@35237|dsDNA viruses no RNA stage,4QQR9@28883|Caudovirales,4QN2W@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_7961_2 1353537.TP2_06930 0.000286 45.4 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2XKK3@285107|Thioclava 28211|Alphaproteobacteria O Belongs to the peptidase S1C family degPch1 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_19113_1 1121943.KB900003_gene2819 6.71e-05 44.7 2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,1SGHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K06950 - - - - ko00000 - - - - k141_19113_2 765913.ThidrDRAFT_1028 3.84e-34 135.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 k141_12808_1 177439.DP0024 8.48e-25 98.2 COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria,2MM3T@213118|Desulfobacterales 28221|Deltaproteobacteria P PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_3 k141_8626_1 1443113.LC20_03373 6.83e-26 107.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,41ECQ@629|Yersinia 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans k141_12127_1 1121373.KB903640_gene3749 3.58e-45 155.0 COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47K8M@768503|Cytophagia 976|Bacteroidetes O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase fklB - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_6482_1 1288826.MSNKSG1_08143 0.0 1531.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_6482_2 1288826.MSNKSG1_08148 1.02e-206 573.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,464XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_6482_3 1288826.MSNKSG1_08153 6.48e-216 597.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,466HG@72275|Alteromonadaceae 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_6482_4 1288826.MSNKSG1_08158 1.45e-106 307.0 2C5QF@1|root,331W9@2|Bacteria,1N7AE@1224|Proteobacteria,1SCH2@1236|Gammaproteobacteria,468CH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 k141_4482_1 1288826.MSNKSG1_15372 1.09e-176 518.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,464RK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECs_1301.ECs3167,iG2583_1286.G2583_2820,iZ_1308.Z3542 Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_7231_1 367336.OM2255_09991 2.21e-68 215.0 COG1879@1|root,COG1879@2|Bacteria,1MWGU@1224|Proteobacteria,2U2E3@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC-type sugar transport system periplasmic component mocBch2 - - ko:K10439,ko:K17213 ko02010,ko02030,map02010,map02030 M00212,M00593 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_7231_2 314232.SKA53_02276 2.09e-52 173.0 COG4130@1|root,COG4130@2|Bacteria,1PC6C@1224|Proteobacteria,2TUIJ@28211|Alphaproteobacteria,2P9WH@245186|Loktanella 28211|Alphaproteobacteria G Xylose isomerase-like TIM barrel iolI - 5.3.99.11 ko:K06606 ko00562,ko01120,map00562,map01120 - R09952 RC01513 ko00000,ko00001,ko01000 - - - AP_endonuc_2 k141_17704_2 1300345.LF41_2005 3.85e-26 108.0 COG0739@1|root,COG0739@2|Bacteria,1RIS0@1224|Proteobacteria,1S6KP@1236|Gammaproteobacteria,1X5YN@135614|Xanthomonadales 135614|Xanthomonadales M Peptidase family M23 - - - - - - - - - - - - DUF4124,Peptidase_M23 k141_2314_2 105559.Nwat_0492 2.88e-37 136.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1WW5X@135613|Chromatiales 135613|Chromatiales J Elongation factor P--(R)-beta-lysine ligase - - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_21220_1 384676.PSEEN5295 6.74e-14 71.2 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Required for the activity of the bacterial periplasmic transport system of putrescine potF1 - - ko:K02055,ko:K11073 ko02010,ko02024,map02010,map02024 M00193,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11,3.A.1.11.2 - - SBP_bac_8 k141_12809_1 1278309.KB907104_gene835 1.33e-118 370.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XI32@135619|Oceanospirillales 135619|Oceanospirillales N ImcF-related N-terminal domain - - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N,OmpA k141_18389_1 439496.RBY4I_3696 1.42e-79 251.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2TR3Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 k141_16251_1 398527.Bphyt_2376 5.25e-59 201.0 COG2207@1|root,COG2207@2|Bacteria,1R5XR@1224|Proteobacteria,2WEM7@28216|Betaproteobacteria,1KH0T@119060|Burkholderiaceae 28216|Betaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_16990_1 1127673.GLIP_1517 2.2e-80 253.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_20524_1 472759.Nhal_2213 3.77e-115 364.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales 135613|Chromatiales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_11434_1 1288826.MSNKSG1_04186 6.49e-230 658.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_11434_2 1288826.MSNKSG1_04181 6.4e-109 320.0 COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,467YG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0036094,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_3755_1 1288826.MSNKSG1_16241 6.48e-258 711.0 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,467MC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase regB - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_3755_2 1288826.MSNKSG1_16236 2.31e-120 344.0 COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,1S3PE@1236|Gammaproteobacteria,467FX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain regA - - ko:K15012 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg k141_3755_3 1288826.MSNKSG1_16231 0.0 905.0 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,46A57@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CZB,EAL,GAF_2,GGDEF,Hemerythrin,PAS_4,PAS_9,Protoglobin k141_17705_1 1121943.KB899989_gene3361 7.79e-48 168.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1XI7X@135619|Oceanospirillales 135619|Oceanospirillales C COG0348 Polyferredoxin - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_7962_2 1163617.SCD_n02602 3.22e-108 335.0 COG2203@1|root,COG3437@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3850@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria 28216|Betaproteobacteria T metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - DUF3369,HD,HD_5,Response_reg k141_951_1 1278309.KB907105_gene1464 3.89e-182 534.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XJ1N@135619|Oceanospirillales 135619|Oceanospirillales Q Paraquat-inducible protein B - - - - - - - - - - - - MlaD k141_951_2 1278309.KB907105_gene1463 1.92e-105 310.0 28JUM@1|root,2Z9JN@2|Bacteria,1NDV6@1224|Proteobacteria,1S3HC@1236|Gammaproteobacteria,1XJNH@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_951_3 1278309.KB907105_gene1462 2.74e-117 339.0 28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1XJBR@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2959) - - - - - - - - - - - - DUF2959 k141_951_4 1278309.KB907105_gene1461 7.81e-118 344.0 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,1XHZP@135619|Oceanospirillales 135619|Oceanospirillales S COG4240 Predicted kinase - - 2.7.1.31 ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ArgK,PRK k141_2315_2 1122604.JONR01000001_gene1921 7.36e-76 234.0 COG0500@1|root,COG0500@2|Bacteria,1QWS3@1224|Proteobacteria,1T4VS@1236|Gammaproteobacteria,1X6GY@135614|Xanthomonadales 135614|Xanthomonadales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_31 k141_8627_1 1123508.JH636452_gene6925 1.83e-44 163.0 COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2J2DQ@203682|Planctomycetes 203682|Planctomycetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,dCache_1 k141_8627_2 292415.Tbd_1192 9.1e-62 192.0 COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria,1KT24@119069|Hydrogenophilales 119069|Hydrogenophilales T cheY-homologous receiver domain - - - ko:K02485 - - - - ko00000,ko02022 - - - Response_reg k141_5122_1 1232683.ADIMK_1457 1.37e-68 216.0 COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,1S34B@1236|Gammaproteobacteria,46710@72275|Alteromonadaceae 1236|Gammaproteobacteria GM Capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - k141_5122_2 1278309.KB907102_gene28 1.21e-29 115.0 2EPGI@1|root,33H34@2|Bacteria,1NJDY@1224|Proteobacteria,1SIB4@1236|Gammaproteobacteria,1XPUP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_251_1 1288826.MSNKSG1_09098 0.0 953.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,465ES@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_251_2 1288826.MSNKSG1_09093 0.0 912.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,465AG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_251_3 1288826.MSNKSG1_09088 1.14e-56 176.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,467YW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_19115_2 1049564.TevJSym_an00330 5.02e-31 115.0 2AAM4@1|root,30ZYM@2|Bacteria,1RFTG@1224|Proteobacteria,1S4UQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF2384 k141_12810_1 754476.Q7A_2823 6.54e-123 362.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales 72273|Thiotrichales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_9283_1 1288826.MSNKSG1_08553 1.03e-106 325.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,4658F@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG1450 Type II secretory pathway, component PulD gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - SPOR,Secretin,Secretin_N k141_9283_2 1288826.MSNKSG1_08548 0.0 1242.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_9283_3 1288826.MSNKSG1_08543 5.3e-128 365.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,464MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_9283_4 1288826.MSNKSG1_08538 6.12e-133 395.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase bifA - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_3 k141_5856_3 1288826.MSNKSG1_15961 0.0 1120.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_5856_4 1288826.MSNKSG1_15966 1.55e-130 375.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,4651J@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_3086_1 1288826.MSNKSG1_15397 2.27e-245 686.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,469GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Proton_antipo_M,Proton_antipo_N k141_3086_2 1288826.MSNKSG1_15392 4.84e-59 183.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,468MA@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_3086_3 1288826.MSNKSG1_15387 4.32e-109 315.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,46ARW@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J) nuoJ GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2280,iAF1260.b2280,iAPECO1_1312.APECO1_4285,iB21_1397.B21_02165,iBWG_1329.BWG_2054,iE2348C_1286.E2348C_2420,iEC042_1314.EC042_2521,iEC55989_1330.EC55989_2524,iECABU_c1320.ECABU_c26120,iECBD_1354.ECBD_1381,iECB_1328.ECB_02205,iECDH10B_1368.ECDH10B_2442,iECDH1ME8569_1439.ECDH1ME8569_2217,iECD_1391.ECD_02205,iECED1_1282.ECED1_2744,iECH74115_1262.ECH74115_3419,iECIAI1_1343.ECIAI1_2354,iECIAI39_1322.ECIAI39_2427,iECNA114_1301.ECNA114_2370,iECO103_1326.ECO103_2744,iECO111_1330.ECO111_3028,iECO26_1355.ECO26_3268,iECOK1_1307.ECOK1_2513,iECP_1309.ECP_2319,iECS88_1305.ECS88_2427,iECSE_1348.ECSE_2537,iECSF_1327.ECSF_2157,iECSP_1301.ECSP_3154,iECUMN_1333.ECUMN_2619,iECW_1372.ECW_m2468,iECs_1301.ECs3164,iEKO11_1354.EKO11_1487,iETEC_1333.ETEC_2415,iEcDH1_1363.EcDH1_1377,iEcE24377_1341.EcE24377A_2573,iEcHS_1320.EcHS_A2429,iEcSMS35_1347.EcSMS35_2434,iEcolC_1368.EcolC_1372,iJO1366.b2280,iJR904.b2280,iLF82_1304.LF82_1547,iNRG857_1313.NRG857_11545,iSBO_1134.SBO_2313,iSDY_1059.SDY_2476,iSFV_1184.SFV_2347,iSF_1195.SF2356,iSFxv_1172.SFxv_2600,iSSON_1240.SSON_2337,iS_1188.S2491,iSbBS512_1146.SbBS512_E2656,iUMN146_1321.UM146_05415,iUMNK88_1353.UMNK88_2830,iUTI89_1310.UTI89_C2560,iWFL_1372.ECW_m2468,iY75_1357.Y75_RS11955,iZ_1308.Z3539,ic_1306.c2821 Oxidored_q3 k141_3086_4 1288826.MSNKSG1_15382 3.22e-126 360.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,466PB@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2281,iAF1260.b2281,iAPECO1_1312.APECO1_4284,iB21_1397.B21_02166,iBWG_1329.BWG_2055,iE2348C_1286.E2348C_2421,iEC042_1314.EC042_2522,iEC55989_1330.EC55989_2525,iECABU_c1320.ECABU_c26130,iECBD_1354.ECBD_1380,iECB_1328.ECB_02206,iECDH10B_1368.ECDH10B_2443,iECDH1ME8569_1439.ECDH1ME8569_2218,iECD_1391.ECD_02206,iECED1_1282.ECED1_2745,iECH74115_1262.ECH74115_3420,iECIAI1_1343.ECIAI1_2355,iECIAI39_1322.ECIAI39_2428,iECNA114_1301.ECNA114_2371,iECO103_1326.ECO103_2745,iECO111_1330.ECO111_3029,iECO26_1355.ECO26_3269,iECOK1_1307.ECOK1_2514,iECP_1309.ECP_2320,iECS88_1305.ECS88_2428,iECSE_1348.ECSE_2538,iECSF_1327.ECSF_2158,iECSP_1301.ECSP_3155,iECUMN_1333.ECUMN_2620,iECW_1372.ECW_m2469,iECs_1301.ECs3165,iEKO11_1354.EKO11_1486,iETEC_1333.ETEC_2416,iEcDH1_1363.EcDH1_1376,iEcE24377_1341.EcE24377A_2574,iEcHS_1320.EcHS_A2430,iEcSMS35_1347.EcSMS35_2435,iEcolC_1368.EcolC_1371,iG2583_1286.G2583_2818,iJO1366.b2281,iJR904.b2281,iLF82_1304.LF82_1546,iNRG857_1313.NRG857_11550,iPC815.YPO2548,iSBO_1134.SBO_2314,iSFV_1184.SFV_2348,iSF_1195.SF2357,iSFxv_1172.SFxv_2601,iS_1188.S2492,iSbBS512_1146.SbBS512_E2657,iUMN146_1321.UM146_05410,iUMNK88_1353.UMNK88_2831,iUTI89_1310.UTI89_C2561,iWFL_1372.ECW_m2469,iY75_1357.Y75_RS11960,iZ_1308.Z3540,ic_1306.c2822 Fer4 k141_3086_5 1288826.MSNKSG1_15377 5.07e-234 644.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,4643U@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_3086_6 1288826.MSNKSG1_15372 1.38e-177 520.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,464RK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECs_1301.ECs3167,iG2583_1286.G2583_2820,iZ_1308.Z3542 Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_12833_1 1123368.AUIS01000018_gene719 6.19e-76 252.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RRFG@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Cache_2 - - - - - - - - - - - - EAL,GGDEF,dCache_2 k141_6505_1 713586.KB900536_gene1841 5.16e-109 350.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_15618_1 1122207.MUS1_04520 3.17e-105 308.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,1XIDZ@135619|Oceanospirillales 135619|Oceanospirillales KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW k141_15618_2 232346.JHQL01000002_gene1076 1.05e-07 53.1 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,1XK0Y@135619|Oceanospirillales 135619|Oceanospirillales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_17725_1 392500.Swoo_0491 2.8e-24 110.0 COG1520@1|root,COG2304@1|root,COG2911@1|root,COG2931@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,2QESR@267890|Shewanellaceae 1236|Gammaproteobacteria Q PFAM Hemolysin-type calcium-binding region lapA - - ko:K12549 - - - - ko00000 - - - Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VWA,VWA_2 k141_19786_1 1288826.MSNKSG1_17945 4.16e-41 144.0 COG0457@1|root,COG0457@2|Bacteria,1N8YE@1224|Proteobacteria,1RTI2@1236|Gammaproteobacteria,4699R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - ko:K12284 - - - - ko00000,ko02044 - - - TPR_16 k141_19786_2 1288826.MSNKSG1_17950 2.94e-59 197.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,46485@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N k141_11446_1 313612.L8106_23595 1.1e-34 124.0 COG0235@1|root,COG0235@2|Bacteria,1G59N@1117|Cyanobacteria,1HANS@1150|Oscillatoriales 1117|Cyanobacteria G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II k141_11446_2 926550.CLDAP_08980 4.49e-109 324.0 COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_14214_1 1123487.KB892850_gene305 5.45e-23 97.1 2CPPK@1|root,32SJJ@2|Bacteria,1MZQ2@1224|Proteobacteria,2VU8G@28216|Betaproteobacteria,2KZ8N@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 k141_16997_1 1123393.KB891328_gene597 6.99e-13 74.3 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria 1224|Proteobacteria S protein (some members contain a von Willebrand factor type A (vWA) domain IV02_10730 - - - - - - - - - - - DUF58 k141_2337_2 207954.MED92_09666 4.42e-82 248.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XJND@135619|Oceanospirillales 135619|Oceanospirillales D Maf-like protein maf-2 - - - - - - - - - - - Maf k141_2337_3 379731.PST_4047 1.36e-56 195.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z12X@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NT Aerotaxis receptor Aer aer - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_7985_1 472759.Nhal_1052 5.8e-81 246.0 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1WXZH@135613|Chromatiales 135613|Chromatiales G PFAM Phosphoglycerate mutase - - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_7985_2 1165841.SULAR_02083 7.65e-64 202.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,42SS7@68525|delta/epsilon subdivisions 1224|Proteobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_13512_1 573569.F7308_0965 1.26e-93 278.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,460VQ@72273|Thiotrichales 72273|Thiotrichales S PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_13512_2 876269.ARWA01000001_gene1947 2.4e-23 94.7 COG2149@1|root,COG2149@2|Bacteria,1N7T3@1224|Proteobacteria,2UG6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_1702_1 388399.SSE37_18467 8.89e-62 191.0 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the Nudix hydrolase family mutT GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - Acetyltransf_3,NUDIX,NUDIX_4 k141_1702_2 467661.RKLH11_749 3.61e-70 223.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,3ZGX2@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_21898_1 1095769.CAHF01000022_gene432 1.32e-56 204.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_9994_1 765913.ThidrDRAFT_1581 1.17e-14 80.5 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXQS@135613|Chromatiales 135613|Chromatiales T Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_4,PAS_9 k141_16274_1 28229.ND2E_4292 1.57e-70 243.0 COG0784@1|root,COG2202@1|root,COG2703@1|root,COG3829@1|root,COG3852@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2703@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,1NC9X@1224|Proteobacteria,1T242@1236|Gammaproteobacteria 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_9308_1 1121918.ARWE01000001_gene3354 8.88e-111 342.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2WTI2@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Domain of unknown function (DUF1974) - - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_15619_1 765912.Thimo_1292 2.08e-17 81.3 COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1WWV8@135613|Chromatiales 135613|Chromatiales L DNA polymerase III - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_15619_2 351016.RAZWK3B_14673 1.51e-12 67.8 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2TRZC@28211|Alphaproteobacteria,2P1AD@2433|Roseobacter 28211|Alphaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_5237_1 1550073.JROH01000016_gene356 1.17e-35 132.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,2K1VS@204457|Sphingomonadales 204457|Sphingomonadales E Aminomethyltransferase folate-binding domain - - - ko:K15064 ko00627,ko01120,map00627,map01120 - R09270 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C k141_1782_1 700598.Niako_2343 1.7e-15 78.6 COG2890@1|root,COG2890@2|Bacteria,4P40V@976|Bacteroidetes 976|Bacteroidetes J protein-(glutamine-N5) methyltransferase activity - - - - - - - - - - - - - k141_16358_1 373994.Riv7116_1797 2.01e-77 246.0 COG3667@1|root,COG3667@2|Bacteria,1G2HW@1117|Cyanobacteria 1117|Cyanobacteria P PFAM copper resistance B precursor - - - ko:K07233 - - - - ko00000 - - - CopB k141_16358_2 1415754.JQMK01000012_gene708 1.44e-192 555.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases copA2 - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_12245_1 1122212.AULO01000006_gene1711 5.4e-47 162.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1XJCT@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin domain-containing protein trx-1 - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_19867_1 335543.Sfum_4042 5.96e-110 327.0 COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,42MRB@68525|delta/epsilon subdivisions,2WIZD@28221|Deltaproteobacteria,2MQTF@213462|Syntrophobacterales 28221|Deltaproteobacteria C PFAM nitrite and sulphite reductase 4Fe-4S dsrA - 1.8.99.5 ko:K11180 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_14986_1 367336.OM2255_11005 2.71e-78 246.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_10850_1 717773.Thicy_0297 1.92e-90 280.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,46029@72273|Thiotrichales 72273|Thiotrichales C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18470_1 936155.HFELIS_08600 0.000259 49.3 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C Glycerol-3-phosphate dehydrogenase glpC - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_17,Fer4_7,Fer4_8 k141_20619_1 887062.HGR_02039 1.93e-117 361.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria,4AB5W@80864|Comamonadaceae 28216|Betaproteobacteria P TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_8717_1 589873.EP13_07045 1.23e-85 263.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_8717_2 713586.KB900536_gene2249 2.95e-32 118.0 2E1SU@1|root,32X2N@2|Bacteria,1N4HW@1224|Proteobacteria,1SAEX@1236|Gammaproteobacteria,1X167@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8717_3 1380600.AUYN01000006_gene551 0.000176 48.1 COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia 976|Bacteroidetes S amidophosphoribosyl-transferase comF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Pribosyltran k141_11527_1 400668.Mmwyl1_3389 8.81e-145 415.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1XH6J@135619|Oceanospirillales 135619|Oceanospirillales E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.9 ko:K00611,ko:K09065 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_11527_2 870187.Thini_1825 1.94e-74 235.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,4607E@72273|Thiotrichales 72273|Thiotrichales E PFAM aminotransferase class-III argD - 2.6.1.11,2.6.1.13,2.6.1.17 ko:K00819,ko:K00821 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_13612_1 1569209.BBPH01000163_gene1055 1.65e-77 244.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,2PVNU@265|Paracoccus 28211|Alphaproteobacteria C IG-like fold at C-terminal of FixG, putative oxidoreductase ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_1783_1 391625.PPSIR1_33881 3.24e-36 132.0 COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria,42YBC@68525|delta/epsilon subdivisions,2WUEA@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q methyltransferase - - - - - - - - - - - - - k141_10851_1 713586.KB900536_gene81 2.8e-81 256.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1WWI5@135613|Chromatiales 135613|Chromatiales H Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - - - - - - - - - - HemN_C,Radical_SAM k141_5265_1 754476.Q7A_1687 9.16e-77 238.0 COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,460D9@72273|Thiotrichales 72273|Thiotrichales Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_5265_2 90813.JQMT01000001_gene1960 4.13e-05 45.1 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462B1@72273|Thiotrichales 72273|Thiotrichales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_1098_1 765914.ThisiDRAFT_2568 4.9e-23 94.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1WYGU@135613|Chromatiales 135613|Chromatiales N flagellar protein FliS - - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_17825_1 326426.Bbr_1683 1.84e-30 115.0 COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CZTX@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal regX3 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - ko:K07776 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_18490_2 316067.Geob_2748 1.99e-35 125.0 2E3G3@1|root,32YEY@2|Bacteria,1N87D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_15005_1 1238190.AMQY01000014_gene1007 4.94e-08 53.5 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1XH47@135619|Oceanospirillales 135619|Oceanospirillales IQ reductase - - - - - - - - - - - - adh_short k141_15005_2 765913.ThidrDRAFT_0898 9.43e-44 153.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1WX5T@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_5266_1 339670.Bamb_2817 2.09e-24 101.0 COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,2VIG8@28216|Betaproteobacteria,1K0WC@119060|Burkholderiaceae 28216|Betaproteobacteria G polysaccharide deacetylase - - 3.5.1.41 ko:K01452 ko00520,ko01100,map00520,map01100 - R02333 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Polysacc_deac_1 k141_2465_1 196367.JNFG01000020_gene4805 8.67e-95 291.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1JZV1@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.96 ko:K16871 ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120 M00027 R10178 RC00008,RC00062 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_3 k141_1099_1 298386.PBPRB0649 4.54e-47 157.0 COG1143@1|root,COG1245@1|root,COG1143@2|Bacteria,COG1245@2|Bacteria,1QW0T@1224|Proteobacteria,1T38G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Ferredoxin-type protein napG of Proteobacteria UniRef RepID napG - - ko:K02573 - - - - ko00000 - - - Fer4,Fer4_4,Fer4_7 k141_19252_1 926561.KB900618_gene321 8.14e-58 193.0 COG0701@1|root,COG0701@2|Bacteria,1VQXZ@1239|Firmicutes 1239|Firmicutes S Predicted permease - - - - - - - - - - - - ArsP_1 k141_12962_1 1121440.AUMA01000005_gene2646 3.86e-33 143.0 COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,42SMY@68525|delta/epsilon subdivisions,2WPKE@28221|Deltaproteobacteria,2MAJJ@213115|Desulfovibrionales 28221|Deltaproteobacteria T ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_3,PAS_9,Response_reg k141_399_1 472759.Nhal_2781 4.34e-102 303.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_4587_1 290512.Paes_0936 3.05e-16 81.3 COG0671@1|root,COG0671@2|Bacteria,1FDVG@1090|Chlorobi 1090|Chlorobi I PFAM phosphoesterase, PA-phosphatase related - - - - - - - - - - - - PAP2 k141_4587_2 1121439.dsat_0262 3.4e-06 49.3 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2M8YN@213115|Desulfovibrionales 28221|Deltaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_5267_1 1288826.MSNKSG1_02123 1.81e-69 214.0 COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,1S3DM@1236|Gammaproteobacteria,467DG@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_5267_2 1288826.MSNKSG1_02118 1.25e-30 115.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,469G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235,PilZ k141_12265_1 1255043.TVNIR_3001 3.16e-94 286.0 2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria,1SBQY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11541_1 323261.Noc_2461 3.56e-109 332.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales 135613|Chromatiales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_17826_1 1288826.MSNKSG1_02118 3.72e-207 574.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,469G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235,PilZ k141_2466_1 1288826.MSNKSG1_08793 2.68e-71 223.0 COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria,4668D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chain length determinant protein wzz - - - - - - - - - - - GNVR,Wzz k141_2466_2 1288826.MSNKSG1_08788 7.02e-17 77.8 COG3765@1|root,COG3765@2|Bacteria,1N2QS@1224|Proteobacteria,1SAAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Chain length determinant protein - - - - - - - - - - - - Wzz k141_3852_1 1288826.MSNKSG1_02243 3.91e-97 297.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,464TT@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_3852_2 1288826.MSNKSG1_02253 2.15e-239 660.0 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,466WD@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_3852_3 1288826.MSNKSG1_02258 1.39e-119 370.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_6616_1 1278309.KB907099_gene2414 1.8e-133 387.0 COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,1XJUQ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_6616_2 1278309.KB907099_gene2415 2.42e-27 102.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XJQQ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 k141_1100_1 472759.Nhal_0886 1.97e-98 300.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_1100_2 323261.Noc_1198 6.45e-16 74.3 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales 135613|Chromatiales O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB k141_16379_1 472759.Nhal_2462 1.57e-70 216.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,1WWV2@135613|Chromatiales 135613|Chromatiales I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_16379_2 1304883.KI912532_gene2596 3.73e-88 269.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales 206389|Rhodocyclales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_16379_3 398767.Glov_0767 1.85e-47 167.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,43SZS@69541|Desulfuromonadales 28221|Deltaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_18491_1 1278309.KB907100_gene2055 1.85e-65 203.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XKTT@135619|Oceanospirillales 135619|Oceanospirillales S Integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_18491_2 1278309.KB907100_gene2054 4.59e-80 244.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1XI4M@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_14287_1 697282.Mettu_1866 1.52e-58 202.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XF9A@135618|Methylococcales 135618|Methylococcales M Transglycosylase SLT domain - - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_21325_2 1423814.HMPREF0549_1640 6.13e-07 51.6 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin k141_21325_3 1122194.AUHU01000005_gene984 7.17e-86 264.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,466A4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015889,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0031419,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - ko:K02016,ko:K06858 ko02010,map02010 M00240,M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13,3.A.1.14 - iECH74115_1262.ECH74115_0168,iECSP_1301.ECSP_0159,iECs_1301.ECs0162,iZ_1308.Z0169 Peripla_BP_2 k141_15007_1 1198232.CYCME_1365 1.63e-35 135.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4609S@72273|Thiotrichales 72273|Thiotrichales Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_1101_1 935261.JAGL01000025_gene50 4.14e-24 96.7 COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,2TV1A@28211|Alphaproteobacteria,43HBV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F thymidine kinase tdk - 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK k141_1101_2 1123360.thalar_02734 6.15e-27 108.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM Belongs to the mannose-6-phosphate isomerase type 2 family cpsB GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_5268_1 1348635.BBJY01000014_gene789 1.16e-140 415.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XVHW@135623|Vibrionales 135623|Vibrionales E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_19254_1 314345.SPV1_13177 3.92e-118 349.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel ynaI - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_400_1 247490.KSU1_C1449 6.07e-72 227.0 28HMZ@1|root,2Z7WD@2|Bacteria,2J2EK@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_400_2 1217718.ALOU01000007_gene1258 5.12e-37 136.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria 28216|Betaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_7352_1 941824.TCEL_02353 1.57e-22 98.6 COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,36GX1@31979|Clostridiaceae 186801|Clostridia S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_18492_1 644076.SCH4B_1233 3.08e-53 186.0 COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria,1QUQG@1224|Proteobacteria,2TWJ4@28211|Alphaproteobacteria,4NAGY@97050|Ruegeria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4,Fer4_7 k141_12965_1 596154.Alide2_2237 4.82e-157 447.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VIY2@28216|Betaproteobacteria,4AB91@80864|Comamonadaceae 28216|Betaproteobacteria M glycosyl transferase family 2 - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 k141_16380_2 1288826.MSNKSG1_01633 3.67e-97 283.0 COG2030@1|root,COG2030@2|Bacteria,1N4UG@1224|Proteobacteria 1224|Proteobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas k141_8732_3 1278309.KB907099_gene3017 4.37e-68 207.0 COG1544@1|root,COG1544@2|Bacteria,1NB1F@1224|Proteobacteria,1SFM8@1236|Gammaproteobacteria,1XM5P@135619|Oceanospirillales 135619|Oceanospirillales J Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - Ribosomal_S30AE k141_2467_1 1288826.MSNKSG1_17431 2.33e-182 528.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,464HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_17094_1 1278309.KB907100_gene2063 9.23e-112 328.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,1XJAT@135619|Oceanospirillales 135619|Oceanospirillales K 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18 k141_15744_1 270374.MELB17_23350 2.96e-135 398.0 COG0477@1|root,COG2814@2|Bacteria,1QV32@1224|Proteobacteria,1T3MY@1236|Gammaproteobacteria,46D5H@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 k141_15744_2 1288826.MSNKSG1_15427 1.25e-151 426.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1RYVQ@1236|Gammaproteobacteria,46AJX@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1881 Phospholipid-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP k141_15744_3 1288826.MSNKSG1_15422 7e-36 127.0 COG0666@1|root,COG0666@2|Bacteria,1RE5N@1224|Proteobacteria,1SYU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AnkB protein involved in protection against oxygen ankB - - ko:K06867 - - - - ko00000 - - - Ank_2 k141_15744_4 1288826.MSNKSG1_15417 1.68e-131 373.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_15744_5 1288826.MSNKSG1_15412 2.91e-312 851.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,464B3@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1252 NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_15744_6 1288826.MSNKSG1_15407 0.0 875.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,466BN@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iEC042_1314.EC042_2517,iSbBS512_1146.SbBS512_E2652 Proton_antipo_M k141_15744_7 1288826.MSNKSG1_15402 0.0 1001.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4664Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iSDY_1059.SDY_2473 Proton_antipo_M k141_15744_8 1288826.MSNKSG1_15397 1.09e-192 549.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,469GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945 Proton_antipo_M,Proton_antipo_N k141_21326_1 323848.Nmul_A1750 8.33e-21 85.5 COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,373MH@32003|Nitrosomonadales 28216|Betaproteobacteria CO Glutaredoxin-like domain (DUF836) - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - DUF836 k141_21326_2 1499967.BAYZ01000171_gene5617 1.42e-09 62.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf htrA GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_16551_2 1415779.JOMH01000001_gene966 3.5e-34 129.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1X60V@135614|Xanthomonadales 135614|Xanthomonadales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_1273_1 794846.AJQU01000079_gene5631 3.96e-84 278.0 COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2TW1J@28211|Alphaproteobacteria,4B7HQ@82115|Rhizobiaceae 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,Response_reg k141_22149_1 1278309.KB907106_gene1219 3.53e-149 421.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XHWY@135619|Oceanospirillales 135619|Oceanospirillales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_22149_2 1278309.KB907106_gene1220 2.3e-140 397.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_4763_2 857087.Metme_4588 5.82e-38 142.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XENC@135618|Methylococcales 135618|Methylococcales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_18019_1 697282.Mettu_1490 7.91e-85 266.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XEM6@135618|Methylococcales 135618|Methylococcales F Thymidine phosphorylase - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_9530_1 351016.RAZWK3B_07859 7.04e-104 319.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,2P13H@2433|Roseobacter 28211|Alphaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases prpE - 6.2.1.1,6.2.1.17 ko:K01895,ko:K01908 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_11681_1 1049564.TevJSym_bv00090 6.01e-12 69.7 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1J6SC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_11681_2 948565.AFFP02000019_gene1400 3.12e-52 175.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1Y710@135625|Pasteurellales 135625|Pasteurellales L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_10303_1 292415.Tbd_1500 5.13e-195 563.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales 119069|Hydrogenophilales C Inorganic H+ pyrophosphatase - - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k141_20725_1 189753.AXAS01000018_gene3199 2.52e-09 60.5 COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2U0G2@28211|Alphaproteobacteria,3JXD2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Bacterial transcriptional repressor C-terminal - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_13,TetR_N k141_556_1 395493.BegalDRAFT_2006 2.88e-96 294.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,45ZT0@72273|Thiotrichales 72273|Thiotrichales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_15897_2 314345.SPV1_04123 2.66e-74 247.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria 1224|Proteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family czcA - - ko:K07239,ko:K15726 - - - - ko00000,ko02000 2.A.6.1,2.A.6.1.2 - - ACR_tran k141_1945_1 1122201.AUAZ01000001_gene2280 1.02e-166 470.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,4640A@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rmlA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_1945_2 1479237.JMLY01000001_gene1825 1.81e-79 245.0 COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,4652A@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_1929,iEcHS_1320.EcHS_A2180 RmlD_sub_bind k141_18020_1 264198.Reut_A3091 1.45e-57 187.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1K1CF@119060|Burkholderiaceae 28216|Betaproteobacteria P Cytochrome C1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_22150_1 1215092.PA6_016_00200 1.18e-05 47.8 2E9Z2@1|root,3344J@2|Bacteria,1N825@1224|Proteobacteria,1SE0S@1236|Gammaproteobacteria,1YGYP@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_17254_1 1163617.SCD_n01387 6.93e-97 296.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria 28216|Betaproteobacteria S Belongs to the GcvT family ygfZ - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_17254_2 765911.Thivi_4351 1.2e-19 84.7 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1SEBT@1236|Gammaproteobacteria,1WZ6I@135613|Chromatiales 135613|Chromatiales C TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_15898_1 522306.CAP2UW1_0935 1.02e-40 146.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase spkD - - - - - - - - - - - Pkinase k141_6738_1 330214.NIDE0211 5.15e-70 222.0 COG3496@1|root,COG3496@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1365) - - 2.1.1.79 ko:K00574,ko:K09701 - - - - ko00000,ko01000 - - - DUF1365 k141_6738_2 472759.Nhal_0313 9.54e-129 381.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1WX07@135613|Chromatiales 135613|Chromatiales M PFAM Cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_21489_1 396588.Tgr7_2774 3.88e-97 298.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_8260_1 1288826.MSNKSG1_08163 3.86e-123 358.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_8260_2 1288826.MSNKSG1_08168 0.0 985.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,464YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 k141_8260_3 1288826.MSNKSG1_08173 0.0 1123.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,465EM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Oxygen tolerance batD - - - - - - - - - - - BatD k141_8260_4 1288826.MSNKSG1_08178 1.61e-290 795.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1S358@1236|Gammaproteobacteria,466S6@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG4235 Cytochrome c biogenesis factor ccmI - - ko:K02200 - - - - ko00000 - - - TPR_14,TPR_16,TPR_2,TPR_8 k141_8260_5 1288826.MSNKSG1_08183 1.9e-89 265.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,467TB@72275|Alteromonadaceae 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200 - - - - ko00000 - - - CcmH k141_8260_6 1288826.MSNKSG1_08188 4.11e-115 331.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,4670V@72275|Alteromonadaceae 1236|Gammaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins - - - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_8260_7 1288826.MSNKSG1_08193 0.0 1250.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4649T@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1138 Cytochrome c biogenesis factor ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_8260_8 1288826.MSNKSG1_08198 1.63e-103 300.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,467DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - ko:K02197 - - - - ko00000 - - iSSON_1240.SSON_2255 CcmE k141_8260_9 1288826.MSNKSG1_08203 1.03e-21 85.9 COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria,4691H@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735 CcmD k141_557_1 765914.ThisiDRAFT_1981 2.7e-78 251.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_3359_2 1415779.JOMH01000001_gene2452 8.24e-77 236.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,1X605@135614|Xanthomonadales 135614|Xanthomonadales U MotA/TolQ/ExbB proton channel family - - - - - - - - - - - - MotA_ExbB k141_3359_3 626887.J057_16805 2.12e-28 108.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_4765_1 485918.Cpin_5618 7.5e-24 95.5 COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1ISJ5@117747|Sphingobacteriia 976|Bacteroidetes I Beta-carotene hydroxylase crtZ - 1.14.15.24 ko:K15746 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00372 R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747 RC00478,RC00704,RC02629 ko00000,ko00001,ko00002,ko01000 - - - FA_hydroxylase k141_18022_1 550540.Fbal_0195 6.89e-58 191.0 COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_15148_1 1288826.MSNKSG1_16126 1.5e-274 752.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria,4674G@72275|Alteromonadaceae 1236|Gammaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrB GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_15148_2 1288826.MSNKSG1_16131 4.01e-178 495.0 COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria,46CUT@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_15148_3 1288826.MSNKSG1_16136 6.68e-181 518.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,46521@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains VP1725 - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_10304_1 1123401.JHYQ01000005_gene269 1.11e-52 175.0 2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM CRISPR-associated protein - - - - - - - - - - - - Cas6 k141_10304_2 910964.GEAM_1087 1.38e-18 81.3 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P part of a sulfur-relay system tusE GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_22152_1 765910.MARPU_15335 9.34e-44 162.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2,sCache_2 k141_12448_1 1288826.MSNKSG1_01243 4.4e-123 353.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,4650X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_15923_1 743722.Sph21_4522 3.73e-48 161.0 COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,1ISAB@117747|Sphingobacteriia 976|Bacteroidetes O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin k141_17275_1 1415756.JQMY01000001_gene3613 7.83e-107 327.0 COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,2PCJE@252301|Oceanicola 28211|Alphaproteobacteria F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations amn GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008714,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - AMNp_N,PNP_UDP_1 k141_3369_1 443152.MDG893_13119 9.92e-35 126.0 COG2356@1|root,COG2356@2|Bacteria,1RI3H@1224|Proteobacteria,1S6A9@1236|Gammaproteobacteria,4681D@72275|Alteromonadaceae 1236|Gammaproteobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 k141_18039_2 1288826.MSNKSG1_06208 4.81e-105 316.0 COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria,1SD6Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HD superfamily - - - ko:K06885 - - - - ko00000 - - - HD k141_22177_1 640511.BC1002_0386 1.57e-39 150.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,Response_reg k141_9545_2 754477.Q7C_1794 5.37e-139 410.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_4777_2 1278309.KB907100_gene1989 0.0 908.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XIGF@135619|Oceanospirillales 135619|Oceanospirillales E glutamate synthase gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 k141_4777_3 1278309.KB907100_gene1990 0.0 2706.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XHTM@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_4777_4 1278309.KB907100_gene1991 1.6e-193 558.0 COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,1XJX1@135619|Oceanospirillales 135619|Oceanospirillales U AAA domain - - - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR k141_4777_5 1278309.KB907100_gene1992 2.97e-163 463.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XH38@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_7531_1 1278309.KB907100_gene2127 2.5e-241 677.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XIYK@135619|Oceanospirillales 135619|Oceanospirillales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_7531_2 1278309.KB907100_gene2128 1.55e-293 809.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XIJ5@135619|Oceanospirillales 135619|Oceanospirillales O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_7531_3 1278309.KB907100_gene2129 4.11e-49 172.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_3370_1 1129794.C427_4175 4.79e-65 208.0 COG1216@1|root,COG1216@2|Bacteria,1NB0V@1224|Proteobacteria,1RYKK@1236|Gammaproteobacteria,4653V@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_2 k141_14430_1 713586.KB900536_gene2033 2.4e-49 161.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,1SAXA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P belongs to the Fur family - - - ko:K09826 - - - - ko00000,ko03000 - - - FUR k141_14430_2 396588.Tgr7_3234 3.25e-56 186.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1WWA9@135613|Chromatiales 135613|Chromatiales C PFAM FAD dependent oxidoreductase - - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_16567_1 643473.KB235930_gene1836 2.58e-113 337.0 COG0604@1|root,COG0604@2|Bacteria,1FZW8@1117|Cyanobacteria,1HKMY@1161|Nostocales 1117|Cyanobacteria C PFAM Alcohol dehydrogenase GroES-like domain - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_16567_2 1121939.L861_05420 4.54e-07 51.6 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales 135619|Oceanospirillales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine - - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_18040_1 2340.JV46_03650 3.12e-45 155.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_18040_2 1238190.AMQY01000011_gene1905 4.75e-37 138.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales 135619|Oceanospirillales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_11051_1 391613.RTM1035_14012 6.61e-37 135.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,46NP2@74030|Roseovarius 28211|Alphaproteobacteria H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_5471_1 5341.XP_007335113.1 6.1e-48 169.0 2C400@1|root,2S2UT@2759|Eukaryota,3A0X5@33154|Opisthokonta,3P2I4@4751|Fungi,3V0CD@5204|Basidiomycota 4751|Fungi I LAGLIDADG endonuclease - - - - - - - - - - - - LAGLIDADG_1 k141_5471_2 1248917.ANFX01000037_gene2048 7.24e-32 124.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2K034@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_5471_4 1337093.MBE-LCI_0020 2.82e-14 76.3 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2P84N@245186|Loktanella 28211|Alphaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_5471_5 82508.K1V936 1.11e-23 108.0 COG0843@1|root,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3NYGG@4751|Fungi,3V05I@5204|Basidiomycota 4751|Fungi Q Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B cox1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.9.3.1 ko:K02256 ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016 M00154 - - ko00000,ko00001,ko00002,ko01000,ko03029 3.D.4.11,3.D.4.7,3.D.4.8 - - COX1,LAGLIDADG_1 k141_6764_1 595494.Tola_0827 1.84e-107 327.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1Y3VZ@135624|Aeromonadales 135624|Aeromonadales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_2627_1 768671.ThimaDRAFT_2283 7.1e-105 318.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1WWI5@135613|Chromatiales 135613|Chromatiales H Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - - - - - - - - - - HemN_C,Radical_SAM k141_7532_1 1028803.GG9_1366 5.62e-73 223.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1Y7ZY@135625|Pasteurellales 135625|Pasteurellales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_7532_2 575588.ACPN01000095_gene337 8.79e-19 80.9 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,3NP0A@468|Moraxellaceae 1236|Gammaproteobacteria J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_3993_1 321846.PS417_24275 3.75e-69 238.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase morA - - - - - - - - - - - EAL,GGDEF,PAS,PAS_8,PAS_9,dCache_2 k141_13153_1 1392540.P256_01408 4.57e-18 82.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,3NJ9G@468|Moraxellaceae 1236|Gammaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Ubie_methyltran k141_13153_2 1288494.EBAPG3_2480 6.04e-59 186.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,3734V@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 k141_13153_3 105559.Nwat_2187 2.08e-221 622.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales 135613|Chromatiales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_13153_4 765911.Thivi_1736 7.29e-92 273.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales 135613|Chromatiales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_18800_1 1120919.AUBI01000003_gene1542 1.26e-41 145.0 COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2U4DJ@28211|Alphaproteobacteria,2JTG8@204441|Rhodospirillales 204441|Rhodospirillales S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD k141_18800_2 1046724.KB889827_gene2627 4.18e-23 102.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_9001_1 1288826.MSNKSG1_06643 7.71e-118 362.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AM7@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT - - ko:K03556 - - - - ko00000,ko03000 - - - GerE,TPR_19,TPR_4,TPR_8 k141_5570_1 3880.AES69829 4.87e-97 305.0 COG0048@1|root,COG0049@1|root,COG1007@1|root,KOG1750@2759|Eukaryota,KOG3291@2759|Eukaryota,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,4JNJF@91835|fabids 35493|Streptophyta C NAD(P)H-quinone oxidoreductase subunit 2 ndhB - 1.6.5.3 ko:K02992,ko:K05573 ko00190,ko01100,ko03010,map00190,map01100,map03010 M00145,M00178,M00179 R11945 RC00061 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - Proton_antipo_M k141_15219_1 1353531.AZNX01000006_gene5842 9.24e-21 93.2 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,4B8XV@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glycine D-amino acid oxidases (deaminating) - - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_15219_2 1002340.AFCF01000011_gene2584 1.66e-25 99.4 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,34EBS@302485|Phaeobacter 28211|Alphaproteobacteria E Imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03013,R03243,R03457 RC00006,RC00017,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 - - - IGPD k141_17375_1 1232683.ADIMK_0867 1.96e-79 265.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_2741_1 1288826.MSNKSG1_06128 2.57e-124 369.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,465RH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_19478_2 1453501.JELR01000002_gene342 4.63e-20 90.1 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_11766_1 998674.ATTE01000001_gene4576 1.23e-65 224.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,45ZVC@72273|Thiotrichales 72273|Thiotrichales C Oxidizes proline to glutamate for use as a carbon and nitrogen source - - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_2036_1 1485545.JQLW01000012_gene1691 1.69e-63 203.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria 1224|Proteobacteria L Belongs to the pirin family yhhW_2 - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_16687_1 639283.Snov_1062 8.1e-18 79.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,3EZS2@335928|Xanthobacteraceae 28211|Alphaproteobacteria P ArsC family MA20_27840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_6232_1 1278309.KB907102_gene253 0.0 980.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1XIQA@135619|Oceanospirillales 135619|Oceanospirillales CH Phenol hydroxylase, C-terminal dimerisation domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_15234_5 1278309.KB907100_gene2340 1.76e-115 333.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1XK1Z@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_15234_6 1278309.KB907100_gene2339 3.15e-93 276.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,1XJI2@135619|Oceanospirillales 135619|Oceanospirillales H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC - 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - - Chor_lyase k141_15234_7 1278309.KB907100_gene2338 3.88e-164 464.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XH95@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_15234_8 1278309.KB907100_gene2337 7.77e-102 298.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XHIV@135619|Oceanospirillales 135619|Oceanospirillales T phosphate regulon transcriptional regulatory protein PhoB phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_11782_1 2880.D7FIE5 1.12e-22 96.7 28TMI@1|root,2S5Q9@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - Spond_N k141_9683_1 1121930.AQXG01000008_gene122 1.06e-13 69.7 COG0500@1|root,COG2226@2|Bacteria,4NMYN@976|Bacteroidetes,1J03R@117747|Sphingobacteriia 976|Bacteroidetes Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_31 k141_9683_2 56780.SYN_02429 6.8e-07 50.1 COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT k141_16712_1 1288826.MSNKSG1_03966 8.7e-81 265.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,464YY@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_16712_2 1288826.MSNKSG1_03971 1.05e-222 614.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,4649J@72275|Alteromonadaceae 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 ACCA k141_18818_1 555778.Hneap_0397 7.76e-111 327.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1X2C7@135613|Chromatiales 135613|Chromatiales P binding-protein-dependent transport systems inner membrane component - - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k141_19505_1 1123278.KB893553_gene3918 1.83e-24 101.0 arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes,47Q9D@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_19505_2 1163617.SCD_n02770 2.26e-36 130.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria 28216|Betaproteobacteria C cytochrome nosC - - - - - - - - - - - Cytochrome_CBB3 k141_19505_3 323261.Noc_2002 6.39e-210 605.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWQV@135613|Chromatiales 135613|Chromatiales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_2777_1 935261.JAGL01000005_gene3349 3.14e-07 54.3 COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2U7P9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NT Chemotaxis protein cheW cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_2777_2 1179778.PMM47T1_00955 9.68e-52 166.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S4NE@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT Type IV pilus response regulator PilH pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_11783_1 1237149.C900_05608 1.04e-61 202.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,47KAQ@768503|Cytophagia 976|Bacteroidetes F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,ASL_C,Lyase_1 k141_15235_1 697282.Mettu_4306 4.26e-10 59.7 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1XEFH@135618|Methylococcales 135618|Methylococcales H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_15235_2 1198232.CYCME_0544 2.44e-43 149.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,4616Y@72273|Thiotrichales 72273|Thiotrichales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_14570_1 1278309.KB907110_gene3152 1.25e-119 344.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1XS75@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin - - - - - - - - - - - - Thioredoxin_5 k141_14570_2 1278309.KB907110_gene3153 1.51e-80 240.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XKUQ@135619|Oceanospirillales 135619|Oceanospirillales K Cold-shock' - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_14570_3 1278309.KB907110_gene3154 9.45e-07 47.0 COG2900@1|root,COG2900@2|Bacteria 2|Bacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_19506_1 1211777.BN77_p11302 1.39e-28 116.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,4B72G@82115|Rhizobiaceae 28211|Alphaproteobacteria E Belongs to the GMC oxidoreductase family - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_9684_1 313596.RB2501_06350 3.7e-87 285.0 COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia 976|Bacteroidetes G BNR Asp-box repeat - - - - - - - - - - - - BNR,BNR_6,Sortilin-Vps10 k141_7662_2 272630.MexAM1_META1p2277 1.11e-10 61.2 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2TT86@28211|Alphaproteobacteria,1JRTX@119045|Methylobacteriaceae 28211|Alphaproteobacteria J Belongs to the pseudouridine synthase RsuA family rsuA - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_9040_1 869213.JCM21142_93376 1.53e-77 245.0 COG4773@1|root,COG4773@2|Bacteria,4PKEB@976|Bacteroidetes 976|Bacteroidetes P Receptor - - - - - - - - - - - - - k141_20076_1 1278309.KB907099_gene2988 1.56e-280 775.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XHCS@135619|Oceanospirillales 135619|Oceanospirillales C sodium proton antiporter - - - - - - - - - - - - Na_H_antiporter k141_20076_2 1278309.KB907099_gene2989 2.68e-292 800.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XHUF@135619|Oceanospirillales 135619|Oceanospirillales E Oxidoreductase - - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO k141_20076_3 1278309.KB907099_gene2990 4.25e-176 496.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XIAR@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_20076_4 1278309.KB907099_gene2991 4.57e-223 617.0 COG1638@1|root,COG1638@2|Bacteria,1QWNV@1224|Proteobacteria,1RQXG@1236|Gammaproteobacteria,1XIYU@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_20076_5 1278309.KB907099_gene2992 1.18e-94 278.0 COG4665@1|root,COG4665@2|Bacteria,1RDP0@1224|Proteobacteria,1S4A5@1236|Gammaproteobacteria,1XJR2@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - - - - - - - - - - DctQ k141_20076_6 1278309.KB907099_gene2993 9.29e-129 376.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XICB@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_17412_1 1123392.AQWL01000003_gene172 3.38e-84 268.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,1KRS1@119069|Hydrogenophilales 119069|Hydrogenophilales P NnrS protein - - - ko:K07234 - - - - ko00000 - - - NnrS k141_17412_2 1232410.KI421413_gene485 3.73e-84 257.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,43UFH@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH k141_11784_2 1006004.GBAG_3223 3.69e-39 135.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the CinA family ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_9685_1 398580.Dshi_2150 6.96e-14 72.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2TS4G@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_9685_2 367336.OM2255_03835 7.78e-54 179.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_19507_1 1417296.U879_11325 7.71e-16 77.4 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria 28211|Alphaproteobacteria L double-strand break repair protein AddB addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_19507_2 367336.OM2255_09156 2.36e-69 218.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria 28211|Alphaproteobacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) MA20_24100 - 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_3,NTP_transferase k141_9041_2 998674.ATTE01000001_gene4277 2.11e-76 231.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,460JG@72273|Thiotrichales 72273|Thiotrichales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_2778_1 1122194.AUHU01000003_gene2306 3.15e-15 82.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_2778_2 1134474.O59_000842 2.14e-11 64.3 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1FHFW@10|Cellvibrio 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_4054_1 396588.Tgr7_2896 6.5e-152 432.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1WW0T@135613|Chromatiales 135613|Chromatiales E PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_4054_2 1198232.CYCME_0263 7.85e-211 592.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,461TD@72273|Thiotrichales 72273|Thiotrichales H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k141_19508_1 1121930.AQXG01000014_gene350 8.78e-11 68.2 COG1404@1|root,COG2356@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4PI1X@976|Bacteroidetes,1IXYZ@117747|Sphingobacteriia 976|Bacteroidetes L Endonuclease I - - - - - - - - - - - - Endonuclease_1 k141_7663_1 1278309.KB907100_gene2266 3.55e-175 499.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XJB4@135619|Oceanospirillales 135619|Oceanospirillales LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_14574_1 768671.ThimaDRAFT_0088 5.62e-42 153.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_15238_1 290398.Csal_1184 4.05e-51 175.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XHCS@135619|Oceanospirillales 135619|Oceanospirillales C sodium proton antiporter - - - - - - - - - - - - Na_H_antiporter k141_9042_1 472759.Nhal_3577 1.01e-64 211.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_9042_2 1034943.BN1094_03271 3.55e-19 82.4 COG1993@1|root,COG1993@2|Bacteria,1N8TP@1224|Proteobacteria,1SDYH@1236|Gammaproteobacteria,1JF4D@118969|Legionellales 118969|Legionellales S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 k141_9042_3 1198232.CYCME_1173 1.36e-05 45.4 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,460WA@72273|Thiotrichales 72273|Thiotrichales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_19509_1 1123368.AUIS01000026_gene1464 9.39e-87 277.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,2NBVQ@225057|Acidithiobacillales 225057|Acidithiobacillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_4055_1 1123514.KB905899_gene1590 5.05e-71 219.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,460P8@72273|Thiotrichales 72273|Thiotrichales S DoxX - - - - - - - - - - - - DoxX k141_20079_1 1120999.JONM01000001_gene1363 6.73e-111 332.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KPVQ@206351|Neisseriales 206351|Neisseriales O Peptidase, U32 family - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_19510_1 1121380.JNIW01000052_gene3281 6.14e-05 48.9 COG0404@1|root,COG0404@2|Bacteria,1WI4H@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_16713_1 1278309.KB907100_gene2165 8.57e-155 439.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XIF6@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_16713_2 1278309.KB907100_gene2166 1.47e-159 452.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1XJAJ@135619|Oceanospirillales 135619|Oceanospirillales GM epimerase - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_16713_3 1278309.KB907100_gene2167 5.73e-159 447.0 COG4160@1|root,COG4160@2|Bacteria,1QV6B@1224|Proteobacteria,1RNC2@1236|Gammaproteobacteria,1XS3W@135619|Oceanospirillales 135619|Oceanospirillales E transporter, permease - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_16713_4 1278309.KB907100_gene2168 5.78e-126 362.0 COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1SYC9@1236|Gammaproteobacteria,1XRJI@135619|Oceanospirillales 135619|Oceanospirillales P (ABC) transporter - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_20080_1 1286106.MPL1_09942 4.01e-18 80.9 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,46132@72273|Thiotrichales 72273|Thiotrichales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_7664_1 1232683.ADIMK_3856 1.88e-64 209.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,464TY@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases atzB - 3.5.4.32 ko:K18456 - - - - ko00000,ko01000 - - - Amidohydro_1 k141_7664_2 1232683.ADIMK_3857 1.88e-251 699.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,4646X@72275|Alteromonadaceae 1236|Gammaproteobacteria F xanthine xanQ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16345,ko:K16346 - - - - ko00000,ko02000 2.A.40,2.A.40.4.2,2.A.40.4.3 - iG2583_1286.G2583_3536 Xan_ur_permease k141_9043_1 768066.HELO_4019 3.33e-123 362.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1XI99@135619|Oceanospirillales 135619|Oceanospirillales L glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_20081_1 443152.MDG893_09206 8.32e-75 229.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,46701@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG3023 Negative regulator of beta-lactamase expression ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Amidase_2 k141_19511_1 105559.Nwat_0344 7.26e-50 181.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_9689_2 990285.RGCCGE502_05889 1.38e-24 96.7 COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,2UCF1@28211|Alphaproteobacteria,4BG7X@82115|Rhizobiaceae 28211|Alphaproteobacteria T DnaK suppressor protein dskA - - - - - - - - - - - zf-dskA_traR k141_16715_1 1049564.TevJSym_as00020 2.12e-123 369.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1J4JE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 k141_17415_1 994573.T472_0210520 1.1e-05 54.7 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,36FQG@31979|Clostridiaceae 186801|Clostridia M PFAM NLP P60 protein - - - ko:K11060,ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011,ko02042 - - - NLPC_P60,SH3_3 k141_17415_2 1278309.KB907099_gene3015 1.69e-162 466.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XIPG@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_2779_1 857087.Metme_1556 0.000121 42.7 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,1S25M@1236|Gammaproteobacteria,1XGQZ@135618|Methylococcales 135618|Methylococcales H 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt k141_2779_2 333138.LQ50_06790 3.36e-51 175.0 COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily ylbK GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_2779_3 1123393.KB891327_gene404 6e-102 305.0 28HKZ@1|root,2Z7VP@2|Bacteria,1R4QW@1224|Proteobacteria,2VMSD@28216|Betaproteobacteria,1KSB6@119069|Hydrogenophilales 119069|Hydrogenophilales S Protein of unknown function (DUF3050) - - - - - - - - - - - - DUF3050 k141_2779_4 94122.Shewana3_0540 2.12e-44 153.0 28M05@1|root,2ZB16@2|Bacteria,1QVZ0@1224|Proteobacteria,1T2NG@1236|Gammaproteobacteria,2QEST@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - YkuI_C k141_6332_1 1122197.ATWI01000011_gene441 9.48e-34 120.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,4681G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_6332_2 1318628.MARLIPOL_04535 4.79e-34 126.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k141_14730_1 396588.Tgr7_1832 5.26e-91 278.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales 135613|Chromatiales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_7041_1 1278309.KB907100_gene2096 2.31e-242 693.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales 135619|Oceanospirillales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_766_1 349124.Hhal_2240 3.1e-88 271.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_13332_1 536019.Mesop_0019 1.69e-36 129.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,43K27@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_13332_2 1122137.AQXF01000001_gene3023 6.3e-63 213.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_21029_2 1288826.MSNKSG1_10748 3.33e-144 412.0 COG0640@1|root,COG4976@1|root,COG0640@2|Bacteria,COG4976@2|Bacteria,1NFSV@1224|Proteobacteria,1RQT6@1236|Gammaproteobacteria,464PH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_23,Methyltransf_31 k141_7757_1 1122599.AUGR01000003_gene2010 5.27e-156 455.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,1XIH9@135619|Oceanospirillales 135619|Oceanospirillales I Acetyl-coenzyme A synthetase N-terminus - - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_9820_1 1122599.AUGR01000009_gene2460 1.36e-194 556.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,1XJ6B@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase-like ATPases - - - - - - - - - - - - CHASE5,HATPase_c k141_18194_1 314278.NB231_12364 3.05e-13 67.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales 135613|Chromatiales E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 k141_18194_2 472759.Nhal_0649 3.81e-75 228.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WY4F@135613|Chromatiales 135613|Chromatiales O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_18194_3 1121116.KB894765_gene728 2.5e-10 60.5 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,4AB5U@80864|Comamonadaceae 28216|Betaproteobacteria T SMART Nucleotide binding protein, PINc phoH - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_16800_1 399739.Pmen_0965 3.9e-102 310.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1YDVE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Bacterial regulatory protein, Fis family pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_16800_2 1131553.JIBI01000064_gene1047 2.44e-14 75.1 COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,2WGR4@28216|Betaproteobacteria,372VJ@32003|Nitrosomonadales 28216|Betaproteobacteria T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 k141_6333_1 351348.Maqu_1436 5.33e-36 139.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,464XN@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_3559_1 1286106.MPL1_06717 6.22e-167 508.0 COG0247@1|root,COG0277@1|root,COG0437@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0437@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales 72273|Thiotrichales C Domain of unknown function (DUF3400) - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_20306_1 1051985.l11_09310 1.49e-06 52.4 2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VVXN@28216|Betaproteobacteria,2KRZI@206351|Neisseriales 206351|Neisseriales S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF4149 k141_20306_2 1168067.JAGP01000001_gene1557 8.45e-12 62.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,460KM@72273|Thiotrichales 72273|Thiotrichales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_15430_2 1089553.Tph_c18890 8.35e-60 199.0 COG1266@1|root,COG1266@2|Bacteria,1UYGJ@1239|Firmicutes,24CIZ@186801|Clostridia 186801|Clostridia S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_16095_1 1395516.PMO01_10260 5.05e-69 218.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_14731_1 187272.Mlg_0428 5.39e-53 186.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales 135613|Chromatiales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_4240_1 555778.Hneap_2189 1.6e-23 97.4 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WVXA@135613|Chromatiales 135613|Chromatiales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_5679_2 1144343.PMI41_03171 1.52e-56 186.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43HHC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V ABC transporter hndI GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_2854_1 1123237.Salmuc_00492 3.75e-89 271.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_2155_2 396588.Tgr7_0954 2.25e-54 179.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales 135613|Chromatiales Q PFAM methyltransferase - - - - - - - - - - - - Methyltransf_11 k141_18892_1 765914.ThisiDRAFT_0954 8.42e-167 483.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1WX9B@135613|Chromatiales 135613|Chromatiales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_18892_2 1026882.MAMP_00095 2.65e-14 71.6 COG2433@1|root,COG2433@2|Bacteria,1QWB7@1224|Proteobacteria,1T3FV@1236|Gammaproteobacteria,463WV@72273|Thiotrichales 72273|Thiotrichales S Bacterial SH3 domain homologues - - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_11264_1 1288826.MSNKSG1_06438 5.54e-179 513.0 COG3170@1|root,COG3170@2|Bacteria,1N393@1224|Proteobacteria,1SFZT@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_11264_2 1288826.MSNKSG1_06443 1.63e-100 299.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae 1236|Gammaproteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 DAHP_synth_1 k141_7758_2 296591.Bpro_3366 4.26e-28 105.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2VU4G@28216|Betaproteobacteria,4AEVT@80864|Comamonadaceae 28216|Betaproteobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT k141_11935_1 1278309.KB907103_gene1163 3.09e-86 262.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XHH6@135619|Oceanospirillales 135619|Oceanospirillales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF-1 - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_11935_2 1278309.KB907103_gene1162 0.0 1290.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XHUH@135619|Oceanospirillales 135619|Oceanospirillales C Isocitrate dehydrogenase - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_11935_3 1122599.AUGR01000009_gene2495 2.27e-138 404.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1XHG8@135619|Oceanospirillales 135619|Oceanospirillales C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_16801_1 1333856.L686_04510 2.56e-33 126.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1Z1JK@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S DinB superfamily egtB - - - - - - - - - - - DinB_2,FGE-sulfatase k141_16801_2 1158760.AQXP01000048_gene1158 8.42e-07 49.7 COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1WZFF@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 k141_3560_1 314256.OG2516_02269 1.91e-18 84.3 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,2PDRQ@252301|Oceanicola 28211|Alphaproteobacteria S Protein of unknown function (DUF1223) MA20_43790 - - - - - - - - - - - DUF1223 k141_3560_2 1122614.JHZF01000011_gene1076 6.55e-09 56.6 COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria,2PD1E@252301|Oceanicola 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_8430_1 1298858.AUEL01000013_gene5054 1.43e-86 269.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,43H3N@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U pilus assembly protein ATPase CpaF cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_6334_1 1150599.MPHLEI_02793 9.84e-13 73.9 COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae 201174|Actinobacteria M Protein conserved in bacteria - - - - - - - - - - - - Cadherin_3,RCC1_2 k141_15431_1 367336.OM2255_11120 2.92e-65 204.0 COG3793@1|root,COG3793@2|Bacteria,1RD1X@1224|Proteobacteria,2U788@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM Mo-dependent nitrogenase - - - - - - - - - - - - TerB k141_60_1 420662.Mpe_A3089 7.13e-33 125.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VPC5@28216|Betaproteobacteria,1KJQT@119065|unclassified Burkholderiales 28216|Betaproteobacteria P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_767_1 7918.ENSLOCP00000008648 0.000128 50.8 COG0664@1|root,KOG0614@2759|Eukaryota,3AH8Y@33154|Opisthokonta,3BA35@33208|Metazoa,3CRYY@33213|Bilateria,47ZK6@7711|Chordata,491XR@7742|Vertebrata,4A0HG@7898|Actinopterygii 33208|Metazoa T Protein kinase, cGMP-dependent, type II PRKG2 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004690,GO:0004692,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006884,GO:0006950,GO:0006970,GO:0006971,GO:0007154,GO:0007165,GO:0007623,GO:0008104,GO:0008150,GO:0008152,GO:0008361,GO:0009628,GO:0009987,GO:0010468,GO:0012505,GO:0016020,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019222,GO:0019538,GO:0019725,GO:0023052,GO:0031090,GO:0031965,GO:0031967,GO:0031975,GO:0032501,GO:0032535,GO:0032879,GO:0032922,GO:0033036,GO:0033554,GO:0034613,GO:0036211,GO:0036289,GO:0042592,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043271,GO:0043412,GO:0044070,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045794,GO:0046777,GO:0046983,GO:0048511,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051179,GO:0051186,GO:0051641,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070727,GO:0071214,GO:0071470,GO:0071476,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0090066,GO:0104004,GO:0140096,GO:1901564,GO:1903792,GO:1990778,GO:2001225,GO:2001226 2.7.11.12 ko:K19477 ko04022,ko04540,ko04611,ko04713,ko04714,ko04730,ko04740,ko04923,ko04924,ko04970,map04022,map04540,map04611,map04713,map04714,map04730,map04740,map04923,map04924,map04970 - - - ko00000,ko00001,ko01000,ko01001 - - - Pkinase,cNMP_binding k141_16096_1 1316932.MHH_c18830 7.25e-22 94.0 2DQ83@1|root,3357Y@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3800) - - - - - - - - - - - - DUF3800 k141_18893_1 1122614.JHZF01000004_gene315 4.32e-69 212.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria,2PDIA@252301|Oceanicola 28211|Alphaproteobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_4241_1 396588.Tgr7_2235 7.19e-69 216.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_4241_2 1121937.AUHJ01000007_gene1904 8.81e-23 96.3 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,464S4@72275|Alteromonadaceae 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_10531_1 1278309.KB907107_gene1695 6.08e-172 494.0 COG3144@1|root,COG3144@2|Bacteria,1MV22@1224|Proteobacteria,1SCC6@1236|Gammaproteobacteria,1XKD8@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook-length control protein FliK - - - - - - - - - - - - Flg_hook k141_10531_2 1232683.ADIMK_1521 3.46e-33 117.0 COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,1SCWV@1236|Gammaproteobacteria,468FB@72275|Alteromonadaceae 1236|Gammaproteobacteria N homolog of the cytoplasmic domain of flagellar protein FhlB flhB2 - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 k141_10531_3 1278309.KB907107_gene1697 6.04e-73 220.0 2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1XKJY@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2802) - - - - - - - - - - - - DUF2802 k141_10531_4 1278309.KB907107_gene1698 2.89e-70 215.0 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XK35@135619|Oceanospirillales 135619|Oceanospirillales NT CheW-like domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_20307_1 187272.Mlg_2599 1.06e-26 105.0 COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria,1X0TI@135613|Chromatiales 135613|Chromatiales C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_20307_2 748247.AZKH_1492 3.27e-181 524.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k141_9821_1 472759.Nhal_2479 2.52e-147 439.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WXWN@135613|Chromatiales 135613|Chromatiales I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_9821_2 1485544.JQKP01000004_gene510 2.05e-41 151.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,44V2C@713636|Nitrosomonadales 28216|Betaproteobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_21030_2 1288826.MSNKSG1_17156 3.54e-154 433.0 COG1802@1|root,COG1802@2|Bacteria,1RIE7@1224|Proteobacteria,1SM3T@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k141_21030_3 1288826.MSNKSG1_17161 0.0 943.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,464F9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsA GO:0003674,GO:0003824,GO:0008808,GO:0016740,GO:0016772,GO:0016780,GO:0030572 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k141_21030_4 1288826.MSNKSG1_17166 3.93e-113 332.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator oruR - - - - - - - - - - - Arabinose_bd,HTH_18 k141_16802_1 357804.Ping_0336 6.21e-22 98.6 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1S34W@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_9130_1 1122201.AUAZ01000001_gene2244 2.16e-85 259.0 COG0508@1|root,COG0508@2|Bacteria,1RBA8@1224|Proteobacteria,1S3HD@1236|Gammaproteobacteria,46AQW@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh k141_9130_2 1149133.ppKF707_2716 4.01e-24 93.2 COG0508@1|root,COG0508@2|Bacteria,1N9FF@1224|Proteobacteria,1SG3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Biotin-requiring enzyme - - - - - - - - - - - - Biotin_lipoyl k141_9130_3 1232683.ADIMK_0170 6.55e-201 561.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,469N7@72275|Alteromonadaceae 1236|Gammaproteobacteria C Transketolase, pyrimidine binding domain acoB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_9130_4 1232683.ADIMK_0172 8.88e-162 460.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RWHU@1236|Gammaproteobacteria,469IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_13334_1 396595.TK90_2124 1.05e-77 246.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_21656_1 1278309.KB907101_gene559 1.65e-105 309.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria,1XRW6@135619|Oceanospirillales 135619|Oceanospirillales NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k141_21656_2 1278309.KB907101_gene558 7.11e-32 113.0 2DEZY@1|root,2ZPY3@2|Bacteria,1P846@1224|Proteobacteria,1SV9R@1236|Gammaproteobacteria,1XQPH@135619|Oceanospirillales 135619|Oceanospirillales S YfcL protein - - - - - - - - - - - - YfcL k141_21656_3 1278309.KB907101_gene557 1.61e-82 244.0 2F32R@1|root,33VXS@2|Bacteria,1NVT5@1224|Proteobacteria,1SPEK@1236|Gammaproteobacteria,1XQ9T@135619|Oceanospirillales 135619|Oceanospirillales S Immunity protein 22 - - - - - - - - - - - - DUF4284 k141_21656_4 395493.BegalDRAFT_0294 1.46e-29 109.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales 72273|Thiotrichales L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k141_21656_5 1278309.KB907101_gene554 1.61e-103 305.0 292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,1S44V@1236|Gammaproteobacteria,1XKVQ@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3047) - - - - - - - - - - - - DUF3047 k141_21656_6 1278309.KB907101_gene553 0.0 996.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XIKF@135619|Oceanospirillales 135619|Oceanospirillales L DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_21656_8 1122599.AUGR01000002_gene3358 7.13e-147 427.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XNV7@135619|Oceanospirillales 135619|Oceanospirillales P Na+/H+ antiporter 1 - - - - - - - - - - - - Na_H_antiport_1 k141_13360_1 994573.T472_0216770 1.54e-27 105.0 COG4925@1|root,COG4925@2|Bacteria,1V9AI@1239|Firmicutes,24PAJ@186801|Clostridia,36NGF@31979|Clostridiaceae 186801|Clostridia I sulfurtransferase activity - - - - - - - - - - - - Cyclophil_like k141_13360_2 573.JG24_21135 2.33e-09 57.8 COG0599@1|root,COG0599@2|Bacteria,1NN7W@1224|Proteobacteria,1RXXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S decarboxylase - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_3580_1 1085623.GNIT_0115 1.91e-111 333.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,1S63M@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_9148_1 1288826.MSNKSG1_06073 3.55e-144 410.0 COG1073@1|root,COG1073@2|Bacteria,1NX86@1224|Proteobacteria,1T2HF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_9836_1 614083.AWQR01000031_gene2613 7.73e-47 172.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,4AAY1@80864|Comamonadaceae 28216|Betaproteobacteria O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_7055_1 1278309.KB907110_gene3159 1.52e-123 363.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XHNE@135619|Oceanospirillales 135619|Oceanospirillales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_7055_2 1278309.KB907110_gene3158 8.12e-128 365.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1XHWE@135619|Oceanospirillales 135619|Oceanospirillales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_7055_3 1278309.KB907110_gene3157 5.94e-121 350.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1XJBW@135619|Oceanospirillales 135619|Oceanospirillales O Peptidase M22 yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_7055_4 1278309.KB907110_gene3156 6.95e-171 479.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1XH3U@135619|Oceanospirillales 135619|Oceanospirillales V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_7055_5 1278309.KB907110_gene3155 3.27e-113 330.0 COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1XIK1@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the guanosine in position 1516 of 16S rRNA rsmJ - 2.1.1.242 ko:K15984 - - - - ko00000,ko01000,ko03009 - - - SAM_MT k141_8453_1 388413.ALPR1_06770 2.57e-15 77.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia 976|Bacteroidetes C PFAM Aldehyde dehydrogenase gabD - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14043_1 1452718.JBOY01000137_gene1485 2.7e-80 257.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S4YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k141_16109_1 1263831.F543_480 4.86e-25 102.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1Y7QW@135625|Pasteurellales 135625|Pasteurellales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_16109_2 396588.Tgr7_0039 8.4e-41 157.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RWW8@1236|Gammaproteobacteria,1X085@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_2169_1 105559.Nwat_1358 6.52e-38 149.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WW1B@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,Response_reg k141_12643_1 1499686.BN1079_02351 1.71e-46 172.0 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_2872_1 269799.Gmet_1133 1.46e-128 379.0 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WJFR@28221|Deltaproteobacteria,43UUT@69541|Desulfuromonadales 28221|Deltaproteobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_15462_1 269799.Gmet_1132 5.96e-91 278.0 28MU7@1|root,2ZB25@2|Bacteria,1QM5F@1224|Proteobacteria,42TV5@68525|delta/epsilon subdivisions,2WQW0@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF4255) - - - - - - - - - - - - DUF4255 k141_5702_1 1278309.KB907103_gene1030 1.15e-94 279.0 29DT0@1|root,300QV@2|Bacteria,1RGE1@1224|Proteobacteria,1S7BN@1236|Gammaproteobacteria,1XPDA@135619|Oceanospirillales 135619|Oceanospirillales S Cytochrome P460 - - - - - - - - - - - - Cytochrome_P460 k141_5702_2 1278309.KB907103_gene1031 5.9e-106 306.0 2E1EJ@1|root,32WTH@2|Bacteria,1N6AH@1224|Proteobacteria,1SBR0@1236|Gammaproteobacteria,1XNB0@135619|Oceanospirillales 135619|Oceanospirillales S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k141_5702_3 1318628.MARLIPOL_03075 5.22e-53 172.0 COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,1RNPE@1236|Gammaproteobacteria,466EK@72275|Alteromonadaceae 1236|Gammaproteobacteria K histidine utilization repressor hutC - - ko:K05836 - - - - ko00000,ko03000 - - - GntR,UTRA k141_19084_2 1453501.JELR01000001_gene2107 5.14e-17 77.4 COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,4682P@72275|Alteromonadaceae 1236|Gammaproteobacteria S relative of glutathione S-transferase, MAPEG superfamily yecN - - ko:K07136 - - - - ko00000 - - - MAPEG k141_3730_1 870187.Thini_4237 4.46e-113 333.0 COG2253@1|root,COG2253@2|Bacteria,1R3R3@1224|Proteobacteria,1S0PT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii k141_3730_2 13690.CP98_01930 4.55e-61 197.0 COG5340@1|root,COG5340@2|Bacteria,1RGNP@1224|Proteobacteria,2U1VQ@28211|Alphaproteobacteria,2K8M3@204457|Sphingomonadales 204457|Sphingomonadales K Psort location Cytoplasmic, score - - - - - - - - - - - - - k141_14888_1 396588.Tgr7_1549 8.97e-82 251.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1WW21@135613|Chromatiales 135613|Chromatiales M UTP-glucose-1-phosphate uridylyltransferase - - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_7192_1 1175306.GWL_29010 3.06e-55 196.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,473KU@75682|Oxalobacteraceae 28216|Betaproteobacteria E Domain of unknown function (DUF3458_C) ARM repeats pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_16231_1 1234364.AMSF01000018_gene1411 3.2e-86 263.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_13478_1 1453503.AU05_21485 2.51e-35 124.0 2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1YGFT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 k141_21841_1 1234364.AMSF01000060_gene962 3.79e-19 81.6 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1X61V@135614|Xanthomonadales 135614|Xanthomonadales J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_21841_2 983545.Glaag_3693 1.47e-66 204.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,466SE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_5094_1 1247963.JPHU01000004_gene470 2.12e-14 69.3 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria 28211|Alphaproteobacteria I dehydratase nodN - - - - - - - - - - - MaoC_dehydratas k141_7920_1 686340.Metal_2699 2.34e-73 237.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XENA@135618|Methylococcales 135618|Methylococcales KLT kinase domain - - - - - - - - - - - - PP2C_2,Pkinase k141_14178_1 225937.HP15_1293 1.13e-44 154.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4647M@72275|Alteromonadaceae 1236|Gammaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_17661_1 340177.Cag_0763 1.33e-27 119.0 COG1330@1|root,COG1330@2|Bacteria,1FEMY@1090|Chlorobi 1090|Chlorobi L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma k141_17661_2 314282.PCNPT3_08710 6.93e-38 145.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,2QHY4@267894|Psychromonadaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_20482_1 391615.ABSJ01000034_gene1060 7.34e-85 256.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1J57Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_20482_2 2340.JV46_25830 5.25e-43 140.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1J6PJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k141_20482_3 291112.PAU_04370 9.29e-26 95.5 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k141_20482_4 765913.ThidrDRAFT_2125 1.38e-259 736.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_18359_1 7213.XP_004532022.1 8.99e-69 224.0 COG0028@1|root,KOG4166@2759|Eukaryota,3AEUK@33154|Opisthokonta 33154|Opisthokonta EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C k141_3731_1 1461694.ATO9_03165 3.09e-119 352.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2PD5M@252301|Oceanicola 28211|Alphaproteobacteria I Thiolase, C-terminal domain phbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_1629_1 298386.PBPRB0645 1.53e-86 274.0 COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria 1224|Proteobacteria C COG0348 Polyferredoxin vnfA - - - - - - - - - - - Fer4_5 k141_3027_1 1278309.KB907099_gene2792 2.69e-82 252.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1XJVX@135619|Oceanospirillales 135619|Oceanospirillales S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB k141_19086_1 396588.Tgr7_0948 1.84e-77 246.0 COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,1T20G@1236|Gammaproteobacteria 1236|Gammaproteobacteria EP PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_13479_1 1232683.ADIMK_0287 1.07e-57 186.0 COG1028@1|root,COG1028@2|Bacteria,1MW50@1224|Proteobacteria,1RRIH@1236|Gammaproteobacteria,469D8@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family benD - 1.3.1.25 ko:K05783 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113 RC00271,RC01326,RC01327 br01602,ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k141_14889_1 1026882.MAMP_01695 1.17e-14 76.6 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_14889_2 765914.ThisiDRAFT_2157 8.71e-47 167.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales 135613|Chromatiales CI TIGRFAM Oxaloacetate decarboxylase, alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_14895_3 1288826.MSNKSG1_04956 0.0 1148.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,464S3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_14895_4 1288826.MSNKSG1_04961 1.24e-209 581.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,464WJ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_14895_5 1288826.MSNKSG1_04966 1.02e-177 496.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,464K2@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_14895_6 1288826.MSNKSG1_04971 3.16e-198 550.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,465US@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_14895_7 1288826.MSNKSG1_04976 1.11e-187 521.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4663K@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1045 Serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0840 Hexapep,SATase_N k141_14895_8 1288826.MSNKSG1_04981 3.92e-113 325.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,466UA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_14895_9 1288826.MSNKSG1_04986 2.08e-264 725.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,4647T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 k141_14895_10 1288826.MSNKSG1_04991 8.03e-95 276.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,466Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_14895_11 1288826.MSNKSG1_04996 5.14e-268 733.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,46420@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_14895_12 1288826.MSNKSG1_05001 2.22e-146 416.0 COG3063@1|root,COG3063@2|Bacteria,1RAFJ@1224|Proteobacteria,1S5H6@1236|Gammaproteobacteria,467DR@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3063 Tfp pilus assembly protein PilF pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 k141_14895_13 1288826.MSNKSG1_05006 4.22e-61 196.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,4689I@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria rodZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_10729_1 1232683.ADIMK_1588 3.97e-26 98.6 COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SGS8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C oxaloacetate decarboxylase gamma chain oadG GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma k141_10729_2 1278309.KB907107_gene1764 3.05e-279 770.0 COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,1XHDX@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI k141_7204_1 1288826.MSNKSG1_18515 2.24e-294 810.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,465MX@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase pilS - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 k141_7204_2 1288826.MSNKSG1_18510 6.91e-312 852.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_7204_3 1288826.MSNKSG1_18505 3.23e-125 357.0 COG4970@1|root,COG4970@2|Bacteria,1QFYA@1224|Proteobacteria,1SDXQ@1236|Gammaproteobacteria,468F0@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4970 Tfp pilus assembly protein FimT fimT - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_7204_4 1288826.MSNKSG1_18500 1.22e-95 279.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_14193_1 2340.JV46_05620 6.98e-23 91.7 COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the thioredoxin family - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_19095_1 1288826.MSNKSG1_17621 5.36e-66 202.0 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,46885@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1664 Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin k141_19095_2 1288826.MSNKSG1_17616 8.24e-164 459.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19095_3 1288826.MSNKSG1_17611 6.25e-245 673.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,464RI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k141_19095_4 1288826.MSNKSG1_17606 0.0 1080.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,465J9@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0038 Chloride channel protein EriC eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_19095_5 1288826.MSNKSG1_17601 2.32e-29 107.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,467HW@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_6477_1 1094715.CM001373_gene2898 1.34e-44 155.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1JC72@118969|Legionellales 118969|Legionellales S HI0933-like protein yhiN - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_4460_1 571166.KI421509_gene3059 2.67e-53 173.0 COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_4460_2 1342302.JASC01000013_gene2609 3.62e-10 60.1 COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,3ZXBG@60136|Sulfitobacter 28211|Alphaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF2 - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B k141_12114_1 1124983.PFLCHA0_c07870 8.29e-53 169.0 COG0346@1|root,COG0346@2|Bacteria,1MZQY@1224|Proteobacteria,1T346@1236|Gammaproteobacteria,1YQDJ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E bleomycin resistance protein - - - - - - - - - - - - Glyoxalase k141_20503_1 929562.Emtol_2316 3.66e-89 287.0 COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_1652_1 396588.Tgr7_1564 1.96e-63 205.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1WW48@135613|Chromatiales 135613|Chromatiales H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_21861_1 472759.Nhal_0343 1.85e-57 183.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1WXYG@135613|Chromatiales 135613|Chromatiales Q PFAM Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_21861_2 1122603.ATVI01000011_gene2069 1.41e-26 108.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1X73J@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents auxiliary component - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_21861_3 1198232.CYCME_0824 5.77e-05 45.1 COG3113@1|root,COG3113@2|Bacteria,1QHCH@1224|Proteobacteria,1TEZ8@1236|Gammaproteobacteria,463DS@72273|Thiotrichales 72273|Thiotrichales S STAS domain - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 k141_19744_1 1192124.LIG30_2230 2.25e-21 93.6 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1K0BN@119060|Burkholderiaceae 28216|Betaproteobacteria P Ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_19744_3 1397666.RS24_01861 3e-36 132.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria 1224|Proteobacteria S TIGRFAM conserved - - - - - - - - - - - - Gcw_chp k141_7205_1 1168065.DOK_01639 3.12e-41 156.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1J5C9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_6478_1 1469245.JFBG01000056_gene2484 6.68e-68 216.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1WWKN@135613|Chromatiales 135613|Chromatiales C C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - k141_5101_1 1288826.MSNKSG1_14717 1.51e-54 187.0 COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,1RQ7B@1236|Gammaproteobacteria,464G6@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases - - 3.6.4.12 ko:K10844 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - DEAD_2,Helicase_C_2 k141_5101_2 1288826.MSNKSG1_14722 1.48e-310 845.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,464H4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442,Pyr_redox_2 k141_5101_3 1288826.MSNKSG1_14727 1.24e-203 565.0 COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the carbamate kinase family arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - iE2348C_1286.E2348C_0454,iECED1_1282.ECED1_0540,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iJN746.PP_0999 AA_kinase k141_5101_4 1288826.MSNKSG1_14732 3.59e-238 655.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,465TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argI GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 ko:K00611,ko:K09065 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410 OTCace,OTCace_N k141_5101_5 1288826.MSNKSG1_14737 2.17e-307 836.0 COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,1RM99@1236|Gammaproteobacteria,46A3D@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2235 Arginine deiminase arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf k141_5101_6 1288826.MSNKSG1_14742 0.0 902.0 COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,1RS2M@1236|Gammaproteobacteria,4657Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DcuC k141_5101_7 1288826.MSNKSG1_14792 3.25e-282 776.0 COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,1RR24@1236|Gammaproteobacteria,46764@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0168 Trk-type K transport systems, membrane components ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_5101_8 1288826.MSNKSG1_14797 4.61e-143 405.0 COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,1S6QA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0569 K transport systems NAD-binding component ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_5101_9 1288826.MSNKSG1_14802 0.0 899.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,46681@72275|Alteromonadaceae 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_5101_10 1288826.MSNKSG1_14807 0.0 1314.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,464RV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 DALR_1,tRNA_synt_2f k141_5101_11 1288826.MSNKSG1_14812 9.31e-250 685.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,4640E@72275|Alteromonadaceae 1236|Gammaproteobacteria J glycyl-tRNA synthetase alpha subunit glyQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF1260.b3560,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 tRNA-synt_2e k141_5101_12 1288826.MSNKSG1_14817 0.0 902.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,464GU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0569 K transport systems, NAD-binding component trkA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iE2348C_1286.E2348C_3552 TrkA_C,TrkA_N k141_5101_13 1288826.MSNKSG1_14822 2.3e-215 600.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,465KP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_227_1 1288826.MSNKSG1_10188 5.9e-88 258.0 COG3232@1|root,COG3232@2|Bacteria,1RB8A@1224|Proteobacteria,1S3SG@1236|Gammaproteobacteria,46DMS@72275|Alteromonadaceae 1236|Gammaproteobacteria E 5-carboxymethyl-2-hydroxymuconate isomerase hpcD - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_4572,iECO103_1326.ECO103_5133,iEKO11_1354.EKO11_3963,iEcHS_1320.EcHS_A4581,iSBO_1134.SBO_4409,iSbBS512_1146.SbBS512_E4887 CHMI k141_227_2 1288826.MSNKSG1_10183 5.11e-191 533.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria,46AIM@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_20504_1 1122212.AULO01000009_gene934 7.85e-41 150.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,1XIYN@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_12115_1 998674.ATTE01000001_gene2455 1.14e-47 166.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_12115_2 580332.Slit_2585 0.000762 42.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,44VS6@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_228_1 396588.Tgr7_0226 1.88e-74 239.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_5102_1 1231185.BAMP01000043_gene1152 4.12e-23 94.4 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,43JVJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the UPF0260 family MA20_15575 - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_5102_2 1401065.HMPREF2130_05925 1.39e-26 102.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,2VU8X@28216|Betaproteobacteria,3T4T4@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function (DUF423) ygdD - - - - - - - - - - - DUF423 k141_14899_1 1121104.AQXH01000015_gene1 2.66e-67 217.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1IQVK@117747|Sphingobacteriia 976|Bacteroidetes CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_3046_1 521719.ATXQ01000005_gene1451 3.89e-33 130.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1YCTA@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_3046_2 187272.Mlg_1231 5.13e-136 393.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_19096_1 1278309.KB907099_gene2671 8.49e-62 198.0 COG4977@1|root,COG4977@2|Bacteria,1RC9C@1224|Proteobacteria,1RYDT@1236|Gammaproteobacteria,1XJA4@135619|Oceanospirillales 135619|Oceanospirillales K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_19096_2 1122599.AUGR01000010_gene1055 7.07e-162 464.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIMQ@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid betB - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_1653_1 1121935.AQXX01000142_gene2326 1.38e-84 271.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_1653_2 203122.Sde_2263 6.77e-23 94.4 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,467DP@72275|Alteromonadaceae 1236|Gammaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_2491_1 1278309.KB907100_gene2297 5.8e-07 50.1 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales 135619|Oceanospirillales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_2491_2 1278309.KB907100_gene2296 3.96e-99 303.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XHGY@135619|Oceanospirillales 135619|Oceanospirillales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_11564_1 393595.ABO_1892 1.08e-76 257.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1XID1@135619|Oceanospirillales 135619|Oceanospirillales EI carboxylase uahA - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_11564_2 396588.Tgr7_3090 1.27e-206 594.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1WXE4@135613|Chromatiales 135613|Chromatiales J Allophanate hydrolase - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_1819_1 1288826.MSNKSG1_00026 4.02e-248 688.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,4641Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_1819_2 1288826.MSNKSG1_00031 1.23e-169 475.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,46719@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0084 Mg-dependent DNase yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_1134_2 365046.Rta_37360 1.64e-51 171.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,4AA3Q@80864|Comamonadaceae 28216|Betaproteobacteria S cAMP phosphodiesterases class-II - - 3.1.4.17 ko:K01120 ko00230,map00230 - R00191,R01234 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 k141_15779_1 314264.ROS217_23092 1.22e-74 238.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2U2FB@28211|Alphaproteobacteria,46Q68@74030|Roseovarius 28211|Alphaproteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) - - - - - - - - - - - - DAO k141_12296_1 398580.Dshi_1652 2.41e-112 335.0 COG1653@1|root,COG1653@2|Bacteria,1MXZJ@1224|Proteobacteria,2TSFY@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC-type sugar transport system periplasmic component aglE - - ko:K10232 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - SBP_bac_1,SBP_bac_8 k141_8758_1 1121920.AUAU01000004_gene605 1.43e-67 217.0 COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria 57723|Acidobacteria E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_21354_2 34506.g6044 1.49e-54 192.0 COG0024@1|root,COG0180@1|root,COG0590@1|root,KOG0254@1|root,KOG0254@2759|Eukaryota,KOG1018@2759|Eukaryota,KOG2713@2759|Eukaryota,KOG2738@2759|Eukaryota,38WFQ@33154|Opisthokonta,3C6TZ@33208|Metazoa,3DD7G@33213|Bilateria,40K4U@6231|Nematoda,1M3HK@119089|Chromadorea,41615@6236|Rhabditida 33208|Metazoa O Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 k141_21354_3 1123401.JHYQ01000026_gene3246 2.41e-65 222.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MX4H@1224|Proteobacteria,1RRJV@1236|Gammaproteobacteria,461X2@72273|Thiotrichales 72273|Thiotrichales P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_8149_1 396588.Tgr7_2031 2.64e-47 161.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1WVZF@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_17118_1 269796.Rru_A3658 4.46e-49 176.0 COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2TU8I@28211|Alphaproteobacteria,2JQNW@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1 k141_12994_1 318167.Sfri_2065 0.000225 42.7 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S0DD@1236|Gammaproteobacteria,2QCYF@267890|Shewanellaceae 1236|Gammaproteobacteria I PFAM MaoC domain protein dehydratase nodN - - - - - - - - - - - MaoC_dehydratas k141_2492_2 243233.MCA1095 3.99e-31 116.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1XDW2@135618|Methylococcales 135618|Methylococcales S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_14311_1 861208.AGROH133_09856 2.6e-30 112.0 COG2246@1|root,COG2246@2|Bacteria,1NA3W@1224|Proteobacteria 1224|Proteobacteria S PFAM GtrA family protein - - - - - - - - - - - - GtrA k141_14311_2 1123073.KB899241_gene2078 5.52e-27 109.0 COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,1S0R5@1236|Gammaproteobacteria,1X5SI@135614|Xanthomonadales 135614|Xanthomonadales H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase k141_19286_1 314278.NB231_17273 3.48e-17 85.9 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_431_1 857087.Metme_3216 8.35e-56 188.0 COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,1RR54@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_431_3 472759.Nhal_2221 2.97e-20 89.4 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria,1X055@135613|Chromatiales 135613|Chromatiales F PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_3241_1 1249627.D779_0916 7.22e-119 361.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_11565_1 472759.Nhal_0879 1.49e-72 228.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1WXJR@135613|Chromatiales 135613|Chromatiales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_5300_1 1305735.JAFT01000005_gene2454 2.84e-48 172.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria,2PCTP@252301|Oceanicola 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_5300_2 1192124.LIG30_3676 5.29e-99 298.0 COG1028@1|root,COG1028@2|Bacteria,1MX6D@1224|Proteobacteria,2VM63@28216|Betaproteobacteria,1K3DT@119060|Burkholderiaceae 28216|Betaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_5300_3 1122201.AUAZ01000001_gene2405 2.14e-161 470.0 COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,1RNYN@1236|Gammaproteobacteria,469TH@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase - - 1.3.99.4 ko:K05898 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R09884 RC00991 ko00000,ko00001,ko01000 - - - FAD_binding_2 k141_7378_1 1123400.KB904747_gene617 2.27e-79 264.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales 72273|Thiotrichales L ATP-dependent helicase hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_1820_1 1500893.JQNB01000001_gene738 5.52e-22 89.7 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1X6DJ@135614|Xanthomonadales 135614|Xanthomonadales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_1820_2 1500893.JQNB01000001_gene737 5.68e-110 330.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1X31U@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_21355_1 1231392.OCGS_1269 1.04e-80 249.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Pilus assembly protein - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF k141_21355_2 633131.TR2A62_1888 2.71e-06 50.4 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU type II secretion system protein - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_17866_1 1415779.JOMH01000001_gene1020 5.36e-15 76.6 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1X665@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_17866_2 243365.CV_3695 8.53e-182 513.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,2KQFE@206351|Neisseriales 206351|Neisseriales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_4620_1 225849.swp_3299 5.78e-07 51.2 COG0564@1|root,COG0564@2|Bacteria,1R4IN@1224|Proteobacteria,1S0WR@1236|Gammaproteobacteria,2QAW1@267890|Shewanellaceae 1236|Gammaproteobacteria J PFAM pseudouridine synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_10902_1 446471.Xcel_2090 1.9e-26 107.0 COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4F4FG@85017|Promicromonosporaceae 201174|Actinobacteria L RecQ zinc-binding recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k141_10902_2 1122201.AUAZ01000001_gene2224 2.27e-105 323.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,465ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2206 HD-GYP domain - - - - - - - - - - - - DUF3391,HD,HD_5 k141_2493_1 1461693.ATO10_06071 8.22e-54 180.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidylprolyl isomerase ppiC - 5.2.1.8 ko:K01802,ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_15780_1 1278309.KB907103_gene1018 3.89e-30 112.0 2CAI4@1|root,33JPF@2|Bacteria,1NP1T@1224|Proteobacteria,1SY6Z@1236|Gammaproteobacteria,1XQGG@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15780_2 1278309.KB907103_gene1017 1.86e-71 216.0 COG2030@1|root,COG2030@2|Bacteria,1RCCM@1224|Proteobacteria,1S39P@1236|Gammaproteobacteria,1XJN4@135619|Oceanospirillales 135619|Oceanospirillales I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas k141_22027_1 396588.Tgr7_1844 2.75e-117 362.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WW6D@135613|Chromatiales 135613|Chromatiales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_22027_3 396588.Tgr7_1849 3.78e-145 422.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1WW57@135613|Chromatiales 135613|Chromatiales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_11566_1 305900.GV64_06035 1.13e-30 117.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XHEV@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_11566_2 1401065.HMPREF2130_09230 1.75e-08 55.5 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,3T1E7@506|Alcaligenaceae 28216|Betaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_1155_1 697282.Mettu_2182 1.43e-34 125.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XEWA@135618|Methylococcales 135618|Methylococcales O Thiol disulfide interchange protein dsbA - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA k141_1155_2 1026882.MAMP_00725 3.14e-188 537.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales 72273|Thiotrichales EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_10920_1 1278309.KB907099_gene2601 1.03e-98 301.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XIJJ@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_6657_1 396588.Tgr7_0799 3.27e-65 213.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1WXAG@135613|Chromatiales 135613|Chromatiales E PFAM sodium alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_22040_1 768706.Desor_0428 2.9e-22 108.0 COG0823@1|root,COG2247@1|root,COG0823@2|Bacteria,COG2247@2|Bacteria 2|Bacteria M cell wall organization - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - CW_binding_2,CarboxypepD_reg,Flg_new,NHL,PD40,Peptidase_S8,TIG,VCBS k141_3885_1 561229.Dd1591_1063 4.73e-09 61.6 COG3073@1|root,COG3073@2|Bacteria,1R4U0@1224|Proteobacteria,1RN98@1236|Gammaproteobacteria,2JCP4@204037|Dickeya 1236|Gammaproteobacteria T An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E rseA GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - ko:K03597 - - - - ko00000,ko03021 - - - RseA_C,RseA_N k141_11577_1 153721.MYP_1856 2.47e-55 196.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia 976|Bacteroidetes E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_15049_1 716544.wcw_1628 2.98e-122 360.0 COG0686@1|root,COG0686@2|Bacteria,2JFCH@204428|Chlamydiae 204428|Chlamydiae C Alanine dehydrogenase/PNT, N-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_13012_1 1278309.KB907105_gene1402 2.42e-55 182.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XHU3@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_13012_2 1278309.KB907105_gene1401 1.43e-75 238.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XHBS@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_12320_1 1288826.MSNKSG1_09138 9.89e-238 653.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,464W4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1702 Phosphate starvation-inducible protein PhoH ybeZ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06217 - - - - ko00000 - - - PhoH k141_13697_1 1232683.ADIMK_2338 4.89e-49 159.0 28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S49D@1236|Gammaproteobacteria,469ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7399_1 1049564.TevJSym_ba00030 6.33e-212 622.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1J4NP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase III, alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_447_1 926559.JoomaDRAFT_3556 8.37e-08 61.2 COG1361@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,1IKB7@117743|Flavobacteriia 976|Bacteroidetes M Domain of unknown function DUF11 - - - - - - - - - - - - CHU_C,Cu-binding_MopE,DUF11,HYR,Laminin_G_3,PKD,SprB k141_447_2 1232410.KI421421_gene3532 2.83e-53 181.0 COG4719@1|root,COG4719@2|Bacteria,1RARY@1224|Proteobacteria,42UYT@68525|delta/epsilon subdivisions,2WQ3G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11 k141_15805_1 312309.VF_0460 7.53e-69 219.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XUA4@135623|Vibrionales 135623|Vibrionales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_1156_1 1057002.KB905370_gene4580 4.04e-07 53.9 COG2303@1|root,COG2303@2|Bacteria,1MUK2@1224|Proteobacteria,2U08V@28211|Alphaproteobacteria,4BBVU@82115|Rhizobiaceae 28211|Alphaproteobacteria E GMC oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k141_1156_2 247639.MGP2080_12673 2.46e-22 95.5 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q hydratase hpaH - 4.1.1.77 ko:K01617,ko:K02509 ko00350,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00350,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R04132,R05374,R06897 RC00751,RC01615,RC02595,RC02672 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_4571,iYL1228.KPN_04784 FAA_hydrolase k141_5323_1 1286106.MPL1_06779 1.93e-34 138.0 COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria 1236|Gammaproteobacteria P transport system, permease component pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_21379_1 911045.PSE_3737 1.07e-31 134.0 COG1289@1|root,COG1289@2|Bacteria 2|Bacteria S transmembrane transporter activity VPA1578 - - - - - - - - - - - FUSC k141_19921_1 754477.Q7C_1914 1.03e-155 450.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales 72273|Thiotrichales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_19921_2 1335757.SPICUR_09505 4.72e-08 53.1 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales 135613|Chromatiales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP k141_13698_1 1116472.MGMO_36c00020 2.68e-07 48.5 COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,1S9AZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - ThiS k141_13698_2 207954.MED92_15053 4.46e-90 274.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XMZH@135619|Oceanospirillales 135619|Oceanospirillales P Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_15806_1 1122614.JHZF01000013_gene4171 4.21e-34 123.0 COG4121@1|root,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2TUNX@28211|Alphaproteobacteria,2PE0E@252301|Oceanicola 28211|Alphaproteobacteria J S-adenosyl-L-methionine-dependent methyltransferase mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_15806_2 1353537.TP2_03530 1.44e-16 79.0 COG0665@1|root,COG0665@2|Bacteria,1MUUJ@1224|Proteobacteria,2TR9J@28211|Alphaproteobacteria,2XMUN@285107|Thioclava 28211|Alphaproteobacteria E FAD dependent oxidoreductase goxB - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_3260_1 1288826.MSNKSG1_16951 1.06e-99 310.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,464NC@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2183 Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_3260_2 1288826.MSNKSG1_16946 1.74e-125 372.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,469T1@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_16433_1 1288826.MSNKSG1_10228 1.77e-195 550.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RRYY@1236|Gammaproteobacteria,469F2@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Transmembrane secretion effector bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr k141_1305_2 553178.CAPGI0001_1065 5.89e-65 209.0 COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1HX0F@117743|Flavobacteriia,1EQ8N@1016|Capnocytophaga 976|Bacteroidetes O Psort location Cytoplasmic, score 8.96 prtC - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 k141_9564_1 998674.ATTE01000001_gene1721 6.52e-103 323.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales 72273|Thiotrichales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_1962_1 1278309.KB907100_gene2031 1.81e-126 361.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,1XJH8@135619|Oceanospirillales 135619|Oceanospirillales L Uracil-DNA glycosylase - - - - - - - - - - - - UDG k141_1962_2 1278309.KB907100_gene2032 1.37e-204 577.0 2C7MP@1|root,2Z7Q4@2|Bacteria,1NHK1@1224|Proteobacteria,1RQ17@1236|Gammaproteobacteria,1XJDF@135619|Oceanospirillales 135619|Oceanospirillales S Methyltransferase domain - - - - - - - - - - - - Methyltransf_32 k141_1962_3 1278309.KB907100_gene2033 2.29e-57 184.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1XJEC@135619|Oceanospirillales 135619|Oceanospirillales S Ser threonine protein phosphatase - - - - - - - - - - - - Metallophos,Metallophos_2 k141_17284_1 314260.PB2503_10484 1.02e-30 120.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UG3A@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k141_21511_2 1121374.KB891575_gene878 8.32e-23 97.1 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_16579_1 1131269.AQVV01000015_gene2023 7.85e-35 139.0 28HH1@1|root,2Z7SS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_1306_1 1163408.UU9_14865 2.81e-97 290.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1XBWP@135614|Xanthomonadales 135614|Xanthomonadales T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_20747_1 244582.JQAK01000010_gene2473 5.28e-64 209.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U28T@28211|Alphaproteobacteria,47F3F@766|Rickettsiales 766|Rickettsiales L Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - GIIM,RVT_1 k141_9565_1 1469613.JT55_03500 3.12e-46 162.0 COG1664@1|root,COG1664@2|Bacteria,1MUS9@1224|Proteobacteria,2TSAA@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_13845_2 2340.JV46_02580 1.03e-78 246.0 COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,1S76Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_15941_1 472759.Nhal_0530 9.43e-97 310.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales 135613|Chromatiales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_17285_1 1278309.KB907105_gene1492 1.15e-84 275.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XH2S@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_6122_2 760117.JN27_10955 8.89e-11 66.6 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VMHQ@28216|Betaproteobacteria,477SF@75682|Oxalobacteraceae 28216|Betaproteobacteria O Subtilase family - - 3.4.21.66 ko:K08651,ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k141_1307_1 768671.ThimaDRAFT_1230 6.34e-40 145.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1WX5T@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_15163_4 1288826.MSNKSG1_09853 2.03e-175 490.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria,4665I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_15163_5 1288826.MSNKSG1_09858 1.44e-254 713.0 COG0840@1|root,COG0840@2|Bacteria,1RFSF@1224|Proteobacteria,1S42G@1236|Gammaproteobacteria,46AWM@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_21533_1 1178482.BJB45_07150 4.41e-36 130.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XHRF@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter, ATP-binding protein - - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_21533_2 998674.ATTE01000001_gene4478 1.46e-36 133.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,460GX@72273|Thiotrichales 72273|Thiotrichales E branched-chain amino acid transport system, permease component - - - ko:K11961 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_14462_1 425104.Ssed_2174 1.39e-139 410.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,2Q9PS@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_11717_1 1286106.MPL1_07388 1.43e-81 263.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,460AS@72273|Thiotrichales 72273|Thiotrichales C radical SAM protein YgiQ - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_13186_1 1122134.KB893651_gene1961 1.15e-110 327.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XHU3@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_3410_1 439235.Dalk_2155 3.25e-12 76.6 COG2931@1|root,COG2931@2|Bacteria,1R094@1224|Proteobacteria 1224|Proteobacteria Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - UnbV_ASPIC,VCBS k141_1325_1 697282.Mettu_3162 5.96e-46 170.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_21534_1 1120953.AUBH01000005_gene2485 4.1e-77 246.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18083_1 1085623.GNIT_2918 1.95e-20 91.7 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_18083_2 1178482.BJB45_03070 9.72e-75 228.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1XJPI@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB k141_6129_1 1122197.ATWI01000010_gene951 3.61e-204 584.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,46428@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG2202 FOG PAS PAC domain - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_6129_2 225937.HP15_3727 2.17e-133 397.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RXC9@1236|Gammaproteobacteria,46CHD@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS domain - - - - - - - - - - - - GGDEF,PAS_3 k141_6129_3 1288826.MSNKSG1_15861 1.02e-92 278.0 COG5001@1|root,COG5001@2|Bacteria 2|Bacteria T cyclic-guanylate-specific phosphodiesterase activity - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_6129_4 1288826.MSNKSG1_15856 3.7e-56 178.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3,HTH_31 k141_6129_5 1288826.MSNKSG1_15851 1.46e-260 715.0 COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,1S4PZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - DUF3391,HD_5 k141_6129_6 1288826.MSNKSG1_15846 1.59e-208 575.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,46528@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde fghA - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase k141_6129_7 1288826.MSNKSG1_15841 4.28e-100 290.0 COG0517@1|root,COG0517@2|Bacteria,1N2TU@1224|Proteobacteria,1S9T1@1236|Gammaproteobacteria,468HW@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_6129_8 1288826.MSNKSG1_15836 2.8e-310 847.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter dagA - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_6129_9 1288826.MSNKSG1_15831 9.51e-160 447.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,1RPQV@1236|Gammaproteobacteria,464G1@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peroxiredoxin lsfA - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA k141_6129_10 1288826.MSNKSG1_15826 4.81e-180 502.0 COG1464@1|root,COG1464@2|Bacteria,1MUVY@1224|Proteobacteria,1RS3R@1236|Gammaproteobacteria,46AZC@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen metQ-2 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 k141_6129_11 1288826.MSNKSG1_15821 6.01e-140 397.0 COG2011@1|root,COG2011@2|Bacteria,1MW8E@1224|Proteobacteria,1RPKY@1236|Gammaproteobacteria,46AW3@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2011 ABC-type metal ion transport system, permease component metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 k141_6129_12 1288826.MSNKSG1_15816 3.3e-235 647.0 COG1135@1|root,COG1135@2|Bacteria,1QTTK@1224|Proteobacteria,1RMQD@1236|Gammaproteobacteria,469M4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL k141_6129_13 1288826.MSNKSG1_15811 0.0 881.0 COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria,468NW@72275|Alteromonadaceae 1236|Gammaproteobacteria T HDOD domain - - - - - - - - - - - - GAF,GAF_3,HDOD,Pkinase k141_6129_14 1288826.MSNKSG1_15806 4.29e-159 446.0 COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,1SAB3@1236|Gammaproteobacteria,467FT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - RskA k141_6129_15 1288826.MSNKSG1_15801 8.61e-130 369.0 COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,1S90I@1236|Gammaproteobacteria,4675I@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigK - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_6129_16 1288826.MSNKSG1_15796 0.0 964.0 2DB7W@1|root,2Z7P1@2|Bacteria,1N65F@1224|Proteobacteria,1RQEC@1236|Gammaproteobacteria,464P7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4331) - - - - - - - - - - - - DUF4331 k141_6129_18 1288826.MSNKSG1_15786 3.31e-247 682.0 COG0457@1|root,COG0457@2|Bacteria,1RAPH@1224|Proteobacteria,1S590@1236|Gammaproteobacteria,4683I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19 k141_6129_19 1288826.MSNKSG1_15781 2.38e-56 185.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,466KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_7563_1 1123399.AQVE01000001_gene564 2.8e-166 483.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,460E6@72273|Thiotrichales 72273|Thiotrichales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_9586_1 765911.Thivi_2321 1.02e-127 383.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_1979_1 497321.C664_06748 1.85e-87 265.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,2KUMP@206389|Rhodocyclales 206389|Rhodocyclales S COG0714 MoxR-like ATPases norQ - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_1979_2 1049564.TevJSym_bg00280 7.7e-43 144.0 2C0CP@1|root,32SP5@2|Bacteria,1N5DU@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_1979_3 2340.JV46_05470 9.58e-11 62.8 COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_5 k141_590_1 1288826.MSNKSG1_10928 1.69e-249 695.0 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - COX2,Cupredoxin_1 k141_590_2 1288826.MSNKSG1_10923 7.67e-290 793.0 COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Nitrous oxidase accessory protein nosD - - ko:K07218 - - - - ko00000 - - - NosD k141_590_3 1288826.MSNKSG1_10918 5.99e-214 592.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RY6M@1236|Gammaproteobacteria,46AJC@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities nosF - - ko:K19340 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC_tran k141_590_4 1288826.MSNKSG1_10913 5.75e-179 500.0 COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,1RQFG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component nosY - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2 k141_590_5 1288826.MSNKSG1_10908 1.06e-109 318.0 COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,1S7G3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NosL protein nosL - - ko:K19342 - - - - ko00000 - - - NosL k141_590_6 1288826.MSNKSG1_10898 7.27e-241 661.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,464NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_590_7 1288826.MSNKSG1_10893 0.0 1048.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,464BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3256 Nitric oxide reductase large subunit norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_5496_2 1123368.AUIS01000013_gene872 5.88e-46 150.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,2ND3N@225057|Acidithiobacillales 225057|Acidithiobacillales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 k141_5496_3 998088.B565_0195 2.23e-99 291.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1Y3QD@135624|Aeromonadales 135624|Aeromonadales J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_5496_5 870187.Thini_3326 7.3e-34 120.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,460S8@72273|Thiotrichales 72273|Thiotrichales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_13187_1 1121413.JMKT01000011_gene2355 9.34e-09 56.2 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2M7Y4@213115|Desulfovibrionales 28221|Deltaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_13187_2 391615.ABSJ01000033_gene696 1.24e-96 291.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1J56G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_14463_1 349521.HCH_02594 6.62e-70 239.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1XNC8@135619|Oceanospirillales 135619|Oceanospirillales U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_11083_1 1123504.JQKD01000117_gene390 1.22e-89 284.0 COG1120@1|root,COG2453@1|root,COG1120@2|Bacteria,COG2453@2|Bacteria,1P0GN@1224|Proteobacteria,2VNDH@28216|Betaproteobacteria,4AC63@80864|Comamonadaceae 28216|Betaproteobacteria HPT PFAM Dual specificity protein phosphatase - - 3.1.3.16,3.1.3.48 ko:K14165 - - - - ko00000,ko01000,ko01009 - - - ABC_tran,DSPc k141_2662_1 1260251.SPISAL_02805 2.27e-105 320.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales 135613|Chromatiales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k141_2662_2 1121921.KB898709_gene244 2.27e-51 167.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,2PNF2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Ribosomal protein L9, N-terminal domain rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_6779_1 1049564.TevJSym_bm00140 5.58e-49 162.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1J656@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325 CDP-OH_P_transf k141_6779_2 1286106.MPL1_08639 2.36e-111 339.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,45ZPV@72273|Thiotrichales 72273|Thiotrichales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_4005_1 491952.Mar181_1006 2.16e-185 523.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1XS5V@135619|Oceanospirillales 135619|Oceanospirillales P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_8887_1 1288826.MSNKSG1_05146 2.32e-173 483.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,4658G@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Fer2_3,Fer4_17,Fer4_8 k141_8887_2 1288826.MSNKSG1_05141 0.0 1174.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,4646I@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111 FAD_binding_2,Succ_DH_flav_C k141_8887_3 1288826.MSNKSG1_05136 3.47e-78 232.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,467WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Membrane-anchoring subunit of succinate dehydrogenase (SDH) sdhD GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - e_coli_core.b0722,iAF1260.b0722,iAPECO1_1312.APECO1_1356,iB21_1397.B21_00671,iBWG_1329.BWG_0581,iE2348C_1286.E2348C_0602,iEC042_1314.EC042_0740,iECABU_c1320.ECABU_c07680,iECBD_1354.ECBD_2938,iECB_1328.ECB_00682,iECDH10B_1368.ECDH10B_0789,iECDH1ME8569_1439.ECDH1ME8569_0681,iECD_1391.ECD_00682,iECED1_1282.ECED1_0692,iECIAI1_1343.ECIAI1_0696,iECIAI39_1322.ECIAI39_0680,iECNA114_1301.ECNA114_0658,iECO103_1326.ECO103_0716,iECO111_1330.ECO111_0739,iECO26_1355.ECO26_0783,iECOK1_1307.ECOK1_0722,iECP_1309.ECP_0734,iECS88_1305.ECS88_0748,iECSE_1348.ECSE_0782,iECSF_1327.ECSF_0655,iECUMN_1333.ECUMN_0800,iECW_1372.ECW_m0777,iEKO11_1354.EKO11_3157,iETEC_1333.ETEC_0733,iEcDH1_1363.EcDH1_2913,iEcE24377_1341.EcE24377A_0749,iEcHS_1320.EcHS_A0770,iEcSMS35_1347.EcSMS35_0735,iEcolC_1368.EcolC_2933,iJO1366.b0722,iJR904.b0722,iLF82_1304.LF82_2100,iNRG857_1313.NRG857_03215,iSBO_1134.SBO_0580,iSDY_1059.SDY_0660,iSFV_1184.SFV_0613,iSF_1195.SF0575,iSFxv_1172.SFxv_0634,iSSON_1240.SSON_0673,iS_1188.S0588,iUMN146_1321.UM146_14010,iUMNK88_1353.UMNK88_758,iUTI89_1310.UTI89_C0718,iWFL_1372.ECW_m0777,iY75_1357.Y75_RS03755,ic_1306.c0800 Sdh_cyt k141_8887_4 443152.MDG893_08030 1.04e-83 250.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,467R9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_8887_5 1288826.MSNKSG1_05126 1.96e-316 860.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,464XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the citrate synthase family gltA GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_00727 Citrate_synt k141_8887_6 1288826.MSNKSG1_05121 5.39e-307 839.0 COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,1RNDR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - Erythro_esteras,PCMT k141_8887_7 1318628.MARLIPOL_06949 3.46e-209 587.0 COG0501@1|root,COG0501@2|Bacteria,1R47C@1224|Proteobacteria,1RPRU@1236|Gammaproteobacteria,46BJ5@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48,Pilin k141_18727_1 1380358.JADJ01000004_gene1885 3.6e-61 203.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1XN1F@135619|Oceanospirillales 135619|Oceanospirillales E the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_18727_2 207954.MED92_02529 3.7e-70 219.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R6D0@1224|Proteobacteria,1S1VT@1236|Gammaproteobacteria,1XREX@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_18727_4 1124983.PFLCHA0_c34980 3.6e-07 52.4 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_1327_1 1211114.ALIP01000081_gene2506 1.59e-79 255.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_15165_1 266779.Meso_0450 6.24e-27 108.0 COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2TR6B@28211|Alphaproteobacteria,43HZH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_15165_2 402626.Rpic_4108 1.04e-07 54.7 COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2VM9G@28216|Betaproteobacteria,1KG5Q@119060|Burkholderiaceae 28216|Betaproteobacteria I Alpha beta hydrolase pepIP - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 k141_18084_1 1411685.U062_00149 6.13e-14 70.9 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1J54Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_18084_2 326297.Sama_1989 3.93e-17 80.9 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,2Q9K1@267890|Shewanellaceae 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - PNPase_C,RNase_E_G,S1 k141_11084_1 522306.CAP2UW1_3282 1.73e-41 154.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF,GAF_2,GAF_3,HATPase_c k141_3411_1 1278309.KB907102_gene186 1.37e-118 351.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XIX4@135619|Oceanospirillales 135619|Oceanospirillales T Bacterial regulatory protein, Fis family - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_3411_2 1278309.KB907102_gene187 4.36e-98 294.0 COG2358@1|root,COG2358@2|Bacteria,1NSTZ@1224|Proteobacteria,1RP8B@1236|Gammaproteobacteria,1XHFZ@135619|Oceanospirillales 135619|Oceanospirillales S C4-dicarboxylate ABC transporter substrate-binding protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_6311_1 1278309.KB907102_gene48 1.64e-51 166.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XI6S@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_6311_2 1278309.KB907102_gene47 1.73e-90 268.0 COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1XK5U@135619|Oceanospirillales 135619|Oceanospirillales S periplasmic or secreted lipoprotein - - - - - - - - - - - - BON k141_11899_1 349102.Rsph17025_2154 1.7e-55 182.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,1FBHF@1060|Rhodobacter 28211|Alphaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_5640_1 1049564.TevJSym_bc00170 5.75e-119 351.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1J5M1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Ketoacyl-synt_C,ketoacyl-synt k141_20992_1 1454202.PPBDW_90291___1 4.8e-19 90.1 COG1289@1|root,COG1289@2|Bacteria,1QJE4@1224|Proteobacteria,1THDF@1236|Gammaproteobacteria,1XU9P@135623|Vibrionales 135623|Vibrionales S Aromatic acid exporter family member 1 - - - - - - - - - - - - FUSC k141_7733_1 1179773.BN6_49070 3.63e-20 90.9 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding - - - - - - - - - - - - CxxCxxCC k141_7733_2 587753.EY04_08520 1.36e-106 321.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Xanthine and CO dehydrogenases maturation factor XdhC CoxF family xdhC2 - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_7733_3 1123399.AQVE01000011_gene1229 2.62e-09 58.2 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1SCSV@1236|Gammaproteobacteria,462UB@72273|Thiotrichales 72273|Thiotrichales S MobA-like NTP transferase domain - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_20275_1 1298593.TOL_2287 3.77e-38 139.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XIP7@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_20275_2 187272.Mlg_0928 2.26e-18 82.8 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,1WW2D@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH k141_3535_1 391616.OA238_c15640 1.67e-54 184.0 COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2U6FI@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K10544 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - BPD_transp_2 k141_5641_1 1112216.JH594426_gene3799 1.77e-55 189.0 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2K2UN@204457|Sphingomonadales 204457|Sphingomonadales L Integrase core domain - - - - - - - - - - - - rve k141_4925_1 768706.Desor_0813 1.4e-66 221.0 COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes,25ECT@186801|Clostridia,267FU@186807|Peptococcaceae 186801|Clostridia U TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_11229_1 1249627.D779_0302 2.34e-94 287.0 COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales 135613|Chromatiales Q Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD k141_11229_2 1255043.TVNIR_0863 4.3e-22 87.0 2E3CD@1|root,32YBP@2|Bacteria,1N8PD@1224|Proteobacteria,1SCSK@1236|Gammaproteobacteria,1WZ7C@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_11229_3 396588.Tgr7_2182 7.43e-64 205.0 2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria,1WW2H@135613|Chromatiales 135613|Chromatiales S TIGRFAM CRISPR-associated protein - - - - - - - - - - - - Cas6 k141_11229_4 870187.Thini_3762 7.67e-50 160.0 COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria 1236|Gammaproteobacteria P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_7734_1 1197477.IA57_02000 5.25e-26 104.0 COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k141_20993_1 1278309.KB907104_gene817 1.83e-111 333.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1XH4E@135619|Oceanospirillales 135619|Oceanospirillales S type VI secretion protein - - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_20993_2 1278309.KB907104_gene816 1.42e-26 100.0 COG3516@1|root,COG3516@2|Bacteria,1RA8Z@1224|Proteobacteria,1S687@1236|Gammaproteobacteria,1XQZ7@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - - - - - - - - - - T6SS_VipA k141_4212_1 1380358.JADJ01000009_gene26 1.11e-56 190.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,1XIHH@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_4212_2 1232683.ADIMK_2280 6.61e-33 122.0 COG0010@1|root,COG0010@2|Bacteria,1NCRN@1224|Proteobacteria,1RNKI@1236|Gammaproteobacteria,464I8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.11,3.5.3.8 ko:K01479,ko:K01480 ko00330,ko00340,ko01100,map00330,map00340,map01100 M00045,M00133 R01157,R02285 RC00024,RC00221,RC00329,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_11230_1 768671.ThimaDRAFT_1032 6.08e-85 275.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_16077_1 349521.HCH_03207 0.0 967.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1XHQB@135619|Oceanospirillales 135619|Oceanospirillales P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_16077_2 641107.CDLVIII_0146 9.23e-16 74.7 COG1846@1|root,COG1846@2|Bacteria,1VA2C@1239|Firmicutes,24KKX@186801|Clostridia,36IBD@31979|Clostridiaceae 186801|Clostridia K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 k141_16779_1 221288.JH992901_gene785 6.91e-32 127.0 COG3344@1|root,COG3344@2|Bacteria,1GJUS@1117|Cyanobacteria,1JJRH@1189|Stigonemataceae 1117|Cyanobacteria L Type II intron maturase - - - - - - - - - - - - Intron_maturas2,RVT_1 k141_12608_1 1179155.CF67_03054 4.92e-35 132.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC2 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_12608_2 1159870.KB907784_gene2607 1.91e-08 55.8 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k141_20994_1 1437882.AZRU01000005_gene1421 2.93e-05 45.4 COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type molybdenum transport system ATPase component photorepair protein PhrA modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.34 ko:K02013,ko:K05776 ko02010,map02010 M00189,M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_20994_2 2340.JV46_11880 2.31e-58 186.0 COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,1J6M2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CH Flavodoxin domain hemG GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 ko:K00230 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R09489 RC00885 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3850,iAPECO1_1312.APECO1_2607,iB21_1397.B21_03690,iBWG_1329.BWG_3526,iE2348C_1286.E2348C_4162,iECABU_c1320.ECABU_c43520,iECBD_1354.ECBD_4175,iECB_1328.ECB_03741,iECDH10B_1368.ECDH10B_4039,iECDH1ME8569_1439.ECDH1ME8569_3727,iECD_1391.ECD_03741,iECED1_1282.ECED1_4552,iECH74115_1262.ECH74115_5289,iECIAI1_1343.ECIAI1_4043,iECNA114_1301.ECNA114_4159,iECOK1_1307.ECOK1_4319,iECS88_1305.ECS88_4298,iECSF_1327.ECSF_3707,iECSP_1301.ECSP_4903,iECs_1301.ECs4778,iEcDH1_1363.EcDH1_4131,iEcHS_1320.EcHS_A4073,iEcolC_1368.EcolC_4160,iG2583_1286.G2583_4648,iJO1366.b3850,iJR904.b3850,iLF82_1304.LF82_0981,iNRG857_1313.NRG857_19220,iSDY_1059.SDY_3895,iUMN146_1321.UM146_19505,iUMNK88_1353.UMNK88_4678,iUTI89_1310.UTI89_C4435,iY75_1357.Y75_RS17835,iZ_1308.Z5372,ic_1306.c4797 Flavodoxin_5 k141_15396_1 270374.MELB17_14301 5.32e-42 152.0 COG0438@1|root,COG0438@2|Bacteria,1NYTU@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k141_3536_1 1255043.TVNIR_3611 9.98e-211 596.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales 135613|Chromatiales C reductase, alpha subunit - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_11231_1 1121918.ARWE01000001_gene2971 2.24e-24 99.8 COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions 1224|Proteobacteria G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 k141_14710_1 870187.Thini_1080 3.85e-45 153.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_14710_2 666685.R2APBS1_3578 3.85e-59 191.0 COG3000@1|root,COG3000@2|Bacteria,1N39U@1224|Proteobacteria,1T0EM@1236|Gammaproteobacteria,1XD0B@135614|Xanthomonadales 135614|Xanthomonadales I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_5643_1 1288826.MSNKSG1_17226 9.06e-22 92.0 COG2207@1|root,COG2207@2|Bacteria,1RH01@1224|Proteobacteria,1S57M@1236|Gammaproteobacteria,46CNC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_5643_2 1288826.MSNKSG1_17231 2.83e-181 520.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,46466@72275|Alteromonadaceae 1236|Gammaproteobacteria H arginine decarboxylase speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Orn_Arg_deC_N k141_4926_1 1415754.JQMK01000012_gene1282 2.99e-43 159.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,464FC@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_45_1 2340.JV46_22530 3.86e-140 409.0 COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,1JBNA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M HlyD family secretion protein - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_3,HlyD_D23,OEP k141_3537_1 95619.PM1_0217265 4.06e-30 121.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_755_2 1288826.MSNKSG1_02008 0.0 1573.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,1RPQ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 - - DUF2156,LPG_synthase_TM k141_755_3 1288826.MSNKSG1_02013 6.4e-34 122.0 COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria 1236|Gammaproteobacteria T membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF347 k141_16790_1 1278309.KB907099_gene2843 0.0 1154.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XHUD@135619|Oceanospirillales 135619|Oceanospirillales L Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_1454_1 1278309.KB907100_gene2022 2.24e-215 602.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1XH88@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family dbpA - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_12621_1 1288826.MSNKSG1_05491 2.72e-128 367.0 COG3031@1|root,COG3031@2|Bacteria,1NHQ4@1224|Proteobacteria,1SHIQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretion system protein C - - - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC k141_12621_2 1288826.MSNKSG1_05496 7.73e-44 154.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,464D8@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_7747_1 1278309.KB907100_gene2351 1.38e-124 361.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,1XIP1@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH k141_11257_2 1469613.JT55_08260 1.8e-80 255.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,3FDSD@34008|Rhodovulum 28211|Alphaproteobacteria EGP Major Facilitator Superfamily MA20_01870 - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr k141_11924_1 1209072.ALBT01000013_gene3615 1.02e-36 138.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1FGE4@10|Cellvibrio 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_20295_1 1353528.DT23_03020 1.28e-16 77.8 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,2XNE6@285107|Thioclava 28211|Alphaproteobacteria U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_20295_2 1123360.thalar_01368 5.42e-57 191.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_13319_2 1469607.KK073768_gene464 2.82e-26 102.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1HM7U@1161|Nostocales 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_14007_1 1328313.DS2_03665 8.94e-57 196.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,465R9@72275|Alteromonadaceae 1236|Gammaproteobacteria T HD domain - - - - - - - - - - - - GAF,GAF_2,HD,HD_5,Lactamase_B_2 k141_1456_1 1121939.L861_11560 1.25e-15 76.6 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XJ73@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_1456_2 1286106.MPL1_03618 7.42e-40 138.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,462YT@72273|Thiotrichales 72273|Thiotrichales Q PFAM Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_16792_1 391615.ABSJ01000045_gene2021 9.48e-20 88.2 COG3017@1|root,COG3017@2|Bacteria 2|Bacteria M protein transport lolB GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - ko:K02494 - - - - ko00000 - - - LolB k141_14716_1 1288826.MSNKSG1_05671 6.03e-289 789.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,467I6@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 2.6.1.1,2.6.1.84 ko:K00812,ko:K12252 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197 RC00006,RC00008 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_14716_2 1288826.MSNKSG1_05666 0.0 966.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase - - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_14716_3 1288826.MSNKSG1_05661 2.63e-85 253.0 COG4446@1|root,COG4446@2|Bacteria 2|Bacteria P Protein conserved in bacteria - - - - - - - - - - - - DUF1499 k141_14716_4 1288826.MSNKSG1_05656 1.04e-228 633.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,4666W@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bkdA1 - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_12622_1 1479237.JMLY01000001_gene2344 3.06e-105 323.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,469FR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_14008_1 1237149.C900_01982 2.2e-42 159.0 COG2911@1|root,COG3210@1|root,COG3637@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety oprH - - ko:K02014,ko:K16087 - - - - ko00000,ko02000 1.B.14,1.B.14.2 - - OMP_b-brl,fn3 k141_4230_2 1123400.KB904751_gene943 9.78e-08 56.2 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA_membrane k141_16089_1 1288826.MSNKSG1_14462 3.89e-203 565.0 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,466NG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Allophanate hydrolase subunit 2 - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - CT_A_B k141_18179_1 1288826.MSNKSG1_02138 7.03e-91 269.0 COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,1S8AC@1236|Gammaproteobacteria,468IJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG k141_18179_2 616991.JPOO01000003_gene784 5.64e-35 133.0 COG1917@1|root,COG1917@2|Bacteria,4NRZM@976|Bacteroidetes,1I5G8@117743|Flavobacteriia 976|Bacteroidetes S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_18179_3 1288826.MSNKSG1_02143 6.17e-150 426.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,466P4@72275|Alteromonadaceae 1236|Gammaproteobacteria C aldo keto reductase yhdN - 1.1.1.65 ko:K05275,ko:K18471 ko00640,ko00750,ko01100,ko01120,map00640,map00750,map01100,map01120 - R01708,R10718 RC00116,RC00739 ko00000,ko00001,ko01000 - - - Aldo_ket_red k141_3544_1 754476.Q7A_994 1.77e-72 233.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,45ZQZ@72273|Thiotrichales 72273|Thiotrichales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - ATPase,ChlI k141_10524_1 697282.Mettu_3861 5.38e-87 270.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1XEMS@135618|Methylococcales 135618|Methylococcales F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_13321_1 399739.Pmen_4142 6.24e-09 59.3 2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1YFVD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - BiPBP_C,DUF4124 k141_12783_3 754476.Q7A_2986 2.25e-62 202.0 COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales 72273|Thiotrichales G PFAM pfkB family carbohydrate kinase - - 2.7.1.3 ko:K00846 ko00051,ko01100,ko01120,map00051,map01100,map01120 - R00866,R03819 RC00002,RC00017,RC00608 ko00000,ko00001,ko01000,ko04147 - - - PfkB,Rieske k141_5074_1 319224.Sputcn32_2165 8.71e-11 75.1 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,2QAGA@267890|Shewanellaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_14160_1 1028801.RG1141_CH24530 1.77e-24 97.1 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,4BF16@82115|Rhizobiaceae 28211|Alphaproteobacteria S Yqey-like protein MA20_04985 - - ko:K09117 - - - - ko00000 - - - YqeY k141_904_1 1046724.KB889897_gene3384 5.56e-82 253.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,465F2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k141_20466_1 517417.Cpar_1982 1.57e-18 82.0 COG3245@1|root,COG3245@2|Bacteria,1FFEJ@1090|Chlorobi 1090|Chlorobi C PFAM cytochrome c, class I - - - - - - - - - - - - Cytochrome_CBB3 k141_20466_2 1232683.ADIMK_3297 3.73e-65 206.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,466NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_1614_1 195250.CM001776_gene1742 2.06e-09 60.1 COG0282@1|root,COG0282@2|Bacteria,1G214@1117|Cyanobacteria,1GZQI@1129|Synechococcus 1117|Cyanobacteria F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_1614_2 1537915.JU57_03365 3.2e-26 107.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,42PG5@68525|delta/epsilon subdivisions 1224|Proteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_3011_1 869213.JCM21142_73011 1.87e-83 268.0 COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia 976|Bacteroidetes C Monomeric isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_12079_1 1294273.roselon_00846 7.53e-39 135.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,2TR97@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain mtrA - - - - - - - - - - - Response_reg,Trans_reg_C k141_12079_2 391626.OAN307_c47430 5.13e-09 57.4 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25,4.1.99.12 ko:K01497,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 k141_15578_1 1318628.MARLIPOL_03080 1.11e-150 437.0 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,46644@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_13464_1 187272.Mlg_2765 1.65e-23 97.4 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1WWT0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k141_3704_1 1122197.ATWI01000011_gene436 4.01e-132 402.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_5075_1 1279017.AQYJ01000020_gene1354 2.83e-14 76.6 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1S61M@1236|Gammaproteobacteria,467SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_20467_1 1163617.SCD_n02361 9.3e-56 192.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3 k141_3012_1 395493.BegalDRAFT_2963 1.59e-31 117.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,463JA@72273|Thiotrichales 72273|Thiotrichales S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K07018 - - - - ko00000 - - - Peptidase_S15 k141_21183_1 396588.Tgr7_1428 1.48e-35 125.0 2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,1SSSK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21183_2 472759.Nhal_1105 5.83e-36 130.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1WY14@135613|Chromatiales 135613|Chromatiales T PFAM Phosphoglycerate mutase - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_905_1 631362.Thi970DRAFT_01926 1.54e-10 58.9 2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,1SBDA@1236|Gammaproteobacteria,1WZ0Q@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_11397_1 1278309.KB907102_gene81 8.25e-93 287.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XHC9@135619|Oceanospirillales 135619|Oceanospirillales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_11397_2 1278309.KB907102_gene80 1.23e-147 425.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XHA2@135619|Oceanospirillales 135619|Oceanospirillales U type II secretion system protein pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_14875_2 82654.Pse7367_0512 3.21e-70 251.0 COG0457@1|root,COG0457@2|Bacteria,1G1UY@1117|Cyanobacteria 1117|Cyanobacteria S Alternative locus ID - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8 k141_12080_1 1049564.TevJSym_ai00150 3.98e-35 126.0 COG2716@1|root,COG2716@2|Bacteria,1RB6J@1224|Proteobacteria,1S2A4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 k141_12080_2 991905.SL003B_3652 3.11e-10 60.8 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,4BQGS@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 - R00653 RC00165,RC00323 ko00000,ko00001,ko01000 - - - Pep_deformylase k141_19071_1 713586.KB900536_gene1925 1.96e-69 231.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales 135613|Chromatiales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_17647_1 713586.KB900536_gene76 2.12e-50 173.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1WWHF@135613|Chromatiales 135613|Chromatiales EGP Major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_14161_1 1123518.ARWI01000001_gene1409 1.48e-91 286.0 COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P k141_1615_1 1163617.SCD_n02852 1.19e-127 386.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria 28216|Betaproteobacteria P von Willebrand factor, type A cbbO2 - - - - - - - - - - - VWA,VWA_2 k141_20468_1 1288826.MSNKSG1_14982 1.02e-37 134.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,465UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iJN746.PP_0110 UbiA k141_20468_2 1288826.MSNKSG1_14987 8.23e-72 220.0 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,46751@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems scoP - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_2274_1 1288826.MSNKSG1_07383 2.91e-98 306.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,464M6@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_2274_2 1288826.MSNKSG1_07388 9.02e-81 239.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,467VM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_2274_3 1288826.MSNKSG1_07393 2.3e-66 201.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,468RS@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspD GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_2274_4 1288826.MSNKSG1_07398 1.99e-143 405.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,466JR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_2274_5 1288826.MSNKSG1_07403 8.2e-105 302.0 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,1S970@1236|Gammaproteobacteria,467X8@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ GO:0003674,GO:0003824,GO:0004787,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0017111 3.6.1.55 ko:K03574,ko:K12152 - - - - ko00000,ko01000,ko03400 - - iSbBS512_1146.SbBS512_E1312 NUDIX k141_2274_6 1288826.MSNKSG1_07408 6.74e-287 783.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,464B7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_2274_7 1288826.MSNKSG1_07413 1.82e-141 400.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,467AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S High frequency lysogenization protein HflD homolog hflD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - ko:K07153 - - - - ko00000 - - - DUF489 k141_2274_8 1288826.MSNKSG1_07418 0.0 893.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_2274_9 1288826.MSNKSG1_07423 1.1e-68 217.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,464Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_15579_1 713586.KB900536_gene134 6.28e-87 274.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales 135613|Chromatiales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k141_3706_1 1530186.JQEY01000005_gene3481 5.2e-64 212.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 k141_4414_1 1278309.KB907100_gene1976 3.65e-87 258.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1XJRB@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase k141_4414_2 1278309.KB907100_gene1977 6.61e-240 662.0 COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XHR9@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_4414_3 1278309.KB907100_gene1978 7.6e-145 410.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XJF1@135619|Oceanospirillales 135619|Oceanospirillales H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_4414_4 1278309.KB907100_gene1979 1.72e-115 341.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1XIAX@135619|Oceanospirillales 135619|Oceanospirillales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_10696_1 216591.BCAM0209 1.72e-59 204.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,1KGRE@119060|Burkholderiaceae 28216|Betaproteobacteria M polysaccharide export epsE - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_10696_2 298386.PBPRA2686 9.06e-71 250.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XTE5@135623|Vibrionales 135623|Vibrionales D protein involved in exopolysaccharide biosynthesis wzc - - ko:K16692 - - - - ko00000,ko01000,ko01001 - - - AAA_31,GNVR,Wzz k141_198_1 998088.B565_0493 2.96e-126 375.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1Y3TY@135624|Aeromonadales 135624|Aeromonadales L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_13466_1 1232683.ADIMK_0630 1.12e-45 167.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ycbB - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_15580_1 1042375.AFPL01000036_gene3017 4.42e-66 212.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria P phosphate transporter pitA GO:0000041,GO:0003674,GO:0005215,GO:0005315,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006817,GO:0006820,GO:0006829,GO:0008150,GO:0008324,GO:0008509,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015654,GO:0015672,GO:0015698,GO:0015710,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1902600 - ko:K03306,ko:K16322 - - - - ko00000,ko02000 2.A.20,2.A.20.1 - iECABU_c1320.ECABU_c33930,iECO111_1330.ECO111_4301,iPC815.YPO3967 PHO4 k141_18344_1 1278307.KB907020_gene896 4.37e-25 100.0 2BN8J@1|root,32GW0@2|Bacteria,1RH74@1224|Proteobacteria,1S7A4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LPP20 lipoprotein - - - - - - - - - - - - LPP20 k141_12785_1 945713.IALB_1951 3.59e-10 65.1 28Q4X@1|root,2ZCN0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_12785_2 1163409.UUA_16638 5.4e-50 172.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1X60V@135614|Xanthomonadales 135614|Xanthomonadales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_17648_1 1395571.TMS3_0114800 9.56e-156 452.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_2275_1 1168067.JAGP01000001_gene678 7.72e-132 378.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4603D@72273|Thiotrichales 72273|Thiotrichales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_14162_1 1278309.KB907101_gene515 4.59e-49 160.0 COG2105@1|root,COG2105@2|Bacteria,1RHE8@1224|Proteobacteria,1S708@1236|Gammaproteobacteria,1XKFK@135619|Oceanospirillales 135619|Oceanospirillales S AIG2-like family - - - - - - - - - - - - AIG2_2 k141_14162_2 207954.MED92_14668 2.92e-36 124.0 COG5460@1|root,COG5460@2|Bacteria,1N7MS@1224|Proteobacteria,1SCTR@1236|Gammaproteobacteria,1XM7X@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized conserved protein (DUF2164) - - - - - - - - - - - - DUF2164 k141_8584_1 675812.VHA_001339 5.81e-42 155.0 COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XSDG@135623|Vibrionales 135623|Vibrionales Q MlaD protein pqiB - - ko:K06192 - - - - ko00000 - - - MlaD k141_3014_1 1288826.MSNKSG1_06273 4.37e-71 215.0 COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria,467ZA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_3014_2 1288826.MSNKSG1_06268 8.33e-77 231.0 COG3937@1|root,COG3937@2|Bacteria,1N7X8@1224|Proteobacteria,1T08C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Polyhydroxyalkanoate granule-associated protein - - - - - - - - - - - - Phasin k141_3014_3 1288826.MSNKSG1_06263 6e-54 173.0 COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,1S6PU@1236|Gammaproteobacteria,46DGN@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR,TetR_N k141_5078_3 243233.MCA2730 1.22e-30 112.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XF23@135618|Methylococcales 135618|Methylococcales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_4415_1 870187.Thini_4244 2.06e-13 69.3 COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RMCU@1236|Gammaproteobacteria,461XW@72273|Thiotrichales 72273|Thiotrichales H Cobyrinic acid A,C-diamide - - 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 - - - CbiA,GATase_3 k141_4415_2 1163617.SCD_n02705 2.1e-32 117.0 COG0316@1|root,COG0316@2|Bacteria,1N8ZN@1224|Proteobacteria,2W5FR@28216|Betaproteobacteria 28216|Betaproteobacteria S Iron-sulphur cluster biosynthesis - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_20470_1 446470.Snas_5093 7.99e-11 65.1 COG1309@1|root,COG1309@2|Bacteria,2H47F@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N k141_1617_1 697282.Mettu_0508 4.21e-06 48.5 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1XF2P@135618|Methylococcales 135618|Methylococcales K response regulator - - - - - - - - - - - - GerE,Response_reg k141_18345_1 196164.23494573 1.23e-23 96.3 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,22NT6@1653|Corynebacteriaceae 201174|Actinobacteria K Cold shock proteins cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_6466_1 207954.MED92_13568 2.55e-64 201.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XIW0@135619|Oceanospirillales 135619|Oceanospirillales H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_1636_2 1238190.AMQY01000003_gene1659 1.51e-28 112.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XHQ9@135619|Oceanospirillales 135619|Oceanospirillales M heptosyltransferase waaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_3035_1 1121035.AUCH01000001_gene1821 3.86e-84 271.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,2KUS5@206389|Rhodocyclales 206389|Rhodocyclales C nitrite reductase NAD(P)H nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_13484_1 266779.Meso_2283 1.21e-114 345.0 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,43II5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M RND family efflux transporter, MFP subunit - - - ko:K02005 - - - - ko00000 - - - HlyD_3 k141_13484_2 1082933.MEA186_07849 6.1e-160 478.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,43JFR@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_3733_1 1288826.MSNKSG1_17995 2.2e-133 424.0 COG3210@1|root,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,46D54@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S8 family mshQ - - ko:K12287 - - - - ko00000,ko02044 - - - Bactofilin,Laminin_G_3,PA14 k141_3733_2 1288826.MSNKSG1_18000 0.0 935.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,463YY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_3733_3 1288826.MSNKSG1_18005 1.78e-164 466.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,46416@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase, nitrogen specific glnL GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_21851_2 998674.ATTE01000001_gene4298 1.87e-27 103.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,460ID@72273|Thiotrichales 72273|Thiotrichales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_17668_1 1449351.RISW2_05190 1.2e-06 52.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,4KKHW@93682|Roseivivax 28211|Alphaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_362_1 1278309.KB907100_gene2176 7.88e-05 43.1 COG1522@1|root,COG1522@2|Bacteria,1R7SW@1224|Proteobacteria,1S4QN@1236|Gammaproteobacteria,1XJSC@135619|Oceanospirillales 135619|Oceanospirillales K COG1522 Transcriptional regulators - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_362_2 717774.Marme_0485 1.57e-122 362.0 COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,1XPQY@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_362_3 400668.Mmwyl1_4063 5.29e-130 379.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1S2UC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_362_4 1278309.KB907100_gene2175 4.05e-137 399.0 COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,1S2NP@1236|Gammaproteobacteria,1XJSG@135619|Oceanospirillales 135619|Oceanospirillales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_17791_1 1278309.KB907102_gene75 2.21e-42 149.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1XHHB@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_17791_2 1278309.KB907102_gene76 9.8e-64 203.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1XJAD@135619|Oceanospirillales 135619|Oceanospirillales HL COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,NUDIX_4,TMP-TENI k141_11514_1 575788.VS_2142 7.97e-42 159.0 29W90@1|root,30HUD@2|Bacteria,1R92S@1224|Proteobacteria,1S1CJ@1236|Gammaproteobacteria,1XYU1@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_10079_1 1288826.MSNKSG1_18450 0.0 1745.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,46514@72275|Alteromonadaceae 1236|Gammaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_10079_2 1288826.MSNKSG1_18455 4.7e-123 350.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,467DX@72275|Alteromonadaceae 1236|Gammaproteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_10079_3 1288826.MSNKSG1_18460 1.86e-106 306.0 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,467DE@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 fkpB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_10079_4 1288826.MSNKSG1_18465 3e-222 613.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,465MC@72275|Alteromonadaceae 1236|Gammaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 LYTB k141_10079_5 1288826.MSNKSG1_18470 6.19e-134 380.0 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,468XR@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4970 Tfp pilus assembly protein FimT fimT - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_10079_6 1288826.MSNKSG1_18475 3.33e-114 329.0 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,46937@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4967 Tfp pilus assembly protein PilV pilV - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_6576_1 1123228.AUIH01000031_gene1705 2.23e-13 73.2 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1S1G2@1236|Gammaproteobacteria,1XN8X@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_6576_2 1509405.GV67_11220 3.04e-231 653.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,4B825@82115|Rhizobiaceae 28211|Alphaproteobacteria P Sulfatase pehA - - - - - - - - - - - DUF4976,Sulfatase k141_21298_1 857087.Metme_0196 2.75e-96 287.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1XDNB@135618|Methylococcales 135618|Methylococcales H Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth k141_12912_1 1163408.UU9_11155 1.18e-122 375.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_13582_1 396588.Tgr7_0626 1.26e-64 218.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWQV@135613|Chromatiales 135613|Chromatiales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_12220_1 870187.Thini_1173 5.95e-70 219.0 COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T3U6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family - - 2.1.1.156 ko:K18896 ko00260,map00260 - R10060 RC00003,RC03038 ko00000,ko00001,ko01000 - - - Methyltransf_25 k141_15693_1 1122201.AUAZ01000023_gene2997 8.59e-123 360.0 COG3626@1|root,COG3626@2|Bacteria,1MUBA@1224|Proteobacteria,1RRT5@1236|Gammaproteobacteria,469G0@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bacterial phosphonate metabolism protein (PhnI) phnI GO:0003674,GO:0003824,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061693,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1904176,GO:1990234 2.7.8.37 ko:K06164 ko00440,map00440 - R10185 RC00005,RC00063 ko00000,ko00001,ko01000 - - - PhnI k141_15693_2 1122201.AUAZ01000023_gene2996 2.27e-67 212.0 COG3625@1|root,COG3625@2|Bacteria,1RHXN@1224|Proteobacteria,1RZR8@1236|Gammaproteobacteria,46BBW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bacterial phosphonate metabolism protein (PhnH) phnH GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0042802,GO:0044237,GO:0046434,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1904176,GO:1990234 2.7.8.37 ko:K06165 ko00440,map00440 - R10185 RC00005,RC00063 ko00000,ko00001,ko01000 - - - PhnH k141_19844_1 1267005.KB911255_gene3070 1.74e-12 70.9 COG5338@1|root,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria,2U090@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Protein conserved in bacteria - - - - - - - - - - - - BBP2_2 k141_19844_2 1121035.AUCH01000016_gene2212 4.02e-14 73.6 COG1538@1|root,COG4319@1|root,COG1538@2|Bacteria,COG4319@2|Bacteria,1MYX2@1224|Proteobacteria,2VKDN@28216|Betaproteobacteria,2KUPB@206389|Rhodocyclales 206389|Rhodocyclales MU COG1538 Outer membrane protein - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - DUF4440,OEP k141_363_1 396588.Tgr7_1678 2.06e-05 47.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WXQZ@135613|Chromatiales 135613|Chromatiales L Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_4555_1 472759.Nhal_2480 3.46e-124 367.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1WXJN@135613|Chromatiales 135613|Chromatiales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_4555_2 631454.N177_2798 2.49e-22 97.8 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,1JQ04@119043|Rhodobiaceae 28211|Alphaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MA20_44845 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_8086_1 1288826.MSNKSG1_06403 0.0 951.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_8086_2 1288826.MSNKSG1_06398 9.14e-197 545.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,466DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_6577_1 4155.Migut.F01470.1.p 9.68e-142 404.0 COG1007@1|root,KOG4668@2759|Eukaryota,37KVW@33090|Viridiplantae,3GH1R@35493|Streptophyta,44UT6@71274|asterids 35493|Streptophyta C Proton-conducting membrane transporter - - 1.6.5.3 ko:K05573 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M k141_19214_1 1123393.KB891329_gene1015 1.58e-62 196.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,1KRJ7@119069|Hydrogenophilales 119069|Hydrogenophilales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_1061_2 1298593.TOL_0771 1.77e-13 69.7 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XIHM@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_13600_2 998088.B565_0962 2.07e-14 71.2 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1Y3DQ@135624|Aeromonadales 135624|Aeromonadales K hydrogen peroxide-inducible genes - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_16354_1 1396858.Q666_13915 3.62e-74 256.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases bprV - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - PKD,PPC,Peptidase_S8 k141_16354_2 1288826.MSNKSG1_09423 4.16e-56 191.0 COG1593@1|root,COG1593@2|Bacteria,1PJM6@1224|Proteobacteria,1RPHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_7332_1 1215092.PA6_008_01330 4.19e-29 116.0 COG0840@1|root,COG0840@2|Bacteria,1NYH1@1224|Proteobacteria,1SR36@1236|Gammaproteobacteria,1YJS9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_7332_2 1452718.JBOY01000073_gene3042 1.76e-29 116.0 COG0526@1|root,COG0526@2|Bacteria,1NKKH@1224|Proteobacteria,1SHZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Thiol-disulfide isomerase - - - - - - - - - - - - - k141_12932_1 1283300.ATXB01000001_gene1089 9.98e-77 244.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales 135618|Methylococcales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_1779_1 1288826.MSNKSG1_13752 8.92e-47 161.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,46495@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump VVA1228 - - - - - - - - - - - MatE k141_1779_2 1288826.MSNKSG1_13757 1.06e-94 276.0 COG0824@1|root,COG0824@2|Bacteria,1RF7Q@1224|Proteobacteria,1S7PD@1236|Gammaproteobacteria,468NH@72275|Alteromonadaceae 1236|Gammaproteobacteria S thioesterase - - - - - - - - - - - - 4HBT_2 k141_15720_1 1122603.ATVI01000007_gene1691 8.65e-96 288.0 COG2813@1|root,COG2813@2|Bacteria,1QWWU@1224|Proteobacteria,1T5SK@1236|Gammaproteobacteria,1XARZ@135614|Xanthomonadales 1224|Proteobacteria J Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_15720_3 1117379.BABA_11811 1.72e-48 166.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_12240_1 1288826.MSNKSG1_00231 7.97e-35 125.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,4677I@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_12240_2 1288826.MSNKSG1_00236 1.31e-202 559.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_12240_3 1288826.MSNKSG1_00241 7.65e-181 503.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,464KC@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422 Thymidylat_synt k141_13601_2 690597.JH730973_gene2643 2.12e-24 104.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1YMN0@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_19861_1 225937.HP15_2149 6.56e-46 158.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19861_2 1117319.PSPO_00842 5.52e-137 420.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_1062_1 225937.HP15_1911 4.36e-81 264.0 COG2755@1|root,COG3299@1|root,COG4932@1|root,COG2755@2|Bacteria,COG3299@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 3.1.1.5,3.2.1.78 ko:K01218,ko:K10804,ko:K20276 ko00051,ko01040,ko02024,map00051,map01040,map02024 - R01332 RC00467 ko00000,ko00001,ko01000,ko01004 - GH26 - Baseplate_J,GGACT,Laminin_G_3,Lipase_GDSL_2,PA14 k141_14983_1 1247024.JRLH01000002_gene155 8.3e-19 84.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Colicin v production cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V k141_14983_2 631362.Thi970DRAFT_04963 3.17e-133 393.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1WWAI@135613|Chromatiales 135613|Chromatiales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_7333_1 396588.Tgr7_3255 1.38e-77 252.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales 135613|Chromatiales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_19233_1 399795.CtesDRAFT_PD1148 4.02e-08 55.5 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2VMYY@28216|Betaproteobacteria,4ADCN@80864|Comamonadaceae 28216|Betaproteobacteria C nitroreductase - - - - - - - - - - - - Nitroreductase k141_19233_2 265072.Mfla_2286 6.95e-16 73.2 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VW2N@28216|Betaproteobacteria,2KMZD@206350|Nitrosomonadales 206350|Nitrosomonadales K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_21316_1 999611.KI421504_gene3152 9.79e-131 379.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2TSIQ@28211|Alphaproteobacteria,27ZZ5@191028|Leisingera 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13602_1 1002340.AFCF01000065_gene24 7.48e-10 55.1 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2U95S@28211|Alphaproteobacteria,34FP8@302485|Phaeobacter 28211|Alphaproteobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 k141_13602_2 367336.OM2255_07905 3.76e-68 208.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2U96X@28211|Alphaproteobacteria 28211|Alphaproteobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_13602_3 1417296.U879_04550 8.52e-16 73.9 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_20617_1 396588.Tgr7_2184 7.94e-87 265.0 COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales 135613|Chromatiales Q Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD k141_20617_2 396588.Tgr7_2183 9.6e-22 85.9 2E3CD@1|root,32YBP@2|Bacteria,1N8PD@1224|Proteobacteria,1SCSK@1236|Gammaproteobacteria,1WZ7C@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_1063_1 279238.Saro_2813 1.08e-32 116.0 COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,2U89S@28211|Alphaproteobacteria,2KDD2@204457|Sphingomonadales 204457|Sphingomonadales S Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA k141_16355_1 52598.EE36_05928 2.05e-128 392.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria,3ZWCP@60136|Sulfitobacter 28211|Alphaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain fdhF - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_18464_1 1278309.KB907101_gene744 3.19e-263 739.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1XI15@135619|Oceanospirillales 135619|Oceanospirillales S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_18464_2 1278309.KB907101_gene743 3.41e-42 145.0 COG0705@1|root,COG0705@2|Bacteria,1NG54@1224|Proteobacteria,1SF6D@1236|Gammaproteobacteria,1XMEP@135619|Oceanospirillales 135619|Oceanospirillales S Rhomboid family - - - - - - - - - - - - Rhomboid k141_7334_1 314270.RB2083_1782 1.65e-70 232.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,3ZGRW@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C NADH flavin fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_12241_1 1288826.MSNKSG1_06228 1.42e-91 273.0 COG0300@1|root,COG0300@2|Bacteria,1RFF2@1224|Proteobacteria,1S4ME@1236|Gammaproteobacteria,46CWM@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_12241_2 1288826.MSNKSG1_06233 3.07e-102 306.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,464DX@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_15721_2 713586.KB900536_gene2157 7.85e-48 158.0 COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1SCPK@1236|Gammaproteobacteria,1X264@135613|Chromatiales 135613|Chromatiales S Membrane - - - - - - - - - - - - - k141_13603_1 2340.JV46_13870 1.98e-47 157.0 2DZRC@1|root,32VGV@2|Bacteria,1N2PT@1224|Proteobacteria,1SQQ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Cytochrom_C_2 k141_3195_1 1278309.KB907109_gene3290 2.91e-199 564.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XHV2@135619|Oceanospirillales 135619|Oceanospirillales E acetolactate synthase ilvB-1 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_3195_2 1278309.KB907109_gene3289 1.45e-40 135.0 2E2KE@1|root,32XPQ@2|Bacteria,1N3CH@1224|Proteobacteria,1S951@1236|Gammaproteobacteria,1XKS5@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14984_1 1121013.P873_11430 1.04e-22 102.0 COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_1064_1 391595.RLO149_c015670 6.32e-67 217.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2TT73@28211|Alphaproteobacteria,2P2GI@2433|Roseobacter 28211|Alphaproteobacteria F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_1064_2 998674.ATTE01000001_gene1584 4.92e-25 103.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,462HR@72273|Thiotrichales 72273|Thiotrichales G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 k141_7335_1 1121918.ARWE01000001_gene2703 4.03e-59 191.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH k141_6592_1 1288826.MSNKSG1_16146 7.19e-72 223.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,466A4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015889,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0031419,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - ko:K02016,ko:K06858 ko02010,map02010 M00240,M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13,3.A.1.14 - iECH74115_1262.ECH74115_0168,iECSP_1301.ECSP_0159,iECs_1301.ECs0162,iZ_1308.Z0169 Peripla_BP_2 k141_6592_2 1288826.MSNKSG1_16141 0.0 1162.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,466DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG4206 Outer membrane cobalamin receptor protein btuB GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - iECB_1328.ECB_03851,iECP_1309.ECP_4183,iSF_1195.SF4048,iS_1188.S3696 Plug,TonB_dep_Rec k141_6592_3 1288826.MSNKSG1_16136 0.0 901.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,46521@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains VP1725 - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_18465_1 1353537.TP2_09040 1.44e-110 330.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2XMQD@285107|Thioclava 28211|Alphaproteobacteria C catalyzes the oxidation of dihydrolipoamide to lipoamide lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_15722_1 1000565.METUNv1_00181 9.84e-31 113.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2VT6I@28216|Betaproteobacteria,2KZAQ@206389|Rhodocyclales 206389|Rhodocyclales K Belongs to the Fur family - - - ko:K09826 - - - - ko00000,ko03000 - - - FUR k141_15722_2 1049564.TevJSym_am00320 1.36e-05 46.6 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1J9H8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E FAD dependent oxidoreductase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_5230_1 1255043.TVNIR_2520 3e-08 55.8 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales 135613|Chromatiales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_5230_2 1439940.BAY1663_04671 5.94e-37 128.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_5230_3 90814.KL370891_gene1698 9.15e-64 199.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,460QK@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_5230_4 765913.ThidrDRAFT_2324 9.07e-70 218.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales 135613|Chromatiales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k141_5230_5 396588.Tgr7_2271 2.18e-84 266.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales 135613|Chromatiales J TIGRFAM ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_8105_1 1238190.AMQY01000018_gene1260 5.38e-28 109.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales 135619|Oceanospirillales L TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_8105_2 713586.KB900536_gene1933 6.31e-39 150.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X2AG@135613|Chromatiales 135613|Chromatiales T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc,PilZ k141_18592_2 1461693.ATO10_02690 1.19e-68 215.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_498_1 580332.Slit_0396 6.74e-165 488.0 COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,2VIRI@28216|Betaproteobacteria 28216|Betaproteobacteria G Glucodextranase, domain N - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - CBM_20,Glucodextran_N,Glyco_hydro_15 k141_2554_1 396588.Tgr7_1545 1.53e-08 53.5 COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Lipopolysaccharide assembly protein A domain - - - ko:K08992 - - - - ko00000 - - - LapA_dom k141_2554_2 396588.Tgr7_1544 3.69e-48 155.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales 135613|Chromatiales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_2554_3 870187.Thini_0284 1.04e-14 74.3 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales 72273|Thiotrichales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_10958_1 1278309.KB907105_gene1531 1.12e-125 361.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1XH58@135619|Oceanospirillales 135619|Oceanospirillales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_11634_1 555778.Hneap_0272 3.26e-63 216.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1X0DW@135613|Chromatiales 135613|Chromatiales Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_3931_1 398580.Dshi_2132 1.93e-244 680.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran k141_4697_1 105559.Nwat_2339 9.31e-91 291.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales 135613|Chromatiales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_10232_1 1401067.HMPREF0872_01630 0.000269 44.3 COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,4H25K@909932|Negativicutes 909932|Negativicutes M lipopolysaccharide heptosyltransferase rfaF - - ko:K02841,ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_16498_1 1000565.METUNv1_02454 4.3e-115 359.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales 206389|Rhodocyclales T CHASE2 - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_16498_2 1123401.JHYQ01000014_gene822 2.12e-112 332.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,461ME@72273|Thiotrichales 72273|Thiotrichales V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran k141_8203_1 1278309.KB907106_gene1298 4.02e-73 221.0 COG0517@1|root,COG0517@2|Bacteria,1N2TU@1224|Proteobacteria,1S9T1@1236|Gammaproteobacteria,1XRFP@135619|Oceanospirillales 135619|Oceanospirillales S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_8203_2 1278309.KB907106_gene1297 1.18e-64 206.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XIVQ@135619|Oceanospirillales 135619|Oceanospirillales C Aldo keto reductase tas - - - - - - - - - - - Aldo_ket_red k141_13068_1 1131553.JIBI01000010_gene1373 1.28e-05 46.6 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales 28216|Betaproteobacteria H Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_13068_2 1123517.JOMR01000001_gene1614 2.04e-16 79.7 COG2199@1|root,COG2199@2|Bacteria,1NYG9@1224|Proteobacteria,1RV5M@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,Protoglobin k141_13750_2 1232683.ADIMK_2197 1.27e-143 410.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,464WQ@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0412 Dienelactone hydrolase and related enzymes yghX - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_6014_1 1278309.KB907100_gene2221 2.91e-182 511.0 COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,1RYUD@1236|Gammaproteobacteria,1XJ4Q@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase FAD-binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1 k141_6014_2 1232683.ADIMK_2195 6.18e-80 245.0 COG0208@1|root,COG0208@2|Bacteria,1QXP8@1224|Proteobacteria,1S1U9@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k141_5389_1 391613.RTM1035_16647 1.12e-121 361.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,46QHR@74030|Roseovarius 28211|Alphaproteobacteria H COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II MA20_29420 - 6.2.1.48 ko:K00666,ko:K02182 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_1210_1 1288826.MSNKSG1_01593 4.72e-90 266.0 COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,1S2UP@1236|Gammaproteobacteria,467I3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k141_1210_2 1288826.MSNKSG1_01588 3.12e-71 214.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,467AU@72275|Alteromonadaceae 1236|Gammaproteobacteria P Zn-ribbon-containing protein involved in phosphonate metabolism phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_1210_3 1288826.MSNKSG1_01583 9.67e-112 323.0 COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,1S9AU@1236|Gammaproteobacteria,467UN@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine phosphatase superfamily (branch 1) - - - - - - - - - - - - His_Phos_1 k141_1210_4 1288826.MSNKSG1_01578 9.53e-110 315.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,467BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 k141_1210_5 1288826.MSNKSG1_01573 1.68e-264 725.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH k141_1210_6 1288826.MSNKSG1_01568 2e-97 283.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S990@1236|Gammaproteobacteria,467D2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_1210_7 1288826.MSNKSG1_01563 1.51e-191 531.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,465MT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0656 Aldo keto reductases, related to diketogulonate reductase dkgB GO:0003674,GO:0003824,GO:0004033,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0047681,GO:0051596,GO:0055114,GO:0071704,GO:1901575,GO:1990002 1.1.1.346 ko:K06222 - - - - ko00000,ko01000 - - iEcolC_1368.EcolC_3458 Aldo_ket_red k141_1210_8 1288826.MSNKSG1_01558 4.2e-120 345.0 2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,1SDJA@1236|Gammaproteobacteria,46C32@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_499_1 744979.R2A130_3353 3.4e-17 80.9 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome c oxidase accessory protein ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_499_2 1342299.Z947_2228 6.62e-73 227.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,3ZWWV@60136|Sulfitobacter 28211|Alphaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_1886_1 1278309.KB907099_gene2855 2.74e-65 207.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1XI7Y@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type nitrate sulfonate bicarbonate transport system, ATPase component nasD - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_10960_1 272943.RSP_0385 1.17e-103 318.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,1FB5V@1060|Rhodobacter 28211|Alphaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_17938_1 1288826.MSNKSG1_08298 4.53e-71 220.0 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,4640R@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the ParA family fleN - - ko:K04562 - - - - ko00000,ko02035 - - - ParA k141_17938_2 1288826.MSNKSG1_08303 4.28e-292 799.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,464E3@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1419 Flagellar GTP-binding protein flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_17938_3 1288826.MSNKSG1_08308 0.0 1246.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,465FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_12376_1 349521.HCH_01134 3.64e-49 178.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQAF@1236|Gammaproteobacteria,1XI9H@135619|Oceanospirillales 135619|Oceanospirillales NT Nitrate and nitrite sensing - - - - - - - - - - - - MCPsignal,NIT k141_8205_1 1380380.JIAX01000009_gene1735 7.16e-92 284.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type dipeptide transport system periplasmic component dppA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - ko:K12368 ko02010,ko02030,map02010,map02030 M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_1211_1 674977.VMC_39840 2.94e-66 226.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_3932_1 754477.Q7C_417 4.85e-79 245.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,45ZSI@72273|Thiotrichales 72273|Thiotrichales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_3932_2 1120953.AUBH01000012_gene392 3.17e-15 73.9 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,466PY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_17197_1 699248.SRA_07166 1.45e-60 200.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 k141_17197_2 1042375.AFPL01000013_gene2462 1.44e-125 364.0 COG2141@1|root,COG2141@2|Bacteria,1MWI8@1224|Proteobacteria,1S10Y@1236|Gammaproteobacteria,468VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase k141_15854_1 1328313.DS2_19076 1.71e-174 501.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,466QE@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3344 Retron-type reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k141_8792_2 391615.ABSJ01000033_gene693 3.78e-22 93.2 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,1J75P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4 k141_10233_1 566466.NOR53_3392 3e-12 68.6 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1J5QJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_10233_2 717231.Flexsi_0321 1.11e-43 147.0 COG2905@1|root,COG2905@2|Bacteria,2GGGX@200930|Deferribacteres 200930|Deferribacteres T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_18594_1 768671.ThimaDRAFT_2997 8.49e-26 107.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WXV4@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_13752_1 1234364.AMSF01000025_gene3604 1.24e-25 103.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1X3GG@135614|Xanthomonadales 135614|Xanthomonadales S hydrolase of the alpha beta-hydrolase fold - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_13752_2 1442599.JAAN01000045_gene2789 8.48e-61 202.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1X3NQ@135614|Xanthomonadales 135614|Xanthomonadales O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_11636_1 349521.HCH_01557 7.23e-60 211.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XI1I@135619|Oceanospirillales 135619|Oceanospirillales L Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C - - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_4698_1 1215092.PA6_021_01010 1.86e-11 63.5 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1YCSC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Mycolic acid cyclopropane synthetase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - iJN746.PP_2734 CMAS k141_4698_3 118173.KB235914_gene784 7.5e-23 89.7 2E3CN@1|root,32YBX@2|Bacteria,1G8Z2@1117|Cyanobacteria,1HCY7@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_4698_4 1049564.TevJSym_ax00140 3.08e-15 72.0 COG3193@1|root,COG3193@2|Bacteria,1REZG@1224|Proteobacteria,1S5K5@1236|Gammaproteobacteria,1JB26@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_13069_1 225937.HP15_1594 5.42e-211 601.0 2C1AX@1|root,33GUX@2|Bacteria,1MZSH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_15094_1 1288826.MSNKSG1_08518 2.87e-94 286.0 COG4223@1|root,COG4223@2|Bacteria,1NQ3D@1224|Proteobacteria,1T350@1236|Gammaproteobacteria 1236|Gammaproteobacteria DZ transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - - k141_15094_2 1288826.MSNKSG1_08513 7.01e-100 295.0 2E4B7@1|root,32Z6X@2|Bacteria,1N8XS@1224|Proteobacteria,1SENM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2846) - - - - - - - - - - - - DUF2846 k141_19966_1 1278309.KB907107_gene1658 8.14e-48 159.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1XJB3@135619|Oceanospirillales 135619|Oceanospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_19966_2 1278309.KB907107_gene1659 9.85e-257 721.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1XHE3@135619|Oceanospirillales 135619|Oceanospirillales O COG0501 Zn-dependent protease with chaperone function - - - - - - - - - - - - Peptidase_M48 k141_17198_2 266264.Rmet_0429 4.69e-33 124.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,1K3AU@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_8206_2 1288826.MSNKSG1_06253 3.14e-133 381.0 2E5SG@1|root,330GY@2|Bacteria,1NB2M@1224|Proteobacteria,1SCUK@1236|Gammaproteobacteria,468X9@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10962_1 1026882.MAMP_00347 2.36e-94 291.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,46009@72273|Thiotrichales 72273|Thiotrichales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_3933_1 1366046.HIMB11_01181 1.78e-84 258.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2V9BQ@28211|Alphaproteobacteria,3ZIEB@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria M NeuB family - - - - - - - - - - - - NeuB,SAF k141_22080_1 1278309.KB907100_gene2296 4.4e-213 603.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XHGY@135619|Oceanospirillales 135619|Oceanospirillales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_22080_2 1278309.KB907100_gene2295 2.75e-66 203.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XKHZ@135619|Oceanospirillales 135619|Oceanospirillales J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_22080_4 1278309.KB907100_gene2293 0.0 878.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1XHHN@135619|Oceanospirillales 135619|Oceanospirillales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_22080_5 1278309.KB907100_gene2292 2.65e-248 683.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales 135619|Oceanospirillales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_22080_6 1278309.KB907100_gene2291 2.99e-36 131.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XHRC@135619|Oceanospirillales 135619|Oceanospirillales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_17940_1 1380358.JADJ01000011_gene204 6.28e-98 288.0 COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_17940_2 1532558.JL39_14340 9.18e-35 121.0 COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria,4BN16@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - YCII k141_16499_3 187272.Mlg_0457 2.92e-59 184.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1WYRW@135613|Chromatiales 135613|Chromatiales J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k141_1213_1 556268.OFAG_00661 1.08e-55 198.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472C3@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9 k141_13753_1 266809.PM03_00480 1.19e-26 100.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_13753_2 367336.OM2255_08145 1.83e-43 141.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria 28211|Alphaproteobacteria J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_15095_1 1123368.AUIS01000019_gene1218 1.03e-18 82.4 COG1416@1|root,COG1416@2|Bacteria,1N5DH@1224|Proteobacteria,1SF5J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_12399_2 525897.Dbac_0565 6.46e-19 89.0 COG2181@1|root,COG2181@2|Bacteria,1RERF@1224|Proteobacteria,42RXQ@68525|delta/epsilon subdivisions,2WN8Q@28221|Deltaproteobacteria,2MACS@213115|Desulfovibrionales 28221|Deltaproteobacteria C nitrate reductase activity - - - - - - - - - - - - Nitrate_red_gam k141_12399_3 870187.Thini_0278 8.42e-200 567.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,4637B@72273|Thiotrichales 72273|Thiotrichales C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_8 k141_15111_1 765911.Thivi_1064 1.4e-79 265.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k141_1232_1 292415.Tbd_1939 1.24e-15 73.6 2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria,2W3YC@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 k141_3315_1 1042377.AFPJ01000009_gene256 1.33e-90 276.0 COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,46DC2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_8223_1 1123368.AUIS01000005_gene331 2.28e-09 59.3 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,2NCGD@225057|Acidithiobacillales 225057|Acidithiobacillales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N k141_8223_2 1249627.D779_2787 1.47e-27 109.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1WWTH@135613|Chromatiales 135613|Chromatiales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_14373_1 1288826.MSNKSG1_00401 1.03e-32 122.0 COG0664@1|root,COG1639@1|root,COG0664@2|Bacteria,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,466AI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_7488_1 1123392.AQWL01000002_gene1974 1.59e-86 266.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_1994_5 1122201.AUAZ01000001_gene2335 8.07e-21 91.7 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1S9Y1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_7579_1 187272.Mlg_2287 1.38e-238 662.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1WX82@135613|Chromatiales 135613|Chromatiales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_22234_1 63737.Npun_R3608 9.21e-98 296.0 COG3001@1|root,COG3001@2|Bacteria,1G040@1117|Cyanobacteria,1HIFG@1161|Nostocales 1117|Cyanobacteria G PFAM Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - - - - - - - - - - Fructosamin_kin k141_22234_2 1328313.DS2_00370 9.2e-20 92.4 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,4653E@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_5519_1 1298593.TOL_1925 6.19e-35 125.0 2BV15@1|root,32QDR@2|Bacteria,1RJ98@1224|Proteobacteria,1RYP4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_17330_1 1121920.AUAU01000012_gene2678 1.14e-06 57.0 COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria 57723|Acidobacteria O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH k141_17330_2 870187.Thini_2789 7.79e-24 99.4 COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales 72273|Thiotrichales S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_9623_1 1392838.AWNM01000037_gene1038 4.42e-76 240.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VMHS@28216|Betaproteobacteria,3T1R2@506|Alcaligenaceae 28216|Betaproteobacteria I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation fadA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_1365_1 1288826.MSNKSG1_01018 3.03e-131 374.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,464P9@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ompR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_1365_2 1288826.MSNKSG1_01023 1.33e-73 234.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,4640Q@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_623_1 391038.Bphy_4529 3.8e-39 152.0 COG3707@1|root,COG5002@1|root,COG3707@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_8934_1 666509.RCA23_c26410 1.75e-68 219.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2U2F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, periplasmic component - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_1,SBP_bac_11,SBP_bac_6 k141_18759_1 1168067.JAGP01000001_gene1596 1.31e-67 209.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,4634U@72273|Thiotrichales 72273|Thiotrichales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_640_2 870187.Thini_1454 7.85e-61 196.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,46031@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_10422_1 765911.Thivi_2092 1.86e-104 315.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1WVWJ@135613|Chromatiales 135613|Chromatiales E ABC transporter, urea - - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 k141_11740_1 314278.NB231_11309 1.66e-19 93.2 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales 135613|Chromatiales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_20031_1 56780.SYN_01041 8.79e-59 197.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MQWN@213462|Syntrophobacterales 28221|Deltaproteobacteria F Biotin carboxylase C-terminal domain accC - 6.3.4.14,6.4.1.1,6.4.1.2 ko:K01959,ko:K01961 ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376,M00620 R00344,R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_14516_1 365044.Pnap_3921 3.86e-27 111.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,4ADNW@80864|Comamonadaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_8955_1 290397.Adeh_1762 3.72e-19 84.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg k141_8955_2 1114970.PSF113_2292 5.75e-29 119.0 COG0840@1|root,COG0840@2|Bacteria,1NCMF@1224|Proteobacteria,1RRP8@1236|Gammaproteobacteria,1YSI1@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_1378_1 1116472.MGMO_77c00230 8.85e-43 155.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XE5G@135618|Methylococcales 135618|Methylococcales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_3461_1 1278309.KB907099_gene2897 1.34e-28 106.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440,SnoaL_2 k141_3461_2 1286631.X805_22390 7.21e-20 83.6 COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2VVPU@28216|Betaproteobacteria,1KMHU@119065|unclassified Burkholderiales 28216|Betaproteobacteria S PQ loop repeat - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - PQ-loop k141_19460_1 2340.JV46_18900 1.33e-40 138.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Pfam Rhodanese-like - - - - - - - - - - - - Rhodanese k141_19460_2 257313.BP1565 7.33e-28 102.0 COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria,3T4RR@506|Alcaligenaceae 28216|Betaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin k141_19460_4 1122604.JONR01000034_gene431 3.03e-27 102.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif - - - - - - - - - - - - RRM_1 k141_19460_5 1255043.TVNIR_1527 1.61e-30 108.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales 135613|Chromatiales K PFAM Cold-shock protein, DNA-binding - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_13239_1 1463856.JOHY01000015_gene6841 5.35e-43 163.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria 201174|Actinobacteria M TIGRFAM YD repeat protein - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_5537_1 930166.CD58_17350 1.53e-75 240.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,1RRA5@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N k141_5537_2 1122599.AUGR01000014_gene574 1.14e-32 126.0 COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,1RXX8@1236|Gammaproteobacteria,1XI1J@135619|Oceanospirillales 135619|Oceanospirillales M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Alginate_exp k141_16008_1 1163617.SCD_n00836 1.78e-86 271.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria 28216|Betaproteobacteria S peptidase U62, modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_6801_2 768671.ThimaDRAFT_1768 3.26e-15 74.3 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1WYJU@135613|Chromatiales 135613|Chromatiales S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_6187_1 1278309.KB907106_gene1242 1.07e-140 419.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHAU@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9,dCache_1 k141_6187_2 1278309.KB907106_gene1243 1.87e-259 717.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XH6F@135619|Oceanospirillales 135619|Oceanospirillales T Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_18772_1 443144.GM21_0435 1.04e-81 278.0 COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM conserved repeat domain protein - - - - - - - - - - - - DUF11,SdrD_B k141_7589_1 765914.ThisiDRAFT_2784 4.7e-138 402.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1WW21@135613|Chromatiales 135613|Chromatiales M UTP-glucose-1-phosphate uridylyltransferase - - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_2007_1 765910.MARPU_12850 2.48e-117 346.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1WXIY@135613|Chromatiales 135613|Chromatiales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_22254_1 1469607.KK073769_gene6048 1.71e-23 104.0 COG1017@1|root,COG1357@1|root,COG1017@2|Bacteria,COG1357@2|Bacteria,1G3MG@1117|Cyanobacteria 1117|Cyanobacteria C Belongs to the globin family - - - - - - - - - - - - Globin,Pentapeptide k141_20809_1 1437882.AZRU01000104_gene3919 5.01e-19 85.9 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria,1YI8A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k141_20809_2 1562701.BBOF01000081_gene240 1.36e-65 221.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k141_13240_1 313603.FB2170_04840 4.06e-61 204.0 COG4315@1|root,COG4315@2|Bacteria,4NI3N@976|Bacteroidetes,1HYWK@117743|Flavobacteriia 976|Bacteroidetes S Secreted repeat of unknown function - - - - - - - - - - - - Lipoprotein_15 k141_1379_1 439496.RBY4I_3764 7.14e-73 235.0 COG0642@1|root,COG2205@2|Bacteria,1QV2U@1224|Proteobacteria,2TW9G@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase regB - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_19461_1 1051985.l11_00450 2.73e-17 82.8 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2VJ5U@28216|Betaproteobacteria,2KPGS@206351|Neisseriales 206351|Neisseriales S EamA-like transporter family rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_3462_1 870187.Thini_3152 5.41e-32 125.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein Ccs1 ResB - - - ko:K07399 - - - - ko00000 - - - ResB k141_3462_2 1255043.TVNIR_3745 5.36e-60 192.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1WYDI@135613|Chromatiales 135613|Chromatiales C PFAM Cytochrome c, class I - - - - - - - - - - - - Cytochrom_C k141_7590_2 1048983.EL17_10050 1.85e-26 105.0 COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_13924_1 998674.ATTE01000001_gene2588 1.9e-77 243.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,45ZMY@72273|Thiotrichales 72273|Thiotrichales F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_16010_1 439496.RBY4I_2673 5.14e-65 218.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria 28211|Alphaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_1380_1 1283300.ATXB01000001_gene2447 3.81e-22 92.4 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1XEIJ@135618|Methylococcales 135618|Methylococcales J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_22255_1 713586.KB900536_gene2461 4.32e-83 266.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_4849_1 1265502.KB905930_gene1433 1.08e-64 234.0 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4AJWE@80864|Comamonadaceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_7,PAS_8,PAS_9,PilJ,Response_reg k141_8956_1 713587.THITH_12010 3.46e-73 226.0 COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,1RYZ2@1236|Gammaproteobacteria,1WW9H@135613|Chromatiales 135613|Chromatiales C PFAM Nitrate reductase gamma subunit - - - - - - - - - - - - Nitrate_red_gam k141_8956_2 713587.THITH_12015 2.49e-147 429.0 COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales 135613|Chromatiales C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_17,Fer4_8 k141_4013_2 1234364.AMSF01000082_gene3012 2.36e-76 234.0 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XCE5@135614|Xanthomonadales 135614|Xanthomonadales E Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_5538_1 859657.RPSI07_mp1475 4.21e-146 412.0 COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,1K4BD@119060|Burkholderiaceae 28216|Betaproteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C k141_18773_1 697282.Mettu_2016 4.35e-23 93.6 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1XDKT@135618|Methylococcales 135618|Methylococcales G Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.2.1.109 ko:K08964 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_18773_2 686340.Metal_3599 2.36e-70 217.0 COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1XF09@135618|Methylococcales 135618|Methylococcales S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD - 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD k141_2008_1 391937.NA2_16957 3.82e-59 191.0 COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,43RRS@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Ndr family - - 3.1.1.24,4.1.1.44 ko:K01055,ko:K14727 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991,R03470 RC00825,RC00938 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,CMD k141_20810_1 870187.Thini_1825 1.64e-44 156.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,4607E@72273|Thiotrichales 72273|Thiotrichales E PFAM aminotransferase class-III argD - 2.6.1.11,2.6.1.13,2.6.1.17 ko:K00819,ko:K00821 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_20810_2 768671.ThimaDRAFT_4061 4.75e-102 304.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1WWPW@135613|Chromatiales 135613|Chromatiales E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_13925_1 367336.OM2255_06085 3.16e-102 315.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_4850_1 1278309.KB907107_gene1652 3.47e-137 394.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XHXP@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_2706_1 243233.MCA3076 2.3e-134 400.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1XEHX@135618|Methylococcales 135618|Methylococcales N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux k141_2706_2 243233.MCA3077 6.29e-73 228.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1XDJA@135618|Methylococcales 135618|Methylococcales S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_20032_1 1112216.JH594426_gene3799 1.51e-117 359.0 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2K2UN@204457|Sphingomonadales 204457|Sphingomonadales L Integrase core domain - - - - - - - - - - - - rve k141_5539_1 1415778.JQMM01000001_gene207 2.3e-40 140.0 COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,1J5SB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_2009_1 159450.NH14_15820 2.4e-07 48.1 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1K9A4@119060|Burkholderiaceae 28216|Betaproteobacteria K Cold shock protein cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_2009_2 377629.TERTU_1962 2.48e-39 133.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,2PNP2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S ATP-dependent Clp protease adaptor protein ClpS clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_13242_1 1049564.TevJSym_as00340 2.1e-29 115.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,1RMDQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT serine threonine protein kinase - - - - - - - - - - - - Pkinase k141_13242_2 795955.AFRW01000020_gene1911 2.19e-09 63.2 COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,1W93Y@1268|Micrococcaceae 201174|Actinobacteria T phosphatase - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - BofC_C,PP2C,PP2C_2 k141_7592_1 1288826.MSNKSG1_07418 1.02e-140 410.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,464G4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_4851_1 1121445.ATUZ01000001_gene162 8.44e-26 111.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MHE4@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3 k141_18774_1 519989.ECTPHS_06577 1.05e-36 135.0 COG5456@1|root,COG5456@2|Bacteria,1MYXM@1224|Proteobacteria,1S6WF@1236|Gammaproteobacteria,1WY96@135613|Chromatiales 135613|Chromatiales P FixH - - - - - - - - - - - - FixH k141_13926_1 1288826.MSNKSG1_13247 7.89e-180 508.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,1RR20@1236|Gammaproteobacteria,4656R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 k141_10423_1 1121403.AUCV01000001_gene716 3.97e-15 78.2 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHWA@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - ABC_sub_bind,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_3 k141_10423_2 332101.JIBU02000012_gene1021 7.88e-12 73.6 COG0840@1|root,COG0840@2|Bacteria,1V8NI@1239|Firmicutes,24EK9@186801|Clostridia,36HVX@31979|Clostridiaceae 186801|Clostridia NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_10423_3 575540.Isop_0274 8.26e-20 91.3 COG3222@1|root,COG3222@2|Bacteria,2J0B9@203682|Planctomycetes 203682|Planctomycetes S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 k141_16011_2 1278309.KB907105_gene1432 1.65e-224 625.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria,1XHH0@135619|Oceanospirillales 135619|Oceanospirillales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR k141_11131_1 1288826.MSNKSG1_07588 9.26e-65 211.0 COG2067@1|root,COG2067@2|Bacteria,1N0NZ@1224|Proteobacteria,1S0U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X k141_11131_2 1288826.MSNKSG1_07583 4.94e-245 674.0 2EKJK@1|root,33E9E@2|Bacteria,1NMXR@1224|Proteobacteria,1SHVJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Maltose operon periplasmic protein precursor (MalM) - - - - - - - - - - - - DUF4124,MalM k141_11131_3 1288826.MSNKSG1_07578 1.28e-229 634.0 COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria,466G6@72275|Alteromonadaceae 1236|Gammaproteobacteria G xylanase chitin deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_11131_4 1288826.MSNKSG1_07573 3.14e-145 410.0 COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAES@1236|Gammaproteobacteria,468CE@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG2214 DnaJ-class molecular chaperone - - - - - - - - - - - - DNAJ_related,DnaJ k141_11131_5 1288826.MSNKSG1_07568 3.22e-59 188.0 COG1309@1|root,COG1309@2|Bacteria,1RJ63@1224|Proteobacteria,1S8HV@1236|Gammaproteobacteria,46CGE@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N k141_8957_1 1179773.BN6_21030 0.000403 52.4 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4E1H0@85010|Pseudonocardiales 201174|Actinobacteria M TIGRFAM YD repeat protein - - - - - - - - - - - - PT-HINT,RHS_repeat k141_14522_1 558884.JRGM01000132_gene374 9.74e-96 295.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1Y3ZU@135624|Aeromonadales 135624|Aeromonadales T Bacterial regulatory protein, Fis family - - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_2010_1 1454004.AW11_00841 9.95e-18 79.3 COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,1KQQH@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Uncharacterized protein family, UPF0114 - - - - - - - - - - - - UPF0114 k141_5658_3 1288826.MSNKSG1_17356 1.09e-106 311.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S9TM@1236|Gammaproteobacteria,468Q1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_11919_1 1288826.MSNKSG1_00211 2.08e-68 223.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,4651D@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 DXP_synthase_N,Transket_pyr,Transketolase_C k141_11919_2 1288826.MSNKSG1_00216 4.61e-146 416.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,464WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004161,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - iPC815.YPO3176,iSFV_1184.SFV_0386 polyprenyl_synt k141_12618_1 1123257.AUFV01000016_gene3537 2.89e-24 101.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X41A@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_12618_2 1158762.KB898038_gene2075 7.64e-77 245.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1WX31@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_10522_1 1123279.ATUS01000001_gene1037 1.7e-22 94.4 COG2227@1|root,COG2227@2|Bacteria,1REWV@1224|Proteobacteria,1T1J3@1236|Gammaproteobacteria 1236|Gammaproteobacteria H methyltransferase ubiG3 - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_10522_2 187303.BN69_3477 3.92e-54 185.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases - - 1.1.99.31 ko:K15054 ko00627,ko01120,map00627,map01120 - R04160,R07664 RC00240 ko00000,ko00001,ko01000 - - - FMN_dh k141_21015_1 1479237.JMLY01000001_gene3356 4.44e-88 259.0 COG1942@1|root,COG1942@2|Bacteria,1RGXS@1224|Proteobacteria,1SI63@1236|Gammaproteobacteria,46C1S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative oxalocrotonate tautomerase enzyme - - - - - - - - - - - - Tautomerase_3 k141_20292_1 983545.Glaag_4250 1.61e-31 124.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,464BT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2206 HD-GYP domain - - - - - - - - - - - - DUF3391,HD,HD_5 k141_3541_1 1278309.KB907099_gene2519 3.03e-217 608.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RSQU@1236|Gammaproteobacteria,1XIYG@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_16087_1 1122201.AUAZ01000037_gene3847 1.78e-232 654.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,468GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_19578_1 1121935.AQXX01000018_gene3767 3.12e-65 219.0 COG1204@1|root,COG1204@2|Bacteria,1MW4Z@1224|Proteobacteria,1RXXN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DEAD DEAH box helicase - - - - - - - - - - - - DEAD,Helicase_C k141_13317_1 1232683.ADIMK_1393 4.31e-50 168.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,4648K@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_6323_1 95619.PM1_0209880 6.38e-47 172.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_12619_1 467661.RKLH11_1214 6.2e-29 108.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2V99R@28211|Alphaproteobacteria,3ZIMQ@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria K K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_12619_2 1045855.DSC_03820 7.28e-08 54.3 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1X42K@135614|Xanthomonadales 135614|Xanthomonadales EF Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_17461_1 644282.Deba_1764 4.34e-45 150.0 28NQ4@1|root,2ZBPU@2|Bacteria,1RCN1@1224|Proteobacteria,42QPC@68525|delta/epsilon subdivisions,2WMVS@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_53_2 1278309.KB907100_gene1948 5.62e-83 251.0 COG3440@1|root,COG3440@2|Bacteria,1NHIB@1224|Proteobacteria,1S546@1236|Gammaproteobacteria,1XPDU@135619|Oceanospirillales 135619|Oceanospirillales V Domain of unknown function (DUF3883) - - - - - - - - - - - - DUF3883 k141_11254_2 1453501.JELR01000001_gene3168 1.6e-176 530.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_4929_2 1217714.F975_01287 3.49e-43 162.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,3NMDC@468|Moraxellaceae 1236|Gammaproteobacteria T Histidine kinase narX - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3,PilJ k141_4929_3 1026882.MAMP_00527 1.5e-72 228.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_4929_4 1122201.AUAZ01000034_gene3515 2.46e-75 236.0 COG2199@1|root,COG2199@2|Bacteria,1RJGY@1224|Proteobacteria,1SBRV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - PAS,PAS_3 k141_4929_5 1232683.ADIMK_1430 1.34e-297 815.0 COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPIN@1236|Gammaproteobacteria,46CUP@72275|Alteromonadaceae 1236|Gammaproteobacteria P FAD-NAD(P)-binding - - 1.14.13.148 ko:K18277 ko00680,map00680 - R05623 RC00058 ko00000,ko00001,ko01000 - - - FMO-like k141_21653_1 1415756.JQMY01000001_gene459 3.47e-131 381.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2PCGI@252301|Oceanicola 28211|Alphaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_10523_1 553385.JEMF01000016_gene416 2.03e-57 194.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase - - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_7036_2 1415778.JQMM01000001_gene1975 4.27e-89 280.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1J4XI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_21016_1 765913.ThidrDRAFT_4145 9.88e-72 240.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWAU@135613|Chromatiales 135613|Chromatiales U Hydrophobe Amphiphile Efflux-1 (HAE1) - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_1453_1 314270.RB2083_2704 5.51e-16 79.3 COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria,3ZHKB@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria L COG3316 Transposase and inactivated derivatives - - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 k141_14005_2 396588.Tgr7_3147 1.91e-50 163.0 COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,1S98H@1236|Gammaproteobacteria,1X18F@135613|Chromatiales 135613|Chromatiales S Bacterial-like globin - - - ko:K06886 - - - - ko00000 - - - Bac_globin k141_14005_3 1235794.C811_01627 1.73e-12 70.9 COG0526@1|root,COG0526@2|Bacteria,2HVAY@201174|Actinobacteria,4CWKK@84998|Coriobacteriia 84998|Coriobacteriia CO Redoxin - - - - - - - - - - - - AhpC-TSA k141_9119_1 247639.MGP2080_08661 4.01e-42 145.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1J6M3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S aspartyl protease orf - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_9119_2 1500890.JQNL01000001_gene3338 6.2e-13 67.8 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1X3G8@135614|Xanthomonadales 135614|Xanthomonadales S Acyltransferase VL23_19915 - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_4228_1 1415754.JQMK01000002_gene2221 1.82e-94 281.0 COG2227@1|root,COG2227@2|Bacteria,1QYR4@1224|Proteobacteria,1T42Z@1236|Gammaproteobacteria,46D7G@72275|Alteromonadaceae 1236|Gammaproteobacteria H DREV methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_4228_2 357804.Ping_1502 1.93e-25 98.6 COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1SAAA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Rieske 2Fe-2S - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske k141_7745_1 631362.Thi970DRAFT_01601 4.68e-193 565.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales 135613|Chromatiales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_7745_2 1163408.UU9_03932 3.51e-180 516.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12980 - - - - ko00000,ko01005 - - - OMP_b-brl,Surface_Ag_2 k141_19579_1 644107.SL1157_1938 1.79e-64 224.0 COG0452@1|root,COG2105@1|root,COG0452@2|Bacteria,COG2105@2|Bacteria,1NZ4M@1224|Proteobacteria,2V21Z@28211|Alphaproteobacteria,4ND25@97050|Ruegeria 28211|Alphaproteobacteria H Phytochelatin synthase - - - - - - - - - - - - Ank_4,Flavoprotein,GGACT,Phytochelatin k141_11256_1 637905.SVI_3916 2.19e-55 181.0 COG0681@1|root,COG0681@2|Bacteria,1R7Z4@1224|Proteobacteria,1RX6N@1236|Gammaproteobacteria,2QARC@267890|Shewanellaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_13318_1 391593.RCCS2_09709 1.12e-15 73.2 COG1051@1|root,COG1051@2|Bacteria,1QYC2@1224|Proteobacteria,2TXN4@28211|Alphaproteobacteria,2P5AS@2433|Roseobacter 28211|Alphaproteobacteria F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_13318_2 1417296.U879_15835 2.47e-34 131.0 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria 28211|Alphaproteobacteria T response regulator - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HATPase_c_2,Response_reg,SpoIIE k141_17462_1 497321.C664_06173 1.96e-52 182.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,2KUU7@206389|Rhodocyclales 206389|Rhodocyclales S protease with the C-terminal PDZ domain - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_18881_1 1288826.MSNKSG1_04516 1e-196 550.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,467E4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family fieF - - - - - - - - - - - Cation_efflux,ZT_dimer k141_18881_2 1288826.MSNKSG1_04521 4.18e-237 653.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,464DT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 DHO_dh k141_18881_3 1288826.MSNKSG1_04526 3.21e-47 150.0 COG3130@1|root,COG3130@2|Bacteria,1N761@1224|Proteobacteria,1SCIC@1236|Gammaproteobacteria,468Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria J During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) rmf GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032055,GO:0032268,GO:0032269,GO:0033554,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043555,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 - ko:K03812 - - - - ko00000,ko03009 - - - RMF k141_18881_4 1288826.MSNKSG1_04531 0.0 1411.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,4657X@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_18881_5 1288826.MSNKSG1_04536 1.28e-135 385.0 2C3U6@1|root,348IH@2|Bacteria 2|Bacteria S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl k141_18881_6 1288826.MSNKSG1_04541 1.18e-107 310.0 COG0847@1|root,COG0847@2|Bacteria,1QY9K@1224|Proteobacteria,1T3MQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - k141_18881_7 1288826.MSNKSG1_04546 1.04e-306 836.0 COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria,46614@72275|Alteromonadaceae 1236|Gammaproteobacteria E M18 family aminopeptidase apeB GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 k141_18881_8 1288826.MSNKSG1_04551 5.97e-240 658.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,46554@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_18881_9 1288826.MSNKSG1_04556 5.34e-137 389.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 k141_18881_10 1288826.MSNKSG1_04561 3.79e-162 455.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,466GJ@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_18881_11 1288826.MSNKSG1_04566 1.06e-103 322.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,4654Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_16088_1 1328313.DS2_03660 1.96e-82 268.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,4662J@72275|Alteromonadaceae 1236|Gammaproteobacteria T CHASE2 - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_15442_1 1288826.MSNKSG1_05641 1.03e-291 805.0 COG0515@1|root,COG0515@2|Bacteria,1MWEY@1224|Proteobacteria,1RQHW@1236|Gammaproteobacteria,465AS@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase k141_12631_1 1001585.MDS_2333 4.29e-45 161.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,1YD20@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria MP PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_7770_1 396588.Tgr7_0817 7.25e-217 624.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales 135613|Chromatiales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_21041_2 1267535.KB906767_gene4225 3.62e-30 110.0 COG1324@1|root,COG1324@2|Bacteria,3Y5P7@57723|Acidobacteria 57723|Acidobacteria P CutA1 divalent ion tolerance protein - - - ko:K03926 - - - - ko00000 - - - CutA1 k141_7047_1 89187.ISM_01005 4.21e-09 56.2 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2UBS6@28211|Alphaproteobacteria,46P87@74030|Roseovarius 28211|Alphaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_15443_1 1305735.JAFT01000005_gene436 1.63e-128 376.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,2PCW6@252301|Oceanicola 28211|Alphaproteobacteria E Cys/Met metabolism PLP-dependent enzyme metZ GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_18205_1 2340.JV46_16820 7.77e-100 296.0 COG0730@1|root,COG0730@2|Bacteria,1QJ79@1224|Proteobacteria,1TH4W@1236|Gammaproteobacteria,1J7SI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_18205_2 1565129.JSFF01000012_gene559 2.41e-08 54.3 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,2Q8RD@267890|Shewanellaceae 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_7771_1 1049564.TevJSym_an00220 7.77e-26 104.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1J4J2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_16812_1 1198232.CYCME_1822 1.07e-156 450.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales 72273|Thiotrichales E Aminotransferase aspC2 - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_64_1 1535422.ND16A_1814 2.73e-44 163.0 COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Parallel beta-helix repeats - - - - - - - - - - - - Cu-oxidase_3 k141_13346_1 391624.OIHEL45_06430 4.65e-102 308.0 COG0439@1|root,COG0439@2|Bacteria,1R5XW@1224|Proteobacteria,2TU28@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Biotin carboxylase - - - - - - - - - - - - - k141_13346_2 83219.PM02_00030 0.00011 43.9 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria,3ZW6U@60136|Sulfitobacter 28211|Alphaproteobacteria E Orn/Lys/Arg decarboxylase, major domain - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C k141_10540_1 349124.Hhal_0864 4.87e-103 333.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_9826_1 105559.Nwat_2222 2.05e-48 164.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1WY90@135613|Chromatiales 135613|Chromatiales N Required for flagellar hook formation. May act as a scaffolding protein - - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_8437_1 105559.Nwat_0970 2.25e-40 142.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_8437_2 335283.Neut_1645 2.32e-31 114.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,373CA@32003|Nitrosomonadales 28216|Betaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_18901_1 1417296.U879_14795 3.19e-128 384.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C k141_20322_1 1033802.SSPSH_003047 6.28e-99 298.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG k141_14032_1 686340.Metal_0196 1.64e-09 61.6 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XENZ@135618|Methylococcales 135618|Methylococcales S ABC transporter C-terminal domain - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_14032_4 643562.Daes_3115 0.000107 44.7 COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales 28221|Deltaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_21042_1 314278.NB231_13021 1.52e-71 244.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales 135613|Chromatiales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_9138_1 1278309.KB907106_gene1257 7.05e-24 95.5 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XH9C@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_774_1 1288826.MSNKSG1_08513 4.61e-116 338.0 2E4B7@1|root,32Z6X@2|Bacteria,1N8XS@1224|Proteobacteria,1SENM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2846) - - - - - - - - - - - - DUF2846 k141_774_3 1288826.MSNKSG1_08503 9.98e-189 533.0 COG1028@1|root,COG1028@2|Bacteria,1MXRY@1224|Proteobacteria,1RZMB@1236|Gammaproteobacteria,46CH9@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_16813_1 367336.OM2255_10211 2.64e-75 242.0 COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,2TQKC@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1178 ABC-type Fe3 transport system permease component thiP - - ko:K02063 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - BPD_transp_1 k141_13347_1 765911.Thivi_4114 2.82e-89 284.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WVUN@135613|Chromatiales 135613|Chromatiales NT Signal transduction histidine kinase, subgroup, homodimeric - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_18902_1 376733.IT41_00240 1.23e-23 94.4 COG0685@1|root,COG0685@2|Bacteria,1RHDY@1224|Proteobacteria,2U4I0@28211|Alphaproteobacteria,2PYRU@265|Paracoccus 28211|Alphaproteobacteria E Methylene-tetrahydrofolate reductase C terminal - - - - - - - - - - - - MTHFR_C k141_21761_4 1278309.KB907101_gene712 5.93e-220 614.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XIRZ@135619|Oceanospirillales 135619|Oceanospirillales P Na H antiporter NhaD and related arsenite - - - - - - - - - - - - CitMHS k141_17601_1 375286.mma_2596 2.37e-42 145.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae 28216|Betaproteobacteria H Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_17601_2 1110502.TMO_0644 1.93e-48 171.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2U4S4@28211|Alphaproteobacteria,2JSJD@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_19010_1 1202962.KB907150_gene1913 2.28e-110 348.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family czcA - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_19010_2 572477.Alvin_0558 1.77e-66 221.0 COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1WYI5@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_19010_3 187272.Mlg_1558 6.28e-60 196.0 COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,1TKD5@1236|Gammaproteobacteria,1X1ZA@135613|Chromatiales 135613|Chromatiales C plastoquinol--plastocyanin reductase activity - - - - - - - - - - - - - k141_19010_4 1123393.KB891326_gene197 2.09e-170 492.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,1KT9P@119069|Hydrogenophilales 119069|Hydrogenophilales S Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - - - - - - - - - - FCSD-flav_bind,Pyr_redox_2,TAT_signal k141_12728_1 391589.RGAI101_3842 2.74e-130 376.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,2P12J@2433|Roseobacter 28211|Alphaproteobacteria C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs coxM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 k141_12728_2 631454.N177_1531 2.76e-31 120.0 COG3279@1|root,COG3300@1|root,COG3279@2|Bacteria,COG3300@2|Bacteria,1PXIQ@1224|Proteobacteria,2TT3B@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Carbon monoxide dehydrogenase operon C protein coxC GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K21696 - - - - ko00000,ko03000 - - - LytTR,MHYT k141_8544_1 1288826.MSNKSG1_03966 1.66e-291 826.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,464YY@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_8544_2 1288826.MSNKSG1_03961 1.02e-110 318.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,468P8@72275|Alteromonadaceae 1236|Gammaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins resA - - - - - - - - - - - AhpC-TSA k141_8544_3 351348.Maqu_0914 1.9e-63 195.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_8544_4 1288826.MSNKSG1_03946 1.28e-71 216.0 COG3308@1|root,COG3308@2|Bacteria,1N5UB@1224|Proteobacteria,1SAAJ@1236|Gammaproteobacteria,4693B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_8544_5 1288826.MSNKSG1_03941 2.36e-34 129.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,4662Z@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_2979_1 1123261.AXDW01000010_gene429 1.27e-89 276.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1X3EY@135614|Xanthomonadales 135614|Xanthomonadales M Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k141_10654_1 1288826.MSNKSG1_10748 8.58e-84 255.0 COG0640@1|root,COG4976@1|root,COG0640@2|Bacteria,COG4976@2|Bacteria,1NFSV@1224|Proteobacteria,1RQT6@1236|Gammaproteobacteria,464PH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_23,Methyltransf_31 k141_10654_2 1288826.MSNKSG1_10743 0.0 1333.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,4651B@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Transket_pyr,Transketolase_C,Transketolase_N k141_10654_3 1288826.MSNKSG1_10738 2.62e-88 267.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate epd GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043891,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048001,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.2.1.12,1.2.1.72 ko:K00134,ko:K03472 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 R01061,R01825 RC00149,RC00242 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - iYL1228.KPN_03356 Gp_dh_C,Gp_dh_N k141_873_1 1121459.AQXE01000006_gene201 1.34e-14 75.1 COG0475@1|root,COG0475@2|Bacteria,1R5QJ@1224|Proteobacteria,43DN6@68525|delta/epsilon subdivisions,2WTZY@28221|Deltaproteobacteria,2M8EB@213115|Desulfovibrionales 28221|Deltaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_873_3 1288826.MSNKSG1_04286 1.39e-07 52.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1S0SN@1236|Gammaproteobacteria,469DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB1 - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_13440_1 748658.KB907318_gene1008 3.88e-42 142.0 COG3439@1|root,COG3439@2|Bacteria,1NMII@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_13440_2 717772.THIAE_07020 5.98e-23 96.7 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,460K4@72273|Thiotrichales 72273|Thiotrichales C Rubredoxin - - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_1572_1 384676.PSEEN5549 5.89e-58 188.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 ATP-synt_A k141_1572_2 1163617.SCD_n03027 1.93e-06 51.2 2AFZM@1|root,3163K@2|Bacteria,1PWSR@1224|Proteobacteria,2VYPF@28216|Betaproteobacteria 28216|Betaproteobacteria S ATP synthase I chain - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I k141_1572_3 1137799.GZ78_22365 1.31e-68 217.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XHMA@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_14841_1 1387312.BAUS01000004_gene1683 2.36e-49 177.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,2KKUE@206350|Nitrosomonadales 206350|Nitrosomonadales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_5791_1 1237149.C900_01029 3.1e-118 358.0 COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,47JSM@768503|Cytophagia 976|Bacteroidetes M Penicillin-binding protein, dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_19011_1 713586.KB900536_gene1000 5.12e-86 268.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_2994_1 472759.Nhal_1498 3.2e-27 118.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales 135613|Chromatiales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA - 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_9917_1 95619.PM1_0201110 2.34e-238 671.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_13451_1 187272.Mlg_2763 1.84e-116 373.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_7870_1 1122197.ATWI01000011_gene434 4.62e-49 163.0 2B4XH@1|root,31ZRQ@2|Bacteria,1MYXK@1224|Proteobacteria,1S6BT@1236|Gammaproteobacteria,4685S@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19710_1 1121921.KB898708_gene1341 3.63e-32 125.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,2PMK9@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M PQQ-like domain bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_4384_1 1278309.KB907103_gene1138 1.14e-14 72.8 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XHAH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_4384_2 1278309.KB907103_gene1139 1.42e-269 740.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1XHB8@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_173_2 472759.Nhal_3945 1.26e-56 180.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k141_14856_1 1485544.JQKP01000005_gene393 8.22e-20 99.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,44V92@713636|Nitrosomonadales 28216|Betaproteobacteria N Belongs to the flagella basal body rod proteins family flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_21791_1 1415778.JQMM01000001_gene1276 4.19e-15 74.7 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1J4KH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0061 (SELO) family ydiU - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_21791_2 314292.VAS14_13544 8.51e-42 140.0 2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,1XXWT@135623|Vibrionales 135623|Vibrionales S HopJ type III effector protein - - - - - - - - - - - - HopJ k141_20440_1 1335757.SPICUR_09265 1.46e-22 97.8 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales 135613|Chromatiales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_20440_2 1384054.N790_08570 2.69e-44 159.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1X3DS@135614|Xanthomonadales 135614|Xanthomonadales CH Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol visC - - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3,SE k141_10675_1 1278309.KB907103_gene997 2.45e-49 167.0 COG2199@1|root,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,1S284@1236|Gammaproteobacteria,1XRT4@135619|Oceanospirillales 135619|Oceanospirillales T Protein of unknown function, DUF484 - - - - - - - - - - - - DUF484,GGDEF k141_10675_2 1278309.KB907103_gene998 7.44e-47 151.0 2EB0P@1|root,3351I@2|Bacteria,1NAEB@1224|Proteobacteria,1SCR3@1236|Gammaproteobacteria,1XKT0@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10675_3 1278309.KB907099_gene2567 1.2e-89 268.0 COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,1RR4T@1236|Gammaproteobacteria,1XK8A@135619|Oceanospirillales 135619|Oceanospirillales S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_10675_4 1278309.KB907103_gene1000 7.48e-182 514.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1XHRX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_18315_1 1288826.MSNKSG1_17546 2.26e-151 438.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,46A56@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_14141_1 331113.SNE_A11400 2.22e-21 94.4 2DNAV@1|root,32WHG@2|Bacteria 2|Bacteria S Yip1 domain - - - - - - - - - - - - Yip1 k141_17625_1 523791.Kkor_2620 1.51e-24 104.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1XHIS@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_17625_2 1565129.JSFF01000027_gene3298 5.76e-78 244.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,2Q8NK@267890|Shewanellaceae 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N k141_12755_2 713586.KB900536_gene2983 8.01e-59 191.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1WX0F@135613|Chromatiales 135613|Chromatiales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 k141_5817_1 379731.PST_2365 9.7e-70 222.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1Z122@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d k141_2258_1 1288826.MSNKSG1_12762 7.71e-262 721.0 COG5339@1|root,COG5339@2|Bacteria,1N902@1224|Proteobacteria 1224|Proteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_2258_2 1288826.MSNKSG1_12767 2.16e-222 629.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,464V1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iJN746.PP_5217 PP_kinase,PP_kinase_C,PP_kinase_N k141_4385_1 1353276.JADR01000009_gene1952 1.04e-161 464.0 COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HYW2@117743|Flavobacteriia 976|Bacteroidetes E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k141_21792_1 313606.M23134_03485 6.87e-53 176.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia 976|Bacteroidetes H Belongs to the PdxA family pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_19711_1 767817.Desgi_2859 0.000214 43.9 COG0515@1|root,COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,26097@186807|Peptococcaceae 186801|Clostridia T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISM_7TM,AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,Pkinase,Response_reg k141_11385_1 1206737.BAGF01000044_gene2709 4.82e-07 52.0 COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4FWAU@85025|Nocardiaceae 201174|Actinobacteria Q Thioesterase domain - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase k141_11385_2 748247.AZKH_3590 1.06e-46 163.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VK3J@28216|Betaproteobacteria,2KVS1@206389|Rhodocyclales 206389|Rhodocyclales E Diaminopimelate decarboxylase - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_175_1 1121271.AUCM01000007_gene3696 1.72e-37 137.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2U2B6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_16216_1 187272.Mlg_2440 1.24e-72 238.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales 135613|Chromatiales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_16216_2 1209072.ALBT01000061_gene983 3.31e-37 134.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,1FHHG@10|Cellvibrio 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_16216_3 686340.Metal_1717 3.47e-117 345.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XE2M@135618|Methylococcales 135618|Methylococcales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_14142_1 1333998.M2A_0747 1.83e-66 227.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,4BPGQ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_7872_1 1198232.CYCME_2433 5.37e-16 71.6 2DDNE@1|root,2ZINX@2|Bacteria,1PAK4@1224|Proteobacteria,1STKN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7872_2 1177181.T9A_02297 8.03e-48 162.0 COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,1S4AS@1236|Gammaproteobacteria,1XK6S@135619|Oceanospirillales 135619|Oceanospirillales T consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_12756_1 467661.RKLH11_1272 5.99e-38 135.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,3ZGKN@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_12756_2 571166.KI421509_gene3474 4.17e-34 129.0 COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VFZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the synthesis of activated sulfate cysC - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,HTH_24,PUA_2 k141_2995_1 1288826.MSNKSG1_01408 7.58e-122 352.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,466XD@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 NUDIX,NUDIX-like,zf-NADH-PPase k141_2995_2 1288826.MSNKSG1_01413 1.32e-58 188.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,467NW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_2496,iEC042_1314.EC042_4342,iECOK1_1307.ECOK1_4443,iECS88_1305.ECS88_4426,iPC815.YPO3909,iUMN146_1321.UM146_20110,iUTI89_1310.UTI89_C4562 Asp_Glu_race k141_17626_1 981369.JQMJ01000004_gene629 3.95e-16 82.4 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,2NF6F@228398|Streptacidiphilus 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 k141_4386_1 395019.Bmul_2677 6.96e-35 134.0 COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,1K0NW@119060|Burkholderiaceae 28216|Betaproteobacteria L Belongs to the methyltransferase superfamily rlmL - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 k141_9918_1 1288826.MSNKSG1_07428 3.01e-224 619.0 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,467WF@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF - - - - - - - - - - - Acetyltransf_10 k141_9918_2 1288826.MSNKSG1_07423 2.65e-245 675.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,464Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_5818_1 1278309.KB907106_gene1259 1.07e-90 291.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,1XKKF@135619|Oceanospirillales 135619|Oceanospirillales M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_19712_1 1121413.JMKT01000008_gene1605 1.54e-53 191.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WKJV@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,PA14 k141_21793_1 443144.GM21_2466 4.04e-05 53.1 28HYP@1|root,2Z842@2|Bacteria,1N96P@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_21793_2 1046714.AMRX01000003_gene30 2.14e-61 195.0 COG0110@1|root,COG0110@2|Bacteria,1RDQE@1224|Proteobacteria,1S3RJ@1236|Gammaproteobacteria,466XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (Isoleucine patch superfamily) - - - - - - - - - - - - Hexapep,Hexapep_2 k141_2996_1 1123393.KB891316_gene1237 6.51e-72 231.0 COG2199@1|root,COG3706@2|Bacteria,1N5SU@1224|Proteobacteria,2VTZT@28216|Betaproteobacteria 28216|Betaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_14859_1 40373.F991_03316 1.42e-50 164.0 COG1963@1|root,COG1963@2|Bacteria,1RKAF@1224|Proteobacteria,1S783@1236|Gammaproteobacteria,3NNFV@468|Moraxellaceae 1236|Gammaproteobacteria S Divergent PAP2 family - - - ko:K09775 - - - - ko00000 - - - DUF212 k141_14859_2 1122951.ATUE01000008_gene193 1.17e-33 125.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,3NMHE@468|Moraxellaceae 1236|Gammaproteobacteria H UbiA prenyltransferase family - - - - - - - - - - - - HAD,UbiA k141_16922_2 1278309.KB907111_gene3384 4.61e-171 481.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1XIC1@135619|Oceanospirillales 135619|Oceanospirillales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_16922_3 1278309.KB907111_gene3385 0.0 1063.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF k141_14143_1 367336.OM2255_12497 7.41e-64 204.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_342_1 323261.Noc_0087 1.9e-124 359.0 COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,1WYZ2@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF541) - - - ko:K09797 - - - - ko00000 - - - SIMPL k141_342_2 582402.Hbal_0446 4.86e-30 108.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,2U9J8@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_10811_1 717774.Marme_2197 1.07e-126 372.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_13565_1 1278309.KB907104_gene917 0.0 1638.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XH4B@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_3157_1 1117958.PE143B_0127635 9.68e-28 112.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase - - - ko:K20035 ko00920,map00920 - R11130 RC03363 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_3157_2 1278309.KB907099_gene2581 1.63e-262 727.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XHVH@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein-ubiquinone oxidoreductase etf - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 k141_19825_1 715451.ambt_21615 1.23e-46 155.0 2E487@1|root,32Z43@2|Bacteria,1N768@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_21963_1 580332.Slit_0150 2.8e-32 130.0 COG4585@1|root,COG4585@2|Bacteria,1R8DN@1224|Proteobacteria,2VPJ9@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 k141_21963_2 1479237.JMLY01000001_gene1806 3.41e-57 187.0 COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,1S3QG@1236|Gammaproteobacteria,468R3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_3812_1 713586.KB900536_gene2191 4.09e-29 115.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_3812_2 472759.Nhal_2365 3.17e-18 82.4 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1WWJP@135613|Chromatiales 135613|Chromatiales S Sterol-binding domain protein - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_2422_2 243159.AFE_2593 7.84e-25 99.0 2ECQ3@1|root,31692@2|Bacteria,1PX3E@1224|Proteobacteria,1T8SY@1236|Gammaproteobacteria,2NDD8@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - k141_2422_3 395494.Galf_2234 2.04e-29 114.0 COG3926@1|root,COG3926@2|Bacteria,1PVUY@1224|Proteobacteria,2WBHU@28216|Betaproteobacteria,44WKI@713636|Nitrosomonadales 28216|Betaproteobacteria S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k141_1758_1 376733.IT41_19785 8.23e-96 292.0 COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,2TRKA@28211|Alphaproteobacteria,2PYM1@265|Paracoccus 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - rve k141_6564_1 95619.PM1_0226410 5.45e-93 278.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Ubie_methyltran k141_5181_1 1232683.ADIMK_2114 5.6e-158 453.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RZG1@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_5181_2 1232683.ADIMK_1146 3.88e-72 226.0 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,1RNA4@1236|Gammaproteobacteria,466V1@72275|Alteromonadaceae 1236|Gammaproteobacteria C Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 vanB - 1.1.1.404 ko:K03863,ko:K21607 ko00361,ko00627,ko01100,ko01120,map00361,map00627,map01100,map01120 - R05274,R11585 RC00392,RC01533 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_9346_2 349124.Hhal_1930 4.2e-31 116.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12899_1 236097.ADG881_2129 1.94e-33 127.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1XQZT@135619|Oceanospirillales 135619|Oceanospirillales PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding k141_13566_1 1123400.KB904751_gene937 5.35e-14 71.6 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,45ZSX@72273|Thiotrichales 72273|Thiotrichales NU Type II IV secretion system protein - - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_13566_2 675817.VDA_003120 5.84e-43 153.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1XTCY@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsF GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_12197_1 384676.PSEEN4740 1.23e-16 92.4 COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_14249_1 472759.Nhal_3725 4.4e-76 238.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1WW0U@135613|Chromatiales 135613|Chromatiales O HflC and HflK could regulate a protease - - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_19197_1 1049564.TevJSym_au00070 2.15e-40 147.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,1JAAK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_344_1 1163617.SCD_n01123 3.47e-47 157.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria 28216|Betaproteobacteria S Haloacid dehalogenase-like hydrolase - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_3813_1 1278309.KB907102_gene88 3.48e-100 306.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1XI4T@135619|Oceanospirillales 135619|Oceanospirillales P iron ABC transporter permease - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_10064_1 351348.Maqu_0145 8.18e-15 75.1 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_5182_1 501479.ACNW01000088_gene2526 4.27e-06 47.8 COG1177@1|root,COG1177@2|Bacteria,1MV84@1224|Proteobacteria,2TTUV@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type spermidine putrescine transport system, permease component II MA20_32205 - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_5182_2 391589.RGAI101_2074 3.91e-79 242.0 COG1176@1|root,COG1176@2|Bacteria,1MW13@1224|Proteobacteria,2TR2S@28211|Alphaproteobacteria,2P3MB@2433|Roseobacter 28211|Alphaproteobacteria P ABC-type spermidine putrescine transport system, permease component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_20596_1 367336.OM2255_10700 5.31e-29 111.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_20596_2 633131.TR2A62_2961 1.51e-16 75.1 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L NYN domain MA20_36560 - - - - - - - - - - - NYN k141_18440_1 1278309.KB907101_gene791 1.07e-115 339.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1XIV6@135619|Oceanospirillales 135619|Oceanospirillales I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_12900_1 1123242.JH636437_gene5911 6.92e-19 87.0 COG3434@1|root,COG3434@2|Bacteria 2|Bacteria T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_12900_2 1232683.ADIMK_0354 3.13e-05 49.3 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,4649X@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_8070_2 1348657.M622_15050 4.87e-26 102.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,2KUPT@206389|Rhodocyclales 206389|Rhodocyclales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_12198_2 6669.EFX78318 5.18e-14 74.3 KOG4244@1|root,KOG4244@2759|Eukaryota,39T6N@33154|Opisthokonta,3BGJ2@33208|Metazoa,3CXV0@33213|Bilateria,41UY4@6656|Arthropoda 33208|Metazoa T Failed axon FAXC - - - - - - - - - - - GST_C_6,GST_N_4 k141_4543_1 387093.SUN_0975 5.9e-191 556.0 COG1835@1|root,COG5001@1|root,COG1835@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - DUF3365,EAL,GGDEF,PAS_9,dCache_3 k141_4543_2 1177154.Y5S_03013 3.49e-24 94.7 COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N k141_15669_1 926554.KI912671_gene402 1.04e-08 58.5 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k141_19826_1 367336.OM2255_06760 2.78e-43 151.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_19826_2 367336.OM2255_06755 3.47e-74 225.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the UPF0260 family MA20_15575 - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_19826_3 571166.KI421509_gene3461 2.79e-05 45.8 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_17056_1 491952.Mar181_3272 1.47e-63 207.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RRG3@1236|Gammaproteobacteria,1XJ7B@135619|Oceanospirillales 135619|Oceanospirillales G PFAM periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_17056_2 322710.Avin_03620 1.43e-131 381.0 COG0169@1|root,COG0169@2|Bacteria,1R48I@1224|Proteobacteria,1T16V@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_17056_3 1232683.ADIMK_3129 3.42e-132 379.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,466YY@72275|Alteromonadaceae 1236|Gammaproteobacteria G ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K02056,ko:K10441,ko:K10545 ko02010,map02010 M00212,M00215,M00221 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4 - - ABC_tran k141_10065_1 1042375.AFPL01000012_gene696 5.24e-17 75.1 COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,1S5AN@1236|Gammaproteobacteria,4699S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_10065_2 587753.EY04_18855 1.07e-12 68.2 28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,1RN0X@1236|Gammaproteobacteria 1236|Gammaproteobacteria M isomerase cti - - - - - - - - - - - CTI k141_10813_1 2340.JV46_27040 1.55e-66 209.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1JARK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_3158_2 765911.Thivi_0099 5.91e-97 293.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_14968_1 1026882.MAMP_00294 1.29e-113 340.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - DUF4113,IMS,IMS_C k141_13568_1 187272.Mlg_2860 2.06e-60 209.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales 135613|Chromatiales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_12901_1 398527.Bphyt_1341 4.14e-16 76.6 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1K1SN@119060|Burkholderiaceae 28216|Betaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_12901_2 765912.Thimo_0583 7.13e-26 101.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1WZFD@135613|Chromatiales 135613|Chromatiales U PFAM Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_11501_1 1288826.MSNKSG1_12172 2.81e-54 186.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,466IR@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain lapD - - - - - - - - - - - EAL,GGDEF,HAMP,LapD_MoxY_N k141_11501_2 1288826.MSNKSG1_12177 6.47e-264 730.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,46630@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,HDOD,Response_reg k141_12199_1 511062.GU3_09775 1.44e-88 281.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1Y43H@135624|Aeromonadales 135624|Aeromonadales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_5915_2 1479235.KK366039_gene1352 8.86e-39 150.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1RMQG@1236|Gammaproteobacteria,1XP8F@135619|Oceanospirillales 135619|Oceanospirillales K ANTAR - - - - - - - - - - - - ANTAR,NIT k141_14251_1 1122137.AQXF01000007_gene3582 1.27e-109 328.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the DNA photolyase family phrB GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_3814_1 1122621.ATZA01000006_gene747 2.2e-14 77.4 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1J0JM@117747|Sphingobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase todS_10 - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y k141_1759_1 1288826.MSNKSG1_06643 1.33e-214 615.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AM7@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT - - ko:K03556 - - - - ko00000,ko03000 - - - GerE,TPR_19,TPR_4,TPR_8 k141_8071_1 690597.JH730981_gene477 4.37e-27 102.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc k141_10066_1 1122201.AUAZ01000001_gene2338 4.18e-18 90.1 COG2304@1|root,COG2304@2|Bacteria,1QU09@1224|Proteobacteria,1T39R@1236|Gammaproteobacteria,46DBS@72275|Alteromonadaceae 1236|Gammaproteobacteria M oxidoreductase activity - - - - - - - - - - - - He_PIG,RHS_repeat k141_345_1 631362.Thi970DRAFT_00956 6.33e-71 218.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S - - - ko:K00184,ko:K21308 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 5.A.3 - - Fer4_11,Fer4_4,Fer4_7 k141_345_2 2340.JV46_27580 1.44e-124 383.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain ttrA - 1.8.5.5,1.8.5.6 ko:K08352,ko:K08357,ko:K21307 ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020 - R10149,R10150,R11487 RC00168,RC02823,RC03109 ko00000,ko00001,ko01000,ko02000 5.A.3.10,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal k141_20597_1 388413.ALPR1_20548 1.59e-55 194.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia 976|Bacteroidetes M Penicillin binding protein transpeptidase pbpB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_15671_1 1278307.KB906984_gene4435 1.56e-07 53.1 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,2QHTT@267894|Psychromonadaceae 1236|Gammaproteobacteria G HAD-hyrolase-like gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_19214_2 292415.Tbd_1651 5.06e-77 235.0 COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria 28216|Betaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 k141_19214_3 1297865.APJD01000007_gene1809 1.35e-07 52.4 COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TV0G@28211|Alphaproteobacteria,3K6XF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_7 k141_1046_1 314264.ROS217_17372 9.6e-71 238.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,46PWS@74030|Roseovarius 28211|Alphaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component dctM6 - - - - - - - - - - - DctM k141_5927_1 1182590.BN5_01870 1.6e-95 286.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1YDNH@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_17059_2 1278309.KB907110_gene3195 2.57e-242 671.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XHU4@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase k141_17059_3 1278309.KB907110_gene3194 1.03e-195 546.0 COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,1T34W@1236|Gammaproteobacteria,1XII6@135619|Oceanospirillales 135619|Oceanospirillales C Phosphate acetyl/butaryl transferase - - 2.3.1.8 ko:K00625 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydratas,PTA_PTB k141_21299_2 768671.ThimaDRAFT_0044 5.28e-41 143.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,1WXHS@135613|Chromatiales 135613|Chromatiales C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_19845_1 985054.JQEZ01000004_gene755 6.75e-27 105.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,4NA46@97050|Ruegeria 28211|Alphaproteobacteria S SCO1/SenC senC - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_19845_2 314256.OG2516_11161 8.88e-09 56.6 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2TSS0@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase regB - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_21972_1 1288826.MSNKSG1_03936 2.47e-205 572.0 28Q0R@1|root,2ZCJH@2|Bacteria,1RCAM@1224|Proteobacteria,1S3AM@1236|Gammaproteobacteria,4684M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3080) VP1478 - - - - - - - - - - - DUF3080 k141_21972_2 1288826.MSNKSG1_03941 0.0 1048.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,4662Z@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_1764_2 1288826.MSNKSG1_12962 7.7e-189 525.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,464UB@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_1764_3 1288826.MSNKSG1_12967 2.68e-132 375.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria 1224|Proteobacteria S ybak prolyl-trna synthetase associated - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_1764_4 1288826.MSNKSG1_12972 6.86e-294 804.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464US@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiF GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008682,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R06146,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0662,iBWG_1329.BWG_0533,iE2348C_1286.E2348C_0555,iECDH10B_1368.ECDH10B_0731,iECDH1ME8569_1439.ECDH1ME8569_0631,iETEC_1333.ETEC_0690,iEcDH1_1363.EcDH1_2964,iEcHS_1320.EcHS_A0709,iJO1366.b0662,iJR904.b0662,iSBO_1134.SBO_0526,iSbBS512_1146.SbBS512_E0585,iUMNK88_1353.UMNK88_700,iY75_1357.Y75_RS03450 FAD_binding_3,SE k141_1764_5 1288826.MSNKSG1_12977 2.77e-85 251.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,467BG@72275|Alteromonadaceae 1236|Gammaproteobacteria FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hinT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_18122_4 1288826.MSNKSG1_17990 2.21e-82 245.0 COG4726@1|root,COG4726@2|Bacteria 2|Bacteria NU Pilus assembly protein PilX mshP - - ko:K12286 - - - - ko00000,ko02044 - - - - k141_18122_5 675814.VIC_000965 1.21e-40 169.0 COG3210@1|root,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,1Y2F8@135623|Vibrionales 135623|Vibrionales U domain, Protein - - - ko:K12287 - - - - ko00000,ko02044 - - - Bactofilin,Laminin_G_3 k141_12546_1 1278309.KB907100_gene1824 1.48e-288 811.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XHBY@135619|Oceanospirillales 135619|Oceanospirillales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_12546_2 1278309.KB907100_gene1825 1.48e-56 176.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,1XKGU@135619|Oceanospirillales 135619|Oceanospirillales S deoxycytidine triphosphate deaminase - - - ko:K09948 - - - - ko00000 - - - DUF1244 k141_12546_3 1278309.KB907100_gene1826 3.21e-87 258.0 COG3018@1|root,COG3018@2|Bacteria,1N8R1@1224|Proteobacteria,1T0JQ@1236|Gammaproteobacteria,1XM3U@135619|Oceanospirillales 135619|Oceanospirillales S LPP20 lipoprotein - - - ko:K09860 - - - - ko00000 - - - LPP20 k141_12546_4 1278309.KB907100_gene1827 6.46e-128 367.0 COG5616@1|root,COG5616@2|Bacteria,1RFUP@1224|Proteobacteria,1RW7Q@1236|Gammaproteobacteria,1XJMA@135619|Oceanospirillales 135619|Oceanospirillales S cAMP biosynthetic process - - - - - - - - - - - - - k141_12546_5 1278309.KB907100_gene1828 3.6e-244 676.0 28KVI@1|root,2ZAC4@2|Bacteria,1RBAQ@1224|Proteobacteria,1S3C3@1236|Gammaproteobacteria,1XJ8S@135619|Oceanospirillales 135619|Oceanospirillales S Flagellar assembly protein T, middle domain - - - - - - - - - - - - FlgT_C,FlgT_M,FlgT_N k141_12546_6 710696.Intca_0913 4.33e-30 120.0 COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FG4H@85021|Intrasporangiaceae 201174|Actinobacteria Q Multicopper oxidase - - 1.3.3.5 ko:K08100 ko00860,ko01110,map00860,map01110 - R02394 RC01983 ko00000,ko00001,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_13244_1 89187.ISM_04765 2.97e-57 195.0 COG3898@1|root,COG3898@2|Bacteria,1P5RR@1224|Proteobacteria,2TT5Q@28211|Alphaproteobacteria,46PYQ@74030|Roseovarius 28211|Alphaproteobacteria S enzyme of heme biosynthesis lapB - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_19 k141_5577_1 765912.Thimo_1673 2.3e-82 261.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWJJ@135613|Chromatiales 135613|Chromatiales V PFAM ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_14638_1 765911.Thivi_3209 5.43e-101 306.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales 135613|Chromatiales P PFAM Citrate transporter - - - - - - - - - - - - CitMHS k141_2788_1 1195246.AGRI_03834 1.62e-43 170.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,46521@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_17425_1 671065.MetMK1DRAFT_00022740 8.81e-15 77.0 COG1912@1|root,arCOG04309@2157|Archaea,2XQIS@28889|Crenarchaeota 28889|Crenarchaeota S PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans k141_17425_2 713586.KB900536_gene2819 7.56e-163 470.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales 135613|Chromatiales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_4880_1 1123401.JHYQ01000047_gene163 1.63e-40 137.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,460J9@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_4880_2 1341157.RF007C_13205 0.000254 46.2 COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24H54@186801|Clostridia,3WJ4U@541000|Ruminococcaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - 5TM-5TMR_LYT,GGDEF k141_7669_1 629265.PMA4326_03589 4.06e-89 289.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1Z5N2@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_14639_1 1499967.BAYZ01000022_gene253 4.53e-44 158.0 COG4591@1|root,COG4591@2|Bacteria,2NQAR@2323|unclassified Bacteria 2|Bacteria M MacB-like periplasmic core domain VPA0559 - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_12547_1 1249627.D779_0882 2.18e-108 324.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1WVZ2@135613|Chromatiales 135613|Chromatiales E TIGRFAM glutamine synthetase, type I glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_10457_2 1500893.JQNB01000001_gene1269 2.32e-44 157.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1X432@135614|Xanthomonadales 135614|Xanthomonadales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_13941_1 1137799.GZ78_21080 7.89e-62 202.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales 135619|Oceanospirillales J SAM-dependent - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_9062_1 1294273.roselon_02560 1.31e-72 233.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2TS4G@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_16033_1 367336.OM2255_08516 2.34e-50 172.0 COG0665@1|root,COG0665@2|Bacteria,1MUUJ@1224|Proteobacteria,2TR9J@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) goxB - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_19518_1 767434.Fraau_1473 1.29e-37 132.0 2ADWQ@1|root,313NT@2|Bacteria,1QD2S@1224|Proteobacteria,1T8XV@1236|Gammaproteobacteria,1XBDC@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_19518_2 925984.E5AGG0_9CAUD 1.28e-21 88.2 4QD1J@10239|Viruses,4QW7G@35237|dsDNA viruses no RNA stage,4QQDR@28883|Caudovirales,4QI14@10662|Myoviridae 10662|Myoviridae S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k141_18123_1 713586.KB900536_gene2299 1.47e-182 525.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_18123_2 888064.HMPREF9088_1004 1.49e-15 81.6 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,4B0VW@81852|Enterococcaceae 91061|Bacilli P PBP superfamily domain pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_21605_2 1255043.TVNIR_0562 2.61e-37 133.0 COG4067@1|root,COG4067@2|Bacteria 2|Bacteria O ligase activity - - - - - - - - - - - - Zn_protease k141_21605_3 870187.Thini_4096 1.26e-59 195.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,460VD@72273|Thiotrichales 72273|Thiotrichales E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ - - ko:K06203 - - - - ko00000 - - - EI24 k141_6274_1 1122201.AUAZ01000038_gene1140 2.78e-180 513.0 COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,1RXX8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Alginate_exp k141_6274_2 247634.GPB2148_1643 8.86e-44 147.0 COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,1S98H@1236|Gammaproteobacteria,1J6JB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial-like globin - - - ko:K06886 - - - - ko00000 - - - Bac_globin k141_11852_1 90814.KL370892_gene2010 2.14e-72 226.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,462H0@72273|Thiotrichales 72273|Thiotrichales M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_11852_2 1211112.ALJC01000122_gene311 6.27e-12 65.1 COG0297@1|root,COG0297@2|Bacteria,1QV3H@1224|Proteobacteria,1T26X@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glycosyl Transferase wcaI GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K03208 - - - - ko00000 - GT4 - Glyco_trans_4_4,Glycos_transf_1 k141_7670_1 580332.Slit_0806 1.14e-107 320.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VNE4@28216|Betaproteobacteria,44WC3@713636|Nitrosomonadales 28216|Betaproteobacteria E Beta-eliminating lyase nifS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5,Rhodanese k141_4884_1 36033.XP_001643328.1 1.2e-08 60.1 COG0204@1|root,KOG2848@2759|Eukaryota,38GE5@33154|Opisthokonta,3NX4B@4751|Fungi,3QKXM@4890|Ascomycota,3RTIT@4891|Saccharomycetes,3RY14@4893|Saccharomycetaceae 4751|Fungi I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family - GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0031984,GO:0042171,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0090407,GO:0098827,GO:1901576 2.3.1.51 ko:K13509 ko00561,ko00564,ko01100,ko01110,ko04072,ko04975,map00561,map00564,map01100,map01110,map04072,map04975 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_6973_1 216595.PFLU_5069 3.27e-09 56.6 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1YM9M@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_6973_2 740709.A10D4_03190 1.63e-98 297.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,2QFBC@267893|Idiomarinaceae 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_12551_1 90814.KL370891_gene1283 2.35e-73 229.0 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_12551_2 754476.Q7A_877 2.2e-16 77.8 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales 72273|Thiotrichales L Exonuclease C-terminal sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_19524_1 1336233.JAEH01000037_gene9 7.71e-82 248.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,2Q92B@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 k141_15339_1 697282.Mettu_2584 2.71e-22 99.8 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XE56@135618|Methylococcales 135618|Methylococcales O TIGRFAM Cytochrome c-type biogenesis protein CcmI - - - ko:K02200 - - - - ko00000 - - - - k141_16733_1 546268.NEISUBOT_04523 8.95e-57 182.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,2KQUZ@206351|Neisseriales 206351|Neisseriales S Bacterial transferase hexapeptide repeat protein yrdA - - - - - - - - - - - Hexapep k141_16733_2 395493.BegalDRAFT_3002 9.46e-94 284.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales 72273|Thiotrichales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_1400_1 1266914.ATUK01000010_gene1220 5.95e-97 293.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales 135613|Chromatiales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_13251_1 571166.KI421509_gene1076 6.35e-135 390.0 COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TSBY@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG1410 Methionine synthase I cobalamin-binding domain acsE - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_11854_1 1502770.JQMG01000001_gene401 2.32e-56 184.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,2KKWM@206350|Nitrosomonadales 206350|Nitrosomonadales S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_11854_2 1479235.KK366039_gene1661 2.76e-42 145.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1XI7Z@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_8372_1 84531.JMTZ01000014_gene2804 5.41e-11 65.1 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1X3S1@135614|Xanthomonadales 135614|Xanthomonadales H receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_5578_1 1288826.MSNKSG1_16046 1.4e-310 854.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria CI Oxaloacetate oadA - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5346 Biotin_lipoyl,HMGL-like,PYC_OADA k141_5578_2 1288826.MSNKSG1_16051 8.52e-288 785.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,463ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_5578_3 1288826.MSNKSG1_16056 2.39e-275 754.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,465T4@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family pcaF - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_700_1 1122201.AUAZ01000023_gene3019 3.42e-53 175.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,468WK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B k141_14645_1 1461693.ATO10_14579 7.85e-74 233.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TQSZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_14645_2 314271.RB2654_08647 6.6e-63 199.0 COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,2TT79@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_20914_1 349124.Hhal_1431 9.41e-52 170.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales 135613|Chromatiales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_20914_2 697282.Mettu_2589 3.11e-93 279.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XE36@135618|Methylococcales 135618|Methylococcales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_20914_3 1123236.KB899378_gene1784 4.35e-87 261.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,4669C@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein Z012_09465 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_20914_4 314278.NB231_01424 9.79e-58 191.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1WW55@135613|Chromatiales 135613|Chromatiales DM peptidase - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_19525_1 314264.ROS217_02515 1.05e-56 198.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,46Q7U@74030|Roseovarius 28211|Alphaproteobacteria P COG2217 Cation transport ATPase actP - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS k141_3489_2 1278309.KB907111_gene3379 7.26e-232 650.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,1XIX7@135619|Oceanospirillales 135619|Oceanospirillales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases prpE - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_11855_1 1232683.ADIMK_0004 1.09e-74 233.0 COG0169@1|root,COG0169@2|Bacteria,1Q95E@1224|Proteobacteria,1S38H@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE2 - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_NADP,Shikimate_DH,Shikimate_dh_N k141_12552_1 930169.B5T_00457 1.24e-35 125.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1XPEX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_12552_2 1408445.JHXP01000011_gene858 7.4e-25 102.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1JCZQ@118969|Legionellales 118969|Legionellales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_9762_1 1278309.KB907108_gene1619 2.65e-42 144.0 COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,1S4IB@1236|Gammaproteobacteria,1XJR0@135619|Oceanospirillales 135619|Oceanospirillales T regulator - - - - - - - - - - - - Response_reg,Trans_reg_C k141_9762_2 1278309.KB907108_gene1618 4.01e-242 675.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1XJSU@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c k141_9762_3 1278309.KB907108_gene1617 2.24e-83 253.0 2FE9R@1|root,3469I@2|Bacteria,1P0B2@1224|Proteobacteria,1SSF8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9762_4 1278309.KB907108_gene1616 6.8e-130 378.0 COG1763@1|root,COG1763@2|Bacteria,1QUQC@1224|Proteobacteria,1S4HF@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mo-molybdopterin cofactor biosynthetic process - - - - - - - - - - - - - k141_13252_1 443143.GM18_1679 3.28e-66 218.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,43TZI@69541|Desulfuromonadales 28221|Deltaproteobacteria KT Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - HTH_8,PAS_4,PAS_9,Sigma54_activat k141_1401_1 404589.Anae109_0587 1.09e-19 89.0 COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,42VE6@68525|delta/epsilon subdivisions 1224|Proteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_1401_2 1121013.P873_11620 4.03e-06 48.5 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1X30F@135614|Xanthomonadales 135614|Xanthomonadales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_9066_1 1026882.MAMP_00233 1.04e-111 346.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,45ZWK@72273|Thiotrichales 72273|Thiotrichales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_11159_1 243233.MCA3037 1.2e-140 419.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XDR6@135618|Methylococcales 135618|Methylococcales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_6974_1 349163.Acry_1759 7.22e-05 44.3 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales 204441|Rhodospirillales S MazG nucleotide pyrophosphohydrolase domain mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_6974_2 519989.ECTPHS_06162 4.29e-58 193.0 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WVYJ@135613|Chromatiales 135613|Chromatiales T signal transduction protein - - - - - - - - - - - - HDOD k141_4187_1 1288826.MSNKSG1_14092 2.06e-58 188.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,464T8@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_4187_2 1288826.MSNKSG1_14097 7.54e-252 706.0 COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,464WG@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation ycaO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_10460_1 1288826.MSNKSG1_14337 1.99e-205 573.0 COG2421@1|root,COG2421@2|Bacteria,1MVRT@1224|Proteobacteria,1RQDU@1236|Gammaproteobacteria,4641U@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetamidase formamidase fmdA - 3.5.1.49 ko:K01455 ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200 - R00524 RC02432,RC02810 ko00000,ko00001,ko01000 - - - FmdA_AmdA k141_10460_2 1288826.MSNKSG1_14332 6.9e-84 247.0 COG2331@1|root,COG2331@2|Bacteria,1NABD@1224|Proteobacteria,1S97P@1236|Gammaproteobacteria,4681K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 k141_701_1 1388763.O165_021400 3.21e-95 294.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1YW2W@136845|Pseudomonas putida group 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_16735_1 1205753.A989_17568 1.16e-23 99.4 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_16735_2 1209072.ALBT01000038_gene2452 2.03e-44 149.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1FHFD@10|Cellvibrio 1236|Gammaproteobacteria L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_2790_1 1278309.KB907100_gene2007 6.77e-26 97.8 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1XKF8@135619|Oceanospirillales 135619|Oceanospirillales S 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase - - - - - - - - - - - - DUF971 k141_2790_2 1278309.KB907100_gene2008 1.08e-167 470.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales 135619|Oceanospirillales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_2790_3 207954.MED92_18038 7.33e-58 188.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1XKHK@135619|Oceanospirillales 135619|Oceanospirillales S SCP-2 sterol transfer family - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_2790_4 207954.MED92_18043 1.09e-81 243.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1XJHW@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_2790_5 1178482.BJB45_08945 8.13e-47 158.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria,1XJB7@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - FAA_hydrolase k141_20405_1 2340.JV46_10870 2.31e-117 362.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1J4DR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_5761_2 393595.ABO_2242 1.72e-28 115.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XHDI@135619|Oceanospirillales 135619|Oceanospirillales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_9189_1 1288826.MSNKSG1_08938 1.38e-138 393.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,464UP@72275|Alteromonadaceae 1236|Gammaproteobacteria S NIF3 (NGG1p interacting factor 3) ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - - - - - - - - - - NIF3 k141_11351_1 395493.BegalDRAFT_2181 2.47e-37 135.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,4625S@72273|Thiotrichales 72273|Thiotrichales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_15534_1 1121374.KB891589_gene65 5.06e-58 192.0 COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RM9J@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Filamentation induced by cAMP protein fic - - - - - - - - - - - - DUF4172,Fic k141_12009_1 1249627.D779_1402 2.53e-151 459.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1WW9S@135613|Chromatiales 135613|Chromatiales E Bacterial transglutaminase-like N-terminal - - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core k141_12009_2 1123228.AUIH01000073_gene3570 5.84e-31 123.0 28JFR@1|root,2Z99N@2|Bacteria,1R7C5@1224|Proteobacteria,1RZYU@1236|Gammaproteobacteria,1XJ6G@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_855_1 1288826.MSNKSG1_07778 1.23e-65 210.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,46DAS@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain macB - - ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - FtsX,MacB_PCD k141_855_2 1288826.MSNKSG1_07783 1.34e-153 434.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,46AMR@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_855_3 1288826.MSNKSG1_07788 7.92e-231 643.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,466RG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP k141_855_4 243231.GSU1269 1.66e-149 463.0 COG1470@1|root,COG5276@1|root,COG1470@2|Bacteria,COG5276@2|Bacteria,1NTT8@1224|Proteobacteria,42ZD4@68525|delta/epsilon subdivisions 1224|Proteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD k141_6421_1 633131.TR2A62_0787 4.73e-163 473.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria 28211|Alphaproteobacteria G 'PFAM Alpha amylase, catalytic aglA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C k141_14116_1 1123518.ARWI01000001_gene1725 2.26e-139 414.0 COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1MUM1@1224|Proteobacteria,1SZKS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Iron hydrogenase small subunit - - - - - - - - - - - - Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3 k141_21738_1 335541.Swol_1053 1.62e-43 158.0 COG4936@1|root,COG4936@2|Bacteria 2|Bacteria KT Sensory domain found in PocR - - - - - - - - - - - - HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg k141_3653_1 1220589.CD32_18270 1.55e-26 106.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3IYEZ@400634|Lysinibacillus 91061|Bacilli C NADPH quinone reductase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_3653_2 216591.BCAM1682 1.23e-48 171.0 COG0300@1|root,COG3193@1|root,COG0300@2|Bacteria,COG3193@2|Bacteria,1RGKZ@1224|Proteobacteria,2VTNK@28216|Betaproteobacteria,1K8AW@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_9886_1 999541.bgla_1g31070 2.22e-15 70.9 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,1K7M9@119060|Burkholderiaceae 28216|Betaproteobacteria K Belongs to the P(II) protein family glnB - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_9886_2 1095769.CAHF01000011_gene2273 1.27e-77 242.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,472J2@75682|Oxalobacteraceae 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_9886_3 322710.Avin_11940 3.47e-135 394.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_9886_4 675817.VDA_001324 1.25e-89 271.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XSY8@135623|Vibrionales 135623|Vibrionales S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_17581_1 1209072.ALBT01000058_gene917 1.34e-35 136.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1FH2K@10|Cellvibrio 1236|Gammaproteobacteria M Ami_3 amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_17581_2 34506.g2381 1.55e-14 73.2 COG0323@1|root,KOG1979@2759|Eukaryota,38E16@33154|Opisthokonta,3BA7K@33208|Metazoa,3CV1P@33213|Bilateria,40AKH@6231|Nematoda,1KUMG@119089|Chromadorea,40TFA@6236|Rhabditida 33208|Metazoa L DNA mismatch repair protein, C-terminal domain - GO:0003674,GO:0005488,GO:0005515 - ko:K08734 ko01524,ko03430,ko03460,ko05200,ko05210,ko05213,ko05226,map01524,map03430,map03460,map05200,map05210,map05213,map05226 M00295 - - ko00000,ko00001,ko00002,ko03400 - - - DNA_mis_repair,HATPase_c_3,Mlh1_C,MutL_C k141_19678_1 1121413.JMKT01000008_gene1075 3.07e-26 114.0 COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,42Q98@68525|delta/epsilon subdivisions,2WM5S@28221|Deltaproteobacteria,2MA0W@213115|Desulfovibrionales 28221|Deltaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2219) - - - - - - - - - - - - DUF2219 k141_10636_1 1128912.GMES_1540 5.25e-77 241.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,46A33@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_1549_1 519989.ECTPHS_10306 9.39e-78 236.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1WY1A@135613|Chromatiales 135613|Chromatiales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_7840_2 631362.Thi970DRAFT_03536 4.31e-101 325.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1WW84@135613|Chromatiales 135613|Chromatiales E Vitamin B12 dependent methionine synthase activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_3654_1 525897.Dbac_1784 5.92e-58 194.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2M8IG@213115|Desulfovibrionales 28221|Deltaproteobacteria M TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase - - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_2951_1 713587.THITH_17490 1.75e-16 75.9 2BU1D@1|root,32PA2@2|Bacteria,1N4TV@1224|Proteobacteria,1SBJ8@1236|Gammaproteobacteria,1WZ1H@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_134_1 69328.PVLB_17265 4.8e-82 253.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RZ2G@1236|Gammaproteobacteria 1236|Gammaproteobacteria I synthase - - 2.3.1.180 ko:K00648,ko:K22317 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iJN746.PP_4379 ACP_syn_III,ACP_syn_III_C k141_4353_1 706587.Desti_2692 5.46e-73 236.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MQ9M@213462|Syntrophobacterales 28221|Deltaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1259 ILVD_EDD k141_12010_1 319225.Plut_1317 2.27e-25 100.0 COG2050@1|root,COG2050@2|Bacteria,1FE5Q@1090|Chlorobi 1090|Chlorobi Q PFAM thioesterase superfamily protein - - 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT k141_10637_1 1173025.GEI7407_2908 2.09e-05 48.1 COG0084@1|root,COG0084@2|Bacteria,1G1SK@1117|Cyanobacteria,1H7FX@1150|Oscillatoriales 1117|Cyanobacteria L Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr) dtd3 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_10637_2 983545.Glaag_1774 9.35e-40 140.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,464BI@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_856_1 1038869.AXAN01000011_gene6634 5.01e-09 58.9 COG3203@1|root,COG3203@2|Bacteria,1R8YD@1224|Proteobacteria,2VNCH@28216|Betaproteobacteria,1K021@119060|Burkholderiaceae 28216|Betaproteobacteria M PFAM porin Gram-negative type - - - - - - - - - - - - Porin_4 k141_8521_1 1088721.NSU_3004 8.3e-65 213.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,2K114@204457|Sphingomonadales 204457|Sphingomonadales J Metallo-beta-lactamase superfamily domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_21740_1 765914.ThisiDRAFT_1338 2.13e-50 177.0 COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,1RQ1E@1236|Gammaproteobacteria,1WW44@135613|Chromatiales 135613|Chromatiales T nitrogen fixation negative regulator NifL - - - - - - - - - - - - HATPase_c,PAS,PAS_9 k141_19679_1 472759.Nhal_3897 2.04e-80 256.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales 135613|Chromatiales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_18987_1 1123514.KB905899_gene1275 4.87e-153 437.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,463X7@72273|Thiotrichales 72273|Thiotrichales G 6-phosphogluconate dehydrogenase, C-terminal domain - - - - - - - - - - - - 6PGD,NAD_binding_2 k141_18987_2 1123279.ATUS01000001_gene1222 1.44e-07 54.7 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1J4IF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf GO:0003674,GO:0003824,GO:0004345,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0009117,GO:0009372,GO:0009987,GO:0010699,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0023052,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - e_coli_core.b1852,iAF1260.b1852,iBWG_1329.BWG_1666,iE2348C_1286.E2348C_1977,iEC042_1314.EC042_2019,iECABU_c1320.ECABU_c21130,iECDH10B_1368.ECDH10B_1993,iECDH1ME8569_1439.ECDH1ME8569_1798,iECED1_1282.ECED1_2057,iECIAI39_1322.ECIAI39_1198,iECNA114_1301.ECNA114_1899,iECO26_1355.ECO26_2690,iECP_1309.ECP_1796,iECSF_1327.ECSF_1710,iECUMN_1333.ECUMN_2149,iECW_1372.ECW_m2026,iEKO11_1354.EKO11_1918,iEcDH1_1363.EcDH1_1789,iEcE24377_1341.EcE24377A_2082,iEcHS_1320.EcHS_A1944,iEcSMS35_1347.EcSMS35_1335,iEcolC_1368.EcolC_1780,iG2583_1286.G2583_2304,iJO1366.b1852,iJR904.b1852,iLF82_1304.LF82_3733,iNRG857_1313.NRG857_09280,iSDY_1059.SDY_1138,iWFL_1372.ECW_m2026,iY75_1357.Y75_RS09725,iYL1228.KPN_02367,ic_1306.c2265 G6PD_C,G6PD_N k141_16885_1 1288826.MSNKSG1_04191 9.12e-110 317.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1SEQD@1236|Gammaproteobacteria,46CTN@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III, chi subunit holC - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_16885_2 1288826.MSNKSG1_04196 0.0 967.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,463YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_16885_3 1288826.MSNKSG1_04201 7.6e-248 682.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,465H9@72275|Alteromonadaceae 1236|Gammaproteobacteria S permeases lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_16885_4 1288826.MSNKSG1_04206 5.92e-238 656.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,465SX@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_16885_5 1288826.MSNKSG1_04211 3.67e-118 338.0 COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,1SCCT@1236|Gammaproteobacteria,468CD@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein domain - - - - - - - - - - - - RDD k141_16885_6 1288826.MSNKSG1_04216 0.0 1692.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD k141_16885_7 1288826.MSNKSG1_04221 5.69e-181 510.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,465C7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_14809_1 1278309.KB907110_gene3215 1.14e-16 74.3 2DNT0@1|root,32YZR@2|Bacteria,1QX2U@1224|Proteobacteria,1T34V@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_14809_2 1278309.KB907110_gene3216 8.77e-173 484.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XJ0T@135619|Oceanospirillales 135619|Oceanospirillales U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_14809_3 207954.MED92_00869 8.59e-167 481.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XHZZ@135619|Oceanospirillales 135619|Oceanospirillales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_15537_1 1469245.JFBG01000013_gene1916 1.71e-05 47.4 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales 135613|Chromatiales C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_15537_2 870187.Thini_4244 5.73e-60 199.0 COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RMCU@1236|Gammaproteobacteria,461XW@72273|Thiotrichales 72273|Thiotrichales H Cobyrinic acid A,C-diamide - - 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 - - - CbiA,GATase_3 k141_14810_1 522306.CAP2UW1_2219 1.86e-51 172.0 COG2972@1|root,COG2972@2|Bacteria,1QYRK@1224|Proteobacteria,2WHJ2@28216|Betaproteobacteria 28216|Betaproteobacteria T Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365,HAMP k141_14810_2 614083.AWQR01000055_gene1978 3.81e-20 90.1 COG0515@1|root,COG2114@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,1PJRR@1224|Proteobacteria,2VHAU@28216|Betaproteobacteria,4AB4Y@80864|Comamonadaceae 28216|Betaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Pkinase k141_7844_1 1415755.JQLV01000001_gene1323 4.29e-20 92.4 COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1RXZW@1236|Gammaproteobacteria,1XJHG@135619|Oceanospirillales 135619|Oceanospirillales K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18 k141_14812_1 1123253.AUBD01000007_gene608 4.06e-91 293.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1X47W@135614|Xanthomonadales 135614|Xanthomonadales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_7845_1 1387312.BAUS01000004_gene1687 1.41e-55 185.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,2KKT6@206350|Nitrosomonadales 206350|Nitrosomonadales T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_7845_2 1177181.T9A_02072 2.31e-13 69.3 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XIUA@135619|Oceanospirillales 135619|Oceanospirillales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_14813_2 1237149.C900_02744 6.31e-15 75.1 COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolE_2 - - ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 - - FtsX,MacB_PCD k141_7846_1 388413.ALPR1_15924 5.44e-48 163.0 28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,47Q2P@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_6424_1 1120953.AUBH01000011_gene476 7.35e-13 64.3 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,4688I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_6424_2 391615.ABSJ01000039_gene1823 2.18e-52 174.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1J5Z0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_12706_1 314278.NB231_00994 4.83e-50 175.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales 135613|Chromatiales G pfam mofrl - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_3655_1 1123517.JOMR01000001_gene941 4.78e-170 492.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales 72273|Thiotrichales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_2952_1 317025.Tcr_2061 5.66e-75 233.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales 72273|Thiotrichales HJ Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_2952_2 1269813.ATUL01000025_gene2741 8.66e-52 169.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1WYD4@135613|Chromatiales 135613|Chromatiales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_11354_1 1165096.ARWF01000001_gene2027 1.23e-34 127.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KKH8@206350|Nitrosomonadales 206350|Nitrosomonadales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_5765_1 1049564.TevJSym_ar00060 9.96e-72 231.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1J4MK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_15538_1 225937.HP15_1263 2.32e-10 61.2 28Q0R@1|root,2ZCJH@2|Bacteria,1RCAM@1224|Proteobacteria,1S3AM@1236|Gammaproteobacteria,4684M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3080) VP1478 - - - - - - - - - - - DUF3080 k141_154_1 1278309.KB907104_gene917 1.98e-244 708.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XH4B@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_154_2 1278309.KB907104_gene916 2.3e-288 795.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales 135619|Oceanospirillales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_154_3 1278309.KB907104_gene914 3.45e-85 254.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1XK7D@135619|Oceanospirillales 135619|Oceanospirillales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 k141_14123_1 1205753.A989_12679 5.93e-07 50.4 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1X3S4@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_10652_1 1232683.ADIMK_3944 2.01e-61 220.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_2247_1 225937.HP15_2394 4.2e-99 288.0 COG1670@1|root,COG1670@2|Bacteria,1RKAB@1224|Proteobacteria,1S5YC@1236|Gammaproteobacteria,46CPN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 k141_2247_2 225937.HP15_2393 3.68e-137 394.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,464CM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2089 Sialic acid synthase neuB - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k141_13435_1 1249627.D779_1731 9.03e-80 256.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_16900_2 1255043.TVNIR_2991 1.86e-64 197.0 COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S765@1236|Gammaproteobacteria,1WYFD@135613|Chromatiales 135613|Chromatiales C ribulose bisphosphate carboxylase, small - - 4.1.1.39 ko:K01602 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_small k141_16900_3 1249627.D779_1741 7.32e-43 161.0 28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,1WW4J@135613|Chromatiales 135613|Chromatiales S Carboxysome shell peptide mid-region - - - - - - - - - - - - CsoS2_M k141_7147_1 713586.KB900536_gene2299 2.6e-128 384.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_4364_1 1288826.MSNKSG1_06988 8.44e-249 711.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_5783_2 1288298.rosmuc_03827 1.34e-24 102.0 COG3839@1|root,COG3839@2|Bacteria,1MX8G@1224|Proteobacteria,2TSXF@28211|Alphaproteobacteria,46NHQ@74030|Roseovarius 28211|Alphaproteobacteria P ABC transporter - - - ko:K17324 ko02010,map02010 M00607 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.35 - - ABC_tran,TOBE_2 k141_5783_3 314232.SKA53_08171 1.69e-17 82.8 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2P85H@245186|Loktanella 28211|Alphaproteobacteria C C-terminal domain of alpha-glycerophosphate oxidase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_16300_1 1123376.AUIU01000016_gene247 2.37e-12 67.4 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 wcaE GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - ko:K13683 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 k141_8030_1 95619.PM1_0200215 4.42e-09 60.8 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_8030_2 999141.GME_00735 2.6e-14 75.1 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XICE@135619|Oceanospirillales 135619|Oceanospirillales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_10029_1 1441629.PCH70_06200 3.97e-14 70.1 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1Z5W8@136849|Pseudomonas syringae group 1236|Gammaproteobacteria JM Nucleotidyl transferase - GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_10029_2 522306.CAP2UW1_2350 6.04e-21 93.2 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,2VNUH@28216|Betaproteobacteria 28216|Betaproteobacteria S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_13531_1 1163617.SCD_n00685 2.67e-36 143.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_15643_1 247633.GP2143_16536 1.13e-216 609.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_17756_1 1122201.AUAZ01000002_gene918 7.91e-14 70.5 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,466RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_17756_3 1278309.KB907103_gene1008 2.63e-48 159.0 COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,1SAW8@1236|Gammaproteobacteria,1XMIQ@135619|Oceanospirillales 135619|Oceanospirillales T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR k141_17756_4 1278309.KB907103_gene1009 7.12e-80 241.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1XHKF@135619|Oceanospirillales 135619|Oceanospirillales U MotA TolQ ExbB proton channel tolQ - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_17019_1 472759.Nhal_0924 4.55e-37 137.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1WW6N@135613|Chromatiales 135613|Chromatiales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_8656_1 388399.SSE37_19117 2.73e-54 171.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_12167_2 1288826.MSNKSG1_09783 1.79e-214 602.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,464QS@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_20577_1 314345.SPV1_00095 2.52e-35 139.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_2384_1 1517416.IDAT_08010 1.09e-154 444.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,2QF7X@267893|Idiomarinaceae 1236|Gammaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1427,iB21_1397.B21_00586,iBWG_1329.BWG_0499,iE2348C_1286.E2348C_0528,iEC55989_1330.EC55989_0620,iECABU_c1320.ECABU_c06820,iECBD_1354.ECBD_3023,iECB_1328.ECB_00597,iECDH10B_1368.ECDH10B_0589,iECDH1ME8569_1439.ECDH1ME8569_0597,iECD_1391.ECD_00597,iECED1_1282.ECED1_0624,iECH74115_1262.ECH74115_0716,iECIAI1_1343.ECIAI1_0611,iECIAI39_1322.ECIAI39_0603,iECNA114_1301.ECNA114_0567,iECO103_1326.ECO103_0635,iECO111_1330.ECO111_0658,iECO26_1355.ECO26_0702,iECOK1_1307.ECOK1_0638,iECP_1309.ECP_0658,iECS88_1305.ECS88_0669,iECSE_1348.ECSE_0695,iECSF_1327.ECSF_0567,iECSP_1301.ECSP_0681,iECUMN_1333.ECUMN_0720,iECW_1372.ECW_m0682,iECs_1301.ECs0666,iEKO11_1354.EKO11_3238,iETEC_1333.ETEC_0656,iEcDH1_1363.EcDH1_2998,iEcE24377_1341.EcE24377A_0652,iEcHS_1320.EcHS_A0679,iEcSMS35_1347.EcSMS35_0648,iEcolC_1368.EcolC_3017,iG2583_1286.G2583_0791,iJO1366.b0628,iLF82_1304.LF82_1199,iNRG857_1313.NRG857_02855,iSBO_1134.SBO_0492,iSDY_1059.SDY_0550,iSF_1195.SF0653,iSFxv_1172.SFxv_0720,iSSON_1240.SSON_0582,iS_1188.S0675,iSbBS512_1146.SbBS512_E0542,iUMN146_1321.UM146_14375,iUMNK88_1353.UMNK88_663,iUTI89_1310.UTI89_C0631,iWFL_1372.ECW_m0682,iY75_1357.Y75_RS03275,ic_1306.c0718 LIAS_N,Radical_SAM k141_21931_1 765912.Thimo_2695 6.49e-31 124.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k141_18422_1 1232683.ADIMK_0486 5.17e-55 190.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,4683Q@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the GSP D family cpaC - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N k141_18422_2 1207075.PputUW4_04075 1.15e-57 191.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF k141_18422_3 472759.Nhal_1418 1.6e-168 487.0 COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,1RZBX@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ATPase with chaperone activity - - - - - - - - - - - - - k141_12184_1 472759.Nhal_0146 2.23e-81 256.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales 135613|Chromatiales K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_4530_1 1278309.KB907099_gene2842 2.5e-156 440.0 COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,1XHFV@135619|Oceanospirillales 135619|Oceanospirillales S glutamine amidotransferase - - - - - - - - - - - - GATase_4 k141_4530_2 1278309.KB907099_gene2841 5.37e-71 216.0 COG1664@1|root,COG1664@2|Bacteria,1N14V@1224|Proteobacteria,1SAM9@1236|Gammaproteobacteria,1XKXR@135619|Oceanospirillales 135619|Oceanospirillales M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin k141_4530_3 1278309.KB907099_gene2840 4.88e-197 550.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1XIFQ@135619|Oceanospirillales 135619|Oceanospirillales M peptidase - - - - - - - - - - - - Peptidase_M23 k141_4530_4 1278309.KB907099_gene2839 1.95e-168 471.0 COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,1RZ6E@1236|Gammaproteobacteria,1XIZP@135619|Oceanospirillales 135619|Oceanospirillales S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 k141_4530_5 1278309.KB907099_gene2838 2.54e-76 238.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1RS3Z@1236|Gammaproteobacteria,1XKTC@135619|Oceanospirillales 135619|Oceanospirillales S Sodium Bile acid symporter family - - - - - - - - - - - - Mem_trans k141_3806_1 56780.SYN_02346 3.57e-61 197.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH k141_14244_1 1278309.KB907100_gene2173 2.08e-120 347.0 COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,1XIDX@135619|Oceanospirillales 135619|Oceanospirillales Q Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - - - - - - - - - - - - DJ-1_PfpI k141_9338_1 395961.Cyan7425_4217 8.58e-35 123.0 COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,3KI9U@43988|Cyanothece 1117|Cyanobacteria C Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_9338_2 477228.YO5_14820 1.52e-37 139.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1YZU7@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_21274_1 1033802.SSPSH_000095 1.63e-50 176.0 COG0392@1|root,COG0392@2|Bacteria,1R4IS@1224|Proteobacteria,1RYQY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_5908_1 1283300.ATXB01000001_gene1465 4.21e-69 233.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1XE8F@135618|Methylococcales 135618|Methylococcales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) - - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_6551_2 318586.Pden_2267 3.48e-30 107.0 COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,2PXMK@265|Paracoccus 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_6551_3 759362.KVU_2560 8.48e-09 57.0 COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria 28211|Alphaproteobacteria S rpsU-divergently transcribed protein cOQ9 - - ko:K18587 - - - - ko00000 - - - COQ9 k141_8049_1 1415778.JQMM01000001_gene1427 6.32e-29 112.0 COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria,1J6S5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Staphylococcal nuclease homologue - - - - - - - - - - - - SNase k141_8049_2 1328313.DS2_08273 6.25e-31 109.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,468J3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds the 23S rRNA rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_8681_1 1521187.JPIM01000057_gene2575 1.09e-12 73.2 COG0745@1|root,COG3829@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria 2|Bacteria T transcription factor binding - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,Response_reg k141_11485_1 367336.OM2255_06305 5.96e-63 211.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC-type multidrug transport system ATPase and permease msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_19184_1 765912.Thimo_1240 5.09e-23 98.6 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_14952_1 1288826.MSNKSG1_04071 1.46e-101 317.0 COG1842@1|root,COG4656@1|root,COG1842@2|Bacteria,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,4655V@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_14952_2 1288826.MSNKSG1_04066 8.43e-243 667.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,464JB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_14952_3 1288826.MSNKSG1_04061 1.59e-91 271.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,4672J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_3143_1 225937.HP15_3486 6.52e-24 99.4 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,46CPU@72275|Alteromonadaceae 1236|Gammaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase yhaE - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_3143_2 1278309.KB907101_gene792 1.27e-56 177.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1XKFS@135619|Oceanospirillales 135619|Oceanospirillales P part of a sulfur-relay system tusE - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_3143_3 1278309.KB907101_gene793 4.6e-48 155.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,1XMM8@135619|Oceanospirillales 135619|Oceanospirillales P DsrH like protein - - - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_3143_4 1278309.KB907101_gene794 2.51e-59 185.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1XM3I@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the DsrF TusC family - - - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_3143_5 498211.CJA_1664 2.31e-45 150.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1FIDC@10|Cellvibrio 1236|Gammaproteobacteria P DsrE/DsrF-like family tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_3143_6 1278309.KB907101_gene796 1.49e-131 376.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XJTV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the BI1 family - - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_3143_7 1278309.KB907101_gene797 3.76e-150 426.0 COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,1XJDP@135619|Oceanospirillales 135619|Oceanospirillales J synthase truC - 5.4.99.26 ko:K06175 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_2 k141_12185_1 575540.Isop_0320 4.24e-05 48.9 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,2J4Z7@203682|Planctomycetes 203682|Planctomycetes T SMART ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg k141_12185_2 273121.WS0850 1.12e-11 67.8 COG0642@1|root,COG0715@1|root,COG0784@1|root,COG0834@1|root,COG2198@1|root,COG0715@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T Histidine kinase - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - HATPase_c,HisKA,NIT,Response_reg k141_2407_2 1056820.KB900637_gene158 6.82e-07 52.4 COG0848@1|root,COG0848@2|Bacteria,1PCFE@1224|Proteobacteria,1SXFS@1236|Gammaproteobacteria,2PPE7@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_2407_3 983545.Glaag_2396 7.73e-14 78.2 COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,1S81P@1236|Gammaproteobacteria,46CQB@72275|Alteromonadaceae 1236|Gammaproteobacteria M TonB C terminal tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_2407_4 1298593.TOL_2764 1.5e-188 553.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,1XP3T@135619|Oceanospirillales 135619|Oceanospirillales P COG4774 Outer membrane receptor for monomeric catechols - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec k141_10043_1 1288826.MSNKSG1_09528 1.27e-136 389.0 COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,1S5Z3@1236|Gammaproteobacteria,46B6Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S PAP2 superfamily - - - - - - - - - - - - PAP2 k141_10043_2 1288826.MSNKSG1_09523 8.58e-289 789.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,464BH@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYL1228.KPN_03348 2-Hacid_dh,2-Hacid_dh_C,ACT k141_10043_3 1288826.MSNKSG1_09518 0.0 920.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4649Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases IV02_25675 - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_10043_4 1288826.MSNKSG1_09513 4.7e-108 313.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,4659I@72275|Alteromonadaceae 1236|Gammaproteobacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 k141_15658_1 1117319.PSPO_15973 1.01e-78 243.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,2PZKA@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_15658_2 930169.B5T_02319 4.83e-67 216.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1XJRF@135619|Oceanospirillales 135619|Oceanospirillales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_13549_1 765913.ThidrDRAFT_0813 1.95e-157 457.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_10805_1 1288826.MSNKSG1_14177 2.6e-136 391.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_10805_2 1288826.MSNKSG1_14182 3.28e-295 806.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family - - - - - - - - - - - - ELFV_dehydrog,ELFV_dehydrog_N k141_10805_3 1298593.TOL_0543 3.17e-38 128.0 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,1SDJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - k141_8050_1 1131553.JIBI01000083_gene2408 1.61e-78 246.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,2W0MI@28216|Betaproteobacteria,372WJ@32003|Nitrosomonadales 28216|Betaproteobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_7301_1 1500890.JQNL01000001_gene1462 1.84e-10 62.4 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1X70Z@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4 k141_7301_2 580332.Slit_0291 2.63e-112 331.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,44UYZ@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_8682_1 1232683.ADIMK_3945 6.51e-54 179.0 COG1737@1|root,COG1737@2|Bacteria,1R6J5@1224|Proteobacteria,1RQ8A@1236|Gammaproteobacteria,4670U@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - HTH_6,SIS k141_4531_2 556268.OFAG_00685 2.47e-85 268.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,476SM@75682|Oxalobacteraceae 28216|Betaproteobacteria O Peptidase family U32 C-terminal domain yhbU_1 - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_21951_1 1278309.KB907104_gene880 7.31e-292 798.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1XH5T@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_21951_2 1278309.KB907104_gene881 4.21e-67 213.0 COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,1XI9T@135619|Oceanospirillales 135619|Oceanospirillales P Voltage-dependent anion channel - - - - - - - - - - - - SLAC1 k141_17779_1 857087.Metme_4569 1.91e-46 151.0 2F8FM@1|root,340UB@2|Bacteria,1NXU1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_9340_1 1123261.AXDW01000002_gene1604 1.08e-30 120.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1X2Y5@135614|Xanthomonadales 135614|Xanthomonadales LU DNA processing protein DprA smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_9340_2 1411685.U062_01407 1.78e-10 63.9 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1J4FR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein containing LysM domain lysM - - - - - - - - - - - LysM k141_21275_1 243924.LT42_09440 1.92e-06 47.4 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU pilus assembly protein, PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_21275_2 519989.ECTPHS_03242 3.14e-46 166.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1WW0S@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, delta' - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_11486_1 998088.B565_0177 8.82e-99 313.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1Y426@135624|Aeromonadales 135624|Aeromonadales K Tex-like protein N-terminal domain - - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_8683_1 367336.OM2255_11245 2.15e-47 160.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_2408_1 1056512.D515_04447 5.35e-144 412.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,1XX4P@135623|Vibrionales 135623|Vibrionales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB k141_6553_1 243231.GSU1245 2.09e-31 124.0 COG0191@1|root,COG0191@2|Bacteria 2|Bacteria G fructose-bisphosphate aldolase activity - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase,OprB,SLH k141_3144_1 1288826.MSNKSG1_16571 7.37e-91 267.0 COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1S26B@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcription regulator that can specifically activate or repress expression of target genes slyA GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0043254,GO:0044087,GO:0044089,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141 - ko:K06075 - - - - ko00000,ko03000 - - - MarR,MarR_2 k141_3144_2 1288826.MSNKSG1_16576 5.52e-54 179.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_18430_1 1288826.MSNKSG1_10548 2.18e-45 154.0 COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,1S0IZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM NAD(P)H-binding - - - - - - - - - - - - Epimerase k141_18430_2 225937.HP15_2845 9.22e-53 171.0 28Z54@1|root,2ZKXF@2|Bacteria,1RAVB@1224|Proteobacteria,1S46P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - - k141_10806_1 1121396.KB893024_gene3899 1.45e-111 332.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2MIIQ@213118|Desulfobacterales 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family arnB - - - - - - - - - - - DegT_DnrJ_EryC1 k141_17780_1 1122137.AQXF01000002_gene132 4.85e-125 388.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_13550_1 395493.BegalDRAFT_2995 1.37e-51 171.0 2A8YE@1|root,30Y24@2|Bacteria,1QBAG@1224|Proteobacteria,1T6V4@1236|Gammaproteobacteria,463E0@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_8684_1 523791.Kkor_1481 3.3e-23 94.7 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales 135619|Oceanospirillales S colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V k141_519_1 313589.JNB_13793 5.22e-07 56.2 COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4FFFM@85021|Intrasporangiaceae 201174|Actinobacteria G Inosose dehydratase - - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 k141_5404_1 1288826.MSNKSG1_05601 4.93e-256 721.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,469QF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_17215_1 1278309.KB907106_gene1301 2e-211 603.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHCB@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_17215_2 1278309.KB907106_gene1302 2.04e-120 350.0 COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,1XJH6@135619|Oceanospirillales 135619|Oceanospirillales S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_17215_3 1278309.KB907106_gene1303 1.25e-179 501.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1XH7U@135619|Oceanospirillales 135619|Oceanospirillales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_17215_4 1278309.KB907106_gene1305 9.09e-91 271.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XHH5@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_7484_1 1323663.AROI01000023_gene1493 1.09e-108 318.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria 1224|Proteobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_13766_2 95619.PM1_0218195 8.72e-34 118.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 k141_19981_1 349521.HCH_01823 5.64e-55 186.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XI4B@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF k141_19981_2 1216007.AOPM01000004_gene2492 6e-48 173.0 COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,2Q0YS@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria MP PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - OmpA,PBP_like_2 k141_18600_1 1288826.MSNKSG1_01458 2.16e-266 728.0 COG3239@1|root,COG3239@2|Bacteria,1R3XI@1224|Proteobacteria,1RRM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_18600_2 1288826.MSNKSG1_01453 3.15e-151 426.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,466GT@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain tcsR - - - - - - - - - - - GerE,Response_reg k141_18600_3 1288826.MSNKSG1_01448 0.0 1322.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,4641P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - iE2348C_1286.E2348C_4392,iYL1228.KPN_04478 ACAS_N,AMP-binding,AMP-binding_C k141_18600_4 1288826.MSNKSG1_01443 0.0 964.0 COG3320@1|root,COG3320@2|Bacteria,1R7K7@1224|Proteobacteria,1RY3K@1236|Gammaproteobacteria,46AEX@72275|Alteromonadaceae 1236|Gammaproteobacteria Q dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - 1.2.1.84 ko:K13356 ko00073,ko04146,ko04212,map00073,map04146,map04212 - R09470 RC00004 ko00000,ko00001,ko01000 - - - NAD_binding_4,Sterile k141_18600_5 1288826.MSNKSG1_01438 8.83e-286 784.0 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RQSP@1236|Gammaproteobacteria,46CPM@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG0455 ATPases involved in chromosome partitioning - - - ko:K04562 - - - - ko00000,ko02035 - - - AAA_31,ParA k141_18600_6 1288826.MSNKSG1_01433 0.0 1192.0 COG1639@1|root,COG2203@1|root,COG3852@1|root,COG1639@2|Bacteria,COG2203@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,1RYHZ@1236|Gammaproteobacteria,46CHK@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction - - - - - - - - - - - - GAF,GAF_3,HATPase_c,HDOD k141_18600_7 1288826.MSNKSG1_01428 4.12e-108 331.0 COG0745@1|root,COG5001@1|root,COG0745@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4643S@72275|Alteromonadaceae 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_15107_1 1131814.JAFO01000001_gene302 6.35e-47 168.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR1S@28211|Alphaproteobacteria,3F0AY@335928|Xanthobacteraceae 28211|Alphaproteobacteria T Cache 3/Cache 2 fusion domain - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,sCache_3_3 k141_15107_2 1288298.rosmuc_02443 2.82e-77 234.0 28NIR@1|root,2ZBK2@2|Bacteria,1RAAF@1224|Proteobacteria,2U5XR@28211|Alphaproteobacteria,46Q0N@74030|Roseovarius 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12397_1 1268635.Loa_02269 9.31e-135 392.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1JCV7@118969|Legionellales 118969|Legionellales NU Type II/IV secretion system protein uptC - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_16519_1 240292.Ava_1936 2.21e-71 221.0 COG3576@1|root,COG3576@2|Bacteria,1G5D9@1117|Cyanobacteria,1HKRX@1161|Nostocales 1117|Cyanobacteria S PFAM Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx k141_16519_2 396588.Tgr7_2982 1.27e-72 228.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales 135613|Chromatiales G PFAM Fructosamine - - - - - - - - - - - - Fructosamin_kin k141_6032_1 1278309.KB907099_gene3134 2.32e-95 284.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria 1236|Gammaproteobacteria G protein conserved in bacteria - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF455 k141_6032_2 1278309.KB907099_gene3133 1.41e-108 314.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,1XK4M@135619|Oceanospirillales 135619|Oceanospirillales S YaeQ - - - - - - - - - - - - YaeQ k141_6032_3 1278309.KB907099_gene3132 9.25e-43 140.0 COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,1SCG7@1236|Gammaproteobacteria,1XM2J@135619|Oceanospirillales 135619|Oceanospirillales S Fe-S-cluster oxidoreductase - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_6032_4 1278309.KB907099_gene3131 7.06e-217 603.0 COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1XIBU@135619|Oceanospirillales 135619|Oceanospirillales S nucleoid-associated protein - - - ko:K06899 - - - - ko00000,ko03036 - - - NA37 k141_3950_2 1278309.KB907099_gene2454 3.76e-70 212.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XK2I@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the glutaredoxin family. Monothiol subfamily ydhD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin k141_3950_3 1278309.KB907099_gene2453 2.91e-259 713.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XH48@135619|Oceanospirillales 135619|Oceanospirillales E acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_2569_1 666685.R2APBS1_3489 2.74e-19 84.7 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1X305@135614|Xanthomonadales 135614|Xanthomonadales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 k141_2569_2 1122179.KB890426_gene4010 7.96e-11 64.7 COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia 976|Bacteroidetes E COG2755 Lysophospholipase L1 and related - - - - - - - - - - - - Lipase_GDSL_2 k141_17216_1 493475.GARC_0044 2.97e-61 193.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,1T62V@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA2 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_520_1 1278309.KB907103_gene1029 1.45e-115 352.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XH36@135619|Oceanospirillales 135619|Oceanospirillales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_6033_1 519989.ECTPHS_04708 3.31e-90 278.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1WVYU@135613|Chromatiales 135613|Chromatiales N ATPase FliI YscN family - - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_7485_1 351348.Maqu_0209 2.73e-146 422.0 COG0582@1|root,COG0582@2|Bacteria,1R5TQ@1224|Proteobacteria,1RY85@1236|Gammaproteobacteria,46AI6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Phage integrase family protein - - - - - - - - - - - - Phage_integrase k141_7485_2 1046724.KB889952_gene2063 3.54e-28 113.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria,46AHK@72275|Alteromonadaceae 1236|Gammaproteobacteria L Putative phage integrase - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_integrase k141_13767_1 1123392.AQWL01000006_gene695 2.41e-34 137.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KS2S@119069|Hydrogenophilales 119069|Hydrogenophilales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_13767_2 391615.ABSJ01000001_gene421 1.76e-28 109.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1JB8P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin k141_11646_1 1148.1653137 2.64e-25 109.0 COG1215@1|root,COG1215@2|Bacteria,1G3C9@1117|Cyanobacteria 1117|Cyanobacteria M glycosyl transferase - - - - - - - - - - - - Glycos_transf_2 k141_11646_2 338963.Pcar_2251 1.38e-104 316.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase uxs - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_11646_3 653733.Selin_1933 6.72e-56 179.0 COG1974@1|root,COG1974@2|Bacteria 2|Bacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair umuD - 3.4.21.88 ko:K01356,ko:K03503 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - HTH_3,Peptidase_S24 k141_11646_4 1278309.KB907111_gene3389 1.84e-257 711.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMT1@1236|Gammaproteobacteria,1XH3E@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase umuC - - ko:K03502 - - - - ko00000,ko03400 - - - DUF4113,IMS,IMS_C,IMS_HHH k141_2570_1 643648.Slip_1606 7.77e-56 184.0 COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,24DFX@186801|Clostridia,42KKU@68298|Syntrophomonadaceae 186801|Clostridia L IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 k141_6034_1 207954.MED92_04934 2.26e-113 333.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RR72@1236|Gammaproteobacteria,1XHDP@135619|Oceanospirillales 135619|Oceanospirillales G TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP k141_18602_1 1226994.AMZB01000098_gene1234 8.74e-37 134.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1YD15@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_15875_1 1288826.MSNKSG1_08918 1.85e-58 197.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,4645D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) aidA - - - - - - - - - - - DUF1302 k141_15875_2 1288826.MSNKSG1_08923 5.82e-144 414.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_537_2 640081.Dsui_0894 2.03e-128 408.0 COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales 206389|Rhodocyclales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,Response_reg k141_3962_2 1028800.RG540_CH13770 3.61e-48 165.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria,4BJMF@82115|Rhizobiaceae 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k141_4727_1 1278309.KB907100_gene2134 6.77e-81 252.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XH48@135619|Oceanospirillales 135619|Oceanospirillales E acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.17,2.6.1.81 ko:K00821,ko:K00840 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04217,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_4727_2 1278309.KB907100_gene2135 1.22e-154 446.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,1RNIW@1236|Gammaproteobacteria,1XHPY@135619|Oceanospirillales 135619|Oceanospirillales E Acetylornithine deacetylase - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_6053_1 314285.KT71_09502 2.44e-147 426.0 COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,1J9DV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase sqr - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_12418_1 1430440.MGMSRv2_4000 1.31e-66 218.0 COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2U13I@28211|Alphaproteobacteria,2JQVM@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo k141_15123_1 1238182.C882_3486 1.23e-37 144.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JRBS@204441|Rhodospirillales 204441|Rhodospirillales T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_9497_1 1280681.AUJZ01000055_gene95 1.61e-07 55.1 2ED6K@1|root,3373A@2|Bacteria,1VI2S@1239|Firmicutes 1239|Firmicutes S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - - - - - - - - - - - k141_1255_2 640081.Dsui_0044 6.3e-75 233.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,2KUPT@206389|Rhodocyclales 206389|Rhodocyclales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_11002_1 713587.THITH_08660 5.12e-30 119.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_13092_1 713586.KB900536_gene1344 2.14e-31 119.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1WWBW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_13092_2 498211.CJA_3204 1.45e-49 166.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1FGIH@10|Cellvibrio 1236|Gammaproteobacteria S Multi-copper polyphenol oxidoreductase laccase yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 k141_18625_1 367336.OM2255_06085 2.36e-93 291.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_21457_1 935261.JAGL01000004_gene962 1.13e-35 137.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,43HWM@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S AFG1-like ATPase zapE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_5418_2 1163617.SCD_n02290 7.39e-125 406.0 COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg k141_13788_1 1121935.AQXX01000118_gene4942 1.65e-75 232.0 COG4430@1|root,COG4430@2|Bacteria,1RJGC@1224|Proteobacteria,1S853@1236|Gammaproteobacteria,1XK0S@135619|Oceanospirillales 135619|Oceanospirillales S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA k141_10263_1 2340.JV46_16430 2.93e-22 90.5 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,1J71Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - - - - - - - - - - Rieske k141_10263_2 1469245.JFBG01000023_gene1223 3.25e-33 119.0 COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the bacterial histone-like protein family VL23_14575 - - - - - - - - - - - Bac_DNA_binding k141_3329_1 314278.NB231_00760 4.7e-149 427.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1WWUX@135613|Chromatiales 135613|Chromatiales P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_3329_2 1163617.SCD_n00928 1.66e-15 75.5 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_6054_1 29581.BW37_05039 3.82e-48 177.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,47606@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_3,PAS_8,PAS_9,Response_reg k141_3963_2 388413.ALPR1_19563 7.26e-92 272.0 COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,47KSN@768503|Cytophagia 976|Bacteroidetes J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C k141_11003_1 748658.KB907317_gene307 1.3e-31 119.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1WWVK@135613|Chromatiales 135613|Chromatiales N Role in flagellar biosynthesis - - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_11003_2 1238450.VIBNISOn1_1090025 1.24e-12 68.6 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XTM7@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_18626_2 467661.RKLH11_3009 2.93e-51 173.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,3ZGPT@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_11666_1 1120953.AUBH01000009_gene2 1.22e-53 180.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,468IR@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial transcription activator, effector binding domain - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_17990_1 1278309.KB907112_gene3339 5e-183 519.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_1256_1 395494.Galf_1707 3.67e-30 110.0 COG0346@1|root,COG0346@2|Bacteria,1PVYI@1224|Proteobacteria,2VVCZ@28216|Betaproteobacteria,44VXU@713636|Nitrosomonadales 28216|Betaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_1256_2 1123368.AUIS01000020_gene1085 1.1e-28 115.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,2NBVF@225057|Acidithiobacillales 225057|Acidithiobacillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_19363_2 1278309.KB907099_gene3026 1.96e-38 129.0 COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria,1XM0U@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09954 - - - - ko00000 - - - QSregVF_b k141_3330_1 391593.RCCS2_02610 9.53e-104 320.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,2P12T@2433|Roseobacter 28211|Alphaproteobacteria H Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_13094_1 666685.R2APBS1_0205 2.35e-72 233.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the DNA photolyase family phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_13094_2 237368.SCABRO_03545 7.34e-06 45.8 COG2138@1|root,COG2138@2|Bacteria,2J082@203682|Planctomycetes 203682|Planctomycetes H Cobalamin (Vitamin B12) biosynthesis CbiX protein - - - - - - - - - - - - CbiX k141_22117_1 1288826.MSNKSG1_15581 4.61e-250 705.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,465ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_22117_2 270374.MELB17_23025 1.43e-62 196.0 COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,1S6D1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_12419_1 267608.RSp1344 1.79e-17 77.4 COG1977@1|root,COG1977@2|Bacteria,1N4M4@1224|Proteobacteria,2VUTF@28216|Betaproteobacteria,1K8VV@119060|Burkholderiaceae 28216|Betaproteobacteria H ThiS family - - - - - - - - - - - - ThiS k141_12419_2 290397.Adeh_2223 8.87e-117 348.0 COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,432XE@68525|delta/epsilon subdivisions,2WYHS@28221|Deltaproteobacteria,2YU0E@29|Myxococcales 28221|Deltaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - - k141_15220_2 1348635.BBJY01000004_gene3124 3.83e-08 51.6 2EGA9@1|root,33A23@2|Bacteria,1NI0T@1224|Proteobacteria,1SH37@1236|Gammaproteobacteria,1XZKP@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_14539_1 1278309.KB907101_gene305 5.65e-10 57.0 COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,1XMAC@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CYTH k141_14539_2 1278309.KB907101_gene306 0.0 1303.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XHBT@135619|Oceanospirillales 135619|Oceanospirillales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_14539_3 1278309.KB907101_gene307 4.8e-232 646.0 COG1639@1|root,COG1639@2|Bacteria,1R6YN@1224|Proteobacteria,1S0UQ@1236|Gammaproteobacteria,1XJ3E@135619|Oceanospirillales 135619|Oceanospirillales T HDOD domain - - - - - - - - - - - - HDOD k141_14539_4 1278309.KB907101_gene308 1.77e-240 663.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,1XI2K@135619|Oceanospirillales 135619|Oceanospirillales J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA - 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_14539_5 1278309.KB907101_gene309 0.0 1432.0 COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XIGR@135619|Oceanospirillales 135619|Oceanospirillales I Acyltransferase - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,MFS_1 k141_17378_1 1453501.JELR01000002_gene1334 6.59e-42 157.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae 1236|Gammaproteobacteria E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k141_9002_1 1120983.KB894574_gene792 1.62e-06 52.4 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,1JN5A@119043|Rhodobiaceae 28211|Alphaproteobacteria P copper-translocating P-type ATPase actP - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS k141_9002_2 349521.HCH_03018 9.93e-83 266.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1XHHM@135619|Oceanospirillales 135619|Oceanospirillales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_16689_2 522373.Smlt2020 7.29e-59 187.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1X6GS@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 k141_2744_1 319224.Sputcn32_0564 1.08e-21 97.8 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,2Q9S7@267890|Shewanellaceae 1236|Gammaproteobacteria NU PFAM type II secretion system protein mshG - - ko:K02505,ko:K12278 - - - - ko00000,ko02044 - - - T2SSF k141_672_1 472759.Nhal_2432 9.27e-61 194.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales 135613|Chromatiales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_4039_1 1535422.ND16A_0329 1.35e-20 90.9 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,2Q6G6@267889|Colwelliaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_4039_2 1348114.OM33_02155 4.43e-38 140.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,2PZP9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - HlyD_D23,HlyD_D4 k141_21603_1 1121403.AUCV01000038_gene4226 1.03e-52 177.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria 1224|Proteobacteria C atp synthase - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_2037_1 1278309.KB907107_gene1748 2.98e-146 415.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1XJ32@135619|Oceanospirillales 135619|Oceanospirillales N Belongs to the flagella basal body rod proteins family flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_2037_2 1278309.KB907107_gene1747 2.15e-90 270.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1XI1V@135619|Oceanospirillales 135619|Oceanospirillales N Belongs to the flagella basal body rod proteins family flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_22268_1 714943.Mucpa_1441 9.04e-62 215.0 COG2911@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,4NHHA@976|Bacteroidetes,1J194@117747|Sphingobacteriia 976|Bacteroidetes MU C-terminal domain of CHU protein family - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3 k141_9661_1 498211.CJA_3586 8.84e-46 158.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1FGZ4@10|Cellvibrio 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_9003_1 105559.Nwat_2537 1.57e-08 55.1 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1WXRS@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_9003_2 713586.KB900536_gene1356 2.14e-07 52.4 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N k141_6235_1 1278309.KB907101_gene711 2.19e-225 639.0 COG3968@1|root,COG3968@2|Bacteria,1QDHB@1224|Proteobacteria,1RS3B@1236|Gammaproteobacteria,1XNV6@135619|Oceanospirillales 135619|Oceanospirillales S Glutamine synthetase type III N terminal - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C k141_7639_1 1123228.AUIH01000038_gene2752 1.03e-72 234.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XJ73@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_7639_2 1246459.KB898356_gene2236 7.12e-07 53.9 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,4B8MF@82115|Rhizobiaceae 28211|Alphaproteobacteria M transferase kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N k141_15221_1 584708.Apau_1498 5.57e-23 101.0 COG1352@1|root,COG1352@2|Bacteria,3TAGJ@508458|Synergistetes 508458|Synergistetes NT CheR methyltransferase, SAM binding domain - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_16691_1 323848.Nmul_A1668 6.32e-57 197.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,3743Q@32003|Nitrosomonadales 28216|Betaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_19482_1 555778.Hneap_0518 6.37e-18 90.1 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG3827@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3827@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_2745_2 83406.HDN1F_22340 5.29e-12 64.3 2DNT8@1|root,32Z10@2|Bacteria,1PVKP@1224|Proteobacteria,1RU3B@1236|Gammaproteobacteria,1JBC3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3135) - - - - - - - - - - - - DUF3135 k141_4040_2 388413.ALPR1_02540 1.55e-57 190.0 COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia 976|Bacteroidetes T PIN domain ybeZ_1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_11769_2 305900.GV64_01220 1.18e-22 90.1 2DRGE@1|root,33BM1@2|Bacteria,1R3NQ@1224|Proteobacteria,1T6A6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9004_1 765913.ThidrDRAFT_0236 1.63e-30 117.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1WY4W@135613|Chromatiales 135613|Chromatiales S PFAM Uncharacterised protein family (UPF0227) - - - ko:K07000 - - - - ko00000 - - - UPF0227 k141_6236_1 159087.Daro_3359 1.54e-24 99.4 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA k141_6236_2 997296.PB1_01335 2.2e-10 62.8 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_5574_1 935548.KI912159_gene2757 4.11e-68 230.0 COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TV0G@28211|Alphaproteobacteria,43RVC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_7 k141_5574_2 1173264.KI913949_gene1061 1.41e-43 144.0 COG0346@1|root,COG0346@2|Bacteria,1G504@1117|Cyanobacteria,1HAPB@1150|Oscillatoriales 1117|Cyanobacteria E Lactoylglutathione lyase gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_17379_1 1049564.TevJSym_an00070 1.15e-211 607.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1J4ZY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional accessory protein yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_14540_1 1278309.KB907106_gene1226 1.86e-66 218.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales 135619|Oceanospirillales M gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_14540_2 1278309.KB907106_gene1227 4.29e-130 381.0 COG1639@1|root,COG1639@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,1XI83@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein - - - - - - - - - - - - HDOD k141_9662_1 1288826.MSNKSG1_14997 7.47e-167 491.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,46421@72275|Alteromonadaceae 1236|Gammaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_2038_1 1288826.MSNKSG1_12517 7.91e-177 494.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,464E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0422 IGPS k141_673_1 1122194.AUHU01000006_gene524 3.84e-203 602.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_9005_1 1122599.AUGR01000009_gene2426 7.29e-152 468.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_19483_1 105559.Nwat_3050 3.13e-142 428.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1WXCY@135613|Chromatiales 135613|Chromatiales G phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_2746_1 1218076.BAYB01000002_gene105 2.18e-45 160.0 COG2084@1|root,COG2084@2|Bacteria,1RC5B@1224|Proteobacteria,2WDQV@28216|Betaproteobacteria,1KATU@119060|Burkholderiaceae 28216|Betaproteobacteria I NAD binding domain of 6-phosphogluconate dehydrogenase - - - - - - - - - - - - NAD_binding_2 k141_11770_1 1121440.AUMA01000003_gene2970 3.32e-08 62.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2M7ZM@213115|Desulfovibrionales 28221|Deltaproteobacteria M TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_7640_1 323848.Nmul_A2334 6.65e-121 371.0 COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,371M3@32003|Nitrosomonadales 28216|Betaproteobacteria E extracellular solute-binding protein, family 5 oppA - - - - - - - - - - - SBP_bac_5 k141_7640_2 545264.KB898753_gene1780 6.06e-68 213.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1WX1J@135613|Chromatiales 135613|Chromatiales I Enoyl- acyl-carrier-protein reductase NADH - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_22273_1 62928.azo2556 9.18e-23 103.0 COG0689@1|root,COG2304@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG0689@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QU09@1224|Proteobacteria 1224|Proteobacteria M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - Calx-beta,DUF4347,He_PIG,VWA_2 k141_2039_2 1244869.H261_06489 1.03e-21 91.7 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,2JUV5@204441|Rhodospirillales 204441|Rhodospirillales S Aldo/keto reductase family - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red k141_16694_1 388467.A19Y_1273 7.94e-36 141.0 COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k141_20062_1 1288826.MSNKSG1_00211 0.0 1156.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,4651D@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 DXP_synthase_N,Transket_pyr,Transketolase_C k141_20062_2 1288826.MSNKSG1_00206 1.72e-146 412.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,465AE@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_437,iPC815.YPO2222,iSbBS512_1146.SbBS512_E1505,iUTI89_1310.UTI89_C1548 GTP_cyclohydro2 k141_20062_3 1288826.MSNKSG1_00201 1.82e-106 307.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,4677K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoaC k141_20062_4 1288826.MSNKSG1_00196 3.86e-214 593.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,467U6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the Nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_20062_5 1288826.MSNKSG1_00191 3.98e-276 757.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,464AB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_20062_6 1288826.MSNKSG1_00186 0.0 1116.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_9006_1 1288826.MSNKSG1_02599 2.14e-183 533.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,465DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_7641_1 768671.ThimaDRAFT_1588 1.88e-66 211.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales 135613|Chromatiales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_15223_1 357804.Ping_3709 7.23e-131 384.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,2QJ8J@267894|Psychromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_15223_2 357804.Ping_3710 5.14e-64 202.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,2QJ1Q@267894|Psychromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 - - ABC_tran k141_14543_1 443152.MDG893_18557 6.24e-11 65.5 COG5662@1|root,COG5662@2|Bacteria,1NGBV@1224|Proteobacteria,1SGXN@1236|Gammaproteobacteria,46BR4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 k141_22276_1 313596.RB2501_03425 7.95e-06 53.1 COG1361@1|root,COG2730@1|root,COG2885@1|root,COG3209@1|root,COG1361@2|Bacteria,COG2730@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,4NG16@976|Bacteroidetes,1HY10@117743|Flavobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,SdrD_B k141_17380_1 1232410.KI421425_gene1550 1.02e-58 204.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_17380_2 1232410.KI421425_gene1549 3.57e-58 207.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,43CT2@68525|delta/epsilon subdivisions,2X80K@28221|Deltaproteobacteria,43TUA@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_2041_1 323261.Noc_2813 4.13e-61 199.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales 135613|Chromatiales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_14544_1 1406840.Q763_05860 1.38e-39 150.0 COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia,2NU9W@237|Flavobacterium 976|Bacteroidetes S membrane - - - - - - - - - - - - YfhO k141_15239_1 1120977.JHUX01000008_gene436 9.38e-18 89.7 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,3NKUQ@468|Moraxellaceae 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_15239_2 472759.Nhal_2677 1.21e-177 509.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales 135613|Chromatiales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_9044_2 1236973.JCM9157_2179 5.6e-67 228.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS k141_16716_1 713586.KB900536_gene2898 4.53e-66 213.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_19513_1 1288826.MSNKSG1_10218 3.49e-115 336.0 COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1RNJM@1236|Gammaproteobacteria,469UB@72275|Alteromonadaceae 1236|Gammaproteobacteria K AraC-like ligand binding domain hpaA - - ko:K02508 - - - - ko00000,ko03000 - - - AraC_binding,Cupin_2,HTH_18 k141_9045_1 367336.OM2255_09676 3.05e-58 181.0 COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hemimethylated DNA binding hspQ - - ko:K11940 - - - - ko00000,ko03036 - - - YccV-like k141_9045_2 1417296.U879_00950 3.1e-20 89.7 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria 28211|Alphaproteobacteria E gamma-glutamyltransferase ywrD - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_17416_1 580332.Slit_1715 3.94e-186 531.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,44WIW@713636|Nitrosomonadales 28216|Betaproteobacteria C Fumarate reductase flavoprotein C-term - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_2781_1 757424.Hsero_0862 5.32e-17 86.3 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,473UA@75682|Oxalobacteraceae 28216|Betaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_14577_1 1163617.SCD_n02338 2.72e-67 221.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,2VPN4@28216|Betaproteobacteria 28216|Betaproteobacteria V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_14577_3 314345.SPV1_09739 3.18e-14 68.9 COG3258@1|root,COG3258@2|Bacteria 2|Bacteria C Cytochrome c - - 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C k141_6838_1 1278309.KB907100_gene1899 9.09e-248 707.0 COG1502@1|root,COG1502@2|Bacteria,1R5BX@1224|Proteobacteria 1224|Proteobacteria I phospholipase d transphosphatidylase - - - - - - - - - - - - PLDc_2 k141_769_1 998674.ATTE01000001_gene1809 1.53e-79 254.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales 1236|Gammaproteobacteria E TIGRFAM Acetolactate synthase, large subunit, biosynthetic ilvB GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_4155 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_6337_1 189425.PGRAT_12535 2.15e-41 140.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,26XFZ@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator ydeP3 - - - - - - - - - - - HxlR k141_18895_1 761193.Runsl_5034 1.59e-76 241.0 COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia 976|Bacteroidetes G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_13336_1 243233.MCA1475 6.63e-78 253.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales 135618|Methylococcales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_14026_1 745014.OMB55_00022620 3.28e-32 123.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 ATP-synt_ab,ATP-synt_ab_N k141_14026_2 713586.KB900536_gene2124 1.24e-134 389.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_14026_3 572477.Alvin_0044 2.18e-18 84.3 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1WVYR@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_11267_1 485918.Cpin_4000 2.12e-24 107.0 COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1IPDU@117747|Sphingobacteriia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core k141_2856_1 1249627.D779_0297 3.38e-83 264.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_21032_1 1288826.MSNKSG1_10888 1.83e-110 318.0 COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,1RPY6@1236|Gammaproteobacteria,4667J@72275|Alteromonadaceae 1236|Gammaproteobacteria D Di-iron-containing protein involved in the repair of iron-sulfur clusters ytfE GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564 - ko:K07322 - - - - ko00000 - - iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820 Hemerythrin,ScdA_N k141_21032_2 1288826.MSNKSG1_10893 9.22e-196 561.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,464BD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3256 Nitric oxide reductase large subunit norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k141_8431_1 1288826.MSNKSG1_01533 7.36e-128 376.0 COG1653@1|root,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,1RSBF@1236|Gammaproteobacteria,46D56@72275|Alteromonadaceae 1236|Gammaproteobacteria G Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_8431_2 1288826.MSNKSG1_01538 5.59e-232 646.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,46AQD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 k141_16097_1 1206731.BAGB01000064_gene7349 7.55e-10 61.6 COG1309@1|root,COG1309@2|Bacteria,2IFAN@201174|Actinobacteria,4G0SB@85025|Nocardiaceae 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_16097_2 1158146.KB907121_gene1133 2.84e-17 79.7 2ECQ3@1|root,336MT@2|Bacteria,1NB5U@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_16097_3 2340.JV46_16620 4.98e-37 139.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SBMS@1236|Gammaproteobacteria,1JBHM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin k141_18896_1 391626.OAN307_c36390 1.64e-105 311.0 COG1028@1|root,COG1028@2|Bacteria,1MXE0@1224|Proteobacteria,2U1P2@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Dehydrogenase - - - - - - - - - - - - adh_short_C2 k141_21658_1 1121921.KB898708_gene1328 8.36e-15 72.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,2PMVR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria O ABC transporter sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - ko:K09013 - - - - ko00000,ko02000 - - iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 ABC_tran k141_21658_2 860228.Ccan_02850 7.56e-13 74.3 COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia,1EQSQ@1016|Capnocytophaga 976|Bacteroidetes O FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 k141_3563_1 123899.JPQP01000017_gene2423 8.27e-23 96.7 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,3T1F5@506|Alcaligenaceae 28216|Betaproteobacteria N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_3563_2 1286106.MPL1_12758 1.03e-29 108.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,4617Z@72273|Thiotrichales 72273|Thiotrichales N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_4244_2 1000565.METUNv1_02453 3.33e-22 95.1 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA k141_16806_1 1121937.AUHJ01000013_gene822 1.23e-23 99.4 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_16806_2 396595.TK90_2485 2.38e-29 106.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales 135613|Chromatiales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic k141_17473_2 246200.SPO0857 1.94e-15 77.8 COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,4NC1D@97050|Ruegeria 28211|Alphaproteobacteria G Aldose 1-epimerase galM GO:0003674,GO:0003824,GO:0004034,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k141_15434_1 318161.Sden_0133 2.11e-26 112.0 COG3209@1|root,COG3209@2|Bacteria,1NG5W@1224|Proteobacteria,1SYZM@1236|Gammaproteobacteria,2QBGD@267890|Shewanellaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - k141_11937_1 443152.MDG893_06179 1.31e-07 61.2 COG2340@1|root,COG3209@1|root,COG2340@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - Big_3_5,CAP,SLH k141_11937_2 1123073.KB899244_gene186 1.35e-10 69.7 COG1470@1|root,COG3209@1|root,COG5184@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,1N55D@1224|Proteobacteria,1T481@1236|Gammaproteobacteria,1XD8U@135614|Xanthomonadales 135614|Xanthomonadales DMZ IPT/TIG domain - - - - - - - - - - - - TIG k141_21659_1 948106.AWZT01000049_gene499 1.92e-92 281.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,1JZSI@119060|Burkholderiaceae 28216|Betaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_13337_1 1278309.KB907099_gene2844 1.34e-159 453.0 COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M PFAM porin Gram-negative type - - - - - - - - - - - - Porin_4 k141_13337_2 1278309.KB907099_gene2845 7.11e-32 118.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XJNB@135619|Oceanospirillales 135619|Oceanospirillales M (Lipo)protein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_15435_1 1026882.MAMP_01616 2.15e-29 110.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,460FX@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_15435_2 56110.Oscil6304_1013 2.56e-13 69.7 COG0668@1|root,COG0668@2|Bacteria 2|Bacteria M transmembrane transport - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel k141_20311_1 1278309.KB907100_gene1942 1.12e-33 118.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1XKXP@135619|Oceanospirillales 135619|Oceanospirillales I Cyclase dehydrase - - - - - - - - - - - - Polyketide_cyc k141_21666_1 1249627.D779_0176 4.02e-07 51.2 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_9831_1 1278309.KB907102_gene228 5.82e-62 212.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XHPB@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_11947_1 1288826.MSNKSG1_14697 3.45e-157 475.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,464X6@72275|Alteromonadaceae 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_5691_1 870187.Thini_2710 4.26e-77 237.0 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Isochorismatase hydrolase - - - - - - - - - - - - Isochorismatase k141_4941_1 471854.Dfer_3377 1.21e-15 77.4 COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia 976|Bacteroidetes L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_4941_2 926562.Oweho_2299 5.16e-25 98.6 29VE2@1|root,30GUS@2|Bacteria,4NP29@976|Bacteroidetes,1I29M@117743|Flavobacteriia,2PBUQ@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k141_13351_1 536019.Mesop_3316 2.8e-40 144.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,43J4M@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_9143_1 90814.KL370891_gene1132 3.49e-66 208.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales 72273|Thiotrichales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_9143_2 1122194.AUHU01000002_gene2442 1.73e-59 199.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,4646Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3323,iPC815.YPO3377 CTP_synth_N,GATase k141_15446_1 765912.Thimo_0132 1.15e-17 78.6 COG3118@1|root,COG3118@2|Bacteria,1RI6E@1224|Proteobacteria,1S8B4@1236|Gammaproteobacteria,1WYJW@135613|Chromatiales 135613|Chromatiales O Belongs to the thioredoxin family - - - ko:K05838 - - - - ko00000,ko03110 - - - Thioredoxin k141_15446_2 1049564.TevJSym_aa01710 2.93e-45 147.0 2CDMX@1|root,32S1K@2|Bacteria,1N1I8@1224|Proteobacteria,1S9N4@1236|Gammaproteobacteria,1JB6N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15446_3 1163617.SCD_n02060 4.51e-29 119.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria 1224|Proteobacteria C oxidoreductase FAD NAD(P)-binding domain protein - - - - - - - - - - - - FAD_binding_6,Fer2 k141_1472_2 882378.RBRH_02298 4.32e-80 247.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,1JZUI@119060|Burkholderiaceae 28216|Betaproteobacteria V ABC transporter ybhF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_7778_1 338966.Ppro_3157 3.31e-05 47.8 COG0226@1|root,COG0226@2|Bacteria,1PVGI@1224|Proteobacteria,43A46@68525|delta/epsilon subdivisions,2X1XS@28221|Deltaproteobacteria,43VRM@69541|Desulfuromonadales 28221|Deltaproteobacteria P PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - - k141_7778_2 1158760.AQXP01000055_gene1298 2.66e-05 46.2 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_7051_1 380394.Lferr_1061 1.65e-26 110.0 COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,1RNFZ@1236|Gammaproteobacteria,2NCJ0@225057|Acidithiobacillales 225057|Acidithiobacillales G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_7051_2 1266925.JHVX01000005_gene1848 2.05e-05 46.2 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_778_1 396588.Tgr7_0184 1.39e-46 160.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_778_2 740709.A10D4_08919 2.26e-42 153.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,2QFHK@267893|Idiomarinaceae 1236|Gammaproteobacteria E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_19594_1 472759.Nhal_3933 5.36e-25 105.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1X0CU@135613|Chromatiales 135613|Chromatiales H HemY domain protein - - - ko:K02498 - - - - ko00000 - - - HemY_N k141_20328_1 472759.Nhal_2578 4.36e-160 487.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales 135613|Chromatiales Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_5692_1 465817.ETA_11140 3.35e-29 117.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,3X4UC@551|Erwinia 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iNRG857_1313.NRG857_12000 Glucokinase k141_21050_1 1049564.TevJSym_ab02100 2.97e-125 370.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1J4CY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_6348_2 631362.Thi970DRAFT_00019 2.54e-42 143.0 2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,1S9KI@1236|Gammaproteobacteria,1X104@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_18906_1 1122194.AUHU01000021_gene3469 5.55e-26 100.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,467U5@72275|Alteromonadaceae 1236|Gammaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k141_18906_2 765912.Thimo_2872 1.25e-99 291.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1WWG3@135613|Chromatiales 135613|Chromatiales K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k141_3576_1 574966.KB898648_gene969 3.57e-105 324.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XIWM@135619|Oceanospirillales 135619|Oceanospirillales L DNA helicase recQ1 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_21667_1 857087.Metme_1515 8.93e-71 231.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1XE57@135618|Methylococcales 135618|Methylococcales G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_12634_2 396588.Tgr7_0491 5.55e-51 167.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity yafP - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 k141_12634_3 574966.KB898649_gene139 2.01e-45 150.0 COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1XKKQ@135619|Oceanospirillales 135619|Oceanospirillales O Glutaredoxin - - - - - - - - - - - - GST_N_3,Glutaredoxin k141_12634_4 626887.J057_16845 2.33e-05 45.8 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria,4665I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_14039_1 196367.JNFG01000199_gene3251 2.31e-63 202.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJU2@28216|Betaproteobacteria,1KGZF@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the arginase family rocF - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_5693_1 243233.MCA2967 5.12e-50 171.0 COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1XECH@135618|Methylococcales 135618|Methylococcales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_18212_1 247633.GP2143_15881 3.02e-132 398.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1J5CT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase/oxoprolinase hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_4254_1 1001585.MDS_1958 1.82e-46 166.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1YD43@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k141_4254_2 765913.ThidrDRAFT_0047 2.85e-69 219.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,1WW2D@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH k141_7779_1 985054.JQEZ01000002_gene3180 1.25e-18 90.9 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,4NA0E@97050|Ruegeria 28211|Alphaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_13352_1 1305735.JAFT01000005_gene2560 5.13e-06 52.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2PFG9@252301|Oceanicola 28211|Alphaproteobacteria H TonB dependent receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_7052_1 90814.KL370891_gene1925 1.16e-44 160.0 COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,LGT k141_779_1 477184.KYC_08040 9.37e-54 187.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria 28216|Betaproteobacteria H PFAM UbiA prenyltransferase - - - - - - - - - - - - HAD,UbiA k141_21051_1 391589.RGAI101_3868 2.18e-15 76.6 2CA6E@1|root,32ZKX@2|Bacteria,1NDUX@1224|Proteobacteria,2UIDZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_66_1 1122236.KB905141_gene1345 3.34e-67 208.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,2KMQ4@206350|Nitrosomonadales 206350|Nitrosomonadales S PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD k141_66_2 1123399.AQVE01000015_gene1806 5.19e-115 343.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,45ZWB@72273|Thiotrichales 72273|Thiotrichales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_12635_1 565045.NOR51B_478 1.85e-69 223.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1J5CE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_15449_1 1288826.MSNKSG1_01503 4.03e-138 398.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,464P2@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases HA62_10695 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_17483_1 1163617.SCD_n01648 7.44e-13 73.2 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria 28216|Betaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_17483_2 765914.ThisiDRAFT_2568 1.88e-36 130.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1WYGU@135613|Chromatiales 135613|Chromatiales N flagellar protein FliS - - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_18907_1 985255.APHJ01000038_gene2841 8.64e-37 125.0 COG4115@1|root,COG4115@2|Bacteria,4NSJD@976|Bacteroidetes,1IHPM@117743|Flavobacteriia,2P7P6@244698|Gillisia 976|Bacteroidetes S YoeB-like toxin of bacterial type II toxin-antitoxin system - - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin k141_19018_2 596153.Alide_2766 5.28e-76 234.0 COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria,4ADJ0@80864|Comamonadaceae 28216|Betaproteobacteria Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_19018_3 713586.KB900536_gene2264 2.31e-58 191.0 COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_2984_1 67593.Physo109305 2e-30 125.0 2CDQ5@1|root,2S3EW@2759|Eukaryota,3QGSN@4776|Peronosporales 4776|Peronosporales S DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 k141_14848_1 1278309.KB907101_gene776 6.47e-170 479.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1XII5@135619|Oceanospirillales 135619|Oceanospirillales I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_14848_2 1278309.KB907101_gene775 1.58e-198 555.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1XIK4@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_14848_3 1122201.AUAZ01000017_gene2905 4.59e-27 99.4 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,468BN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p k141_14848_4 1278309.KB907101_gene773 1.29e-63 198.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XJKJ@135619|Oceanospirillales 135619|Oceanospirillales S metal-binding, possibly nucleic acid-binding protein - - - ko:K07040 - - - - ko00000 - - - DUF177 k141_12037_1 420324.KI912045_gene4601 1.95e-65 206.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2U5HG@28211|Alphaproteobacteria,1JRYT@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_4392_1 1519464.HY22_04890 5.89e-13 73.9 COG1629@1|root,COG4771@2|Bacteria,1FEFM@1090|Chlorobi 1090|Chlorobi P CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_21797_1 722419.PH505_bp00120 6.37e-100 296.0 COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,2Q1RV@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O peroxiredoxin glutaredoxin VY92_02980 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Glutaredoxin,Redoxin k141_10679_1 1165096.ARWF01000001_gene2027 2.17e-110 327.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KKH8@206350|Nitrosomonadales 206350|Nitrosomonadales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_3692_2 1121878.AUGL01000008_gene1395 3.8e-37 135.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_892_1 1122201.AUAZ01000003_gene2100 6.58e-64 219.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k141_19041_1 314264.ROS217_09445 1.19e-68 216.0 COG1802@1|root,COG1802@2|Bacteria,1R4P5@1224|Proteobacteria,2U6CA@28211|Alphaproteobacteria,46PI4@74030|Roseovarius 28211|Alphaproteobacteria K Transcriptional regulator, GntR family - - - - - - - - - - - - FCD,GntR k141_5054_2 1218076.BAYB01000022_gene3854 1.47e-33 128.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria,1K0JH@119060|Burkholderiaceae 28216|Betaproteobacteria T response regulator - - - - - - - - - - - - LytTR,Response_reg k141_5054_3 1046724.KB889828_gene2916 4.92e-14 73.2 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,4666A@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_17630_1 1415780.JPOG01000001_gene1422 6.49e-24 100.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,1X5RF@135614|Xanthomonadales 135614|Xanthomonadales M Chitin synthase - - - - - - - - - - - - Glyco_tranf_2_3 k141_16924_1 1116375.VEJY3_10455 3.12e-21 92.4 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1SXJJ@1236|Gammaproteobacteria,1XZR7@135623|Vibrionales 135623|Vibrionales E Transglutaminase/protease-like homologues - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_16924_2 1232683.ADIMK_4140 0.0 946.0 COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,1RPDC@1236|Gammaproteobacteria,465B2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - Alpha-E,CP_ATPgrasp_2 k141_16924_3 1116375.VEJY3_10445 1.79e-69 234.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1Y0NC@135623|Vibrionales 135623|Vibrionales E Putative amidoligase enzyme (DUF2126) - - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core k141_4393_1 1220582.RRU01S_26_00410 1.36e-15 75.9 COG3535@1|root,COG3535@2|Bacteria,1NCBV@1224|Proteobacteria,2TU70@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF917) - - - ko:K09703 - - - - ko00000 - - - DUF917 k141_4393_2 391616.OA238_c15590 9.23e-21 91.3 COG1653@1|root,COG1846@1|root,COG1653@2|Bacteria,COG1846@2|Bacteria,1N1NW@1224|Proteobacteria,2VFGD@28211|Alphaproteobacteria 28211|Alphaproteobacteria GK Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - HTH_IclR,SBP_bac_8 k141_9921_1 998674.ATTE01000001_gene508 1.83e-121 365.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_20448_2 187272.Mlg_1032 2.33e-52 168.0 COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1X11H@135613|Chromatiales 135613|Chromatiales O Glutathione S-transferase, N-terminal domain - - - - - - - - - - - - GST_N_3 k141_1591_1 1049564.TevJSym_ad00720 3.05e-96 293.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1J5B5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0382 AIRS,AIRS_C k141_12763_1 314278.NB231_15213 1.77e-143 422.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_12763_2 314278.NB231_15218 5.2e-10 59.3 2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,1S67B@1236|Gammaproteobacteria,1X0TY@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_5822_1 1123237.Salmuc_02522 8.46e-103 308.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 k141_7878_1 1288826.MSNKSG1_14152 9.05e-178 504.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,467J0@72275|Alteromonadaceae 1236|Gammaproteobacteria G Sucrose phosphorylase - GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_7878_2 1288826.MSNKSG1_14147 3.77e-147 434.0 COG0380@1|root,COG0561@1|root,COG0380@2|Bacteria,COG0561@2|Bacteria,1MUIY@1224|Proteobacteria,1RNG7@1236|Gammaproteobacteria,469G3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyltransferase family 20 ggpS - 2.4.1.213 ko:K03692 - - - - ko00000,ko01000 - GT20 - Glyco_transf_20,S6PP k141_9922_1 391937.NA2_19453 3.25e-52 173.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,2U92R@28211|Alphaproteobacteria,43P1H@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_19043_1 1278309.KB907100_gene1815 3.59e-83 266.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XHV8@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_20449_1 349102.Rsph17025_0933 1.94e-92 300.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,1FAN1@1060|Rhodobacter 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC k141_12061_1 314278.NB231_15233 1.39e-81 245.0 COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,1RXZV@1236|Gammaproteobacteria,1WWCC@135613|Chromatiales 135613|Chromatiales CQ BMC - - - - - - - - - - - - BMC k141_15568_1 225937.HP15_1349 4.43e-71 225.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,4680U@72275|Alteromonadaceae 1236|Gammaproteobacteria M Secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_13455_1 1085623.GNIT_0117 4.06e-88 271.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,469IV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_11388_1 1111732.AZOD01000056_gene1270 5.94e-11 57.4 2EG3W@1|root,339VW@2|Bacteria,1NHIR@1224|Proteobacteria,1SGXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4395_1 314345.SPV1_00095 2.7e-45 167.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_5823_1 1244869.H261_01696 7.1e-21 94.7 COG0845@1|root,COG0845@2|Bacteria,1R3U4@1224|Proteobacteria,2TW9A@28211|Alphaproteobacteria,2JSE7@204441|Rhodospirillales 204441|Rhodospirillales M Biotin-lipoyl like - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_18316_1 1278309.KB907101_gene568 2e-124 359.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XHB5@135619|Oceanospirillales 135619|Oceanospirillales H UBA THIF-type NAD FAD binding - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF k141_18316_2 1278309.KB907101_gene569 2.43e-227 636.0 COG2199@1|root,COG3706@2|Bacteria,1QUXS@1224|Proteobacteria,1T35R@1236|Gammaproteobacteria,1XRTA@135619|Oceanospirillales 135619|Oceanospirillales T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GGDEF,PAS_3 k141_18316_3 1278309.KB907101_gene570 0.0 900.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XHI9@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_18316_4 1278309.KB907101_gene571 4.79e-64 198.0 COG3308@1|root,COG3308@2|Bacteria,1N6Y3@1224|Proteobacteria,1SFFS@1236|Gammaproteobacteria,1XRG7@135619|Oceanospirillales 135619|Oceanospirillales S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_18316_5 999141.GME_15885 4.43e-53 172.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1XHQP@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_5055_1 1172190.M947_05130 0.000146 52.4 COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,42TK1@68525|delta/epsilon subdivisions,2YS54@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S KAP family P-loop domain - - - - - - - - - - - - KAP_NTPase k141_19044_1 1168067.JAGP01000001_gene1351 8.54e-75 237.0 COG1462@1|root,COG1462@2|Bacteria,1RIEQ@1224|Proteobacteria,1RURU@1236|Gammaproteobacteria,462A7@72273|Thiotrichales 72273|Thiotrichales M curli production assembly transport component CsgG - - - - - - - - - - - - - k141_3693_1 870187.Thini_4285 1.18e-10 59.7 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_3693_2 1123401.JHYQ01000002_gene2785 4.03e-42 150.0 COG0547@1|root,COG0547@2|Bacteria,1PI4H@1224|Proteobacteria,1T9UI@1236|Gammaproteobacteria,4623U@72273|Thiotrichales 72273|Thiotrichales E PFAM Glycosyl transferase family, a b domain - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_21167_2 1453501.JELR01000002_gene1165 1.75e-117 358.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4655N@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_1592_1 391615.ABSJ01000050_gene1157 3.36e-120 371.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1J4TP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_16220_1 1042375.AFPL01000055_gene2278 1.38e-07 52.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,466WT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_16220_2 1278309.KB907099_gene2843 2.86e-77 258.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XHUD@135619|Oceanospirillales 135619|Oceanospirillales L Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_10680_1 1127673.GLIP_1517 6.09e-169 484.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_16925_1 83219.PM02_04600 4.09e-111 332.0 COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,2TVVP@28211|Alphaproteobacteria,3ZVCS@60136|Sulfitobacter 28211|Alphaproteobacteria E Creatinase/Prolidase N-terminal domain - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_16925_2 411684.HPDFL43_12211 1.54e-23 99.0 COG1171@1|root,COG1171@2|Bacteria,1QVNS@1224|Proteobacteria,2TUHW@28211|Alphaproteobacteria,43IVS@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Diaminopropionate ammonia-lyase dpaL GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15 ko:K01751 - - - - ko00000,ko01000 - - - PALP k141_5824_1 754477.Q7C_1859 1.91e-08 58.2 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,4619A@72273|Thiotrichales 72273|Thiotrichales H PFAM Uroporphyrinogen-III synthase HemD - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 k141_14145_1 1121015.N789_12570 5.88e-50 170.0 COG1108@1|root,COG1108@2|Bacteria,1QJJ7@1224|Proteobacteria,1S3BV@1236|Gammaproteobacteria 1236|Gammaproteobacteria P PFAM ABC-3 protein - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 k141_14145_2 1517681.HW45_04095 5.31e-44 152.0 COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1S41U@1236|Gammaproteobacteria,1XWWX@135623|Vibrionales 135623|Vibrionales S Las17-binding protein actin regulator CT2216 - - - - - - - - - - - Ysc84 k141_14145_3 1163617.SCD_n00731 2.39e-89 276.0 COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,2WGRP@28216|Betaproteobacteria 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - Peptidase_C39_2,TPR_16 k141_14145_4 1168067.JAGP01000001_gene229 8.52e-14 68.6 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,462W0@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_13456_1 580332.Slit_1716 9.11e-66 201.0 2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,2W3NZ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_12765_1 1249627.D779_0468 2.89e-130 403.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_15569_1 926550.CLDAP_01010 3.71e-30 128.0 COG0784@1|root,COG2202@1|root,COG3290@1|root,COG3614@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3614@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - - - - - - - - - - CHASE,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_20450_1 1122201.AUAZ01000001_gene2230 2.76e-111 338.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,465X3@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1030 Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_3694_1 1079460.ATTQ01000009_gene563 1.4e-34 131.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2TTZ2@28211|Alphaproteobacteria,4B98P@82115|Rhizobiaceae 28211|Alphaproteobacteria HP ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_1593_1 1209072.ALBT01000032_gene1908 1.3e-75 234.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1FG01@10|Cellvibrio 1236|Gammaproteobacteria J Prokaryotic glutathione synthetase, ATP-grasp domain rimK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_21168_2 1453501.JELR01000001_gene1901 0.000337 44.7 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_8574_1 1049564.TevJSym_av00360 6.16e-134 407.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU general secretion pathway protein D xcsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_3001_1 236097.ADG881_3029 0.000434 52.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XHFM@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 k141_893_1 497321.C664_08223 1.04e-20 90.1 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,2KUGK@206389|Rhodocyclales 206389|Rhodocyclales L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18 k141_893_2 1278309.KB907100_gene2071 9.29e-111 325.0 COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,1QUHI@1224|Proteobacteria,1S3BZ@1236|Gammaproteobacteria,1XJ8B@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_893_3 1278309.KB907100_gene2072 8.52e-184 514.0 COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,1RMXB@1236|Gammaproteobacteria,1XHU0@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_4396_1 349521.HCH_00578 5.69e-58 193.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XJA6@135619|Oceanospirillales 135619|Oceanospirillales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_21799_1 1288826.MSNKSG1_06558 8.99e-56 183.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,466N2@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily hcaT - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_21799_2 1288826.MSNKSG1_06553 8.69e-243 671.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,465YY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II/IV secretion system protein - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_21799_3 1288826.MSNKSG1_06548 6.14e-182 509.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,4651F@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k141_2259_1 1288826.MSNKSG1_01178 3.71e-115 343.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46456@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_2259_2 1288826.MSNKSG1_01183 2.2e-49 157.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,467U2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_2259_3 1288826.MSNKSG1_01188 3.57e-123 351.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_2259_4 1288826.MSNKSG1_01193 7.45e-177 493.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,464K1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT k141_2259_5 1288826.MSNKSG1_01198 2.22e-76 228.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,466X0@72275|Alteromonadaceae 1236|Gammaproteobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_2259_6 1288826.MSNKSG1_01203 5.74e-212 586.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG4974 Site-specific recombinase XerD xerD GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_2259_7 1288826.MSNKSG1_01208 4.83e-173 483.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,466TU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 k141_2259_8 1288826.MSNKSG1_01213 7.86e-299 819.0 COG0317@1|root,COG0460@1|root,COG0317@2|Bacteria,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,463Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_2259_9 1288826.MSNKSG1_01218 8.23e-94 285.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,463ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine synthase thrC GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025 PALP,Thr_synth_N k141_19188_1 314256.OG2516_14683 1.79e-33 132.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2PC8C@252301|Oceanicola 28211|Alphaproteobacteria S TamB, inner membrane protein subunit of TAM complex tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_19821_2 314278.NB231_01409 2.09e-52 171.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales 135613|Chromatiales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_6557_2 1121356.AQUW01000002_gene1654 4.97e-14 69.7 COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,22NJU@1653|Corynebacteriaceae 201174|Actinobacteria P Rieske-like [2Fe-2S] domain hcaC - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske k141_8690_1 1123326.JFBL01000006_gene1000 5.46e-13 70.5 COG0834@1|root,COG0834@2|Bacteria,1N0VS@1224|Proteobacteria,42WD3@68525|delta/epsilon subdivisions,2YSMV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria ET Bacterial extracellular solute-binding proteins, family 3 - - - - - - - - - - - - SBP_bac_3 k141_8690_2 443598.AUFA01000026_gene1763 1.46e-09 62.8 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JWM7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Periplasmic sensor domain found in signal transduction proteins - - - - - - - - - - - - CHASE5,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_334_1 349521.HCH_00962 2.36e-59 197.0 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XHE6@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,CbiA,GATase_3 k141_1022_1 519989.ECTPHS_06197 4.06e-08 56.6 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,1X2J4@135613|Chromatiales 135613|Chromatiales T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_7304_1 105559.Nwat_1588 8.54e-20 90.5 COG0477@1|root,COG0477@2|Bacteria,1QTUM@1224|Proteobacteria,1T1HT@1236|Gammaproteobacteria,1WW5Z@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_7304_2 1349767.GJA_2694 1.25e-71 242.0 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,475S0@75682|Oxalobacteraceae 28216|Betaproteobacteria T Double sensory domain of two-component sensor kinase - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_3 k141_15663_1 1278309.KB907099_gene2657 7.23e-31 114.0 COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,1RRB8@1236|Gammaproteobacteria,1XKVJ@135619|Oceanospirillales 135619|Oceanospirillales S MOSC domain - - - - - - - - - - - - MOSC k141_15663_2 1278309.KB907099_gene2658 8.05e-100 293.0 COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,1XJ82@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0502 family - - - ko:K09915 - - - - ko00000 - - - DUF480 k141_4538_1 1336235.JAEG01000004_gene3972 1.26e-27 111.0 COG2197@1|root,COG2197@2|Bacteria,1PGNQ@1224|Proteobacteria,2VB52@28211|Alphaproteobacteria,4BCYN@82115|Rhizobiaceae 28211|Alphaproteobacteria K AroM protein - - - - - - - - - - - - AroM,GerE k141_11493_1 1046724.KB889869_gene2525 2.4e-78 249.0 COG4983@1|root,COG4983@2|Bacteria,1N636@1224|Proteobacteria,1RZVN@1236|Gammaproteobacteria,46ACV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k141_14959_1 1341151.ASZU01000003_gene2438 4.72e-46 161.0 COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,4IF4B@91061|Bacilli,27CH3@186824|Thermoactinomycetaceae 91061|Bacilli S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF k141_3808_1 1278309.KB907104_gene942 6.01e-132 379.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,1XHST@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_3808_2 267608.RSc0497 1.44e-16 75.5 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,1K3IP@119060|Burkholderiaceae 28216|Betaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_6558_1 314278.NB231_15203 1.41e-35 126.0 COG2193@1|root,COG2193@2|Bacteria,1PE4V@1224|Proteobacteria,1SAG5@1236|Gammaproteobacteria,1WZ24@135613|Chromatiales 135613|Chromatiales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_6558_2 1255043.TVNIR_2981 6.09e-27 100.0 COG2154@1|root,COG2154@2|Bacteria,1N7XJ@1224|Proteobacteria,1T12K@1236|Gammaproteobacteria,1X2MX@135613|Chromatiales 135613|Chromatiales H Pterin 4 alpha carbinolamine dehydratase - - - - - - - - - - - - Pterin_4a k141_16320_1 1278309.KB907102_gene86 1.46e-133 386.0 COG3725@1|root,COG3725@2|Bacteria 2|Bacteria - - ampE GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 6.3.1.10 ko:K02227,ko:K03807 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - AmpE,CobD_Cbib k141_16320_2 1278309.KB907102_gene85 5.88e-82 247.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XJIY@135619|Oceanospirillales 135619|Oceanospirillales V Negative regulator of beta-lactamase expression ampD - 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 k141_16320_3 1278309.KB907102_gene84 4.27e-172 483.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1XHMZ@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_20589_1 987059.RBXJA2T_15678 7.69e-34 123.0 COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria 28216|Betaproteobacteria S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF559 k141_21956_1 1278309.KB907100_gene1928 6.11e-114 328.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1XJQ3@135619|Oceanospirillales 135619|Oceanospirillales F ADP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX,Nudix_N_2 k141_21956_2 94122.Shewana3_0285 6.41e-20 80.9 COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae 1236|Gammaproteobacteria S Proteolipid membrane potential modulator - - - - - - - - - - - - Pmp3 k141_21956_3 1278309.KB907100_gene1930 2.36e-107 313.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,1XJBF@135619|Oceanospirillales 135619|Oceanospirillales U UPF0056 membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_19189_1 644107.SL1157_2362 1.95e-96 287.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,4NBG6@97050|Ruegeria 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_3 k141_2414_1 765913.ThidrDRAFT_0302 8.71e-36 132.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales 135613|Chromatiales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_2414_2 1122201.AUAZ01000008_gene479 4.54e-69 218.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,465FC@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - iPC815.YPO1374 Pyr_redox_2 k141_13558_1 1001585.MDS_3052 6.46e-12 66.6 COG1082@1|root,COG1082@2|Bacteria,1Q3WR@1224|Proteobacteria,1S04R@1236|Gammaproteobacteria,1YD51@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 k141_13558_2 317025.Tcr_1800 7.97e-138 398.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_12189_1 1278309.KB907105_gene1521 1.02e-225 630.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XHQX@135619|Oceanospirillales 135619|Oceanospirillales M N-acetylmuramoyl-L-alanine amidase amiB - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_12189_2 1278309.KB907105_gene1522 0.0 1090.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XHJY@135619|Oceanospirillales 135619|Oceanospirillales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_12189_3 1278309.KB907105_gene1523 1.4e-187 524.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XHV3@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_3151_1 945543.VIBR0546_03645 3.73e-36 127.0 COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1S2UE@1236|Gammaproteobacteria,1XSJW@135623|Vibrionales 135623|Vibrionales F Gluconokinase idnK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - SKI k141_3151_2 400668.Mmwyl1_0696 2.24e-244 679.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XH7R@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM k141_3151_3 1208321.D104_07775 8.09e-74 227.0 COG4665@1|root,COG4665@2|Bacteria,1RDPJ@1224|Proteobacteria,1S4KV@1236|Gammaproteobacteria,1XKCH@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_3151_4 1208321.D104_07770 2.26e-28 110.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XJ0K@135619|Oceanospirillales 135619|Oceanospirillales Q C4-dicarboxylate ABC transporter substrate-binding protein - - - - - - - - - - - - DctP k141_10057_1 527002.yaldo0001_27940 8.13e-66 208.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,41EAZ@629|Yersinia 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD k141_336_1 1178482.BJB45_16330 1.14e-24 95.5 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XKYH@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the acylphosphatase family acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase k141_15664_1 314278.NB231_01479 0.000161 43.1 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1WWVT@135613|Chromatiales 135613|Chromatiales E PFAM peptidase M1, membrane alanine aminopeptidase pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_15664_2 439235.Dalk_5291 2.2e-53 184.0 COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,2MKQ5@213118|Desulfobacterales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_8062_1 545264.KB898759_gene2659 5.09e-146 423.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1WW9J@135613|Chromatiales 135613|Chromatiales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_4539_1 675812.VHA_001603 1.24e-06 51.2 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1RSE0@1236|Gammaproteobacteria,1XZSQ@135623|Vibrionales 135623|Vibrionales S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA k141_4539_2 391626.OAN307_c36350 1.01e-102 313.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate MA20_44990 - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_12190_1 580332.Slit_2150 3.07e-65 208.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_14960_2 1530186.JQEY01000004_gene1997 1.74e-68 213.0 COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U7C6@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides chaC - - ko:K07232 - - - - ko00000 - - - ChaC k141_1024_1 1396858.Q666_04035 3.87e-07 54.3 COG2062@1|root,COG5607@1|root,COG2062@2|Bacteria,COG5607@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,4691U@72275|Alteromonadaceae 1236|Gammaproteobacteria T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - CHAD,His_Phos_1 k141_7317_5 1288826.MSNKSG1_05181 2.98e-181 506.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,465A1@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_7317_6 1288826.MSNKSG1_05186 6.17e-142 401.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,4649H@72275|Alteromonadaceae 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_7317_7 1288826.MSNKSG1_05191 1.21e-218 604.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,463YU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_3825_2 1134474.O59_004071 2.6e-43 148.0 COG3521@1|root,COG3521@2|Bacteria,1PCDP@1224|Proteobacteria,1SAWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K11906 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS-SciN k141_5195_1 59196.RICGR_0397 1.23e-16 80.9 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1JCA9@118969|Legionellales 118969|Legionellales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_5195_2 472759.Nhal_3898 1.25e-81 251.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales 135613|Chromatiales P PFAM CBS domain - - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_13574_2 1278309.KB907099_gene2373 2.14e-52 166.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,1XMBW@135619|Oceanospirillales 135619|Oceanospirillales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_13574_3 1278309.KB907099_gene2372 0.0 878.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XHA4@135619|Oceanospirillales 135619|Oceanospirillales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_13574_4 1278309.KB907099_gene2371 1.3e-251 697.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1XHH2@135619|Oceanospirillales 135619|Oceanospirillales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_2430_1 870187.Thini_0759 2.55e-51 164.0 COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria,1SS60@1236|Gammaproteobacteria 1236|Gammaproteobacteria P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_12214_1 713586.KB900536_gene1468 1.01e-19 93.2 COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales 135613|Chromatiales S Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide k141_359_1 1163409.UUA_17250 1.61e-82 253.0 COG0583@1|root,COG0583@2|Bacteria,1MXDQ@1224|Proteobacteria,1RPBS@1236|Gammaproteobacteria,1X4DP@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator VL23_16385 - - - - - - - - - - - HTH_1,LysR_substrate k141_4549_1 1042375.AFPL01000054_gene2082 2.9e-06 49.7 COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,468Z3@72275|Alteromonadaceae 1236|Gammaproteobacteria KNU COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) flgM - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_4549_2 1278309.KB907107_gene1757 1.46e-70 217.0 COG3418@1|root,COG3418@2|Bacteria,1NEGC@1224|Proteobacteria,1SF3T@1236|Gammaproteobacteria,1XMBC@135619|Oceanospirillales 135619|Oceanospirillales NOU FlgN protein - - - - - - - - - - - - FlgN k141_4549_3 1121405.dsmv_1916 6.55e-34 139.0 COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2MJ2Z@213118|Desulfobacterales 28221|Deltaproteobacteria T GAF domain - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9 k141_1038_1 1410670.JHXF01000015_gene2310 4.88e-08 60.5 COG1961@1|root,COG1961@2|Bacteria,1V0IT@1239|Firmicutes,24E71@186801|Clostridia 186801|Clostridia L Resolvase, N terminal domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom k141_18447_2 1288826.MSNKSG1_00691 1.01e-137 392.0 COG0834@1|root,COG0834@2|Bacteria,1P96T@1224|Proteobacteria,1SUCH@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET Bacterial extracellular solute-binding proteins, family 3 - - - - - - - - - - - - SBP_bac_3 k141_18447_3 1288826.MSNKSG1_00686 1.57e-177 511.0 COG0840@1|root,COG0840@2|Bacteria,1PHEA@1224|Proteobacteria,1RX5Y@1236|Gammaproteobacteria,46B0P@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - HAMP,MCPsignal k141_17057_1 1288826.MSNKSG1_13622 5.32e-167 474.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,465D8@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_17057_2 1288826.MSNKSG1_13627 1.22e-250 689.0 COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,4669M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_17057_3 1288826.MSNKSG1_13632 1.48e-248 683.0 COG2199@1|root,COG3706@2|Bacteria,1N27P@1224|Proteobacteria,1SAKJ@1236|Gammaproteobacteria,465XJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_17057_4 1288826.MSNKSG1_13637 2.47e-221 610.0 COG0596@1|root,COG0596@2|Bacteria,1QIT9@1224|Proteobacteria,1RNP9@1236|Gammaproteobacteria,469GQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_17057_5 1288826.MSNKSG1_13642 4.09e-129 367.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,463YM@72275|Alteromonadaceae 1236|Gammaproteobacteria H GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_17057_6 1288826.MSNKSG1_13647 5.54e-82 243.0 COG1539@1|root,COG1539@2|Bacteria,1RDHQ@1224|Proteobacteria,1S4Q3@1236|Gammaproteobacteria,467FZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H dihydroneopterin aldolase folX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 5.1.99.7 ko:K07589 ko00790,map00790 - R11082 RC01479 ko00000,ko00001,ko01000 - - - FolB k141_17057_7 1288826.MSNKSG1_13652 2.58e-91 268.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,1S3T2@1236|Gammaproteobacteria,46BBD@72275|Alteromonadaceae 1236|Gammaproteobacteria S CoA-binding protein yccU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06929 - - - - ko00000 - - - CoA_binding_2 k141_17057_8 1288826.MSNKSG1_13657 2.31e-295 808.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2206 HD-GYP domain - - - - - - - - - - - - DUF3391,HD,HD_5 k141_17057_9 1288826.MSNKSG1_13662 0.0 1354.0 COG3452@1|root,COG5001@1|root,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,469BW@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - CHASE,CHASE8,EAL,GGDEF k141_17057_11 1288826.MSNKSG1_13672 1.4e-107 310.0 COG0789@1|root,COG0789@2|Bacteria,1RJD4@1224|Proteobacteria,1S8DH@1236|Gammaproteobacteria,467WR@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 k141_17057_12 1288826.MSNKSG1_13677 4.59e-222 639.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_3171_1 1298593.TOL_0003 6.64e-23 98.2 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XHRC@135619|Oceanospirillales 135619|Oceanospirillales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_11509_1 1278309.KB907109_gene3256 5.47e-135 410.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XHSP@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS k141_11509_2 1278309.KB907109_gene3255 1.69e-287 791.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XHFG@135619|Oceanospirillales 135619|Oceanospirillales T regulator hydG - - - - - - - - - - - Response_reg,Sigma54_activat k141_5925_1 1288826.MSNKSG1_07983 5.02e-32 119.0 COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,467GB@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin znuA GO:0000041,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008270,GO:0030001,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - iECs_1301.ECs2567,iEcSMS35_1347.EcSMS35_1329,iPC815.YPO2061,iZ_1308.Z2909 ZnuA k141_5925_2 1288826.MSNKSG1_07978 0.0 1013.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,464NA@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iEC042_1314.EC042_2616 tRNA-synt_1c k141_5925_4 1288826.MSNKSG1_05046 9.04e-74 241.0 COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465EN@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CHASE5,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS_4,PAS_9,Response_reg k141_360_1 765914.ThisiDRAFT_1700 1.64e-78 248.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1WVYU@135613|Chromatiales 135613|Chromatiales N ATPase FliI YscN family - - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_3894_2 1500893.JQNB01000001_gene3415 8.2e-56 177.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1X61R@135614|Xanthomonadales 135614|Xanthomonadales J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_1165_1 765912.Thimo_1515 6.33e-31 122.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1WWW0@135613|Chromatiales 135613|Chromatiales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C k141_1836_1 870187.Thini_4010 1.33e-55 186.0 COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RMV3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation nifK - 1.18.6.1 ko:K02591 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - DUF3364,Oxidored_nitro k141_1836_2 1170562.Cal6303_1162 6.29e-06 46.6 COG5554@1|root,COG5554@2|Bacteria,1G95Z@1117|Cyanobacteria,1HPZ8@1161|Nostocales 1117|Cyanobacteria Q PFAM NifT FixU nifT - - ko:K02593 - - - - ko00000 - - - NifT k141_1836_3 697282.Mettu_3331 4.5e-24 91.7 COG1145@1|root,COG1145@2|Bacteria,1N859@1224|Proteobacteria,1SEBQ@1236|Gammaproteobacteria,1XGQG@135618|Methylococcales 135618|Methylococcales C PFAM 4Fe-4S ferredoxin, iron-sulphur binding, subgroup - - - - - - - - - - - - Fer4 k141_15818_1 349124.Hhal_0133 1.77e-17 80.9 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_11584_1 713587.THITH_12355 1.46e-152 444.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA k141_10182_1 396588.Tgr7_2051 3.89e-89 273.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales 135613|Chromatiales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_22051_1 595537.Varpa_5570 8.12e-68 214.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VIYR@28216|Betaproteobacteria,4ACV9@80864|Comamonadaceae 28216|Betaproteobacteria K Two component transcriptional regulator - - - ko:K11329 ko02020,map02020 M00467 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_17145_2 754477.Q7C_783 6.46e-59 184.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,460SQ@72273|Thiotrichales 72273|Thiotrichales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 k141_20664_1 335283.Neut_1916 1.48e-48 172.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,371MA@32003|Nitrosomonadales 28216|Betaproteobacteria P TIGRFAM TonB-dependent vitamin B12 receptor btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_20664_2 1042377.AFPJ01000037_gene2873 4.32e-69 217.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,466K8@72275|Alteromonadaceae 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA k141_1183_2 1198232.CYCME_1912 8.6e-82 254.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,460BZ@72273|Thiotrichales 72273|Thiotrichales C D-isomer specific 2-hydroxyacid dehydrogenase serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_19934_1 323848.Nmul_A2472 6.26e-60 200.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_5990_1 1288826.MSNKSG1_18055 3.38e-85 253.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,467IU@72275|Alteromonadaceae 1236|Gammaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_5990_2 1288826.MSNKSG1_18050 3.16e-230 634.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,465AA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k141_5990_3 1288826.MSNKSG1_18045 0.0 1163.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,46493@72275|Alteromonadaceae 1236|Gammaproteobacteria T membrane GTPase involved in stress response typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_17903_1 1196031.ALEG01000041_gene2776 2.68e-85 261.0 COG4588@1|root,COG4588@2|Bacteria,1V65Q@1239|Firmicutes,4HUJC@91061|Bacilli,1ZE5Q@1386|Bacillus 91061|Bacilli S Bacterial extracellular solute-binding protein - - - ko:K10938 ko05111,map05111 - - - ko00000,ko00001 - - - SBP_bac_11 k141_13044_1 1089547.KB913013_gene1539 3.3e-52 189.0 COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia 976|Bacteroidetes D Motility related/secretion protein sprA - - - - - - - - - - - SprA_N k141_4664_1 1121019.AUMN01000006_gene2896 1.59e-36 139.0 COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,1W80J@1268|Micrococcaceae 201174|Actinobacteria E ATPases associated with a variety of cellular activities proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS k141_20680_1 571166.KI421509_gene2306 9.06e-59 194.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Acetylornithine aminotransferase argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_20680_2 314256.OG2516_14171 7.42e-28 108.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria,2PCZ5@252301|Oceanicola 28211|Alphaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_16456_1 1131462.DCF50_p1961 2.8e-14 76.6 COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia,2619N@186807|Peptococcaceae 186801|Clostridia L PFAM Transposase DDE domain - - - - - - - - - - - - DDE_5,DDE_Tnp_1 k141_7429_2 225937.HP15_508 3.23e-83 258.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,464V7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_1849_2 1166948.JPZL01000001_gene2581 6.15e-06 46.6 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1XK11@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin - - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_8182_1 1234364.AMSF01000027_gene3468 4.51e-105 310.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1X4J2@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_22058_1 1237149.C900_05057 2.13e-52 174.0 COG0457@1|root,COG0457@2|Bacteria,4NSYY@976|Bacteroidetes,47R4Q@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - ANAPC3,TPR_2,TPR_8 k141_3275_1 382245.ASA_1605 2.45e-59 203.0 COG1196@1|root,COG1196@2|Bacteria,1PEPJ@1224|Proteobacteria,1RQFX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Domain of unknown function (DUF4041) - - - - - - - - - - - - DUF4041,MUG113,T5orf172 k141_21400_1 1278309.KB907100_gene1971 2.47e-126 361.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XR8K@135619|Oceanospirillales 135619|Oceanospirillales KT PFAM response regulator receiver, transcriptional regulator domain-containing protein - - - - - - - - - - - - Response_reg,Trans_reg_C k141_21400_2 1278309.KB907100_gene1972 5.28e-34 120.0 28YG9@1|root,2ZKAJ@2|Bacteria,1QSIZ@1224|Proteobacteria,1RW0J@1236|Gammaproteobacteria,1XQTM@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_21400_3 1278309.KB907100_gene1973 7.14e-103 298.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1XJWN@135619|Oceanospirillales 135619|Oceanospirillales I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA k141_21400_4 1278309.KB907100_gene1974 1.56e-185 521.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1XJQV@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_21400_5 1278309.KB907100_gene1975 2.89e-98 286.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XK4R@135619|Oceanospirillales 135619|Oceanospirillales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_21400_6 1042375.AFPL01000030_gene527 9.25e-06 45.8 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,466GG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0380 DMRL_synthase k141_10198_1 1469245.JFBG01000056_gene2481 1.23e-38 133.0 COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,1WYSI@135613|Chromatiales 135613|Chromatiales C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K17223 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C,Cytochrome_CBB3 k141_6672_1 317025.Tcr_0960 1.27e-39 140.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,460E4@72273|Thiotrichales 72273|Thiotrichales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_6672_2 768671.ThimaDRAFT_1391 1.55e-66 207.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales 135613|Chromatiales S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate - - 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_3 k141_4665_1 367336.OM2255_03835 1.31e-92 282.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_5347_2 765912.Thimo_2794 1.08e-42 152.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales 135613|Chromatiales K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_17904_2 1278309.KB907099_gene2933 4.48e-93 286.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_5,Pyr_redox_3 k141_12341_1 1288826.MSNKSG1_00958 6.02e-79 240.0 COG2430@1|root,COG2430@2|Bacteria,1REND@1224|Proteobacteria,1S94F@1236|Gammaproteobacteria,4681T@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF432 k141_12341_2 1288826.MSNKSG1_00953 0.0 923.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,4651X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family phrB GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_12341_3 1288826.MSNKSG1_00948 9.39e-170 475.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - iECIAI1_1343.ECIAI1_0865,iECW_1372.ECW_m0884,iEKO11_1354.EKO11_3059,iETEC_1333.ETEC_0893,iEcE24377_1341.EcE24377A_0897,iEcSMS35_1347.EcSMS35_0851,iWFL_1372.ECW_m0884 ThiF k141_12341_4 1288826.MSNKSG1_00943 7.72e-178 498.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,466CN@72275|Alteromonadaceae 1236|Gammaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 k141_12341_5 1288826.MSNKSG1_00938 1.27e-248 684.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,464HV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_12341_6 1288826.MSNKSG1_00933 3.77e-275 755.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,463YI@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_1850_1 933262.AXAM01000018_gene1009 2.76e-29 118.0 COG0501@1|root,COG3063@1|root,COG0501@2|Bacteria,COG3063@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria,2MIHI@213118|Desulfobacterales 28221|Deltaproteobacteria O PFAM peptidase - - - - - - - - - - - - Peptidase_M48,TPR_11,TPR_17 k141_20681_1 1209072.ALBT01000033_gene1723 2.36e-14 79.0 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1FHH9@10|Cellvibrio 1236|Gammaproteobacteria NU Type IV Pilus-assembly protein W pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_13727_1 1517681.HW45_08050 5.56e-127 371.0 COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,1RQ0R@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnD GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - ko:K13014 ko00520,ko01503,map00520,map01503 M00721,M00761 R07662 RC00323,RC01575 ko00000,ko00001,ko00002,ko01000,ko01005 - - iB21_1397.B21_02141,iBWG_1329.BWG_2029,iEC042_1314.EC042_2499,iECBD_1354.ECBD_1403,iECB_1328.ECB_02182,iECDH10B_1368.ECDH10B_2416,iECDH1ME8569_1439.ECDH1ME8569_2192,iECD_1391.ECD_02182,iECO103_1326.ECO103_2722,iECO111_1330.ECO111_3006,iECO26_1355.ECO26_3246,iECUMN_1333.ECUMN_2597,iECW_1372.ECW_m2447,iEKO11_1354.EKO11_1508,iETEC_1333.ETEC_2390,iEcDH1_1363.EcDH1_1402,iEcHS_1320.EcHS_A2401,iEcolC_1368.EcolC_1393,iJO1366.b2256,iSFV_1184.SFV_2326,iSSON_1240.SSON_2317,iUMNK88_1353.UMNK88_2808,iWFL_1372.ECW_m2447,iY75_1357.Y75_RS11830 Polysacc_deac_1 k141_14345_2 396588.Tgr7_1299 4.24e-82 248.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_19935_1 391615.ABSJ01000054_gene1465 2.9e-93 286.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1J4NS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_3276_1 1278309.KB907101_gene390 2.25e-102 310.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XH5Z@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_19315_1 1026882.MAMP_00019 2.63e-46 155.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,460DQ@72273|Thiotrichales 72273|Thiotrichales U MotA TolQ ExbB proton channel - - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_19315_2 999141.GME_16097 1.02e-33 122.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1XKER@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_10199_1 509635.N824_03675 1.14e-66 224.0 COG0438@1|root,COG1331@1|root,COG0438@2|Bacteria,COG1331@2|Bacteria,4NEW7@976|Bacteroidetes,1IQBW@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_10934_1 207954.MED92_07821 2.16e-91 268.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,1XJWV@135619|Oceanospirillales 135619|Oceanospirillales P Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide - - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase k141_10934_2 1278309.KB907106_gene1225 8.33e-170 475.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1XHI5@135619|Oceanospirillales 135619|Oceanospirillales I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_10934_3 1278309.KB907106_gene1226 3.22e-129 383.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales 135619|Oceanospirillales M gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_16458_1 396588.Tgr7_2196 1.32e-101 306.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales 135613|Chromatiales C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_9435_2 1278309.KB907101_gene538 1.06e-73 221.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,1XK69@135619|Oceanospirillales 135619|Oceanospirillales C Membrane-anchoring subunit of succinate dehydrogenase (SDH) sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_9435_3 1278309.KB907101_gene537 6.01e-48 154.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,1XKF6@135619|Oceanospirillales 135619|Oceanospirillales C succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_4666_1 931277.C448_15199 6.46e-38 142.0 COG0281@1|root,arCOG00853@2157|Archaea,2XSTN@28890|Euryarchaeota,23SK1@183963|Halobacteria 183963|Halobacteria C COG0281 Malic enzyme maeB1 - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic k141_8184_1 700015.Corgl_0299 1.09e-06 56.6 COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_17165_1 96561.Dole_0645 3.19e-29 121.0 COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,43BQW@68525|delta/epsilon subdivisions 1224|Proteobacteria T PFAM GGDEF domain containing protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - AAA_16,CHASE2,GAF,GAF_2,GGDEF,Hpt,PAS,Pkinase,Response_reg,SBP_bac_3 k141_17165_2 519989.ECTPHS_02546 7.44e-20 84.7 2CEDU@1|root,333S9@2|Bacteria,1NI7T@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4156) - - - - - - - - - - - - DUF4156 k141_473_1 1288826.MSNKSG1_09033 1.29e-159 450.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,464DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Displays ATPase and GTPase activities rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_473_2 1288826.MSNKSG1_09038 2.8e-52 165.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,468BC@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1925 Phosphotransferase system, HPr-related proteins ptsO GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - ko:K08485,ko:K11189 ko02060,map02060 - - - ko00000,ko00001,ko02000 4.A.2.1 - - PTS-HPr k141_473_3 1288826.MSNKSG1_09043 3.63e-93 284.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,4641S@72275|Alteromonadaceae 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_20682_1 314271.RB2654_04721 6.77e-83 258.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria 28211|Alphaproteobacteria H COG0303 Molybdopterin biosynthesis enzyme moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_18562_1 768671.ThimaDRAFT_2216 2.38e-70 215.0 COG2143@1|root,COG2143@2|Bacteria,1N6H1@1224|Proteobacteria,1SQSZ@1236|Gammaproteobacteria,1X16R@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - - - - - - - - - - - k141_18562_2 768671.ThimaDRAFT_2215 8.55e-124 372.0 2C76Q@1|root,30D3Y@2|Bacteria,1RF8T@1224|Proteobacteria,1SPGW@1236|Gammaproteobacteria,1X0W0@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_7432_1 1535422.ND16A_1845 5.11e-51 167.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria 1236|Gammaproteobacteria C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters nifU - - ko:K04488 - - - - ko00000 - - - NifU_N k141_9436_1 1162668.LFE_0420 1.37e-13 67.8 COG0784@1|root,COG0784@2|Bacteria 2|Bacteria T Response regulator, receiver rcp1 - - ko:K02485,ko:K11355 ko02020,map02020 M00510 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg k141_9436_2 1297742.A176_04658 7.14e-81 264.0 COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2YYPF@29|Myxococcales 28221|Deltaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4 k141_16459_2 522306.CAP2UW1_4008 2.08e-45 147.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,1KQX1@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C 4Fe-4S binding domain fdx1 - - - - - - - - - - - Fer4,Fer4_7 k141_16459_3 983545.Glaag_0058 5.93e-61 192.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,466Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0053,iSDY_1059.SDY_4064 CTP_transf_like k141_8769_1 1288826.MSNKSG1_04246 0.0 1116.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Phosphoketolase xfp GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_8769_2 1288826.MSNKSG1_04241 4e-300 821.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,4640Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_8769_3 1288826.MSNKSG1_04236 0.0 1554.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0474 Cation transport ATPase - - 3.6.3.6 ko:K01535,ko:K12955 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.24,3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_8769_4 1288826.MSNKSG1_04231 2.45e-112 323.0 COG3794@1|root,COG3794@2|Bacteria,1QWIK@1224|Proteobacteria 1224|Proteobacteria C CHRD domain - - - - - - - - - - - - CHRD k141_10342_4 1415778.JQMM01000001_gene468 1.15e-56 179.0 COG4647@1|root,COG4647@2|Bacteria,1N485@1224|Proteobacteria,1S2W4@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Acetone carboxylase gamma subunit - - 6.4.1.6 ko:K10856 - - - - ko00000,ko01000 - - - Acetone_carb_G k141_582_1 85643.Tmz1t_1543 6.77e-31 114.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales 206389|Rhodocyclales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_582_2 1333856.L686_07580 1.33e-29 107.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1Z38N@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_5483_1 713586.KB900536_gene819 5.22e-09 57.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales 135613|Chromatiales S PFAM Uncharacterised protein family UPF0027 rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_5483_2 1122221.JHVI01000007_gene2198 1.88e-50 166.0 COG1371@1|root,COG1371@2|Bacteria 2|Bacteria J PFAM Archease protein family (DUF101 UPF0211) - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Archease k141_8302_1 1122599.AUGR01000012_gene865 2.86e-88 273.0 COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XNIC@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - Aminotran_1_2,GntR k141_8302_2 595537.Varpa_2419 3.48e-82 248.0 COG0693@1|root,COG0693@2|Bacteria,1MYS4@1224|Proteobacteria,2VHFV@28216|Betaproteobacteria,4ADGE@80864|Comamonadaceae 28216|Betaproteobacteria S ThiJ PfpI - - - - - - - - - - - - DJ-1_PfpI k141_13851_1 189753.AXAS01000017_gene3068 1.42e-15 82.4 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,2U0R7@28211|Alphaproteobacteria,3JRHD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - Yop-YscD_cpl k141_13851_2 1123399.AQVE01000009_gene3041 9.98e-76 249.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,1RRAD@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 k141_13851_3 395493.BegalDRAFT_0531 1.72e-25 106.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales 72273|Thiotrichales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_3392_1 247639.MGP2080_15074 8.35e-13 65.1 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Sulphur oxidation protein SoxZ soxZ - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ k141_3392_2 317025.Tcr_2158 1.55e-29 112.0 COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,1S6P0@1236|Gammaproteobacteria,462TC@72273|Thiotrichales 72273|Thiotrichales S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_3392_3 396588.Tgr7_0038 2.19e-55 188.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_19412_1 1131553.JIBI01000044_gene1397 2.54e-186 539.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,372DE@32003|Nitrosomonadales 28216|Betaproteobacteria G aldehyde-lyase activity xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_1966_1 744979.R2A130_3419 1.29e-36 130.0 COG1802@1|root,COG1802@2|Bacteria,1MXNF@1224|Proteobacteria,2U1PK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Regulatory protein GntR HTH MA20_15070 - - - - - - - - - - - FCD,GntR k141_1966_2 467661.RKLH11_3257 1.67e-12 64.7 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2U9MT@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG1335 Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_2650_1 634500.EbC_18250 2.74e-62 201.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,3X4RB@551|Erwinia 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N k141_18066_1 1278309.KB907100_gene2033 3.65e-103 305.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1XJEC@135619|Oceanospirillales 135619|Oceanospirillales S Ser threonine protein phosphatase - - - - - - - - - - - - Metallophos,Metallophos_2 k141_21518_1 1283300.ATXB01000001_gene1115 1.36e-49 159.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1XF9W@135618|Methylococcales 135618|Methylococcales E PFAM Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_21518_2 977880.RALTA_A2865 2.41e-35 124.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,1K7XK@119060|Burkholderiaceae 28216|Betaproteobacteria FG PFAM histidine triad (HIT) protein hitA - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_11066_2 1278309.KB907099_gene2543 2.21e-119 345.0 2DDIQ@1|root,2ZI8W@2|Bacteria,1RB6W@1224|Proteobacteria,1S289@1236|Gammaproteobacteria,1XNFJ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11066_3 1278309.KB907099_gene2544 5.67e-279 764.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1XH70@135619|Oceanospirillales 135619|Oceanospirillales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_10343_1 1122603.ATVI01000007_gene1619 1.68e-81 258.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1X4BH@135614|Xanthomonadales 135614|Xanthomonadales P chloride channel clcA - - - - - - - - - - - Voltage_CLC k141_16593_1 529507.PMI1047 3.58e-05 52.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,3Z1IM@583|Proteus 1236|Gammaproteobacteria I Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnT - 2.4.2.43 ko:K07264 ko01503,map01503 M00721 R09773,R09774,R09781 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - - - PMT k141_16593_2 880074.BARVI_11390 5.85e-08 54.7 COG2076@1|root,COG2076@2|Bacteria 2|Bacteria P Multidrug Resistance protein arnE - - ko:K12962 ko01503,map01503 M00721 - - ko00000,ko00001,ko00002,ko01005,ko02000 2.A.7.22 - - EamA,Multi_Drug_Res k141_16593_3 425104.Ssed_0920 4.08e-17 79.0 COG2076@1|root,COG2076@2|Bacteria,1N7ZX@1224|Proteobacteria,1SCDW@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane arnF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K12963 ko01503,map01503 M00721 - - ko00000,ko00001,ko00002,ko01005 2.A.7 - iECUMN_1333.ECUMN_2601,iSF_1195.SF2337,iS_1188.S2471 EamA,Multi_Drug_Res k141_22191_1 1117318.PRUB_01354 5.27e-64 200.0 COG0454@1|root,COG0456@2|Bacteria,1N81E@1224|Proteobacteria,1S8BD@1236|Gammaproteobacteria,2Q362@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_583_1 870187.Thini_2039 2.53e-52 174.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,4605Y@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_583_2 1117647.M5M_11840 4.2e-07 51.6 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1J612@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yigA - - ko:K09921 - - - - ko00000 - - - DUF484 k141_4796_1 1337093.MBE-LCI_1925 5.86e-59 185.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 k141_15951_1 580332.Slit_1617 3.52e-263 734.0 COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the NiFe NiFeSe hydrogenase large subunit family - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases k141_5484_1 697282.Mettu_3162 3.16e-45 167.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_7543_1 1278309.KB907100_gene2272 3.65e-94 288.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XHSI@135619|Oceanospirillales 135619|Oceanospirillales P Trk system potassium uptake protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_7543_2 1278309.KB907100_gene2271 6.57e-295 809.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1XICQ@135619|Oceanospirillales 135619|Oceanospirillales P found to be peripherally associated with the inner membrane in Escherichia coli trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_7543_3 1278309.KB907100_gene2270 7.53e-251 695.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1XHIS@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_7543_4 1278309.KB907100_gene2269 3.77e-70 220.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XIP5@135619|Oceanospirillales 135619|Oceanospirillales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_8304_1 1163617.SCD_n01410 1.16e-93 285.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria 28216|Betaproteobacteria G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 k141_16594_2 768670.Calni_1836 1.39e-16 82.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2GF7H@200930|Deferribacteres 200930|Deferribacteres T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_22192_1 1121875.KB907550_gene636 8.83e-92 286.0 COG2015@1|root,COG2015@2|Bacteria,4NJE2@976|Bacteroidetes 976|Bacteroidetes Q Alkyl sulfatase dimerisation - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_13852_1 1026882.MAMP_00483 6.53e-21 95.5 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,4619H@72273|Thiotrichales 72273|Thiotrichales H HemX, putative uroporphyrinogen-III C-methyltransferase - - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX k141_17289_1 1123392.AQWL01000007_gene984 2.89e-52 177.0 COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,2VJFD@28216|Betaproteobacteria,1KRCB@119069|Hydrogenophilales 119069|Hydrogenophilales P FAD-binding domain - - - - - - - - - - - - FAD_binding_8,Ferric_reduct k141_17289_2 1479237.JMLY01000001_gene3665 2.42e-223 621.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RR0P@1236|Gammaproteobacteria,464S1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain glnT - 6.3.1.11,6.3.1.2 ko:K01915,ko:K09470 ko00220,ko00250,ko00330,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00330,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 M00136 R00253,R07414 RC00010,RC00090,RC00096,RC02798 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Gln-synt_C k141_13170_1 396588.Tgr7_2123 1.34e-103 319.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_3393_1 1121440.AUMA01000020_gene1967 9.78e-15 76.6 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,2M9KT@213115|Desulfovibrionales 28221|Deltaproteobacteria HJ Belongs to the D-alanine--D-alanine ligase family - - - - - - - - - - - - Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK k141_3393_2 1283300.ATXB01000001_gene2076 5.62e-102 307.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1XEX3@135618|Methylococcales 135618|Methylococcales K Peptidase_C39 like family - - - - - - - - - - - - Acetyltransf_1,DUF3335 k141_21519_1 1286106.MPL1_04872 3.93e-98 294.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,46077@72273|Thiotrichales 72273|Thiotrichales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_1967_1 84588.SYNW1696 3.33e-48 171.0 COG3239@1|root,COG3239@2|Bacteria,1G26Y@1117|Cyanobacteria,1GZXA@1129|Synechococcus 1117|Cyanobacteria I fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_8882_2 519989.ECTPHS_13123 3.39e-45 148.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1WYNJ@135613|Chromatiales 135613|Chromatiales J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_8882_3 998088.B565_0197 9e-59 184.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1Y4DI@135624|Aeromonadales 135624|Aeromonadales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_8882_4 930169.B5T_03780 6.43e-79 239.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1XJA3@135619|Oceanospirillales 135619|Oceanospirillales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_11086_3 1049564.TevJSym_aj00710 3.16e-202 584.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Von willebrand factor, type a cbbO - - - - - - - - - - - VWA k141_20024_1 1288826.MSNKSG1_03101 2.61e-78 243.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,464MG@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 DXPR_C,DXP_redisom_C,DXP_reductoisom k141_20024_2 1288826.MSNKSG1_03096 4.15e-194 539.0 COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,1T63B@1236|Gammaproteobacteria,46DFC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_20024_3 1288826.MSNKSG1_03091 6.37e-182 506.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,4654U@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880 Prenyltransf k141_20024_4 1288826.MSNKSG1_03086 3.49e-119 342.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,466FX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_20024_5 1288826.MSNKSG1_03081 4.83e-170 475.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,465IM@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_20024_6 1288826.MSNKSG1_03076 3.91e-188 525.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,464QB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_20024_7 1288826.MSNKSG1_03071 1.96e-173 484.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,46443@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_20024_8 1288826.MSNKSG1_03066 2.24e-191 530.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,46498@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_20024_9 1288826.MSNKSG1_03061 0.0 905.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_19427_1 644076.SCH4B_3202 2.56e-52 178.0 COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2TSUM@28211|Alphaproteobacteria,4NABI@97050|Ruegeria 28211|Alphaproteobacteria H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_19427_2 391593.RCCS2_06964 7.15e-06 46.2 COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9AJ@28211|Alphaproteobacteria,2P3T7@2433|Roseobacter 28211|Alphaproteobacteria P COG0607 Rhodanese-related sulfurtransferase - - - - - - - - - - - - Rhodanese k141_2667_1 367336.OM2255_03615 4.57e-120 375.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_3417_1 1122137.AQXF01000002_gene349 1.12e-103 324.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_17306_1 371731.Rsw2DRAFT_1055 7.19e-37 140.0 COG0168@1|root,COG0168@2|Bacteria,1MWV4@1224|Proteobacteria,2TQP5@28211|Alphaproteobacteria,1FCJT@1060|Rhodobacter 28211|Alphaproteobacteria P PFAM Cation trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_11087_1 1415779.JOMH01000001_gene947 3.97e-32 122.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X5XT@135614|Xanthomonadales 135614|Xanthomonadales S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 k141_11087_2 1415780.JPOG01000001_gene3004 1.48e-09 60.5 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1XCE4@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_20766_1 666684.AfiDRAFT_1751 1.07e-39 137.0 2ED3M@1|root,3370H@2|Bacteria,1NB6I@1224|Proteobacteria,2UE8V@28211|Alphaproteobacteria,3K53J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_20766_2 1219375.CM002139_gene1663 4.41e-38 144.0 COG0583@1|root,COG0583@2|Bacteria,1MXDQ@1224|Proteobacteria,1RPBS@1236|Gammaproteobacteria,1X4DP@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator VL23_16385 - - - - - - - - - - - HTH_1,LysR_substrate k141_20766_3 83406.HDN1F_07480 0.0002 45.8 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_4806_1 1158760.AQXP01000055_gene1297 8.82e-42 147.0 COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales 135613|Chromatiales P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k141_4806_2 32042.PstZobell_15289 2.44e-08 58.2 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z2MH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_6136_1 1286106.MPL1_01583 2.05e-32 117.0 COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,463BK@72273|Thiotrichales 72273|Thiotrichales K Transcriptional regulator - - - - - - - - - - - - HTH_24 k141_6136_2 203120.LEUM_1589 3.57e-08 55.8 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,4AXS2@81850|Leuconostocaceae 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB k141_15168_1 314278.NB231_05025 1.4e-67 217.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales 135613|Chromatiales S Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_13191_2 1535422.ND16A_2484 3.08e-57 187.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,2Q6RW@267889|Colwelliaceae 1236|Gammaproteobacteria C FMN_bind rnfG GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0009279,GO:0016020,GO:0016491,GO:0016651,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0055114,GO:0071944 - ko:K03612 - - - - ko00000 - - - FMN_bind k141_3418_1 644107.SL1157_2207 3.77e-47 158.0 COG0483@1|root,COG0483@2|Bacteria,1R3TP@1224|Proteobacteria,2U4FB@28211|Alphaproteobacteria,4NCEX@97050|Ruegeria 28211|Alphaproteobacteria G Belongs to the inositol monophosphatase superfamily - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_3418_2 644107.SL1157_2209 8.7e-22 92.8 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4NCZT@97050|Ruegeria 28211|Alphaproteobacteria E TOBE domain fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_13868_1 439235.Dalk_0268 4.19e-83 264.0 COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1 k141_10359_1 395493.BegalDRAFT_2359 6.65e-47 159.0 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales 72273|Thiotrichales S Peptidase M50 - - - - - - - - - - - - Peptidase_M50 k141_10359_2 1395571.TMS3_0103085 9.19e-34 123.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S YbaK prolyl-tRNA synthetase associated - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_1333_1 1278309.KB907099_gene2556 2.6e-106 313.0 COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,1RNDJ@1236|Gammaproteobacteria,1XI3F@135619|Oceanospirillales 135619|Oceanospirillales Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds - - 1.2.1.10,1.2.1.87 ko:K04073,ko:K18366 ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220 M00545,M00569 R00228,R01172,R09097 RC00004,RC00184,RC01195 br01602,ko00000,ko00001,ko00002,ko01000 - - - AcetDehyd-dimer,Semialdhyde_dh k141_18732_1 207954.MED92_08495 6.72e-50 174.0 COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,1RP0X@1236|Gammaproteobacteria,1XH6U@135619|Oceanospirillales 135619|Oceanospirillales M COG0845 Membrane-fusion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_17307_1 1286106.MPL1_09100 8.76e-26 104.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,45ZPX@72273|Thiotrichales 72273|Thiotrichales H Belongs to the ALAD family - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_592_1 1173023.KE650771_gene2662 9.6e-24 99.4 COG4067@1|root,COG4067@2|Bacteria,1GJIW@1117|Cyanobacteria,1JJ2Y@1189|Stigonemataceae 1117|Cyanobacteria O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_592_2 637905.SVI_0385 4.81e-52 178.0 COG0607@1|root,COG0607@2|Bacteria,1RM2N@1224|Proteobacteria,1S8IB@1236|Gammaproteobacteria,2QD6M@267890|Shewanellaceae 1236|Gammaproteobacteria M Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_592_4 357804.Ping_2544 1.01e-36 130.0 COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria 1224|Proteobacteria Q PFAM Methyltransferase type - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_14467_1 1485545.JQLW01000005_gene1170 1.95e-43 149.0 2EHTJ@1|root,33BJ7@2|Bacteria,1NHGC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_14467_2 1122201.AUAZ01000005_gene625 1.63e-230 665.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,464J4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_13192_2 1120956.JHZK01000003_gene210 2.14e-21 85.5 COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,2UFTD@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 k141_11790_2 1123518.ARWI01000001_gene537 4.16e-61 196.0 COG1082@1|root,COG1082@2|Bacteria,1Q3WR@1224|Proteobacteria,1S04R@1236|Gammaproteobacteria,461MT@72273|Thiotrichales 72273|Thiotrichales G Xylose isomerase - - - - - - - - - - - - - k141_15267_1 1279019.ARQK01000061_gene1794 1.3e-29 110.0 COG3011@1|root,COG3011@2|Bacteria,1PV30@1224|Proteobacteria,1SCCX@1236|Gammaproteobacteria,1WZJ7@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_15267_2 582744.Msip34_1299 1.4e-15 75.9 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,2KP5H@206350|Nitrosomonadales 206350|Nitrosomonadales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_6874_1 438753.AZC_4686 8.85e-24 96.3 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,3F168@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Nitroreductase family rutE - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k141_6874_2 1121380.JNIW01000023_gene160 1.06e-09 58.9 COG1403@1|root,COG1403@2|Bacteria,1WN6H@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V HNH endonuclease - - - - - - - - - - - - - k141_6874_3 1408254.T458_20420 6.48e-48 172.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,26UHN@186822|Paenibacillaceae 91061|Bacilli E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k141_20112_2 1288826.MSNKSG1_02003 1.14e-80 239.0 2B2JB@1|root,32XJW@2|Bacteria,1MZQH@1224|Proteobacteria,1SB5E@1236|Gammaproteobacteria,46DN6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2750) - - - - - - - - - - - - DUF2750 k141_9703_1 1288826.MSNKSG1_08113 1.39e-118 345.0 2ECVF@1|root,336ST@2|Bacteria,1NZ5X@1224|Proteobacteria,1SQ0V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9703_2 1288826.MSNKSG1_08108 1.56e-153 432.0 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,467NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator psrA - - - - - - - - - - - TetR_N k141_9703_3 1288826.MSNKSG1_08103 2.45e-112 323.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,46AXI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - YkuD k141_9703_4 1288826.MSNKSG1_08098 1.05e-272 748.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,464I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_9703_5 1288826.MSNKSG1_08093 2.5e-186 518.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,4679X@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine xapA GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006148,GO:0006149,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008617,GO:0009056,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009987,GO:0015949,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0022607,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0042454,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046094,GO:0046102,GO:0046115,GO:0046121,GO:0046122,GO:0046124,GO:0046128,GO:0046130,GO:0046483,GO:0046700,GO:0047724,GO:0047975,GO:0051259,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658,GO:1903227,GO:1903228 2.4.2.1,2.4.2.28,2.4.2.44 ko:K00772,ko:K03783,ko:K03815,ko:K19696 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R09668,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO1171,iUMN146_1321.UM146_04590,iUTI89_1310.UTI89_C2739 PNP_UDP_1 k141_9703_6 1288826.MSNKSG1_08088 2.42e-176 494.0 2DS5V@1|root,33EPB@2|Bacteria,1NAH5@1224|Proteobacteria,1SHNM@1236|Gammaproteobacteria,4682H@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV k141_4138_1 933262.AXAM01000115_gene1528 3.48e-19 85.5 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WMDZ@28221|Deltaproteobacteria,2MIR0@213118|Desulfobacterales 28221|Deltaproteobacteria P Cation efflux family - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_4138_2 1278309.KB907101_gene771 1.35e-110 322.0 COG0791@1|root,COG0791@2|Bacteria,1QX3A@1224|Proteobacteria,1T35K@1236|Gammaproteobacteria,1XN2I@135619|Oceanospirillales 135619|Oceanospirillales M Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - - - - - - - - - - Peptidase_C92 k141_11847_1 713586.KB900536_gene1264 8.74e-51 170.0 COG0121@1|root,COG0121@2|Bacteria,1PX9X@1224|Proteobacteria,1SBGN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutamine amidotransferase egtC - - - - - - - - - - - GATase_4 k141_15316_1 1234364.AMSF01000027_gene3490 2.63e-23 100.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1X4IU@135614|Xanthomonadales 135614|Xanthomonadales S Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_15316_2 391008.Smal_2897 3.7e-34 126.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1X636@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0307 family - - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_9754_1 367336.OM2255_06315 4.71e-70 236.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria 28211|Alphaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_9755_2 270374.MELB17_16908 2.59e-43 149.0 COG3473@1|root,COG3473@2|Bacteria,1MU9Z@1224|Proteobacteria,1SKCG@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Asp/Glu/Hydantoin racemase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race k141_6949_1 1278309.KB907112_gene3333 1.24e-216 603.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,1XIHD@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_6949_2 1278309.KB907112_gene3334 3.07e-116 335.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,1XJ6P@135619|Oceanospirillales 135619|Oceanospirillales S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 k141_6949_3 1278309.KB907112_gene3335 4.04e-137 395.0 COG0639@1|root,COG0639@2|Bacteria,1PXN4@1224|Proteobacteria,1S0Z4@1236|Gammaproteobacteria,1XIYE@135619|Oceanospirillales 135619|Oceanospirillales T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_6949_4 1278309.KB907112_gene3336 3.81e-232 647.0 COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria,1RP4J@1236|Gammaproteobacteria,1XI0G@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_11848_2 1163617.SCD_n01209 0.0 1287.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.6 ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_6951_2 314345.SPV1_09974 3.69e-87 266.0 COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria 1224|Proteobacteria L single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - - - - - - - - - - DHHA1 k141_4140_1 1288826.MSNKSG1_03817 0.0 1650.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,464EF@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k141_4140_2 1288826.MSNKSG1_03822 2.67e-70 211.0 COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria,467S4@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K11022 ko05134,map05134 - - - ko00000,ko00001,ko02042 - - - - k141_6952_2 686340.Metal_3944 1.22e-161 461.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XDVM@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k141_6953_1 395493.BegalDRAFT_2303 1.14e-33 117.0 COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria 1236|Gammaproteobacteria O TIGRFAM hydrogenase assembly chaperone hypC hupF hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC k141_6953_2 395493.BegalDRAFT_2304 5.64e-43 144.0 COG0375@1|root,COG0375@2|Bacteria,1PTY8@1224|Proteobacteria,1SXX3@1236|Gammaproteobacteria,4637G@72273|Thiotrichales 72273|Thiotrichales S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - ko:K04651 - - - - ko00000,ko03110 - - - HypA k141_6954_1 395493.BegalDRAFT_3202 9.25e-42 149.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,461GU@72273|Thiotrichales 72273|Thiotrichales C Nickel-dependent hydrogenase - - 1.12.1.2 ko:K00436 - - R00700 - ko00000,ko01000 - - - NiFeSe_Hases k141_6954_2 243159.AFE_0938 1.56e-30 114.0 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,2NCVE@225057|Acidithiobacillales 225057|Acidithiobacillales C NADH ubiquinone oxidoreductase, 20 Kd subunit - - - - - - - - - - - - Oxidored_q6 k141_15318_1 1168065.DOK_17760 2.89e-272 762.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1J5DB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_15318_2 866536.Belba_0705 3.49e-23 103.0 COG3391@1|root,COG3391@2|Bacteria,4PKC0@976|Bacteroidetes,47Y3T@768503|Cytophagia 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - - k141_15318_3 1121935.AQXX01000120_gene4868 4.54e-32 125.0 COG3655@1|root,COG3655@2|Bacteria,1N2EA@1224|Proteobacteria,1THAM@1236|Gammaproteobacteria,1XPKT@135619|Oceanospirillales 135619|Oceanospirillales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_26 k141_15318_4 1232683.ADIMK_3590 3.33e-49 169.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,4645M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Reductase C-terminal alkT - 1.18.1.1,1.18.1.3 ko:K00529,ko:K21738 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C k141_4141_1 1288826.MSNKSG1_14082 1.12e-187 522.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,4664C@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_4141_2 1288826.MSNKSG1_14087 3.49e-95 279.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,466ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria S TQO small subunit DoxD - - - ko:K15977 - - - - ko00000 - - - DoxX k141_4141_3 1288826.MSNKSG1_14092 3.53e-154 436.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,464T8@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_15319_1 1255043.TVNIR_2988 6.32e-176 504.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA k141_6958_1 1288826.MSNKSG1_16636 6.37e-213 600.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,465CJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2200 FOG EAL domain - - - - - - - - - - - - CBS,EAL,GGDEF k141_4143_1 713586.KB900536_gene3055 1.62e-186 531.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales 135613|Chromatiales C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_15320_1 1499967.BAYZ01000061_gene5979 2.26e-06 54.7 COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria 2|Bacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_20167_1 1288826.MSNKSG1_04086 0.0 983.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,463YC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Anticodon_1,tRNA-synt_1g,tRNA_bind k141_20167_2 1288826.MSNKSG1_04091 2.72e-261 716.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4647M@72275|Alteromonadaceae 1236|Gammaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_20167_4 1288826.MSNKSG1_04101 4.2e-136 385.0 COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,466TV@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yjaG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09891 - - - - ko00000 - - - DUF416 k141_20167_5 1288826.MSNKSG1_04106 1.21e-303 828.0 COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,4662W@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase avtA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.66 ko:K00835 ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130 - R01215 RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - iEKO11_1354.EKO11_0154,iEcSMS35_1347.EcSMS35_3895 Aminotran_1_2 k141_20167_6 1288826.MSNKSG1_04111 1.36e-164 462.0 2DM1B@1|root,319Y2@2|Bacteria,1NBKI@1224|Proteobacteria,1S45V@1236|Gammaproteobacteria,467T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k141_20167_7 1288826.MSNKSG1_04116 1.57e-155 436.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,466JV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050 Formyl_trans_N k141_20167_8 1288826.MSNKSG1_04121 2.81e-257 705.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4644R@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2340 AIRS,AIRS_C k141_20167_9 1288826.MSNKSG1_04126 6.46e-247 685.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_20168_1 1288826.MSNKSG1_08788 4.41e-114 332.0 COG3765@1|root,COG3765@2|Bacteria,1N2QS@1224|Proteobacteria,1SAAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Chain length determinant protein - - - - - - - - - - - - Wzz k141_15322_1 1175306.GWL_35550 2.67e-51 177.0 COG2199@1|root,COG3159@1|root,COG3159@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WEJC@28216|Betaproteobacteria,478X6@75682|Oxalobacteraceae 28216|Betaproteobacteria T GGDEF domain - - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - DUF484,GGDEF k141_20170_1 1122929.KB908215_gene592 5.25e-103 309.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2TU42@28211|Alphaproteobacteria 28211|Alphaproteobacteria M UDP-N-acetylglucosamine 2-epimerase - - 3.2.1.183,5.1.3.14 ko:K01791,ko:K08068 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_6959_1 1288826.MSNKSG1_00446 0.0 1246.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,464KX@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase k141_6959_2 1288826.MSNKSG1_00441 1.63e-112 322.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,466GK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_6959_3 1288826.MSNKSG1_00436 1.52e-73 221.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,467TU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_6959_4 1288826.MSNKSG1_00431 2.61e-120 345.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,46745@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 ko:K00969,ko:K01488 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 CTP_transf_like k141_20172_1 519989.ECTPHS_11085 6.17e-63 206.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1WWHF@135613|Chromatiales 135613|Chromatiales EGP Major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_6960_1 1366046.HIMB11_01181 4.47e-58 189.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2V9BQ@28211|Alphaproteobacteria,3ZIEB@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria M NeuB family - - - - - - - - - - - - NeuB,SAF k141_6960_2 314232.SKA53_08306 2.58e-11 62.8 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2TU42@28211|Alphaproteobacteria 28211|Alphaproteobacteria M UDP-N-acetylglucosamine 2-epimerase - - 3.2.1.183,5.1.3.14 ko:K01791,ko:K08068 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_15325_2 1348114.OM33_02030 7.55e-39 140.0 COG1246@1|root,COG1246@2|Bacteria,1QVUT@1224|Proteobacteria,1T2JM@1236|Gammaproteobacteria,2Q5GJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C k141_15325_3 882.DVU_3251 7.05e-29 108.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,42RSQ@68525|delta/epsilon subdivisions,2WNED@28221|Deltaproteobacteria,2MBBZ@213115|Desulfovibrionales 28221|Deltaproteobacteria T HPP family - - - ko:K07168 - - - - ko00000 - - - HPP k141_15326_1 1278309.KB907102_gene17 1.1e-149 435.0 COG0175@1|root,COG3415@1|root,COG0175@2|Bacteria,COG3415@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1XHRR@135619|Oceanospirillales 135619|Oceanospirillales EH Phosphoadenosine phosphosulfate reductase family - - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_20174_1 396588.Tgr7_2158 6.66e-117 351.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales 135613|Chromatiales E TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_6961_1 396588.Tgr7_1455 1.18e-175 518.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1WW51@135613|Chromatiales 135613|Chromatiales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_6962_1 561230.PC1_0947 6.16e-13 71.6 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1MS6K@122277|Pectobacterium 1236|Gammaproteobacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1596,iSDY_1059.SDY_0191 CTP_transf_1 k141_6962_2 1122951.ATUE01000007_gene786 0.000205 43.1 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,3NIW6@468|Moraxellaceae 1236|Gammaproteobacteria H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880 Prenyltransf k141_15327_1 870187.Thini_0172 7.04e-145 436.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_20175_2 1348657.M622_08280 5.96e-64 209.0 2C2F5@1|root,32WND@2|Bacteria,1N9J7@1224|Proteobacteria,2W66E@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_4145_1 118005.AWNK01000007_gene773 1.86e-18 84.7 COG1192@1|root,COG1192@2|Bacteria 2|Bacteria D plasmid maintenance - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_4145_2 1278309.KB907101_gene705 8.6e-226 630.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XIC4@135619|Oceanospirillales 135619|Oceanospirillales JKL Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_4145_3 1278309.KB907101_gene708 9.01e-202 560.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1XHZG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase k141_4145_4 1278309.KB907102_gene241 4.69e-94 277.0 COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,1S48A@1236|Gammaproteobacteria,1XJKK@135619|Oceanospirillales 135619|Oceanospirillales J rRNA methyltransferase - - - - - - - - - - - - SpoU_methylase k141_4145_5 1388763.O165_023130 6.22e-125 370.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1YV8J@136845|Pseudomonas putida group 1236|Gammaproteobacteria P chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_4147_1 420324.KI911970_gene1564 3.81e-115 351.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_6965_1 765912.Thimo_2324 1.76e-66 212.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1WXDV@135613|Chromatiales 135613|Chromatiales K response regulator receiver - - - ko:K13041 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_6965_2 1123366.TH3_07937 8.27e-167 481.0 COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2TVHI@28211|Alphaproteobacteria,2JR2P@204441|Rhodospirillales 204441|Rhodospirillales C Cytochrome D1 heme domain - - - - - - - - - - - - Cytochrom_D1,Cytochrome_CBB3 k141_4148_1 1123399.AQVE01000017_gene3646 2.05e-28 111.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,45ZRJ@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_4148_2 292415.Tbd_0563 2.74e-47 167.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1KSXW@119069|Hydrogenophilales 119069|Hydrogenophilales F 5'-nucleotidase, C-terminal domain - - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C k141_20176_1 1288826.MSNKSG1_01603 1.55e-175 493.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RR7U@1236|Gammaproteobacteria,464ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_20176_2 1288826.MSNKSG1_01598 1.2e-148 425.0 COG0697@1|root,COG0697@2|Bacteria,1Q026@1224|Proteobacteria,1S1PS@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_6967_1 717773.Thicy_1078 5.44e-66 215.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,46067@72273|Thiotrichales 72273|Thiotrichales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_19006_1 1278309.KB907099_gene2564 7.83e-132 399.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_9198_3 1267533.KB906740_gene234 5.28e-25 101.0 COG1234@1|root,COG1234@2|Bacteria 2|Bacteria L tRNA 3'-trailer cleavage - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Lactamase_B,Lactamase_B_2 k141_151_1 1095769.CAHF01000023_gene549 1.7e-05 47.8 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2W8YQ@28216|Betaproteobacteria,476V7@75682|Oxalobacteraceae 28216|Betaproteobacteria T PAS fold - - - - - - - - - - - - GAF_2,HATPase_c,PAS_3,Response_reg k141_151_2 504832.OCAR_7330 6.97e-33 125.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,3JQS5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH k141_3669_1 870187.Thini_2499 4.07e-183 535.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales 72273|Thiotrichales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_7141_1 1499686.BN1079_00161 4.15e-38 137.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria 1236|Gammaproteobacteria N flagellar biosynthetic protein FliR fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_7141_2 717774.Marme_3222 1.81e-23 92.4 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1XMC2@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar biosynthetic protein FliQ fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_12017_1 305900.GV64_06685 1.27e-19 84.7 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XH9C@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_12017_2 396588.Tgr7_2778 9.23e-127 396.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_2241_1 1235457.C404_01490 1.99e-91 271.0 COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,1K4BD@119060|Burkholderiaceae 28216|Betaproteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C k141_14118_1 1278309.KB907099_gene2627 2.49e-52 171.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1S4IN@1236|Gammaproteobacteria,1XJK2@135619|Oceanospirillales 135619|Oceanospirillales O 4Fe-4S single cluster domain nrdG - - - - - - - - - - - Fer4_12,Radical_SAM k141_14118_2 1278309.KB907099_gene2628 0.0 1041.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XHTJ@135619|Oceanospirillales 135619|Oceanospirillales KLT Serine/threonine phosphatases, family 2C, catalytic domain - - - - - - - - - - - - PP2C_2,Pkinase k141_14118_3 1278309.KB907099_gene2629 0.0 904.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,1XHYM@135619|Oceanospirillales 135619|Oceanospirillales P Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_14118_5 1278309.KB907099_gene2630 1.24e-132 379.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1XINH@135619|Oceanospirillales 135619|Oceanospirillales T response regulator - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_14118_6 1278309.KB907099_gene2631 0.0 939.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1XHP6@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_14118_7 1278309.KB907099_gene2632 5.59e-106 317.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1XI0Y@135619|Oceanospirillales 135619|Oceanospirillales P Major Facilitator Superfamily - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_4361_1 367336.OM2255_12270 2.06e-96 285.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2U6ZT@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I ctaG GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_18293_1 1049564.TevJSym_ae00650 1.07e-109 323.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_18293_2 164757.Mjls_4328 6.7e-40 140.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,23999@1762|Mycobacteriaceae 201174|Actinobacteria K Rhodanese-like domain - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese k141_14833_1 1249627.D779_0214 3.29e-41 146.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_14833_2 1469245.JFBG01000061_gene2310 1.24e-12 63.5 COG3242@1|root,COG3242@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2065) yjeT - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_14833_3 1095769.CAHF01000011_gene2391 9.15e-10 60.1 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,473D3@75682|Oxalobacteraceae 28216|Betaproteobacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_1564_2 1278309.KB907100_gene1954 1.86e-166 471.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,1XPDF@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c - - 1.17.2.1 ko:K18030 ko00760,ko01120,map00760,map01120 M00622 R09473 RC00589 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_C k141_1564_3 1278309.KB907100_gene1955 4.69e-90 268.0 COG3909@1|root,COG3909@2|Bacteria,1RHCJ@1224|Proteobacteria,1SIC5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C' - - - - - - - - - - - - Cytochrom_C_2 k141_1564_4 234831.PSM_A1410 7.58e-157 453.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,2Q017@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K Peptidase_C39 like family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_1564_5 1056820.KB900641_gene566 1.23e-105 319.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,2PPJH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria HJ RimK-like ATPgrasp N-terminal domain - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k141_9896_1 987059.RBXJA2T_14051 3.87e-63 203.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VMPX@28216|Betaproteobacteria,1KIXZ@119065|unclassified Burkholderiales 28216|Betaproteobacteria H Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR1 - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_9896_2 697282.Mettu_2769 3.22e-07 51.2 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1S7F5@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis signal transduction protein cheW3 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_10665_2 596154.Alide2_4603 4.52e-53 180.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,4ABI2@80864|Comamonadaceae 28216|Betaproteobacteria T protein phosphatase 2C domain protein pppL - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 k141_10665_3 1304883.KI912532_gene1687 1.78e-35 130.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA k141_20425_1 296591.Bpro_5550 3.03e-106 317.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,4A9SH@80864|Comamonadaceae 28216|Betaproteobacteria C NADH flavin oxidoreductase NADH oxidase - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_16210_1 1123393.KB891316_gene1208 3.98e-22 93.6 COG1249@1|root,COG1249@2|Bacteria,1RGSP@1224|Proteobacteria,2VYSB@28216|Betaproteobacteria 28216|Betaproteobacteria C Alkylmercury lyase merB - 4.99.1.2 ko:K00221 - - - - ko00000,ko01000 - - - HTH_15,MerB k141_5804_2 1288826.MSNKSG1_00973 3.2e-209 579.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,464E1@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the RimK family rimK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_5804_3 1288826.MSNKSG1_00978 9.42e-257 704.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_5804_4 1288826.MSNKSG1_00983 1.69e-100 291.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,467NM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0047 yjbQ - - - - - - - - - - - UPF0047 k141_5804_5 1288826.MSNKSG1_00988 1.02e-233 643.0 COG2358@1|root,COG2358@2|Bacteria,1N3YB@1224|Proteobacteria,1RVT1@1236|Gammaproteobacteria,466E4@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, periplasmic component - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_5804_6 1288826.MSNKSG1_00993 0.0 1338.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,465DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, fused permease components - - - - - - - - - - - - DctM k141_5804_7 1288826.MSNKSG1_00998 0.0 1106.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,464DB@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system dctB - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 k141_5804_8 1288826.MSNKSG1_01003 4.42e-34 127.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,463YQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains dctD - - ko:K08476,ko:K10126 ko02020,map02020 M00503,M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_19025_1 1278309.KB907099_gene2993 6.64e-146 421.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XICB@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_12040_1 765913.ThidrDRAFT_0212 5.9e-114 346.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1WX77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_168_1 521719.ATXQ01000011_gene154 1.6e-81 249.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1YDJU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Protein of unknown function DUF47 UF78_21250 - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_168_2 1177179.A11A3_03769 1.81e-83 259.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XIG9@135619|Oceanospirillales 135619|Oceanospirillales P phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_20426_1 1278309.KB907106_gene1279 1.56e-105 318.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XH3M@135619|Oceanospirillales 135619|Oceanospirillales H enzyme of heme biosynthesis hemX - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX k141_2253_1 1238450.VIBNISOn1_1760016 1.31e-62 194.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,1XYPG@135623|Vibrionales 135623|Vibrionales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_19704_1 314232.SKA53_12668 4.06e-77 246.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2TRMX@28211|Alphaproteobacteria,2P8EZ@245186|Loktanella 28211|Alphaproteobacteria S Peptidase M16 inactive domain MA20_05660 - - ko:K07263,ko:K07623 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_10666_1 1232683.ADIMK_3944 2.48e-105 339.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_8562_1 1163617.SCD_n01211 1.49e-111 331.0 COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria 28216|Betaproteobacteria S DMSO reductase anchor subunit (DmsC) dmsC - - ko:K21309 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 - - - DmsC k141_14136_1 1278309.KB907100_gene2301 3.76e-165 464.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1XHC3@135619|Oceanospirillales 135619|Oceanospirillales D Chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_14136_2 1278309.KB907100_gene2300 4.73e-129 369.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1XJ8Z@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_14136_3 1278309.KB907100_gene2299 0.0 1183.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1XHS4@135619|Oceanospirillales 135619|Oceanospirillales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_14136_4 1134474.O59_003508 8.04e-58 185.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1FIA5@10|Cellvibrio 1236|Gammaproteobacteria O Thioredoxin trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_14136_5 1278309.KB907100_gene2297 1.99e-122 360.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales 135619|Oceanospirillales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_881_1 1278309.KB907100_gene1932 4.85e-45 147.0 28NXJ@1|root,2ZBV4@2|Bacteria,1RD2V@1224|Proteobacteria,1S3XU@1236|Gammaproteobacteria,1XKYM@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0325 family - - - - - - - - - - - - DUF3461 k141_881_2 1278309.KB907100_gene1933 4.84e-167 469.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1XHAN@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N k141_881_3 1278309.KB907100_gene1934 1.41e-172 483.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1XHF8@135619|Oceanospirillales 135619|Oceanospirillales E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_881_4 1278309.KB907100_gene1935 1.11e-232 645.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1XH4T@135619|Oceanospirillales 135619|Oceanospirillales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_881_6 1278309.KB907100_gene1937 5.2e-83 251.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1XK1E@135619|Oceanospirillales 135619|Oceanospirillales O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_18307_1 1042377.AFPJ01000023_gene656 0.0 1134.0 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF11,OmpA k141_18307_3 317025.Tcr_0818 1.82e-110 317.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,46002@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k141_18307_4 1122214.AQWH01000006_gene2495 4.39e-08 54.7 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,2PJM0@255475|Aurantimonadaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa k141_3679_1 1288826.MSNKSG1_10973 0.0 1149.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_3679_2 1288826.MSNKSG1_10968 0.0 1087.0 COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria,46653@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitrate reductase beta subunit narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Fer4_11,Nitr_red_bet_C k141_3679_3 1288826.MSNKSG1_10963 3.69e-135 385.0 COG2180@1|root,COG2180@2|Bacteria,1MY4E@1224|Proteobacteria,1RQ23@1236|Gammaproteobacteria,46590@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitrate reductase, delta subunit narJ GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,ic_1306.c1687 Nitrate_red_del k141_21778_1 1278309.KB907100_gene1819 1.19e-23 94.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1XJD0@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_21778_2 1278309.KB907100_gene1820 6.04e-169 473.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1XHTY@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_21778_3 1278309.KB907100_gene1821 5.37e-173 486.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1XINF@135619|Oceanospirillales 135619|Oceanospirillales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_21778_4 1278309.KB907100_gene1822 2.88e-166 466.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1XHTB@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_21778_5 743720.Psefu_3433 3.07e-64 203.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1YUVS@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_16917_1 998674.ATTE01000001_gene364 1.35e-168 489.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,460E6@72273|Thiotrichales 72273|Thiotrichales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_5806_1 396588.Tgr7_2800 5.6e-44 158.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1X2PU@135613|Chromatiales 135613|Chromatiales EGP Drug resistance transporter Bcr CflA subfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_12041_1 458817.Shal_3376 1.17e-24 104.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,2Q97D@267890|Shewanellaceae 1236|Gammaproteobacteria CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_12041_2 237368.SCABRO_01929 2.84e-40 146.0 COG0025@1|root,COG0025@2|Bacteria,2IZBZ@203682|Planctomycetes 203682|Planctomycetes P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_8563_1 384765.SIAM614_07753 6.94e-55 187.0 COG0508@1|root,COG0508@2|Bacteria,1R6BB@1224|Proteobacteria,2U1GZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Biotin-requiring enzyme - - 2.3.1.12,2.3.1.61 ko:K00627,ko:K00658 ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00307 R00209,R02569,R02570,R02571,R08549 RC00004,RC02727,RC02742,RC02833,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl k141_10667_1 985054.JQEZ01000003_gene1074 4.78e-52 186.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4NAJG@97050|Ruegeria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_18308_2 1278309.KB907109_gene3301 1.2e-45 152.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1XK24@135619|Oceanospirillales 135619|Oceanospirillales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_17616_2 1215092.PA6_024_00140 2.47e-16 74.7 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RPZ8@1236|Gammaproteobacteria,1YGAB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E RadC-like JAB domain - - - ko:K03630 - - - - ko00000 - - - RadC k141_5043_1 269796.Rru_A3313 6.99e-38 137.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_20427_1 932213.SPM24T3_12334 4.21e-79 243.0 COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,401GR@613|Serratia 1236|Gammaproteobacteria L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair mutH GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - ko:K03573 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutH k141_5807_1 388399.SSE37_24494 8.93e-113 342.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_2406_2 1123368.AUIS01000007_gene2739 5.77e-52 182.0 COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,2NBVW@225057|Acidithiobacillales 225057|Acidithiobacillales C e3 binding domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim k141_12181_1 388401.RB2150_08573 3.45e-06 47.8 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2TS23@28211|Alphaproteobacteria,3ZI32@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities urtE - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k141_12181_2 388401.RB2150_08568 5.95e-63 199.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2TQVJ@28211|Alphaproteobacteria,3ZI8G@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria P transport system, ATPase component urtD - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_14241_2 545276.KB898727_gene324 9.88e-58 188.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1WY11@135613|Chromatiales 135613|Chromatiales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_14241_3 477641.MODMU_5556 2.18e-15 79.0 COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4ESRD@85013|Frankiales 201174|Actinobacteria H PFAM Phosphomethylpyrimidine kinase type-1 thiD - 2.5.1.3,2.7.1.49,2.7.4.7 ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R04509,R10712 RC00002,RC00017,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TENA_THI-4,TMP-TENI k141_17773_1 207954.MED92_13843 1.03e-98 293.0 COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,1RY60@1236|Gammaproteobacteria,1XHMB@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the HisA HisF family - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_17773_2 28229.ND2E_4177 2.21e-51 193.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_17773_3 243160.BMA1686 2.78e-62 197.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,1KFI3@119060|Burkholderiaceae 28216|Betaproteobacteria S Transferase hexapeptide repeat yrdA - - - - - - - - - - - Hexapep k141_17773_4 1278309.KB907099_gene2503 3.01e-14 74.7 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XIJI@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase M23 - - - ko:K19304 - - - - ko00000,ko01000,ko01002,ko01011 - - - OapA,Peptidase_M23 k141_13547_2 330214.NIDE2816 5.69e-05 50.1 COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,3J0NC@40117|Nitrospirae 40117|Nitrospirae T HDOD domain - - - - - - - - - - - - HDOD k141_12891_1 396588.Tgr7_3076 1.18e-103 307.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1WWMU@135613|Chromatiales 135613|Chromatiales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_19180_1 225937.HP15_1434 3.36e-40 136.0 28VZK@1|root,2ZI0S@2|Bacteria,1P618@1224|Proteobacteria,1STA9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19180_3 443152.MDG893_03040 1.44e-56 177.0 COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,1SCJR@1236|Gammaproteobacteria,46C1B@72275|Alteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 k141_1742_1 1288826.MSNKSG1_12092 4.65e-74 227.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,4659G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_1742_2 1288826.MSNKSG1_12087 1.21e-84 251.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,468EP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_1742_3 1288826.MSNKSG1_12082 1.54e-32 114.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,468CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03116,ko:K03425 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_1742_4 1288826.MSNKSG1_12077 8.24e-45 146.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,467UR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0140 Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_328_1 1232683.ADIMK_0722 7.18e-229 651.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,464G0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_3803_1 998088.B565_0148 3.68e-99 312.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1Y3WP@135624|Aeromonadales 135624|Aeromonadales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C k141_5905_1 1279019.ARQK01000041_gene510 2.21e-149 432.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1WWHU@135613|Chromatiales 135613|Chromatiales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_21949_1 626887.J057_23060 1.33e-271 763.0 COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,1RMGX@1236|Gammaproteobacteria,465E9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2943 Membrane glycosyltransferase mdoH GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 - ko:K03669 - - - - ko00000,ko01000,ko01003,ko02000 4.D.3.1.1 GT2 - Glyco_trans_2_3,Glycos_transf_2 k141_21949_2 1288826.MSNKSG1_07023 1.04e-304 835.0 COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,4654Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) mdoD GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006109,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009889,GO:0009987,GO:0010556,GO:0010675,GO:0010962,GO:0016051,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031326,GO:0031975,GO:0032881,GO:0032885,GO:0032950,GO:0032951,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0043255,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050789,GO:0050794,GO:0051273,GO:0051274,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901576,GO:2000112 - ko:K03670 - - - - ko00000 - - - MdoG k141_10804_1 351348.Maqu_2590 3.57e-69 231.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,4661Y@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_10804_2 1288826.MSNKSG1_08618 4.96e-87 256.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,4689S@72275|Alteromonadaceae 1236|Gammaproteobacteria N flagellar protein FliS fliS - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_11483_1 1485544.JQKP01000017_gene610 5.79e-56 186.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales 28216|Betaproteobacteria I Squalene/phytoene synthase hpnC - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_11483_2 396588.Tgr7_1524 4.25e-12 64.7 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RNRI@1236|Gammaproteobacteria,1WYA5@135613|Chromatiales 135613|Chromatiales I Squalene phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_1012_1 1278309.KB907101_gene761 0.0 1293.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XI88@135619|Oceanospirillales 135619|Oceanospirillales C FAD-linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_15655_1 1278309.KB907102_gene165 4.05e-204 590.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1XH65@135619|Oceanospirillales 135619|Oceanospirillales L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,Flavi_DEAD,HA2,Helicase_C,HrpB_C k141_15655_2 1278309.KB907102_gene163 6.95e-74 223.0 COG2824@1|root,COG2824@2|Bacteria,1N1JG@1224|Proteobacteria,1S98R@1236|Gammaproteobacteria,1XKGA@135619|Oceanospirillales 135619|Oceanospirillales P Alkylphosphonate utilization operon protein PhnA - - - - - - - - - - - - - k141_15655_3 207954.MED92_06383 5.61e-242 674.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XIPI@135619|Oceanospirillales 135619|Oceanospirillales E alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_5173_2 1185766.DL1_17140 3.27e-79 238.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,2XMM0@285107|Thioclava 28211|Alphaproteobacteria J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB k141_1743_1 926559.JoomaDRAFT_3515 5.03e-13 73.9 COG2911@1|root,COG3209@1|root,COG3210@1|root,COG4677@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4677@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia 976|Bacteroidetes M SprB repeat - - - - - - - - - - - - CHU_C,SprB k141_9336_1 349521.HCH_04909 1.69e-56 186.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XIE3@135619|Oceanospirillales 135619|Oceanospirillales S Permease perM - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_9336_2 765914.ThisiDRAFT_2090 4.71e-69 222.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales 135613|Chromatiales T SMART Nucleotide binding protein, PINc - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_15656_1 1163408.UU9_15260 1.61e-53 184.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1X3CI@135614|Xanthomonadales 135614|Xanthomonadales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_330_1 452471.Aasi_0475 5.2e-08 56.2 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_330_2 1121904.ARBP01000002_gene6988 2.7e-12 68.6 COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,47M4P@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 4 - - - - - - - - - - - - Glycos_transf_4 k141_3804_1 697282.Mettu_0073 9.79e-90 271.0 COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,1XEUN@135618|Methylococcales 135618|Methylococcales H Thiamine biosynthesis protein (ThiI) - - - - - - - - - - - - ThiI k141_7299_1 571166.KI421509_gene2161 0.000154 43.9 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mechanosensitive ion channel MA20_40450 - - - - - - - - - - - MS_channel k141_7299_2 754476.Q7A_877 2.58e-184 529.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales 72273|Thiotrichales L Exonuclease C-terminal sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_21273_1 1278309.KB907104_gene852 9.8e-222 621.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RRSQ@1236|Gammaproteobacteria,1XIIN@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_21273_2 1278309.KB907104_gene853 5.77e-66 201.0 COG0251@1|root,COG0251@2|Bacteria,1N165@1224|Proteobacteria,1S43G@1236|Gammaproteobacteria,1XRDD@135619|Oceanospirillales 135619|Oceanospirillales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_17775_1 247633.GP2143_03114 4.4e-44 155.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1J50G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_17775_2 1236541.BALL01000032_gene3424 4.53e-67 207.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,2QBKF@267890|Shewanellaceae 1236|Gammaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3360 YgbB k141_6550_1 795797.C497_06924 8.98e-62 198.0 297W1@1|root,2N5NZ@2157|Archaea,2XVHS@28890|Euryarchaeota,23UMZ@183963|Halobacteria 183963|Halobacteria S Domain of unknown function (DUF4396) - - - - - - - - - - - - DUF4396 k141_18429_1 351348.Maqu_0053 4.92e-105 305.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,466EI@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - - - - - - - - - - Hexapep k141_18429_2 1288826.MSNKSG1_14877 1.41e-101 294.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,468FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family hspA - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_18429_3 1288826.MSNKSG1_14872 1.32e-66 202.0 2D7C6@1|root,32TNS@2|Bacteria,1MZUP@1224|Proteobacteria,1SCEG@1236|Gammaproteobacteria,468C9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aminopeptidase - - - - - - - - - - - - - k141_18429_4 1288826.MSNKSG1_14867 4.45e-188 523.0 COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,46CJH@72275|Alteromonadaceae 1236|Gammaproteobacteria N Membrane MotB of proton-channel complex MotA/MotB - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_18429_5 1288826.MSNKSG1_14862 1.03e-167 470.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,4658K@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1291 Flagellar motor component - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_1744_1 1121445.ATUZ01000011_gene322 2.45e-49 174.0 COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2M8TP@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - Peptidase_M99,Peptidase_M99_C k141_12183_1 1232683.ADIMK_2699 1.25e-79 261.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,468ZD@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S8 family - - - - - - - - - - - - PKD,P_proprotein,Peptidase_S8 k141_9337_1 1121479.AUBS01000029_gene83 9.77e-27 102.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_39715 - - - - - - - - - - - DUF1178 k141_9337_2 349102.Rsph17025_0636 7.93e-49 167.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,1FARX@1060|Rhodobacter 28211|Alphaproteobacteria E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_5907_1 270374.MELB17_03425 1.59e-19 85.9 2EKFG@1|root,33E5M@2|Bacteria,1NJ6W@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4402) - - - - - - - - - - - - DUF4402 k141_13548_1 1288826.MSNKSG1_07998 4.39e-151 427.0 COG0300@1|root,COG0300@2|Bacteria,1R9VQ@1224|Proteobacteria,1S1WG@1236|Gammaproteobacteria,46AYC@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_13548_2 1288826.MSNKSG1_08003 3.38e-109 320.0 COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,1S295@1236|Gammaproteobacteria,466K7@72275|Alteromonadaceae 1236|Gammaproteobacteria GK ROK family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_11484_1 593105.S7A_15515 1.11e-47 162.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,3W099@53335|Pantoea 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N k141_7300_1 1122132.AQYH01000001_gene888 1.19e-47 173.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria,4B7P2@82115|Rhizobiaceae 28211|Alphaproteobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_19183_1 882378.RBRH_01375 7.67e-86 273.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1K219@119060|Burkholderiaceae 28216|Betaproteobacteria S abc transporter uup - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_8680_1 395493.BegalDRAFT_1870 2.57e-72 239.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,45ZTT@72273|Thiotrichales 72273|Thiotrichales T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA k141_8680_2 243924.LT42_17500 1.6e-88 275.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains pilR - - ko:K02481,ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_17045_1 857087.Metme_4265 3.47e-54 187.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XDRF@135618|Methylococcales 135618|Methylococcales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom k141_17045_2 511062.GU3_00035 1.46e-36 130.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1Y4CX@135624|Aeromonadales 135624|Aeromonadales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_5176_1 28229.ND2E_0777 2.43e-79 243.0 COG0500@1|root,COG2226@2|Bacteria,1PDVU@1224|Proteobacteria,1RXQY@1236|Gammaproteobacteria,2Q853@267889|Colwelliaceae 1236|Gammaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - - k141_17776_1 1168067.JAGP01000001_gene402 1.05e-135 395.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,45ZP3@72273|Thiotrichales 72273|Thiotrichales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_1014_2 981384.AEYW01000006_gene2837 1.64e-26 108.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,4NACX@97050|Ruegeria 28211|Alphaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_16333_1 314278.NB231_12691 4.22e-92 293.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_1033_1 1168067.JAGP01000001_gene2097 3.39e-106 324.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,4604K@72273|Thiotrichales 72273|Thiotrichales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_18446_1 1278309.KB907101_gene279 1.72e-43 162.0 COG1361@1|root,COG2304@1|root,COG2931@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1XK3E@135619|Oceanospirillales 135619|Oceanospirillales Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - VWA_2 k141_12210_1 329726.AM1_5416 2.01e-35 126.0 COG1943@1|root,COG1943@2|Bacteria,1G9TK@1117|Cyanobacteria 1117|Cyanobacteria L PFAM Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_8077_1 765912.Thimo_2101 2.13e-44 164.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1WXN2@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) - - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_12904_1 63737.Npun_F5226 7.31e-54 184.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G3BJ@1117|Cyanobacteria,1HP35@1161|Nostocales 1117|Cyanobacteria L methylated-DNA- protein -cysteine S-methyltransferase - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N k141_12904_2 631362.Thi970DRAFT_04048 1.75e-57 190.0 COG0647@1|root,COG0647@2|Bacteria,1QHTN@1224|Proteobacteria,1S8KM@1236|Gammaproteobacteria,1WZUP@135613|Chromatiales 135613|Chromatiales G PFAM Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like k141_4548_1 580332.Slit_1585 4.79e-21 89.4 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VMPX@28216|Betaproteobacteria,44W6Z@713636|Nitrosomonadales 28216|Betaproteobacteria H Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR1 - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_4548_2 582744.Msip34_2703 1.79e-47 159.0 COG1871@1|root,COG1871@2|Bacteria,1RI55@1224|Proteobacteria,2VUAC@28216|Betaproteobacteria,2KNVI@206350|Nitrosomonadales 206350|Nitrosomonadales NT CheD chemotactic sensory transduction - - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_19205_1 1127673.GLIP_0124 1.21e-106 323.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,4651X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DNA photolyase family phrB GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_19205_2 1123514.KB905899_gene1174 6.4e-67 207.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,460XE@72273|Thiotrichales 72273|Thiotrichales P Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide cynS - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase k141_19205_3 1190603.AJYD01000060_gene1463 3.17e-28 116.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RX16@1236|Gammaproteobacteria,1XX30@135623|Vibrionales 135623|Vibrionales T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9 k141_16463_1 999141.GME_03367 6.5e-40 133.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1XKET@135619|Oceanospirillales 135619|Oceanospirillales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq k141_12348_2 1168067.JAGP01000001_gene221 1.27e-39 137.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,46063@72273|Thiotrichales 72273|Thiotrichales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_15068_1 742726.HMPREF9448_01782 1.85e-14 73.2 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,22W21@171551|Porphyromonadaceae 976|Bacteroidetes F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_7439_1 396588.Tgr7_0516 9.32e-125 370.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales 135613|Chromatiales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_7439_2 754477.Q7C_1179 4.6e-38 129.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales 72273|Thiotrichales H Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_10938_1 1278309.KB907101_gene385 9.39e-158 458.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XIQU@135619|Oceanospirillales 135619|Oceanospirillales T Chemotaxis sensory transducer family protein - - - - - - - - - - - - GAF,GAF_2,HD,HD_5 k141_10938_2 1278309.KB907101_gene383 2.42e-95 283.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,1S453@1236|Gammaproteobacteria,1XKBG@135619|Oceanospirillales 135619|Oceanospirillales S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 k141_13731_1 95619.PM1_0211690 1.34e-63 206.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 ko:K01903,ko:K14067 ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00346,M00374,M00620 R00405,R01256,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_6680_2 1278309.KB907107_gene1720 3.56e-59 186.0 COG2882@1|root,COG2882@2|Bacteria,1RHFM@1224|Proteobacteria,1S76M@1236|Gammaproteobacteria,1XMAE@135619|Oceanospirillales 135619|Oceanospirillales NOU Flagellar FliJ protein fliJ - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_11602_1 1168065.DOK_01639 1.57e-66 235.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1J5C9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_9446_1 1278309.KB907105_gene1493 9.62e-71 213.0 COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1XKJ2@135619|Oceanospirillales 135619|Oceanospirillales M 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP k141_19944_1 1198232.CYCME_1326 8.49e-21 94.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,4620U@72273|Thiotrichales 72273|Thiotrichales MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_19944_2 203122.Sde_1930 4.46e-27 111.0 COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,464X2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CusF_Ec,HlyD_D23,HlyD_D4 k141_13055_1 1278309.KB907100_gene1802 2.2e-155 442.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XJFS@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD - 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_13055_2 1278309.KB907100_gene1803 4.51e-53 168.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1XM4X@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_13055_3 1278309.KB907100_gene1804 2.47e-290 795.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1XHYF@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_5994_1 472759.Nhal_3888 1.1e-31 117.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1WYAC@135613|Chromatiales 135613|Chromatiales NU pilus assembly protein PilP - - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP k141_5994_2 519989.ECTPHS_06482 1.9e-94 303.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_21405_1 519989.ECTPHS_01629 8.44e-83 260.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WXMK@135613|Chromatiales 135613|Chromatiales S Polyphosphate AMP phosphotransferase - - - - - - - - - - - - PPK2 k141_21405_3 1116472.MGMO_171c00230 3.08e-73 229.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,1XE6X@135618|Methylococcales 135618|Methylococcales S aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_2525_1 1255043.TVNIR_3050 5.69e-61 193.0 COG1416@1|root,COG1416@2|Bacteria,1RHW0@1224|Proteobacteria 1224|Proteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_17913_1 261292.Nit79A3_3207 4.01e-08 54.7 COG3767@1|root,COG3767@2|Bacteria,1PW5I@1224|Proteobacteria,2WBQU@28216|Betaproteobacteria,373MA@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_19319_1 1278309.KB907101_gene402 0.0 1748.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XH7V@135619|Oceanospirillales 135619|Oceanospirillales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_12349_1 1121878.AUGL01000018_gene18 1.22e-26 114.0 29W90@1|root,30HUD@2|Bacteria,1R92S@1224|Proteobacteria,1S1CJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3285_1 1177154.Y5S_01704 1.14e-98 327.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_1859_1 743720.Psefu_0615 6.82e-14 67.4 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1YYP2@136845|Pseudomonas putida group 1236|Gammaproteobacteria S PFAM conserved - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_1859_2 1123393.KB891316_gene1770 1.19e-49 164.0 COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,1KRYX@119069|Hydrogenophilales 119069|Hydrogenophilales CO SCO1/SenC - - - - - - - - - - - - - k141_1193_1 351348.Maqu_3382 3.33e-56 193.0 COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,1S320@1236|Gammaproteobacteria,467JW@72275|Alteromonadaceae 1236|Gammaproteobacteria V restriction modification system DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k141_482_1 1168067.JAGP01000001_gene1364 8.39e-16 77.4 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,45ZRD@72273|Thiotrichales 72273|Thiotrichales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_482_2 748247.AZKH_0185 5.43e-45 153.0 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria,2KZ3G@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_6681_1 357804.Ping_1180 4.12e-14 78.2 COG1835@1|root,COG1835@2|Bacteria,1NCI4@1224|Proteobacteria,1SJ6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k141_13732_1 666509.RCA23_c29360 5.83e-37 133.0 COG2207@1|root,COG2207@2|Bacteria,1NDY5@1224|Proteobacteria,2UNPD@28211|Alphaproteobacteria 28211|Alphaproteobacteria K araC family - - - - - - - - - - - - AraC_binding,HTH_18 k141_13732_2 349521.HCH_01298 1.38e-21 97.4 COG0246@1|root,COG1028@1|root,COG0246@2|Bacteria,COG1028@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,1XR46@135619|Oceanospirillales 135619|Oceanospirillales C Mannitol dehydrogenase C-terminal domain - - 1.1.1.11 ko:K00007 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00868,R05604 RC00085,RC00102 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_16466_1 225937.HP15_352 4.66e-85 262.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,464RI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k141_9447_1 1123487.KB892866_gene1602 5.35e-17 89.4 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales 206389|Rhodocyclales T Diguanylate cyclase - - - - - - - - - - - - CBS,CZB,EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_10940_1 396588.Tgr7_0497 7.32e-84 261.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1WXYV@135613|Chromatiales 135613|Chromatiales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_19333_1 1380380.JIAX01000006_gene999 1.64e-44 154.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TTZY@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Transglutaminase MA20_32430 - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_19333_2 398580.Dshi_3243 3.51e-67 214.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2TQUM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria MA20_32425 - - - - - - - - - - - Alpha-E k141_3311_1 981336.F944_02787 1.25e-61 209.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3NIKD@468|Moraxellaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_11631_1 4572.TRIUR3_00337-P1 3.34e-75 226.0 COG0049@1|root,KOG3291@2759|Eukaryota,37YX8@33090|Viridiplantae,3GNS6@35493|Streptophyta,3KTYP@4447|Liliopsida,3IAPX@38820|Poales 35493|Streptophyta J ribosomal protein S7 - - - - - - - - - - - - Ribosomal_S7 k141_10955_1 1366050.N234_10615 2.14e-87 263.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2VQ1J@28216|Betaproteobacteria,1K50F@119060|Burkholderiaceae 28216|Betaproteobacteria C NADH dehydrogenase NAD(P)H nitroreductase rutE - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k141_17192_1 1122201.AUAZ01000006_gene3875 2.46e-54 179.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,464JS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849 Porphobil_deam,Porphobil_deamC k141_6693_1 296587.XP_002503525.1 2.81e-06 53.1 COG0484@1|root,KOG0714@2759|Eukaryota,37QCW@33090|Viridiplantae,34HEK@3041|Chlorophyta 3041|Chlorophyta O DnaJ molecular chaperone homology domain - - - ko:K09510,ko:K09530 ko04141,map04141 - - - ko00000,ko00001,ko03110,ko04131 - - - Armet,DnaJ,Thioredoxin k141_3929_1 1121434.AULY01000007_gene1572 1.55e-94 293.0 COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2M8TP@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - Peptidase_M99,Peptidase_M99_C k141_3312_1 1278309.KB907101_gene404 3.8e-33 120.0 COG1180@1|root,COG1180@2|Bacteria,1RA4Z@1224|Proteobacteria,1S34Q@1236|Gammaproteobacteria,1XRSI@135619|Oceanospirillales 135619|Oceanospirillales O 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_14,Radical_SAM k141_16496_1 1121939.L861_00180 1.23e-33 127.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria 1236|Gammaproteobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 k141_16496_2 1123393.KB891331_gene2898 1.18e-15 73.9 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,2VTYD@28216|Betaproteobacteria 28216|Betaproteobacteria I PFAM phosphoesterase, PA-phosphatase related - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_6010_2 1122194.AUHU01000003_gene2284 2.31e-104 345.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,YfiO k141_1882_1 1111728.ATYS01000009_gene503 2.77e-88 278.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 iSFV_1184.SFV_3438 Glyco_transf_5,Glycos_transf_1 k141_15851_1 349163.Acry_1797 2.62e-29 115.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria,2JQ52@204441|Rhodospirillales 204441|Rhodospirillales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_15851_2 314345.SPV1_01852 1.92e-74 235.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria 1224|Proteobacteria V Abc-type multidrug transport system, permease component ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_2551_2 1347086.CCBA010000003_gene3822 9.87e-23 106.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - 1.16.3.3,1.7.2.1 ko:K00368,ko:K07233,ko:K22349 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_8788_1 1122599.AUGR01000015_gene2666 5.75e-07 50.1 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,1S3T2@1236|Gammaproteobacteria,1XKV0@135619|Oceanospirillales 135619|Oceanospirillales S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 k141_8788_2 909613.UO65_2826 0.000479 47.0 COG0204@1|root,COG0204@2|Bacteria,2GJBQ@201174|Actinobacteria,4E0RN@85010|Pseudonocardiales 201174|Actinobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_16497_1 391615.ABSJ01000026_gene112 1.73e-41 155.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1J6GE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_5384_2 857087.Metme_2685 4.28e-71 239.0 COG0004@1|root,COG5000@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_9 k141_15089_1 1288826.MSNKSG1_15097 3.34e-185 523.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,469I2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_15089_2 1288826.MSNKSG1_15102 4.27e-177 494.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,1RQDF@1236|Gammaproteobacteria,46CHE@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) bdhA - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k141_15089_3 1288826.MSNKSG1_15107 0.0 1085.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_20700_2 323261.Noc_2656 3.35e-35 137.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales 135613|Chromatiales S Protein of unknown function - - - - - - - - - - - - AsmA_2,DUF3971 k141_15852_2 1288826.MSNKSG1_11033 7.46e-66 216.0 COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg,dCache_1 k141_7467_2 880072.Desac_1764 7.83e-05 50.4 COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42U66@68525|delta/epsilon subdivisions,2X374@28221|Deltaproteobacteria,2MS8Z@213462|Syntrophobacterales 28221|Deltaproteobacteria T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_14359_1 661478.OP10G_1122 5.51e-75 252.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,cNMP_binding k141_4694_1 526218.Sterm_3096 0.000249 51.2 COG0438@1|root,COG0438@2|Bacteria,37C8C@32066|Fusobacteria 2|Bacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Alg14,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 k141_4694_2 565045.NOR51B_761 0.000666 44.3 COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,1RRAJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane protein involved in the export of O-antigen and teichoic acid wzx - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C k141_9467_1 1278309.KB907110_gene3213 3.17e-120 349.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XHGU@135619|Oceanospirillales 135619|Oceanospirillales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_9467_2 1278309.KB907110_gene3212 6.5e-136 388.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1XKF7@135619|Oceanospirillales 135619|Oceanospirillales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_9467_3 1278309.KB907110_gene3211 2.33e-164 462.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XHGB@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_21421_1 765911.Thivi_1248 4.13e-89 270.0 COG1943@1|root,COG1943@2|Bacteria,1R75U@1224|Proteobacteria,1S1SP@1236|Gammaproteobacteria,1WXZQ@135613|Chromatiales 135613|Chromatiales L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_497_2 1288826.MSNKSG1_07463 7.2e-96 280.0 2CU4K@1|root,32SUN@2|Bacteria,1N070@1224|Proteobacteria,1S979@1236|Gammaproteobacteria,46862@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_497_3 1288826.MSNKSG1_07468 3.5e-193 538.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,464V0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M48B family htpX GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_497_4 1288826.MSNKSG1_07473 3.74e-236 654.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,465GC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_497_5 1288826.MSNKSG1_07478 2.01e-303 828.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,464SM@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C,RhlB k141_497_6 1288826.MSNKSG1_07483 5.15e-140 395.0 COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,4678B@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yfcM GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 - ko:K09906 - - - - ko00000,ko01000,ko03012 - - - EpmC k141_497_7 1288826.MSNKSG1_07488 0.0 1119.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,464UD@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin,Thioredoxin_7 k141_17194_1 1288494.EBAPG3_1430 4.52e-58 187.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,3720E@32003|Nitrosomonadales 28216|Betaproteobacteria O Ribosomal RNA adenine dimethylase pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_8789_1 63737.Npun_R2269 1.05e-13 73.9 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,HAMP,PAS_3,Zn_Tnp_IS1595,dCache_1 k141_22248_3 1049564.TevJSym_ai00800 2.16e-42 149.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1J5SW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG0500 SAM-dependent methyltransferases rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_1376_1 519989.ECTPHS_01379 3.63e-78 246.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_21571_1 319003.Bra1253DRAFT_08478 5.91e-07 50.4 COG0596@1|root,COG0596@2|Bacteria,1R9VJ@1224|Proteobacteria 1224|Proteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_21571_3 1163617.SCD_n02577 4.58e-51 171.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria 28216|Betaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_18769_2 472759.Nhal_1712 1.32e-84 266.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales 1236|Gammaproteobacteria F PFAM glycosyl transferase family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_16005_2 1212548.B381_01450 1.59e-45 150.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1Z2QK@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_16005_3 519989.ECTPHS_07257 4.31e-46 157.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_2003_1 765911.Thivi_0418 8e-47 172.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXU3@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_13236_1 1109445.AGSX01000196_gene559 2.22e-16 77.8 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1Z1AN@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG2059 Chromate transport protein ChrA chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_13236_2 1122201.AUAZ01000023_gene3004 1.44e-113 335.0 COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,1S05U@1236|Gammaproteobacteria,469UV@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_11129_1 700598.Niako_1126 0.000869 44.7 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator frzZ - - - - - - - - - - - Response_reg k141_637_1 196367.JNFG01000020_gene4805 8.05e-159 458.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1JZV1@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.96 ko:K16871 ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120 M00027 R10178 RC00008,RC00062 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_3 k141_10419_1 1366046.HIMB11_00490 3.99e-64 212.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TU4G@28211|Alphaproteobacteria 28211|Alphaproteobacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N k141_13919_2 349124.Hhal_1585 3.38e-79 238.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1WYRV@135613|Chromatiales 135613|Chromatiales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_13919_3 395493.BegalDRAFT_2761 4.43e-62 201.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,4617B@72273|Thiotrichales 72273|Thiotrichales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_2703_1 246200.SPO3467 1.21e-98 294.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,4NA3I@97050|Ruegeria 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component potH GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11075 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 k141_2703_2 670307.HYPDE_31503 1.19e-09 57.8 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,3N7NP@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component potI GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11074 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 k141_16006_1 1168067.JAGP01000001_gene437 8.54e-89 269.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,45ZWU@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM KamA family protein epmB - - ko:K19810 - - - - ko00000,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM k141_9639_1 1121920.AUAU01000001_gene2265 3.46e-72 253.0 COG5001@1|root,COG5001@2|Bacteria,3Y32A@57723|Acidobacteria 57723|Acidobacteria T PFAM EAL domain - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS,Response_reg k141_13237_1 1121937.AUHJ01000008_gene2008 4.45e-89 269.0 COG3658@1|root,COG3658@2|Bacteria,1PCRS@1224|Proteobacteria,1S5C0@1236|Gammaproteobacteria,46AVI@72275|Alteromonadaceae 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_3459_2 1298593.TOL_1458 3.88e-70 218.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1S3YY@1236|Gammaproteobacteria,1XJT0@135619|Oceanospirillales 135619|Oceanospirillales T response regulator nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg k141_3459_3 251221.35214529 2.17e-22 97.8 COG0715@1|root,COG0715@2|Bacteria,1G3UF@1117|Cyanobacteria 1117|Cyanobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2,TAT_signal k141_18770_1 1160707.AJIK01000003_gene697 6.79e-05 51.6 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26DY7@186818|Planococcaceae 91061|Bacilli NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_6800_1 572477.Alvin_1131 8.79e-151 438.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1WWW0@135613|Chromatiales 135613|Chromatiales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C k141_8954_1 1123355.JHYO01000024_gene1785 1.99e-11 65.5 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,36XAS@31993|Methylocystaceae 28211|Alphaproteobacteria C NADH dehydrogenase nuoH GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_8954_2 658187.LDG_8785 5.2e-58 206.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1JCIN@118969|Legionellales 118969|Legionellales C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3 k141_1377_1 870187.Thini_1695 7.16e-95 285.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,463MH@72273|Thiotrichales 72273|Thiotrichales IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_21572_1 396588.Tgr7_2900 3.32e-74 254.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_2704_1 322710.Avin_11920 5.08e-56 192.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_5536_1 1278309.KB907100_gene1949 2e-265 759.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIUY@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR,TPP_enzyme_C k141_2005_1 1283300.ATXB01000001_gene606 3.98e-93 302.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XDX0@135618|Methylococcales 135618|Methylococcales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_20030_1 395493.BegalDRAFT_2793 1.69e-142 414.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,45ZV6@72273|Thiotrichales 72273|Thiotrichales E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_11739_1 679197.HMPREF9336_02273 1.8e-16 82.0 COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigE GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_13238_1 1288826.MSNKSG1_08673 6.59e-132 391.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_9640_1 395493.BegalDRAFT_0029 5.84e-27 102.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,4610Q@72273|Thiotrichales 72273|Thiotrichales S Stringent starvation protein B - - - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_9640_2 396588.Tgr7_0752 1.53e-64 204.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1WWWN@135613|Chromatiales 135613|Chromatiales O PFAM Glutathione S-transferase sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_C_2,GST_N_3 k141_11130_1 1042375.AFPL01000013_gene2466 1.08e-126 374.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB k141_11130_2 1042375.AFPL01000013_gene2465 1.1e-45 149.0 COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria,4682B@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD NADP transhydrogenase alpha subunit - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM k141_11130_3 1042375.AFPL01000013_gene2464 5.92e-08 54.7 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,4658N@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_3460_1 323848.Nmul_A1042 7.16e-09 56.2 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,371NM@32003|Nitrosomonadales 28216|Betaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_22252_1 765914.ThisiDRAFT_2068 7.64e-37 137.0 COG1573@1|root,COG3210@1|root,COG1573@2|Bacteria,COG3210@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_22252_2 1415779.JOMH01000001_gene2836 1.13e-17 79.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales 135614|Xanthomonadales K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_16007_1 686578.AFFX01000006_gene3254 1.5e-35 130.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_16007_2 349521.HCH_07081 2.05e-119 348.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1XHC3@135619|Oceanospirillales 135619|Oceanospirillales D Chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_7588_1 1278309.KB907102_gene236 6.82e-257 722.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XHXE@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 k141_7588_2 1278309.KB907102_gene237 6.09e-75 229.0 COG0545@1|root,COG0545@2|Bacteria,1RK5W@1224|Proteobacteria,1S8HP@1236|Gammaproteobacteria,1XKDW@135619|Oceanospirillales 135619|Oceanospirillales O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase - - - - - - - - - - - - FKBP_C,FKBP_N k141_7588_3 1278309.KB907102_gene238 3.9e-262 724.0 COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria,1XHXD@135619|Oceanospirillales 135619|Oceanospirillales E M18 family aminopeptidase - - 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 k141_7588_5 1238450.VIBNISOn1_920023 2.09e-197 554.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RRF1@1236|Gammaproteobacteria,1XTQ6@135623|Vibrionales 135623|Vibrionales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_7588_6 1122599.AUGR01000002_gene3312 9.2e-85 255.0 COG4665@1|root,COG4665@2|Bacteria,1RG47@1224|Proteobacteria,1S3PZ@1236|Gammaproteobacteria,1XJUK@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_4848_1 443152.MDG893_18512 5.8e-266 746.0 COG0840@1|root,COG0840@2|Bacteria,1MWU2@1224|Proteobacteria,1RR1Q@1236|Gammaproteobacteria,4661J@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_4848_2 1288826.MSNKSG1_07638 1.68e-275 753.0 COG1075@1|root,COG1075@2|Bacteria,1PW38@1224|Proteobacteria,1RSQX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M with the alpha beta hydrolase fold - - - - - - - - - - - - DUF676 k141_4848_3 1288826.MSNKSG1_07643 1.77e-87 266.0 2A6N7@1|root,30VG1@2|Bacteria,1RDJ7@1224|Proteobacteria,1S69Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4012_1 1278309.KB907103_gene1050 1.19e-97 291.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XK1Y@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein UspA and related nucleotide-binding ydaA - - ko:K14055 - - - - ko00000 - - - Usp k141_4012_2 1278309.KB907103_gene1051 4.38e-175 490.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XHIX@135619|Oceanospirillales 135619|Oceanospirillales L exodeoxyribonuclease III xthA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_4012_3 1278309.KB907103_gene1052 4.64e-307 839.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XI13@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_4012_4 1278309.KB907103_gene1053 9.75e-183 515.0 COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,1XHDZ@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_4012_5 1278309.KB907103_gene1054 4.35e-259 726.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XIC8@135619|Oceanospirillales 135619|Oceanospirillales P transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_4012_6 177439.DP0702 4.54e-46 157.0 COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,42T7W@68525|delta/epsilon subdivisions,2WNWV@28221|Deltaproteobacteria,2MJSW@213118|Desulfobacterales 28221|Deltaproteobacteria S Uncharacterized protein family UPF0029 - - - - - - - - - - - - DUF1949,UPF0029 k141_20808_1 1288826.MSNKSG1_01963 7.02e-88 267.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RNHA@1236|Gammaproteobacteria,46CTQ@72275|Alteromonadaceae 1236|Gammaproteobacteria V HlyD membrane-fusion protein of T1SS emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_20808_2 1288826.MSNKSG1_01968 0.0 927.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,4672P@72275|Alteromonadaceae 1236|Gammaproteobacteria U Major facilitator superfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_10451_1 1278309.KB907110_gene3179 1.17e-56 199.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1XKK2@135619|Oceanospirillales 135619|Oceanospirillales S MJ0042 family finger-like protein - - - - - - - - - - - - DUF3426,zinc_ribbon_5 k141_2018_1 1288826.MSNKSG1_07268 8.03e-12 63.2 COG1309@1|root,COG1309@2|Bacteria,1R13H@1224|Proteobacteria,1SD8W@1236|Gammaproteobacteria,4697I@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N k141_2018_3 1288826.MSNKSG1_07258 4.89e-167 479.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4656N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_17359_1 301.JNHE01000001_gene150 3.14e-19 84.0 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,1YJFS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - - - - - - - - - - PilZ k141_17359_2 1278309.KB907100_gene1983 0.0 1038.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1XH7E@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_20825_1 1415780.JPOG01000001_gene2620 5.25e-51 181.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1X5JF@135614|Xanthomonadales 135614|Xanthomonadales E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_16028_1 1232683.ADIMK_3886 8.27e-139 398.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,46519@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine dehydratase tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_16670_1 713586.KB900536_gene1052 1.73e-33 122.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_16670_2 686578.AFFX01000002_gene786 5.99e-15 73.9 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_4025_1 1499498.EV05_1468 4.21e-49 169.0 COG0320@1|root,COG0320@2|Bacteria,1G0JA@1117|Cyanobacteria,1MKPZ@1212|Prochloraceae 1117|Cyanobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA2 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_6213_1 1288826.MSNKSG1_00226 1.56e-72 223.0 COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,4678K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_6213_2 1288826.MSNKSG1_00231 7.08e-152 430.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,4677I@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_6813_1 1279017.AQYJ01000020_gene1244 1.46e-39 156.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_6813_2 1502851.FG93_03903 4.52e-51 176.0 COG3503@1|root,COG3503@2|Bacteria,1RA1Q@1224|Proteobacteria,2U5Y1@28211|Alphaproteobacteria,3K3W1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1624) - - - - - - - - - - - - DUF1624 k141_8974_1 998674.ATTE01000001_gene499 3.2e-07 52.8 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,46093@72273|Thiotrichales 72273|Thiotrichales LU TIGRFAM DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_8974_2 1026882.MAMP_00785 1.72e-108 329.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales 72273|Thiotrichales S Lysin motif - - - - - - - - - - - - LysM k141_8974_3 1283300.ATXB01000001_gene1101 1.47e-72 223.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1XF14@135618|Methylococcales 135618|Methylococcales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_8974_4 1122211.JMLW01000003_gene1845 8.56e-39 138.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XIP5@135619|Oceanospirillales 135619|Oceanospirillales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_20826_1 1137799.GZ78_21080 8.76e-60 198.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales 135619|Oceanospirillales J SAM-dependent - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_9651_1 1288826.MSNKSG1_14407 0.0 1037.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T3JY@1236|Gammaproteobacteria,46891@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_9651_2 1288826.MSNKSG1_14402 9.23e-80 246.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,463ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_7620_2 643867.Ftrac_0001 2.74e-42 152.0 COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,47KR6@768503|Cytophagia 976|Bacteroidetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_15205_1 335543.Sfum_2600 8.73e-113 338.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales 28221|Deltaproteobacteria L PFAM transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_6214_1 697282.Mettu_4020 9.23e-48 166.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1XE7S@135618|Methylococcales 135618|Methylococcales S Belongs to the RtcB family rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_6214_2 358220.C380_02750 1.14e-30 121.0 COG2770@1|root,COG5001@1|root,COG2770@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,4AAUI@80864|Comamonadaceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_3 k141_4026_1 857087.Metme_3466 1.28e-14 67.8 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XFQ0@135618|Methylococcales 135618|Methylococcales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_4026_2 472759.Nhal_2798 2.18e-46 158.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_19592_1 1123517.JOMR01000001_gene1535 0.000207 43.1 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,46056@72273|Thiotrichales 72273|Thiotrichales P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 k141_19592_2 644801.Psest_0222 7.83e-63 201.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1Z1PF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k141_17482_1 1278309.KB907099_gene2753 3.44e-163 470.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,1XHPP@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha k141_17482_2 1042375.AFPL01000010_gene449 2.79e-30 109.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,467XS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the urease beta subunit family ureB GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_1322,iECO103_1326.ECO103_3798,iECO111_1330.ECO111_1228,iECSP_1301.ECSP_1250,iECs_1301.ECs1323,iUMNK88_1353.UMNK88_1200,iZ_1308.Z1144,iZ_1308.Z1583 Urease_beta k141_2863_1 83219.PM02_19320 4.14e-23 90.1 2FBUW@1|root,343ZG@2|Bacteria,1P0IY@1224|Proteobacteria,2UU2H@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_9142_2 1342299.Z947_2520 3.61e-68 211.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,3ZVEX@60136|Sulfitobacter 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_13350_1 1166948.JPZL01000003_gene437 3.15e-40 149.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XHIH@135619|Oceanospirillales 135619|Oceanospirillales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_18905_1 1278309.KB907108_gene1581 3.78e-130 371.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria,1XI6P@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N k141_18905_2 269482.Bcep1808_5039 2.56e-09 58.5 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJ59@28216|Betaproteobacteria,1K40M@119060|Burkholderiaceae 28216|Betaproteobacteria E PFAM extracellular solute-binding protein family 1 - - - ko:K02055,ko:K11069 ko02010,ko02024,map02010,map02024 M00193,M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11,3.A.1.11.1 - - SBP_bac_8 k141_7050_2 316067.Geob_2748 5.3e-41 139.0 2E3G3@1|root,32YEY@2|Bacteria,1N87D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_7050_3 1417296.U879_07455 6.11e-26 97.8 2BZQB@1|root,32Y98@2|Bacteria,1R3P4@1224|Proteobacteria,2UFWD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_4253_1 335543.Sfum_2391 6.67e-46 166.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria 28221|Deltaproteobacteria V PFAM ABC transporter - - - ko:K01990,ko:K01992,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC2_membrane_3,ABC_tran k141_8443_1 1278309.KB907099_gene2472 5.84e-224 624.0 COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,1XHUV@135619|Oceanospirillales 135619|Oceanospirillales C Domain of unknown function (DUF3390) - - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_7,Fer4_8,LUD_dom k141_21049_1 323261.Noc_2805 2.42e-152 442.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales 135613|Chromatiales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_5690_1 1121403.AUCV01000012_gene4095 7.92e-27 111.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9 k141_18210_1 1288826.MSNKSG1_10053 2.91e-37 130.0 2ED96@1|root,3375M@2|Bacteria,1QXX5@1224|Proteobacteria,1T3IY@1236|Gammaproteobacteria,46DDF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF642) - - - - - - - - - - - - DUF642,VPEP k141_18210_2 1288826.MSNKSG1_10048 2.28e-154 434.0 COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,1RRTJ@1236|Gammaproteobacteria,46807@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_18210_3 1288826.MSNKSG1_10043 0.0 920.0 COG1704@1|root,COG1704@2|Bacteria,1NS0H@1224|Proteobacteria,1SKFZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S E3 Ubiquitin ligase - - - - - - - - - - - - GIDE,LemA k141_19593_1 314278.NB231_06950 9.76e-33 128.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales 135613|Chromatiales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_10559_1 1122599.AUGR01000008_gene2543 1.23e-74 243.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XHPZ@135619|Oceanospirillales 135619|Oceanospirillales GM Polysaccharide biosynthesis protein wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_10559_2 511062.GU3_12800 1.37e-99 292.0 COG2148@1|root,COG2148@2|Bacteria,1R4J5@1224|Proteobacteria,1RP9R@1236|Gammaproteobacteria,1Y5MD@135624|Aeromonadales 135624|Aeromonadales M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf k141_10559_3 270374.MELB17_08391 6.38e-127 371.0 COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,466A3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Nad-dependent epimerase dehydratase galE-1 - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_14754_1 643867.Ftrac_3330 1.84e-29 120.0 COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,47JWJ@768503|Cytophagia 976|Bacteroidetes D Peptidase, M23 envC - - - - - - - - - - - Peptidase_M23 k141_13365_1 90814.KL370892_gene2281 1.7e-49 162.0 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,4633S@72273|Thiotrichales 72273|Thiotrichales - - - - - ko:K09004 - - - - ko00000 - - - DrsE k141_13365_2 317025.Tcr_2156 6.12e-25 102.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S3GT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_13365_3 580332.Slit_1701 1.27e-32 126.0 COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,2VTJT@28216|Betaproteobacteria 28216|Betaproteobacteria K AntiSigma factor - - - - - - - - - - - - - k141_6363_2 472759.Nhal_0556 8.01e-108 330.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1WX3X@135613|Chromatiales 135613|Chromatiales N PFAM ABC-type uncharacterised transport system - - - - - - - - - - - - ABC_transp_aux k141_18923_1 1121949.AQXT01000002_gene2379 7.39e-99 313.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,43WT3@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_9842_2 686340.Metal_3491 3.82e-28 116.0 COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,1RYHZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF,GAF_3,HATPase_c,HDOD k141_7063_1 1288826.MSNKSG1_06523 1.06e-19 87.4 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_7063_2 1288826.MSNKSG1_06518 5.63e-224 616.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,464DE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_7063_3 1288826.MSNKSG1_06513 4.03e-148 417.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,466TM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_7063_4 1288826.MSNKSG1_06508 1.15e-170 483.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,464FS@72275|Alteromonadaceae 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_1484_1 1278309.KB907101_gene279 1.88e-15 85.5 COG1361@1|root,COG2304@1|root,COG2931@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1XK3E@135619|Oceanospirillales 135619|Oceanospirillales Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - VWA_2 k141_72_1 351348.Maqu_0209 1.16e-158 454.0 COG0582@1|root,COG0582@2|Bacteria,1R5TQ@1224|Proteobacteria,1RY85@1236|Gammaproteobacteria,46AI6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Phage integrase family protein - - - - - - - - - - - - Phage_integrase k141_7784_1 1278309.KB907105_gene1548 4.35e-302 828.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XING@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_7784_2 1278309.KB907105_gene1547 9.3e-161 463.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XIXJ@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_7784_3 1278309.KB907105_gene1546 1.98e-113 330.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1XKNB@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 k141_7784_4 1278309.KB907105_gene1545 2.63e-124 364.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XIK3@135619|Oceanospirillales 135619|Oceanospirillales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_797_1 1249627.D779_0983 2.46e-92 277.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_797_2 1357275.AVEL02000109_gene4320 3.9e-106 328.0 COG0688@1|root,COG2897@1|root,COG0688@2|Bacteria,COG2897@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1Z5H7@136849|Pseudomonas syringae group 1236|Gammaproteobacteria I Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_797_4 1158345.JNLL01000001_gene2009 1.5e-23 100.0 COG1999@1|root,COG1999@2|Bacteria,2G55X@200783|Aquificae 200783|Aquificae S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_2175_1 1132855.KB913035_gene1770 3.69e-193 545.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_38,rve k141_12650_1 1288826.MSNKSG1_06333 0.0 2345.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4643G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine synthase metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_12650_2 1288826.MSNKSG1_06338 6.85e-44 143.0 2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,1SGBH@1236|Gammaproteobacteria,468VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2970) - - - - - - - - - - - - DUF2970 k141_5707_1 1278309.KB907099_gene2401 4.61e-277 762.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XI6I@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_5707_2 1278309.KB907099_gene2400 9.42e-136 386.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XIPY@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG - 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG k141_5707_3 1278309.KB907099_gene2399 2.69e-277 761.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1XIJG@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_5707_4 1278309.KB907099_gene2398 2.12e-47 152.0 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,1XKZ8@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the BolA IbaG family - - - - - - - - - - - - BolA k141_5707_5 1278309.KB907099_gene2397 2.75e-24 95.1 2EH0C@1|root,33ASF@2|Bacteria,1QTNR@1224|Proteobacteria,1RXSI@1236|Gammaproteobacteria,1XMVW@135619|Oceanospirillales 135619|Oceanospirillales S STAS domain - - - - - - - - - - - - STAS_2 k141_5707_6 1042375.AFPL01000025_gene1171 5.03e-55 181.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1SABB@1236|Gammaproteobacteria,467R8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component ttg2D - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_5707_7 1042375.AFPL01000025_gene1172 2.73e-66 205.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,4678T@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, periplasmic component mlaD GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_5707_8 1278309.KB907099_gene2394 6.93e-153 433.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1XIPT@135619|Oceanospirillales 135619|Oceanospirillales Q (ABC) transporter, permease - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_5707_9 207954.MED92_01619 6.33e-154 437.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XI6F@135619|Oceanospirillales 135619|Oceanospirillales Q ABC transporter maintaining outer membrane lipid asymmetry - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_5707_10 1278309.KB907099_gene2392 2.17e-176 497.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XHJ1@135619|Oceanospirillales 135619|Oceanospirillales P antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_5707_11 1278309.KB907099_gene2391 3.03e-197 550.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1XI8M@135619|Oceanospirillales 135619|Oceanospirillales M Arabinose 5-phosphate isomerase kpsF - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_18924_1 672.VV93_v1c17800 6.18e-37 141.0 COG3713@1|root,COG3713@2|Bacteria,1MXXC@1224|Proteobacteria,1RYNJ@1236|Gammaproteobacteria,1XU8E@135623|Vibrionales 135623|Vibrionales M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA k141_8465_1 1469613.JT55_00785 1.52e-105 322.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,3FCIG@34008|Rhodovulum 28211|Alphaproteobacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k141_16114_1 1123401.JHYQ01000025_gene3302 1.32e-18 81.6 COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,1S5W6@1236|Gammaproteobacteria,461FH@72273|Thiotrichales 72273|Thiotrichales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_16114_2 237368.SCABRO_01914 8.53e-23 99.8 COG1043@1|root,COG1043@2|Bacteria,2IYJJ@203682|Planctomycetes 203682|Planctomycetes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_15471_1 1288826.MSNKSG1_05081 8.31e-267 743.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,463XW@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_15471_2 1288826.MSNKSG1_05086 1.91e-156 439.0 28NH4@1|root,2ZBJ2@2|Bacteria,1N1V3@1224|Proteobacteria,1T0IS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15471_3 1288826.MSNKSG1_05091 1.05e-95 279.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,467I4@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_15471_4 1288826.MSNKSG1_05096 3.75e-178 498.0 2EEZV@1|root,338SY@2|Bacteria,1NF4V@1224|Proteobacteria,1SFQH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15471_5 1288826.MSNKSG1_05101 0.0 1383.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,4644P@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_0614,iNRG857_1313.NRG857_19200 3HCDH,3HCDH_N,ECH_1 k141_15471_6 1288826.MSNKSG1_05106 1.19e-279 764.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464KF@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2612,iECNA114_1301.ECNA114_4154,iECOK1_1307.ECOK1_4314,iECP_1309.ECP_4058,iECS88_1305.ECS88_4293,iECSF_1327.ECSF_3702,iEcE24377_1341.EcE24377A_4364,iLF82_1304.LF82_0613,iNRG857_1313.NRG857_19195,iPC815.YPO3767 Thiolase_C,Thiolase_N k141_4959_2 1121935.AQXX01000142_gene2325 4.6e-82 250.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,1XNAN@135619|Oceanospirillales 135619|Oceanospirillales S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_6364_1 1123366.TH3_13339 1.61e-17 89.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2JPKF@204441|Rhodospirillales 204441|Rhodospirillales M COG3264 Small-conductance mechanosensitive channel - - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - DUF3772,MS_channel k141_6364_2 396588.Tgr7_2235 5.87e-39 135.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_4272_1 1122201.AUAZ01000005_gene601 2.25e-153 454.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,465N7@72275|Alteromonadaceae 1236|Gammaproteobacteria S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_11288_1 643867.Ftrac_2414 1.19e-47 168.0 28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_11288_2 1237149.C900_05597 9.57e-12 65.1 COG1361@1|root,COG1361@2|Bacteria,4PKPA@976|Bacteroidetes 976|Bacteroidetes M Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,CARDB k141_20346_1 1249627.D779_0852 5.3e-36 137.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_20346_2 1120999.JONM01000010_gene4185 1.2e-61 195.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,2KR45@206351|Neisseriales 206351|Neisseriales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_21673_1 697282.Mettu_0058 5.62e-97 303.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XE2C@135618|Methylococcales 135618|Methylococcales KL HELICc2 - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2 k141_14049_3 946483.Cenrod_1539 2.73e-40 153.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG2204@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS_9,Response_reg k141_18926_1 713587.THITH_05065 3.21e-30 115.0 COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,1S971@1236|Gammaproteobacteria,1WYN8@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 k141_18222_2 1288826.MSNKSG1_18240 1.19e-117 337.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,4643Y@72275|Alteromonadaceae 1236|Gammaproteobacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_18222_3 1288826.MSNKSG1_18235 5.27e-298 815.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,464C4@72275|Alteromonadaceae 1236|Gammaproteobacteria O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_18222_4 1288826.MSNKSG1_18230 4.46e-293 800.0 COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,1RRTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_18222_5 1288826.MSNKSG1_18225 0.0 1477.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,464IT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_18222_6 1288826.MSNKSG1_18220 2.24e-131 372.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,4672S@72275|Alteromonadaceae 1236|Gammaproteobacteria L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_18222_7 1288826.MSNKSG1_18215 4.69e-158 442.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,466GA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0560 Phosphoserine phosphatase - - - - - - - - - - - - HAD k141_7787_1 889378.Spiaf_2449 2.3e-101 301.0 COG0031@1|root,COG0031@2|Bacteria,2J5EE@203691|Spirochaetes 203691|Spirochaetes E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K01738,ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_7787_2 658187.LDG_6853 1.79e-06 48.5 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria,1JDCE@118969|Legionellales 118969|Legionellales L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k141_10560_1 351348.Maqu_0210 5.69e-72 240.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria,46AHK@72275|Alteromonadaceae 1236|Gammaproteobacteria L Putative phage integrase - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_integrase k141_10560_2 351348.Maqu_0210 1.38e-43 158.0 COG0582@1|root,COG0582@2|Bacteria,1MV71@1224|Proteobacteria,1RQMW@1236|Gammaproteobacteria,46AHK@72275|Alteromonadaceae 1236|Gammaproteobacteria L Putative phage integrase - - - - - - - - - - - - PHINT_rpt,Phage_Integr_2,Phage_integrase k141_3595_1 717774.Marme_2620 1.13e-34 121.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1XKG4@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_5085_1 395493.BegalDRAFT_2678 7.38e-44 161.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,45ZVF@72273|Thiotrichales 72273|Thiotrichales NU Type II and III secretion system protein - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_19076_1 1286106.MPL1_05374 3.04e-199 566.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales 72273|Thiotrichales EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_19076_2 1158762.KB898037_gene2325 1.7e-23 98.2 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RY1Q@1236|Gammaproteobacteria,1WX7C@135613|Chromatiales 135613|Chromatiales L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_21195_2 1121935.AQXX01000135_gene3698 8.97e-68 218.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1XH3N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K11961 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_907_1 292415.Tbd_1549 1.08e-87 265.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KS53@119069|Hydrogenophilales 119069|Hydrogenophilales IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_4422_1 161528.ED21_23766 1.54e-36 145.0 COG4105@1|root,COG4571@1|root,COG4105@2|Bacteria,COG4571@2|Bacteria,1QWIQ@1224|Proteobacteria,2VAKE@28211|Alphaproteobacteria,2K2FT@204457|Sphingomonadales 204457|Sphingomonadales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - k141_12087_1 999611.KI421504_gene3358 2.1e-62 211.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,280B0@191028|Leisingera 28211|Alphaproteobacteria I Methylmalonyl-CoA mutase bhbA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_7182_1 391616.OA238_c48580 1.35e-26 103.0 COG0859@1|root,COG0859@2|Bacteria,1MZGQ@1224|Proteobacteria,2UC9D@28211|Alphaproteobacteria 28211|Alphaproteobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - - k141_7182_2 1121012.AUKX01000003_gene1480 5.85e-22 94.7 COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1HYH4@117743|Flavobacteriia,23GJM@178469|Arenibacter 976|Bacteroidetes M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k141_14173_1 637390.AFOH01000042_gene2250 9.37e-07 52.0 COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,1RRSW@1236|Gammaproteobacteria,2NCYM@225057|Acidithiobacillales 225057|Acidithiobacillales M Capsule polysaccharide biosynthesis protein - - - ko:K07265 - - - - ko00000 - - - Capsule_synth k141_7906_1 631362.Thi970DRAFT_01382 2.56e-243 679.0 COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales 135613|Chromatiales C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_17,Fer4_8 k141_7906_2 2340.JV46_15440 2.2e-84 267.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster dsrL - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,NADH_4Fe-4S,Pyr_redox_2 k141_6471_1 367336.OM2255_13017 1.31e-106 321.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_10707_1 1122179.KB890468_gene451 3.03e-23 95.1 COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IT21@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 k141_16944_1 1163617.SCD_n02177 2.24e-108 332.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria 28216|Betaproteobacteria V Abc transporter atm1 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_3021_1 1278309.KB907104_gene970 4.85e-50 163.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1XKST@135619|Oceanospirillales 135619|Oceanospirillales I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_3021_2 1278309.KB907104_gene969 1.45e-243 691.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_13471_2 1168067.JAGP01000001_gene321 7.21e-19 80.1 COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,1SD0H@1236|Gammaproteobacteria,46190@72273|Thiotrichales 72273|Thiotrichales P Heavy-metal-associated domain - - - ko:K07213 ko04978,map04978 - - - ko00000,ko00001 - - - HMA k141_3720_1 1288298.rosmuc_00050 2.12e-55 190.0 COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2TTJ6@28211|Alphaproteobacteria,46NRZ@74030|Roseovarius 28211|Alphaproteobacteria P COG1176 ABC-type spermidine putrescine transport system, permease component I potB - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 k141_9242_1 643867.Ftrac_2517 3.67e-74 238.0 COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_1622_1 1278309.KB907100_gene2041 8.77e-203 577.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XI3G@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_1622_2 1278309.KB907100_gene2040 1.39e-184 518.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XH8Q@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12,1.2.1.72 ko:K00134,ko:K03472 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 R01061,R01825 RC00149,RC00242 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_14174_1 1278309.KB907099_gene2555 7.34e-113 332.0 COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1XISV@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds - - 4.1.3.39,4.1.3.43 ko:K01666,ko:K18365 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750,R05298 RC00307,RC00371,RC00572 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k141_21832_1 90814.KL370891_gene504 7.36e-18 86.3 COG1801@1|root,COG1801@2|Bacteria,1NJGC@1224|Proteobacteria,1SHUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - - k141_9933_1 1278309.KB907102_gene251 5.47e-138 413.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RPZD@1236|Gammaproteobacteria,1XHMC@135619|Oceanospirillales 135619|Oceanospirillales K Ribonuclease R winged-helix domain - - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_9933_2 696281.Desru_0822 1.43e-123 418.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k141_9933_3 207954.MED92_07836 7.11e-90 281.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1XHYU@135619|Oceanospirillales 135619|Oceanospirillales G Alpha amylase, catalytic domain - - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_12088_1 1144319.PMI16_02085 9.33e-32 122.0 COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VNYN@28216|Betaproteobacteria,4733Q@75682|Oxalobacteraceae 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 k141_7183_1 314271.RB2654_11823 6.86e-78 234.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase gloA GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_7183_2 744980.TRICHSKD4_2191 8.05e-24 99.4 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k141_4424_1 1122197.ATWI01000011_gene436 6.15e-106 332.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_19722_2 523791.Kkor_0173 1.52e-27 105.0 COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,1XKT3@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the frataxin family cyaY - - ko:K06202 - - - - ko00000 - - - Frataxin_Cyay k141_1623_1 1320556.AVBP01000011_gene3363 8.17e-67 210.0 COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2TRVQ@28211|Alphaproteobacteria,43MHJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Aspartyl/Asparaginyl beta-hydroxylase MA20_07860 - 1.14.11.16 ko:K00476,ko:K12979 - - - - ko00000,ko01000,ko01005 - - - Asp_Arg_Hydrox k141_8593_1 1278309.KB907104_gene868 7.01e-88 258.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1XKAV@135619|Oceanospirillales 135619|Oceanospirillales O redox protein, regulator of disulfide bond formation - - - ko:K07397 - - - - ko00000 - - - OsmC k141_8593_2 1278309.KB907104_gene867 1.74e-154 438.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1XIIP@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the TrpC family trpC - 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS k141_8593_3 1232683.ADIMK_0443 4.21e-137 395.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_3023_1 999547.KI421500_gene521 2.37e-36 136.0 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,280TB@191028|Leisingera 28211|Alphaproteobacteria H Cobalamin biosynthesis protein CobT VWA domain cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C k141_3023_2 999550.KI421507_gene830 1.71e-44 152.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S cobaltochelatase, CobS subunit cobS - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N k141_20478_1 686340.Metal_0843 1.27e-29 117.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XENK@135618|Methylococcales 135618|Methylococcales M Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_21834_1 519989.ECTPHS_02886 4.33e-11 68.6 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,1WXWT@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_12089_2 1288826.MSNKSG1_13137 2.11e-108 333.0 COG3221@1|root,COG5001@1|root,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,46DBB@72275|Alteromonadaceae 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_12792_1 1163617.SCD_n01448 1.98e-60 190.0 2B9TV@1|root,3236R@2|Bacteria,1RKIZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_12792_2 56780.SYN_02345 9.99e-16 74.3 2DRJZ@1|root,33C4Q@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_18351_1 1122599.AUGR01000014_gene555 2.29e-89 270.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XIT9@135619|Oceanospirillales 1236|Gammaproteobacteria E phosphoserine phosphatase - - - - - - - - - - - - HAD k141_18351_2 357804.Ping_3162 2.43e-147 422.0 COG1524@1|root,COG1524@2|Bacteria,1MYH0@1224|Proteobacteria,1RNQJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S proteins of the AP superfamily - - - - - - - - - - - - Phosphodiest k141_18351_3 207954.MED92_13031 8.04e-173 509.0 COG0840@1|root,COG0840@2|Bacteria,1NR89@1224|Proteobacteria,1SKCC@1236|Gammaproteobacteria,1XNCA@135619|Oceanospirillales 135619|Oceanospirillales T Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_18351_4 1278309.KB907099_gene2432 1.57e-34 122.0 28YQD@1|root,2ZKHY@2|Bacteria,1PAH9@1224|Proteobacteria,1SU6Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phasin protein - - - - - - - - - - - - Phasin_2 k141_9243_1 396588.Tgr7_2900 1.87e-111 367.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_203_1 1278309.KB907100_gene2177 0.0 1353.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIXK@135619|Oceanospirillales 135619|Oceanospirillales C COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits - - - - - - - - - - - - POR k141_203_2 1278309.KB907100_gene2176 2.36e-84 250.0 COG1522@1|root,COG1522@2|Bacteria,1R7SW@1224|Proteobacteria,1S4QN@1236|Gammaproteobacteria,1XJSC@135619|Oceanospirillales 135619|Oceanospirillales K COG1522 Transcriptional regulators - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_13473_1 1266908.AQPB01000051_gene2446 2.13e-76 244.0 COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_16946_1 388401.RB2150_11671 1.49e-126 373.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TUXZ@28211|Alphaproteobacteria,3ZGZZ@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_19723_1 391598.FBBAL38_04640 1.07e-09 65.1 28PY8@1|root,2ZCHZ@2|Bacteria,4NMGG@976|Bacteroidetes,1I1JV@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_9935_1 416269.APL_1089 3.96e-22 90.9 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S3Z8@1236|Gammaproteobacteria,1Y9G6@135625|Pasteurellales 135625|Pasteurellales C arsenate reductase - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_9935_2 1122169.AREN01000052_gene224 3.11e-79 241.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1JD7D@118969|Legionellales 118969|Legionellales S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_20479_1 391615.ABSJ01000004_gene651 8.03e-95 284.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1J51I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 Aminotran_4 k141_14880_1 317025.Tcr_1797 1.72e-199 569.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZPC@72273|Thiotrichales 72273|Thiotrichales G PFAM alpha amylase, catalytic - - 2.4.1.4 ko:K05341 ko00500,map00500 - R01823 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_9244_1 1278309.KB907099_gene2801 4.74e-88 285.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_3038_5 1123228.AUIH01000011_gene2121 5.36e-64 197.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XJH4@135619|Oceanospirillales 135619|Oceanospirillales K at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) glnK-2 - - ko:K04752 - - - - ko00000 - - - P-II k141_3038_6 550540.Fbal_3405 4.98e-100 302.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006553,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009058,GO:0009064,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 ko:K00821,ko:K00840 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04217,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSFV_1184.SFV_3365,iSF_1195.SF3378,iSFxv_1172.SFxv_3689,iSSON_1240.SSON_3490,iS_1188.S4385 Aminotran_3 k141_11413_1 744980.TRICHSKD4_1923 3.42e-20 98.2 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2U4EG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T signal transduction histidine kinase - - - - - - - - - - - - CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg k141_16238_2 87626.PTD2_22222 1.03e-06 51.6 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q1JS@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_21201_1 926569.ANT_09180 6.21e-07 60.8 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - ko:K13009,ko:K18814 - - - - ko00000,ko01000,ko01005,ko02000 9.B.67.1 - - Wzy_C k141_12103_1 1492922.GY26_12330 7.31e-05 47.8 2DT26@1|root,33IBU@2|Bacteria,1NNDF@1224|Proteobacteria,1SSB3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4376) - - - - - - - - - - - - DUF4376 k141_12103_2 1523503.JPMY01000010_gene2747 2.78e-13 76.3 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins psmE - - - - - - - - - - - Beta_helix,Cadherin_3,DUF4114,He_PIG,HemolysinCabind,Pectate_lyase_3,Peptidase_M10,Peptidase_M10_C k141_19092_2 1288826.MSNKSG1_05111 0.0 1743.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,463YR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_21852_1 1278309.KB907105_gene1427 7.66e-52 180.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XI30@135619|Oceanospirillales 135619|Oceanospirillales I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_21852_2 1278309.KB907105_gene1426 1.8e-111 323.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,1XK93@135619|Oceanospirillales 135619|Oceanospirillales I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase k141_21852_3 1278309.KB907105_gene1425 5.18e-112 328.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1S1Z5@1236|Gammaproteobacteria,1XJQW@135619|Oceanospirillales 135619|Oceanospirillales I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 k141_21852_4 1278309.KB907105_gene1423 0.0 936.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XICJ@135619|Oceanospirillales 135619|Oceanospirillales IQ involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_21852_5 1278309.KB907105_gene1422 7.16e-48 156.0 COG3255@1|root,COG3255@2|Bacteria,1N206@1224|Proteobacteria,1S8RI@1236|Gammaproteobacteria,1XKS6@135619|Oceanospirillales 135619|Oceanospirillales I sterol carrier protein - - - - - - - - - - - - SCP2 k141_21852_6 1278309.KB907105_gene1421 2.21e-221 623.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1XHAP@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_9948_2 1384054.N790_06475 2.9e-22 104.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQ9@1236|Gammaproteobacteria,1X410@135614|Xanthomonadales 135614|Xanthomonadales S Ubiquinone biosynthesis protein - - - ko:K03688 - - - - ko00000 - - - ABC1 k141_219_1 1198232.CYCME_1713 1.5e-74 237.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,45ZUN@72273|Thiotrichales 72273|Thiotrichales E Amino acid kinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k141_219_2 1122599.AUGR01000009_gene2437 9.99e-12 63.9 COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,1RSBY@1236|Gammaproteobacteria,1XHRB@135619|Oceanospirillales 135619|Oceanospirillales Q Phytanoyl-CoA dioxygenase (PhyH) ectD - 1.14.11.55 ko:K10674 ko00260,ko01120,map00260,map01120 - R08050 RC00661 ko00000,ko00001,ko01000 - - - PhyH k141_20491_1 709032.Sulku_2130 4.34e-08 55.8 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2YQJT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Glycosyl transferase 4-like - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 k141_20491_2 563040.Saut_1557 1.07e-24 103.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,42MJR@68525|delta/epsilon subdivisions,2YMAJ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Heptosyltransferase III waaQ - - ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_1640_1 323261.Noc_1690 1.05e-30 117.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1WZS4@135613|Chromatiales 135613|Chromatiales S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 k141_21202_1 595494.Tola_0775 5.6e-91 276.0 COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,1RQKH@1236|Gammaproteobacteria,1Y3G9@135624|Aeromonadales 135624|Aeromonadales K Transcriptional regulator - - - ko:K06145,ko:K06146 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 k141_16969_1 323261.Noc_0241 1.11e-44 162.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales 135613|Chromatiales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_16969_2 1209072.ALBT01000052_gene628 1.58e-05 47.4 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1FFY5@10|Cellvibrio 1236|Gammaproteobacteria P Transporter associated domain corC GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_7939_1 391595.RLO149_c020040 7.3e-134 384.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,2P1U7@2433|Roseobacter 28211|Alphaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm k141_11414_1 1121481.AUAS01000003_gene3920 8.44e-19 89.4 COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C k141_11414_2 1121373.KB903664_gene2715 4.75e-13 65.1 COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,47R3V@768503|Cytophagia 976|Bacteroidetes S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_10720_2 1278309.KB907103_gene1211 5.55e-107 312.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1XK22@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane protein W - - - ko:K07275 - - - - ko00000 - - - OmpW k141_10720_3 1279015.KB908456_gene1562 8.64e-61 206.0 COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,1RZUT@1236|Gammaproteobacteria,1Y4QS@135624|Aeromonadales 135624|Aeromonadales NT Chemoreceptor zinc-binding domain - - - - - - - - - - - - CZB,MCPsignal k141_10720_4 502025.Hoch_5251 3.09e-39 133.0 COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,43BPC@68525|delta/epsilon subdivisions,2X70P@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Cupin domain - - - ko:K11312 - - - - ko00000 - - - Cupin_2 k141_14187_1 1122201.AUAZ01000023_gene3029 3.44e-30 118.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,467IV@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_18370_1 396588.Tgr7_3124 1.77e-186 541.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1WWBM@135613|Chromatiales 135613|Chromatiales E Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N k141_18370_2 1122599.AUGR01000002_gene3358 4.88e-16 77.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XNV7@135619|Oceanospirillales 135619|Oceanospirillales P Na+/H+ antiporter 1 - - - - - - - - - - - - Na_H_antiport_1 k141_14990_3 187272.Mlg_0671 1.64e-50 178.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_3841_2 998674.ATTE01000001_gene4531 1.49e-27 102.0 COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,46353@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 k141_3841_3 1114856.C496_18388 2.65e-45 159.0 COG4923@1|root,arCOG04711@2157|Archaea,2XWTP@28890|Euryarchaeota,23VB8@183963|Halobacteria 183963|Halobacteria S Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 k141_17809_1 1304883.KI912532_gene671 3.67e-100 304.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,2KVCH@206389|Rhodocyclales 28216|Betaproteobacteria T Chemotaxis signal transduction protein cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_17809_2 1278307.KB906982_gene3979 3.52e-39 160.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_17809_3 926692.AZYG01000085_gene852 8.05e-17 78.6 COG2703@1|root,COG2703@2|Bacteria,1UVAX@1239|Firmicutes,25KFK@186801|Clostridia,3WC7M@53433|Halanaerobiales 186801|Clostridia P Hemerythrin HHE cation binding domain - - - ko:K07216 - - - - ko00000 - - - Hemerythrin k141_10855_1 1278309.KB907106_gene1301 1.66e-127 383.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHCB@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_6599_1 690597.JH730931_gene3468 5.13e-43 154.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1YMD3@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C oxaloacetate oadA - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5346 Biotin_lipoyl,HMGL-like,PYC_OADA k141_6599_2 1121374.KB891575_gene1361 2.46e-138 393.0 COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,1SYDI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide cynT GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009439,GO:0009440,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901565,GO:1901575 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - iJN746.PP_0100 Pro_CA k141_6599_3 1278309.KB907111_gene3393 2.83e-179 508.0 COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,1RQ1W@1236|Gammaproteobacteria,1XHVE@135619|Oceanospirillales 135619|Oceanospirillales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_12248_1 322710.Avin_48790 1.59e-125 362.0 COG2242@1|root,COG2242@2|Bacteria,1QWG8@1224|Proteobacteria 1224|Proteobacteria H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 k141_12248_2 1190603.AJYD01000028_gene3764 1.06e-36 127.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS pspE - - ko:K03972 - - - - ko00000 - - - Rhodanese k141_12248_3 1280001.BAOA01000077_gene3077 5.22e-70 212.0 COG1359@1|root,COG1359@2|Bacteria,1RH7B@1224|Proteobacteria,1S6UJ@1236|Gammaproteobacteria,1XXJ4@135623|Vibrionales 135623|Vibrionales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_12248_4 472759.Nhal_1361 2.28e-49 164.0 2DMMP@1|root,32SHG@2|Bacteria,1RM15@1224|Proteobacteria,1SQ5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19869_1 1278309.KB907107_gene1742 1.28e-76 243.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XIAN@135619|Oceanospirillales 135619|Oceanospirillales N Belongs to the bacterial flagellin family flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_19869_3 1278309.KB907107_gene1740 3.94e-70 214.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1XM0Z@135619|Oceanospirillales 135619|Oceanospirillales N flagellar protein FliS fliS - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k141_19869_4 1278309.KB907107_gene1739 2.33e-71 229.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1XKCN@135619|Oceanospirillales 135619|Oceanospirillales N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_15726_2 556268.OFAG_00846 2.05e-33 126.0 COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,2VHQT@28216|Betaproteobacteria,47686@75682|Oxalobacteraceae 28216|Betaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k141_1072_1 458817.Shal_1567 9.58e-07 50.1 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,2QBZ9@267890|Shewanellaceae 1236|Gammaproteobacteria S Belongs to the PsiE family - - - ko:K13256 - - - - ko00000 - - - PsiE k141_8719_1 765912.Thimo_0389 2.11e-106 319.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1WWRH@135613|Chromatiales 1236|Gammaproteobacteria G Fructose-bisphosphate aldolase, class II, Calvin cycle subtype - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - Dabb,F_bP_aldolase k141_13615_1 1232683.ADIMK_2978 7.01e-67 221.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,4660Y@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit hyuA - 3.5.2.14,6.4.1.6 ko:K01473,ko:K10855 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_13615_2 1232683.ADIMK_2979 4.32e-296 823.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria,4679I@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14,6.4.1.6 ko:K01474,ko:K10854 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_10102_1 631362.Thi970DRAFT_02369 1.3e-09 58.9 2DFIC@1|root,2ZRYR@2|Bacteria,1P7J0@1224|Proteobacteria,1SVFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10102_3 1163617.SCD_n02386 3.98e-14 74.3 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM Forkhead-associated protein - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_10102_4 257313.BP1263 2.65e-23 94.7 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,3T488@506|Alcaligenaceae 28216|Betaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_11533_1 2340.JV46_20250 1.29e-87 264.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1J5PU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_8110_2 1278309.KB907107_gene1700 8.77e-165 463.0 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1XHJ3@135619|Oceanospirillales 135619|Oceanospirillales D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_8110_3 1278309.KB907107_gene1701 9.64e-49 164.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1XK89@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar motor protein - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_380_1 1278309.KB907103_gene1161 5.44e-112 333.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1XHG8@135619|Oceanospirillales 135619|Oceanospirillales C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_380_4 1278309.KB907099_gene2583 4.56e-181 511.0 COG0455@1|root,COG0455@2|Bacteria,1R0BV@1224|Proteobacteria 1224|Proteobacteria D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_380_5 1278309.KB907101_gene698 0.0 1267.0 COG1765@1|root,COG1944@1|root,COG1765@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,1XHD4@135619|Oceanospirillales 135619|Oceanospirillales O redox protein, regulator of disulfide bond formation - - - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_380_6 349521.HCH_03647 4.87e-09 61.2 COG0745@1|root,COG5001@1|root,COG0745@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHS3@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg k141_380_7 349124.Hhal_1118 1.39e-42 163.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1S30T@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,Response_reg k141_380_8 1232683.ADIMK_1179 4.14e-53 172.0 COG3915@1|root,COG3915@2|Bacteria,1RHJS@1224|Proteobacteria,1S0M5@1236|Gammaproteobacteria,46D0P@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Oxidored_molyb k141_2447_1 1288826.MSNKSG1_08293 4.55e-113 328.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,465DJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_2447_3 1288826.MSNKSG1_08283 4.89e-171 479.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,464ER@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) cheZ GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564 - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_2447_4 1288826.MSNKSG1_08278 0.0 1075.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,465S1@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_2447_5 1288826.MSNKSG1_08273 6.64e-259 711.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,465TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_2447_6 1288826.MSNKSG1_08268 1.81e-167 469.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria,4667Q@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1291 Flagellar motor component motC - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_2447_7 1288826.MSNKSG1_08263 1.09e-175 491.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,466UE@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1360 Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_2447_8 1288826.MSNKSG1_08258 1.76e-188 523.0 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,464N7@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning XCC1889 - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_2447_9 1288826.MSNKSG1_08253 1.94e-180 504.0 COG0835@1|root,COG3266@1|root,COG0835@2|Bacteria,COG3266@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,466MB@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Two component signalling adaptor domain VP2226 - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_2447_10 1288826.MSNKSG1_08248 2.77e-107 310.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,466IY@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0835 Chemotaxis signal transduction protein cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_2447_11 1288826.MSNKSG1_08243 2.3e-86 254.0 2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S chemotaxis, protein - - - - - - - - - - - - DUF2802 k141_2447_12 1288826.MSNKSG1_08238 1.14e-98 307.0 COG2518@1|root,COG2804@1|root,COG2518@2|Bacteria,COG2804@2|Bacteria,1R5CG@1224|Proteobacteria,1RV00@1236|Gammaproteobacteria,469V8@72275|Alteromonadaceae 1236|Gammaproteobacteria NOU Type II secretion system (T2SS), protein E, N-terminal domain - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - PCMT,T2SSE,T2SSE_N k141_3842_1 1122137.AQXF01000004_gene1449 4.8e-88 267.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_5936_1 1123257.AUFV01000003_gene824 4.91e-66 214.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,1X4IR@135614|Xanthomonadales 135614|Xanthomonadales M Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_5243_1 870187.Thini_2730 6.26e-51 169.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,461N8@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_5243_2 377629.TERTU_3437 1.45e-116 340.0 arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,2PPR1@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_5243_3 765910.MARPU_14405 1.07e-14 74.7 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales 135613|Chromatiales H Belongs to the NadC ModD family - - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N k141_15727_1 580332.Slit_1221 3.16e-43 147.0 2AH6M@1|root,317GF@2|Bacteria,1RKMX@1224|Proteobacteria,2W24R@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_17079_1 1209072.ALBT01000009_gene3016 1.48e-48 171.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1FG97@10|Cellvibrio 1236|Gammaproteobacteria C FAD dependent oxidoreductase eryB - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO k141_19870_1 1049564.TevJSym_ap00490 1.84e-55 188.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1J5NF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_4568_2 1288826.MSNKSG1_05291 1.46e-165 462.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,467KI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Anti-ECFsigma factor ChrR - - - - - - - - - - - - Cupin_7 k141_381_1 91464.S7335_5268 3.71e-31 115.0 COG0393@1|root,COG0393@2|Bacteria,1G7AD@1117|Cyanobacteria,1H2BY@1129|Synechococcus 1117|Cyanobacteria S Putative heavy-metal-binding - - - - - - - - - - - - YbjQ_1 k141_21998_1 396588.Tgr7_0191 1.55e-113 350.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales 135613|Chromatiales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_12946_1 247634.GPB2148_14 1.28e-80 249.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria 1224|Proteobacteria L Transposase and inactivated derivatives - - 2.7.7.49 ko:K00986,ko:K07497 - - - - ko00000,ko01000 - - - HTH_32,rve,rve_3 k141_12946_2 1238182.C882_1323 3.35e-26 99.8 COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria,2JX3Z@204441|Rhodospirillales 204441|Rhodospirillales L Transposase - - - - - - - - - - - - HTH_Tnp_1 k141_14276_2 395493.BegalDRAFT_2892 0.000262 41.6 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,460I0@72273|Thiotrichales 72273|Thiotrichales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N k141_14992_1 1173022.Cri9333_0339 1.08e-29 119.0 COG0675@1|root,COG0675@2|Bacteria,1G01E@1117|Cyanobacteria,1H8K3@1150|Oscillatoriales 1117|Cyanobacteria L COG0675 Transposase and inactivated derivatives - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k141_20623_1 716544.wcw_1398 4.45e-15 79.0 COG0609@1|root,COG0609@2|Bacteria,2JFJ1@204428|Chlamydiae 204428|Chlamydiae P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_10104_1 1384054.N790_01180 1.52e-90 292.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_6600_1 322710.Avin_09030 1.03e-59 205.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k141_17080_1 391626.OAN307_c37110 1.36e-11 62.8 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_17080_2 314270.RB2083_1416 1.15e-28 114.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,3ZGSW@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Permease perM - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_9377_1 555778.Hneap_0135 2.16e-39 158.0 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG0784@2|Bacteria,COG3850@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - 4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg k141_19871_1 595494.Tola_1054 1.16e-95 290.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1Y3DU@135624|Aeromonadales 135624|Aeromonadales L DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_21321_1 1278309.KB907099_gene3092 3.29e-54 171.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SCXD@1236|Gammaproteobacteria,1XKP1@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_21321_2 1278309.KB907099_gene3093 4.41e-156 442.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1RZPB@1236|Gammaproteobacteria,1XJ9B@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_21321_3 1278309.KB907099_gene3094 1.68e-142 405.0 COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,1XJVM@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF599 k141_21321_4 1278309.KB907099_gene3095 0.0 937.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XHR3@135619|Oceanospirillales 135619|Oceanospirillales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_5937_1 1121434.AULY01000007_gene1620 4.56e-55 189.0 COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,2MB2T@213115|Desulfovibrionales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_10105_1 1353528.DT23_07220 1.02e-13 70.5 COG0392@1|root,COG0392@2|Bacteria,1R4IS@1224|Proteobacteria,2U40H@28211|Alphaproteobacteria,2XP0H@285107|Thioclava 28211|Alphaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM k141_10105_2 633131.TR2A62_1873 4.05e-41 147.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria 28211|Alphaproteobacteria C FAD linked oxidase - - 1.1.3.8,1.1.98.3 ko:K00103,ko:K16653 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 k141_18474_1 1278309.KB907107_gene1710 5.79e-280 780.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XH92@135619|Oceanospirillales 135619|Oceanospirillales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_18474_2 1278309.KB907107_gene1709 4.72e-43 153.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1XIUW@135619|Oceanospirillales 135619|Oceanospirillales N SRP54-type protein, GTPase domain - - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_13616_1 305900.GV64_20970 4.54e-155 456.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1XH8T@135619|Oceanospirillales 135619|Oceanospirillales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k141_10133_1 90814.KL370892_gene2304 2.1e-26 113.0 COG5002@1|root,COG5002@2|Bacteria,1QVXJ@1224|Proteobacteria,1T2NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg k141_18498_1 472759.Nhal_2221 5.73e-93 282.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria,1X055@135613|Chromatiales 135613|Chromatiales F PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_16386_1 999611.KI421504_gene2200 1.14e-21 93.2 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,280N4@191028|Leisingera 28211|Alphaproteobacteria J GatB domain gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_16386_2 467661.RKLH11_1068 1.18e-33 129.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,3ZGDW@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E Aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_2470_1 1445613.JALM01000038_gene2968 8.79e-17 79.7 COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DY9U@85010|Pseudonocardiales 201174|Actinobacteria C aconitate hydratase acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_2470_2 857087.Metme_3012 9.43e-54 177.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1XEPZ@135618|Methylococcales 135618|Methylococcales S High frequency lysogenization protein HflD homolog hflD - - ko:K07153 - - - - ko00000 - - - DUF489 k141_2470_3 1387197.AWGA01000024_gene707 2.18e-99 300.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_22182_1 1179778.PMM47T1_00955 7.29e-50 161.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S4NE@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT Type IV pilus response regulator PilH pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_22182_2 287.DR97_3376 5.2e-69 211.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1YFTK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KT Response regulator receiver domain pilG - - ko:K02657,ko:K03413 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_22182_3 90813.JQMT01000001_gene334 6.68e-08 53.5 COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,461NY@72273|Thiotrichales 72273|Thiotrichales U glutamate--cysteine ligase - - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GshA k141_16572_1 713587.THITH_14585 1.05e-137 399.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1WWKJ@135613|Chromatiales 135613|Chromatiales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_15931_1 713587.THITH_00130 4.8e-53 182.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales 135613|Chromatiales U General secretion pathway protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_6112_1 2340.JV46_28890 7.94e-175 507.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_6112_2 1379270.AUXF01000005_gene492 5.91e-05 44.7 COG0146@1|root,COG0146@2|Bacteria,1ZTH4@142182|Gemmatimonadetes 142182|Gemmatimonadetes EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_18697_1 666684.AfiDRAFT_0713 1.79e-54 185.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,3JSJD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cysteine-rich domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_12477_1 371731.Rsw2DRAFT_3183 5.38e-30 124.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,1FBJ6@1060|Rhodobacter 28211|Alphaproteobacteria M Mechanosensitive ion channel kefA - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - DUF3772,MS_channel k141_8286_1 1278309.KB907100_gene2110 3.97e-240 666.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XIXH@135619|Oceanospirillales 135619|Oceanospirillales T HDOD domain - - - - - - - - - - - - EAL,HDOD k141_8286_2 1278309.KB907100_gene2109 1.06e-140 401.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,1XJ9T@135619|Oceanospirillales 135619|Oceanospirillales S membrane transporter protein - - - - - - - - - - - - TauE k141_8286_3 207954.MED92_06966 0.0 1122.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XHCR@135619|Oceanospirillales 135619|Oceanospirillales EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_8286_4 1278309.KB907100_gene2107 6.41e-31 111.0 2E8CB@1|root,332QY@2|Bacteria,1NFXB@1224|Proteobacteria,1SD8G@1236|Gammaproteobacteria,1XMFF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14435_1 349124.Hhal_0679 6.74e-51 177.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1WWXY@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_10344_2 935840.JAEQ01000002_gene3285 2.24e-153 439.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,43HMK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Glutathione S-transferase yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_15953_1 1117319.PSPO_03380 2.37e-24 104.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,2Q0IZ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_8306_1 264201.pc0921 2.64e-29 111.0 COG5622@1|root,COG5622@2|Bacteria,2JGDA@204428|Chlamydiae 204428|Chlamydiae N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_22193_1 713586.KB900536_gene1389 7.5e-69 233.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales 135613|Chromatiales M PFAM LppC - - - ko:K07121 - - - - ko00000 - - - LppC k141_584_1 396588.Tgr7_1400 1.56e-106 330.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_11068_1 754476.Q7A_829 2.05e-91 302.0 COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K10715 ko02020,ko02024,map02020,map02024 M00517 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE8,HATPase_c,HisKA,Hpt,Response_reg k141_10345_1 1046724.KB889926_gene1373 5.18e-149 449.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,465D4@72275|Alteromonadaceae 1236|Gammaproteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII k141_8883_1 1131553.JIBI01000083_gene2407 2.1e-40 138.0 COG1846@1|root,COG1846@2|Bacteria,1P84V@1224|Proteobacteria,2W5SS@28216|Betaproteobacteria,373G0@32003|Nitrosomonadales 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - k141_8883_2 396588.Tgr7_3079 2.5e-26 107.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_3394_1 1278309.KB907099_gene2634 1.15e-267 737.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XHP0@135619|Oceanospirillales 135619|Oceanospirillales L helicase superfamily c-terminal domain - - - - - - - - - - - - DEAD,Helicase_C k141_20755_1 1278309.KB907107_gene1685 6.43e-38 146.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XKA8@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_20755_2 1278309.KB907107_gene1686 9.34e-226 630.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XR0H@135619|Oceanospirillales 135619|Oceanospirillales O Cytochrome c-type biogenesis protein - - - ko:K02200 - - - - ko00000 - - - TPR_19,TPR_2 k141_20755_3 1278309.KB907107_gene1687 1.91e-82 246.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1XKQE@135619|Oceanospirillales 135619|Oceanospirillales P subunit of a heme lyase ccmH - - ko:K02200 - - - - ko00000 - - - CcmH k141_20755_4 1278309.KB907107_gene1688 3.14e-113 326.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1XK8W@135619|Oceanospirillales 135619|Oceanospirillales CO Thiol disulfide interchange protein ccmG - - ko:K02199 - - - - ko00000,ko03110 - - - Redoxin k141_20755_5 1278309.KB907107_gene1689 8.66e-07 49.7 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales 135619|Oceanospirillales O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_8308_1 765913.ThidrDRAFT_4158 1.19e-16 79.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales 135613|Chromatiales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_8308_2 1123393.KB891332_gene2795 3.95e-05 47.4 2AFZN@1|root,3163M@2|Bacteria,1PWSS@1224|Proteobacteria,2WCBE@28216|Betaproteobacteria,1KTD3@119069|Hydrogenophilales 119069|Hydrogenophilales S ATP synthase I chain - - - - - - - - - - - - ATP-synt_I k141_12495_1 1033802.SSPSH_002102 7.22e-11 61.6 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k141_12495_2 1278309.KB907100_gene1837 6.48e-140 397.0 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,1S3KS@1236|Gammaproteobacteria,1XJH0@135619|Oceanospirillales 135619|Oceanospirillales S Cobalt uptake substrate-specific transmembrane region - - - - - - - - - - - - CbiM k141_12495_3 1278309.KB907100_gene1836 3.65e-102 298.0 COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,1S3PE@1236|Gammaproteobacteria,1XJHE@135619|Oceanospirillales 135619|Oceanospirillales T Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain - - - ko:K15012 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg k141_12495_4 1278309.KB907100_gene1835 1.44e-244 679.0 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,1XH8P@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c k141_11070_1 1159870.KB907784_gene3448 0.000302 45.1 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2VGZJ@28216|Betaproteobacteria,3T1TZ@506|Alcaligenaceae 28216|Betaproteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_7545_1 1232683.ADIMK_3860 3.77e-18 81.3 COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,1RQNB@1236|Gammaproteobacteria,466CF@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_7545_2 1232683.ADIMK_3859 0.0 1059.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,464ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B xdhB - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_11712_2 398767.Glov_0045 1.08e-18 90.5 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43S8H@69541|Desulfuromonadales 28221|Deltaproteobacteria T sensor diguanylate cyclase phosphodiesterase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PilJ,Response_reg,dCache_1 k141_2652_1 1278309.KB907100_gene1796 1.27e-159 471.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales 135619|Oceanospirillales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_2652_2 1278309.KB907100_gene1797 1.11e-201 562.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1XHDS@135619|Oceanospirillales 135619|Oceanospirillales K RNA polymerase sigma factor RpoS rpoS - - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_11071_1 396588.Tgr7_2693 5.86e-54 175.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,1WYF1@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8885_1 1120919.AUBI01000003_gene1500 2.18e-06 54.7 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria 28211|Alphaproteobacteria K metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 k141_8309_1 395493.BegalDRAFT_3281 1.32e-51 174.0 COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria 1224|Proteobacteria L dna polymerase iii - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - PAS_4,RNase_T k141_22196_1 349124.Hhal_1916 1.31e-15 79.7 COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_3,HlyD_D23,OEP k141_22196_2 1123514.KB905899_gene842 5.36e-75 246.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_18716_1 1278309.KB907104_gene906 7.62e-152 430.0 COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,1S2CW@1236|Gammaproteobacteria,1XIWZ@135619|Oceanospirillales 135619|Oceanospirillales S Alpha beta hydrolase - - - ko:K01175 - - - - ko00000,ko01000 - - - Abhydrolase_1 k141_18716_2 1278309.KB907104_gene907 3.81e-116 336.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1XIUP@135619|Oceanospirillales 135619|Oceanospirillales O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_13171_1 1288826.MSNKSG1_11972 3.18e-236 649.0 COG0834@1|root,COG0834@2|Bacteria,1RIGN@1224|Proteobacteria,1RR7F@1236|Gammaproteobacteria,4664K@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain pedG - - - - - - - - - - - SBP_bac_3 k141_13171_2 1288826.MSNKSG1_11967 1.8e-187 533.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,4663U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG4993 Glucose dehydrogenase pedH - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 k141_17291_1 1288826.MSNKSG1_12932 5.39e-249 708.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,464KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_20756_1 1131553.JIBI01000046_gene1599 7.77e-39 136.0 COG2010@1|root,COG2010@2|Bacteria,1NE41@1224|Proteobacteria,2WEJ6@28216|Betaproteobacteria,373D7@32003|Nitrosomonadales 28216|Betaproteobacteria C Cytochrome c, class I - - - - - - - - - - - - Cytochrome_CBB3 k141_20756_2 439375.Oant_3156 2.15e-09 58.9 COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,2UC95@28211|Alphaproteobacteria,1J41P@118882|Brucellaceae 28211|Alphaproteobacteria K MerR, DNA binding merR - - ko:K08365 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k141_21521_1 1288826.MSNKSG1_08648 3.77e-259 715.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_21521_2 1288826.MSNKSG1_08653 1.02e-116 339.0 2DR20@1|root,339U3@2|Bacteria,1NI48@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_16595_2 1288826.MSNKSG1_05246 1.05e-99 290.0 COG3418@1|root,COG3418@2|Bacteria,1NGUP@1224|Proteobacteria,1SHTW@1236|Gammaproteobacteria,468Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria N FlgN protein flgN - - ko:K02399 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgN k141_16595_3 1288826.MSNKSG1_05251 4.17e-65 199.0 COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,468Z3@72275|Alteromonadaceae 1236|Gammaproteobacteria KNU COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) flgM - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_16595_4 1288826.MSNKSG1_05256 2.32e-143 407.0 COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,46C3K@72275|Alteromonadaceae 1236|Gammaproteobacteria N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_16595_5 1288826.MSNKSG1_05261 1.12e-213 591.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,465CQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0835 Chemotaxis signal transduction protein cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_16595_6 1288826.MSNKSG1_05266 2.96e-24 97.4 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,4648H@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_22197_1 1144312.PMI09_04874 1.92e-35 124.0 COG2044@1|root,COG2044@2|Bacteria,1RGAZ@1224|Proteobacteria,2UBFX@28211|Alphaproteobacteria,4BEWP@82115|Rhizobiaceae 28211|Alphaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_4798_1 626887.J057_16385 2.25e-101 303.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the class I fructose-bisphosphate aldolase family alf1 - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic k141_13853_1 1288826.MSNKSG1_05546 3.11e-118 349.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,46406@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim k141_13853_2 1288826.MSNKSG1_05551 0.0 1210.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464PG@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K20974 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_13853_3 1288826.MSNKSG1_05556 4.51e-12 64.7 COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,1SEI1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transport system periplasmic component - - - - - - - - - - - - ABC_sub_bind k141_12496_2 572477.Alvin_1014 5.66e-10 56.2 2EGA9@1|root,33A23@2|Bacteria,1NI0T@1224|Proteobacteria,1SH37@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22198_1 1123393.KB891332_gene2814 2.09e-33 130.0 COG2206@1|root,COG2206@2|Bacteria,1MWDU@1224|Proteobacteria,2VIAF@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - HD_5 k141_18067_1 1122201.AUAZ01000023_gene2991 1.15e-127 370.0 COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,1RRV7@1236|Gammaproteobacteria,46AEY@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k141_18067_2 1122201.AUAZ01000023_gene2992 1.84e-185 522.0 COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,1RR46@1236|Gammaproteobacteria,469W6@72275|Alteromonadaceae 1236|Gammaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_18067_3 1122201.AUAZ01000023_gene2993 4.82e-163 459.0 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,1RQ3V@1236|Gammaproteobacteria,469QX@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_18067_4 1122201.AUAZ01000023_gene2994 1.68e-117 341.0 COG2188@1|root,COG2188@2|Bacteria,1Q856@1224|Proteobacteria,1RQ3N@1236|Gammaproteobacteria,46DH7@72275|Alteromonadaceae 1236|Gammaproteobacteria K UTRA phnF - - ko:K02043,ko:K03482 - - - - ko00000,ko03000 - - - GntR,UTRA k141_18067_5 91464.S7335_4978 3.66e-14 69.7 COG3624@1|root,COG3624@2|Bacteria,1G7IP@1117|Cyanobacteria 1117|Cyanobacteria P phosphonate C-P lyase system protein - - 2.7.8.37 ko:K06166 ko00440,map00440 - R10185 RC00005,RC00063 ko00000,ko00001,ko01000 - - - PhnG k141_9575_1 1288826.MSNKSG1_14402 4.8e-204 568.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,463ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_9575_2 1288826.MSNKSG1_14397 0.0 955.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB k141_9575_3 1288826.MSNKSG1_14392 1.53e-173 486.0 COG0834@1|root,COG0834@2|Bacteria,1MZJY@1224|Proteobacteria,1SCZG@1236|Gammaproteobacteria,46BVG@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_9575_4 1288826.MSNKSG1_14387 9.76e-169 471.0 292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,1S44V@1236|Gammaproteobacteria,46BI2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3047) - - - - - - - - - - - - DUF3047 k141_9575_5 1288826.MSNKSG1_14382 5.11e-46 155.0 COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,464D3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain luxR - - - - - - - - - - - GerE,Response_reg k141_7546_1 90814.KL370891_gene1377 3.75e-177 506.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2,Usp k141_7546_2 589865.DaAHT2_1229 2.81e-33 120.0 COG1278@1|root,COG1544@1|root,COG1278@2|Bacteria,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,42TYD@68525|delta/epsilon subdivisions,2WQSG@28221|Deltaproteobacteria,2MNK5@213118|Desulfobacterales 28221|Deltaproteobacteria J Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - CSD,Ribosomal_S30AE k141_21522_1 419610.Mext_4338 8.79e-41 148.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,1JS8C@119045|Methylobacteriaceae 28211|Alphaproteobacteria EGP PFAM General substrate transporter MA20_40020 - - - - - - - - - - - MFS_1,Sugar_tr k141_8310_2 1535422.ND16A_2291 1.38e-63 205.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,2Q6BZ@267889|Colwelliaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_8310_3 713586.KB900536_gene1687 1.64e-10 60.5 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1WW0T@135613|Chromatiales 135613|Chromatiales E PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_18717_1 396588.Tgr7_0024 1.02e-73 233.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1WW02@135613|Chromatiales 135613|Chromatiales GM PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_13854_1 1123279.ATUS01000003_gene441 2.37e-13 69.3 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1J63M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N COG4787 Flagellar basal body rod protein flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_13854_2 1123368.AUIS01000001_gene2092 3.46e-59 190.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,2NCJT@225057|Acidithiobacillales 225057|Acidithiobacillales N Flagella basal body rod protein - - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_587_1 1123393.KB891326_gene36 1.43e-75 234.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2VR0S@28216|Betaproteobacteria,1KSTC@119069|Hydrogenophilales 119069|Hydrogenophilales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k141_7690_1 105559.Nwat_2211 1.66e-31 128.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1WWH5@135613|Chromatiales 135613|Chromatiales N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_11173_1 105559.Nwat_0730 1.59e-94 283.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1WYMH@135613|Chromatiales 135613|Chromatiales P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU k141_12565_1 443152.MDG893_18382 2.97e-73 224.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S4SX@1236|Gammaproteobacteria,467H4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_12565_2 1122194.AUHU01000005_gene868 2.54e-63 204.0 COG4520@1|root,COG4520@2|Bacteria,1RK3Q@1224|Proteobacteria,1S60G@1236|Gammaproteobacteria,467MS@72275|Alteromonadaceae 1236|Gammaproteobacteria M surface antigen - - - - - - - - - - - - - k141_13958_1 1278309.KB907101_gene457 1.2e-115 355.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTVB@1224|Proteobacteria,1RYDJ@1236|Gammaproteobacteria,1XRSZ@135619|Oceanospirillales 135619|Oceanospirillales T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg k141_17437_1 1122197.ATWI01000014_gene45 2.26e-13 70.1 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_17437_2 1278309.KB907101_gene563 7.06e-55 180.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XI8J@135619|Oceanospirillales 135619|Oceanospirillales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k141_16046_1 521719.ATXQ01000001_gene318 5.41e-09 57.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RWYE@1236|Gammaproteobacteria,1YJXE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_16046_2 1122201.AUAZ01000014_gene290 3.86e-30 112.0 COG3449@1|root,COG3449@2|Bacteria 2|Bacteria K DNA topoisomerase (ATP-hydrolyzing) inhibitor activity - - - ko:K13652 - - - - ko00000,ko03000 - - - Cass2,GyrI-like,HTH_18 k141_3499_1 493475.GARC_1352 1.6e-19 84.0 COG3308@1|root,COG3308@2|Bacteria,1N134@1224|Proteobacteria,1S8XA@1236|Gammaproteobacteria,46832@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2069) - - - - - - - - - - - - DUF2069 k141_3499_2 1443113.LC20_04021 1.18e-15 75.5 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,41DXK@629|Yersinia 1236|Gammaproteobacteria J Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_7691_1 132113.XP_003494847.1 6.2e-39 146.0 COG0442@1|root,COG0642@1|root,KOG0519@2759|Eukaryota,KOG2324@2759|Eukaryota,38HAU@33154|Opisthokonta,3BD03@33208|Metazoa,3CSIY@33213|Bilateria,41XHG@6656|Arthropoda,3SGR7@50557|Insecta,46JGQ@7399|Hymenoptera 33208|Metazoa J Anticodon binding domain - - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_4196_1 395493.BegalDRAFT_2094 1.86e-46 171.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4604W@72273|Thiotrichales 72273|Thiotrichales D cell division protein ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_20233_1 1335757.SPICUR_02715 1.87e-25 107.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_19543_1 1453503.AU05_07140 1.11e-48 166.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,1RNY9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E peptidase M24 - - - - - - - - - - - - Creatinase_N,Peptidase_M24 k141_19543_2 1395571.TMS3_0114800 9.01e-37 137.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_11174_2 472759.Nhal_2797 8.05e-39 132.0 COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales 135613|Chromatiales H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_1412_1 1206777.B195_00570 4.62e-06 47.0 2AVGW@1|root,31M96@2|Bacteria,1QJ3Z@1224|Proteobacteria,1TH1C@1236|Gammaproteobacteria,1Z876@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Domain of unknown function (DUF1127) - - - - - - - - - - - - DUF1127 k141_14_1 265072.Mfla_1183 3.97e-68 230.0 COG2204@1|root,COG5001@1|root,COG2204@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KM09@206350|Nitrosomonadales 206350|Nitrosomonadales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,Response_reg k141_13959_1 765910.MARPU_08030 7.74e-56 185.0 COG2138@1|root,COG2138@2|Bacteria,1R8AE@1224|Proteobacteria,1S06H@1236|Gammaproteobacteria,1WVZC@135613|Chromatiales 135613|Chromatiales S PFAM cobalamin (vitamin B12) biosynthesis CbiX - - - - - - - - - - - - CbiX k141_719_2 713586.KB900536_gene167 9e-170 479.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1WX3I@135613|Chromatiales 135613|Chromatiales E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_9075_2 443152.MDG893_02685 1e-44 169.0 COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1T315@1236|Gammaproteobacteria,46AA9@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - AAA_16,GAF,GGDEF,Pkinase k141_12567_1 1049564.TevJSym_bk00180 3.28e-81 246.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1J4G1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 k141_12567_2 653733.Selin_2108 4.25e-08 54.7 COG1030@1|root,COG1030@2|Bacteria 2|Bacteria - - nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_9772_1 1265503.KB905162_gene3509 3.59e-37 141.0 COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1SND8@1236|Gammaproteobacteria,2Q86D@267889|Colwelliaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_9772_2 1038859.AXAU01000008_gene2066 1.45e-09 56.6 COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2UAPG@28211|Alphaproteobacteria,3JYFP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MA20_43515 - - - - - - - - - - - Glyoxalase k141_3500_1 40215.BBOS01000066_gene1422 5.17e-36 134.0 COG0323@1|root,COG0323@2|Bacteria,1P2C7@1224|Proteobacteria,1RZDU@1236|Gammaproteobacteria,3NR57@468|Moraxellaceae 1236|Gammaproteobacteria L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c_3 k141_3500_2 1123373.ATXI01000003_gene1343 4.64e-13 70.1 COG0568@1|root,COG0568@2|Bacteria,2GGUQ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_11175_1 1318628.MARLIPOL_08529 1.67e-33 130.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,465XU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k141_6987_3 1138822.PL11_06245 2.23e-16 82.4 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_10468_1 1085623.GNIT_2137 3.62e-41 143.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,46749@72275|Alteromonadaceae 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4 k141_10468_2 666681.M301_1701 5.79e-45 164.0 COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM EAL domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9 k141_18840_1 1042375.AFPL01000038_gene1545 2.31e-143 409.0 COG4221@1|root,COG4221@2|Bacteria 2|Bacteria IQ oxidoreductase activity - - - - - - - - - - - - adh_short,adh_short_C2 k141_18840_2 1042375.AFPL01000038_gene1546 2.11e-137 393.0 COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,4663B@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 k141_20235_1 1123392.AQWL01000005_gene2880 2.62e-36 136.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - 3.2.1.4 ko:K01179,ko:K21449 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000 1.B.40.2 GH5,GH9 - DUF1929,Laminin_G_3,Metallophos k141_5594_2 351348.Maqu_1336 1.06e-42 139.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,4689P@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_5594_3 1288826.MSNKSG1_05386 1.13e-87 258.0 COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,1SAVX@1236|Gammaproteobacteria,468TW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 k141_5607_2 83406.HDN1F_09050 5.65e-07 51.6 COG2199@1|root,COG3706@2|Bacteria,1R59V@1224|Proteobacteria,1S4YK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg k141_7707_1 1122599.AUGR01000017_gene2904 8.42e-128 399.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1XJGI@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_7707_2 1232683.ADIMK_1148 2.92e-83 255.0 COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,1S2B4@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator vanR - - ko:K11475 - - - - ko00000,ko03000 - - - FCD,GntR k141_9785_1 1278309.KB907103_gene1083 1.6e-100 306.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XHCU@135619|Oceanospirillales 135619|Oceanospirillales V MATE efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_18861_1 472759.Nhal_3855 6.05e-25 94.4 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1WZR6@135613|Chromatiales 135613|Chromatiales S Zinc-finger domain - - - - - - - - - - - - zf-CHCC k141_18861_2 498211.CJA_1368 3.75e-28 123.0 COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1FG3M@10|Cellvibrio 1236|Gammaproteobacteria S Domain of unknown function (DUF3413) - - - ko:K07014 - - - - ko00000 - - - DUF3413,Sulfatase k141_20257_1 545276.KB898732_gene2480 3.35e-106 315.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_15372_1 713586.KB900536_gene1391 9.66e-79 249.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WXBN@135613|Chromatiales 135613|Chromatiales C PFAM FAD linked oxidase domain protein - - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_21635_2 1049564.TevJSym_ac00930 3.93e-93 281.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1J53F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_13284_2 1248760.ANFZ01000006_gene2500 2.08e-32 130.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales 204457|Sphingomonadales V Secretion protein, HlyD - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_13976_1 1109445.AGSX01000017_gene1631 3.99e-41 151.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1YZX4@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind k141_13976_2 1123393.KB891327_gene257 2.56e-118 346.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,1KRBG@119069|Hydrogenophilales 119069|Hydrogenophilales J tRNA synthetases class II core domain (F) pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_18149_1 870187.Thini_1187 8.86e-130 391.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales 72273|Thiotrichales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_16762_1 1288826.MSNKSG1_02258 0.0 1540.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464R3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_16762_2 1288826.MSNKSG1_02263 1.19e-151 428.0 COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,466SC@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0564 Pseudouridylate synthases, 23S RNA-specific truC GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 ko:K06175 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_2 k141_19550_1 999141.GME_05445 1.13e-05 46.6 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMAS@1236|Gammaproteobacteria,1XP7Z@135619|Oceanospirillales 135619|Oceanospirillales S short-chain - - - - - - - - - - - - adh_short k141_19550_2 1278309.KB907101_gene767 3.54e-132 377.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1XKC9@135619|Oceanospirillales 135619|Oceanospirillales S hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_19550_3 1278309.KB907101_gene768 6.85e-200 558.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XIQE@135619|Oceanospirillales 135619|Oceanospirillales OU peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_19550_4 1163617.SCD_n02575 8.37e-79 235.0 2E4PM@1|root,32P93@2|Bacteria,1N4SK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_8398_1 1278309.KB907100_gene1841 5.43e-20 87.4 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XIU6@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_8398_2 1232683.ADIMK_0698 1.11e-119 351.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,467E5@72275|Alteromonadaceae 1236|Gammaproteobacteria P ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_9094_1 998674.ATTE01000001_gene2255 1.01e-53 175.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,460NW@72273|Thiotrichales 72273|Thiotrichales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_9094_2 297246.lpp1326 4.53e-12 65.5 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1SYTB@1236|Gammaproteobacteria,1JC5J@118969|Legionellales 118969|Legionellales S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA k141_20258_1 1288826.MSNKSG1_09133 2.1e-165 471.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,4643J@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_13285_1 391587.KAOT1_01320 9.06e-113 355.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia 976|Bacteroidetes EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k141_26_1 435908.IDSA_01070 1.25e-12 68.2 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,2QFJN@267893|Idiomarinaceae 1236|Gammaproteobacteria F Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_26_2 1538295.JY96_05210 2.78e-07 51.6 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,1KJ7F@119065|unclassified Burkholderiales 28216|Betaproteobacteria H Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_18862_1 1166948.JPZL01000003_gene629 3.87e-22 95.9 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XKPZ@135619|Oceanospirillales 135619|Oceanospirillales C cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 k141_18862_2 398767.Glov_1190 1.59e-29 111.0 COG0053@1|root,COG0053@2|Bacteria,1ND3V@1224|Proteobacteria,431R3@68525|delta/epsilon subdivisions,2WWYS@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_20949_2 1288826.MSNKSG1_14857 8.61e-185 515.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,4647Q@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N k141_20949_3 1288826.MSNKSG1_14852 1.7e-233 641.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,464YS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Coprogen_oxidas k141_7710_1 323848.Nmul_A2329 1.07e-71 226.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2VN04@28216|Betaproteobacteria,372SJ@32003|Nitrosomonadales 28216|Betaproteobacteria G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin k141_15373_1 1042375.AFPL01000038_gene1566 1.48e-57 190.0 COG2199@1|root,COG2199@2|Bacteria,1R4XN@1224|Proteobacteria,1RQ6S@1236|Gammaproteobacteria,46DBM@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_4 k141_8399_1 396588.Tgr7_2694 7.48e-38 141.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales 135613|Chromatiales T PFAM Metal-dependent hydrolase HDOD - - - - - - - - - - - - HDOD k141_9095_1 1479237.JMLY01000001_gene2568 2.47e-83 267.0 COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,1RMGX@1236|Gammaproteobacteria,465E9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2943 Membrane glycosyltransferase mdoH GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 - ko:K03669 - - - - ko00000,ko01000,ko01003,ko02000 4.D.3.1.1 GT2 - Glyco_trans_2_3,Glycos_transf_2 k141_739_1 395493.BegalDRAFT_2373 5.56e-106 335.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,460CJ@72273|Thiotrichales 72273|Thiotrichales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,TPR_1,TPR_2,VWA_2 k141_19551_1 1234364.AMSF01000013_gene683 1.28e-14 71.6 2E0HJ@1|root,32W3D@2|Bacteria,1N10N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_19551_2 1156844.KB891849_gene3534 2.79e-17 80.9 2E9YS@1|root,3344A@2|Bacteria,2IJZ5@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF3592) - - - - - - - - - - - - DUF3592 k141_20259_1 1278309.KB907100_gene2363 2.14e-106 312.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1XH5S@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_9786_1 1056820.KB900674_gene2494 1.5e-100 326.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,2PPFG@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria KLT Protein kinase domain stk1 - 2.7.11.1 ko:K08282,ko:K11916,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02044 - - - FGE-sulfatase,Pkinase k141_20950_1 493475.GARC_0535 3.18e-31 120.0 COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria,4677U@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_16057_1 1124780.ANNU01000030_gene1137 1.36e-43 155.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47JYJ@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) accD5 - - - - - - - - - - - Carboxyl_trans k141_16057_2 761193.Runsl_2368 2.02e-40 143.0 COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,47JJ3@768503|Cytophagia 976|Bacteroidetes S Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core2 k141_19013_2 697282.Mettu_0698 1.66e-156 448.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales 135618|Methylococcales IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_16202_1 472759.Nhal_0847 8.4e-92 275.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1WWM4@135613|Chromatiales 135613|Chromatiales H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 k141_4371_1 693979.Bache_1855 2.72e-72 243.0 COG1033@1|root,COG1033@2|Bacteria,4NKHV@976|Bacteroidetes,2FNS1@200643|Bacteroidia,4AQ58@815|Bacteroidaceae 976|Bacteroidetes S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_9209_2 1116375.VEJY3_23226 2.24e-64 206.0 COG0583@1|root,COG0583@2|Bacteria,1MXR5@1224|Proteobacteria,1SYUU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9908_3 765914.ThisiDRAFT_0937 4.35e-38 133.0 COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1WW9G@135613|Chromatiales 135613|Chromatiales J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_7860_2 765912.Thimo_0714 7.45e-76 232.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_11374_1 1049564.TevJSym_ap00150 6.06e-104 322.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1J55U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Multicopper oxidase pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_18302_1 1278309.KB907107_gene1704 1.17e-65 218.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHWH@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis protein histidine kinase and related - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_18302_2 1278309.KB907107_gene1705 4.33e-116 341.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1XJNC@135619|Oceanospirillales 135619|Oceanospirillales NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) cheZ - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_18302_3 1278309.KB907107_gene1706 2.99e-78 233.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1XJKC@135619|Oceanospirillales 135619|Oceanospirillales T Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_18302_4 1278309.KB907107_gene1707 3.31e-149 422.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1XIKW@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_18302_5 1278309.KB907107_gene1708 1.04e-154 439.0 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1XH4Y@135619|Oceanospirillales 135619|Oceanospirillales D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - ko:K04562 - - - - ko00000,ko02035 - - - ParA k141_18302_6 1278309.KB907107_gene1709 6.02e-63 206.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1XIUW@135619|Oceanospirillales 135619|Oceanospirillales N SRP54-type protein, GTPase domain - - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_10657_1 1288826.MSNKSG1_08793 6.23e-54 177.0 COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria,4668D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chain length determinant protein wzz - - - - - - - - - - - GNVR,Wzz k141_10657_2 1288826.MSNKSG1_08798 1.16e-163 481.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,4662T@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_21765_1 1122207.MUS1_14855 2.68e-83 248.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XJM2@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k141_21765_2 1122214.AQWH01000004_gene1079 1.47e-64 216.0 COG0657@1|root,COG1309@1|root,COG0657@2|Bacteria,COG1309@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,2PKVT@255475|Aurantimonadaceae 28211|Alphaproteobacteria K alpha/beta hydrolase fold - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 k141_21765_3 1121403.AUCV01000002_gene604 3.67e-181 511.0 COG1638@1|root,COG1638@2|Bacteria,1NJX4@1224|Proteobacteria,42QE0@68525|delta/epsilon subdivisions,2WP8A@28221|Deltaproteobacteria,2MNDU@213118|Desulfobacterales 28221|Deltaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_12734_1 1341181.FLJC2902T_26920 4.34e-09 62.8 COG2202@1|root,COG4251@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,4NI5R@976|Bacteroidetes,1IKW5@117743|Flavobacteriia,2P01K@237|Flavobacterium 976|Bacteroidetes T Four helix bundle sensory module for signal transduction - - - - - - - - - - - - 4HB_MCP_1,CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_9 k141_8551_1 644076.SCH4B_4604 3.74e-37 135.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,4NA3Z@97050|Ruegeria 28211|Alphaproteobacteria H Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_8551_2 89187.ISM_14755 2.18e-36 136.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,46NA2@74030|Roseovarius 28211|Alphaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_159_2 1232683.ADIMK_0711 1.4e-124 360.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,464P9@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ompR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_159_3 1232683.ADIMK_0710 2.37e-164 478.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,4640Q@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_159_5 1348114.OM33_21730 9.54e-56 177.0 COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria,2Q2WF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - - - - - - - - - - - k141_159_6 1122599.AUGR01000010_gene1060 8.26e-75 228.0 COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,1RZBH@1236|Gammaproteobacteria,1XJWF@135619|Oceanospirillales 135619|Oceanospirillales K Repressor involved in choline regulation of the bet genes betI - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N k141_21151_1 580332.Slit_2551 1.04e-108 326.0 COG1156@1|root,COG1156@2|Bacteria,1QUQE@1224|Proteobacteria 1224|Proteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - ko:K02118 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_ab k141_19014_2 643867.Ftrac_0570 1.25e-23 98.6 COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_20414_1 765912.Thimo_2945 7.24e-56 191.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,1WWYA@135613|Chromatiales 135613|Chromatiales CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_14844_1 95619.PM1_0201455 3.86e-44 163.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria 1236|Gammaproteobacteria M penicillin-binding protein 1A mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_14844_2 187272.Mlg_2753 2.26e-54 179.0 COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X2NE@135613|Chromatiales 135613|Chromatiales S mRNA catabolic process - - - - - - - - - - - - - k141_14844_3 631362.Thi970DRAFT_01752 4.04e-25 103.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1WVWD@135613|Chromatiales 135613|Chromatiales C PFAM malic - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_4372_1 765911.Thivi_2743 1.71e-73 244.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_5795_1 2340.JV46_08870 1.79e-103 331.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1J7JF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C k141_7861_1 357804.Ping_2416 2.04e-14 77.0 COG0583@1|root,COG0583@2|Bacteria,1MW4Y@1224|Proteobacteria,1RNJT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_17604_1 1337093.MBE-LCI_3309 4.05e-25 100.0 COG1940@1|root,COG1940@2|Bacteria,1QSSV@1224|Proteobacteria,2VGK9@28211|Alphaproteobacteria 28211|Alphaproteobacteria GK ROK family - - - - - - - - - - - - ROK k141_17604_2 1337093.MBE-LCI_3308 7.68e-98 295.0 COG1879@1|root,COG1879@2|Bacteria,1RDXP@1224|Proteobacteria,2TV3C@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_16907_1 388739.RSK20926_15466 2.2e-116 363.0 2F01Z@1|root,33T5S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_13442_2 187272.Mlg_1397 1.73e-75 237.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,1WX44@135613|Chromatiales 135613|Chromatiales N PFAM MotA TolQ ExbB proton channel - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_13442_3 290402.Cbei_4830 4.52e-23 100.0 COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,247RE@186801|Clostridia,36DJJ@31979|Clostridiaceae 186801|Clostridia N PFAM OmpA MotB domain protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_9909_1 1268239.PALB_29870 2.4e-11 63.5 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,2Q1GT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Carbon-nitrogen hydrolase aguB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_9909_2 351348.Maqu_1750 1.07e-58 192.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,465QS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph k141_15557_1 1410620.SHLA_8c000280 9.39e-81 247.0 COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,2TRQ0@28211|Alphaproteobacteria,4BFF8@82115|Rhizobiaceae 28211|Alphaproteobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 k141_5035_1 1288826.MSNKSG1_05471 1.02e-182 519.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,465MD@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1070 Sugar (pentulose and hexulose) kinases ygcE - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_11375_1 694427.Palpr_0909 5.53e-31 114.0 COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,2FQ64@200643|Bacteroidia,22Y8Z@171551|Porphyromonadaceae 976|Bacteroidetes S Bacterial transferase hexapeptide (six repeats) vat_2 - - ko:K18234 - - - - ko00000,ko01000,ko01504 - - - Hexapep k141_8552_1 1279017.AQYJ01000029_gene3826 5.67e-47 158.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,466JR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_8552_2 1168067.JAGP01000001_gene2020 2.37e-42 142.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,462CZ@72273|Thiotrichales 72273|Thiotrichales O Redoxin - - - - - - - - - - - - AhpC-TSA k141_21152_2 765912.Thimo_1331 2.01e-60 192.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1WY8B@135613|Chromatiales 135613|Chromatiales S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_12033_1 521719.ATXQ01000006_gene1351 1.61e-74 234.0 COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1YH9F@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria CF Dihydroorotate dehydrogenase - - 1.3.1.1,1.3.98.1 ko:K00226,ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046,M00051 R00977,R01414,R01867,R11026 RC00051,RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,Fer4_21 k141_17605_1 1163617.SCD_n01562 6.6e-50 162.0 COG0460@1|root,COG0460@2|Bacteria,1NFDV@1224|Proteobacteria,2WHES@28216|Betaproteobacteria 28216|Betaproteobacteria E Homoserine dehydrogenase, NAD binding domain - - - - - - - - - - - - NAD_binding_3 k141_20415_2 1415779.JOMH01000001_gene1600 2.43e-17 80.9 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1X733@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 k141_13443_1 1121013.P873_02810 1.42e-71 236.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X3FJ@135614|Xanthomonadales 135614|Xanthomonadales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_1576_2 1278309.KB907102_gene39 1.63e-155 443.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1XHYN@135619|Oceanospirillales 135619|Oceanospirillales D Reduces the stability of FtsZ polymers in the presence of ATP zapE - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_3676_1 287.DR97_5628 5.73e-81 266.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1YD8C@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M POTRA domain TamA domain 1 ytfM GO:0002790,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_3676_2 247634.GPB2148_742 4.28e-07 62.4 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1J546@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ytfN GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_16204_1 314232.SKA53_08266 1.08e-122 358.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria,2P7X9@245186|Loktanella 28211|Alphaproteobacteria U Binding-protein-dependent transport system inner membrane component yejB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_16204_2 441620.Mpop_2443 0.000569 42.4 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,1JR6A@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component yejE GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k141_18303_1 1064535.MELS_0833 6.33e-13 79.7 COG1484@1|root,COG1484@2|Bacteria,1UJTS@1239|Firmicutes,4H1Y1@909932|Negativicutes 909932|Negativicutes L DNA-dependent DNA replication - - - - - - - - - - - - - k141_21768_1 311403.Arad_7578 2e-50 181.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B880@82115|Rhizobiaceae 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9,Response_reg k141_5036_1 886377.Murru_2712 3.62e-45 152.0 COG0664@1|root,COG0664@2|Bacteria,4NKXK@976|Bacteroidetes,1I0MZ@117743|Flavobacteriia 976|Bacteroidetes T Cyclic nucleotide-binding domain - - - - - - - - - - - - cNMP_binding k141_4373_2 1049564.TevJSym_aa01730 1.01e-21 90.5 2E189@1|root,32WNT@2|Bacteria,1N4GY@1224|Proteobacteria,1SBNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_160_2 1177179.A11A3_11117 1.36e-20 87.0 28PNW@1|root,2ZCBD@2|Bacteria,1RIQY@1224|Proteobacteria,1SKNQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16909_2 95619.PM1_0215315 6.27e-42 143.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Peptidyl-prolyl cis-trans slyD GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_12737_1 1278309.KB907100_gene1994 6.86e-83 265.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XHZK@135619|Oceanospirillales 135619|Oceanospirillales U Type II and III secretion system protein pilQ - - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_21769_1 243924.LT42_14530 0.00041 42.4 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_21769_2 1123400.KB904769_gene2898 1.42e-19 84.7 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_20451_2 1122236.KB905141_gene947 6.69e-34 128.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,2KKYX@206350|Nitrosomonadales 206350|Nitrosomonadales CI TIGRFAM oxaloacetate decarboxylase alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_14146_1 1227739.Hsw_0004 3.17e-22 94.7 COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,47JSB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldJ gldJ - - - - - - - - - - - FGE-sulfatase k141_14146_2 1150600.ADIARSV_1806 1.17e-28 111.0 COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Phosphoribosyl transferase domain comF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Pribosyltran k141_18317_1 580332.Slit_0810 2.35e-33 119.0 2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,2VX71@28216|Betaproteobacteria,44WGB@713636|Nitrosomonadales 28216|Betaproteobacteria S Nitrogen fixation protein NifW nifW - - ko:K02595 - - - - ko00000 - - - NifW k141_18317_2 395493.BegalDRAFT_0559 3.25e-43 149.0 COG0457@1|root,COG0457@2|Bacteria,1R714@1224|Proteobacteria,1SA9Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_18317_3 322710.Avin_01650 1.94e-26 105.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_11390_1 1232683.ADIMK_4172 1.64e-181 520.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4656N@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_5825_1 1278309.KB907106_gene1293 3.56e-173 492.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales 135619|Oceanospirillales CH hydroxylase ubiF - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_6454_1 1288826.MSNKSG1_05521 2.9e-64 201.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,466QM@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein J gspJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_6454_2 1288826.MSNKSG1_05526 6.22e-217 600.0 COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,1S5US@1236|Gammaproteobacteria,46CQU@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3156 Type II secretory pathway, component PulK xcpX - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_6454_3 1288826.MSNKSG1_05531 4.68e-51 172.0 COG3297@1|root,COG3297@2|Bacteria,1N3RU@1224|Proteobacteria,1T05Z@1236|Gammaproteobacteria,46D09@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_3696_1 998674.ATTE01000001_gene4379 4.81e-76 241.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,45ZYW@72273|Thiotrichales 72273|Thiotrichales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_16926_1 1232683.ADIMK_0308 4.51e-183 513.0 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,1RY4A@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Lactoylglutathione lyase and related lyases xylE - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase k141_18327_1 765911.Thivi_1973 3.54e-91 288.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales 135613|Chromatiales U sulphate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_6461_1 545264.KB898746_gene838 8.67e-74 248.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_21809_1 666685.R2APBS1_0139 3.47e-88 275.0 COG5010@1|root,COG5010@2|Bacteria,1R1F0@1224|Proteobacteria,1T502@1236|Gammaproteobacteria,1XDAD@135614|Xanthomonadales 135614|Xanthomonadales U Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 k141_895_1 2340.JV46_13540 3.34e-11 62.8 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1J589@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_895_2 765914.ThisiDRAFT_0967 2.68e-34 120.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1WZ1D@135613|Chromatiales 135613|Chromatiales S solute sodium symporter, small subunit - - - - - - - - - - - - DUF4212 k141_895_3 85643.Tmz1t_2583 7.27e-14 71.6 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,2KVCU@206389|Rhodocyclales 206389|Rhodocyclales T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_14153_1 396588.Tgr7_0707 9.61e-190 543.0 COG3408@1|root,COG3408@2|Bacteria,1R3W7@1224|Proteobacteria,1RVZH@1236|Gammaproteobacteria,1X040@135613|Chromatiales 135613|Chromatiales G Alkaline and neutral invertase - - - - - - - - - - - - Glyco_hydro_100 k141_14153_3 472759.Nhal_3942 7.33e-86 266.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1WXVN@135613|Chromatiales 135613|Chromatiales G PfkB domain protein - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_14153_4 653733.Selin_2400 2.69e-48 171.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria 2|Bacteria Q phosphatase activity sps GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246,3.1.3.24,3.1.3.79 ko:K00696,ko:K07024,ko:K13058,ko:K13086 ko00500,ko01100,map00500,map01100 - R00766,R00805,R06211,R08947,R08982 RC00005,RC00017,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_12071_2 713586.KB900536_gene2042 4.9e-165 467.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales 135613|Chromatiales C PFAM Phosphoribulokinase uridine kinase - - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_12071_3 622637.KE124774_gene1995 2.69e-07 51.2 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,36X48@31993|Methylocystaceae 28211|Alphaproteobacteria GK ROK family - - 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK k141_21178_1 1288826.MSNKSG1_00526 9.93e-150 436.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_21178_2 1121403.AUCV01000038_gene4226 5.64e-13 67.8 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria 1224|Proteobacteria C atp synthase - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_19054_2 216595.PFLU_2981 2.31e-60 195.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RZH1@1236|Gammaproteobacteria,1YRGM@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k141_5065_2 1101195.Meth11DRAFT_2037 4.82e-58 192.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KNQP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM Protein phosphatase - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,SpoIIE k141_5065_3 1479237.JMLY01000001_gene1661 1.8e-25 106.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,465TI@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT COG0515 Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_6462_1 1458427.BAWN01000020_gene1242 7.39e-77 240.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,4ABQ6@80864|Comamonadaceae 28216|Betaproteobacteria E Belongs to the DegT DnrJ EryC1 family wlbC - 2.6.1.98 ko:K13017 ko00520,map00520 - R10141 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 k141_9224_1 1288826.MSNKSG1_06128 4.09e-162 468.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,465RH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_896_1 1279009.ADICEAN_02048 9.77e-82 257.0 COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,47KFQ@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase 4-like - - - ko:K13004 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 k141_12772_1 472759.Nhal_3891 4.29e-131 383.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV pilus assembly protein PilM - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_12772_2 323261.Noc_0246 5.08e-34 131.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_2267_1 1122599.AUGR01000006_gene3840 3.2e-128 380.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XNBS@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_2267_2 1122599.AUGR01000006_gene3839 1.33e-180 508.0 COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,1XN94@135619|Oceanospirillales 135619|Oceanospirillales EM Dihydrodipicolinate synthetase family - - - - - - - - - - - - DHDPS k141_2267_3 1122599.AUGR01000006_gene3835 5.65e-202 563.0 COG0583@1|root,COG0583@2|Bacteria,1MW8C@1224|Proteobacteria,1S0C4@1236|Gammaproteobacteria,1XHF1@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_2267_4 1278309.KB907099_gene2671 1.54e-146 420.0 COG4977@1|root,COG4977@2|Bacteria,1RC9C@1224|Proteobacteria,1RYDT@1236|Gammaproteobacteria,1XJA4@135619|Oceanospirillales 135619|Oceanospirillales K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_7885_1 1288826.MSNKSG1_06188 9.7e-92 269.0 COG2062@1|root,COG2062@2|Bacteria,1NH0V@1224|Proteobacteria,1SJ8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_7885_2 1288826.MSNKSG1_06193 8.42e-239 658.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,464Z9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - iJN746.PP_4169,iSFV_1184.SFV_3923 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_7885_3 1288826.MSNKSG1_06198 5.16e-108 311.0 COG1366@1|root,COG1366@2|Bacteria,1RIIT@1224|Proteobacteria,1S713@1236|Gammaproteobacteria,4681P@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - - - - - - - - - - STAS,STAS_2 k141_17659_3 443152.MDG893_07660 4.52e-176 502.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,4641R@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_11403_1 1278309.KB907100_gene1880 8.16e-151 433.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XI9W@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_11403_2 1278309.KB907100_gene1881 1.04e-224 634.0 28JUZ@1|root,2Z9JZ@2|Bacteria,1R8TM@1224|Proteobacteria,1RNER@1236|Gammaproteobacteria,1XIAG@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11403_3 1278309.KB907100_gene1882 9.73e-145 412.0 COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1XIIA@135619|Oceanospirillales 135619|Oceanospirillales S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE k141_11403_4 1278309.KB907100_gene1883 1.38e-101 299.0 COG1280@1|root,COG1280@2|Bacteria,1RB7U@1224|Proteobacteria,1S2JQ@1236|Gammaproteobacteria,1XRGI@135619|Oceanospirillales 135619|Oceanospirillales E LysE type translocator - - - - - - - - - - - - LysE k141_11403_5 1122211.JMLW01000007_gene66 3.33e-26 116.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XHNA@135619|Oceanospirillales 135619|Oceanospirillales T Methyl-accepting chemotaxis - - - - - - - - - - - - HAMP,MCPsignal k141_13475_1 1278309.KB907109_gene3276 2.32e-270 756.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1XHRA@135619|Oceanospirillales 135619|Oceanospirillales P von Willebrand factor (vWF) type A domain - - - ko:K02448 - - R00294 RC02794 ko00000 3.D.4.10 - - VWA k141_7190_1 292415.Tbd_0282 1.91e-48 174.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,1KSI5@119069|Hydrogenophilales 119069|Hydrogenophilales M G-rich domain on putative tyrosine kinase - - - - - - - - - - - - GNVR k141_206_1 1232683.ADIMK_0538 2.61e-47 165.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,464BS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_206_2 1278309.KB907110_gene3224 3.48e-47 152.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1XKZS@135619|Oceanospirillales 135619|Oceanospirillales S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 k141_9249_2 1492922.GY26_09390 8.91e-71 217.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1J67K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_9249_3 666681.M301_0262 0.000289 43.5 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2WFCK@28216|Betaproteobacteria,2KM25@206350|Nitrosomonadales 206350|Nitrosomonadales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_7917_2 1442599.JAAN01000024_gene1841 9.57e-59 201.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1X49W@135614|Xanthomonadales 135614|Xanthomonadales S mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth uup - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_18356_1 713587.THITH_15735 1.93e-54 188.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1WWBM@135613|Chromatiales 135613|Chromatiales E Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N k141_14175_1 1288826.MSNKSG1_10373 3.75e-153 431.0 COG2304@1|root,COG2304@2|Bacteria,1RA4S@1224|Proteobacteria,1RZNI@1236|Gammaproteobacteria,4678X@72275|Alteromonadaceae 1236|Gammaproteobacteria S oxidoreductase activity - - - - - - - - - - - - - k141_14175_2 1318628.MARLIPOL_02720 5.09e-51 167.0 2F7U0@1|root,34084@2|Bacteria,1NZJ4@1224|Proteobacteria 1318628.MARLIPOL_02720|- - - - - - - - - - - - - - - - k141_14175_3 1318628.MARLIPOL_02715 7.13e-92 276.0 2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14175_4 1288826.MSNKSG1_10378 1.45e-90 266.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,4678Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S Yqey-like protein lporfX - - ko:K09117 - - - - ko00000 - - - YqeY k141_14175_5 1288826.MSNKSG1_10383 4.67e-295 814.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria 1224|Proteobacteria NT Methyl-accepting chemotaxis protein VPA0562 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_19726_1 992406.RIA_0275 4.96e-25 102.0 COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1HWRY@117743|Flavobacteriia 976|Bacteroidetes E prephenate dehydrogenase tyrA - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH k141_19726_2 326423.RBAM_034880 3.73e-09 58.9 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZEPP@1386|Bacillus 91061|Bacilli E Aminotransferase class I and II ywfG GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 - ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 M00034,M00787 R07396,R11068 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_14887_2 1443113.LC20_03583 8.89e-05 47.8 COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,1S44A@1236|Gammaproteobacteria,41FZX@629|Yersinia 1236|Gammaproteobacteria F Belongs to the Nudix hydrolase family rppH_2 - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX k141_13476_1 1069080.KB913028_gene1075 1.26e-19 91.7 COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4H2CH@909932|Negativicutes 909932|Negativicutes T domain protein - - - - - - - - - - - - EAL,HDOD k141_19083_1 472759.Nhal_2748 5.91e-143 422.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_12095_1 765913.ThidrDRAFT_2339 1.51e-89 280.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_2278_1 1278309.KB907102_gene217 7.78e-63 197.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,1XMHJ@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR_2 k141_2278_3 1122599.AUGR01000009_gene2283 4.75e-108 313.0 COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria,1XR24@135619|Oceanospirillales 135619|Oceanospirillales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_2278_4 1278309.KB907102_gene218 2.54e-180 509.0 COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,1T2BY@1236|Gammaproteobacteria,1XKMM@135619|Oceanospirillales 135619|Oceanospirillales T Ion transport protein - - - - - - - - - - - - Ion_trans k141_2278_6 1278309.KB907102_gene220 1.13e-93 276.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1XJZK@135619|Oceanospirillales 135619|Oceanospirillales S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - Molydop_binding,gag-asp_proteas k141_2278_7 1278309.KB907102_gene221 1.31e-255 706.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,1RR20@1236|Gammaproteobacteria,1XIS9@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 k141_2278_8 290398.Csal_2059 8.88e-27 107.0 COG3637@1|root,COG3637@2|Bacteria,1RJMJ@1224|Proteobacteria,1S7PC@1236|Gammaproteobacteria,1XQHX@135619|Oceanospirillales 135619|Oceanospirillales M OmpA-like transmembrane domain - - - - - - - - - - - - OMP_b-brl,OmpA_membrane k141_2278_9 1278309.KB907102_gene227 2.04e-268 745.0 COG1639@1|root,COG2203@1|root,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria,1XKNU@135619|Oceanospirillales 135619|Oceanospirillales T HDOD domain - - - - - - - - - - - - HDOD k141_4431_1 398767.Glov_0141 1.08e-37 133.0 2E92A@1|root,333BE@2|Bacteria,1N8BM@1224|Proteobacteria,4311M@68525|delta/epsilon subdivisions 1224|Proteobacteria - - - - - - - - - - - - - - - k141_17660_1 666685.R2APBS1_0141 1.74e-67 226.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1X3S1@135614|Xanthomonadales 135614|Xanthomonadales H receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_21839_1 1318628.MARLIPOL_15477 5.14e-13 68.9 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,465QR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - HDOD,tRNA_edit k141_21839_2 1288826.MSNKSG1_17416 0.0 1319.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_21839_3 1288826.MSNKSG1_17411 1.99e-212 588.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,46628@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_21839_4 1288826.MSNKSG1_17406 4.74e-25 100.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,4673H@72275|Alteromonadaceae 1236|Gammaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_1628_1 1278309.KB907109_gene3244 6.1e-97 285.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1XKMI@135619|Oceanospirillales 135619|Oceanospirillales CO Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA,Redoxin k141_14176_1 1123400.KB904770_gene2725 3.31e-28 112.0 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,462UE@72273|Thiotrichales 72273|Thiotrichales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_7191_1 90814.KL370892_gene2250 1.28e-126 370.0 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales 72273|Thiotrichales O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_7191_2 396588.Tgr7_0092 3.6e-22 92.8 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1WYV2@135613|Chromatiales 135613|Chromatiales O Thiol disulfide interchange protein - - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA k141_16230_1 929558.SMGD1_2070 7.26e-41 142.0 arCOG05203@1|root,303AI@2|Bacteria,1NZAP@1224|Proteobacteria,430QT@68525|delta/epsilon subdivisions,2YS4S@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria - - - - - - - - - - - - - - - k141_208_1 857087.Metme_3892 2.64e-97 296.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XEG7@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_3024_1 1288826.MSNKSG1_01533 1.85e-196 554.0 COG1653@1|root,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,1RSBF@1236|Gammaproteobacteria,46D56@72275|Alteromonadaceae 1236|Gammaproteobacteria G Domain of unknown function (DUF4397) - - - - - - - - - - - - DUF4397 k141_3024_3 1288826.MSNKSG1_01523 2.22e-182 507.0 COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RRE1@1236|Gammaproteobacteria,4644A@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) HA62_15005 - - - - - - - - - - - adh_short_C2 k141_3024_4 1288826.MSNKSG1_01518 1.02e-160 450.0 COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,1S3H1@1236|Gammaproteobacteria,46DGI@72275|Alteromonadaceae 1236|Gammaproteobacteria G phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 k141_3024_5 1288826.MSNKSG1_01513 1.77e-260 713.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,464Z3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k141_3024_6 1288826.MSNKSG1_01508 3.86e-196 543.0 COG0300@1|root,COG0300@2|Bacteria,1QU6Z@1224|Proteobacteria,1T1P9@1236|Gammaproteobacteria,46ACN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_3024_7 1288826.MSNKSG1_01503 1.37e-69 220.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,464P2@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases HA62_10695 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_19084_1 870187.Thini_2553 1.71e-32 124.0 COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801 NTP_transf_3 k141_388_1 640081.Dsui_0506 3.26e-05 47.8 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - Arm-DNA-bind_3,EAL,GAF_2,GGDEF,PAS_3,PAS_4 k141_5250_1 1201293.AKXQ01000020_gene3060 5.14e-65 201.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09966 - - - - ko00000 - - - DUF2237 k141_5250_2 644801.Psest_2480 6.39e-05 47.4 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z10B@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis protein VPA0491 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_17813_1 1095769.CAHF01000022_gene324 7.33e-98 308.0 COG1716@1|root,COG2203@1|root,COG2206@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,476NW@75682|Oxalobacteraceae 28216|Betaproteobacteria T HD domain - - 3.1.4.17 ko:K01120 ko00230,map00230 - R00191,R01234 RC00296 ko00000,ko00001,ko01000 - - - FHA,GAF,HD,HD_5 k141_8723_1 1454007.JAUG01000034_gene3834 2.4e-105 317.0 COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1INV1@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_3849_1 1237149.C900_02657 1.03e-55 177.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - k141_10108_1 1278309.KB907101_gene711 4.02e-182 525.0 COG3968@1|root,COG3968@2|Bacteria,1QDHB@1224|Proteobacteria,1RS3B@1236|Gammaproteobacteria,1XNV6@135619|Oceanospirillales 135619|Oceanospirillales S Glutamine synthetase type III N terminal - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C k141_10108_2 631362.Thi970DRAFT_04555 1.61e-18 87.4 28PZQ@1|root,2ZCIX@2|Bacteria,1RA7M@1224|Proteobacteria,1S25R@1236|Gammaproteobacteria,1WY1B@135613|Chromatiales 135613|Chromatiales S EF hand - - - - - - - - - - - - EF-hand_5 k141_12955_1 395493.BegalDRAFT_2300 5.86e-104 336.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales 72273|Thiotrichales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_17081_1 477228.YO5_00380 8.94e-51 181.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1Z1NQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O COG0464 ATPases of the AAA class - - - - - - - - - - - - AAA k141_389_1 204773.HEAR1400 2.91e-73 228.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,472IY@75682|Oxalobacteraceae 28216|Betaproteobacteria L TatD related DNase ycfH - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_17814_1 765911.Thivi_0235 3.07e-21 94.7 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1WW1M@135613|Chromatiales 135613|Chromatiales S ErfK YbiS YcfS YnhG family protein - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_12254_1 1042209.HK44_026005 1.36e-45 172.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YQ01@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_12254_2 1278309.KB907103_gene1160 3.01e-151 428.0 COG3221@1|root,COG3221@2|Bacteria,1NAHN@1224|Proteobacteria,1RP4A@1236|Gammaproteobacteria,1XHVY@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - - - - - - - - - - Phosphonate-bd k141_12254_3 1278309.KB907103_gene1159 4.12e-97 283.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJP3@135619|Oceanospirillales 135619|Oceanospirillales NT Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - PAS_3 k141_12254_4 1278309.KB907103_gene1158 2.04e-73 221.0 COG2018@1|root,COG2018@2|Bacteria,1RIQC@1224|Proteobacteria,1S65Z@1236|Gammaproteobacteria,1XJVQ@135619|Oceanospirillales 135619|Oceanospirillales S Roadblock/LC7 domain - - - - - - - - - - - - Robl_LC7 k141_12254_5 1278309.KB907103_gene1157 3.81e-63 198.0 2AHZA@1|root,318CM@2|Bacteria,1RHH8@1224|Proteobacteria,1S827@1236|Gammaproteobacteria,1XJVY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16367_1 1026882.MAMP_01319 8.45e-81 248.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,4606Q@72273|Thiotrichales 72273|Thiotrichales L Exodeoxyribonuclease III xth xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_13621_1 768671.ThimaDRAFT_2363 1.85e-96 299.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_5251_1 1117647.M5M_18165 3.63e-37 131.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_5251_2 1121935.AQXX01000142_gene2326 7.28e-69 227.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9380_1 929558.SMGD1_1814 2.12e-79 257.0 COG5001@1|root,COG5001@2|Bacteria,1NQMR@1224|Proteobacteria,42Z0X@68525|delta/epsilon subdivisions,2YRBN@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_4575_1 396588.Tgr7_0356 6.51e-160 462.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_8112_1 1278309.KB907101_gene300 2.84e-44 145.0 COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XKIR@135619|Oceanospirillales 135619|Oceanospirillales J Translation initiation factor - - - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 k141_8112_2 1278309.KB907101_gene301 2.81e-64 207.0 COG3577@1|root,COG3577@2|Bacteria,1RIR3@1224|Proteobacteria,1S8KD@1236|Gammaproteobacteria,1XKMR@135619|Oceanospirillales 135619|Oceanospirillales S gag-polyprotein putative aspartyl protease - - - - - - - - - - - - Asp_protease_2 k141_8112_3 1278309.KB907101_gene302 2.18e-218 603.0 COG0685@1|root,COG0685@2|Bacteria,1QGEE@1224|Proteobacteria,1RSEG@1236|Gammaproteobacteria,1XII7@135619|Oceanospirillales 135619|Oceanospirillales E Methylenetetrahydrofolate reductase - - - - - - - - - - - - MTHFR k141_8112_4 1278309.KB907101_gene303 4.6e-51 166.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,1S9CC@1236|Gammaproteobacteria,1XJZZ@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 k141_17815_1 1168034.FH5T_15130 4.21e-52 181.0 COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,2G37X@200643|Bacteroidia 976|Bacteroidetes E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 k141_14997_1 1288826.MSNKSG1_13862 6.08e-142 412.0 COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetyl-CoA hydrolase scpC GO:0003674,GO:0003824,GO:0003986,GO:0006082,GO:0006083,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008410,GO:0008775,GO:0009987,GO:0016289,GO:0016740,GO:0016782,GO:0016787,GO:0016788,GO:0016790,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043821,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0071704 2.8.3.18 ko:K18118,ko:K22214 ko00020,ko00620,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00640,map00650,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R10343,R11773 RC00012,RC00014 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_3040,iECSE_1348.ECSE_3182,iECW_1372.ECW_m3175,iEKO11_1354.EKO11_0812,iWFL_1372.ECW_m3175 AcetylCoA_hyd_C,AcetylCoA_hydro k141_14997_2 1288826.MSNKSG1_13857 1.35e-127 365.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,466UP@72275|Alteromonadaceae 1236|Gammaproteobacteria U UPF0056 membrane protein ychE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC k141_14997_3 1288826.MSNKSG1_13852 8.92e-134 379.0 COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,1S2MT@1236|Gammaproteobacteria,46736@72275|Alteromonadaceae 1236|Gammaproteobacteria P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides chaC - - ko:K07232 - - - - ko00000 - - - ChaC k141_13622_1 768671.ThimaDRAFT_3082 5.27e-81 253.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_2452_1 1288826.MSNKSG1_00496 5.1e-76 238.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,465WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_2452_2 1288826.MSNKSG1_00491 1.01e-54 171.0 COG0695@1|root,COG0695@2|Bacteria,1RGZ7@1224|Proteobacteria,1S5ZP@1236|Gammaproteobacteria,468P1@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0695 Glutaredoxin and related proteins grxA - - ko:K03674 - - - - ko00000,ko03110 - - iAF1260.b0849,iB21_1397.B21_00860,iBWG_1329.BWG_0702,iEC55989_1330.EC55989_0894,iECBD_1354.ECBD_2745,iECB_1328.ECB_00854,iECDH10B_1368.ECDH10B_0919,iECDH1ME8569_1439.ECDH1ME8569_0801,iECD_1391.ECD_00854,iECO111_1330.ECO111_0918,iECO26_1355.ECO26_0976,iECSE_1348.ECSE_0907,iECW_1372.ECW_m0957,iEKO11_1354.EKO11_2987,iETEC_1333.ETEC_0916,iEcDH1_1363.EcDH1_2793,iEcE24377_1341.EcE24377A_0921,iJO1366.b0849,iSBO_1134.SBO_0783,iSFV_1184.SFV_0834,iSF_1195.SF0802,iSFxv_1172.SFxv_0871,iSSON_1240.SSON_0834,iS_1188.S0845,iSbBS512_1146.SbBS512_E2483,iWFL_1372.ECW_m0957,iY75_1357.Y75_RS04415 Glutaredoxin k141_2452_3 1288826.MSNKSG1_00486 2.86e-105 303.0 COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1S69A@1236|Gammaproteobacteria,46808@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yqaA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_2452_4 1288826.MSNKSG1_00481 0.0 923.0 COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,1RYAY@1236|Gammaproteobacteria,464YP@72275|Alteromonadaceae 1236|Gammaproteobacteria S unusual protein kinase - - - - - - - - - - - - ABC1 k141_2452_5 1288826.MSNKSG1_00476 1.47e-172 487.0 COG2199@1|root,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,4681U@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain ydaM GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016740,GO:0016772,GO:0016779,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043900,GO:0043902,GO:0044093,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051252,GO:0052621,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1903506,GO:2000112,GO:2001141 2.7.7.65 ko:K19707,ko:K21088 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko03021 - - - GGDEF,PAS_4,PAS_8,PAS_9 k141_18482_1 59538.XP_005964252.1 3.05e-15 75.5 COG0318@1|root,KOG1176@2759|Eukaryota,38GCS@33154|Opisthokonta,3BD3H@33208|Metazoa,3CS1H@33213|Bilateria,4898P@7711|Chordata,497K4@7742|Vertebrata,3J9E1@40674|Mammalia 33208|Metazoa I acyl-CoA synthetase family member 3 - - 6.2.1.8 ko:K18661,ko:K22133 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01558,R03383 RC00004,RC00137,RC00179 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_18482_2 1278309.KB907099_gene2657 3.33e-101 296.0 COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,1RRB8@1236|Gammaproteobacteria,1XKVJ@135619|Oceanospirillales 135619|Oceanospirillales S MOSC domain - - - - - - - - - - - - MOSC k141_1792_2 525897.Dbac_2998 1.49e-17 85.5 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42PE9@68525|delta/epsilon subdivisions,2WJU1@28221|Deltaproteobacteria,2M9H2@213115|Desulfovibrionales 28221|Deltaproteobacteria T response regulator, receiver - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Response_reg,SpoIIE k141_1792_3 305700.B447_00220 6.58e-25 110.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales 206389|Rhodocyclales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9 k141_15738_1 1123261.AXDW01000001_gene1388 2.86e-41 147.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1X3E5@135614|Xanthomonadales 135614|Xanthomonadales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_15738_2 519989.ECTPHS_00420 2.31e-12 62.4 COG3242@1|root,COG3242@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2065) yjeT - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_15738_3 765913.ThidrDRAFT_3568 1.45e-94 289.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_10110_1 1177154.Y5S_03458 1.33e-19 88.2 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHXR@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM k141_10110_2 765912.Thimo_0632 2.76e-58 188.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1WXYX@135613|Chromatiales 135613|Chromatiales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_4576_1 1502852.FG94_02756 8.98e-31 118.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,47296@75682|Oxalobacteraceae 28216|Betaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_19875_1 766499.C357_21112 1.64e-55 195.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067,ko:K06192 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_8113_1 1208321.D104_03810 1.26e-42 149.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XIT8@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_22000_2 1232683.ADIMK_3988 1.57e-66 208.0 2BCXJ@1|root,326IF@2|Bacteria,1RHTJ@1224|Proteobacteria,1S7YR@1236|Gammaproteobacteria,467I1@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22000_3 1248232.BANQ01000057_gene3012 2.62e-15 74.3 COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,1RYEE@1236|Gammaproteobacteria,1XW9N@135623|Vibrionales 135623|Vibrionales L Restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - HARE-HTH,Mrr_N,Mrr_cat k141_9381_2 1123517.JOMR01000001_gene441 2.34e-26 109.0 2F0VY@1|root,33TXM@2|Bacteria,1NVBB@1224|Proteobacteria,1SNJU@1236|Gammaproteobacteria,4629H@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - PilZ k141_12255_1 467661.RKLH11_305 1.27e-123 360.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,3ZGB9@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K14981 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_13623_2 1163409.UUA_02236 9.43e-83 268.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,1MUA6@1224|Proteobacteria,1SZXB@1236|Gammaproteobacteria,1X4T0@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the Orn Lys Arg decarboxylase class-II family lysA - 2.7.2.4,4.1.1.20 ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_5938_1 1123401.JHYQ01000006_gene101 9.23e-44 148.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,46126@72273|Thiotrichales 72273|Thiotrichales I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) - - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA k141_5938_2 998674.ATTE01000001_gene3062 9.9e-39 134.0 2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,1SATY@1236|Gammaproteobacteria,463FB@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_5938_3 713586.KB900536_gene512 3.71e-43 151.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_17817_1 1232683.ADIMK_3709 3.05e-66 213.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,465AI@72275|Alteromonadaceae 1236|Gammaproteobacteria S permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_15739_1 1168059.KB899087_gene742 9.82e-93 287.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3F0KV@335928|Xanthobacteraceae 28211|Alphaproteobacteria S repeat protein - - - - - - - - - - - - LVIVD k141_14278_1 1278309.KB907104_gene884 3.11e-72 224.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran k141_14278_2 1278309.KB907104_gene883 0.0 886.0 COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1XHV0@135619|Oceanospirillales 135619|Oceanospirillales P Na+/Pi-cotransporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans k141_14278_3 1278309.KB907104_gene882 5.36e-140 399.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,1XJPP@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family UPF0066 - - - - - - - - - - - - UPF0066 k141_10112_1 1117318.PRUB_05336 1.89e-33 125.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,2Q17Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria J With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_13624_1 207954.MED92_07346 7.47e-64 214.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XH69@135619|Oceanospirillales 135619|Oceanospirillales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_19876_1 583345.Mmol_1524 3.51e-40 147.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,2KKUH@206350|Nitrosomonadales 206350|Nitrosomonadales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1g,tRNA_bind k141_19876_2 1163617.SCD_n01870 2.64e-11 63.5 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria 28216|Betaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_22001_1 941449.dsx2_3263 1.53e-50 175.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WJ0I@28221|Deltaproteobacteria,2MG34@213115|Desulfovibrionales 28221|Deltaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_15755_1 351016.RAZWK3B_07514 5.92e-44 151.0 COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,2P1T0@2433|Roseobacter 28211|Alphaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - HTH_20,LMWPc k141_15755_2 52598.EE36_13873 1.81e-28 110.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TU32@28211|Alphaproteobacteria,3ZVB2@60136|Sulfitobacter 28211|Alphaproteobacteria G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gap3 - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_1113_1 396588.Tgr7_1673 1.3e-20 90.5 COG2267@1|root,COG2267@2|Bacteria,1N2KV@1224|Proteobacteria 1224|Proteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_1113_2 631362.Thi970DRAFT_04271 7.02e-79 252.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales 135613|Chromatiales O PFAM Magnesium chelatase, ChlI subunit - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_19883_1 1288826.MSNKSG1_00526 2.54e-60 201.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_19883_2 1131553.JIBI01000039_gene1941 1.81e-50 172.0 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,2VNRP@28216|Betaproteobacteria,372MR@32003|Nitrosomonadales 28216|Betaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,DUF2934,OSCP k141_10139_1 1288826.MSNKSG1_11463 2.58e-104 311.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,464E9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_5270_1 1278309.KB907100_gene2093 3.1e-105 313.0 2AAYF@1|root,310BX@2|Bacteria,1RESE@1224|Proteobacteria,1S5GS@1236|Gammaproteobacteria,1XPJG@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5270_2 1278309.KB907100_gene2092 6.7e-185 516.0 COG0463@1|root,COG0463@2|Bacteria,1RFXT@1224|Proteobacteria,1S5PY@1236|Gammaproteobacteria,1XP92@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyltransferase family 92 - - - - - - - - - - - - Glyco_tranf_2_4 k141_5270_3 1278309.KB907100_gene2091 9.33e-112 326.0 2ECBC@1|root,3369Q@2|Bacteria,1NCNS@1224|Proteobacteria,1SU8Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nucleotide-diphospho-sugar transferase - - - - - - - - - - - - Nucleotid_trans k141_5270_4 1278309.KB907100_gene2090 6.29e-34 132.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C k141_5270_5 1278309.KB907100_gene2089 1.37e-153 437.0 arCOG09486@1|root,2ZC3Y@2|Bacteria,1RD8N@1224|Proteobacteria,1S6S8@1236|Gammaproteobacteria,1XPF2@135619|Oceanospirillales 135619|Oceanospirillales S Glycosyl transferase family 11 - - - - - - - - - - - - Glyco_transf_11 k141_5270_6 1278309.KB907100_gene2088 2.77e-145 420.0 COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,1S9D2@1236|Gammaproteobacteria,1XRWV@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_22011_1 909663.KI867150_gene2358 1.37e-43 154.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2WIJ0@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_22011_2 998674.ATTE01000001_gene2794 2.46e-24 98.6 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,4600R@72273|Thiotrichales 72273|Thiotrichales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_20730_2 1120953.AUBH01000006_gene2637 5.56e-49 166.0 COG1776@1|root,COG2201@1|root,COG1776@2|Bacteria,COG2201@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,4651Z@72275|Alteromonadaceae 1236|Gammaproteobacteria T cheY-homologous receiver domain cheC - - - - - - - - - - - Response_reg k141_22162_1 626887.J057_22425 2.44e-34 132.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_22162_2 1122218.KB893653_gene1243 8.28e-93 291.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,1JS2V@119045|Methylobacteriaceae 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_14424_1 1317118.ATO8_12906 8.08e-88 264.0 COG0395@1|root,COG0395@2|Bacteria,1MVVT@1224|Proteobacteria,2TQJF@28211|Alphaproteobacteria,4KKRX@93682|Roseivivax 28211|Alphaproteobacteria U ABC transporter permease smoG - - ko:K10229 ko02010,map02010 M00200 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.5 - - BPD_transp_1 k141_14424_2 83219.PM02_09395 3.49e-14 70.5 COG1175@1|root,COG1175@2|Bacteria,1MVF1@1224|Proteobacteria,2TST1@28211|Alphaproteobacteria,3ZW1B@60136|Sulfitobacter 28211|Alphaproteobacteria G Binding-protein-dependent transport system inner membrane component smoF - - ko:K10228 ko02010,map02010 M00200 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.5 - - BPD_transp_1 k141_12458_1 251221.35211576 6.58e-32 125.0 COG1178@1|root,COG1178@2|Bacteria,1G1J7@1117|Cyanobacteria 1117|Cyanobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_1283_1 1049564.TevJSym_ar00110 1.99e-109 323.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1J4NT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_1283_2 666681.M301_1175 3.27e-14 76.6 COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,2VWJT@28216|Betaproteobacteria,2KP0B@206350|Nitrosomonadales 206350|Nitrosomonadales P Cobalt transport protein - - - - - - - - - - - - CbiQ k141_1283_3 1163398.AJJP01000093_gene4089 3.64e-12 71.2 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_15907_1 215803.DB30_0461 2.16e-51 188.0 COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,43BK1@68525|delta/epsilon subdivisions,2X6XW@28221|Deltaproteobacteria,2YZAU@29|Myxococcales 28221|Deltaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg k141_21501_1 1397666.RS24_00252 6.68e-12 64.3 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,4BQIP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_21501_2 697282.Mettu_0298 1.64e-14 70.5 2AUTZ@1|root,31KH1@2|Bacteria,1QIC9@1224|Proteobacteria,1TG6N@1236|Gammaproteobacteria,1XFT8@135618|Methylococcales 135618|Methylococcales S PilZ domain - - - - - - - - - - - - PilZ k141_21501_3 323261.Noc_0919 3.31e-220 638.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_13141_1 1288826.MSNKSG1_04496 3.87e-282 771.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,467I6@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase aspC - 2.6.1.1,2.6.1.84 ko:K00812,ko:K12252 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08197 RC00006,RC00008 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_13141_2 1288826.MSNKSG1_04501 1.36e-17 80.9 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_19390_1 1042876.PPS_0522 9.65e-78 250.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1YXFI@136845|Pseudomonas putida group 1236|Gammaproteobacteria F Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 DXP_synthase_N,Transket_pyr,Transketolase_C k141_19390_2 1492922.GY26_18365 3.41e-29 112.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1J4S7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_6752_1 1116375.VEJY3_04790 2.83e-32 117.0 COG3381@1|root,COG3381@2|Bacteria,1RJ3Z@1224|Proteobacteria,1S8M5@1236|Gammaproteobacteria,1XTZ3@135623|Vibrionales 135623|Vibrionales O Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor torD - - ko:K03533 ko02020,map02020 - - - ko00000,ko00001,ko02000 5.A.3.4 - - Nitrate_red_del k141_6752_2 1116375.VEJY3_04795 3.98e-46 154.0 COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XSI9@135623|Vibrionales 135623|Vibrionales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain torR - - ko:K07772 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_20731_1 317025.Tcr_0227 1.64e-23 104.0 COG0683@1|root,COG2200@1|root,COG2204@1|root,COG0683@2|Bacteria,COG2200@2|Bacteria,COG2204@2|Bacteria,1N299@1224|Proteobacteria,1S1MD@1236|Gammaproteobacteria,462CH@72273|Thiotrichales 72273|Thiotrichales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,Response_reg k141_11034_1 1134474.O59_004306 6.68e-25 97.8 2CMCS@1|root,32SEB@2|Bacteria,1N7SY@1224|Proteobacteria,1SDCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11034_2 1134474.O59_004305 6.7e-123 363.0 COG5351@1|root,COG5351@2|Bacteria,1R3ZF@1224|Proteobacteria,1S0MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2169 k141_5463_1 765914.ThisiDRAFT_0453 2.58e-111 335.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1WWQP@135613|Chromatiales 135613|Chromatiales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_12459_1 1033802.SSPSH_002382 2.99e-49 176.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_20744_3 511.JT27_14625 4.66e-48 161.0 COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2VSDB@28216|Betaproteobacteria,3T4UV@506|Alcaligenaceae 28216|Betaproteobacteria S DinB family - - - - - - - - - - - - DinB k141_17281_1 391615.ABSJ01000041_gene59 9.38e-166 493.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1J4YE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_19403_1 227377.CBU_1840 2.14e-31 118.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1JCF8@118969|Legionellales 118969|Legionellales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_3382_1 545264.KB898758_gene2692 1.54e-34 127.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1WWYB@135613|Chromatiales 135613|Chromatiales M Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_3382_2 272624.lpg2613 4.07e-89 273.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1JCPX@118969|Legionellales 118969|Legionellales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_8871_1 111780.Sta7437_1759 3.81e-24 95.5 COG0645@1|root,COG0645@2|Bacteria,1G714@1117|Cyanobacteria 1117|Cyanobacteria S Cell division protein ZipA - - - - - - - - - - - - AAA_33 k141_8871_2 1122599.AUGR01000006_gene3850 1.58e-59 187.0 COG1846@1|root,COG1846@2|Bacteria,1RM3A@1224|Proteobacteria,1SSFM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR_2 k141_8871_3 1122599.AUGR01000006_gene3849 1.11e-53 172.0 COG1942@1|root,COG1942@2|Bacteria,1RAXK@1224|Proteobacteria,1SG5J@1236|Gammaproteobacteria,1XMUE@135619|Oceanospirillales 135619|Oceanospirillales S 4-oxalocrotonate tautomerase - - - - - - - - - - - - Tautomerase k141_8871_4 1288826.MSNKSG1_14072 2.17e-73 234.0 COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,1RMXR@1236|Gammaproteobacteria,46CEW@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_1302_1 472759.Nhal_1884 2.03e-170 489.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WZYK@135613|Chromatiales 135613|Chromatiales H Belongs to the RtcB family - - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_6117_1 396588.Tgr7_2153 8.85e-137 402.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_18705_1 426114.THI_3047 5.51e-73 233.0 COG1633@1|root,COG1633@2|Bacteria,1R5XX@1224|Proteobacteria,2WGRU@28216|Betaproteobacteria 28216|Betaproteobacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - FA_desaturase_2 k141_14441_1 314262.MED193_20039 3.83e-83 258.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2P2K3@2433|Roseobacter 28211|Alphaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12485_1 1288826.MSNKSG1_11843 8.41e-54 184.0 2C593@1|root,2Z84R@2|Bacteria,1Q8PC@1224|Proteobacteria,1RP26@1236|Gammaproteobacteria,46680@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12485_2 1288826.MSNKSG1_11848 1.12e-305 832.0 COG0026@1|root,COG0026@2|Bacteria,1MVHP@1224|Proteobacteria,1RSAE@1236|Gammaproteobacteria,4659Z@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) - - - - - - - - - - - - - k141_8872_1 1278309.KB907099_gene2799 1.14e-90 276.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XH2G@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_17282_1 1202962.KB907168_gene2206 4.43e-05 45.8 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria E oligopeptidase prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_17282_2 1265756.AWZW01000013_gene1416 6.72e-42 148.0 COG2706@1|root,COG3210@1|root,COG4655@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG4655@2|Bacteria,1QUXB@1224|Proteobacteria 1224|Proteobacteria U 6-phosphogluconolactonase activity - - - - - - - - - - - - Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR k141_574_1 1298593.TOL_2567 1.38e-35 132.0 COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,1RS9J@1236|Gammaproteobacteria 1236|Gammaproteobacteria M glycosyl transferase group 1 wcaI - - ko:K03208 - - - - ko00000 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_574_2 395494.Galf_1273 1.73e-24 100.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,44VAE@713636|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k141_6772_1 269796.Rru_A2001 5.88e-45 159.0 COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,2U1IH@28211|Alphaproteobacteria,2JPW1@204441|Rhodospirillales 204441|Rhodospirillales S Protein conserved in bacteria - - - - - - - - - - - - DUF2219 k141_18058_2 214092.YPO2383 1.37e-09 55.8 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,41G6A@629|Yersinia 1236|Gammaproteobacteria O Belongs to the glutaredoxin family. Monothiol subfamily grxD GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - ko:K07390 - - - - ko00000,ko03029,ko03110 - - iPC815.YPO2383,iYL1228.KPN_01992 Glutaredoxin k141_9562_1 404589.Anae109_4239 2.03e-73 239.0 COG0654@1|root,COG0654@2|Bacteria,1R03K@1224|Proteobacteria,43CQQ@68525|delta/epsilon subdivisions,2X7Y6@28221|Deltaproteobacteria,2Z1K0@29|Myxococcales 28221|Deltaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 k141_20022_1 765869.BDW_03445 4.95e-140 435.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_16577_2 207954.MED92_14213 1.41e-93 276.0 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,1S934@1236|Gammaproteobacteria,1XJDC@135619|Oceanospirillales 135619|Oceanospirillales G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_16577_3 207954.MED92_14218 1.48e-196 550.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria,1XI6Q@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_16577_4 1122599.AUGR01000031_gene9 6.37e-111 325.0 COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,1RR7B@1236|Gammaproteobacteria,1XI38@135619|Oceanospirillales 135619|Oceanospirillales K COG3327 Phenylacetic acid-responsive transcriptional repressor - - - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C k141_2637_1 1278309.KB907100_gene1848 1.1e-195 575.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_9 k141_2637_2 1278309.KB907100_gene1847 5.81e-111 327.0 COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,1XJKQ@135619|Oceanospirillales 135619|Oceanospirillales S Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - ko:K03796 - - - - ko00000 - GH73 - Glucosaminidase k141_2637_3 1278309.KB907100_gene1846 3.58e-106 315.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1XHX0@135619|Oceanospirillales 135619|Oceanospirillales C lysine 2,3-aminomutase epmB - - ko:K19810 - - - - ko00000,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM k141_11706_1 95619.PM1_0200440 1.41e-71 218.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Redox protein regulator of disulfide bond formation yhfA - - ko:K07397 - - - - ko00000 - - - OsmC k141_4787_1 326442.PSHAa2692 1.64e-92 290.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2PZK8@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NU (MSHA) biogenesis protein MshE mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N k141_15939_1 1173028.ANKO01000219_gene470 1.23e-70 239.0 COG5001@1|root,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1H9V4@1150|Oscillatoriales 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - CBS,CHASE4,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_20745_1 1288826.MSNKSG1_06118 4.67e-180 510.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,4642Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_8873_1 1120999.JONM01000002_gene951 2.36e-61 197.0 COG0204@1|root,COG0204@2|Bacteria 2|Bacteria I Acyl-transferase cmk - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase,Cytidylate_kin k141_575_1 225937.HP15_3922 7.8e-43 144.0 COG2050@1|root,COG2050@2|Bacteria,1MZB4@1224|Proteobacteria,1SBIC@1236|Gammaproteobacteria,46BU0@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT k141_21510_1 1232683.ADIMK_3256 5.08e-241 670.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4650C@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0348 Polyferredoxin ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_21510_2 1278309.KB907103_gene1071 7.41e-182 509.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1XH7T@135619|Oceanospirillales 135619|Oceanospirillales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_21510_3 1278309.KB907103_gene1073 4.84e-134 381.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1XH6P@135619|Oceanospirillales 135619|Oceanospirillales C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_21510_4 1278309.KB907103_gene1074 0.0 931.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1XIIV@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_21510_5 1278309.KB907103_gene1075 1.67e-107 313.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1XK3I@135619|Oceanospirillales 135619|Oceanospirillales S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_5,Abhydrolase_6,DLH,Hydrolase_4 k141_21510_6 1278309.KB907103_gene1076 5.9e-236 651.0 COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,1XHUQ@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily rlmM - 2.1.1.186 ko:K06968 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_21510_7 1278309.KB907103_gene1077 3.29e-53 167.0 COG2329@1|root,COG2329@2|Bacteria,1N861@1224|Proteobacteria,1SC9H@1236|Gammaproteobacteria,1XM7V@135619|Oceanospirillales 135619|Oceanospirillales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_21510_8 1278309.KB907103_gene1078 1.31e-43 142.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,1XKYB@135619|Oceanospirillales 135619|Oceanospirillales O Sulfur carrier protein TusA tusA - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_21510_9 1278309.KB907103_gene1079 1.79e-74 226.0 COG3109@1|root,COG3109@2|Bacteria,1N68T@1224|Proteobacteria,1RP4S@1236|Gammaproteobacteria,1XJXH@135619|Oceanospirillales 135619|Oceanospirillales T RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities - - - ko:K03607 - - - - ko00000 - - - ProQ k141_12486_1 1415778.JQMM01000001_gene768 4.33e-10 67.8 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RRFS@1236|Gammaproteobacteria,1J73S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_6120_1 926556.Echvi_3057 2.12e-94 288.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_17283_1 1237149.C900_01512 1.73e-32 118.0 COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,47JCH@768503|Cytophagia 976|Bacteroidetes L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_17283_2 643867.Ftrac_2181 5.98e-15 70.1 2DNB6@1|root,32WJ7@2|Bacteria,4NU0X@976|Bacteroidetes,47R0E@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_17283_3 153721.MYP_1648 7.86e-63 197.0 COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,47KW3@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 k141_18706_1 1286106.MPL1_10677 1.77e-16 79.3 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,460N9@72273|Thiotrichales 72273|Thiotrichales NU TIGRFAM type IV pilus biogenesis stability protein PilW - - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_2,TPR_8 k141_18706_2 857087.Metme_3943 9.45e-86 265.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XDXR@135618|Methylococcales 135618|Methylococcales J PFAM Aminoacyl-tRNA synthetase, class II (G H P S), conserved region hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_3385_1 1123279.ATUS01000004_gene2984 1.08e-18 80.1 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1J5WX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_3385_2 1298593.TOL_1722 1.96e-84 271.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_15940_2 998088.B565_1532 2.41e-88 271.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1Y3UU@135624|Aeromonadales 135624|Aeromonadales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_8294_3 1288826.MSNKSG1_16611 3.87e-300 818.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RYNH@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - - - - - - - - - - Peripla_BP_6 k141_8294_4 1288826.MSNKSG1_16606 4.1e-46 156.0 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SYZX@1236|Gammaproteobacteria,464DW@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_2638_1 1288826.MSNKSG1_08918 6.44e-149 436.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,4645D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) aidA - - - - - - - - - - - DUF1302 k141_10332_1 1123247.AUIJ01000004_gene1115 2.17e-21 91.3 COG0115@1|root,COG0115@2|Bacteria,1MX5D@1224|Proteobacteria,2TRVR@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_10332_2 1288298.rosmuc_02156 3.9e-71 222.0 COG3719@1|root,COG3719@2|Bacteria,1PTUN@1224|Proteobacteria,2TQUU@28211|Alphaproteobacteria,46PX8@74030|Roseovarius 28211|Alphaproteobacteria J Belongs to the RNase T2 family rns - 3.1.27.1,3.1.27.6 ko:K01166,ko:K01169 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_T2 k141_10332_3 367336.OM2255_08170 1.94e-129 372.0 COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_20925 - - ko:K09987 - - - - ko00000 - - - DUF1013 k141_13844_1 1288826.MSNKSG1_14822 1.14e-126 370.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,465KP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_13844_2 1288826.MSNKSG1_14827 1.01e-200 559.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,464VA@72275|Alteromonadaceae 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N k141_13844_3 1288826.MSNKSG1_14832 1.17e-115 331.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,466J1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_13844_4 1288826.MSNKSG1_14837 2.68e-119 347.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,463ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein containing LysM domain lysM - - - - - - - - - - - LysM k141_19404_1 76114.ebB231 1.05e-32 117.0 2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2VSVB@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_19404_2 1123228.AUIH01000049_gene376 1.3e-48 166.0 COG2227@1|root,COG2227@2|Bacteria,1RM6F@1224|Proteobacteria 1224|Proteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_12487_1 491952.Mar181_2673 5.84e-103 304.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XJ8R@135619|Oceanospirillales 135619|Oceanospirillales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_8401_3 886293.Sinac_1726 9.14e-35 126.0 COG0231@1|root,COG0231@2|Bacteria,2IZCU@203682|Planctomycetes 203682|Planctomycetes J Elongation factor P (EF-P) OB domain - - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_20961_1 983917.RGE_45690 4.88e-47 155.0 2C1WR@1|root,32N8M@2|Bacteria,1NSYD@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_11206_1 765911.Thivi_3223 3.33e-43 159.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales 135613|Chromatiales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_11206_2 1265313.HRUBRA_01674 5.87e-25 98.6 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1J6ES@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_5615_1 545276.KB898728_gene171 1.45e-82 249.0 COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,1S50T@1236|Gammaproteobacteria,1X0TJ@135613|Chromatiales 135613|Chromatiales O OsmC-like protein - - - - - - - - - - - - OsmC k141_13291_1 269799.Gmet_1139 1.9e-38 131.0 COG3628@1|root,COG3628@2|Bacteria,1N039@1224|Proteobacteria,43DQ3@68525|delta/epsilon subdivisions,2WR64@28221|Deltaproteobacteria,43VVC@69541|Desulfuromonadales 28221|Deltaproteobacteria S Gene 25-like lysozyme - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 k141_13291_2 269799.Gmet_1140 8.12e-176 502.0 COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,42MUS@68525|delta/epsilon subdivisions,2WK02@28221|Deltaproteobacteria 28221|Deltaproteobacteria S homolog of phage Mu protein gp47 - - - - - - - - - - - - - k141_13291_3 269799.Gmet_1141 1.35e-47 171.0 COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,437D2@68525|delta/epsilon subdivisions,2XA15@28221|Deltaproteobacteria,43VQR@69541|Desulfuromonadales 28221|Deltaproteobacteria S homolog of phage Mu protein gp47 - - - - - - - - - - - - - k141_21643_1 1278309.KB907099_gene3100 7.67e-07 49.3 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,1RMWJ@1236|Gammaproteobacteria,1XHJG@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the HpcH HpaI aldolase family hpaI - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI k141_21643_2 1278309.KB907099_gene3099 3e-181 505.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria,1XHX7@135619|Oceanospirillales 135619|Oceanospirillales Q hydratase - - - ko:K02509 ko00350,ko01120,map00350,map01120 - R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 - - - FAA_hydrolase k141_8402_1 999141.GME_14510 1.95e-72 230.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XHSK@135619|Oceanospirillales 135619|Oceanospirillales J SAM-dependent - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_15380_1 999541.bgla_2g10020 2.07e-63 211.0 COG1609@1|root,COG1609@2|Bacteria,1R7XE@1224|Proteobacteria,2WFFK@28216|Betaproteobacteria,1KI1F@119060|Burkholderiaceae 28216|Betaproteobacteria K periplasmic binding protein LacI transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_10489_1 744979.R2A130_3420 1.44e-40 147.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_10489_2 571166.KI421509_gene1734 1.17e-103 310.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TTM5@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate frc - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 k141_742_1 236097.ADG881_2494 5.72e-161 469.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_32_2 1278309.KB907110_gene3201 1.27e-88 265.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1XHFA@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_4909_1 1487956.DR71_23 1.67e-41 146.0 COG0518@1|root,COG0518@2|Bacteria,2GKS1@201174|Actinobacteria,22MU3@1653|Corynebacteriaceae 201174|Actinobacteria F glutamine amidotransferase - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k141_6297_1 1288826.MSNKSG1_03635 1.43e-65 204.0 2FB4I@1|root,343AY@2|Bacteria,1P0MU@1224|Proteobacteria,1SS4Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6297_2 1288826.MSNKSG1_03630 1.71e-148 417.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,465FZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the SUA5 family yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Sua5_yciO_yrdC k141_6297_3 1288826.MSNKSG1_03625 1.63e-78 233.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,46865@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the BolA IbaG family bolA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_6297_4 1288826.MSNKSG1_03620 0.0 1316.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,46593@72275|Alteromonadaceae 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0006139,GO:0006259,GO:0006265,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0022402,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0051304,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_6297_5 1288826.MSNKSG1_03615 1.14e-170 476.0 COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,1S4AS@1236|Gammaproteobacteria,46AIY@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_11207_1 314271.RB2654_20623 4.66e-14 71.2 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TTPD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamine synthetase glnA GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_11207_2 1342299.Z947_872 9.8e-105 310.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,3ZV3R@60136|Sulfitobacter 28211|Alphaproteobacteria E Binding-protein-dependent transport system inner membrane component potI GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11074 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 k141_20962_2 519989.ECTPHS_08643 2.84e-36 129.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1WXRU@135613|Chromatiales 135613|Chromatiales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_14687_1 1122139.KB907883_gene343 9.37e-64 207.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,1XHTX@135619|Oceanospirillales 135619|Oceanospirillales M Phospholipase pldA - 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - PLA1 k141_7014_2 2340.JV46_03540 2.03e-210 585.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4IE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 Gp_dh_C,Gp_dh_N k141_7014_3 396588.Tgr7_2893 1.73e-218 623.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1WVWH@135613|Chromatiales 135613|Chromatiales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_13292_1 323848.Nmul_A1669 3.91e-83 258.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,3733V@32003|Nitrosomonadales 28216|Betaproteobacteria O AIR synthase related protein, N-terminal domain - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_12592_1 1085623.GNIT_0735 4.44e-70 221.0 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,469JR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_18160_2 1288826.MSNKSG1_12187 1.2e-67 209.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,466TN@72275|Alteromonadaceae 1236|Gammaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - iYL1228.KPN_03664 Biotin_lipoyl k141_18160_3 1288826.MSNKSG1_12182 4.09e-99 288.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,4671T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0560 DHquinase_II k141_18160_4 1288826.MSNKSG1_12177 1.73e-144 420.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,46630@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,HDOD,Response_reg k141_11884_1 550540.Fbal_2615 6.99e-51 173.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Ketoacyl-synt_C,ketoacyl-synt k141_11884_2 317025.Tcr_1946 1.4e-99 291.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,460E0@72273|Thiotrichales 72273|Thiotrichales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_20963_1 713586.KB900536_gene1889 3.07e-22 87.8 2C07H@1|root,2ZCWQ@2|Bacteria,1P4TT@1224|Proteobacteria,1SV96@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10490_1 197221.22294524 1.33e-61 197.0 COG0637@1|root,COG0637@2|Bacteria,1G2T2@1117|Cyanobacteria 1117|Cyanobacteria S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - - - - - - - - - - HAD_2 k141_5617_1 1286106.MPL1_02888 2.05e-63 206.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,460K2@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_10491_1 420324.KI911970_gene1454 6.54e-09 56.2 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_10491_2 418443.A2I806_9CAUD 3.03e-09 60.5 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k141_12593_2 1463903.JOIZ01000008_gene4342 2.1e-36 148.0 COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2GJYH@201174|Actinobacteria 201174|Actinobacteria O Belongs to the peptidase S8 family - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - LGFP,P_proprotein,Peptidase_S8 k141_9794_1 1288826.MSNKSG1_01018 5.06e-42 143.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,464P9@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ompR - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_9794_3 1288826.MSNKSG1_01008 2.16e-123 351.0 COG3038@1|root,COG3038@2|Bacteria 2|Bacteria C cytochrome b561 cybB - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_9794_4 1288826.MSNKSG1_01003 2.43e-306 837.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,463YQ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains dctD - - ko:K08476,ko:K10126 ko02020,map02020 M00503,M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_15393_2 1288826.MSNKSG1_01938 8.27e-141 399.0 COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,1RQQB@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator ybiH GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141 - - - - - - - - - - DUF1956,TetR_N k141_15393_3 1288826.MSNKSG1_01943 1.7e-136 393.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,46DF0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like ybhG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_20988_1 1278309.KB907099_gene2603 4.67e-165 467.0 COG4927@1|root,COG4927@2|Bacteria,1MY0W@1224|Proteobacteria,1RRGV@1236|Gammaproteobacteria,1XIEG@135619|Oceanospirillales 135619|Oceanospirillales S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_43_1 1304885.AUEY01000013_gene3124 1.58e-104 313.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2WK97@28221|Deltaproteobacteria,2MJAQ@213118|Desulfobacterales 28221|Deltaproteobacteria S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_3532_1 1408444.JHYC01000001_gene1235 8.35e-86 263.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1SYTB@1236|Gammaproteobacteria,1JC5J@118969|Legionellales 118969|Legionellales S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA k141_11897_1 768671.ThimaDRAFT_4026 5.61e-46 149.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales 135613|Chromatiales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_11897_2 1415778.JQMM01000001_gene904 1.1e-35 127.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1J72N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG3030 Protein affecting phage T7 exclusion by the F plasmid fxsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K07113 - - - - ko00000 - - - FxsA k141_7732_1 926560.KE387023_gene1234 1.38e-27 115.0 COG2379@1|root,COG2379@2|Bacteria,1WI14@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Hydroxypyruvate reductase - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_4922_1 1278309.KB907101_gene437 1.38e-236 679.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XHGI@135619|Oceanospirillales 135619|Oceanospirillales P cation transport ATPase - - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_10513_1 1288494.EBAPG3_27530 2.14e-49 176.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,371VT@32003|Nitrosomonadales 28216|Betaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_5638_1 1305737.JAFX01000001_gene313 9.41e-12 67.4 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISMED2,AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y k141_3533_1 765913.ThidrDRAFT_1427 8.69e-11 61.6 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1WWKK@135613|Chromatiales 135613|Chromatiales O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_20989_1 2340.JV46_09960 3.02e-108 325.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_13308_1 1134474.O59_000056 4.97e-127 375.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1FH21@10|Cellvibrio 1236|Gammaproteobacteria U Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_6310_1 1123057.P872_03915 4e-46 166.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,47KJE@768503|Cytophagia 976|Bacteroidetes S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 k141_7033_1 929703.KE386491_gene2163 3.21e-76 239.0 COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia 976|Bacteroidetes S Alpha beta hydrolase - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 k141_20273_1 880072.Desac_0330 8.12e-105 323.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales 28221|Deltaproteobacteria K two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_4923_1 869213.JCM21142_104353 5.52e-62 203.0 COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,47P4M@768503|Cytophagia 976|Bacteroidetes O prohibitin homologues - - - - - - - - - - - - Band_7 k141_11898_2 1237149.C900_03755 1.94e-61 199.0 29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_4209_3 583345.Mmol_0550 2.57e-09 55.1 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,2W81A@28216|Betaproteobacteria,2KNAK@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 k141_4209_4 686340.Metal_1813 1.05e-28 111.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XEXY@135618|Methylococcales 135618|Methylococcales S SURF1-like protein - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_5639_1 626887.J057_02430 4.45e-18 86.3 COG1352@1|root,COG5001@1|root,COG1352@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465FS@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,CBS,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_5639_2 998674.ATTE01000001_gene1493 9.11e-25 97.1 COG2018@1|root,COG2018@2|Bacteria,1RIQC@1224|Proteobacteria,1S65Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Roadblock LC7 family protein - - - ko:K07131 - - - - ko00000 - - - Robl_LC7 k141_2130_1 1288826.MSNKSG1_13182 0.0 1042.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RX68@1236|Gammaproteobacteria,46688@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2203 FOG GAF domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3 k141_20990_1 1461580.CCAS010000011_gene1525 2e-20 89.4 COG2227@1|root,COG2227@2|Bacteria,1UNRR@1239|Firmicutes,4IUMV@91061|Bacilli,1ZFUP@1386|Bacillus 91061|Bacilli H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - TehB k141_14830_1 1049564.TevJSym_ai00210 1.28e-109 335.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1J4VX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_12718_1 472759.Nhal_0473 6.54e-61 192.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1WZHN@135613|Chromatiales 135613|Chromatiales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_19003_1 523791.Kkor_2461 5.38e-34 119.0 COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1S9PR@1236|Gammaproteobacteria,1XKPX@135619|Oceanospirillales 135619|Oceanospirillales H enzyme involved in biosynthesis of extracellular polysaccharides - - - - - - - - - - - - ABM k141_2238_1 1278309.KB907105_gene1525 1.33e-109 327.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XHR4@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_16903_1 1415778.JQMM01000001_gene1282 4.96e-25 108.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1J5MY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2206 HD-GYP domain - - - - - - - - - - - - DUF3391,HD,HD_5 k141_16903_2 768671.ThimaDRAFT_0724 2.18e-05 43.1 2C7TU@1|root,32RJT@2|Bacteria,1N2CD@1224|Proteobacteria,1S96C@1236|Gammaproteobacteria,1WYZ5@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8545_1 767434.Fraau_2026 5.73e-103 311.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1X2XK@135614|Xanthomonadales 135614|Xanthomonadales O Cysteine desulfurase activator complex subunit SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 k141_17602_1 2340.JV46_06320 4.39e-23 90.9 COG5007@1|root,COG5007@2|Bacteria 2|Bacteria K 2 iron, 2 sulfur cluster binding yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - - - - - - - - - - BolA k141_17602_2 1265490.JHVY01000005_gene1524 1.52e-54 182.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the EPSP synthase family. MurA subfamily murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_7855_1 1288826.MSNKSG1_09563 9.75e-117 338.0 COG0668@1|root,COG0668@2|Bacteria,1QATN@1224|Proteobacteria,1RRIZ@1236|Gammaproteobacteria,468QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel protein MscS - - - - - - - - - - - - MS_channel k141_7855_2 1288826.MSNKSG1_09558 5.91e-240 662.0 COG1638@1|root,COG1638@2|Bacteria 2|Bacteria G carbohydrate transport - - - - - - - - - - - - DctP k141_7855_3 1288826.MSNKSG1_09553 2.55e-195 544.0 COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,466BE@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - ko:K07052 - - - - ko00000 - - - EamA k141_7855_4 1288826.MSNKSG1_09548 4.56e-57 177.0 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,468FM@72275|Alteromonadaceae 1236|Gammaproteobacteria L GIY-YIG catalytic domain yhbQ GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_7855_5 1288826.MSNKSG1_09543 3.91e-192 535.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,4687P@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0657 Esterase lipase - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 k141_7855_6 1288826.MSNKSG1_09538 5.64e-254 696.0 COG2267@1|root,COG2267@2|Bacteria,1RAQZ@1224|Proteobacteria,1S2YX@1236|Gammaproteobacteria,467BE@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_7855_7 1288826.MSNKSG1_09533 6.23e-136 387.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,464H3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family yiaD - - ko:K12216 - - - - ko00000,ko02044 3.A.7.9.1 - - Gly-zipper_Omp,Gly-zipper_YMGG,OmpA k141_7855_8 1288826.MSNKSG1_09528 2.6e-61 194.0 COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,1S5Z3@1236|Gammaproteobacteria,46B6Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S PAP2 superfamily - - - - - - - - - - - - PAP2 k141_9207_2 1232683.ADIMK_0097 9.49e-97 292.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1SYZ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,Cupin_2,HTH_18 k141_10655_1 713586.KB900536_gene2311 8.6e-78 247.0 COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,1RR3N@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG2010 Cytochrome c, mono- and diheme variants nirN - - - - - - - - - - - Cytochrom_D1,Cytochrome_CBB3 k141_20411_1 1255043.TVNIR_1189 1.7e-53 182.0 COG1653@1|root,COG1653@2|Bacteria,1R5DC@1224|Proteobacteria,1S3CM@1236|Gammaproteobacteria,1X05G@135613|Chromatiales 135613|Chromatiales G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 k141_20411_2 1121335.Clst_2533 7.61e-17 79.7 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae 186801|Clostridia K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 k141_4369_1 236097.ADG881_445 3.8e-16 85.1 COG2207@1|root,COG2207@2|Bacteria,1NUXY@1224|Proteobacteria,1SNBP@1236|Gammaproteobacteria,1XR9X@135619|Oceanospirillales 135619|Oceanospirillales K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_21763_1 411154.GFO_1623 4.05e-44 149.0 COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia 976|Bacteroidetes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_21763_2 761193.Runsl_0056 8.28e-54 172.0 COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia 976|Bacteroidetes P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_2980_1 395493.BegalDRAFT_0038 2.42e-121 369.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales 72273|Thiotrichales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_9906_2 518766.Rmar_0079 4.66e-30 114.0 COG2010@1|root,COG2010@2|Bacteria,4NYF1@976|Bacteroidetes 976|Bacteroidetes C Domain of unknown function (DUF4405) - - - - - - - - - - - - DUF4405 k141_9906_3 395494.Galf_0056 2.58e-29 108.0 2C84F@1|root,334ZR@2|Bacteria,1N6VS@1224|Proteobacteria,2VWHA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_14131_1 2340.JV46_02890 1.72e-35 125.0 2E3G3@1|root,32YEY@2|Bacteria,1N87D@1224|Proteobacteria,1SDRX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14842_1 231434.JQJH01000002_gene2385 6.5e-09 55.8 COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,3N9WH@45404|Beijerinckiaceae 28211|Alphaproteobacteria L Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_14842_2 391613.RTM1035_12613 6.24e-95 281.0 COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,2TS1K@28211|Alphaproteobacteria,46PXK@74030|Roseovarius 28211|Alphaproteobacteria I Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP pcs GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 ko:K01004 ko00564,ko01110,map00564,map01110 - R05794 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_12729_1 713586.KB900536_gene1289 2.58e-57 202.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C k141_12028_1 1288826.MSNKSG1_04846 1.41e-215 601.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,465PC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD_5 k141_12028_2 1288826.MSNKSG1_04841 2.07e-125 358.0 2FDBS@1|root,345DK@2|Bacteria,1P196@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_12028_3 1288826.MSNKSG1_04836 1.39e-56 176.0 2E9Z2@1|root,3344J@2|Bacteria,1N825@1224|Proteobacteria,1SE0S@1236|Gammaproteobacteria,468DX@72275|Alteromonadaceae 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_12028_4 1288826.MSNKSG1_04831 6.2e-80 245.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,4645A@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1840 ABC-type Fe3 transport system, periplasmic component fbpA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k141_2981_2 452471.Aasi_0758 7.52e-40 133.0 COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,47R60@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_16199_1 1530186.JQEY01000002_gene1516 1.45e-148 437.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0339 Zn-dependent oligopeptidases dcp GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_1573_1 34506.g3028 3.1e-92 288.0 2EGUQ@1|root,2SMPF@2759|Eukaryota,3ADXV@33154|Opisthokonta,3BZA8@33208|Metazoa,3DFB0@33213|Bilateria 33208|Metazoa S Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4 k141_1573_2 187272.Mlg_2661 1.86e-11 65.1 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1WWEB@135613|Chromatiales 135613|Chromatiales D Part of the ABC transporter FtsEX involved in cellular division - - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_7155_2 290398.Csal_2397 7.65e-21 89.7 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_7155_3 517417.Cpar_0506 5.23e-100 317.0 COG0474@1|root,COG0474@2|Bacteria 2|Bacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.6 ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_14132_1 395493.BegalDRAFT_0394 2.18e-115 344.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,45ZSM@72273|Thiotrichales 72273|Thiotrichales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_19012_1 765913.ThidrDRAFT_0094 4.36e-37 143.0 COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1WX4X@135613|Chromatiales 135613|Chromatiales S PFAM von Willebrand factor type A - - - - - - - - - - - - VWA,VWA_3 k141_876_2 296591.Bpro_4522 1.87e-49 171.0 COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2VHUP@28216|Betaproteobacteria,4AC7Q@80864|Comamonadaceae 28216|Betaproteobacteria E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_9907_2 697282.Mettu_0743 5.85e-79 244.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1XDJA@135618|Methylococcales 135618|Methylococcales S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_5792_2 1123392.AQWL01000006_gene572 1.57e-75 248.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1KS7I@119069|Hydrogenophilales 119069|Hydrogenophilales MU Outer membrane efflux protein - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_16904_1 270374.MELB17_15806 1.88e-22 100.0 COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria,465VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_6440_1 292415.Tbd_0085 5.96e-65 221.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg k141_8548_1 1040989.AWZU01000024_gene6480 1.29e-49 166.0 COG0546@1|root,COG0546@2|Bacteria,1REXF@1224|Proteobacteria,2VG24@28211|Alphaproteobacteria,3JSJQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S HAD-hyrolase-like MA20_36165 - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_12731_1 105559.Nwat_0777 6.06e-95 292.0 COG0739@1|root,COG3061@1|root,COG0739@2|Bacteria,COG3061@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales 135613|Chromatiales M PFAM peptidase - - - - - - - - - - - - OapA,Peptidase_M23 k141_14133_1 1415754.JQMK01000002_gene3311 5e-33 129.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,464I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel k141_15554_1 1458275.AZ34_13835 1.58e-08 53.1 2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,2VVR9@28216|Betaproteobacteria,4AF0J@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF2818) - - - - - - - - - - - - DUF2818 k141_15554_2 472759.Nhal_3687 1.39e-108 328.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_21149_1 1278309.KB907099_gene2952 8.16e-147 424.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1XH5J@135619|Oceanospirillales 135619|Oceanospirillales K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR k141_21149_2 1278309.KB907099_gene2951 4.75e-211 585.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,1XHZF@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k141_21149_3 1278309.KB907099_gene2950 3.73e-19 84.3 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XI54@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9208_1 1469613.JT55_19045 3.71e-102 304.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3FCPS@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_7859_1 999141.GME_19132 1.03e-38 143.0 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1RY9Y@1236|Gammaproteobacteria,1XIPH@135619|Oceanospirillales 135619|Oceanospirillales S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_14843_1 1121439.dsat_2827 1.56e-40 150.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2WJY9@28221|Deltaproteobacteria,2M8FD@213115|Desulfovibrionales 28221|Deltaproteobacteria I SMART Phospholipid glycerol acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_14843_2 697282.Mettu_3480 1.04e-141 434.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_10656_1 1283300.ATXB01000001_gene1274 5.47e-17 82.8 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1XDT5@135618|Methylococcales 135618|Methylococcales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_10656_2 550540.Fbal_3483 1.08e-59 191.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_16905_1 396588.Tgr7_2123 4.11e-94 293.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_8549_1 317025.Tcr_2034 4.42e-07 49.7 2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,1SCE8@1236|Gammaproteobacteria,461C0@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF4389) - - - - - - - - - - - - DUF4389 k141_8549_2 795666.MW7_0669 1.23e-31 119.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VRHW@28216|Betaproteobacteria,1KH1X@119060|Burkholderiaceae 28216|Betaproteobacteria O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_20412_1 1260251.SPISAL_07325 6.45e-151 444.0 COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1X2EG@135613|Chromatiales 135613|Chromatiales P PUA-like domain - - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 k141_20412_2 1268237.G114_08817 1.77e-26 105.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1Y4CQ@135624|Aeromonadales 135624|Aeromonadales P 3'(2'),5'-bisphosphate nucleotidase - - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_16201_1 204773.HEAR1124 7.21e-12 67.8 COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,2VMJW@28216|Betaproteobacteria,475A5@75682|Oxalobacteraceae 28216|Betaproteobacteria M COG3980 Spore coat polysaccharide biosynthesis protein - - - - - - - - - - - - Acetyltransf_3,Glyco_tran_28_C k141_12030_2 519989.ECTPHS_02901 2.95e-29 112.0 COG1652@1|root,COG1652@2|Bacteria 2|Bacteria S positive regulation of growth rate ygaU GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0030955,GO:0031420,GO:0035864,GO:0040008,GO:0040009,GO:0040010,GO:0042221,GO:0043167,GO:0043169,GO:0045927,GO:0046872,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007 - ko:K21687,ko:K21688,ko:K21689,ko:K21690,ko:K21691 - - - - ko00000 - GH23 - LysM,Peptidase_M23,Transglycosylas k141_11373_1 1288826.MSNKSG1_04086 8.4e-153 447.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,463YC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Anticodon_1,tRNA-synt_1g,tRNA_bind k141_11373_3 1288826.MSNKSG1_04076 1.7e-118 340.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,464VR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_11373_4 1288826.MSNKSG1_04071 3.44e-232 650.0 COG1842@1|root,COG4656@1|root,COG1842@2|Bacteria,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,4655V@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_17603_1 1278309.KB907106_gene1214 3.83e-98 304.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XIKC@135619|Oceanospirillales 135619|Oceanospirillales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_17603_2 1278309.KB907106_gene1215 1.18e-40 134.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1XM4G@135619|Oceanospirillales 135619|Oceanospirillales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_17603_3 207954.MED92_05029 8.59e-93 276.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XJ5P@135619|Oceanospirillales 135619|Oceanospirillales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k141_17603_4 203122.Sde_1147 0.000133 50.1 2EB1E@1|root,33529@2|Bacteria,1N9EM@1224|Proteobacteria,1SDNI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type II secretion system protein B - - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB k141_5033_1 1636270.A0A0E3JPE6_9CAUD 7.08e-21 90.9 4QB55@10239|Viruses,4QSJ0@28883|Caudovirales,4QNGX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k141_5033_3 1517681.HW45_03735 8.09e-17 92.8 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria,1XW5S@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k141_4521_1 1122201.AUAZ01000002_gene1028 8.61e-96 290.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH k141_8038_1 1123247.AUIJ01000001_gene1472 1.41e-41 149.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_8038_2 391593.RCCS2_02018 2.66e-63 194.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2P33Q@2433|Roseobacter 28211|Alphaproteobacteria K Belongs to the P(II) protein family glnB GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_7287_2 1532558.JL39_29900 1.19e-18 91.7 COG1672@1|root,COG1672@2|Bacteria,1Q77U@1224|Proteobacteria,2UT6J@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Archaeal ATPase - - - - - - - - - - - - - k141_17768_1 1278309.KB907102_gene89 8.32e-34 125.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1XHSC@135619|Oceanospirillales 135619|Oceanospirillales P Iron deficiency-induced protein A - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 k141_17768_2 1278309.KB907102_gene90 5.15e-121 350.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,1XJ5U@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_12886_1 1168065.DOK_06125 3.6e-75 244.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_21941_1 1123247.AUIJ01000002_gene2387 7.83e-68 219.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains ntrC - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_19172_1 1049564.TevJSym_aw00330 4.12e-64 207.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k141_19172_2 1249627.D779_4232 9.59e-52 174.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales 135613|Chromatiales S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k141_316_1 1288826.MSNKSG1_17546 2.62e-184 524.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,46A56@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_316_2 1288826.MSNKSG1_17541 1.72e-89 261.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,468PW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske k141_316_3 1288826.MSNKSG1_17536 3.53e-168 470.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,466BU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SfsA family sfsA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K06206 - - - - ko00000 - - - SfsA k141_316_4 1288826.MSNKSG1_17531 2.88e-99 288.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,466DH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_316_5 1288826.MSNKSG1_17526 2.16e-206 571.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,466ES@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_316_6 1288826.MSNKSG1_17521 4.94e-39 129.0 2EFYT@1|root,339QZ@2|Bacteria,1NG9A@1224|Proteobacteria,1SH9T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MFS transporter HA62_05660 - - - - - - - - - - - - k141_316_7 1288826.MSNKSG1_17516 3.07e-151 452.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,4643M@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_11476_2 1056820.KB900632_gene2210 9.87e-73 234.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,2PMN4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria K Segregation and condensation complex subunit ScpB scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB k141_11476_3 1168065.DOK_09806 4.46e-25 102.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1J4MQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_6541_2 243233.MCA1336 9.92e-124 362.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XE2M@135618|Methylococcales 135618|Methylococcales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_6541_3 1122201.AUAZ01000016_gene67 4.51e-23 95.5 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,46867@72275|Alteromonadaceae 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k141_12176_1 675815.VOA_002860 4.3e-99 300.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XSWN@135623|Vibrionales 135623|Vibrionales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_16314_1 686340.Metal_2963 2.01e-34 126.0 COG3272@1|root,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XEGF@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_16314_2 91464.S7335_3510 1.84e-50 164.0 2CD0I@1|root,32RWS@2|Bacteria,1G74B@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF4399) - - - - - - - - - - - - DUF4399 k141_8039_1 1395571.TMS3_0105425 1.55e-19 85.5 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S2P6@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Pilus assembly protein pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO k141_8039_2 1283300.ATXB01000001_gene2122 1.53e-15 74.7 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1XF1T@135618|Methylococcales 135618|Methylococcales NU PFAM Fimbrial assembly - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_17769_1 269796.Rru_A3741 3.95e-78 245.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2JP8I@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI k141_1005_1 1278309.KB907099_gene2606 1.64e-75 228.0 COG4125@1|root,COG4125@2|Bacteria,1RHF1@1224|Proteobacteria,1SBGV@1236|Gammaproteobacteria,1XS9K@135619|Oceanospirillales 135619|Oceanospirillales S Chlorhexidine efflux transporter - - - - - - - - - - - - BTP k141_1005_2 1278309.KB907099_gene2607 9.74e-158 447.0 COG0583@1|root,COG0583@2|Bacteria,1MVGZ@1224|Proteobacteria,1RRFH@1236|Gammaproteobacteria,1XK20@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_2393_1 292415.Tbd_0601 8.36e-14 70.5 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,2VN1T@28216|Betaproteobacteria,1KSVG@119069|Hydrogenophilales 119069|Hydrogenophilales C Domain of unknown function (DUF4931) - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - - k141_2393_2 640081.Dsui_3262 3.1e-112 326.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,2KUU9@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_317_1 1122603.ATVI01000005_gene3015 1.16e-56 188.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1X33Q@135614|Xanthomonadales 135614|Xanthomonadales M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_7288_1 506534.Rhein_2512 3.99e-46 160.0 COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs cmoM GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_13537_1 626887.J057_07431 7.56e-09 57.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,466WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_13537_2 1382306.JNIM01000001_gene1281 1.05e-11 65.9 COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi 200795|Chloroflexi T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_13537_3 228410.NE0570 6.11e-13 67.8 2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,2VX4M@28216|Betaproteobacteria,373MK@32003|Nitrosomonadales 28216|Betaproteobacteria S Domain of unknown function (DUF4389) - - - - - - - - - - - - DUF4389 k141_13537_4 1280950.HJO_04705 8.37e-32 118.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,43W7G@69657|Hyphomonadaceae 28211|Alphaproteobacteria S MazG family mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG k141_11477_1 1205680.CAKO01000008_gene4081 1.08e-08 54.3 COG0346@1|root,COG0346@2|Bacteria,1N4A2@1224|Proteobacteria 1224|Proteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_11477_2 1402135.SUH3_09440 2.09e-47 164.0 28HPH@1|root,2Z7XH@2|Bacteria,1Q80I@1224|Proteobacteria,2TVGE@28211|Alphaproteobacteria,3ZWGQ@60136|Sulfitobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_14943_1 1240350.AMZE01000122_gene3452 1.84e-69 226.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1YV0G@136845|Pseudomonas putida group 1236|Gammaproteobacteria S PFAM Amidohydrolase 3 - - - - - - - - - - - - Amidohydro_3 k141_15649_1 94122.Shewana3_0302 2.25e-109 329.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria,2QCVD@267890|Shewanellaceae 1236|Gammaproteobacteria K PFAM helix-turn-helix- domain containing protein, AraC type - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15649_2 94122.Shewana3_0303 8.79e-128 369.0 COG1028@1|root,COG1028@2|Bacteria,1N8G3@1224|Proteobacteria,1RZ80@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short,adh_short_C2 k141_15649_3 223926.28808549 1.39e-100 293.0 COG1917@1|root,COG1917@2|Bacteria,1N0BS@1224|Proteobacteria,1SBE0@1236|Gammaproteobacteria,1XWAF@135623|Vibrionales 135623|Vibrionales S ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 k141_15649_4 1116375.VEJY3_17271 2.67e-169 482.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RWRJ@1236|Gammaproteobacteria,1XWEE@135623|Vibrionales 135623|Vibrionales E Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_1024_2 1237149.C900_01566 1.07e-53 181.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia 976|Bacteroidetes E PFAM Sodium alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_16321_1 396588.Tgr7_0702 2.21e-54 179.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-Transferase yqjG - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_6559_1 312153.Pnuc_1001 6.77e-09 54.3 COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria,1K9Q6@119060|Burkholderiaceae 28216|Betaproteobacteria P Nitrite reductase nirD - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Rieske,Rieske_2 k141_6559_2 1287116.X734_05070 1.12e-93 300.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,43IR1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_2415_2 1120953.AUBH01000001_gene1115 2.18e-68 214.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,466JV@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050 Formyl_trans_N k141_7305_1 1123401.JHYQ01000012_gene2851 2.71e-27 118.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,4619H@72273|Thiotrichales 72273|Thiotrichales H HemX, putative uroporphyrinogen-III C-methyltransferase - - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX k141_1751_1 1123237.Salmuc_02524 1.09e-125 364.0 COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,2TRM5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC-type sugar transport systems permease components - - - ko:K17316 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_337_1 713587.THITH_08275 2.91e-95 296.0 COG1075@1|root,COG1075@2|Bacteria,1MXMP@1224|Proteobacteria,1RYZM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - PGAP1 k141_17051_1 1278309.KB907104_gene852 4.22e-162 467.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RRSQ@1236|Gammaproteobacteria,1XIIN@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the BCCT transporter (TC 2.A.15) family - - - - - - - - - - - - BCCT k141_17051_2 1278309.KB907104_gene851 1.58e-230 635.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQ31@1236|Gammaproteobacteria,1XHBJ@135619|Oceanospirillales 135619|Oceanospirillales E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - - - - - - - - - - Peptidase_M19 k141_17051_3 1278309.KB907104_gene850 0.0 905.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RVXM@1236|Gammaproteobacteria,1XI3N@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_17051_4 1278309.KB907104_gene849 3.29e-203 563.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RZ6S@1236|Gammaproteobacteria,1XICR@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_8691_1 1288826.MSNKSG1_17641 5.7e-131 380.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,464H7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iJN746.PP_0436 S4,tRNA-synt_1b k141_21957_1 1165841.SULAR_02488 3.04e-17 84.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42USK@68525|delta/epsilon subdivisions,2YPZR@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_20591_1 338966.Ppro_2399 1.59e-107 330.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales 28221|Deltaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_13560_1 1454004.AW11_01233 1.79e-05 53.1 COG1618@1|root,COG1618@2|Bacteria 2|Bacteria F nucleotide phosphatase activity, acting on free nucleotides - - - - - - - - - - - - PqqD k141_12191_1 216595.PFLU_5748 2.57e-06 54.7 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1YNX1@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria T Histidine kinase chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_11494_2 1502851.FG93_03903 5.77e-39 143.0 COG3503@1|root,COG3503@2|Bacteria,1RA1Q@1224|Proteobacteria,2U5Y1@28211|Alphaproteobacteria,3K3W1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1624) - - - - - - - - - - - - DUF1624 k141_8063_1 1385935.N836_16225 1.9e-134 384.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_4540_1 207954.MED92_14178 1.76e-109 332.0 COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RS4V@1236|Gammaproteobacteria,1XHIA@135619|Oceanospirillales 135619|Oceanospirillales T PFAM Extracellular solute-binding protein, family 3 - - - - - - - - - - - - HATPase_c,HisKA,SBP_bac_3 k141_2416_1 643867.Ftrac_1697 6.71e-102 308.0 COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,47K6M@768503|Cytophagia 976|Bacteroidetes S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_21285_2 1042375.AFPL01000051_gene139 6.65e-28 110.0 COG2200@1|root,COG2200@2|Bacteria,1RA10@1224|Proteobacteria,1S71H@1236|Gammaproteobacteria 1236|Gammaproteobacteria T EAL domain - - - - - - - - - - - - EAL k141_13561_2 1415756.JQMY01000001_gene2391 2.85e-56 193.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2PCEU@252301|Oceanicola 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain dctB - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_19191_1 326442.PSHAa0366 6.77e-50 173.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,2Q0IM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N k141_17052_2 351348.Maqu_0914 1.94e-06 48.5 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_7306_1 1469245.JFBG01000001_gene538 3.31e-29 114.0 COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S alpha beta - - - - - - - - - - - - DUF3530 k141_16323_1 323261.Noc_0136 7.26e-91 274.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1WW7W@135613|Chromatiales 135613|Chromatiales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_21958_1 2340.JV46_28110 9.72e-120 367.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1J4ZW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_2417_1 1288826.MSNKSG1_12932 8.49e-119 365.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,464KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_1025_2 580332.Slit_0143 3.95e-35 123.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria 28216|Betaproteobacteria P Rhodanese domain protein pspE2 - - - - - - - - - - - Rhodanese k141_3809_1 697282.Mettu_0818 4.68e-26 103.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XFK3@135618|Methylococcales 135618|Methylococcales S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 k141_21286_1 571166.KI421509_gene3906 4.44e-16 76.3 COG1853@1|root,COG1853@2|Bacteria,1MXPE@1224|Proteobacteria,2TS7H@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct k141_21286_2 1237149.C900_03563 1.29e-30 122.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family wzc - - - - - - - - - - - AAA_31,GNVR,Wzz k141_3153_1 396588.Tgr7_2760 3.11e-63 199.0 COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales 135613|Chromatiales Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_25 k141_3153_2 765912.Thimo_3383 1.22e-80 253.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1WW2W@135613|Chromatiales 135613|Chromatiales P PFAM sodium hydrogen exchanger - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_10058_1 1278309.KB907100_gene1863 1.21e-86 256.0 COG1765@1|root,COG1765@2|Bacteria,1QUE7@1224|Proteobacteria,1S84Z@1236|Gammaproteobacteria,1XKED@135619|Oceanospirillales 135619|Oceanospirillales O OsmC-like protein - - - - - - - - - - - - OsmC k141_10058_2 1278309.KB907100_gene1859 3.95e-213 592.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1XIFP@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta,DNA_pol3_gamma3 k141_12361_1 713587.THITH_08655 1.19e-54 175.0 COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1WY49@135613|Chromatiales 135613|Chromatiales P PFAM Rhodanese-like - - - - - - - - - - - - Rhodanese k141_12361_2 870187.Thini_0149 4.66e-19 84.0 COG2932@1|root,COG2932@2|Bacteria,1NBZE@1224|Proteobacteria,1S6MQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Peptidase S24-like - - - - - - - - - - - - Peptidase_S24 k141_10948_1 1237149.C900_02809 1.15e-99 310.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia 976|Bacteroidetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_15077_1 663610.JQKO01000011_gene3364 9.09e-58 182.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,3NB4F@45404|Beijerinckiaceae 28211|Alphaproteobacteria O SelR domain msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_15077_2 768671.ThimaDRAFT_2533 3.35e-142 410.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 135613|Chromatiales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_5370_1 187272.Mlg_2624 7.88e-102 321.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_5370_2 395493.BegalDRAFT_0738 2.25e-47 166.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales 72273|Thiotrichales T response regulator receiver - - - - - - - - - - - - DUF229,HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat k141_4680_1 1278309.KB907101_gene280 3.44e-265 745.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_10214_1 1123517.JOMR01000001_gene845 5.2e-21 93.6 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,461P8@72273|Thiotrichales 72273|Thiotrichales O Membrane-bound serine protease (ClpP class) - - - ko:K07403 - - - - ko00000 - - - NfeD k141_17922_1 386456.JQKN01000003_gene234 1.73e-05 48.9 arCOG07611@1|root,arCOG09729@1|root,arCOG07611@2157|Archaea,arCOG09729@2157|Archaea 2157|Archaea E Polymorphic membrane protein, Chlamydia - - - - - - - - - - - - Beta_helix,Big_3_5,Chlam_PMP,DUF11 k141_17922_2 315730.BcerKBAB4_4761 1.25e-57 180.0 COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli,1ZH56@1386|Bacillus 91061|Bacilli P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_17922_4 1120919.AUBI01000005_gene802 1.93e-84 265.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,2JPDC@204441|Rhodospirillales 204441|Rhodospirillales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k141_22069_1 1328313.DS2_15974 5.27e-113 340.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,464EE@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretory pathway, component PulF mshG - - ko:K02505,ko:K12278 - - - - ko00000,ko02044 - - - T2SSF k141_488_1 1479237.JMLY01000001_gene1098 4.99e-43 162.0 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1MXVB@1224|Proteobacteria,1RMNV@1236|Gammaproteobacteria,465QR@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - HDOD,tRNA_edit k141_9458_1 1125863.JAFN01000001_gene2891 3.41e-19 86.3 28IZ5@1|root,33FUK@2|Bacteria,1NKT0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_9458_2 870187.Thini_3261 1.17e-47 159.0 COG0526@1|root,COG0526@2|Bacteria,1N3S8@1224|Proteobacteria,1SZG3@1236|Gammaproteobacteria,463T6@72273|Thiotrichales 72273|Thiotrichales CO Thioredoxin-like domain - - - - - - - - - - - - AhpC-TSA k141_9458_3 373903.Hore_21320 6.83e-15 83.6 COG2199@1|root,COG3706@2|Bacteria,1TT1S@1239|Firmicutes,24HUD@186801|Clostridia,3WBGJ@53433|Halanaerobiales 186801|Clostridia T diguanylate cyclase - - - - - - - - - - - - GAF,GGDEF k141_2538_1 391626.OAN307_c25790 8.2e-81 248.0 COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,2U2CW@28211|Alphaproteobacteria 28211|Alphaproteobacteria K helix_turn _helix lactose operon repressor rbtR - - ko:K02529,ko:K03435 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_4 k141_19953_1 349521.HCH_04348 3.91e-87 263.0 COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria,1XS5M@135619|Oceanospirillales 135619|Oceanospirillales S O-methyltransferase - - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 k141_1873_1 717774.Marme_3705 1.24e-36 130.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1XK51@135619|Oceanospirillales 135619|Oceanospirillales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_1873_2 472759.Nhal_0210 5.44e-20 85.5 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1WXPI@135613|Chromatiales 135613|Chromatiales F phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_22070_1 1219065.VPR01S_09_00890 3.85e-77 254.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XSU6@135623|Vibrionales 135623|Vibrionales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_17179_1 1500893.JQNB01000001_gene1257 7.61e-122 379.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1X36U@135614|Xanthomonadales 135614|Xanthomonadales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_6686_1 1288826.MSNKSG1_18030 0.0 947.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,464KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - iJN746.PP_5046 Gln-synt_C,Gln-synt_N k141_6686_2 225937.HP15_4000 1.47e-155 449.0 COG2199@1|root,COG3706@2|Bacteria,1NQU1@1224|Proteobacteria,1S1PW@1236|Gammaproteobacteria,46CHG@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_21410_1 929558.SMGD1_1041 1.12e-103 313.0 COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) ptmE - - - - - - - - - - - CBS,NTP_transferase k141_3920_1 314278.NB231_12641 1.38e-30 115.0 COG2119@1|root,COG2119@2|Bacteria 2|Bacteria O membrane - - - - - - - - - - - - UPF0016 k141_3920_2 62928.azo3839 5.38e-70 221.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,2KU6S@206389|Rhodocyclales 206389|Rhodocyclales P Molybdenum ABC transporter periplasmic molybdate-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_19326_1 754477.Q7C_1384 8.44e-61 192.0 COG0235@1|root,COG0235@2|Bacteria,1QAVF@1224|Proteobacteria,1RW3I@1236|Gammaproteobacteria,4628Z@72273|Thiotrichales 72273|Thiotrichales G PFAM Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_19326_2 686340.Metal_2805 6.1e-68 208.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1XF45@135618|Methylococcales 135618|Methylococcales S PFAM Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_4681_1 754477.Q7C_1040 1.72e-79 241.0 2CJUF@1|root,32RVU@2|Bacteria,1RE4Q@1224|Proteobacteria,1S3VX@1236|Gammaproteobacteria,463AP@72273|Thiotrichales 72273|Thiotrichales S TIGRFAM CRISPR-associated protein Cas6 Csy4, subtype I-F YPEST - - - ko:K19130 - - - - ko00000,ko01000,ko02048 - - - Cas_Csy4 k141_16473_1 1236541.BALL01000032_gene3424 7.3e-23 92.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,2QBKF@267890|Shewanellaceae 1236|Gammaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3360 YgbB k141_16473_2 1283300.ATXB01000001_gene2429 9.5e-72 229.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XG4P@135618|Methylococcales 135618|Methylococcales T Two component signalling adaptor domain - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_15835_1 111780.Sta7437_4221 9.67e-65 205.0 COG2755@1|root,COG2755@2|Bacteria,1G5C9@1117|Cyanobacteria,3VNKD@52604|Pleurocapsales 1117|Cyanobacteria E COGs COG2755 Lysophospholipase L1 and related esterase - - - - - - - - - - - - Lipase_GDSL_2 k141_15835_2 1049564.TevJSym_au00340 4.57e-173 489.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1J598@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Oligopeptide transport system permease protein OppB oppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_13742_1 2340.JV46_21960 6.72e-111 352.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5KS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_17924_1 522306.CAP2UW1_3042 2.48e-16 84.0 COG1639@1|root,COG2114@1|root,COG1639@2|Bacteria,COG2114@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria 28216|Betaproteobacteria T HDOD domain - - - - - - - - - - - - HDOD k141_19954_1 1278309.KB907099_gene2467 1.85e-148 439.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XI1I@135619|Oceanospirillales 135619|Oceanospirillales L Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C - - 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_2539_1 52598.EE36_15917 2.63e-160 459.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,3ZVP6@60136|Sulfitobacter 28211|Alphaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_18579_1 930169.B5T_04153 3.05e-24 104.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,1XIZM@135619|Oceanospirillales 135619|Oceanospirillales P Phosphodiesterase alkaline phosphatase D - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_18579_2 1288826.MSNKSG1_09683 1.12e-304 830.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,46524@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0665 Glycine D-amino acid oxidases (deaminating) dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_18579_3 1288826.MSNKSG1_09688 6.4e-80 237.0 COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,4680D@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins yciH GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 k141_7452_1 1249627.D779_1676 9.1e-47 156.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1WYKN@135613|Chromatiales 135613|Chromatiales L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_7452_2 998088.B565_0908 5.17e-13 68.9 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1Y409@135624|Aeromonadales 135624|Aeromonadales L Phage integrase, N-terminal SAM-like domain xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_16474_1 310539.Q5G7N8_9CAUD 1.26e-73 247.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k141_489_1 1097668.BYI23_E000220 6.93e-17 91.3 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K35G@119060|Burkholderiaceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CHASE,EAL,GGDEF,MASE1,PAS,PAS_4,PAS_7,dCache_1 k141_8193_1 1288826.MSNKSG1_12667 8.11e-57 186.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,4653S@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k141_8193_2 1288826.MSNKSG1_12662 6.62e-313 852.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,46457@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the acetyltransferase family. ArgA subfamily argA GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226 AA_kinase,Acetyltransf_1 k141_8193_3 1288826.MSNKSG1_12657 6.99e-243 669.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,46ACH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_8193_4 1288826.MSNKSG1_12652 1.32e-179 535.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - DUF1631,EAL,GGDEF,PilZ k141_1202_1 1236959.BAMT01000005_gene122 3.4e-87 273.0 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2VK6Y@28216|Betaproteobacteria,2KKNF@206350|Nitrosomonadales 206350|Nitrosomonadales C Oxidoreductase NAD-binding domain - - 1.14.13.238 ko:K22343 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_1202_3 1278309.KB907101_gene409 1.64e-230 641.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1XIRA@135619|Oceanospirillales 135619|Oceanospirillales EGP MFS transporter permease - - - - - - - - - - - - MFS_1 k141_1202_4 1278309.KB907101_gene408 1.95e-11 62.8 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XH8U@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_1876_1 1415780.JPOG01000001_gene1425 3.91e-69 222.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RNDN@1236|Gammaproteobacteria,1X5P2@135614|Xanthomonadales 135614|Xanthomonadales E Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs avtA - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 k141_8778_1 1278309.KB907099_gene2854 3.37e-49 169.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XIDR@135619|Oceanospirillales 135619|Oceanospirillales C reductase - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2 k141_8778_2 1232683.ADIMK_1819 4.74e-287 799.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - - - - - - - - - - - PP2C_2,Pkinase k141_8778_3 1122599.AUGR01000021_gene3193 2.53e-132 389.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,1XHYM@135619|Oceanospirillales 135619|Oceanospirillales P Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_5998_1 1278309.KB907099_gene2873 1.46e-49 167.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RQZ8@1236|Gammaproteobacteria,1XIK5@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase FAD-binding domain - - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_5998_2 207954.MED92_14123 4.52e-106 308.0 COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,1S4FY@1236|Gammaproteobacteria,1XJSD@135619|Oceanospirillales 135619|Oceanospirillales S phenylacetate-CoA oxygenase, PaaJ subunit - - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P k141_5998_3 207954.MED92_14118 8.62e-172 480.0 COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,1RRSG@1236|Gammaproteobacteria,1XJ27@135619|Oceanospirillales 135619|Oceanospirillales S Phenylacetic acid catabolic protein - - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_5998_4 207954.MED92_14113 3.92e-67 203.0 COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,1S7F4@1236|Gammaproteobacteria,1XK2N@135619|Oceanospirillales 135619|Oceanospirillales Q Phenylacetic acid degradation B paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB k141_5998_5 207954.MED92_14108 3.64e-219 605.0 COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,1RNRN@1236|Gammaproteobacteria,1XIE2@135619|Oceanospirillales 135619|Oceanospirillales S Phenylacetic acid catabolic protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC k141_5998_6 207954.MED92_14103 1.69e-267 738.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1XH41@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k141_5998_7 1278309.KB907099_gene2879 2.32e-262 722.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XI75@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_5998_8 1278309.KB907099_gene2683 2.99e-68 211.0 COG0664@1|root,COG0664@2|Bacteria,1MZ52@1224|Proteobacteria,1SASM@1236|Gammaproteobacteria,1XKRK@135619|Oceanospirillales 135619|Oceanospirillales T cyclic nucleotide-binding - - - - - - - - - - - - cNMP_binding k141_5998_9 1278309.KB907099_gene2638 4.4e-94 279.0 COG2173@1|root,COG2173@2|Bacteria,1RBFI@1224|Proteobacteria,1S38W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide ddpX - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 k141_17925_1 693746.OBV_05940 1.59e-10 63.9 COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,2N81S@216572|Oscillospiraceae 186801|Clostridia T HDOD domain - - - - - - - - - - - - EAL,HDOD k141_17925_2 1385515.N791_14470 7.19e-49 165.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,1X4VY@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF455 k141_5372_2 1122201.AUAZ01000005_gene491 1.26e-37 138.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,46B93@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma-70, region 4 rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_5372_3 1384056.N787_05285 3.65e-44 151.0 COG2259@1|root,COG2259@2|Bacteria,1RHIY@1224|Proteobacteria,1SIZV@1236|Gammaproteobacteria,1X7C9@135614|Xanthomonadales 135614|Xanthomonadales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_3297_1 261292.Nit79A3_1102 2.21e-121 356.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,37467@32003|Nitrosomonadales 28216|Betaproteobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_17180_1 754476.Q7A_2480 2.13e-113 352.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales 72273|Thiotrichales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_17180_2 1279019.ARQK01000022_gene156 7.14e-25 99.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria,1WXV0@135613|Chromatiales 135613|Chromatiales S Cytokinin riboside 5'-monophosphate phosphoribohydrolase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_13743_1 1232410.KI421412_gene304 2.35e-13 78.2 COG4585@1|root,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,42YNI@68525|delta/epsilon subdivisions,2WTTE@28221|Deltaproteobacteria,43T7V@69541|Desulfuromonadales 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA_3 k141_13067_2 1288826.MSNKSG1_14647 2.32e-258 709.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,4648R@72275|Alteromonadaceae 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_13067_3 1288826.MSNKSG1_14642 0.0 941.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,46444@72275|Alteromonadaceae 1236|Gammaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_13067_4 1288826.MSNKSG1_14637 8.31e-21 82.4 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,4690G@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 k141_13067_6 1288826.MSNKSG1_14627 2.59e-56 174.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,4689Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K08998 - - - - ko00000 - - - Haemolytic k141_13067_7 1288826.MSNKSG1_14622 2.83e-172 494.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,46553@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_18592_1 1294273.roselon_02881 1.43e-36 130.0 COG3909@1|root,COG3909@2|Bacteria,1N1E5@1224|Proteobacteria,2U9A1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - - - - - - - - - - Cytochrom_C_2 k141_12519_1 1040987.AZUY01000034_gene2141 2.63e-56 188.0 COG4963@1|root,COG4963@2|Bacteria 2|Bacteria - - cpaE1 - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg k141_4010_2 551789.ATVJ01000001_gene1569 9.66e-26 101.0 arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,2UEFT@28211|Alphaproteobacteria,43YIZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_6149_1 519989.ECTPHS_02981 7.44e-23 94.4 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales 135613|Chromatiales S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_6149_2 314278.NB231_05811 8.97e-147 429.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_13204_1 754476.Q7A_260 1.37e-135 392.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,4600A@72273|Thiotrichales 72273|Thiotrichales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_20775_1 102129.Lepto7375DRAFT_7035 1.35e-16 85.1 COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k141_8334_1 367336.OM2255_08736 1.11e-85 273.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_11103_1 1122194.AUHU01000004_gene1490 2.35e-35 132.0 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RRA7@1236|Gammaproteobacteria,464FY@72275|Alteromonadaceae 1236|Gammaproteobacteria S zinc-ribbon domain - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k141_16617_1 1288826.MSNKSG1_17491 1.64e-134 385.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,46494@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144 Pantoate_ligase k141_16617_2 1288826.MSNKSG1_17486 6.6e-145 423.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_1808 PGI k141_6791_1 997353.HMPREF9144_1455 6.04e-36 140.0 COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,2FRC8@200643|Bacteroidia 976|Bacteroidetes M RHS repeat-associated core domain protein - - - - - - - - - - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_1349_1 393595.ABO_0247 3.3e-17 79.7 COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria,1XP3M@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 k141_1349_2 1195236.CTER_4880 3.31e-16 76.6 2EG8Z@1|root,32UBD@2|Bacteria,1VBQD@1239|Firmicutes,24NWB@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k141_1349_3 526218.Sterm_1686 1.18e-09 61.2 COG2068@1|root,COG2068@2|Bacteria 2|Bacteria NU MobA-Related Protein ygfJ - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_4817_1 443152.MDG893_17492 1.52e-19 84.7 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,466CT@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0000166,GO:0003674,GO:0003824,GO:0004733,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0010181,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019842,GO:0032553,GO:0032991,GO:0034641,GO:0036094,GO:0042301,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902444 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_4817_2 313606.M23134_01237 1.81e-70 229.0 COG1215@1|root,COG1215@2|Bacteria,4NMSY@976|Bacteroidetes,47NMB@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k141_21548_1 435908.IDSA_10090 1.41e-115 340.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Alpha-E k141_21548_2 1127673.GLIP_1517 3.12e-66 215.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_8906_1 765913.ThidrDRAFT_0365 1.7e-96 295.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales 135613|Chromatiales P PFAM Citrate transporter - - - - - - - - - - - - CitMHS k141_18102_2 717774.Marme_0879 1e-54 194.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales 135619|Oceanospirillales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_17315_1 1278309.KB907102_gene87 6.93e-205 572.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XI7S@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 k141_5515_1 314345.SPV1_12415 8.03e-122 362.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel aefA - - - - - - - - - - - MS_channel k141_7576_1 1408310.JHUW01000010_gene2523 8.67e-10 66.6 COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia 976|Bacteroidetes S tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8 k141_1363_1 1122137.AQXF01000002_gene29 8.46e-93 280.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - DUF3473,Polysacc_deac_1 k141_14493_1 1410620.SHLA_8c000270 3.96e-139 400.0 COG1175@1|root,COG1175@2|Bacteria,1NAGS@1224|Proteobacteria,2UB4V@28211|Alphaproteobacteria,4B81K@82115|Rhizobiaceae 28211|Alphaproteobacteria P Protein involved in transporter activity and transport - - - ko:K02025,ko:K10118 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 k141_8355_1 2340.JV46_26220 1.22e-114 341.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1J4U5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iJN746.PP_0436 S4,tRNA-synt_1b k141_22232_1 1190606.AJYG01000029_gene3038 1.28e-20 95.1 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XTJM@135623|Vibrionales 135623|Vibrionales M 3-deoxy-D-manno-octulosonic-acid transferase kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N k141_16635_2 314292.VAS14_05073 6.01e-32 117.0 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1XXMX@135623|Vibrionales 135623|Vibrionales S FR47-like protein - - - - - - - - - - - - Acetyltransf_10 k141_15991_1 1288826.MSNKSG1_08713 9.13e-59 191.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,466UY@72275|Alteromonadaceae 1236|Gammaproteobacteria M UDP-N-acetylglucosamine 2-epimerase wecB - 3.2.1.183,5.1.3.14 ko:K01791,ko:K08068 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k141_15991_2 1397527.Q670_12965 2.93e-35 130.0 COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,1RS9J@1236|Gammaproteobacteria,1XM49@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1 k141_18755_2 1230342.CTM_14338 1.36e-10 64.3 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,36DV2@31979|Clostridiaceae 186801|Clostridia M membrane protein involved in D-alanine export algI - - ko:K19294 - - - - ko00000 - - - MBOAT k141_15184_2 929556.Solca_4029 4.08e-35 124.0 COG3324@1|root,COG3324@2|Bacteria,4NSBC@976|Bacteroidetes,1IT82@117747|Sphingobacteriia 976|Bacteroidetes S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K06996 - - - - ko00000 - - - Glyoxalase k141_3446_3 1235798.C817_01515 2.18e-07 55.5 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,27VE2@189330|Dorea 186801|Clostridia KT COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain srrA_6 - - - - - - - - - - - Response_reg,Trans_reg_C k141_18121_1 1121374.KB891575_gene1364 5.95e-141 405.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K21711 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_18121_2 1396858.Q666_12815 5.67e-130 380.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria 1236|Gammaproteobacteria EI Biotin carboxylase pycA - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_4830_1 1288826.MSNKSG1_18060 2.52e-91 277.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,466WT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_5516_1 999549.KI421513_gene1041 1.26e-78 238.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,27ZNB@191028|Leisingera 28211|Alphaproteobacteria L RecR protein recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_6168_1 1026882.MAMP_01484 7e-21 90.5 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,45ZX2@72273|Thiotrichales 72273|Thiotrichales P PFAM sodium calcium exchanger - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_6168_2 396588.Tgr7_2450 2.15e-64 209.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1WW1D@135613|Chromatiales 135613|Chromatiales M PFAM VacJ family lipoprotein - - - ko:K04754 - - - - ko00000 - - - MlaA k141_6168_3 498211.CJA_1626 5.96e-26 97.4 2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria,1FHQY@10|Cellvibrio 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19457_1 1116472.MGMO_174c00010 2.68e-95 286.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XDPQ@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF2797) - - - - - - - - - - - - DUF2797 k141_22233_1 1401065.HMPREF2130_04280 3.91e-40 144.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,3T1G3@506|Alcaligenaceae 28216|Betaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_13221_1 631362.Thi970DRAFT_02165 2e-12 63.5 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SX58@1236|Gammaproteobacteria,1WZBH@135613|Chromatiales 135613|Chromatiales S TIGRFAM TIGR02449 family protein - - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_13221_2 1260251.SPISAL_08170 9.84e-23 91.7 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZ69@135613|Chromatiales 135613|Chromatiales D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_13221_3 247633.GP2143_16511 9.89e-38 135.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1J6KP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_3447_1 1488328.JMCL01000030_gene2286 1.31e-10 63.5 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RQTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria L PFAM Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_7578_1 1278309.KB907101_gene390 2.04e-84 263.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XH5Z@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_11121_2 1300350.DSW25_10205 7.59e-21 85.5 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,3ZXWK@60136|Sulfitobacter 28211|Alphaproteobacteria T Belongs to the BolA IbaG family bolA GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - ko:K05527,ko:K22066 - - - - ko00000,ko03000,ko03029 - - - BolA k141_11121_3 367336.OM2255_12537 7.61e-67 208.0 COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria O molecular chaperone - - - - - - - - - - - - DnaJ k141_21559_1 1167006.UWK_02962 1.22e-23 102.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Response regulator receiver - - - - - - - - - - - - ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg k141_21559_2 1049564.TevJSym_ae00650 6.18e-87 265.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_11727_1 1266908.AQPB01000056_gene2097 5.93e-201 579.0 COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,1RQDM@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter - - - - - - - - - - - - ABC_membrane,ABC_tran k141_17329_1 765911.Thivi_3349 8.52e-83 266.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales 135613|Chromatiales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 k141_17329_2 1049564.TevJSym_bw00100 9.35e-55 177.0 2C20N@1|root,32SGJ@2|Bacteria,1N3M9@1224|Proteobacteria,1S9VG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17329_3 203122.Sde_0826 1.58e-07 54.3 COG3063@1|root,COG3063@2|Bacteria,1NQ1E@1224|Proteobacteria,1SHC6@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU TPR repeat - - - - - - - - - - - - - k141_621_1 713586.KB900536_gene1006 4.12e-24 92.4 2C2HW@1|root,32U3B@2|Bacteria,1N2W5@1224|Proteobacteria,1SA05@1236|Gammaproteobacteria,1WYXJ@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_621_2 765913.ThidrDRAFT_2040 4.88e-50 161.0 COG2920@1|root,COG2920@2|Bacteria,1RISY@1224|Proteobacteria,1S8HB@1236|Gammaproteobacteria,1WYQ6@135613|Chromatiales 135613|Chromatiales P Part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_621_3 713586.KB900536_gene1008 4.01e-62 199.0 2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria,1WW2H@135613|Chromatiales 135613|Chromatiales S TIGRFAM CRISPR-associated protein - - - - - - - - - - - - Cas6 k141_8931_2 90813.JQMT01000001_gene2127 8.47e-21 97.1 COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 k141_15185_1 1278309.KB907100_gene1841 4.91e-196 549.0 COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XIU6@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_6169_1 95619.PM1_0204775 9.16e-40 137.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_6169_2 697282.Mettu_3790 1.66e-47 166.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,1XE2Z@135618|Methylococcales 135618|Methylococcales O Peptidase, M48 - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_5517_3 1122134.KB893650_gene852 4.46e-46 155.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1XI5A@135619|Oceanospirillales 135619|Oceanospirillales P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k141_20797_1 870187.Thini_0137 6.84e-39 134.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,460T1@72273|Thiotrichales 72273|Thiotrichales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_2690_1 1278309.KB907099_gene2737 1.75e-82 270.0 COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,1XH4U@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_2690_2 1040983.AXAE01000013_gene5688 1.87e-25 98.6 2E08V@1|root,32VWG@2|Bacteria,1N52T@1224|Proteobacteria,2UU4P@28211|Alphaproteobacteria,43KVE@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_1364_1 1249627.D779_2374 4.11e-121 360.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1WWIC@135613|Chromatiales 135613|Chromatiales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_1364_2 913325.N799_14080 3.54e-58 187.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1X4CF@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes a key regulatory step in fatty acid biosynthesis - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_11122_2 945083.W0LI70_9CAUD 1.76e-22 90.5 4QHC8@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKZT@10699|Siphoviridae 10699|Siphoviridae S D-alanyl-D-alanine carboxypeptidase - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016032,GO:0016787,GO:0019048,GO:0019058,GO:0019076,GO:0019538,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043170,GO:0044003,GO:0044004,GO:0044238,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - - k141_14494_1 317936.Nos7107_3507 4.38e-69 218.0 COG2761@1|root,COG2761@2|Bacteria,1G41Q@1117|Cyanobacteria,1HQK3@1161|Nostocales 1117|Cyanobacteria Q DSBA-like thioredoxin domain - - - - - - - - - - - - DSBA k141_4831_1 1336208.JADY01000019_gene2874 3.66e-146 424.0 COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0IN@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - - - - - - - - - - Amidohydro_1,Amidohydro_3,MGS k141_8932_1 252305.OB2597_04400 3.54e-33 126.0 COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,2TR9Y@28211|Alphaproteobacteria,2PCH6@252301|Oceanicola 28211|Alphaproteobacteria S YcjX-like family, DUF463 MA20_04550 - - ko:K06918 - - - - ko00000 - - - DUF463 k141_8932_2 388399.SSE37_13071 1.62e-12 66.6 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_10396_1 1236541.BALL01000050_gene4249 3.92e-75 230.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,2Q8RY@267890|Shewanellaceae 1236|Gammaproteobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - - - - - - - - - - Transcrip_reg k141_10396_2 1121918.ARWE01000001_gene2624 6.31e-13 67.8 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,42S8N@68525|delta/epsilon subdivisions,2WNCI@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_5518_1 367336.OM2255_13554 1.25e-85 266.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2TRPX@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_6170_1 1305735.JAFT01000005_gene3323 3.21e-13 68.2 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,2PCNA@252301|Oceanicola 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e k141_6170_2 1410620.SHLA_29c000660 3.09e-40 145.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,4B92C@82115|Rhizobiaceae 28211|Alphaproteobacteria E decarboxylase ddc - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC k141_18758_1 1249627.D779_4197 9.49e-56 184.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales 135613|Chromatiales H Belongs to the ribF family - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_13223_1 395493.BegalDRAFT_3524 4.41e-112 330.0 COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,460BF@72273|Thiotrichales 72273|Thiotrichales G PFAM pfkB family carbohydrate kinase - - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_9622_1 1278309.KB907102_gene17 2.11e-73 238.0 COG0175@1|root,COG3415@1|root,COG0175@2|Bacteria,COG3415@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1XHRR@135619|Oceanospirillales 135619|Oceanospirillales EH Phosphoadenosine phosphosulfate reductase family - - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct k141_1994_1 1278309.KB907099_gene2471 1.89e-66 207.0 COG1556@1|root,COG1556@2|Bacteria,1N67T@1224|Proteobacteria,1RNC6@1236|Gammaproteobacteria,1XJ9J@135619|Oceanospirillales 135619|Oceanospirillales S LUD domain - - - - - - - - - - - - LUD_dom k141_1994_2 640081.Dsui_0263 3.11e-98 301.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2VI1Z@28216|Betaproteobacteria,2KWI8@206389|Rhodocyclales 206389|Rhodocyclales C Di-haem cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k141_1994_3 1278309.KB907099_gene2469 0.0 1498.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_9765_2 1209072.ALBT01000006_gene758 2.98e-64 217.0 COG2199@1|root,COG3290@1|root,COG2199@2|Bacteria,COG3290@2|Bacteria,1NV1F@1224|Proteobacteria,1RX70@1236|Gammaproteobacteria,1FI6M@10|Cellvibrio 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GGDEF,PAS_4 k141_5583_1 1131553.JIBI01000003_gene1685 1.22e-05 46.6 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,373DV@32003|Nitrosomonadales 28216|Betaproteobacteria C Succinate dehydrogenase/Fumarate reductase transmembrane subunit sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_1403_1 359.CN09_23650 5.82e-15 73.6 COG3239@1|root,COG3239@2|Bacteria,1R42Z@1224|Proteobacteria,2TU07@28211|Alphaproteobacteria,4B92F@82115|Rhizobiaceae 28211|Alphaproteobacteria I Fatty acid desaturase mocD - - - - - - - - - - - FA_desaturase k141_1403_2 716928.AJQT01000099_gene423 5.91e-33 124.0 COG1879@1|root,COG1879@2|Bacteria,1NZGQ@1224|Proteobacteria,2TT2Z@28211|Alphaproteobacteria,4BBFC@82115|Rhizobiaceae 28211|Alphaproteobacteria G LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_4 k141_707_1 440512.C211_04160 9.3e-50 170.0 COG0637@1|root,COG0637@2|Bacteria,1RKK9@1224|Proteobacteria,1SPIH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HAD-hyrolase-like - - - - - - - - - - - - HAD_2 k141_19530_2 1163617.SCD_n01729 1.74e-42 146.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria 28216|Betaproteobacteria S ATPase associated with various cellular activities, AAA_5 - - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_20918_2 1128421.JAGA01000004_gene2699 4.03e-57 186.0 COG0384@1|root,COG0384@2|Bacteria,2NR2U@2323|unclassified Bacteria 2|Bacteria S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF k141_2792_2 589873.EP13_13250 2.92e-20 93.6 28K2M@1|root,2Z9RY@2|Bacteria,1R6RC@1224|Proteobacteria,1RP9F@1236|Gammaproteobacteria,466KK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Beta_helix k141_14652_1 1198232.CYCME_0641 2.06e-134 389.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,460H9@72273|Thiotrichales 72273|Thiotrichales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_16038_1 1198232.CYCME_0023 2.72e-68 215.0 COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,45ZU6@72273|Thiotrichales 72273|Thiotrichales H Thiamine biosynthesis protein (ThiI) - - - - - - - - - - - - ThiI k141_7681_1 1278309.KB907108_gene1564 3.59e-152 429.0 COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria,1T1MX@1236|Gammaproteobacteria,1XRTY@135619|Oceanospirillales 135619|Oceanospirillales CH Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 fpr - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_21615_1 261292.Nit79A3_0736 1.28e-58 194.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,371PB@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep k141_6977_1 1278309.KB907103_gene1153 5.47e-145 435.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_2105_1 1278309.KB907100_gene2163 7.01e-117 341.0 COG3608@1|root,COG3608@2|Bacteria,1MV55@1224|Proteobacteria,1S6VH@1236|Gammaproteobacteria,1XPHG@135619|Oceanospirillales 135619|Oceanospirillales S Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA k141_16740_1 439496.RBY4I_148 2.45e-188 526.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria 28211|Alphaproteobacteria E threonine dehydratase tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_20220_1 1234364.AMSF01000082_gene2984 5.72e-35 131.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1X65W@135614|Xanthomonadales 135614|Xanthomonadales V MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_12558_1 1283300.ATXB01000001_gene428 3.92e-72 224.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1XFWX@135618|Methylococcales 135618|Methylococcales S VIT family - - - - - - - - - - - - VIT1 k141_17433_1 388399.SSE37_16088 8.62e-34 128.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_20919_1 243924.LT42_14475 2.67e-67 222.0 COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane-associated metal-dependent hydrolase eptA - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1705,Sulfatase k141_4887_1 1485544.JQKP01000003_gene76 2.73e-92 288.0 COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,44V29@713636|Nitrosomonadales 28216|Betaproteobacteria G PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_15349_1 760192.Halhy_5517 0.000291 44.3 COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes 976|Bacteroidetes S membrane - - - ko:K08994 - - - - ko00000,ko02000 1.A.46.2 - - Bestrophin k141_8377_1 661367.LLO_0628 1.03e-57 194.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1JDCB@118969|Legionellales 118969|Legionellales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA rsmB GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_14653_1 1288826.MSNKSG1_08803 3.9e-118 352.0 COG1629@1|root,COG1629@2|Bacteria,1QU6M@1224|Proteobacteria,1T1NT@1236|Gammaproteobacteria,4671Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi k141_18829_1 1304275.C41B8_09496 6.76e-25 98.6 2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18829_2 187272.Mlg_1208 8.64e-105 316.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_13262_1 323848.Nmul_A1098 2.56e-21 92.4 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,371TY@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_13262_2 795666.MW7_1276 1.01e-68 212.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,1K316@119060|Burkholderiaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 k141_13262_3 472759.Nhal_3691 1.1e-17 79.7 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S4ZA@1236|Gammaproteobacteria,1X25S@135613|Chromatiales 135613|Chromatiales C Belongs to the complex I subunit 6 family - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_20221_1 90814.KL370891_gene1875 1.5e-91 280.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,460G1@72273|Thiotrichales 72273|Thiotrichales P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_5584_1 941449.dsx2_1835 3.52e-08 53.9 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria,2M88E@213115|Desulfovibrionales 28221|Deltaproteobacteria G PFAM 6-phosphogluconate dehydrogenase NAD-binding gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2620 6PGD,NAD_binding_2 k141_708_1 1123518.ARWI01000001_gene686 4.68e-80 260.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_18129_1 1286106.MPL1_08544 5.96e-75 235.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,45ZZZ@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_18129_2 225937.HP15_1287 3.68e-61 197.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,4672J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_18129_3 1283284.AZUK01000001_gene695 3.49e-09 56.6 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1Y3N8@135624|Aeromonadales 135624|Aeromonadales C Part of a membrane complex involved in electron transport rnfE - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_19531_4 40571.JOEA01000008_gene2546 2.17e-05 47.8 COG1309@1|root,COG1309@2|Bacteria,2IJ0U@201174|Actinobacteria,4E59F@85010|Pseudonocardiales 201174|Actinobacteria K BetI-type transcriptional repressor, C-terminal - - - - - - - - - - - - TetR_C_6,TetR_N k141_7682_1 1033802.SSPSH_000804 4.52e-14 72.8 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_13950_1 1454004.AW11_03482 1.26e-114 351.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria 28216|Betaproteobacteria P Ferrous iron transport protein B - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_17434_1 314264.ROS217_18042 8.55e-36 139.0 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,46PZ9@74030|Roseovarius 28211|Alphaproteobacteria S GTA TIM-barrel-like domain - - - - - - - - - - - - GTA_TIM,Phage-tail_3 k141_12559_1 1278309.KB907099_gene2815 2.37e-138 397.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1S2UC@1236|Gammaproteobacteria,1XRRN@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_20222_1 1122212.AULO01000008_gene1467 6.67e-88 267.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria,1XH6G@135619|Oceanospirillales 135619|Oceanospirillales E Glycine betaine - - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_15350_1 713586.KB900536_gene2406 7.68e-08 55.1 COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR k141_15350_2 765914.ThisiDRAFT_2541 2.05e-11 63.5 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales 135613|Chromatiales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_5585_1 697282.Mettu_2371 1.87e-05 48.9 COG1629@1|root,COG4771@2|Bacteria,1MXSN@1224|Proteobacteria,1RZC0@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_16741_1 290400.Jann_0336 2.89e-14 67.8 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2U9AI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the bacterial histone-like protein family hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_16741_2 1417296.U879_17035 6.21e-68 219.0 COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations amn GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008714,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - AMNp_N,PNP_UDP_1 k141_11863_1 1123247.AUIJ01000006_gene3274 6.46e-36 132.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_11863_2 1266998.ATUJ01000003_gene1498 8.48e-13 67.4 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,2PUGD@265|Paracoccus 28211|Alphaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - DUF559,SpoU_methylase k141_20921_1 1122201.AUAZ01000003_gene1828 4.31e-08 57.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,464NW@72275|Alteromonadaceae 1236|Gammaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_20921_2 105559.Nwat_2204 6.4e-16 78.2 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1WWRA@135613|Chromatiales 135613|Chromatiales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_14654_1 980584.AFPB01000036_gene3565 3.17e-09 63.2 COG2091@1|root,COG2091@2|Bacteria,4NSR9@976|Bacteroidetes,1I4JQ@117743|Flavobacteriia 976|Bacteroidetes H 4'-phosphopantetheinyl transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_4190_1 1515746.HR45_12270 3.81e-09 60.8 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,2Q8IW@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM porin Gram-negative type ifcO - - - - - - - - - - - Porin_4 k141_6979_1 1235457.C404_01335 9.27e-70 214.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,1K5JG@119060|Burkholderiaceae 28216|Betaproteobacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP k141_19532_1 1123054.KB907716_gene160 3.9e-98 298.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1WX6B@135613|Chromatiales 135613|Chromatiales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_13263_1 224324.aq_097 4.35e-16 79.3 28HPH@1|root,2Z7XH@2|Bacteria,2G4EG@200783|Aquificae 200783|Aquificae - - - - - - - - - - - - - - - k141_21616_1 1123279.ATUS01000001_gene1695 5.6e-110 320.0 COG1432@1|root,COG1432@2|Bacteria,1REF0@1224|Proteobacteria,1S545@1236|Gammaproteobacteria,1J69J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V HNH endonuclease - - - - - - - - - - - - NYN k141_11166_1 287.DR97_2043 1.92e-30 119.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1YFAX@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_18130_1 765914.ThisiDRAFT_0933 4.43e-54 181.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_18130_2 472759.Nhal_0589 1.14e-31 118.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1WW8G@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA k141_16039_1 880072.Desac_1012 2.73e-37 135.0 COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria L PFAM transposase, IS4 family protein - - - - - - - - - - - - - k141_9_1 765913.ThidrDRAFT_2951 1.24e-111 325.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales 135613|Chromatiales C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 k141_18831_1 1122137.AQXF01000003_gene2156 1.93e-86 260.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria 28211|Alphaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_9767_1 1123393.KB891326_gene151 1.32e-19 87.4 2C7AT@1|root,338A4@2|Bacteria,1NF74@1224|Proteobacteria,2W4U0@28216|Betaproteobacteria,1KT29@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_9767_2 90814.KL370891_gene1925 3.57e-30 122.0 COG0526@1|root,COG0526@2|Bacteria,1RB6H@1224|Proteobacteria,1S2QN@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,LGT k141_6284_1 1278309.KB907104_gene939 1.59e-101 304.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XHIB@135619|Oceanospirillales 135619|Oceanospirillales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7 k141_6284_2 1278309.KB907104_gene940 6.07e-140 398.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XHZ7@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_6284_3 1323663.AROI01000026_gene1832 3.25e-21 87.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 k141_6284_4 1278309.KB907104_gene942 3.26e-43 149.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,1XHST@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_12574_2 1278309.KB907104_gene820 6.46e-13 67.4 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XK0P@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion, TssG - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_20250_1 686340.Metal_2497 2.01e-57 189.0 COG0482@1|root,COG0482@2|Bacteria,1QV6H@1224|Proteobacteria,1RQSV@1236|Gammaproteobacteria,1XH1D@135618|Methylococcales 135618|Methylococcales J Thiamine biosynthesis protein (ThiI) - - - - - - - - - - - - - k141_20250_2 1026882.MAMP_02885 7.73e-31 110.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria,461H2@72273|Thiotrichales 72273|Thiotrichales O Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - TusA k141_20250_3 1121935.AQXX01000100_gene1271 1.16e-07 53.9 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XH3K@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer k141_9084_1 472759.Nhal_0222 1.69e-77 255.0 COG0784@1|root,COG2199@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales 135613|Chromatiales T PFAM EAL domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_16761_1 396588.Tgr7_1226 1.17e-42 158.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1WW11@135613|Chromatiales 135613|Chromatiales N TIGRFAM Flagellar hook-associated protein, FlgK flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_19548_1 395493.BegalDRAFT_2469 1.36e-84 273.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_11189_1 517418.Ctha_1018 1.07e-75 234.0 COG3384@1|root,COG3384@2|Bacteria 2|Bacteria S 3-carboxyethylcatechol 2,3-dioxygenase activity - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA,LigB k141_4903_1 28258.KP05_08170 7.92e-41 150.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1XIPZ@135619|Oceanospirillales 135619|Oceanospirillales S protein containing LysM domain - - - - - - - - - - - - LysM k141_11882_1 1123368.AUIS01000009_gene2461 1.23e-35 128.0 COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,1S6MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_11882_2 292415.Tbd_0128 5.84e-17 81.3 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,2VJUY@28216|Betaproteobacteria,1KSYS@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome C oxidase, cbb3-type, subunit III - - 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - - k141_13277_1 1278309.KB907109_gene3254 2.1e-116 345.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XHIH@135619|Oceanospirillales 135619|Oceanospirillales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_7007_1 228410.NE0076 2.52e-80 252.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,372MW@32003|Nitrosomonadales 28216|Betaproteobacteria O PFAM Peptidase M48 htpX_2 - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_16172_8 1288826.MSNKSG1_07348 2.38e-180 505.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,465QS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph k141_3657_1 292415.Tbd_0109 1.51e-102 307.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,1KRA9@119069|Hydrogenophilales 119069|Hydrogenophilales F Amidohydrolase family - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_21129_2 443152.MDG893_13874 1.31e-123 357.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,4649G@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_21129_3 396588.Tgr7_2333 1.73e-80 243.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1WXDE@135613|Chromatiales 135613|Chromatiales J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_21129_4 391615.ABSJ01000035_gene1007 5.1e-47 154.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1J6A7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k141_21129_5 713586.KB900536_gene1177 0.0 1765.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_10638_1 426114.THI_2288 2.04e-11 71.6 COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VSR3@28216|Betaproteobacteria,1KN3G@119065|unclassified Burkholderiales 28216|Betaproteobacteria S NHL repeat - - - - - - - - - - - - NHL k141_7131_1 1278309.KB907099_gene2537 2.33e-85 273.0 COG2911@1|root,COG2911@2|Bacteria,1MUT7@1224|Proteobacteria,1RQ5W@1236|Gammaproteobacteria,1XJRI@135619|Oceanospirillales 135619|Oceanospirillales S Dicarboxylate transport - - - - - - - - - - - - DctA-YdbH k141_7131_2 1042375.AFPL01000029_gene3446 3.65e-24 92.4 2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,1SCAF@1236|Gammaproteobacteria,46954@72275|Alteromonadaceae 1236|Gammaproteobacteria S YnbE-like lipoprotein ynbE - - - - - - - - - - - Lipoprotein_19 k141_7131_3 1278309.KB907099_gene2535 4.11e-55 174.0 COG3784@1|root,COG3784@2|Bacteria,1N6R1@1224|Proteobacteria,1SC8V@1236|Gammaproteobacteria,1XM2K@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09978 - - - - ko00000 - - - DUF1318 k141_7131_5 1278309.KB907099_gene2533 4.57e-228 632.0 COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,1S150@1236|Gammaproteobacteria,1XJ22@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized protein conserved in bacteria (DUF2219) - - - - - - - - - - - - DUF2219 k141_7131_6 1278309.KB907099_gene2532 0.0 1102.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,1XI9Q@135619|Oceanospirillales 135619|Oceanospirillales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18988_1 1049564.TevJSym_aj00250 1.4e-166 474.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1J4FB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_18988_2 227377.CBU_0138 3.92e-06 48.5 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1JDVB@118969|Legionellales 118969|Legionellales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_4355_1 101852.XP_008085907.1 0.000811 43.1 COG0642@1|root,KOG0519@2759|Eukaryota,39R3Q@33154|Opisthokonta,3NUCH@4751|Fungi,3QP38@4890|Ascomycota,20YGH@147548|Leotiomycetes 4751|Fungi T Phytochrome region - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_2,PHY,Response_reg k141_4355_2 857087.Metme_0270 1.23e-122 362.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XDRI@135618|Methylococcales 135618|Methylococcales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_4355_3 686340.Metal_2690 1.28e-49 162.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XEZ2@135618|Methylococcales 135618|Methylococcales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_8522_1 1266914.ATUK01000013_gene1849 5.44e-21 92.4 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WW6D@135613|Chromatiales 135613|Chromatiales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_18281_1 443152.MDG893_17327 3.3e-81 251.0 COG0811@1|root,COG0811@2|Bacteria 2|Bacteria U bacteriocin transport - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_18281_2 1122197.ATWI01000010_gene933 1.56e-36 128.0 COG0848@1|root,COG0848@2|Bacteria,1RDD8@1224|Proteobacteria 1224|Proteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_18281_3 1122197.ATWI01000010_gene932 2.26e-43 146.0 COG0848@1|root,COG0848@2|Bacteria,1RE9Q@1224|Proteobacteria 1224|Proteobacteria U biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_18281_4 351348.Maqu_0183 7e-43 152.0 COG0810@1|root,COG0810@2|Bacteria,1PEER@1224|Proteobacteria,1RPPU@1236|Gammaproteobacteria,468N3@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - Chalcone_3,TonB_2,TonB_C k141_18281_5 225937.HP15_840 0.0 983.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,4644Y@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1132 ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_18281_6 1318628.MARLIPOL_13169 1.63e-148 422.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RQ6C@1236|Gammaproteobacteria,46D51@72275|Alteromonadaceae 1236|Gammaproteobacteria HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_18281_7 225937.HP15_838 3.02e-142 410.0 COG0614@1|root,COG0614@2|Bacteria,1PEJ1@1224|Proteobacteria,1RNIS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type Fe3 -hydroxamate transport system, periplasmic component fhuD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iAPECO1_1312.APECO1_1833,iEC042_1314.EC042_0152,iECABU_c1320.ECABU_c01660,iECNA114_1301.ECNA114_0143,iECOK1_1307.ECOK1_0155,iECS88_1305.ECS88_0163,iECSF_1327.ECSF_0169,iLF82_1304.LF82_0653,iNRG857_1313.NRG857_00790,iSDY_1059.SDY_0168,iUMN146_1321.UM146_23575 Peripla_BP_2 k141_858_1 1123252.ATZF01000001_gene1545 4.85e-63 213.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,27C0D@186824|Thermoactinomycetaceae 91061|Bacilli M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k141_16888_1 1288826.MSNKSG1_10323 3.59e-76 227.0 COG4259@1|root,COG4259@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4810) - - - - - - - - - - - - DUF4810 k141_16888_2 1288826.MSNKSG1_10328 5.54e-69 208.0 2EBMY@1|root,335N5@2|Bacteria,1N80R@1224|Proteobacteria,1SDM7@1236|Gammaproteobacteria,46C9M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16888_3 1288826.MSNKSG1_10333 7.46e-79 242.0 COG1462@1|root,COG1462@2|Bacteria,1NDU8@1224|Proteobacteria,1RPPY@1236|Gammaproteobacteria,467EW@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in formation of curli polymers csgG - - - - - - - - - - - CsgG k141_2954_1 1439940.BAY1663_02837 1.7e-45 159.0 COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,1RSFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C protein alpha chain nifD - 1.18.6.1 ko:K02586 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - Oxidored_nitro k141_2954_2 379731.PST_1328 1.51e-29 115.0 COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RMV3@1236|Gammaproteobacteria,1Z2HC@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation nifK - 1.18.6.1 ko:K02591 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - DUF3364,Oxidored_nitro k141_4356_1 1278309.KB907102_gene16 1.64e-105 322.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XIEY@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 k141_21744_1 1353537.TP2_07585 5.76e-155 453.0 COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,2TQK6@28211|Alphaproteobacteria,2XMX1@285107|Thioclava 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family poxB - 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 - R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 - - - Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_13417_1 1278309.KB907105_gene1520 7.26e-92 270.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1XK71@135619|Oceanospirillales 135619|Oceanospirillales S ATPase or kinase - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_13417_2 1278309.KB907105_gene1519 7.26e-259 720.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XHXQ@135619|Oceanospirillales 135619|Oceanospirillales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_11357_1 1122970.AUHC01000020_gene2418 2.2e-20 88.6 COG1765@1|root,COG1765@2|Bacteria,1N0BA@1224|Proteobacteria 1224|Proteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC k141_868_3 187272.Mlg_2390 1.32e-16 80.9 COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,1X1VZ@135613|Chromatiales 135613|Chromatiales NU general secretion pathway protein h - - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl k141_868_4 1049564.TevJSym_av00280 6.25e-60 189.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1J6D2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U general secretion pathway protein gspG GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_9206_1 1123247.AUIJ01000001_gene1593 1.32e-16 79.7 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Major facilitator Superfamily MA20_17060 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_9206_2 766499.C357_14369 2e-27 110.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Major facilitator Superfamily narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_2249_1 349124.Hhal_1274 1.23e-31 124.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_2249_2 1123276.KB893258_gene2871 5.66e-17 79.7 COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,47MT0@768503|Cytophagia 976|Bacteroidetes J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k141_3674_1 1134474.O59_002476 1.23e-58 187.0 2D1S3@1|root,32TB8@2|Bacteria,1N262@1224|Proteobacteria,1SFPV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17600_1 1026882.MAMP_00385 2.72e-84 251.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,4604J@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_17600_2 1286106.MPL1_08554 9.55e-50 162.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,460FE@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 k141_13438_1 697282.Mettu_3001 3.18e-40 152.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XDUM@135618|Methylococcales 135618|Methylococcales S Competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_5787_2 1500301.JQMF01000023_gene5578 3.44e-57 185.0 COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,4BD58@82115|Rhizobiaceae 28211|Alphaproteobacteria C Citrate synthase, C-terminal domain - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_14839_1 1123393.KB891331_gene2982 2.51e-17 75.9 2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_14839_3 631362.Thi970DRAFT_04464 1.05e-28 115.0 292F7@1|root,2ZPZF@2|Bacteria,1RGFI@1224|Proteobacteria,1S48P@1236|Gammaproteobacteria,1WY8A@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_158_1 631362.Thi970DRAFT_02329 2.05e-28 115.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_20410_2 580332.Slit_2117 2.35e-76 241.0 COG0475@1|root,COG0475@2|Bacteria,1PK6U@1224|Proteobacteria,2WAEY@28216|Betaproteobacteria,44WJS@713636|Nitrosomonadales 28216|Betaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_15550_1 498761.HM1_1392 9.17e-09 53.5 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia 186801|Clostridia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_15550_2 317025.Tcr_0310 5.08e-72 221.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,460IG@72273|Thiotrichales 72273|Thiotrichales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_16901_1 1278309.KB907101_gene344 4.12e-195 542.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,1RQ8V@1236|Gammaproteobacteria,1XIQ7@135619|Oceanospirillales 135619|Oceanospirillales K Amidohydrolase - - 3.1.1.57 ko:K10221 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R04277 RC03110 ko00000,ko00001,ko01000 - - - Amidohydro_2 k141_16901_2 207954.MED92_10324 1.5e-79 253.0 COG0477@1|root,COG2814@2|Bacteria,1R8QG@1224|Proteobacteria 1224|Proteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_9903_2 203122.Sde_2352 3.03e-23 100.0 COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,1MU1B@1224|Proteobacteria,1SYHX@1236|Gammaproteobacteria,46DIM@72275|Alteromonadaceae 1236|Gammaproteobacteria C 4Fe-4S dicluster domain - - - ko:K07307 ko00920,map00920 - R09501 RC02555 ko00000,ko00001,ko02000 5.A.3.3 - - DmsC,Fer4_11,Fer4_4 k141_11371_1 306537.jk0156 3.46e-07 55.5 COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria,2GNSI@201174|Actinobacteria,22KF1@1653|Corynebacteriaceae 201174|Actinobacteria O Belongs to the sulfur carrier protein TusA family - - - ko:K07112 - - - - ko00000 - - - Sulf_transp,TusA k141_11371_2 1123400.KB904756_gene2655 9.61e-15 72.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_6439_1 1461582.BN1048_02169 1.29e-23 103.0 COG0204@1|root,COG0204@2|Bacteria,1UGYE@1239|Firmicutes,4HFMM@91061|Bacilli,4GYKZ@90964|Staphylococcaceae 91061|Bacilli I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase k141_13439_1 1288494.EBAPG3_1430 1.88e-53 176.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,3720E@32003|Nitrosomonadales 28216|Betaproteobacteria O Ribosomal RNA adenine dimethylase pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_19699_1 1278309.KB907102_gene231 7.68e-95 286.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XIUE@135619|Oceanospirillales 135619|Oceanospirillales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_19699_2 1278309.KB907102_gene230 1.97e-125 358.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1XJ7X@135619|Oceanospirillales 135619|Oceanospirillales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_19699_3 1278309.KB907102_gene229 1.85e-61 189.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1XK9U@135619|Oceanospirillales 135619|Oceanospirillales S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_19699_4 1278309.KB907102_gene228 6.08e-66 224.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XHPB@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_5788_1 396588.Tgr7_0499 7.09e-93 290.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_14840_1 643867.Ftrac_1351 4.05e-63 200.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_3675_1 95619.PM1_0206615 3.69e-61 205.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_870_1 1485544.JQKP01000015_gene2090 3.27e-79 253.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2WD6M@28216|Betaproteobacteria,44WJD@713636|Nitrosomonadales 28216|Betaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_9904_1 1279017.AQYJ01000019_gene1477 2.34e-19 90.5 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,466NG@72275|Alteromonadaceae 1236|Gammaproteobacteria E Allophanate hydrolase subunit 2 - - - - - - - - - - - - CT_A_B k141_18300_1 1278309.KB907099_gene2708 4.65e-129 370.0 COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,1XRVD@135619|Oceanospirillales 135619|Oceanospirillales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_5789_1 317025.Tcr_0435 1.25e-73 234.0 COG4591@1|root,COG4591@2|Bacteria,1RD9H@1224|Proteobacteria,1SZ4B@1236|Gammaproteobacteria 1236|Gammaproteobacteria M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k141_16194_1 27923.ML223523a-PA 1.89e-31 135.0 2BGHS@1|root,2S19H@2759|Eukaryota,3A55C@33154|Opisthokonta,3BRV7@33208|Metazoa 33208|Metazoa S C-terminal domain of apextrin - - - - - - - - - - - - ApeC,VCBS k141_5032_1 1288826.MSNKSG1_13457 5.18e-199 551.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,466I9@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_5032_2 1288826.MSNKSG1_13452 1.21e-88 260.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,467YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) hslR GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K04762 - - - - ko00000,ko03110 - - - S4 k141_5032_3 1288826.MSNKSG1_13447 1.63e-166 465.0 COG0546@1|root,COG0546@2|Bacteria,1QUHZ@1224|Proteobacteria,1T1ZN@1236|Gammaproteobacteria,46D4U@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase (HAD superfamily) - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_5032_4 1288826.MSNKSG1_13442 1.56e-70 213.0 2E7KC@1|root,3322E@2|Bacteria,1NBFM@1224|Proteobacteria,1SDU2@1236|Gammaproteobacteria,46CCM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Multidrug transporter - - - - - - - - - - - - - k141_5032_5 1288826.MSNKSG1_13437 6.44e-198 548.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_5032_6 1288826.MSNKSG1_13432 6.97e-284 775.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria 1236|Gammaproteobacteria I desaturase desA - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase k141_871_2 1279009.ADICEAN_02230 1.67e-11 64.3 COG1752@1|root,COG1752@2|Bacteria,4NISG@976|Bacteroidetes,47P2G@768503|Cytophagia 976|Bacteroidetes S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_11372_1 1121271.AUCM01000016_gene2621 0.000401 50.8 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria 28211|Alphaproteobacteria K ParB domain protein nuclease - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_5790_2 1502770.JQMG01000001_gene296 1.81e-09 55.5 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,2W81A@28216|Betaproteobacteria,2KNAK@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 k141_18301_1 243233.MCA0693 1.71e-153 449.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XDMC@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_9905_1 1123401.JHYQ01000006_gene13 9.37e-38 134.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM cytochrome c oxidase, cbb3-type, subunit II - - - - - - - - - - - - FixO k141_9905_2 582744.Msip34_2139 1.52e-59 194.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KMD1@206350|Nitrosomonadales 206350|Nitrosomonadales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_21761_1 1278309.KB907101_gene716 4.42e-163 475.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XHNV@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_21761_2 1278309.KB907101_gene714 5.26e-160 458.0 COG4129@1|root,COG4129@2|Bacteria,1MV94@1224|Proteobacteria,1RRDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC_2 k141_21761_3 1278309.KB907101_gene713 5.72e-283 780.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHTV@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family aldh1 - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_7337_2 1288826.MSNKSG1_15971 4.55e-242 665.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,464FK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_7337_3 1288826.MSNKSG1_15976 2.69e-178 497.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,465SA@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k141_7337_4 1288826.MSNKSG1_15981 2.05e-163 457.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria,46A4K@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_7337_5 1288826.MSNKSG1_15986 1.74e-05 45.8 COG0683@1|root,COG0683@2|Bacteria,1P7P3@1224|Proteobacteria,1RY95@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_14273_1 1278309.KB907101_gene616 4.67e-243 686.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1XHHD@135619|Oceanospirillales 135619|Oceanospirillales O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_3 k141_14273_2 948565.AFFP02000007_gene370 1.28e-05 44.3 2EJ6D@1|root,33CXK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_14273_3 1278309.KB907101_gene615 1.6e-52 166.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XKNG@135619|Oceanospirillales 135619|Oceanospirillales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_14273_4 1278309.KB907101_gene614 0.0 1466.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1XHZT@135619|Oceanospirillales 135619|Oceanospirillales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_14273_5 1278309.KB907101_gene613 3.72e-129 368.0 COG0694@1|root,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1XHBI@135619|Oceanospirillales 135619|Oceanospirillales C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins nfuA - - ko:K07400 - - - - ko00000 - - - Fe-S_biosyn,NifU k141_14273_6 95619.PM1_0211290 1.78e-151 444.0 COG0534@1|root,COG0534@2|Bacteria,1QTIW@1224|Proteobacteria,1RZ7Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Na driven multidrug efflux pump vcmH - - - - - - - - - - - MatE k141_14273_7 1278309.KB907101_gene612 6.02e-240 664.0 COG4651@1|root,COG4651@2|Bacteria,1QUQS@1224|Proteobacteria,1T21E@1236|Gammaproteobacteria,1XRVC@135619|Oceanospirillales 135619|Oceanospirillales P Sodium hydrogen antiporter - - - - - - - - - - - - Na_H_Exchanger k141_14273_8 1278309.KB907101_gene611 1.08e-204 570.0 COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,1XIKM@135619|Oceanospirillales 135619|Oceanospirillales E glycosyl transferase family - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_14273_9 1278309.KB907101_gene610 3.86e-253 704.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XHSF@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_1784_1 1049564.TevJSym_am00320 4.49e-13 68.2 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1J9H8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E FAD dependent oxidoreductase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_1784_2 748658.KB907312_gene1633 7.61e-28 105.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,1SAXA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P belongs to the Fur family - - - ko:K09826 - - - - ko00000,ko03000 - - - FUR k141_16359_1 1170562.Cal6303_2472 3.62e-40 137.0 COG0645@1|root,COG0645@2|Bacteria,1G714@1117|Cyanobacteria,1HNZ6@1161|Nostocales 1117|Cyanobacteria S Cell division protein ZipA - - - - - - - - - - - - AAA_33 k141_16359_2 1219080.VEZ01S_26_00460 7.03e-73 226.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria,1Y24B@135623|Vibrionales 135623|Vibrionales Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase k141_16359_3 768066.HELO_3433 4.36e-63 196.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria,1XJYN@135619|Oceanospirillales 135619|Oceanospirillales S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase k141_19241_1 930166.CD58_17340 4.25e-45 152.0 COG1028@1|root,COG1028@2|Bacteria,1R6C1@1224|Proteobacteria,1SYUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 k141_19241_2 1415630.U771_16390 2.43e-47 161.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1SIU0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - Sortilin-Vps10 k141_3840_1 880071.Fleli_3092 1.42e-20 92.8 COG0526@1|root,COG0526@2|Bacteria,4PKQH@976|Bacteroidetes,47XYZ@768503|Cytophagia 976|Bacteroidetes CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - - k141_18472_1 1121101.HMPREF1532_00180 2.48e-13 69.3 COG0662@1|root,COG0662@2|Bacteria,4NQUX@976|Bacteroidetes,2G2KV@200643|Bacteroidia,4AW0H@815|Bacteroidaceae 976|Bacteroidetes G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_9376_2 1278309.KB907101_gene590 3.27e-153 434.0 COG1073@1|root,COG1073@2|Bacteria,1NX86@1224|Proteobacteria,1S17M@1236|Gammaproteobacteria,1XRST@135619|Oceanospirillales 135619|Oceanospirillales S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 k141_9376_3 1278309.KB907101_gene589 1.5e-84 250.0 COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,1S62S@1236|Gammaproteobacteria,1XK30@135619|Oceanospirillales 135619|Oceanospirillales Q Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_9376_4 1278309.KB907101_gene588 9.54e-72 219.0 COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,1S5X4@1236|Gammaproteobacteria,1XKVF@135619|Oceanospirillales 135619|Oceanospirillales Q Thioesterase superfamily - - - - - - - - - - - - 4HBT k141_5935_1 1278309.KB907101_gene653 2.2e-49 158.0 2E40W@1|root,32YXP@2|Bacteria,1N9NA@1224|Proteobacteria,1SF8D@1236|Gammaproteobacteria,1XKYS@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5935_2 1278309.KB907101_gene654 2.22e-138 398.0 29FM1@1|root,302IP@2|Bacteria,1RHJK@1224|Proteobacteria,1S8M8@1236|Gammaproteobacteria,1XK3P@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - Ter k141_5935_3 1278309.KB907101_gene655 2.37e-94 279.0 2E62S@1|root,330RV@2|Bacteria,1N7P9@1224|Proteobacteria,1SCEA@1236|Gammaproteobacteria,1XMGM@135619|Oceanospirillales 135619|Oceanospirillales S PilZ domain - - - - - - - - - - - - PilZ k141_5935_4 1278309.KB907101_gene656 3.73e-23 97.8 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XHFB@135619|Oceanospirillales 135619|Oceanospirillales M Lipoprotein releasing system, transmembrane protein lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_5240_1 1288826.MSNKSG1_15372 1.37e-163 483.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,464RK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECs_1301.ECs3167,iG2583_1286.G2583_2820,iZ_1308.Z3542 Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_1068_1 1535422.ND16A_0536 1.22e-33 118.0 COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,1SBZC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD k141_1068_2 1122201.AUAZ01000001_gene2472 7.08e-149 427.0 COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,1SCZY@1236|Gammaproteobacteria,46CYJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_1068_3 1122201.AUAZ01000001_gene2473 0.0 1217.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,4660Y@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit hyuA - 3.5.2.14,3.5.2.9,6.4.1.6 ko:K01469,ko:K01473,ko:K10855 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_1068_4 330084.JNYZ01000058_gene3001 4.81e-09 60.1 COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4E23T@85010|Pseudonocardiales 201174|Actinobacteria EQ PFAM Hydantoinase B oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_20621_1 870187.Thini_3483 3.45e-92 285.0 COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,1RPBI@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the NifD NifK NifE NifN family nifN - - ko:K02592 - - - - ko00000 - - - Oxidored_nitro k141_11530_1 1208321.D104_03795 2.65e-89 277.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHIY@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aldehyde dehydrogenase family - - 1.2.1.39,1.2.1.54,1.2.1.99 ko:K00146,ko:K09472,ko:K12254 ko00330,ko00360,ko00643,ko01100,ko01120,map00330,map00360,map00643,map01100,map01120 M00136 R02536,R02549,R03177,R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_10853_1 1323663.AROI01000002_gene1220 1.4e-48 167.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein k141_10853_2 1266909.AUAG01000010_gene2671 9.74e-91 271.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales 135613|Chromatiales L Belongs to the UPF0758 family - - - ko:K03630 - - - - ko00000 - - - RadC k141_18473_1 697282.Mettu_2638 2.89e-28 118.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XDNX@135618|Methylococcales 135618|Methylococcales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k141_17078_1 1278309.KB907106_gene1226 3.26e-175 504.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales 135619|Oceanospirillales M gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_13614_1 383407.XOC_4261 4.19e-143 422.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1X4KT@135614|Xanthomonadales 135614|Xanthomonadales O Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_15724_1 95619.PM1_0226175 2.63e-18 83.2 COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,1RMES@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Transcriptional regulator modE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K02019 - - - - ko00000,ko03000 - - - HTH_1,TOBE k141_15724_2 666681.M301_1701 2.34e-221 682.0 COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM EAL domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9 k141_15724_3 395494.Galf_1379 2.71e-67 234.0 COG1196@1|root,COG1352@1|root,COG2201@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2WGKT@28216|Betaproteobacteria 28216|Betaproteobacteria NT PAS domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,PAS_10 k141_14989_1 666681.M301_1701 5.74e-78 265.0 COG2202@1|root,COG2203@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM EAL domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9 k141_4567_1 1288826.MSNKSG1_10973 0.0 1491.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,1RQ27@1236|Gammaproteobacteria,465D5@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_4567_2 1288826.MSNKSG1_10978 3.59e-283 776.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narK1 - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_4567_3 1288826.MSNKSG1_10983 0.0 925.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,465S0@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3850 Signal transduction histidine kinase, nitrate nitrite-specific narX GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_1070_1 545276.KB898727_gene532 1.65e-58 196.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_8718_1 506534.Rhein_0626 2.79e-05 47.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WWY8@135613|Chromatiales 135613|Chromatiales NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_8718_2 582744.Msip34_2319 7.14e-96 302.0 COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,2VM72@28216|Betaproteobacteria,2KNN2@206350|Nitrosomonadales 206350|Nitrosomonadales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_8718_3 1190603.AJYD01000004_gene4212 1.38e-18 84.3 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,1XV7I@135623|Vibrionales 135623|Vibrionales H Site-specific DNA-methyltransferase (adenine-specific) dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k141_12942_1 1485544.JQKP01000004_gene521 1.3e-83 260.0 COG1075@1|root,COG1075@2|Bacteria,1NM55@1224|Proteobacteria,2VNDC@28216|Betaproteobacteria,44W8R@713636|Nitrosomonadales 28216|Betaproteobacteria S Alpha/beta hydrolase of unknown function (DUF900) - - - - - - - - - - - - - k141_12942_2 1123054.KB907733_gene3398 1.69e-31 112.0 COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,1WYVF@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF465) - - - ko:K09794 - - - - ko00000 - - - DUF465 k141_5242_1 589865.DaAHT2_2261 2.43e-51 177.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria 1224|Proteobacteria U type II secretion system protein K gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_15725_1 1002340.AFCF01000027_gene1272 4.89e-70 239.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,34EC3@302485|Phaeobacter 28211|Alphaproteobacteria V AcrB/AcrD/AcrF family ttgE - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran k141_11532_1 1278309.KB907104_gene820 1.97e-100 303.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XK0P@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion, TssG - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_1071_1 314231.FP2506_08551 9.67e-24 93.6 COG5453@1|root,COG5453@2|Bacteria,1N7WA@1224|Proteobacteria,2UFN1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Transcriptional activator HlyU hlyU - - - - - - - - - - - HlyU k141_1071_2 1123237.Salmuc_02399 8.04e-23 92.4 2E3EY@1|root,32YDV@2|Bacteria,1N8MQ@1224|Proteobacteria,2UG1Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_1786_1 931627.MycrhDRAFT_3461 2.29e-97 299.0 COG0665@1|root,COG0665@2|Bacteria 2|Bacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - - - - - - - - - - DAO k141_17091_1 999141.GME_16997 2.99e-49 178.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHUM@135619|Oceanospirillales 135619|Oceanospirillales T Double sensory domain of two-component sensor kinase - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_3 k141_18487_1 1049564.TevJSym_av00160 5.34e-122 363.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1J4EK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_13633_1 1101195.Meth11DRAFT_1560 4.61e-18 80.5 COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,2VVQF@28216|Betaproteobacteria,2KMYP@206350|Nitrosomonadales 206350|Nitrosomonadales N PFAM flagellar hook-basal body complex protein FliE fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_13633_2 745411.B3C1_07089 4.47e-13 70.5 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4Q2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_9392_2 314275.MADE_1007090 6.97e-33 124.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,465QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k141_1802_1 202955.BBND01000020_gene2517 3.71e-67 218.0 COG0732@1|root,COG0732@2|Bacteria,1Q4FB@1224|Proteobacteria,1RS7D@1236|Gammaproteobacteria,3NN5F@468|Moraxellaceae 1236|Gammaproteobacteria V Type I restriction modification DNA specificity domain hsdS - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k141_1802_2 1027273.GZ77_19080 3.02e-70 233.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1XN1Y@135619|Oceanospirillales 135619|Oceanospirillales V HsdM N-terminal domain - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_12261_1 1278309.KB907099_gene3121 4.14e-63 201.0 COG2199@1|root,COG2199@2|Bacteria 2|Bacteria T diguanylate cyclase activity - - - - - - - - - - - - GGDEF,PAS_3 k141_12261_2 1278309.KB907099_gene3127 2.58e-222 617.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XIWH@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12261_3 1278309.KB907099_gene3128 7.74e-55 176.0 COG2703@1|root,COG2703@2|Bacteria,1N3PI@1224|Proteobacteria,1SB9K@1236|Gammaproteobacteria,1XKI5@135619|Oceanospirillales 135619|Oceanospirillales P oxygen carrier activity - - - ko:K07216 - - - - ko00000 - - - Hemerythrin k141_12261_4 1232683.ADIMK_0197 2.43e-55 174.0 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,46BHX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA hypA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - ko:K04651 - - - - ko00000,ko03110 - - - HypA k141_12261_5 1485545.JQLW01000005_gene919 1.08e-123 363.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria 1224|Proteobacteria KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG hypB GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010467,GO:0016151,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:1901564 - ko:K04652 - - - - ko00000,ko03110 - - - cobW k141_22006_2 1123247.AUIJ01000004_gene1010 7.13e-09 56.2 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,2TT70@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_1094_1 472759.Nhal_2848 5.08e-97 298.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WW0E@135613|Chromatiales 135613|Chromatiales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_6612_1 349124.Hhal_1697 2.72e-36 126.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Preprotein translocase yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_6612_2 1238450.VIBNISOn1_1550002 1.67e-12 67.4 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XSE8@135623|Vibrionales 135623|Vibrionales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_11538_1 1288826.MSNKSG1_11608 3.94e-184 513.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3118 Thioredoxin domain-containing protein ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_11538_2 1288826.MSNKSG1_11613 0.0 1585.0 COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,469MN@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon2 - 3.4.21.53 ko:K01338,ko:K08675 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002,ko03029 - - - AAA,LON_substr_bdg,Lon_C k141_11538_3 1288826.MSNKSG1_11618 4.47e-119 342.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,466UV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR k141_11538_4 1288826.MSNKSG1_11623 4.31e-203 563.0 COG4783@1|root,COG4783@2|Bacteria,1QXG2@1224|Proteobacteria,1T3B5@1236|Gammaproteobacteria,465CM@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_17,TPR_19 k141_11538_5 1288826.MSNKSG1_11628 4.05e-265 726.0 COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,1RP5V@1236|Gammaproteobacteria,465G7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component braC - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_11538_6 1288826.MSNKSG1_11633 2.41e-207 575.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,4651J@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livH GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - iSFV_1184.SFV_3460,iSF_1195.SF3475,iSFxv_1172.SFxv_3791,iS_1188.S4288 BPD_transp_2 k141_11538_7 1288826.MSNKSG1_11638 6.26e-236 654.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria,464FK@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livM GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - iPC815.YPO3806,iSDY_1059.SDY_3605 BPD_transp_2,DUF3382 k141_394_1 1288826.MSNKSG1_04866 1.66e-112 327.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,4650F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002 QueF,QueF_N k141_394_2 1288826.MSNKSG1_04861 2.12e-176 492.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46426@72275|Alteromonadaceae 1236|Gammaproteobacteria V Transport permease protein yadH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_394_3 1288826.MSNKSG1_04856 2.96e-49 164.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_4656_2 631362.Thi970DRAFT_04935 2.45e-48 155.0 COG2920@1|root,COG2920@2|Bacteria,1RITK@1224|Proteobacteria,1S609@1236|Gammaproteobacteria,1WYM9@135613|Chromatiales 135613|Chromatiales P Part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_18550_1 519989.ECTPHS_09974 2.17e-87 273.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_18550_2 153948.NAL212_1572 5.83e-32 120.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,2W9T1@28216|Betaproteobacteria,374JF@32003|Nitrosomonadales 28216|Betaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA k141_5341_1 870187.Thini_2899 3.66e-118 357.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,460E6@72273|Thiotrichales 72273|Thiotrichales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_11593_2 658187.LDG_7605 2.82e-68 216.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,1JDG6@118969|Legionellales 118969|Legionellales S Glucose-regulated metallo-peptidase M90 mtfA - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_1175_1 1278309.KB907099_gene2801 0.0 1108.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_7419_1 1158182.KB905021_gene822 3.48e-30 115.0 COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,1S4JR@1236|Gammaproteobacteria,1WYSP@135613|Chromatiales 135613|Chromatiales IQ Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2 k141_7419_2 1031711.RSPO_c02971 6.37e-130 387.0 COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2VJR3@28216|Betaproteobacteria,1K3W4@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_7419_3 1266908.AQPB01000027_gene634 7e-20 93.2 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,1WW0H@135613|Chromatiales 135613|Chromatiales S MMPL family - - - - - - - - - - - - MMPL k141_3904_1 1007105.PT7_1506 1.16e-103 316.0 COG0683@1|root,COG0683@2|Bacteria,1QENW@1224|Proteobacteria,2VI4B@28216|Betaproteobacteria,3T42Q@506|Alcaligenaceae 28216|Betaproteobacteria E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_15060_1 1278309.KB907111_gene3369 2.06e-129 378.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHSY@135619|Oceanospirillales 135619|Oceanospirillales CH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent - - - ko:K03184 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R06146,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_15060_2 1278309.KB907111_gene3370 6.8e-65 207.0 2DN40@1|root,32VE9@2|Bacteria,1MZI1@1224|Proteobacteria,1SBSM@1236|Gammaproteobacteria,1XKI6@135619|Oceanospirillales 135619|Oceanospirillales S Phasin protein - - - - - - - - - - - - Phasin_2 k141_15060_3 1278309.KB907111_gene3371 1.13e-147 442.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,1XIUF@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the peptidase M16 family - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_8176_1 697282.Mettu_3480 4.71e-209 614.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_8176_2 697282.Mettu_3479 5.1e-171 485.0 COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1XDK5@135618|Methylococcales 135618|Methylococcales F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_8176_3 519989.ECTPHS_09333 1.22e-79 243.0 COG0535@1|root,COG0535@2|Bacteria,1QUQ6@1224|Proteobacteria,1T20T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_14,Radical_SAM k141_6665_1 159087.Daro_3188 3.36e-07 54.7 2BX44@1|root,32VIR@2|Bacteria,1N2JK@1224|Proteobacteria,2VVHA@28216|Betaproteobacteria,2KXAF@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_18551_1 1288826.MSNKSG1_06028 4.07e-128 376.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,464D2@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3639 ABC-type phosphate phosphonate transport system, permease component phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k141_5989_1 1278309.KB907106_gene1350 8.34e-167 473.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHMY@135619|Oceanospirillales 135619|Oceanospirillales IQ catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_5989_2 1278309.KB907106_gene1349 2.69e-163 460.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1XJJ5@135619|Oceanospirillales 135619|Oceanospirillales I 1-acyl-sn-glycerol-3-phosphate acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_5989_3 1278309.KB907106_gene1348 7.33e-97 283.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XJTA@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC,ThiS k141_5989_4 1278309.KB907106_gene1347 4.4e-223 620.0 COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,1XHR5@135619|Oceanospirillales 135619|Oceanospirillales I Acyltransferase - - - - - - - - - - - - Acyltransferase k141_5989_5 207954.MED92_18358 1.02e-95 288.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XHTC@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_19313_1 485913.Krac_0986 8.68e-200 576.0 COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2G5Z5@200795|Chloroflexi 200795|Chloroflexi C FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Response_reg k141_13718_1 1541065.JRFE01000047_gene3301 6.77e-60 203.0 COG2199@1|root,COG2199@2|Bacteria,1GQQT@1117|Cyanobacteria,3VNND@52604|Pleurocapsales 1117|Cyanobacteria T diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,Response_reg k141_5342_1 754476.Q7A_632 5.65e-97 286.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,460ET@72273|Thiotrichales 72273|Thiotrichales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_5342_2 1458427.BAWN01000015_gene1027 1.59e-24 101.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,4AAVH@80864|Comamonadaceae 28216|Betaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_10192_1 323261.Noc_2595 1.29e-84 255.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1WY1A@135613|Chromatiales 135613|Chromatiales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_10192_2 83406.HDN1F_18920 5.71e-45 156.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1J4IT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675 RsgA_GTPase k141_13034_1 1278309.KB907100_gene2051 4.28e-37 134.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XI42@135619|Oceanospirillales 135619|Oceanospirillales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_13034_2 1278309.KB907100_gene2052 1.03e-67 214.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1XI33@135619|Oceanospirillales 135619|Oceanospirillales NU twitching motility protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_16451_1 261292.Nit79A3_1727 5.28e-156 449.0 COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales 28216|Betaproteobacteria KT PFAM Metal-dependent phosphohydrolase, HD - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,GAF_2,HD k141_4658_1 1121904.ARBP01000003_gene6286 1.06e-12 68.6 COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,47Q2F@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF3078) - - - - - - - - - - - - DUF3078 k141_4658_2 1346330.M472_12160 1.95e-40 147.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INWZ@117747|Sphingobacteriia 976|Bacteroidetes EU peptidase S9 prolyl oligopeptidase active site domain protein pop GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - PD40,Peptidase_S9 k141_18552_1 1209072.ALBT01000009_gene3016 1.12e-47 167.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1FG97@10|Cellvibrio 1236|Gammaproteobacteria C FAD dependent oxidoreductase eryB - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO k141_15072_2 396588.Tgr7_1168 0.000278 43.5 COG2825@1|root,COG2825@2|Bacteria,1NBEV@1224|Proteobacteria,1SDHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane protein (OmpH-like) - - - ko:K06142 - - - - ko00000 - - - OmpH k141_12352_1 1116472.MGMO_152c00080 1.34e-70 228.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XDQU@135618|Methylococcales 135618|Methylococcales G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_7444_1 1049564.TevJSym_ax00090 1.62e-97 303.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1J4ET@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_11608_1 1234364.AMSF01000082_gene2993 3.19e-62 204.0 COG0477@1|root,COG2814@2|Bacteria,1QTW0@1224|Proteobacteria,1T2CZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major Facilitator proP - - ko:K03762 - - - - ko00000,ko02000 2.A.1.6.4 - iJN746.PP_2703 MFS_1,Sugar_tr k141_17173_1 1278309.KB907099_gene2967 5.88e-103 303.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S2MK@1236|Gammaproteobacteria,1XIMH@135619|Oceanospirillales 135619|Oceanospirillales F glutamine amidotransferase - - - - - - - - - - - - GATase k141_17173_2 1122599.AUGR01000015_gene2633 6.62e-158 447.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1XI6A@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter permease - - - ko:K11070,ko:K11074 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - BPD_transp_1 k141_17173_3 1278309.KB907099_gene2965 3.88e-198 552.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1XHK5@135619|Oceanospirillales 135619|Oceanospirillales P binding-protein-dependent transport systems inner membrane component - - - ko:K11075 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 k141_17173_4 1278309.KB907099_gene2964 2.13e-244 676.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XI1W@135619|Oceanospirillales 135619|Oceanospirillales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - - ko:K11076 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - ABC_tran,TOBE_2 k141_17173_5 1278309.KB907099_gene2963 1.57e-124 363.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XHQ6@135619|Oceanospirillales 135619|Oceanospirillales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069,ko:K11073 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 k141_1865_1 985867.AEWF01000001_gene2080 8.95e-36 137.0 COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,2TV5V@28211|Alphaproteobacteria,47F19@766|Rickettsiales 766|Rickettsiales T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,dCache_1 k141_19948_1 396588.Tgr7_3258 1.47e-93 289.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1WX2U@135613|Chromatiales 135613|Chromatiales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer k141_17919_1 1121935.AQXX01000093_gene3413 8.31e-127 368.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XHPG@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_8777_1 859657.RPSI07_2188 2.65e-08 62.8 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria,1K3V3@119060|Burkholderiaceae 28216|Betaproteobacteria L PD-(D/E)XK nuclease superfamily addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_2529_1 207954.MED92_14173 3.13e-202 572.0 COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,1RSD2@1236|Gammaproteobacteria,1XI8I@135619|Oceanospirillales 135619|Oceanospirillales T response regulator - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_13058_1 1408445.JHXP01000017_gene3311 3.65e-55 183.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1JDR2@118969|Legionellales 118969|Legionellales C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_13058_2 207954.MED92_10789 2.43e-28 103.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM98@135619|Oceanospirillales 135619|Oceanospirillales K Cold-shock' - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_13058_3 1278309.KB907111_gene3357 4.39e-63 194.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1XKHN@135619|Oceanospirillales 135619|Oceanospirillales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS k141_13058_4 1278309.KB907111_gene3358 2.45e-82 263.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XHDW@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_10211_1 1278309.KB907104_gene823 2.03e-147 436.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XIYM@135619|Oceanospirillales 135619|Oceanospirillales M Rhs element Vgr protein - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_17174_1 1288826.MSNKSG1_16861 3.29e-55 176.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,466WM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yaeQ - - - - - - - - - - - YaeQ k141_9453_1 413404.Rmag_0010 8.88e-85 262.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1J5A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B k141_1866_1 485918.Cpin_0702 1.35e-09 64.3 COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IPFH@117747|Sphingobacteriia 976|Bacteroidetes M Aspartyl protease - - - - - - - - - - - - Asp_protease_2,PDZ,PDZ_2 k141_15074_1 349124.Hhal_2362 2.73e-66 221.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1WXE4@135613|Chromatiales 135613|Chromatiales J Allophanate hydrolase - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_16467_1 1042375.AFPL01000016_gene19 1.43e-100 311.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4650I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) ychM GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - iSbBS512_1146.SbBS512_E1370 STAS,Sulfate_transp k141_16467_2 264198.Reut_B5701 8.91e-14 66.2 COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,2VXUN@28216|Betaproteobacteria 28216|Betaproteobacteria K PFAM CopG domain protein DNA-binding domain protein - - - - - - - - - - - - RHH_1 k141_16467_3 1278309.KB907104_gene876 1.07e-77 233.0 COG0824@1|root,COG0824@2|Bacteria,1RF7Q@1224|Proteobacteria,1S7PD@1236|Gammaproteobacteria,1XS7Q@135619|Oceanospirillales 135619|Oceanospirillales S Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_2 k141_16467_4 85982.XP_007320237.1 8.35e-20 92.0 COG0500@1|root,KOG4300@2759|Eukaryota,38HFJ@33154|Opisthokonta,3P33C@4751|Fungi,3V293@5204|Basidiomycota,22967@155619|Agaricomycetes 4751|Fungi Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k141_16467_5 1278309.KB907104_gene879 2.3e-96 293.0 COG0330@1|root,COG0330@2|Bacteria,1R93I@1224|Proteobacteria,1RPTI@1236|Gammaproteobacteria,1XINU@135619|Oceanospirillales 135619|Oceanospirillales O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 k141_20689_1 323261.Noc_3069 4.12e-122 372.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales 135613|Chromatiales M HAD-superfamily hydrolase, subfamily IIB - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_17920_2 317619.ANKN01000006_gene840 1.34e-63 209.0 COG1271@1|root,COG1271@2|Bacteria,1G2J8@1117|Cyanobacteria 1117|Cyanobacteria C Cytochrome bd-type quinol oxidase subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iJN678.cydA Cyt_bd_oxida_I k141_4675_1 713586.KB900536_gene206 7.64e-53 178.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S5IM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_4675_2 1232683.ADIMK_3316 3.72e-58 192.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,4671M@72275|Alteromonadaceae 1236|Gammaproteobacteria E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - ko:K06203 - - - - ko00000 - - iJR904.b2413,iYL1228.KPN_02760 EI24 k141_4675_3 393595.ABO_1476 4.97e-12 67.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XNPU@135619|Oceanospirillales 135619|Oceanospirillales P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_22061_2 1278309.KB907100_gene2309 2.57e-192 535.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XHVC@135619|Oceanospirillales 135619|Oceanospirillales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_5365_1 215803.DB30_0862 1.52e-17 82.8 COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,43AGS@68525|delta/epsilon subdivisions,2X5WQ@28221|Deltaproteobacteria,2Z37C@29|Myxococcales 28221|Deltaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 k141_5365_2 391619.PGA1_c23060 1.49e-83 260.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter rbsA - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_7445_1 400668.Mmwyl1_3606 1.37e-51 169.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XJ8C@135619|Oceanospirillales 135619|Oceanospirillales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_7445_2 713586.KB900536_gene1581 5.83e-78 240.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales 135613|Chromatiales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k141_15830_1 765912.Thimo_1742 9.7e-56 184.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1X29Z@135613|Chromatiales 135613|Chromatiales C PFAM Alcohol dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_15830_3 1232683.ADIMK_1219 2.25e-29 107.0 2EANF@1|root,334QY@2|Bacteria,1N8X0@1224|Proteobacteria,1SCTI@1236|Gammaproteobacteria,46BW6@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15830_4 1049564.TevJSym_ak00220 2.27e-91 273.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity ung - 3.2.2.27 ko:K03648,ko:K21929 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k141_15830_5 1123514.KB905899_gene479 8.68e-86 258.0 COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1S99C@1236|Gammaproteobacteria,463J4@72273|Thiotrichales 72273|Thiotrichales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_15830_8 398579.Spea_0978 3.64e-89 276.0 COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,2QASY@267890|Shewanellaceae 1236|Gammaproteobacteria S Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - ko:K03796 - - - - ko00000 - GH73 - Glucosaminidase k141_15830_9 28229.ND2E_0777 1.2e-149 426.0 COG0500@1|root,COG2226@2|Bacteria,1PDVU@1224|Proteobacteria,1RXQY@1236|Gammaproteobacteria,2Q853@267889|Colwelliaceae 1236|Gammaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - - k141_15830_10 523791.Kkor_0894 3.49e-43 143.0 COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,1SCGG@1236|Gammaproteobacteria,1XPZ8@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1272) - - - ko:K09984 - - - - ko00000 - - - DUF1272 k141_15830_11 488538.SAR116_1471 1.49e-93 285.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_15830_12 1123401.JHYQ01000012_gene2931 9e-10 58.9 COG0500@1|root,COG2226@2|Bacteria,1QYZG@1224|Proteobacteria,1T3YI@1236|Gammaproteobacteria,463WC@72273|Thiotrichales 72273|Thiotrichales J ubiE/COQ5 methyltransferase family - - - - - - - - - - - - - k141_13737_1 935567.JAES01000007_gene1904 2.28e-11 63.9 COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1X4PV@135614|Xanthomonadales 135614|Xanthomonadales OP Glutaredoxin - - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin,Rhodanese k141_13737_2 1268239.PALB_7720 1.62e-43 160.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,2PZJJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351 - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - iAPECO1_1312.APECO1_3378,iEC042_1314.EC042_3326,iECOK1_1307.ECOK1_3463 OEP k141_1198_1 1395516.PMO01_12665 2.66e-10 68.9 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_1198_2 412965.COSY_0206 1.26e-11 63.5 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1SDBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_21408_1 686578.AFFX01000003_gene204 1.37e-49 199.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_13060_1 1077972.ARGLB_083_00490 4.82e-25 99.8 COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like polyketide cyclase - - - ko:K06893 - - - - ko00000 - - - SnoaL k141_4745_1 1286106.MPL1_09722 1.43e-140 411.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales 72273|Thiotrichales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_4745_2 1397527.Q670_04875 1.13e-47 156.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XJJ2@135619|Oceanospirillales 135619|Oceanospirillales J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k141_19369_1 1121940.AUDZ01000012_gene829 2.98e-19 88.2 COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,1RY69@1236|Gammaproteobacteria,1XR1D@135619|Oceanospirillales 135619|Oceanospirillales Q Cytochrome P450 - - - - - - - - - - - - p450 k141_15876_1 1288826.MSNKSG1_03856 1.56e-158 444.0 COG0642@1|root,COG2205@2|Bacteria,1R9ZT@1224|Proteobacteria,1S3GX@1236|Gammaproteobacteria,466KE@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c k141_15876_2 1288826.MSNKSG1_03861 0.0 991.0 COG0457@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,1NNCT@1224|Proteobacteria,1RY9B@1236|Gammaproteobacteria,466SV@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Response_reg,TPR_16,TPR_19,TPR_8 k141_15876_3 1288826.MSNKSG1_03866 0.0 2224.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,464E5@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_15876_4 1288826.MSNKSG1_03871 8.54e-123 349.0 2BTTS@1|root,32P1D@2|Bacteria,1RJGR@1224|Proteobacteria,1S6CG@1236|Gammaproteobacteria,46AUW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15876_5 1288826.MSNKSG1_03876 0.0 1118.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,4640T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_15876_6 1288826.MSNKSG1_03881 3.29e-59 182.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,468I1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF4212 k141_15876_7 1288826.MSNKSG1_03886 3.03e-164 459.0 COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,1SBBJ@1236|Gammaproteobacteria,46BA5@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_15876_8 1288826.MSNKSG1_03891 0.0 1251.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,46521@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_15876_9 1288826.MSNKSG1_03896 6.27e-135 382.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,466YR@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Smr k141_12448_2 1288826.MSNKSG1_01238 0.0 994.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,465T6@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_12448_3 351348.Maqu_2271 7.8e-198 550.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,464MX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_12448_4 1288826.MSNKSG1_01223 1.05e-263 731.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,46499@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0608 Single-stranded DNA-specific exonuclease recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_13822_1 1122599.AUGR01000003_gene2010 2.18e-171 496.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RR14@1236|Gammaproteobacteria,1XIH9@135619|Oceanospirillales 135619|Oceanospirillales I Acetyl-coenzyme A synthetase N-terminus - - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_13822_2 1278309.KB907099_gene3081 2.32e-172 485.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria,1XIW6@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_13822_3 207954.MED92_06168 9.64e-211 588.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,1XH8N@135619|Oceanospirillales 135619|Oceanospirillales I enoyl-CoA hydratase - - - - - - - - - - - - ECH_2 k141_13822_4 1278309.KB907099_gene3079 5.98e-63 198.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,1XIQY@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.149 ko:K08299 - - R10675 RC01095 ko00000,ko01000 - - - ECH_1 k141_3360_1 519989.ECTPHS_05621 1.21e-71 228.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1WVV3@135613|Chromatiales 135613|Chromatiales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_558_1 1168065.DOK_12031 2.96e-45 164.0 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,1RR8P@1236|Gammaproteobacteria,1JA4I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_21490_1 519989.ECTPHS_10386 5.55e-77 248.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales 135613|Chromatiales CI TIGRFAM Oxaloacetate decarboxylase, alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_10305_1 1278309.KB907100_gene1798 3.26e-77 240.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XJ9X@135619|Oceanospirillales 135619|Oceanospirillales DM COG0739 Membrane proteins related to metalloendopeptidases nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_15899_1 765912.Thimo_1521 5.37e-18 77.4 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1WZSI@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD k141_15899_2 1121033.AUCF01000015_gene1496 1.87e-22 96.7 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U1PX@28211|Alphaproteobacteria,2JRDE@204441|Rhodospirillales 204441|Rhodospirillales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_14416_1 1288826.MSNKSG1_04691 2.23e-34 123.0 2EQ43@1|root,33HQF@2|Bacteria,1NM67@1224|Proteobacteria,1SIJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14416_2 1288826.MSNKSG1_04686 9.54e-138 390.0 COG4976@1|root,COG4976@2|Bacteria,1QZ2B@1224|Proteobacteria,1T5FM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_14416_3 1288826.MSNKSG1_04681 3.04e-161 451.0 COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria,4671I@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 k141_18023_2 626887.J057_01790 3.08e-22 95.5 COG1403@1|root,COG1403@2|Bacteria,1RHFB@1224|Proteobacteria,1S4HW@1236|Gammaproteobacteria 1236|Gammaproteobacteria V NinG protein - - - - - - - - - - - - NinG k141_9534_2 1121271.AUCM01000003_gene1825 6.33e-93 277.0 COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator, GntR family - - - - - - - - - - - - FCD,GntR k141_1274_1 1288826.MSNKSG1_08648 3.35e-106 318.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_1274_2 1288826.MSNKSG1_08643 0.0 1014.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RQMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria H FOG TPR repeat - - - - - - - - - - - - Methyltransf_25,Methyltransf_31,TPR_1,TPR_11,TPR_12,TPR_16,TPR_8 k141_12449_1 713587.THITH_07265 6.59e-82 251.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1WVX8@135613|Chromatiales 135613|Chromatiales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 k141_17257_1 1166018.FAES_0263 2.71e-50 171.0 COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia 976|Bacteroidetes S PFAM NAD dependent epimerase dehydratase family - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_6739_1 1402135.SUH3_12550 2.47e-05 50.8 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3ZV1H@60136|Sulfitobacter 28211|Alphaproteobacteria P E1-E2 ATPase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_6739_2 187272.Mlg_1310 4.49e-31 116.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WYIF@135613|Chromatiales 135613|Chromatiales S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_22153_1 1323663.AROI01000009_gene3648 2.03e-28 114.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k141_8845_1 1288826.MSNKSG1_12747 0.0 922.0 COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,4660I@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_8845_2 1288826.MSNKSG1_12742 8.07e-145 409.0 2E23Q@1|root,32XB1@2|Bacteria,1N02I@1224|Proteobacteria,1SBCQ@1236|Gammaproteobacteria,4693V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Twin-arginine translocation pathway signal protein - - - - - - - - - - - - - k141_8845_3 1288826.MSNKSG1_12737 1.89e-181 514.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_13131_1 237609.PSAKL28_31080 7.2e-99 302.0 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3385 FOG Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 k141_13131_2 1278309.KB907111_gene3376 2e-125 364.0 COG3672@1|root,COG3672@2|Bacteria,1RKG9@1224|Proteobacteria,1S8MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Periplasmic Protein - - - - - - - - - - - - Transglut_core k141_13131_3 1278309.KB907111_gene3375 2.1e-39 131.0 2EBER@1|root,335FA@2|Bacteria,1NDX3@1224|Proteobacteria,1SEUR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF350 k141_13131_4 1278309.KB907111_gene3374 5.3e-121 350.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1XJJD@135619|Oceanospirillales 135619|Oceanospirillales M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_13131_5 1278309.KB907111_gene3373 1.71e-183 515.0 2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,1XIXA@135619|Oceanospirillales 135619|Oceanospirillales S 5'-nucleotidase - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5-nucleotidase k141_13131_6 1278309.KB907111_gene3372 9.59e-172 483.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1S0VB@1236|Gammaproteobacteria,1XQZ9@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_13824_1 1535422.ND16A_1482 1.39e-49 168.0 COG1714@1|root,COG1714@2|Bacteria,1RFCE@1224|Proteobacteria,1S3V5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S RDD family - - - - - - - - - - - - RDD k141_15150_1 1121033.AUCF01000005_gene5217 3.17e-49 174.0 COG1502@1|root,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2TTM4@28211|Alphaproteobacteria,2JPKW@204441|Rhodospirillales 204441|Rhodospirillales I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc,PLDc_2 k141_5453_1 506534.Rhein_1726 8.93e-19 84.7 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,1WXG1@135613|Chromatiales 135613|Chromatiales S Belongs to the MtfA family - - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 k141_5453_2 765914.ThisiDRAFT_0107 0.0 1001.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1WXKA@135613|Chromatiales 135613|Chromatiales G PFAM Alpha amylase, catalytic - - 2.4.1.4,3.2.1.1,5.4.99.16 ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_5453_3 1123392.AQWL01000006_gene691 1.68e-38 135.0 COG3439@1|root,COG3439@2|Bacteria,1NNMP@1224|Proteobacteria,2VX4A@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_18024_1 661367.LLO_0466 7.44e-18 82.8 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1JC91@118969|Legionellales 118969|Legionellales S Ecdysteroid kinase - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_18024_2 314345.SPV1_07009 2.1e-33 122.0 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_4766_1 1121440.AUMA01000010_gene365 3.32e-20 98.2 COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,43AMJ@68525|delta/epsilon subdivisions,2X61J@28221|Deltaproteobacteria,2M8KF@213115|Desulfovibrionales 28221|Deltaproteobacteria T SMART Metal-dependent phosphohydrolase, HD region - - - - - - - - - - - - DUF3391,HD,HD_5 k141_4766_2 545276.KB898728_gene207 1.28e-18 84.3 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S1QJ@1236|Gammaproteobacteria,1WYXP@135613|Chromatiales 135613|Chromatiales Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - k141_10306_2 1353528.DT23_17205 1.92e-78 244.0 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria 28211|Alphaproteobacteria M epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_8261_1 1288826.MSNKSG1_16841 6.95e-239 662.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T423@1236|Gammaproteobacteria,46DF3@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_8261_2 1288826.MSNKSG1_16836 2.18e-92 279.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_1275_1 1547437.LL06_24715 1.55e-81 257.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,2TT69@28211|Alphaproteobacteria,43IE3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_15900_1 1168067.JAGP01000001_gene1282 1.36e-19 83.6 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,1SDWW@1236|Gammaproteobacteria,462MF@72273|Thiotrichales 72273|Thiotrichales K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_18668_1 1278309.KB907100_gene1867 7.4e-80 245.0 COG0392@1|root,COG0392@2|Bacteria,1RM0R@1224|Proteobacteria,1T0HH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM k141_18668_2 1278309.KB907100_gene1866 4.1e-229 633.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XRZJ@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_18668_3 1278309.KB907100_gene1865 1.47e-287 794.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1XH2A@135619|Oceanospirillales 135619|Oceanospirillales M PFAM glycosyl transferase family 39 - - - - - - - - - - - - PMT,PMT_2 k141_17258_1 1278309.KB907101_gene495 4.89e-126 359.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1XJBH@135619|Oceanospirillales 135619|Oceanospirillales P Zn-ribbon-containing protein involved in phosphonate metabolism - - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_13132_1 247633.GP2143_18356 1.96e-08 53.9 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1J6WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_13132_2 1123401.JHYQ01000006_gene92 9.64e-56 175.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales 72273|Thiotrichales C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin k141_14417_1 452471.Aasi_1765 9.2e-61 206.0 COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia 976|Bacteroidetes E PFAM FAD dependent oxidoreductase thiO - - - - - - - - - - - DAO k141_9535_1 1323663.AROI01000020_gene732 2.68e-90 280.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_9535_2 768671.ThimaDRAFT_2575 3.43e-34 127.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_10307_1 553217.ENHAE0001_2290 7.92e-05 51.2 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Required for the activity of the bacterial periplasmic transport system of putrescine potD GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0019808,GO:0019809,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSbBS512_1146.SbBS512_E2202 SBP_bac_6,SBP_bac_8 k141_16554_1 118163.Ple7327_1594 2.53e-34 150.0 COG2203@1|root,COG3437@1|root,COG3452@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3452@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales 1117|Cyanobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k141_16554_2 1415780.JPOG01000001_gene2281 3.18e-11 63.5 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X3EN@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the peptidase S1C family htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_15901_1 1104324.P186_1471 3.21e-28 110.0 COG2236@1|root,arCOG00040@2157|Archaea,2XPSS@28889|Crenarchaeota 28889|Crenarchaeota F PFAM phosphoribosyltransferase - - - ko:K07101 - - - - ko00000 - - - Pribosyltran k141_8847_1 1502851.FG93_05163 2.47e-22 97.8 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria,3JQZM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Polysaccharide biosynthesis protein - - 5.1.3.10 ko:K12454 ko00520,map00520 - R04266 RC00528 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_6741_1 290398.Csal_2232 1.02e-15 76.3 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XJ25@135619|Oceanospirillales 135619|Oceanospirillales S Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_3362_1 1278309.KB907108_gene1596 3.73e-167 478.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIZ6@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_13826_1 1003200.AXXA_26685 1.15e-31 124.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,3T35M@506|Alcaligenaceae 28216|Betaproteobacteria T chemotaxis protein aer - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH k141_13133_1 522306.CAP2UW1_3171 1.76e-22 101.0 COG0457@1|root,COG0457@2|Bacteria,1QEWV@1224|Proteobacteria,2W8WD@28216|Betaproteobacteria,1KR23@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_18025_1 1049564.TevJSym_aa02290 2.52e-228 654.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1J58G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD k141_18670_1 572477.Alvin_1598 1.06e-73 234.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1WWQD@135613|Chromatiales 135613|Chromatiales H Belongs to the folylpolyglutamate synthase family - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M k141_10308_1 1278309.KB907103_gene1206 9.74e-189 527.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RZ9D@1236|Gammaproteobacteria,1XHTK@135619|Oceanospirillales 135619|Oceanospirillales S Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM k141_19385_1 1278309.KB907099_gene3038 7.12e-66 207.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,1S3X9@1236|Gammaproteobacteria,1XJU6@135619|Oceanospirillales 135619|Oceanospirillales O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k141_19385_2 1278309.KB907099_gene3039 6.93e-131 375.0 COG2304@1|root,COG2304@2|Bacteria,1RA4S@1224|Proteobacteria,1RZNI@1236|Gammaproteobacteria,1XJK8@135619|Oceanospirillales 135619|Oceanospirillales S oxidoreductase activity - - - - - - - - - - - - - k141_19385_3 1278309.KB907099_gene3040 0.0 1008.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,1XHPJ@135619|Oceanospirillales 135619|Oceanospirillales I phospholipid glycerol acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_19385_5 1278309.KB907099_gene3042 3.69e-53 167.0 COG4519@1|root,COG4519@2|Bacteria,1N38K@1224|Proteobacteria,1SAIP@1236|Gammaproteobacteria,1XS90@135619|Oceanospirillales 135619|Oceanospirillales S Winged helix-turn helix - - - - - - - - - - - - HTH_43 k141_21540_1 225937.HP15_2387 8.35e-228 627.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,46A45@72275|Alteromonadaceae 1236|Gammaproteobacteria M Male sterility protein - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_21540_2 1201290.M902_1503 5.91e-53 179.0 COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,43BJ3@68525|delta/epsilon subdivisions,2WRX6@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k141_21540_3 225937.HP15_2389 2.28e-74 236.0 COG0438@1|root,COG0438@2|Bacteria,1NRYT@1224|Proteobacteria 1224|Proteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k141_14473_1 1172562.HCN_0006 7.08e-11 68.6 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2YNNE@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Sulfatase - - - - - - - - - - - - Sulfatase k141_11095_1 1000565.METUNv1_03520 1.69e-19 90.5 COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,2VMV8@28216|Betaproteobacteria,2KVSP@206389|Rhodocyclales 206389|Rhodocyclales V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_19431_1 425104.Ssed_0121 7.35e-06 49.3 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,2Q8MQ@267890|Shewanellaceae 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801 NTP_transf_3 k141_19431_2 713587.THITH_13520 8.25e-55 178.0 COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria,1WY0J@135613|Chromatiales 135613|Chromatiales H molybdopterin-guanine dinucleotide biosynthesis protein mobB - - ko:K03753 - - - - ko00000 - - - MobB k141_19431_3 1123401.JHYQ01000007_gene533 2.24e-78 258.0 COG0303@1|root,COG0746@1|root,COG1763@1|root,COG0303@2|Bacteria,COG0746@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales 72273|Thiotrichales H MoeA N-terminal region (domain I and II) - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MobB,MoeA_C,MoeA_N,NTP_transf_3 k141_17310_2 1207063.P24_11185 3.91e-66 207.0 COG3090@1|root,COG3090@2|Bacteria,1MVKS@1224|Proteobacteria,2U08K@28211|Alphaproteobacteria,2JSXA@204441|Rhodospirillales 204441|Rhodospirillales G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_2675_1 243159.AFE_0075 1.03e-35 126.0 COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,2NDA0@225057|Acidithiobacillales 225057|Acidithiobacillales K MarR family - - - - - - - - - - - - HTH_24 k141_8332_1 1116472.MGMO_42c00080 7.95e-255 702.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1XDMJ@135618|Methylococcales 135618|Methylococcales E PFAM Aminotransferase, class I - - - ko:K14261 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_8332_2 395494.Galf_1821 4.04e-81 251.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,44V1P@713636|Nitrosomonadales 28216|Betaproteobacteria E PFAM aminotransferase class I and II alaA - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_9593_1 551789.ATVJ01000001_gene1072 4e-82 259.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,43WB9@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_8897_5 399741.Spro_4945 3.5e-31 113.0 2E3AH@1|root,32YA0@2|Bacteria,1NBUZ@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k141_14474_1 1163408.UU9_11778 5.99e-98 292.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1X3H6@135614|Xanthomonadales 135614|Xanthomonadales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_17311_1 638303.Thal_0722 9.94e-10 58.5 COG0804@1|root,COG0804@2|Bacteria 2|Bacteria E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iJN746.PP_2845 Amidohydro_1,Urease_alpha k141_17311_2 1121403.AUCV01000019_gene3262 7.91e-49 157.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,42TTS@68525|delta/epsilon subdivisions,2WQS2@28221|Deltaproteobacteria,2MNR8@213118|Desulfobacterales 28221|Deltaproteobacteria E Urease beta subunit ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta k141_6782_1 566466.NOR53_2419 4.6e-94 295.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J8KD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_6782_3 886377.Murru_0629 7.42e-23 102.0 COG1073@1|root,COG1073@2|Bacteria,4NGDK@976|Bacteroidetes,1HX6H@117743|Flavobacteriia 976|Bacteroidetes S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4 k141_6782_4 1121004.ATVC01000029_gene86 1.34e-79 244.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,2KQV1@206351|Neisseriales 206351|Neisseriales O Psort location Cytoplasmic, score pcm2 - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_6782_5 1158165.KB898877_gene1220 1.09e-20 85.1 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_8898_1 1049564.TevJSym_bn00080 7.24e-64 207.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1J5P6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_13875_1 1049564.TevJSym_at00300 9.6e-39 134.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1J6UZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S DJ-1/PfpI family thiJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_13875_2 525898.Sdel_0392 4.12e-32 135.0 COG2199@1|root,COG3614@1|root,COG3614@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T SMART GGDEF domain containing protein - - - - - - - - - - - - CHASE,GGDEF,PAS_3,PAS_9 k141_13875_3 754476.Q7A_527 1.21e-31 129.0 COG0715@1|root,COG0834@1|root,COG5001@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales 72273|Thiotrichales T Diguanylate cyclase phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,NMT1,PAS_9,SBP_bac_3 k141_1341_1 1279017.AQYJ01000025_gene533 7.77e-48 181.0 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_599_2 1117315.AHCA01000011_gene1508 1.49e-47 159.0 COG3184@1|root,COG3184@2|Bacteria,1NGBK@1224|Proteobacteria,1SIUW@1236|Gammaproteobacteria,2Q4W2@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2059) - - - ko:K09924 - - - - ko00000 - - - DUF2059 k141_20771_1 1123368.AUIS01000001_gene2024 6.65e-174 507.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2NC0C@225057|Acidithiobacillales 225057|Acidithiobacillales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_9594_1 870187.Thini_0474 2.69e-29 114.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,46028@72273|Thiotrichales 72273|Thiotrichales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_9594_2 1123399.AQVE01000020_gene1702 1.63e-73 243.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,45ZSE@72273|Thiotrichales 72273|Thiotrichales C dihydrolipoamide dehydrogenase - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim k141_13196_1 1278309.KB907105_gene1405 7.36e-79 235.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,1S3T2@1236|Gammaproteobacteria,1XKV0@135619|Oceanospirillales 135619|Oceanospirillales S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 k141_13196_2 1278309.KB907105_gene1404 2.29e-152 431.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XHT3@135619|Oceanospirillales 135619|Oceanospirillales H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF k141_13196_3 1278309.KB907105_gene1403 1.73e-150 429.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1XJ61@135619|Oceanospirillales 135619|Oceanospirillales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC - 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 k141_13196_4 1278309.KB907105_gene1402 5.73e-173 488.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XHU3@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_6783_1 247633.GP2143_15196 4.13e-16 77.4 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1J4SX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - ko:K03309 - - - - ko00000 2.A.23 - - SDF k141_6783_2 1123053.AUDG01000002_gene2972 0.000862 45.1 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1WWAA@135613|Chromatiales 135613|Chromatiales O peptidylprolyl isomerase - - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 k141_1981_1 1288826.MSNKSG1_06573 7.35e-76 236.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_1981_2 1288826.MSNKSG1_06568 3.92e-214 591.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,464PR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_1981_3 1288826.MSNKSG1_06563 2.53e-265 726.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,46517@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Chorismate_synt k141_18096_1 998088.B565_2545 5.18e-109 318.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1Y3PJ@135624|Aeromonadales 135624|Aeromonadales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_18096_2 1236541.BALL01000010_gene1714 1.58e-07 52.4 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,2QAVI@267890|Shewanellaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0031224,GO:0044425,GO:0044464,GO:0055114,GO:0071944 - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_600_1 1276756.AUEX01000003_gene823 3.93e-35 134.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI09@28216|Betaproteobacteria,4ACRM@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM FAD linked oxidase domain protein - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 k141_13876_1 1249627.D779_4223 8.18e-121 352.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales 135613|Chromatiales K LysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_5503_1 396588.Tgr7_1176 0.0 962.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k141_10365_1 1288826.MSNKSG1_04041 4.63e-88 266.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,4641K@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70 sigma32) rpoS GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_10365_2 1288826.MSNKSG1_04046 2.36e-129 368.0 2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,1S6MA@1236|Gammaproteobacteria,46BPC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 k141_10365_3 1288826.MSNKSG1_04051 1.45e-147 416.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_10365_4 1288826.MSNKSG1_04056 1.38e-163 458.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,464BB@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0031224,GO:0044425,GO:0044464,GO:0055114,GO:0071944 - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_10365_5 1288826.MSNKSG1_04061 2.8e-36 127.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,4672J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_17312_1 377629.TERTU_1663 1.8e-88 271.0 COG3455@1|root,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1RPVN@1236|Gammaproteobacteria,2PPFB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Type VI secretion system protein DotU - - - ko:K11892 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DotU k141_17312_2 1278309.KB907104_gene833 6.34e-34 127.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,1XHSM@135619|Oceanospirillales 135619|Oceanospirillales S type VI secretion protein, VC_A0114 family - - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k141_1342_1 1128912.GMES_2022 8.48e-101 298.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,4655F@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3344 Retron-type reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k141_6143_1 1278309.KB907099_gene2440 1.47e-75 234.0 28I1X@1|root,2Z86C@2|Bacteria,1PPMS@1224|Proteobacteria,1RV76@1236|Gammaproteobacteria,1XJGV@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6143_2 1278309.KB907099_gene2441 3.55e-154 433.0 28H65@1|root,2Z7IN@2|Bacteria,1Q4IY@1224|Proteobacteria,1RZHE@1236|Gammaproteobacteria,1XJ6Z@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6143_3 1278309.KB907099_gene2442 1.08e-208 582.0 28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,1XIER@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3549) - - - - - - - - - - - - DUF3549 k141_6143_4 1278309.KB907099_gene2443 3.44e-131 375.0 arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1XIZW@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_6143_5 1278309.KB907099_gene2444 5.12e-62 197.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_3425_1 1278309.KB907102_gene158 1.33e-164 469.0 COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,1RQBF@1236|Gammaproteobacteria,1XNB4@135619|Oceanospirillales 135619|Oceanospirillales M D-alanyl-D-alanine carboxypeptidase - - - ko:K07262 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S11 k141_3425_2 1278309.KB907102_gene159 1.63e-180 507.0 COG0370@1|root,COG0370@2|Bacteria 2|Bacteria P ferrous iron transmembrane transporter activity - - - - - - - - - - - - Gate k141_4813_1 1278309.KB907102_gene266 0.0 1121.0 COG1196@1|root,COG1196@2|Bacteria,1QUTY@1224|Proteobacteria,1T351@1236|Gammaproteobacteria,1XHM7@135619|Oceanospirillales 135619|Oceanospirillales D DNA replication and repair protein RecF - - - - - - - - - - - - AAA_29,SbcCD_C k141_6784_1 243233.MCA1071 6.63e-80 247.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1XG64@135618|Methylococcales 135618|Methylococcales HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST k141_12514_1 1278309.KB907099_gene2819 5.35e-61 191.0 2E4CH@1|root,32Z7Y@2|Bacteria,1NBRN@1224|Proteobacteria,1SCB9@1236|Gammaproteobacteria,1XM4K@135619|Oceanospirillales 135619|Oceanospirillales S pilus assembly protein, PilZ - - - - - - - - - - - - PilZ k141_12514_2 1278309.KB907099_gene2818 1.02e-40 135.0 28YHZ@1|root,2ZKBX@2|Bacteria,1PAHS@1224|Proteobacteria,1SVWE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12514_3 1278309.KB907099_gene2817 3.61e-82 255.0 COG3016@1|root,COG3016@2|Bacteria,1R5UH@1224|Proteobacteria,1RQXM@1236|Gammaproteobacteria,1XKEH@135619|Oceanospirillales 135619|Oceanospirillales S Haem-binding uptake, Tiki superfamily, ChaN - - - - - - - - - - - - Cofac_haem_bdg k141_4008_1 1288826.MSNKSG1_17001 3.22e-185 525.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,463ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities gppA GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643 HD,Ppx-GppA k141_4008_2 1288826.MSNKSG1_16996 0.0 1080.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,464G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_4008_3 1122197.ATWI01000010_gene1143 1.74e-48 162.0 COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,468Z5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 k141_4008_5 1288826.MSNKSG1_16981 6.42e-157 442.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,466UT@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 mip - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k141_18739_1 1278309.KB907105_gene1458 1.82e-67 228.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales 135619|Oceanospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_18739_2 1278309.KB907105_gene1457 1.02e-49 160.0 2DENC@1|root,2ZNJP@2|Bacteria,1P61E@1224|Proteobacteria,1SUVR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_18739_3 1278309.KB907105_gene1456 4.83e-138 399.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1XIJ0@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate dapC - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_14476_1 1278309.KB907101_gene722 3.92e-159 447.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XH2F@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg k141_13197_1 2340.JV46_11280 3.09e-20 89.4 COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,1SBRN@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_18097_1 1232683.ADIMK_0771 1.27e-106 317.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RP71@1236|Gammaproteobacteria,46A5J@72275|Alteromonadaceae 1236|Gammaproteobacteria C Alcohol dehydrogenase GroES-like domain - - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N k141_20772_1 1469245.JFBG01000058_gene2365 1.92e-19 80.5 COG0291@1|root,COG0291@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_20772_3 1209072.ALBT01000008_gene2858 2.72e-31 120.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1FH45@10|Cellvibrio 1236|Gammaproteobacteria J tRNA synthetases class II core domain (F) pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d k141_8899_1 1288826.MSNKSG1_14152 6.26e-117 347.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,467J0@72275|Alteromonadaceae 1236|Gammaproteobacteria G Sucrose phosphorylase - GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase k141_8899_2 765912.Thimo_0469 2.04e-64 203.0 COG0789@1|root,COG0789@2|Bacteria,1MWN0@1224|Proteobacteria,1RQA6@1236|Gammaproteobacteria,1X0S1@135613|Chromatiales 135613|Chromatiales K MerR family regulatory protein - - - - - - - - - - - - MerR_1 k141_8899_3 765912.Thimo_0470 7.37e-24 91.3 COG0789@1|root,COG0789@2|Bacteria,1NKA7@1224|Proteobacteria,1SHAD@1236|Gammaproteobacteria,1WZM2@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - - - - - - - - - - - k141_20794_1 690597.JH730983_gene134 9.4e-32 118.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1YPG6@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria O Thiol disulfide interchange protein dsbA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k141_5513_1 391595.RLO149_c015690 3.26e-80 260.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2TW4K@28211|Alphaproteobacteria,2P4M8@2433|Roseobacter 28211|Alphaproteobacteria G 4-alpha-glucanotransferase malQ - 2.4.1.25,5.4.99.15 ko:K00705,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000 - GH13,GH77 - Alpha-amylase,Glyco_hydro_77 k141_1360_1 1288826.MSNKSG1_17486 8.41e-227 634.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_1808 PGI k141_1360_2 1288826.MSNKSG1_17481 8.97e-53 169.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,46782@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_11725_1 765914.ThisiDRAFT_1202 1.31e-16 80.1 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1WX2T@135613|Chromatiales 135613|Chromatiales O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_11725_2 756067.MicvaDRAFT_0306 4.38e-19 97.8 COG2114@1|root,COG2114@2|Bacteria,1GGI8@1117|Cyanobacteria,1HGQN@1150|Oscillatoriales 1117|Cyanobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - k141_4827_1 95619.PM1_0205625 1.28e-42 158.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria 1236|Gammaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_4827_2 713586.KB900536_gene1905 7.39e-53 172.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1WY9G@135613|Chromatiales 135613|Chromatiales MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k141_15986_2 765912.Thimo_0096 2.33e-35 129.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1WX1H@135613|Chromatiales 135613|Chromatiales E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth k141_20811_1 1469613.JT55_03830 4.91e-23 91.7 COG5454@1|root,COG5454@2|Bacteria,1N778@1224|Proteobacteria,2UBS2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1467) - - - - - - - - - - - - DUF1467 k141_20811_2 981384.AEYW01000013_gene472 1.12e-57 187.0 COG2981@1|root,COG2981@2|Bacteria,1MWAA@1224|Proteobacteria,2TT6E@28211|Alphaproteobacteria,4NAMA@97050|Ruegeria 28211|Alphaproteobacteria E Etoposide-induced protein 2.4 (EI24) MA20_24505 - - ko:K06203 - - - - ko00000 - - - EI24 k141_10426_1 1122137.AQXF01000001_gene2729 2.67e-62 196.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT k141_11743_1 395493.BegalDRAFT_3416 2.64e-115 339.0 COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,1RYH6@1236|Gammaproteobacteria,45ZY6@72273|Thiotrichales 72273|Thiotrichales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_11743_2 1248232.BANQ01000059_gene1998 1.16e-70 225.0 COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,1RY8Q@1236|Gammaproteobacteria,1XV5H@135623|Vibrionales 135623|Vibrionales P Helix-turn-helix domain - - - - - - - - - - - - HTH_17,PBP_like k141_21578_1 1288826.MSNKSG1_15237 2.08e-170 486.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,465X3@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1030 Membrane-bound serine protease (ClpP class) nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_16647_1 1117958.PE143B_0128430 2.07e-121 358.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the EPSP synthase family. MurA subfamily murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_1385_1 1288826.MSNKSG1_16161 1.89e-110 329.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,467GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase qseC - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_6804_1 1122599.AUGR01000012_gene865 7.9e-112 334.0 COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XNIC@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - Aminotran_1_2,GntR k141_11133_1 1121267.JHZL01000039_gene458 2.23e-18 78.2 2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,42WB2@68525|delta/epsilon subdivisions,2YRYT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - k141_17343_1 1288826.MSNKSG1_17376 2.26e-144 411.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,464U7@72275|Alteromonadaceae 1236|Gammaproteobacteria S stress-induced protein yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - DUF1732,YicC_N k141_17343_2 1288826.MSNKSG1_17381 0.0 1559.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0474 Cation transport ATPase - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_17343_3 1288826.MSNKSG1_17386 5.24e-140 396.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_17343_4 1288826.MSNKSG1_17391 1.01e-41 137.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,468P0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_17343_5 1288826.MSNKSG1_17396 0.0 1380.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,464Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475 ACT_4,HD_4,RelA_SpoT,TGS k141_17343_6 1288826.MSNKSG1_17401 9.06e-83 245.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,4679E@72275|Alteromonadaceae 1236|Gammaproteobacteria J translation initiation inhibitor, yjgF family tdcF - - - - - - - - - - - Ribonuc_L-PSP k141_9641_1 1122201.AUAZ01000007_gene3676 2.47e-40 145.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,46457@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the acetyltransferase family. ArgA subfamily argA GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226 AA_kinase,Acetyltransf_1 k141_9641_2 1278309.KB907100_gene2101 1.72e-267 739.0 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria,1XRSW@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA k141_9641_3 1278309.KB907100_gene2102 5.01e-157 441.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XH96@135619|Oceanospirillales 135619|Oceanospirillales T transcriptional regulator - - - ko:K02483,ko:K07660,ko:K07666 ko01503,ko02020,ko02024,map01503,map02020,map02024 M00444,M00453,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_9641_4 1278309.KB907100_gene2103 4.38e-27 102.0 2DRP1@1|root,33CFN@2|Bacteria,1NJVB@1224|Proteobacteria,1SJBC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY k141_9641_5 1278309.KB907100_gene2104 4.59e-60 192.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1XM01@135619|Oceanospirillales 135619|Oceanospirillales S Outer membrane lipoprotein - - - - - - - - - - - - Rick_17kDa_Anti k141_9641_6 1278309.KB907100_gene2105 2.27e-33 115.0 2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SEIJ@1236|Gammaproteobacteria,1XMEU@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_9641_7 1278309.KB907100_gene2106 5.47e-120 347.0 COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,1S69P@1236|Gammaproteobacteria,1XK9A@135619|Oceanospirillales 135619|Oceanospirillales T helix_turn_helix, cAMP Regulatory protein - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k141_9641_8 1278309.KB907100_gene2107 1.35e-08 53.1 2E8CB@1|root,332QY@2|Bacteria,1NFXB@1224|Proteobacteria,1SD8G@1236|Gammaproteobacteria,1XMFF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20813_2 1026882.MAMP_02247 3.21e-66 213.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_11134_1 1049564.TevJSym_bu00050 1.37e-79 265.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1J52Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_16014_1 998674.ATTE01000001_gene2599 7.47e-40 135.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,460Q2@72273|Thiotrichales 72273|Thiotrichales K nitrogen regulatory protein P-II - - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_16014_2 1042375.AFPL01000046_gene1874 1.37e-235 655.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,4652P@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_16649_1 439235.Dalk_1833 5.37e-50 170.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2MK0W@213118|Desulfobacterales 28221|Deltaproteobacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284,ko:K16074 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3,1.A.35.4 - - CorA k141_10427_2 1288826.MSNKSG1_16591 1.71e-52 166.0 COG3141@1|root,COG3141@2|Bacteria,1N26M@1224|Proteobacteria,1S9G9@1236|Gammaproteobacteria,46CTH@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yebG - - ko:K09918 - - - - ko00000 - - - YebG k141_10427_3 1288826.MSNKSG1_16596 2.26e-60 202.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,465EX@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_5543_1 1244869.H261_03993 1.14e-06 49.3 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2TSKS@28211|Alphaproteobacteria,2JPRB@204441|Rhodospirillales 204441|Rhodospirillales G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11,3.1.3.37 ko:K01086,ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_5543_2 384765.SIAM614_10083 2.09e-231 648.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k141_18775_2 279714.FuraDRAFT_3733 3.19e-20 93.2 COG3103@1|root,COG3103@2|Bacteria,1QVCP@1224|Proteobacteria 1224|Proteobacteria T Sh3 type 3 domain protein - - - - - - - - - - - - - k141_18775_3 1173026.Glo7428_2025 4.5e-84 278.0 COG3322@1|root,COG5001@1|root,COG3322@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS_3,PAS_4,PAS_9 k141_2710_1 1123360.thalar_01051 6.22e-85 262.0 COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2TU4M@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_3464_2 765911.Thivi_0989 1.14e-201 585.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_3464_3 1266925.JHVX01000001_gene2629 7.38e-235 681.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales 28216|Betaproteobacteria IQ AMP-dependent synthetase - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding k141_8959_1 396588.Tgr7_1912 3.06e-60 196.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis k141_11135_2 1288826.MSNKSG1_03036 7.26e-12 61.6 COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,468Y8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the SlyX family slyX - - ko:K03745 - - - - ko00000 - - - SlyX k141_11135_3 298386.PBPRB0666 1.05e-07 53.1 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XT57@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2797) LA2027 - - - - - - - - - - - DUF2797 k141_17344_1 395493.BegalDRAFT_1869 1.43e-18 90.1 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales 72273|Thiotrichales T PFAM response regulator receiver - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_9642_1 1278309.KB907112_gene3332 7.92e-58 191.0 COG3203@1|root,COG3203@2|Bacteria,1NA7U@1224|Proteobacteria,1RPXP@1236|Gammaproteobacteria,1XIHX@135619|Oceanospirillales 135619|Oceanospirillales M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_11745_1 743299.Acife_2300 6.78e-57 191.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria 1236|Gammaproteobacteria L reverse transcriptase - - - - - - - - - - - - RVT_1 k141_6188_2 545276.KB898727_gene296 5e-29 120.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1WXMV@135613|Chromatiales 135613|Chromatiales S membrane - - - - - - - - - - - - DUF2232 k141_6188_3 187272.Mlg_0586 2.54e-58 185.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales 135613|Chromatiales J binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_6188_4 472759.Nhal_3526 2.69e-233 654.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales 135613|Chromatiales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k141_6188_5 1049564.TevJSym_ac00850 8.33e-130 383.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1J56M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440 Ala_racemase_C,Ala_racemase_N k141_6188_6 318167.Sfri_2999 1.78e-05 52.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SAEA@1236|Gammaproteobacteria,2QCK3@267890|Shewanellaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_5544_1 714943.Mucpa_1441 3.33e-40 152.0 COG2911@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,4NHHA@976|Bacteroidetes,1J194@117747|Sphingobacteriia 976|Bacteroidetes MU C-terminal domain of CHU protein family - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3 k141_18776_1 1278309.KB907099_gene2408 1.87e-33 128.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1XJMJ@135619|Oceanospirillales 135619|Oceanospirillales P protein involved in response to NO nnrS - - ko:K07234 - - - - ko00000 - - - NnrS k141_20035_1 870187.Thini_1858 8.09e-191 563.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales 72273|Thiotrichales S Belongs to the UPF0753 family - - - - - - - - - - - - DUF2309 k141_10429_1 1227495.C487_06318 1.16e-30 122.0 COG0438@1|root,arCOG01411@2157|Archaea,2Y8AW@28890|Euryarchaeota,2417S@183963|Halobacteria 183963|Halobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_6189_2 1122604.JONR01000031_gene1258 2.36e-10 56.6 2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,1X8IM@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 k141_21580_1 999549.KI421513_gene2363 1.31e-160 457.0 COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,28255@191028|Leisingera 28211|Alphaproteobacteria E Glycine cleavage T-protein C-terminal barrel domain - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C,SnoaL_2 k141_3466_1 1313301.AUGC01000005_gene251 1.09e-07 53.1 COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes 976|Bacteroidetes J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_3466_2 935840.JAEQ01000004_gene392 2.22e-15 72.8 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,43KM3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_14524_1 1278309.KB907101_gene630 5.61e-88 259.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_14524_2 1278309.KB907101_gene631 5.53e-138 394.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XHX2@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_14524_3 1219072.VHA01S_105_00010 4.25e-34 125.0 COG2963@1|root,COG2963@2|Bacteria,1RGTI@1224|Proteobacteria,1S5H5@1236|Gammaproteobacteria,1XYHW@135623|Vibrionales 135623|Vibrionales L Helix-turn-helix domain - - - - - - - - - - - - HTH_28 k141_14524_4 1219080.VEZ01S_33_00120 1.4e-128 372.0 COG2801@1|root,COG2801@2|Bacteria,1PNRG@1224|Proteobacteria,1RPA5@1236|Gammaproteobacteria,1XV27@135623|Vibrionales 135623|Vibrionales L Integrase core domain - - - - - - - - - - - - HTH_21,rve k141_20831_2 857087.Metme_0360 1.68e-32 120.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1XFBI@135618|Methylococcales 135618|Methylococcales S RDD family - - - - - - - - - - - - RDD k141_660_1 160799.PBOR_26440 1.42e-12 73.2 COG0642@1|root,COG0745@1|root,COG2972@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2972@2|Bacteria,1TRIG@1239|Firmicutes,4HD8X@91061|Bacilli,26QIJ@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase - - - - - - - - - - - - 7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg k141_6224_1 1122194.AUHU01000008_gene3295 4.56e-56 188.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_9658_1 1232683.ADIMK_0072 4.29e-154 448.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_6815_1 1278309.KB907102_gene263 0.0 884.0 COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,1XHD4@135619|Oceanospirillales 135619|Oceanospirillales O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - YcaO k141_6815_2 1278309.KB907102_gene264 1.42e-110 331.0 28KKP@1|root,2ZA5F@2|Bacteria,1PCB9@1224|Proteobacteria,1RPVV@1236|Gammaproteobacteria,1XIQ1@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_2029_1 1278309.KB907103_gene1038 1.26e-21 90.5 COG5581@1|root,COG5581@2|Bacteria,1RJ1B@1224|Proteobacteria,1T0MN@1236|Gammaproteobacteria,1XRQT@135619|Oceanospirillales 135619|Oceanospirillales M Flagellar protein YcgR - - - - - - - - - - - - PilZ,YcgR_2 k141_2029_2 1005395.CSV86_23197 0.000182 46.2 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1YVSF@136845|Pseudomonas putida group 1236|Gammaproteobacteria H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z3582 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_4032_1 1500893.JQNB01000001_gene55 3.96e-15 76.3 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1X4GH@135614|Xanthomonadales 135614|Xanthomonadales NU Flagellar protein export ATPase FliI fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_4032_2 1049564.TevJSym_ac00740 2.18e-40 146.0 COG1317@1|root,COG1317@2|Bacteria,1NBN3@1224|Proteobacteria,1SWWK@1236|Gammaproteobacteria,1J6X3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar biosynthesis type III secretory pathway protein - - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_4032_3 472759.Nhal_2346 3.06e-22 94.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1WWRA@135613|Chromatiales 135613|Chromatiales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_5564_1 1278309.KB907099_gene2450 2.33e-46 152.0 2BY4C@1|root,32XUX@2|Bacteria,1N0C0@1224|Proteobacteria,1SAJV@1236|Gammaproteobacteria,1XM7N@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5564_2 1278309.KB907099_gene2451 4.03e-209 579.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,1XHIM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator metR - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_5564_3 1278309.KB907099_gene2452 3.25e-196 546.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1XH6J@135619|Oceanospirillales 135619|Oceanospirillales E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.9 ko:K00611,ko:K09065 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_17367_1 498211.CJA_0100 6.9e-16 79.7 COG4648@1|root,COG4648@2|Bacteria,1NCP1@1224|Proteobacteria,1SEHE@1236|Gammaproteobacteria,1FI1P@10|Cellvibrio 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - - k141_7627_1 1469613.JT55_02820 5.99e-31 121.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,3FE0U@34008|Rhodovulum 28211|Alphaproteobacteria S TamB, inner membrane protein subunit of TAM complex tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k141_18792_1 744985.HIMB59_00005200 1.56e-76 235.0 COG0600@1|root,COG0600@2|Bacteria,1PGTF@1224|Proteobacteria,2V8ZC@28211|Alphaproteobacteria,4BT0P@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_18792_2 744985.HIMB59_00005210 4.94e-125 361.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,4BPBF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system tauB - 3.6.3.36 ko:K02049,ko:K10831 ko00920,ko02010,map00920,map02010 M00188,M00435 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 - - ABC_tran k141_8988_1 396588.Tgr7_0580 1.13e-63 218.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQ5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_9719_2 880073.Calab_3378 3.29e-14 69.3 COG0700@1|root,COG0700@2|Bacteria,2NPSZ@2323|unclassified Bacteria 2|Bacteria S Nucleoside recognition spmB - - ko:K06374 - - - - ko00000 - - - Gate k141_11813_1 314270.RB2083_3395 5.9e-93 274.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,3ZGGS@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_4095_1 1278309.KB907099_gene2625 1.24e-283 783.0 COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,1XIMX@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD k141_4095_2 1278309.KB907099_gene2626 1.75e-24 92.0 COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,1SHEQ@1236|Gammaproteobacteria,1XMTJ@135619|Oceanospirillales 135619|Oceanospirillales F Anaerobic ribonucleoside-triphosphate reductase - - - - - - - - - - - - NRDD k141_4095_3 1212548.B381_07481 3.03e-08 53.5 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1S4IN@1236|Gammaproteobacteria,1Z19N@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O COG1180 Pyruvate-formate lyase-activating enzyme nrdG - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM k141_6897_1 314345.SPV1_00095 1.41e-35 137.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_6897_2 396588.Tgr7_1961 1.54e-08 54.3 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,1S2D9@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator, ArsR family - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese k141_9720_1 1415779.JOMH01000001_gene1759 3.26e-16 78.6 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1X2YR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_9720_2 472759.Nhal_2797 4.12e-49 159.0 COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales 135613|Chromatiales H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_9720_3 765914.ThisiDRAFT_1270 3.25e-73 227.0 COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1WW3H@135613|Chromatiales 135613|Chromatiales S Converts GTP to 7,8-dihydroneopterin triphosphate folE2 - 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GCHY-1 k141_6899_1 1278309.KB907108_gene1596 4.29e-132 386.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIZ6@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_20132_1 1288826.MSNKSG1_04126 8.43e-61 198.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_20132_2 1288826.MSNKSG1_04131 2.88e-123 352.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA2 - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_20132_3 1288826.MSNKSG1_04136 2.26e-126 362.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,46796@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA k141_4097_1 1049564.TevJSym_au00470 5.62e-69 218.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1J54F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Catabolite gene activator and regulatory subunit of cAMP-dependent protein anr - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_4097_2 1255043.TVNIR_2177 1.73e-13 69.3 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1WXK9@135613|Chromatiales 135613|Chromatiales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_6900_2 1121434.AULY01000012_gene2821 9.89e-19 83.2 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MB8X@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM peptidase M50 - - - - - - - - - - - - Peptidase_M50 k141_9721_1 1288826.MSNKSG1_09728 2.82e-201 565.0 COG1488@1|root,COG1488@2|Bacteria 2|Bacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase k141_6901_1 1423144.Gal_00408 9.64e-106 310.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,34F9Q@302485|Phaeobacter 28211|Alphaproteobacteria C Cytochrome C oxidase, mono-heme subunit/FixO ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_11815_1 270374.MELB17_14316 1.9e-229 641.0 COG3307@1|root,COG3307@2|Bacteria,1QQRX@1224|Proteobacteria,1RTEK@1236|Gammaproteobacteria,46583@72275|Alteromonadaceae 1236|Gammaproteobacteria M O-Antigen ligase - - - - - - - - - - - - Wzy_C k141_11815_2 270374.MELB17_14336 5.9e-82 255.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1SYUH@1236|Gammaproteobacteria,464G2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_11816_1 930169.B5T_01915 1.58e-112 333.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XH2P@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_6903_1 1230343.CANP01000042_gene3185 5.75e-52 180.0 COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1JDR9@118969|Legionellales 118969|Legionellales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_20133_1 1278309.KB907102_gene172 9.43e-180 506.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XI2Z@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase - - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_20133_2 228410.NE1546 2.43e-40 138.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,2VU3K@28216|Betaproteobacteria,373A4@32003|Nitrosomonadales 28216|Betaproteobacteria S SURF4 family - - - ko:K15977 - - - - ko00000 - - - DoxX k141_4100_1 1485545.JQLW01000007_gene643 4.05e-159 454.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria 1224|Proteobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935 Aminotran_5 k141_15280_1 1288826.MSNKSG1_11178 5.31e-268 739.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,4651E@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narM - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_15280_2 1288826.MSNKSG1_11183 2.94e-100 291.0 COG0589@1|root,COG0589@2|Bacteria,1RG5B@1224|Proteobacteria,1S4FD@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp k141_15280_3 1288826.MSNKSG1_11188 0.0 867.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,4652C@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_15280_4 1288826.MSNKSG1_11193 2e-80 239.0 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1RTHT@1236|Gammaproteobacteria,46933@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - SirB k141_15280_5 1288826.MSNKSG1_11198 4.64e-258 710.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,466R8@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein involved in response to NO nnrS - - ko:K07234 - - - - ko00000 - - - NnrS k141_15280_6 1288826.MSNKSG1_11203 1.24e-118 339.0 COG3832@1|root,COG3832@2|Bacteria,1REB4@1224|Proteobacteria,1SBNU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Activator of Hsp90 ATPase 1 family protein - - - - - - - - - - - - AHSA1 k141_15280_7 1288826.MSNKSG1_11208 6.75e-125 355.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,4657R@72275|Alteromonadaceae 1236|Gammaproteobacteria I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_15280_8 1288826.MSNKSG1_11213 2.09e-286 783.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,46552@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_15280_9 1288826.MSNKSG1_11218 2.5e-73 220.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,466QB@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15280_10 1288826.MSNKSG1_11223 1.72e-315 859.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,4652S@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0826 Collagenase and related proteases yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k141_15280_12 1288826.MSNKSG1_11233 0.0 973.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,4658J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component sufB GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 k141_6904_2 425104.Ssed_0198 4.91e-140 414.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,2Q8ZR@267890|Shewanellaceae 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_20134_1 1288826.MSNKSG1_15532 6.2e-139 395.0 COG1018@1|root,COG1018@2|Bacteria,1R5YD@1224|Proteobacteria 1224|Proteobacteria C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 - - 1.6.2.2 ko:K00326 ko00520,map00520 - R00100 - ko00000,ko00001,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_20134_2 1288826.MSNKSG1_03380 1.4e-102 300.0 COG0398@1|root,COG0398@2|Bacteria,1RDZ2@1224|Proteobacteria,1RYPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TVP38 TMEM64 family inner membrane protein ydjZ ydjZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_15281_1 107636.JQNK01000008_gene4053 1.46e-13 72.4 COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,36Z0Q@31993|Methylocystaceae 28211|Alphaproteobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_11,Ubie_methyltran k141_15281_2 870187.Thini_3935 2.86e-32 119.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales 72273|Thiotrichales P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_11817_2 1288826.MSNKSG1_00516 1.49e-153 440.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,469CA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_11817_3 637389.Acaty_c0783 3.13e-124 367.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,2NBT2@225057|Acidithiobacillales 225057|Acidithiobacillales J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_4101_1 857087.Metme_3216 1.37e-235 659.0 COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,1RR54@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_3485_1 1122951.ATUE01000008_gene225 1.02e-79 260.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,3NK8D@468|Moraxellaceae 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_16728_1 63737.Npun_R2439 2.98e-13 74.7 COG2931@1|root,COG2931@2|Bacteria,1G689@1117|Cyanobacteria,1HJNA@1161|Nostocales 1117|Cyanobacteria Q Domain of unknown function (DUF4114) - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Calx-beta,DUF4114,DUF4347,HemolysinCabind,VCBS k141_9758_1 1278309.KB907099_gene2719 9.85e-154 458.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XIGX@135619|Oceanospirillales 135619|Oceanospirillales C formate dehydrogenase fdsA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_7667_1 1485545.JQLW01000007_gene781 7.96e-15 72.8 COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria 1224|Proteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 k141_7667_2 314345.SPV1_04938 3.76e-83 268.0 COG3968@1|root,COG3968@2|Bacteria 2|Bacteria S glutamine synthetase glnN - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C k141_13243_1 713587.THITH_12305 1.86e-57 188.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales 135613|Chromatiales K LysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_20908_1 396588.Tgr7_0580 3.85e-75 247.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQ5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_11849_2 1123393.KB891316_gene1507 1.51e-31 117.0 COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,2VHKR@28216|Betaproteobacteria,1KSKE@119069|Hydrogenophilales 119069|Hydrogenophilales K WYL domain - - - - - - - - - - - - WYL k141_14637_1 998674.ATTE01000001_gene603 1.83e-111 331.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,460C1@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_14637_2 351348.Maqu_3520 5.74e-16 77.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,464E7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0422 IGPS k141_15334_1 980584.AFPB01000142_gene1197 8.93e-65 213.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia,405XU@61432|unclassified Flavobacteriaceae 976|Bacteroidetes I Carboxyl transferase domain accD5 - - - - - - - - - - - Carboxyl_trans k141_15334_2 1237149.C900_01090 1.96e-25 106.0 COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,47MMF@768503|Cytophagia 976|Bacteroidetes Q Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_10456_1 520999.PROVALCAL_02328 2.38e-05 45.8 COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria,1T1HV@1236|Gammaproteobacteria,3Z79X@586|Providencia 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family ybbO GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - - - - - - - - - - adh_short k141_10456_2 1335757.SPICUR_02065 2.43e-46 156.0 COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,1S5RT@1236|Gammaproteobacteria,1X0MN@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1614) - - - - - - - - - - - - DUF1614 k141_20213_1 1123368.AUIS01000022_gene1060 7.92e-118 356.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,2NBV0@225057|Acidithiobacillales 225057|Acidithiobacillales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_4879_1 391615.ABSJ01000054_gene1467 1.2e-64 202.0 COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1JAIZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Peptidoglycan-synthase activator LpoB - - - ko:K07337 - - - - ko00000 - - - LpoB k141_4879_2 653733.Selin_0436 1.68e-41 152.0 COG3014@1|root,COG3014@2|Bacteria 2|Bacteria S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - k141_697_1 870187.Thini_1858 8.38e-55 191.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales 72273|Thiotrichales S Belongs to the UPF0753 family - - - - - - - - - - - - DUF2309 k141_697_3 765912.Thimo_2945 0.000675 42.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,1WWYA@135613|Chromatiales 135613|Chromatiales CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_16729_2 1036674.A28LD_0243 1.22e-26 100.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,2QG9G@267893|Idiomarinaceae 1236|Gammaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_11153_1 1131451.O1K_13853 1.37e-62 212.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the DNA photolyase family phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_6273_1 401526.TcarDRAFT_0245 2.56e-148 431.0 COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,4H1YI@909932|Negativicutes 909932|Negativicutes S Beta-lactamase superfamily domain romA - - - - - - - - - - - Lactamase_B_2 k141_9759_1 323261.Noc_0962 2.03e-130 380.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales 135613|Chromatiales BQ PFAM histone deacetylase superfamily - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl k141_13940_2 582515.KR51_00025170 2.52e-34 132.0 COG0654@1|root,COG0654@2|Bacteria,1FZY0@1117|Cyanobacteria 1117|Cyanobacteria CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family ubiH - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_19517_1 314278.NB231_15168 1.24e-47 168.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA k141_19517_2 765912.Thimo_2949 1.19e-92 296.0 28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,1WW4J@135613|Chromatiales 135613|Chromatiales S Carboxysome shell peptide mid-region - - - - - - - - - - - - CsoS2_M k141_16032_1 1266914.ATUK01000012_gene330 1.6e-06 51.2 2DRAF@1|root,33AYA@2|Bacteria,1NGMJ@1224|Proteobacteria,1SGQI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3293) - - - - - - - - - - - - DUF3293 k141_16032_2 338963.Pcar_2272 3.39e-50 163.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2WMW2@28221|Deltaproteobacteria,43TS9@69541|Desulfuromonadales 28221|Deltaproteobacteria S YaeQ yaeQ - - - - - - - - - - - YaeQ k141_9061_1 68260.JOAY01000007_gene113 2.69e-35 126.0 COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria 201174|Actinobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - ko:K07032 - - - - ko00000 - - - Glyoxalase k141_6970_1 1328313.DS2_09632 4.78e-05 45.4 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_6970_2 555778.Hneap_0656 1.18e-32 124.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales 135613|Chromatiales D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD - - ko:K18778 - - - - ko00000,ko03036 - - - ZapD k141_20909_1 395493.BegalDRAFT_2634 8.07e-121 361.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,45ZQE@72273|Thiotrichales 72273|Thiotrichales M Belongs to the peptidase S1C family - - - ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_15335_1 926556.Echvi_4599 4.25e-58 184.0 COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,47Q0M@768503|Cytophagia 976|Bacteroidetes J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_18820_1 187272.Mlg_0945 3.81e-66 211.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_18820_2 1321781.HMPREF1985_00930 1.42e-08 54.3 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4H64X@909932|Negativicutes 909932|Negativicutes L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_18820_3 1121937.AUHJ01000001_gene499 5.93e-89 261.0 COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM Rubrerythrin - - - - - - - - - - - - Rubrerythrin k141_21604_1 1318628.MARLIPOL_09099 1.06e-24 101.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iNRG857_1313.NRG857_12000 Glucokinase k141_21604_2 232346.JHQL01000001_gene2149 1.48e-307 854.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,1XIH3@135619|Oceanospirillales 135619|Oceanospirillales EG Belongs to the IlvD Edd family edd - 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_21604_3 270374.MELB17_08928 1.39e-25 102.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_18122_2 1288826.MSNKSG1_17980 1.58e-98 288.0 COG2165@1|root,COG2165@2|Bacteria,1QUGH@1224|Proteobacteria,1T1Y8@1236|Gammaproteobacteria,468D3@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG2165 Type II secretory pathway, pseudopilin PulG mshD - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl k141_18122_3 1288826.MSNKSG1_17985 5.78e-169 473.0 COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,1S5ZM@1236|Gammaproteobacteria,468C7@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif mshO - - ko:K12285 - - - - ko00000,ko02044 - - - N_methyl k141_2878_8 1288826.MSNKSG1_12227 0.0 953.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,464VC@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family ybaL - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N k141_2878_9 1288826.MSNKSG1_12232 0.0 909.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,46APC@72275|Alteromonadaceae 1236|Gammaproteobacteria S DinB superfamily - - 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - DinB_2,FGE-sulfatase k141_2878_10 1288826.MSNKSG1_12237 1.12e-291 801.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4650W@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains VP0514 - - ko:K20919 ko05111,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_8,Sigma54_activat k141_2878_11 1288826.MSNKSG1_12242 3.59e-242 667.0 COG3170@1|root,COG4313@1|root,COG3170@2|Bacteria,COG4313@2|Bacteria,1QUSB@1224|Proteobacteria,1T22F@1236|Gammaproteobacteria,466WB@72275|Alteromonadaceae 1236|Gammaproteobacteria CNU Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_11306_4 1288826.MSNKSG1_13612 1.4e-126 365.0 COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,467SN@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc k141_11306_5 1288826.MSNKSG1_13607 1.06e-06 49.7 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,4644F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_16131_1 1453501.JELR01000002_gene1329 4.42e-40 155.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_17520_1 1129794.C427_0296 6.51e-36 131.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,465T4@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family pcaF - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_17520_2 1085623.GNIT_0114 1.57e-34 132.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,464P3@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_1493_1 713586.KB900536_gene2049 7.89e-101 315.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales 135613|Chromatiales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_15486_1 1278309.KB907101_gene415 2.65e-61 193.0 COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,1S77N@1236|Gammaproteobacteria,1XS38@135619|Oceanospirillales 135619|Oceanospirillales J 3'-5' exonuclease - - - - - - - - - - - - DNA_pol_A_exo1 k141_15486_4 1278309.KB907101_gene418 5.51e-177 495.0 COG2207@1|root,COG2207@2|Bacteria,1P1FH@1224|Proteobacteria,1T1HH@1236|Gammaproteobacteria,1XRVW@135619|Oceanospirillales 135619|Oceanospirillales K AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_18 k141_15486_5 1278309.KB907101_gene419 2.77e-241 669.0 COG2223@1|root,COG2223@2|Bacteria,1MW71@1224|Proteobacteria,1RN10@1236|Gammaproteobacteria,1XHR8@135619|Oceanospirillales 135619|Oceanospirillales P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_15486_6 1042375.AFPL01000051_gene145 1.36e-217 612.0 COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,1RN8E@1236|Gammaproteobacteria,464B0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter metT - - - - - - - - - - - Na_H_antiporter k141_15486_7 1278309.KB907101_gene421 1.57e-231 665.0 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1RZ37@1236|Gammaproteobacteria,1XJT9@135619|Oceanospirillales 135619|Oceanospirillales T diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 k141_15486_8 1042375.AFPL01000006_gene2953 4.88e-65 214.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RMIU@1236|Gammaproteobacteria,464FZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF839) uxpB - - ko:K07093 - - - - ko00000 - - - DUF839 k141_7804_1 1288826.MSNKSG1_09338 3.03e-117 342.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_7804_2 1288826.MSNKSG1_09333 7.98e-165 463.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,4656J@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_2200_1 2340.JV46_02580 2.77e-94 287.0 COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,1S76Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_2200_2 312284.A20C1_06796 3.43e-05 47.0 COG3795@1|root,COG3795@2|Bacteria 2|Bacteria F YCII-related domain - - - - - - - - - - - - DoxX_2,YCII k141_4971_1 1123368.AUIS01000007_gene2681 2.74e-86 278.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,2NCDM@225057|Acidithiobacillales 225057|Acidithiobacillales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_20364_1 247634.GPB2148_2778 8.18e-21 86.3 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1J6Z2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_20364_2 1178482.BJB45_20720 3.57e-38 138.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XJPQ@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig k141_19628_1 1288298.rosmuc_00680 1.44e-67 213.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,46NM5@74030|Roseovarius 28211|Alphaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_2901_1 697282.Mettu_3162 2.89e-102 334.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_18951_1 1237149.C900_04805 6.3e-67 216.0 COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia 976|Bacteroidetes KT PFAM Stage II sporulation protein E (SpoIIE) - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE k141_9157_1 633.DJ40_1099 1.88e-134 397.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,41EC4@629|Yersinia 1236|Gammaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_13375_1 795666.MW7_2881 4.03e-150 433.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,1K1VT@119060|Burkholderiaceae 28216|Betaproteobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_7805_1 420662.Mpe_A1225 1.35e-38 147.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_4972_2 247639.MGP2080_12367 5.71e-44 149.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria 1236|Gammaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_15487_2 593750.Metfor_1869 1.07e-20 92.8 COG0714@1|root,arCOG00434@2157|Archaea,2XSZU@28890|Euryarchaeota,2NA7N@224756|Methanomicrobia 224756|Methanomicrobia S PFAM ATPase associated with various cellular activities, AAA_3 - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_3609_1 1123399.AQVE01000010_gene3246 8.27e-25 101.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,46036@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_3609_2 391615.ABSJ01000002_gene467 2.12e-07 53.5 2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_815_1 1245471.PCA10_23730 8.88e-62 190.0 COG5470@1|root,COG5470@2|Bacteria,1RIH6@1224|Proteobacteria,1S63X@1236|Gammaproteobacteria,1YGDK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S NIPSNAP - - - - - - - - - - - - NIPSNAP k141_815_3 225937.HP15_1045 1.73e-50 162.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,467GP@72275|Alteromonadaceae 1236|Gammaproteobacteria C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_9 k141_815_4 349521.HCH_05222 1.93e-207 580.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1RW3Z@1236|Gammaproteobacteria,1XI20@135619|Oceanospirillales 135619|Oceanospirillales O Pyruvate formate lyase-activating protein - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM k141_9853_1 1288826.MSNKSG1_10803 1.86e-131 380.0 COG1639@1|root,COG1639@2|Bacteria,1RJ09@1224|Proteobacteria,1SZ60@1236|Gammaproteobacteria,46CXA@72275|Alteromonadaceae 1236|Gammaproteobacteria T HDOD domain - - - - - - - - - - - - HDOD k141_9853_2 1288826.MSNKSG1_10798 5.05e-298 813.0 COG4399@1|root,COG4399@2|Bacteria,1R42C@1224|Proteobacteria,1RPWG@1236|Gammaproteobacteria,469GI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - - k141_9853_3 1288826.MSNKSG1_10793 3.11e-107 313.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_17522_1 1237149.C900_04538 1.38e-67 230.0 28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_10581_1 228410.NE0635 5.02e-35 125.0 2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,2VT5G@28216|Betaproteobacteria,3733E@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_5721_1 857087.Metme_3218 4.03e-59 194.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_5721_3 1122137.AQXF01000003_gene2130 1.26e-11 65.5 COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,2VFKD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_14775_1 713587.THITH_11125 8.59e-57 187.0 28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,1RMAM@1236|Gammaproteobacteria,1X0EB@135613|Chromatiales 135613|Chromatiales S RES - - - - - - - - - - - - RES k141_14775_2 1265313.HRUBRA_01551 2.85e-38 132.0 COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,1S93Q@1236|Gammaproteobacteria,1J6Z5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384,HTH_3 k141_85_1 396588.Tgr7_1464 2.83e-51 176.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales 135613|Chromatiales S Belongs to the GcvT family - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_11984_2 765910.MARPU_15335 1.68e-22 105.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WW9N@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2,sCache_2 k141_20365_1 2340.JV46_17540 4.84e-71 228.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1J70K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Dimerisation domain of Zinc Transporter fieF - - - - - - - - - - - Cation_efflux,ZT_dimer k141_20365_2 472759.Nhal_0550 9.05e-28 102.0 COG0425@1|root,COG0425@2|Bacteria,1QN0C@1224|Proteobacteria,1TKBV@1236|Gammaproteobacteria,1X1NC@135613|Chromatiales 135613|Chromatiales O Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - TusA k141_20365_3 2340.JV46_17520 5.19e-18 83.2 COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,1T212@1236|Gammaproteobacteria,1J8D6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Thiamine biosynthesis protein (ThiI) - - - - - - - - - - - - ThiI,tRNA_Me_trans k141_816_1 551789.ATVJ01000003_gene369 4.1e-115 343.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,43WJD@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Belongs to the aldehyde dehydrogenase family aldB - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_2902_1 545264.KB898749_gene141 5.51e-79 240.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X0W2@135613|Chromatiales 135613|Chromatiales S PFAM cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans k141_2902_2 29581.BW37_01138 9.17e-25 98.6 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2VM7I@28216|Betaproteobacteria,474AA@75682|Oxalobacteraceae 28216|Betaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids cobO - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR k141_21086_1 1298593.TOL_3100 1.7e-136 402.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XH8A@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_21086_2 472759.Nhal_0333 9.84e-42 139.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1WYWY@135613|Chromatiales 135613|Chromatiales J Sigma 54 modulation protein - - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_21086_3 187272.Mlg_2232 3.49e-16 75.1 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1WYAA@135613|Chromatiales 135613|Chromatiales G PTS IIA-like nitrogen-regulatory protein PtsN - - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_13376_1 1056820.KB900674_gene2494 3e-71 241.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,2PPFG@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria KLT Protein kinase domain stk1 - 2.7.11.1 ko:K08282,ko:K11916,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02044 - - - FGE-sulfatase,Pkinase k141_3610_1 1479237.JMLY01000001_gene1620 7.33e-29 106.0 2E8IW@1|root,332WU@2|Bacteria,1N6NY@1224|Proteobacteria,1SCX1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4295_1 1278309.KB907099_gene3055 1.32e-18 82.8 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1XHW2@135619|Oceanospirillales 135619|Oceanospirillales I enoyl-CoA hydratase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_11308_2 580332.Slit_1358 6.5e-174 494.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,44WHF@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_5722_1 1163409.UUA_03183 2.7e-109 326.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1X3IZ@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_12665_1 472759.Nhal_0341 1.54e-123 359.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1WW98@135613|Chromatiales 135613|Chromatiales Q PFAM ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_11985_1 396588.Tgr7_0090 3.31e-41 152.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,1X08B@135613|Chromatiales 135613|Chromatiales O ResB-like family - - - ko:K07399 - - - - ko00000 - - - ResB k141_1497_1 1163408.UU9_09887 2.81e-117 354.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1X3YJ@135614|Xanthomonadales 135614|Xanthomonadales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_11309_1 857087.Metme_0418 6.31e-60 201.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria,1XG8H@135618|Methylococcales 135618|Methylococcales C Protein of unknown function (DUF3485) - - - - - - - - - - - - DUF3485,Exosortase_EpsH k141_18954_1 981384.AEYW01000003_gene1995 9.72e-45 160.0 COG1574@1|root,COG1574@2|Bacteria,1R53N@1224|Proteobacteria,2VF84@28211|Alphaproteobacteria,4NBCU@97050|Ruegeria 28211|Alphaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_9854_1 2340.JV46_10220 7.08e-31 115.0 2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,1S614@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9854_2 870187.Thini_0392 1.59e-23 94.0 2AAM4@1|root,30ZYM@2|Bacteria,1RFTG@1224|Proteobacteria,1S4UQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF2384 k141_7083_1 1278309.KB907099_gene2903 7.76e-125 358.0 COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,1S341@1236|Gammaproteobacteria,1XQXT@135619|Oceanospirillales 135619|Oceanospirillales T ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 k141_7083_2 1278309.KB907099_gene2902 1.5e-123 354.0 COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,1XJB5@135619|Oceanospirillales 135619|Oceanospirillales K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 k141_7083_3 1278309.KB907099_gene2901 3.21e-204 573.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1XHT8@135619|Oceanospirillales 135619|Oceanospirillales S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase k141_17524_1 95619.PM1_0204690 8.21e-30 119.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_4974_1 292415.Tbd_2360 4.5e-35 133.0 COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales 119069|Hydrogenophilales J Probable RNA and SrmB- binding site of polymerase A - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Archease,HD,PolyA_pol,PolyA_pol_RNAbd k141_4974_2 342113.DM82_5257 2.33e-73 235.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,1K52N@119060|Burkholderiaceae 28216|Betaproteobacteria S tRNA-splicing ligase RtcB rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_12666_1 1002340.AFCF01000066_gene381 1.1e-25 108.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase barA_3 - 2.7.13.1 ko:K05962 - - - - ko00000,ko01000 - - - GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg k141_2903_1 1121479.AUBS01000041_gene665 3.69e-151 439.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2TQZ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA_2 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_10609_1 598467.BrE312_1995 5.28e-07 52.0 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1RY54@1236|Gammaproteobacteria 1236|Gammaproteobacteria O peptidylprolyl isomerase nifM - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase k141_10609_2 395493.BegalDRAFT_0554 4.47e-115 343.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,46052@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP - - - - - - - - - - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_21720_2 1278309.KB907106_gene1277 1.54e-188 529.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1XHBG@135619|Oceanospirillales 135619|Oceanospirillales C COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,FAD_binding_8,Fer2,NAD_binding_1 k141_21720_3 754476.Q7A_2750 4.35e-145 411.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,461GG@72273|Thiotrichales 72273|Thiotrichales S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH k141_13394_1 314278.NB231_15168 3.32e-57 193.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA k141_2219_1 55601.VANGNB10_cI0615 5.17e-45 161.0 COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XUJX@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N k141_261_3 1198232.CYCME_0068 4.91e-19 90.5 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,461X9@72273|Thiotrichales 72273|Thiotrichales NU Type IV fimbrial biogenesis protein PilY1 - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_18396_1 272568.GDI1717 2.82e-13 72.8 2BDIH@1|root,32THT@2|Bacteria,1R3D6@1224|Proteobacteria,2U00X@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_18396_2 1101189.AQUO01000001_gene2942 2.78e-05 44.7 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,2PUU2@265|Paracoccus 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_14908_1 1288826.MSNKSG1_13357 1.94e-133 378.0 COG3637@1|root,COG3637@2|Bacteria,1N3BJ@1224|Proteobacteria,1SB11@1236|Gammaproteobacteria,466S3@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - - - - - - - - - - OMP_b-brl k141_14908_2 1288826.MSNKSG1_13362 9.92e-56 173.0 COG4281@1|root,COG4281@2|Bacteria,1MZPP@1224|Proteobacteria,1SC3P@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyl-coA-binding protein - - - - - - - - - - - - ACBP k141_14908_3 1288826.MSNKSG1_13367 7.36e-64 195.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Phage_integrase k141_14908_5 1288826.MSNKSG1_13377 7.52e-114 327.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,466UU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_14908_6 1288826.MSNKSG1_13382 2.13e-59 184.0 28Y0J@1|root,2ZJW8@2|Bacteria,1NJ4G@1224|Proteobacteria,1SJIG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14908_7 1288826.MSNKSG1_13387 0.0 920.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria,467PM@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_14908_8 1288826.MSNKSG1_13392 2.59e-157 441.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,466JT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_14908_9 1288826.MSNKSG1_13397 1.19e-183 511.0 COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,1RQF9@1236|Gammaproteobacteria,465H8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the hyi family gip - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 k141_14908_10 1288826.MSNKSG1_13402 6.01e-195 543.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,464XV@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases yhaE - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_14908_11 1288826.MSNKSG1_13407 9.06e-197 546.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,464GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_14908_12 1288826.MSNKSG1_13412 2.11e-226 625.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,464N0@72275|Alteromonadaceae 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_14908_13 1288826.MSNKSG1_13417 8.62e-30 111.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,464ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria D ATPase involved in cell division ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_15608_1 754477.Q7C_297 6.38e-38 132.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,460TV@72273|Thiotrichales 72273|Thiotrichales S PFAM L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_15608_2 187272.Mlg_1325 3.72e-71 218.0 COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,1WYAI@135613|Chromatiales 135613|Chromatiales S PFAM Adenylate cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CYTH k141_9294_1 1278309.KB907101_gene561 7.82e-101 300.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1XIE0@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_3080_2 396588.Tgr7_2694 1.71e-55 191.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales 135613|Chromatiales T PFAM Metal-dependent hydrolase HDOD - - - - - - - - - - - - HDOD k141_9982_1 1185876.BN8_03054 8.71e-44 153.0 29R44@1|root,30C5C@2|Bacteria,4NP74@976|Bacteroidetes,47XSE@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_19778_1 1112216.JH594425_gene1793 1.65e-62 206.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PR9I@1224|Proteobacteria,2U1SM@28211|Alphaproteobacteria,2K253@204457|Sphingomonadales 204457|Sphingomonadales C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_4,Pyr_redox_3 k141_7977_1 264201.pc0257 1.39e-07 54.7 COG1121@1|root,COG1121@2|Bacteria,2JFS6@204428|Chlamydiae 204428|Chlamydiae P Part of an ATP-driven transport system CPn0346 CPn0347 CPn0348 CPn0349 for a metal. Probably responsible for energy coupling to the transport system CP_0412 - - ko:K11710 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC_tran k141_7977_2 857087.Metme_2350 1.75e-32 121.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,1XE2F@135618|Methylococcales 135618|Methylococcales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k141_262_1 1124780.ANNU01000003_gene1421 8.93e-23 102.0 COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,47YNN@768503|Cytophagia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k141_9295_1 395493.BegalDRAFT_1381 1.83e-61 211.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales 72273|Thiotrichales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_20536_1 1122599.AUGR01000040_gene68 2.16e-125 364.0 COG1012@1|root,COG1012@2|Bacteria,1MY4N@1224|Proteobacteria,1RR7Y@1236|Gammaproteobacteria,1XJ4S@135619|Oceanospirillales 135619|Oceanospirillales C COG1012 NAD-dependent aldehyde dehydrogenases - - - - - - - - - - - - Aldedh k141_20536_2 1122599.AUGR01000003_gene1987 6.12e-138 395.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RPSX@1236|Gammaproteobacteria,1XI3E@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692,ko:K16880 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00365,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00365,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10210 RC00004,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC01903,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_1692_1 880073.Calab_1707 7.4e-13 68.2 COG1076@1|root,COG1076@2|Bacteria 2|Bacteria O ATPase activator activity djlA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - ko:K04082,ko:K05801,ko:K11159 - - - - ko00000,ko03029,ko03110 - - - DnaJ,TerB k141_13505_1 1504672.669784445 5.51e-24 109.0 COG4719@1|root,COG4719@2|Bacteria,1R87U@1224|Proteobacteria 1224|Proteobacteria S TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11 k141_13505_2 583355.Caka_1294 1.31e-26 105.0 COG4719@1|root,COG4719@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF11 k141_7248_2 1245469.S58_30880 2.71e-17 82.8 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PR9I@1224|Proteobacteria,2U1SM@28211|Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_4,Fer4_6,Pyr_redox_3 k141_5852_1 1046714.AMRX01000001_gene1246 7.33e-66 240.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_2332_1 1288826.MSNKSG1_12172 1.93e-259 724.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,466IR@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain lapD - - - - - - - - - - - EAL,GGDEF,HAMP,LapD_MoxY_N k141_2332_2 1288826.MSNKSG1_12167 4.57e-245 674.0 COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,46486@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2333 k141_968_1 1134474.O59_004079 1.52e-27 111.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S type VI secretion protein - - - ko:K11895 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_TssG k141_968_2 1134474.O59_004078 6.31e-84 265.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type VI secretion vasA - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_10004_2 745411.B3C1_05922 1.01e-19 91.3 COG4968@1|root,COG4968@2|Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02456,ko:K02457,ko:K02458,ko:K02459,ko:K02655,ko:K10926 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - ComP_DUS,N_methyl k141_10004_3 511062.GU3_02150 2.06e-58 197.0 COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria,1S6CB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretion system protein K xpsK - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k141_10004_4 1123073.KB899241_gene3163 1.68e-32 133.0 COG3166@1|root,COG3166@2|Bacteria,1RJTG@1224|Proteobacteria,1S6RT@1236|Gammaproteobacteria,1X4P5@135614|Xanthomonadales 135614|Xanthomonadales NU General secretion pathway protein xpsL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - PilN,T2SSL k141_10004_7 745411.B3C1_05897 1.24e-260 741.0 COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4XH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU General secretion pathway protein D xpsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_12852_1 572477.Alvin_0113 5.62e-52 171.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1WXT6@135613|Chromatiales 135613|Chromatiales I PFAM phosphoesterase PA-phosphatase related - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_19143_1 1123400.KB904769_gene2892 1.45e-69 221.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales 72273|Thiotrichales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_10005_1 1266909.AUAG01000036_gene1128 3.22e-67 211.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WXX0@135613|Chromatiales 135613|Chromatiales M Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_syn_2C,Polysacc_synt_2 k141_21913_1 713586.KB900536_gene120 3.09e-116 341.0 COG2230@1|root,COG2230@2|Bacteria,1QUR4@1224|Proteobacteria,1RP3C@1236|Gammaproteobacteria,1WX7D@135613|Chromatiales 135613|Chromatiales M Methyltransferase - - 2.1.1.157 ko:K18897 ko00260,map00260 - R10061 RC00003,RC03040 ko00000,ko00001,ko01000 - - - Methyltransf_11 k141_13518_1 909943.HIMB100_00006690 8.01e-18 93.2 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,4BP6D@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L PD-(D/E)XK nuclease superfamily addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_17735_1 1461693.ATO10_01155 5.2e-123 360.0 COG0687@1|root,COG0687@2|Bacteria,1MW93@1224|Proteobacteria,2TRJQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0687 Spermidine putrescine-binding periplasmic protein MA20_32195 - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8,TAT_signal k141_10006_1 1123401.JHYQ01000018_gene2408 4.03e-99 301.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46046@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_5866_1 1385420.FRA_38c08840 3.58e-47 153.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,460PX@72273|Thiotrichales 72273|Thiotrichales J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_5866_2 948565.AFFP02000030_gene1188 4.12e-73 221.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1Y8FR@135625|Pasteurellales 135625|Pasteurellales J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 k141_5866_3 580332.Slit_0792 7.76e-93 277.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,44VAX@713636|Nitrosomonadales 28216|Betaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_15626_1 1122599.AUGR01000021_gene3200 5.97e-123 366.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XHTQ@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 k141_15626_2 203122.Sde_3412 7.15e-35 122.0 COG3012@1|root,COG3012@2|Bacteria,1N1DD@1224|Proteobacteria,1S8TK@1236|Gammaproteobacteria,468JD@72275|Alteromonadaceae 1236|Gammaproteobacteria S SEC-C motif - - - - - - - - - - - - SEC-C k141_14225_1 485913.Krac_8941 9.33e-06 48.9 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K03892 - - - - ko00000,ko03000 - - - DUF2087,HTH_20,HTH_5 k141_14225_2 292415.Tbd_1428 2.25e-16 78.6 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase type 11 arsM - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 k141_10774_1 1278309.KB907102_gene6 1.36e-95 291.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XH4N@135619|Oceanospirillales 135619|Oceanospirillales J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL k141_7270_1 1449080.JQMV01000003_gene1676 1.14e-18 81.6 2DQNP@1|root,337TM@2|Bacteria,1WJYU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - k141_12148_1 396588.Tgr7_1915 1.15e-219 616.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_3099_1 396588.Tgr7_0827 2.58e-151 432.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_14923_1 1408254.T458_18055 2.25e-49 160.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,26V63@186822|Paenibacillaceae 91061|Bacilli O Belongs to the glutathione peroxidase family bsaA - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx k141_14923_2 349521.HCH_01171 9.18e-36 128.0 COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria,1XM52@135619|Oceanospirillales 135619|Oceanospirillales Q COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - YiiD_C k141_21914_1 667121.ET1_10_00860 5.85e-39 138.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_21914_2 1026882.MAMP_01427 7.75e-21 90.9 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,460VI@72273|Thiotrichales 72273|Thiotrichales D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD - - ko:K18778 - - - - ko00000,ko03036 - - - ZapD k141_9319_1 1049564.TevJSym_ax00320 2.77e-73 247.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3 k141_8006_2 1173028.ANKO01000199_gene3517 7.09e-13 69.7 COG5002@1|root,COG5002@2|Bacteria,1G009@1117|Cyanobacteria,1H8TV@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_10007_1 1278309.KB907106_gene1365 2.22e-09 57.8 COG4726@1|root,COG4726@2|Bacteria 2|Bacteria NU Pilus assembly protein PilX pilX - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX,PilX_N k141_10007_2 748280.NH8B_3737 1.59e-14 79.0 COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,2KQFG@206351|Neisseriales 206351|Neisseriales NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 k141_8639_1 1158762.KB898039_gene1706 3.3e-97 323.0 COG0642@1|root,COG0683@1|root,COG0745@1|root,COG5002@1|root,COG0683@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Peripla_BP_6,Response_reg k141_8639_2 740709.A10D4_00670 1.79e-43 145.0 COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,2QGYU@267893|Idiomarinaceae 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_8639_3 1266914.ATUK01000018_gene635 5.7e-87 257.0 28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,1SEW0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8639_4 1249627.D779_0183 7.68e-23 88.2 2E4KB@1|root,32ZFA@2|Bacteria,1N6R9@1224|Proteobacteria,1SFP8@1236|Gammaproteobacteria,1WZH8@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_8639_6 713587.THITH_01425 1.74e-83 250.0 COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales 135613|Chromatiales O Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - - k141_8639_7 1158756.AQXQ01000012_gene1997 2.36e-70 214.0 2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,1S4CA@1236|Gammaproteobacteria,1WY9U@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_2353_1 697282.Mettu_3480 1.3e-272 783.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_983_1 1288826.MSNKSG1_00431 1.75e-110 320.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,46745@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 ko:K00969,ko:K01488 ko00230,ko00760,ko01100,ko05340,map00230,map00760,map01100,map05340 M00115 R00137,R01560,R02556,R03005 RC00002,RC00477 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0733,iJN746.PP_4810,iPC815.YPO2607,iSbBS512_1146.SbBS512_E0612 CTP_transf_like k141_983_2 1288826.MSNKSG1_00426 7.68e-292 798.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,464S8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280 Aldedh k141_983_3 1288826.MSNKSG1_00421 1.65e-220 610.0 COG2199@1|root,COG3706@2|Bacteria,1NFY2@1224|Proteobacteria,1SP7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_983_4 1288826.MSNKSG1_00416 1.49e-225 623.0 COG2199@1|root,COG3706@2|Bacteria,1NV9M@1224|Proteobacteria,1SNI2@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF k141_983_5 1288826.MSNKSG1_00411 0.0 917.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,468WP@72275|Alteromonadaceae 1236|Gammaproteobacteria I membrane-associated protein - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2,SNARE_assoc k141_13676_4 1288826.MSNKSG1_01498 1.41e-210 582.0 COG0583@1|root,COG0583@2|Bacteria,1NYPZ@1224|Proteobacteria,1S0MX@1236|Gammaproteobacteria,467KP@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_13676_5 1288826.MSNKSG1_01503 2.4e-102 305.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,464P2@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases HA62_10695 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_7380_1 1282356.H045_18350 5.69e-40 152.0 COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YNE4@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3 k141_18511_2 1278309.KB907113_gene3322 2.32e-142 404.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1XH9B@135619|Oceanospirillales 135619|Oceanospirillales J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_18511_3 1278309.KB907113_gene3323 7.83e-99 288.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XJFF@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_12997_1 314271.RB2654_02269 1.26e-51 176.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_17867_2 1089552.KI911559_gene1778 1.23e-58 197.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2TQVA@28211|Alphaproteobacteria,2JQR0@204441|Rhodospirillales 204441|Rhodospirillales U Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_15039_1 765912.Thimo_1207 2.4e-124 365.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1WWET@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class I and II - - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_11567_1 1198232.CYCME_2424 5.77e-09 55.5 COG0316@1|root,COG0316@2|Bacteria,1RFIX@1224|Proteobacteria,1S3SB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the HesB IscA family - - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn k141_11567_2 1158292.JPOE01000005_gene285 3.11e-21 87.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,1KM13@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX - - - - - - - - - - - Iron_traffic k141_16415_2 472759.Nhal_0708 1.78e-68 224.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales 135613|Chromatiales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_12298_2 1123053.AUDG01000052_gene1914 1.62e-26 119.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1WWWM@135613|Chromatiales 135613|Chromatiales O PFAM peptidase M48 Ste24p - - - - - - - - - - - - Peptidase_M48 k141_14314_1 1056512.D515_00995 2.94e-100 304.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XW26@135623|Vibrionales 135623|Vibrionales S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb k141_7381_1 1278309.KB907104_gene815 4.33e-108 327.0 COG3515@1|root,COG3515@2|Bacteria,1MWDQ@1224|Proteobacteria,1RQXI@1236|Gammaproteobacteria,1XMPX@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ vasJ - - ko:K11910 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - ImpA_N,T6SS_VasJ k141_12998_1 59689.Al_scaffold_0002_944 2.28e-121 349.0 COG1290@1|root,KOG4663@2759|Eukaryota,37QS7@33090|Viridiplantae,3GHBB@35493|Streptophyta 35493|Streptophyta C cytochrome b6 petB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035 - ko:K02635 ko00195,ko01100,map00195,map01100 M00162 - - ko00000,ko00001,ko00002,ko00194 - - - Cytochrome_B k141_15781_1 1026882.MAMP_03131 7.11e-189 538.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales 72273|Thiotrichales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_4622_1 318586.Pden_3973 5.84e-96 285.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,2PVBT@265|Paracoccus 28211|Alphaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_15040_1 765911.Thivi_4550 1.5e-38 143.0 COG0501@1|root,COG4969@1|root,COG0501@2|Bacteria,COG4969@2|Bacteria,1R47C@1224|Proteobacteria,1RPRU@1236|Gammaproteobacteria,1X0GS@135613|Chromatiales 135613|Chromatiales O PFAM Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_10905_1 1112204.GPOL_c09860 1.16e-19 88.6 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4GASI@85026|Gordoniaceae 201174|Actinobacteria L Transposase and inactivated derivatives IS30 family - - - - - - - - - - - - HTH_38,rve k141_9419_1 1202962.KB907157_gene3586 7.66e-56 182.0 COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,1S449@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM cytoplasmic chaperone TorD family protein - - - - - - - - - - - - Nitrate_red_del k141_9419_2 666684.AfiDRAFT_3708 5.48e-34 133.0 COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,2TS71@28211|Alphaproteobacteria,3JSPD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4,Fer4_7 k141_3874_1 223926.28805339 5.86e-79 247.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XU2Y@135623|Vibrionales 135623|Vibrionales G Belongs to the pyruvate kinase family pykF - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_8153_1 1288826.MSNKSG1_09978 3.04e-288 819.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,463XX@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_434_1 713587.THITH_16505 7.5e-72 232.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_21358_1 1268635.Loa_01976 2.88e-08 53.5 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1JG2Z@118969|Legionellales 118969|Legionellales S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_21358_2 1278309.KB907100_gene1800 2.44e-54 177.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XJ7N@135619|Oceanospirillales 135619|Oceanospirillales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_2494_1 1121406.JAEX01000015_gene574 1.29e-27 113.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales 28221|Deltaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,sCache_3_2 k141_2494_2 391615.ABSJ01000059_gene2174 6.95e-218 612.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1J4CY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k141_11568_1 590409.Dd586_3094 1.01e-32 118.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,2JDWH@204037|Dickeya 1236|Gammaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 k141_11568_2 247633.GP2143_08094 2.2e-71 230.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1J571@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_12299_2 1278309.KB907107_gene1658 1.17e-90 271.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1XJB3@135619|Oceanospirillales 135619|Oceanospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_17869_1 225937.HP15_1349 6.02e-07 50.1 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,4680U@72275|Alteromonadaceae 1236|Gammaproteobacteria M Secretion protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3 k141_17869_2 1121374.KB891586_gene2533 7.64e-73 228.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter ybhF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_5303_2 1026882.MAMP_02004 1.72e-133 387.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,4609Z@72273|Thiotrichales 72273|Thiotrichales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_9420_2 1049564.TevJSym_aj00660 7e-75 228.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1J6CP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P PhnA domain phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_15041_1 1101195.Meth11DRAFT_1979 1.52e-07 52.4 COG1668@1|root,COG1668@2|Bacteria,1QYVE@1224|Proteobacteria,2VWEI@28216|Betaproteobacteria,2KM8A@206350|Nitrosomonadales 206350|Nitrosomonadales CP ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 k141_15041_2 243233.MCA3076 9.95e-19 87.4 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1XEHX@135618|Methylococcales 135618|Methylococcales N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux k141_4623_1 467661.RKLH11_3026 2.7e-42 147.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,2U6DE@28211|Alphaproteobacteria,3ZH8C@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S SNARE associated Golgi protein merA_1 - - - - - - - - - - - SNARE_assoc k141_12999_1 640512.BC1003_2665 9.44e-73 246.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,1K2UW@119060|Burkholderiaceae 28216|Betaproteobacteria E aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_1139_2 1116472.MGMO_120c00610 1.17e-127 374.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XESU@135618|Methylococcales 1224|Proteobacteria S associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_1821_1 1288826.MSNKSG1_04661 4.47e-70 211.0 COG4454@1|root,COG4454@2|Bacteria,1QTWM@1224|Proteobacteria,1T2G6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 k141_1821_2 1288826.MSNKSG1_04656 4.48e-192 533.0 COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,1S4R0@1236|Gammaproteobacteria 1236|Gammaproteobacteria P FTR1 family iron permease efeU - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_1821_3 1288826.MSNKSG1_04651 7.97e-186 525.0 COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,1RNU6@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0348 Polyferredoxin - - - - - - - - - - - - Fer4_5 k141_15783_1 1122176.KB903565_gene3328 4.22e-119 366.0 COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes 976|Bacteroidetes C Molybdopterin oxidoreductase - - 1.7.2.3,1.8.5.5 ko:K07812,ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.4,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_17119_1 1288826.MSNKSG1_06488 1.11e-53 175.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,468K7@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria dedD - - ko:K03749 - - - - ko00000 - - - SPOR k141_17119_2 1288826.MSNKSG1_06483 2.15e-121 348.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,467N8@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein, required for colicin V production cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V k141_17119_3 1288826.MSNKSG1_06478 0.0 1011.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,464VT@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125 GATase_6,Pribosyltran k141_17119_4 1288826.MSNKSG1_06473 5.95e-83 255.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,464GC@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - 4.4.1.11 ko:K01761,ko:K10764 ko00270,ko00450,ko00920,ko01100,map00270,map00450,map00920,map01100 - R00654,R01288,R04770 RC00020,RC00196,RC00348,RC01209,RC01210,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_8155_1 546274.EIKCOROL_02241 1.28e-29 112.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,2KQMA@206351|Neisseriales 206351|Neisseriales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA gidB - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_8155_2 1397527.Q670_03400 2.23e-09 58.2 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1XHS4@135619|Oceanospirillales 135619|Oceanospirillales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_10150_1 1288826.MSNKSG1_03690 2.27e-92 294.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,4641E@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M16 family ptrA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_10150_2 1288826.MSNKSG1_03685 5.92e-147 414.0 COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,1S971@1236|Gammaproteobacteria,468UT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09931 - - - - ko00000 - - - DUF2064 k141_10150_3 1288826.MSNKSG1_03680 3.96e-161 452.0 COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria,467G5@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_10150_4 1288826.MSNKSG1_03670 5.46e-158 443.0 COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,1T268@1236|Gammaproteobacteria,466KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0421 Spermidine synthase - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth k141_10150_5 1288826.MSNKSG1_03665 0.0 1064.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4647C@72275|Alteromonadaceae 1236|Gammaproteobacteria P Sulfate permease family sulP - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_10150_6 1288826.MSNKSG1_03660 6.02e-212 585.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,464NE@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases blh - - - - - - - - - - - Lactamase_B k141_12301_1 246200.SPOA0017 1.65e-63 201.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,4NB9N@97050|Ruegeria 28211|Alphaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k141_436_1 290400.Jann_2772 1.05e-37 140.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TX00@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator superfamily - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 k141_2495_2 945543.VIBR0546_18717 8.57e-22 90.1 2BJRX@1|root,32E3Y@2|Bacteria,1Q85U@1224|Proteobacteria,1RXTJ@1236|Gammaproteobacteria,1XYAX@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4156) - - - - - - - - - - - - DUF4156 k141_2495_3 977880.RALTA_B2190 4.94e-38 144.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae 28216|Betaproteobacteria I Phospholipase D Transphosphatidylase - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_7382_1 1123247.AUIJ01000012_gene844 8.19e-06 47.8 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_7400_3 519989.ECTPHS_07416 2.62e-68 217.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales 135613|Chromatiales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_5325_1 519989.ECTPHS_00495 3.3e-35 130.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales 135613|Chromatiales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_5325_2 1121405.dsmv_0915 8.03e-15 70.9 COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MKE0@213118|Desulfobacterales 28221|Deltaproteobacteria F NUDIX domain - - 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000,ko03400 - - - NUDIX k141_5986_1 375286.mma_1357 4.88e-20 88.2 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,472NZ@75682|Oxalobacteraceae 28216|Betaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15355 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_5986_2 1226994.AMZB01000091_gene865 3.99e-39 137.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1YF26@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria IQ KR domain fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710 adh_short_C2 k141_13015_1 1278309.KB907099_gene3063 2.46e-25 101.0 COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,1SYJD@1236|Gammaproteobacteria,1XHTG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_13015_2 1278309.KB907099_gene3064 8.9e-72 226.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XHD8@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_449_1 713586.KB900536_gene929 2.03e-34 142.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales 135613|Chromatiales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_449_2 187272.Mlg_0318 2.04e-41 146.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1WXMF@135613|Chromatiales 135613|Chromatiales O PFAM Thioredoxin - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_10925_1 1123501.KB902310_gene67 1.37e-39 145.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria 28211|Alphaproteobacteria FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA k141_10925_2 1123360.thalar_01197 4.2e-85 271.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_1160_1 686340.Metal_2096 2.02e-159 461.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XEM6@135618|Methylococcales 135618|Methylococcales F Thymidine phosphorylase - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_12324_1 571166.KI421509_gene1882 3.79e-78 244.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_17139_1 1215092.PA6_017_00380 3.15e-27 103.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,1YE4V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_13700_2 1121374.KB891578_gene3253 8.07e-76 237.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S3CB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 k141_13700_3 236097.ADG881_2450 5.42e-87 262.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1XH39@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_15809_1 1288484.APCS01000018_gene1964 1.99e-84 261.0 COG0657@1|root,COG0657@2|Bacteria 2|Bacteria I acetylesterase activity - - - - - - - - - - - - Abhydrolase_3 k141_22045_1 396588.Tgr7_0689 3.18e-55 184.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S2ZF@1236|Gammaproteobacteria,1X2PF@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - GGDEF k141_11578_1 1278309.KB907104_gene910 0.0 881.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XH9A@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO k141_11578_2 1278309.KB907104_gene911 6.91e-146 424.0 COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1XHGT@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_13162_4 1288826.MSNKSG1_05346 9.91e-120 343.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,4670B@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325 CDP-OH_P_transf k141_13162_5 1288826.MSNKSG1_05341 0.0 1206.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,4644T@72275|Alteromonadaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_13162_6 1288826.MSNKSG1_05336 6.6e-147 414.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,466D5@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain gacA - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_13162_8 1288826.MSNKSG1_05326 3.7e-132 377.0 COG1296@1|root,COG1296@2|Bacteria,1RG4P@1224|Proteobacteria,1T05Q@1236|Gammaproteobacteria,46AUP@72275|Alteromonadaceae 1236|Gammaproteobacteria E branched-chain amino acid permease (azaleucine resistance) - - - - - - - - - - - - AzlC k141_577_1 1168065.DOK_07079 1.13e-75 238.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1J4Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_16585_1 926562.Oweho_3134 2.24e-56 198.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PBJJ@246874|Cryomorphaceae 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 k141_9570_1 1123368.AUIS01000011_gene1125 3.47e-25 105.0 COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU type II and III secretion system protein mshL - - ko:K12282 - - - - ko00000,ko02044 - - - STN,Secretin,Secretin_N_2 k141_9570_2 1198452.Jab_2c02780 3.97e-21 90.1 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VKIQ@28216|Betaproteobacteria,472K4@75682|Oxalobacteraceae 28216|Betaproteobacteria U AAA domain exeA2 - - ko:K02450,ko:K12283 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 k141_13849_1 1122207.MUS1_11745 2.03e-95 286.0 COG1158@1|root,COG1158@2|Bacteria,1PW77@1224|Proteobacteria,1RYAS@1236|Gammaproteobacteria,1XHRH@135619|Oceanospirillales 135619|Oceanospirillales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab k141_6126_1 1288826.MSNKSG1_07318 4.19e-200 574.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,464JA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DNA internalization-related competence protein ComEC Rec2 ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_16586_1 1500893.JQNB01000001_gene686 3.7e-66 209.0 COG1451@1|root,COG1451@2|Bacteria,1N6XC@1224|Proteobacteria,1SCR9@1236|Gammaproteobacteria,1X4I2@135614|Xanthomonadales 135614|Xanthomonadales S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 k141_12491_1 377629.TERTU_1662 3.27e-83 261.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,2PPX8@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE impJ2 - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k141_15153_2 1288826.MSNKSG1_12562 4.16e-124 359.0 COG0834@1|root,COG0834@2|Bacteria,1RI5R@1224|Proteobacteria,1S5PV@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_15153_3 1288826.MSNKSG1_12567 3.94e-176 496.0 COG3187@1|root,COG3650@1|root,COG3895@1|root,COG3187@2|Bacteria,COG3650@2|Bacteria,COG3895@2|Bacteria,1MXIV@1224|Proteobacteria,1S5KY@1236|Gammaproteobacteria,4698G@72275|Alteromonadaceae 1236|Gammaproteobacteria O META domain - - - - - - - - - - - - META,MliC k141_15153_4 1288826.MSNKSG1_12572 1.62e-201 559.0 COG2304@1|root,COG2304@2|Bacteria,1RIXD@1224|Proteobacteria,1S6EY@1236|Gammaproteobacteria,46B1D@72275|Alteromonadaceae 1236|Gammaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VPEP k141_15153_5 1288826.MSNKSG1_12577 0.0 1078.0 COG2936@1|root,COG2936@2|Bacteria,1QU2I@1224|Proteobacteria,1S1VW@1236|Gammaproteobacteria,469YI@72275|Alteromonadaceae 1236|Gammaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - - - - - - - - - - PepX_C,Peptidase_S15 k141_15153_6 1288826.MSNKSG1_12582 1.57e-182 507.0 COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,1S4N1@1236|Gammaproteobacteria,46AZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase gst - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_15153_7 1288826.MSNKSG1_12587 9.59e-246 673.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,1RQDX@1236|Gammaproteobacteria,46582@72275|Alteromonadaceae 1236|Gammaproteobacteria I Sterol desaturase - - - - - - - - - - - - FA_hydroxylase k141_11715_2 595460.RRSWK_02170 3.18e-113 335.0 COG1215@1|root,COG1215@2|Bacteria,2J0VI@203682|Planctomycetes 203682|Planctomycetes M Glycosyltransferase like family 2 - - - ko:K13002 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 k141_11715_3 1278309.KB907100_gene2087 3.91e-47 160.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XJ73@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_11079_1 396588.Tgr7_2879 7.66e-86 258.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1WX9I@135613|Chromatiales 135613|Chromatiales G Belongs to the ribulose-phosphate 3-epimerase family - - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_11079_2 1049564.TevJSym_ag00460 1.14e-120 349.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G HAD-hyrolase-like gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 HAD_2 k141_8318_2 1198232.CYCME_1610 8.47e-72 227.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,46026@72273|Thiotrichales 72273|Thiotrichales S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_19421_2 1515746.HR45_04915 1.15e-94 282.0 COG1280@1|root,COG1280@2|Bacteria,1R3YJ@1224|Proteobacteria,1RSMF@1236|Gammaproteobacteria,2QCMJ@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE k141_19421_3 1278309.KB907099_gene2570 4.49e-190 531.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XIPU@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_19421_4 1278309.KB907099_gene2571 1.6e-169 474.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XHEP@135619|Oceanospirillales 135619|Oceanospirillales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_3407_1 1122137.AQXF01000003_gene2254 3.66e-05 45.4 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_16608_1 396588.Tgr7_0321 4.09e-69 231.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_1321_1 1048983.EL17_14075 8.33e-68 218.0 COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,47KWG@768503|Cytophagia 976|Bacteroidetes EJ TIGRFAM L-asparaginases, type I ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_22204_1 2340.JV46_21510 2.34e-48 158.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1J5YH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S EVE domain - - - - - - - - - - - - EVE k141_1977_1 948565.AFFP02000003_gene1993 3.78e-124 361.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1Y72T@135625|Pasteurellales 135625|Pasteurellales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_11080_1 1123518.ARWI01000001_gene335 1.79e-51 180.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,4603V@72273|Thiotrichales 72273|Thiotrichales C Isocitrate dehydrogenase NADP-dependent, monomeric type - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_6776_1 1279019.ARQK01000020_gene2437 1.61e-82 255.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_7559_1 384676.PSEEN3906 3.33e-51 163.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria 1236|Gammaproteobacteria T YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05527,ko:K09780 - - - - ko00000,ko03000 - - - YCII k141_7559_2 1116472.MGMO_30c00080 1.83e-62 206.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1XDX1@135618|Methylococcales 135618|Methylococcales O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3 k141_5494_2 1115512.EH105704_03_00150 7.77e-53 180.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,3XPAR@561|Escherichia 1236|Gammaproteobacteria F DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_18725_1 926562.Oweho_1175 1.85e-67 218.0 2DB9N@1|root,2Z7XI@2|Bacteria,4NGR0@976|Bacteroidetes,1HYZR@117743|Flavobacteriia 976|Bacteroidetes S Glycosyl transferase family 90 lpsA - - - - - - - - - - - Glyco_transf_90 k141_18725_2 1101195.Meth11DRAFT_0216 1.14e-34 124.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KMXB@206350|Nitrosomonadales 206350|Nitrosomonadales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid - - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_18725_3 765910.MARPU_00855 1.47e-100 306.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P k141_14460_1 1288826.MSNKSG1_06118 2.06e-129 379.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,4642Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1271 Cytochrome bd-type quinol oxidase, subunit 1 cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I k141_14460_2 1288826.MSNKSG1_06113 1.28e-55 177.0 COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,1S1F0@1236|Gammaproteobacteria,467F2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_13183_2 323261.Noc_2665 1.48e-273 773.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales 135613|Chromatiales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_19422_1 314278.NB231_14803 1.67e-77 248.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_17302_1 1288826.MSNKSG1_04576 3.16e-63 203.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,46DFU@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1454 Alcohol dehydrogenase, class IV - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_17302_2 1288826.MSNKSG1_04571 5.89e-111 323.0 COG0834@1|root,COG0834@2|Bacteria,1NCKT@1224|Proteobacteria,1SD6E@1236|Gammaproteobacteria,46DIV@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_16609_1 990285.RGCCGE502_11861 1.87e-28 108.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,4BFDI@82115|Rhizobiaceae 28211|Alphaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 k141_11081_1 1123401.JHYQ01000007_gene514 1.39e-64 219.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,45ZVX@72273|Thiotrichales 72273|Thiotrichales C CoA binding domain - - - - - - - - - - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_18080_1 1192868.CAIU01000008_gene880 1.2e-158 468.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,43IB9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the GcvT family sardh - 1.5.3.19 ko:K19191 ko00760,ko01120,map00760,map01120 - R10102 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C k141_22205_2 1123503.KB908057_gene2698 2.84e-33 117.0 COG0640@1|root,COG0640@2|Bacteria,1ND8B@1224|Proteobacteria,2UI6G@28211|Alphaproteobacteria,2KGZ1@204458|Caulobacterales 204458|Caulobacterales K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 k141_22205_3 1232683.ADIMK_0447 2.28e-13 70.5 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RZYT@1236|Gammaproteobacteria,46AMJ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase family M48 - - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_8319_1 395493.BegalDRAFT_1677 5.95e-182 529.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent Clp protease ATP-binding subunit ClpA - - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_7560_1 641149.HMPREF9016_01713 3.88e-19 91.7 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,2KPGN@206351|Neisseriales 206351|Neisseriales C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_3409_1 1485544.JQKP01000002_gene1339 1.95e-27 110.0 2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,44VTJ@713636|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_21531_1 1439940.BAY1663_02017 1.69e-40 161.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB btuB GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - iECB_1328.ECB_03851,iECP_1309.ECP_4183,iSF_1195.SF4048,iS_1188.S3696 Plug,TonB_dep_Rec k141_9585_1 1216007.AOPM01000002_gene2610 1.82e-64 220.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,2Q0GF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_1322_1 640081.Dsui_1451 5.89e-43 152.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA k141_4003_1 1123368.AUIS01000001_gene2024 6.23e-139 416.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2NC0C@225057|Acidithiobacillales 225057|Acidithiobacillales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_4003_2 118005.AWNK01000001_gene2090 1.15e-35 125.0 COG3671@1|root,COG3671@2|Bacteria 2|Bacteria M membrane - - - - - - - - - - - - - k141_4003_3 572477.Alvin_2660 1.03e-26 107.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales 135613|Chromatiales S Methyltransferase - - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 k141_6777_1 5551.XP_003235001.1 1.2e-08 54.7 COG0106@1|root,KOG3055@2759|Eukaryota,39RKQ@33154|Opisthokonta,3NVJU@4751|Fungi,3QM1R@4890|Ascomycota,20EGY@147545|Eurotiomycetes,3B3U3@33183|Onygenales,3FYJ8@34384|Arthrodermataceae 4751|Fungi E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase HIS6 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_6777_2 1278309.KB907099_gene2501 1.01e-80 244.0 COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria,1XKCU@135619|Oceanospirillales 135619|Oceanospirillales E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 k141_2661_1 1278309.KB907108_gene1627 8.73e-147 422.0 COG0253@1|root,COG0253@2|Bacteria,1R68H@1224|Proteobacteria,1RYYA@1236|Gammaproteobacteria,1XNU5@135619|Oceanospirillales 135619|Oceanospirillales E Diaminopimelate epimerase - - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_2661_2 438753.AZC_1210 6.3e-27 123.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TXEZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 k141_2661_3 1278309.KB907108_gene1628 2.28e-149 434.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1RYH5@1236|Gammaproteobacteria,1XHN0@135619|Oceanospirillales 135619|Oceanospirillales P COG3639 ABC-type phosphate phosphonate transport system, permease component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - - k141_17303_1 768671.ThimaDRAFT_0841 3.65e-68 224.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C k141_19423_2 391615.ABSJ01000033_gene693 2.46e-19 85.5 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,1J75P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4 k141_12509_1 1121403.AUCV01000003_gene1792 9.19e-152 436.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,42P23@68525|delta/epsilon subdivisions,2WK75@28221|Deltaproteobacteria,2MIZ4@213118|Desulfobacterales 28221|Deltaproteobacteria P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k141_12509_2 626418.bglu_1g12280 1.02e-89 273.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2VIBF@28216|Betaproteobacteria,1K014@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component yejB - - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_14461_1 426114.THI_2042 2.02e-101 303.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator rbcR - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_13184_2 377629.TERTU_0636 4.32e-30 110.0 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,2PQE6@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S MazG-like family - - - - - - - - - - - - MazG-like k141_11716_1 1122212.AULO01000014_gene1219 2.42e-65 209.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_11716_3 349521.HCH_04640 2.3e-12 65.5 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1XRB8@135619|Oceanospirillales 135619|Oceanospirillales T helix_turn_helix, cAMP Regulatory protein - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_7561_1 1469613.JT55_15755 3.35e-115 342.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,3FCR1@34008|Rhodovulum 28211|Alphaproteobacteria F Adenylosuccinate lyase C-terminus purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k141_18081_1 553385.JEMF01000127_gene3542 3.17e-69 228.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XIWI@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_1978_1 391595.RLO149_c012620 1.02e-73 234.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,2P22X@2433|Roseobacter 28211|Alphaproteobacteria U Flp pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF k141_6778_1 1042375.AFPL01000007_gene2814 2.15e-101 304.0 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,464GA@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3385 FOG Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 k141_15961_1 1288826.MSNKSG1_01403 6.12e-234 664.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,464AD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the GPAT DAPAT family plsB GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - iECs_1301.ECs5024,iG2583_1286.G2583_4866 Acyltransferase k141_15961_2 1288826.MSNKSG1_01398 3.24e-184 513.0 COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,466ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanosine in position 1516 of 16S rRNA rsmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 ko:K15984 - - - - ko00000,ko01000,ko03009 - - - SAM_MT k141_15961_4 1288826.MSNKSG1_01388 1.08e-152 430.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,466QS@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k141_15961_5 1288826.MSNKSG1_01383 5.46e-150 422.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,46577@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 ADK,ADK_lid k141_15961_6 1288826.MSNKSG1_01378 0.0 884.0 COG1639@1|root,COG2606@1|root,COG1639@2|Bacteria,COG2606@2|Bacteria,1R46H@1224|Proteobacteria,1S1DF@1236|Gammaproteobacteria,46CHJ@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - - - - - - - - - - - HDOD,tRNA_edit k141_1324_1 384676.PSEEN4681 3.33e-50 171.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_4801_1 1278309.KB907107_gene1664 3.9e-15 72.4 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1XKBD@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_4801_2 1278309.KB907107_gene1665 8.09e-220 609.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1XIHC@135619|Oceanospirillales 135619|Oceanospirillales O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_13946_1 1121271.AUCM01000004_gene1212 2.53e-33 126.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall hydrolyses involved in spore germination sleB - - - - - - - - - - - Hydrolase_2 k141_3492_1 1124983.PFLCHA0_c54740 1.62e-39 141.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1YMC1@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 RibD_C,dCMP_cyt_deam_1 k141_3492_2 2340.JV46_06550 2.81e-24 96.7 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1J5U0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_13256_1 706587.Desti_5335 2.31e-29 120.0 COG3852@1|root,COG5000@1|root,COG3852@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42NE2@68525|delta/epsilon subdivisions 1224|Proteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K10909,ko:K14986 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513,M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE5,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,dCache_1 k141_13947_1 580332.Slit_2556 1.19e-55 192.0 COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,2W04K@28216|Betaproteobacteria 28216|Betaproteobacteria C V-type ATPase 116kDa subunit family - - - ko:K02123 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - V_ATPase_I k141_9067_2 768671.ThimaDRAFT_4686 1.17e-39 135.0 2E3G3@1|root,32YEY@2|Bacteria,1N87D@1224|Proteobacteria,1SDRX@1236|Gammaproteobacteria,1WZH7@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_2103_2 390235.PputW619_1517 6.97e-48 163.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1YWZP@136845|Pseudomonas putida group 1236|Gammaproteobacteria G Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_18126_1 225937.HP15_1348 1.74e-111 331.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RNIM@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP transporter tphA - - ko:K03762,ko:K12226 - - - - ko00000,ko02000,ko02044 2.A.1.6.4,3.A.7.9.1 - - MFS_1,Sugar_tr k141_21613_1 870187.Thini_1859 0.000113 44.3 2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,1S67B@1236|Gammaproteobacteria,462DF@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_21613_2 396595.TK90_0881 2.55e-34 132.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_13258_1 555778.Hneap_0600 1.18e-19 93.6 COG0784@1|root,COG2199@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales 135613|Chromatiales T PFAM EAL domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_3493_1 765914.ThisiDRAFT_0198 1.11e-72 237.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_9068_1 1288826.MSNKSG1_01883 1.21e-87 265.0 COG1262@1|root,COG1262@2|Bacteria,1PDSD@1224|Proteobacteria,1S4ZV@1236|Gammaproteobacteria,46CJV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase k141_18127_1 555778.Hneap_1337 8.04e-81 251.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales 135613|Chromatiales EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_1402_1 1278309.KB907099_gene2542 1.36e-258 721.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1XHGX@135619|Oceanospirillales 135619|Oceanospirillales V protein conserved in bacteria - - - ko:K09760 - - - - ko00000 - - - RmuC k141_1402_2 1278309.KB907099_gene2541 8.83e-52 165.0 2D9ER@1|root,32TT4@2|Bacteria,1N2HH@1224|Proteobacteria,1S97I@1236|Gammaproteobacteria,1XM5M@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_1402_3 1278309.KB907099_gene2539 5.26e-146 412.0 COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria,1XIIY@135619|Oceanospirillales 135619|Oceanospirillales S PFAM O-methyltransferase, family 3 - - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 k141_5582_1 768671.ThimaDRAFT_3562 1.71e-30 120.0 28JN1@1|root,33VHP@2|Bacteria,1NUCG@1224|Proteobacteria,1SNMY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5582_2 1049564.TevJSym_ah00790 6.16e-07 50.1 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1JAT3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D probably involved in intracellular septation ispZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K06190 - - - - ko00000 - - - IspA k141_14650_1 751994.AGIG01000028_gene1622 3.92e-31 118.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1J4XT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_14650_2 105559.Nwat_0553 5.61e-171 490.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales 135613|Chromatiales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_19529_1 640081.Dsui_1094 1.18e-35 126.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,2KWHZ@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k141_19529_2 105559.Nwat_0349 1.75e-193 562.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_6283_1 323261.Noc_1144 1.21e-157 449.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1WXAD@135613|Chromatiales 135613|Chromatiales J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_18828_1 1168067.JAGP01000001_gene1587 2.13e-71 223.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,463SP@72273|Thiotrichales 72273|Thiotrichales N Membrane MotB of proton-channel complex MotA/MotB - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_7680_1 479434.Sthe_1027 2.04e-26 110.0 COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi,27XWG@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_7680_2 550540.Fbal_0130 1.65e-78 236.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria 1236|Gammaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k141_11859_2 1049564.TevJSym_ak00590 7.39e-181 521.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1J5IS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_16739_1 247633.GP2143_11007 4.63e-60 202.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1J8NC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_16739_2 1278309.KB907107_gene1738 6.46e-44 147.0 COG1334@1|root,COG1334@2|Bacteria 2|Bacteria N flagellar protein FlaG flaG - - ko:K06603 - - - - ko00000,ko02035 - - - FlaG k141_16739_3 1123487.KB892836_gene3097 5.78e-26 114.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,2KUJB@206389|Rhodocyclales 206389|Rhodocyclales N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_4886_1 472759.Nhal_3150 9.92e-62 196.0 COG0569@1|root,COG0569@2|Bacteria,1RDDX@1224|Proteobacteria,1S3ZR@1236|Gammaproteobacteria,1WY9A@135613|Chromatiales 135613|Chromatiales C TrkA-N domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_4886_2 1232683.ADIMK_3166 1.73e-243 675.0 COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,1RMD7@1236|Gammaproteobacteria,469DH@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain pobA - 1.14.13.127,1.14.13.2 ko:K00481,ko:K05712 ko00360,ko00362,ko01100,ko01120,ko01220,map00360,map00362,map01100,map01120,map01220 M00545 R01298,R06786,R06787 RC00046,RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_4886_3 1278309.KB907099_gene2483 1.38e-149 428.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1XJFQ@135619|Oceanospirillales 135619|Oceanospirillales S TIGRFAM RarD protein rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA k141_4886_4 1278309.KB907099_gene2484 8.8e-185 520.0 COG3366@1|root,COG3366@2|Bacteria,1P2FE@1224|Proteobacteria,1RRXD@1236|Gammaproteobacteria,1XIY7@135619|Oceanospirillales 135619|Oceanospirillales S PFAM nucleoside recognition domain protein - - - - - - - - - - - - - k141_4886_5 1278309.KB907099_gene2485 7.68e-50 162.0 COG1522@1|root,COG1522@2|Bacteria,1RD38@1224|Proteobacteria,1S6Q6@1236|Gammaproteobacteria,1XKAS@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_20917_1 1288826.MSNKSG1_07673 1.14e-52 174.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,464W6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the bacterial glucokinase family glk GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iNRG857_1313.NRG857_12000 Glucokinase k141_20917_2 1288826.MSNKSG1_07678 0.0 1176.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,464QM@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family edd GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366 ILVD_EDD k141_20917_3 1288826.MSNKSG1_07683 0.0 893.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,463Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_20917_4 1288826.MSNKSG1_07688 3.61e-29 108.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,465M9@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase eda GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - iECOK1_1307.ECOK1_1968,iYL1228.KPN_02365 Aldolase k141_20218_1 1288826.MSNKSG1_05066 4.35e-23 92.4 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,466ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF924 k141_20218_2 1288826.MSNKSG1_05061 2.8e-77 231.0 COG2138@1|root,COG2138@2|Bacteria,1QCX8@1224|Proteobacteria,1SCUE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cobalamin (vitamin B12) biosynthesis CbiX - - 4.99.1.3 ko:K03795 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05807 RC01012 ko00000,ko00001,ko01000 - - - CbiX k141_20218_3 1288826.MSNKSG1_05056 8.07e-205 568.0 COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,465A2@72275|Alteromonadaceae 1236|Gammaproteobacteria S nucleoside-diphosphate sugar epimerase yfcH - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase k141_20218_4 1288826.MSNKSG1_07973 1.11e-200 556.0 COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,464QP@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0720 6-pyruvoyl-tetrahydropterin synthase SO2179 - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - PTPS k141_20218_5 1288826.MSNKSG1_07968 1.64e-78 238.0 COG2068@1|root,COG2068@2|Bacteria,1NG5Y@1224|Proteobacteria,1T1CY@1236|Gammaproteobacteria,467SH@72275|Alteromonadaceae 1236|Gammaproteobacteria S MobA-related protein - - - - - - - - - - - - NTP_transf_3 k141_20218_6 1288826.MSNKSG1_07963 9.87e-242 666.0 COG0784@1|root,COG0784@2|Bacteria,1N1YE@1224|Proteobacteria,1S9PD@1236|Gammaproteobacteria,468H1@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Response_reg k141_20218_7 1288826.MSNKSG1_07958 6.1e-17 84.7 COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,1SYQP@1236|Gammaproteobacteria,46BIB@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - MORN,PEGA k141_15347_1 626887.J057_02625 1.16e-302 865.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_15347_2 1122194.AUHU01000006_gene525 1.13e-135 385.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,1RR1E@1236|Gammaproteobacteria,464DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1989) ycgI - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_15347_3 1046714.AMRX01000001_gene1601 5.92e-122 353.0 COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,4641M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1989) IV02_09290 - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_15347_4 555778.Hneap_0795 2.99e-57 182.0 COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,1S85W@1236|Gammaproteobacteria,1X274@135613|Chromatiales 135613|Chromatiales K NikR C terminal nickel binding domain - - - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 k141_15347_5 314345.SPV1_06144 2.61e-134 392.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria 1224|Proteobacteria E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_6998_2 1415756.JQMY01000001_gene1246 8.86e-40 133.0 COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,2PEBW@252301|Oceanicola 28211|Alphaproteobacteria E Chorismate mutase type II tyrA - 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 k141_9777_1 1123399.AQVE01000003_gene2221 1.58e-77 249.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,460C3@72273|Thiotrichales 72273|Thiotrichales E PFAM Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_9777_2 472759.Nhal_0151 1.03e-22 96.3 COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,1T20G@1236|Gammaproteobacteria,1X0J7@135613|Chromatiales 135613|Chromatiales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_20935_1 1123054.KB907735_gene3312 1e-08 60.1 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1S04N@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GAF_2,GGDEF,PAS,PAS_3,PAS_4 k141_20935_2 1217718.ALOU01000011_gene804 1.16e-25 115.0 COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria,2VRTC@28216|Betaproteobacteria,1K6TE@119060|Burkholderiaceae 28216|Betaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,HAMP,PAS_4,dCache_1 k141_15360_1 1085623.GNIT_1864 1.49e-57 198.0 2DWHB@1|root,340BR@2|Bacteria,1QS8Y@1224|Proteobacteria,1SQBY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - OprB k141_15360_2 1122603.ATVI01000006_gene805 9.1e-58 199.0 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity shp - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C,DUF1924 k141_2113_1 398579.Spea_4196 4.91e-57 196.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAI3@267890|Shewanellaceae 1236|Gammaproteobacteria NT PFAM histidine kinase, HAMP region domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_3 k141_2113_2 313612.L8106_03989 4.28e-31 126.0 COG2199@1|root,COG2202@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales 1117|Cyanobacteria T GGDEF domain' - - - - - - - - - - - - CBS,GAF,GAF_2,GGDEF,PAS_3,PAS_8,PAS_9 k141_729_1 1116472.MGMO_105c00580 6.51e-154 450.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XER8@135618|Methylococcales 135618|Methylococcales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_8390_1 395493.BegalDRAFT_1618 2.35e-218 619.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,4608E@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_7696_2 472759.Nhal_3947 8.56e-145 415.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_7696_3 292415.Tbd_2797 3.91e-122 361.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1KS24@119069|Hydrogenophilales 119069|Hydrogenophilales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_13273_1 1082933.MEA186_15127 1.97e-79 244.0 COG0413@1|root,COG0413@2|Bacteria,1R9NX@1224|Proteobacteria,2U4E0@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Ketopantoate hydroxymethyltransferase - - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_11878_1 1031711.RSPO_c03251 3.18e-24 106.0 COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2VHDJ@28216|Betaproteobacteria,1KAIY@119060|Burkholderiaceae 28216|Betaproteobacteria S TIGRFAM outer membrane autotransporter barrel domain protein - - - - - - - - - - - - Autotransporter,He_PIG,TIG k141_10472_1 667121.ET1_10_00740 1.31e-05 47.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10472_2 1123401.JHYQ01000005_gene197 3.47e-73 234.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,45ZMS@72273|Thiotrichales 72273|Thiotrichales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_19547_1 1123060.JONP01000050_gene860 6.62e-21 92.8 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQ4H@204441|Rhodospirillales 204441|Rhodospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_7,PAS_9,dCache_1,dCache_2 k141_14668_1 930169.B5T_04011 1.81e-44 156.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales 135619|Oceanospirillales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_18847_4 1122599.AUGR01000014_gene634 7.85e-34 122.0 COG4341@1|root,COG4341@2|Bacteria,1N0MY@1224|Proteobacteria,1S8VV@1236|Gammaproteobacteria,1XM5Q@135619|Oceanospirillales 135619|Oceanospirillales S HD phosphohydrolase - - - - - - - - - - - - HD k141_20936_1 1449350.OCH239_01645 3.76e-78 246.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,4KK33@93682|Roseivivax 28211|Alphaproteobacteria O FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 k141_6999_2 1128398.Curi_c02480 6.41e-24 102.0 COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,26BMV@186813|unclassified Clostridiales 186801|Clostridia S N-methylation of lysine residues in flagellin K00599 fliB - - ko:K18475 - - - - ko00000,ko01000,ko02035 - - - CxxCxxCC k141_19_2 1042375.AFPL01000036_gene3047 5.02e-15 71.2 COG3011@1|root,COG3011@2|Bacteria,1PV30@1224|Proteobacteria,1SCCX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_11183_1 391595.RLO149_c019420 1.73e-73 225.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2TQZ1@28211|Alphaproteobacteria,2P2Q5@2433|Roseobacter 28211|Alphaproteobacteria S Tat (Twin-arginine translocation) pathway signal sequence domain protein - - - - - - - - - - - - Peptidase_M15_2 k141_3507_1 1123501.KB902279_gene530 2.17e-41 148.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2TU1V@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Guanine deaminase guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_13964_1 748247.AZKH_p0125 4.45e-106 314.0 COG1917@1|root,COG1917@2|Bacteria,1RH0Y@1224|Proteobacteria,2VWWA@28216|Betaproteobacteria 28216|Betaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_4901_1 500632.CLONEX_01661 5.27e-07 49.7 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia 186801|Clostridia J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_4901_2 866536.Belba_3280 4.17e-21 89.4 COG3339@1|root,COG3339@2|Bacteria,4NVFR@976|Bacteroidetes,47RD8@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 k141_7128_1 439235.Dalk_1995 9.57e-86 267.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X5IZ@28221|Deltaproteobacteria,2MPF3@213118|Desulfobacterales 28221|Deltaproteobacteria P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_14806_2 748658.KB907318_gene1011 9.25e-110 325.0 COG1116@1|root,COG1116@2|Bacteria,1R8N0@1224|Proteobacteria,1RYBX@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_21122_1 1538295.JY96_16275 2.19e-65 210.0 COG0845@1|root,COG0845@2|Bacteria,1R99C@1224|Proteobacteria,2VQDD@28216|Betaproteobacteria,1KM2A@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_9885_1 396588.Tgr7_0259 4.79e-99 314.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales 135613|Chromatiales O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_18982_1 1121022.ABENE_04570 9.67e-16 75.9 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2KFZC@204458|Caulobacterales 204458|Caulobacterales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_18982_2 1116472.MGMO_7c00140 1.25e-104 308.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XEBI@135618|Methylococcales 135618|Methylococcales S Belongs to the BI1 family - - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_12699_1 335283.Neut_2466 7.98e-91 294.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,373W6@32003|Nitrosomonadales 28216|Betaproteobacteria I Transmembrane secretion effector aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - Acyltransferase,MFS_1 k141_19673_1 1123355.JHYO01000017_gene3617 6.54e-58 205.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TWWT@28211|Alphaproteobacteria 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_19673_2 1165096.ARWF01000001_gene2209 5.62e-27 105.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,2KMHV@206350|Nitrosomonadales 206350|Nitrosomonadales S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 k141_2945_1 1237149.C900_05319 5.95e-14 75.9 2DM40@1|root,31MRJ@2|Bacteria,4NPHT@976|Bacteroidetes,47SI8@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 k141_2945_2 290512.Paes_0903 8.45e-09 55.5 COG0221@1|root,COG0221@2|Bacteria,1FE4R@1090|Chlorobi 1090|Chlorobi C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_12008_1 1288826.MSNKSG1_00251 2.15e-315 863.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4643Q@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DEADboxA,DbpA,Helicase_C k141_12008_2 1288826.MSNKSG1_00256 1.1e-106 308.0 COG1522@1|root,COG1522@2|Bacteria,1R7SW@1224|Proteobacteria,1S4QN@1236|Gammaproteobacteria,46CRF@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_12008_3 225937.HP15_859 0.0 1265.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_11360_1 1288826.MSNKSG1_00161 1.09e-156 447.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,464DY@72275|Alteromonadaceae 1236|Gammaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_11360_2 1288826.MSNKSG1_00166 3.32e-263 723.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46530@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_11360_3 1288826.MSNKSG1_00171 9.98e-215 593.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,46506@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECS88_1305.ECS88_0100 LpxC k141_11360_4 1288826.MSNKSG1_00176 1.05e-80 241.0 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SHDB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF721 k141_11360_5 1288826.MSNKSG1_00181 2.36e-216 598.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,465Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k141_11360_6 1288826.MSNKSG1_00186 1.39e-187 546.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_17590_1 443152.MDG893_04899 7.21e-80 264.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464CD@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mtrD_1 - - ko:K18138,ko:K18307 ko01501,ko01503,ko02024,map01501,map01503,map02024 M00644,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.20,2.A.6.2.32 - - ACR_tran k141_5027_1 1288826.MSNKSG1_09353 2e-266 740.0 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,466J7@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5027_2 1288826.MSNKSG1_09348 9.6e-245 672.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,4651S@72275|Alteromonadaceae 1236|Gammaproteobacteria C Lysine 2,3-aminomutase YodO family protein epmB GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Fer4_12,Fer4_14,Radical_SAM k141_5027_3 1288826.MSNKSG1_09343 8.52e-104 301.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,465T7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_16182_1 1288826.MSNKSG1_06838 9.41e-103 311.0 COG1541@1|root,COG1541@2|Bacteria,1RFV4@1224|Proteobacteria,1S519@1236|Gammaproteobacteria 1236|Gammaproteobacteria H COG1541 Coenzyme F390 synthetase - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding k141_3670_1 305900.GV64_13910 4.25e-28 117.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,1XI4W@135619|Oceanospirillales 135619|Oceanospirillales E 4-hydroxyphenylpyruvate dioxygenase - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 k141_3670_2 1122201.AUAZ01000014_gene263 3.82e-44 158.0 COG1082@1|root,COG1082@2|Bacteria,1PA26@1224|Proteobacteria,1S10U@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Xylose isomerase - - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AP_endonuc_2 k141_21757_1 768671.ThimaDRAFT_2230 2.08e-22 97.4 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1WXE4@135613|Chromatiales 135613|Chromatiales J Allophanate hydrolase - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_21757_2 225937.HP15_3159 7.44e-163 458.0 COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,1RN60@1236|Gammaproteobacteria,4647Y@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component cysA_3 - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_21757_3 1318628.MARLIPOL_04745 7.75e-170 477.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RS50@1236|Gammaproteobacteria,464VG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component tauC - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_21757_4 225937.HP15_3157 1.25e-197 553.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,46ABG@72275|Alteromonadaceae 1236|Gammaproteobacteria E alpha/beta hydrolase fold - - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_21757_5 1479237.JMLY01000001_gene3665 7.16e-136 395.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RR0P@1236|Gammaproteobacteria,464S1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain glnT - 6.3.1.11,6.3.1.2 ko:K01915,ko:K09470 ko00220,ko00250,ko00330,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00330,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 M00136 R00253,R07414 RC00010,RC00090,RC00096,RC02798 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Gln-synt_C k141_3671_1 870187.Thini_2104 1.94e-33 130.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,460ES@72273|Thiotrichales 72273|Thiotrichales MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_21758_1 1121904.ARBP01000005_gene4672 9.56e-10 59.7 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_21758_2 1336803.PHEL49_1881 3.37e-33 127.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1I0HE@117743|Flavobacteriia,3VX6W@52959|Polaribacter 976|Bacteroidetes J Elongation factor G, domain IV fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_5029_1 765914.ThisiDRAFT_0143 6.7e-47 169.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WXEW@135613|Chromatiales 135613|Chromatiales T Signal transducing histidine kinase, homodimeric - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_12018_1 999141.GME_09626 3.38e-17 82.8 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XHE2@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_12018_2 472759.Nhal_2797 2.48e-24 94.4 COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales 135613|Chromatiales H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k141_16184_1 617140.AJZE01000069_gene4142 2.02e-29 124.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales 135623|Vibrionales L COG1643 HrpA-like helicases hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_8537_2 555778.Hneap_1393 2.31e-14 73.9 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1WWHB@135613|Chromatiales 135613|Chromatiales E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_2242_1 765910.MARPU_01120 1.58e-28 109.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1WYH1@135613|Chromatiales 135613|Chromatiales S PFAM FxsA cytoplasmic membrane protein - - - ko:K07113 - - - - ko00000 - - - FxsA k141_2967_1 1112216.JH594425_gene1758 3.55e-64 244.0 COG3485@1|root,COG3485@2|Bacteria,1QUNE@1224|Proteobacteria,2U26Y@28211|Alphaproteobacteria,2K38K@204457|Sphingomonadales 204457|Sphingomonadales Q Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 k141_5778_1 1278309.KB907099_gene2641 4.16e-220 667.0 COG0515@1|root,COG0642@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1T55X@1236|Gammaproteobacteria,1XI8Z@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg k141_11361_1 983544.Lacal_2776 3.15e-05 47.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HWXA@117743|Flavobacteriia 976|Bacteroidetes E amino acid carrier protein - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_11361_2 1121937.AUHJ01000006_gene2416 2.06e-44 149.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,4674J@72275|Alteromonadaceae 1236|Gammaproteobacteria S aspartyl protease orf - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_17591_1 857087.Metme_0461 2.43e-56 184.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XDZI@135618|Methylococcales 135618|Methylococcales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_17591_2 1195246.AGRI_09230 1.19e-45 155.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE k141_4362_1 269799.Gmet_1128 1.6e-81 266.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria,43T9S@69541|Desulfuromonadales 28221|Deltaproteobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k141_13431_1 1168067.JAGP01000001_gene1149 2.47e-81 242.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_13431_2 90813.JQMT01000001_gene886 3.78e-36 125.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,460RC@72273|Thiotrichales 72273|Thiotrichales O FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_153_1 1305735.JAFT01000005_gene1604 2.04e-42 145.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,2UF72@28211|Alphaproteobacteria,2PEF5@252301|Oceanicola 28211|Alphaproteobacteria S FxsA cytoplasmic membrane protein fxsA - - ko:K07113 - - - - ko00000 - - - FxsA k141_10647_1 1124780.ANNU01000028_gene991 3.07e-120 350.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family crt - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 k141_21142_1 189753.AXAS01000062_gene8434 9.14e-40 150.0 COG1289@1|root,COG1289@2|Bacteria,1Q5JG@1224|Proteobacteria,2VBX6@28211|Alphaproteobacteria,3K2KA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Aromatic acid exporter family member 1 - - - - - - - - - - - - FUSC k141_3672_1 1121035.AUCH01000045_gene3247 7.42e-38 134.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2VRAI@28216|Betaproteobacteria,2KW74@206389|Rhodocyclales 206389|Rhodocyclales NT Chemotaxis signal transduction protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_3672_2 1123274.KB899415_gene2438 2.82e-05 46.2 COG2201@1|root,COG2201@2|Bacteria,2J6I0@203691|Spirochaetes 203691|Spirochaetes NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB-2 - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_7142_2 391625.PPSIR1_33309 8.87e-07 50.4 COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria 1224|Proteobacteria KT transcription factor binding - - - - - - - - - - - - - k141_20408_2 655812.HMPREF0061_0445 6.31e-35 132.0 COG1216@1|root,COG1216@2|Bacteria,1V3IY@1239|Firmicutes,4ISXW@91061|Bacilli 91061|Bacilli S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_20408_3 583345.Mmol_1036 1.41e-70 228.0 COG1216@1|root,COG1216@2|Bacteria,1R132@1224|Proteobacteria,2VT3B@28216|Betaproteobacteria,2KNDT@206350|Nitrosomonadales 206350|Nitrosomonadales S Glycosyltransferase like family 2 - - - ko:K12991 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 k141_15543_2 391613.RTM1035_02065 2.42e-25 100.0 COG2246@1|root,COG2246@2|Bacteria,1N6ST@1224|Proteobacteria,2UCW9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM GtrA family protein - - - - - - - - - - - - GtrA k141_1565_1 1121896.JMLU01000045_gene1464 6.39e-32 120.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia,2NV4Z@237|Flavobacterium 976|Bacteroidetes K AraC family transcriptional - - - - - - - - - - - - HTH_18 k141_1565_2 225117.XP_009356603.1 2.07e-72 231.0 COG0491@1|root,KOG0814@2759|Eukaryota,37MVP@33090|Viridiplantae,3GDGT@35493|Streptophyta,4JDAM@91835|fabids 35493|Streptophyta S Persulfide dioxygenase ETHE1 homolog - - 1.13.11.18 ko:K17725 ko00920,map00920 - R08678 RC02313 ko00000,ko00001,ko01000,ko03029 - - - Lactamase_B k141_1565_3 216432.CA2559_06440 5.57e-06 48.1 COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia 976|Bacteroidetes P rhodanese-related sulfurtransferase - - - - - - - - - - - - Rhodanese,Thioredoxin k141_2243_1 1265503.KB905161_gene3193 1.51e-63 208.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,2Q5V3@267889|Colwelliaceae 1236|Gammaproteobacteria E Aromatic amino acid lyase hutH GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic k141_2243_2 1535422.ND16A_2815 1.67e-18 84.3 COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria,2Q5WF@267889|Colwelliaceae 1236|Gammaproteobacteria E Urocanase C-terminal domain hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_9201_1 1158165.KB898874_gene1911 3.48e-53 183.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXMA@135613|Chromatiales 135613|Chromatiales T Chemotaxis sensory transducer - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_2968_1 411154.GFO_0851 3.13e-98 302.0 COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,1HZX1@117743|Flavobacteriia 976|Bacteroidetes E peptidase M24 - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_16897_1 1278309.KB907102_gene275 8.19e-287 797.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XIWM@135619|Oceanospirillales 135619|Oceanospirillales L DNA helicase recQ1 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_16897_2 1278309.KB907102_gene274 2.79e-122 350.0 COG3318@1|root,COG3318@2|Bacteria,1NA8N@1224|Proteobacteria,1S4CW@1236|Gammaproteobacteria,1XS72@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family (UPF0149) - - - ko:K07039 - - - - ko00000 - - - UPF0149 k141_16897_3 1278309.KB907102_gene273 1.2e-67 209.0 COG3133@1|root,COG3133@2|Bacteria,1RA1D@1224|Proteobacteria,1S202@1236|Gammaproteobacteria,1XKSA@135619|Oceanospirillales 135619|Oceanospirillales M Glycine zipper 2TM domain - - - ko:K06077 - - - - ko00000 - - - Rick_17kDa_Anti k141_16897_4 1122201.AUAZ01000036_gene1218 3.95e-129 382.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RP0T@1236|Gammaproteobacteria,46CQ0@72275|Alteromonadaceae 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc_2 k141_16897_5 857087.Metme_2447 8.22e-16 76.3 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,1XEI6@135618|Methylococcales 135618|Methylococcales V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_14835_1 877455.Metbo_1193 5.6e-24 98.2 COG0500@1|root,arCOG01783@2157|Archaea,2XV4B@28890|Euryarchaeota 28890|Euryarchaeota Q Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_14835_2 870187.Thini_3645 4.8e-131 384.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,4601D@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_12019_1 1198232.CYCME_1044 1.72e-150 440.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,461YX@72273|Thiotrichales 72273|Thiotrichales C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_7853_1 1288826.MSNKSG1_16631 2.13e-167 470.0 COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,1S1M7@1236|Gammaproteobacteria,468DW@72275|Alteromonadaceae 1236|Gammaproteobacteria K Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,GerE k141_7853_2 1517681.HW45_05280 2.74e-19 96.7 COG2771@1|root,COG2771@2|Bacteria,1PDSX@1224|Proteobacteria,1TBHP@1236|Gammaproteobacteria,1XXYQ@135623|Vibrionales 135623|Vibrionales K COG2771 DNA-binding HTH domain-containing proteins - - - - - - - - - - - - GerE k141_6522_1 1173029.JH980292_gene2126 1.77e-25 107.0 COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales 1117|Cyanobacteria T COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3 k141_6522_2 1123393.KB891333_gene2612 2.3e-84 250.0 COG0607@1|root,COG0607@2|Bacteria,1RKAQ@1224|Proteobacteria,2VWGP@28216|Betaproteobacteria,1KSAS@119069|Hydrogenophilales 119069|Hydrogenophilales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_14931_1 1123401.JHYQ01000007_gene566 1.69e-36 135.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,46079@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_14931_2 566466.NOR53_189 4.04e-09 58.5 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1SCSV@1236|Gammaproteobacteria,1JA6Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S MobA-like NTP transferase domain ygfJ - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k141_5154_1 1415780.JPOG01000001_gene3066 1.91e-11 63.9 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1X57R@135614|Xanthomonadales 135614|Xanthomonadales S Predicted integral membrane protein (DUF2189) - - - - - - - - - - - - DUF2189 k141_5154_2 1202962.KB907153_gene610 1.75e-25 103.0 COG3091@1|root,COG3091@2|Bacteria,1RJW4@1224|Proteobacteria,1S70F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the SprT family sprT - - ko:K02742 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT k141_19149_1 2340.JV46_08600 2.3e-36 129.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1J5WR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_989_1 1026882.MAMP_02431 1.64e-83 263.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462DX@72273|Thiotrichales 72273|Thiotrichales M PFAM Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_989_2 1144275.COCOR_00225 1.24e-40 145.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42UHA@68525|delta/epsilon subdivisions,2WQA0@28221|Deltaproteobacteria,2YUHZ@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_19791_1 1116472.MGMO_37c00130 7.15e-46 157.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1T08M@1236|Gammaproteobacteria,1XG8Q@135618|Methylococcales 135618|Methylococcales Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH k141_3112_1 1173024.KI912152_gene508 1.85e-27 105.0 COG3316@1|root,COG3316@2|Bacteria,1G3EB@1117|Cyanobacteria 1117|Cyanobacteria L COG3316 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_IS240 k141_8644_1 93220.LV28_11260 5.56e-48 160.0 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria,1K734@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - DUF1269 k141_12854_1 1122599.AUGR01000006_gene3699 2.85e-30 117.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1XHW4@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_12854_2 1278309.KB907101_gene644 1.89e-287 790.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1XHYX@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA - 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_12854_3 207954.MED92_09321 1.98e-277 760.0 COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,1XHY2@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB - 1.6.5.8 ko:K00347 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE k141_12854_4 1278309.KB907101_gene646 1.29e-152 432.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1XH23@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind k141_12854_5 1278309.KB907101_gene647 4.73e-136 387.0 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,1XHE7@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD - 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_12854_7 1278309.KB907101_gene649 1.53e-286 783.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XI4A@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF - 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_12854_8 1278309.KB907101_gene650 1.19e-170 485.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XHN2@135619|Oceanospirillales 135619|Oceanospirillales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_12854_9 207954.MED92_09351 2.4e-21 86.3 COG2991@1|root,COG2991@2|Bacteria,1NI0R@1224|Proteobacteria,1SGJF@1236|Gammaproteobacteria,1XM95@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K05952 - - - - ko00000 - - - NqrM k141_291_1 1278309.KB907106_gene1287 2.74e-117 338.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XJPQ@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig k141_291_2 1278309.KB907106_gene1286 2.62e-16 70.9 2EKWS@1|root,33EKA@2|Bacteria,1NP87@1224|Proteobacteria,1SGWH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_291_3 1278309.KB907106_gene1285 5.01e-158 450.0 COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RY7R@1236|Gammaproteobacteria,1XRNQ@135619|Oceanospirillales 135619|Oceanospirillales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_16289_1 444158.MmarC6_1729 0.000825 41.2 COG2201@1|root,arCOG02382@2157|Archaea,2XUKR@28890|Euryarchaeota,23Q4X@183939|Methanococci 183939|Methanococci N catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_16289_2 1286106.MPL1_06129 7.75e-78 239.0 COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,4624C@72273|Thiotrichales 72273|Thiotrichales NT Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k141_16289_3 765914.ThisiDRAFT_0314 1.96e-104 312.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1WXKT@135613|Chromatiales 135613|Chromatiales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_16289_4 1158182.KB905024_gene9 3.58e-74 251.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXKY@135613|Chromatiales 135613|Chromatiales T PFAM chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,NIT,PAS_3,PAS_8,PAS_9 k141_17746_1 1089551.KE386572_gene4622 5.46e-38 136.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TR5A@28211|Alphaproteobacteria,4BQ5C@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria N MotA/TolQ/ExbB proton channel family motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_9324_1 944435.AXAJ01000002_gene4512 1.04e-83 263.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,1K1XI@119060|Burkholderiaceae 28216|Betaproteobacteria O XdhC and CoxI family pucA - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_9324_2 748247.AZKH_3902 1.42e-35 135.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,2KVA6@206389|Rhodocyclales 206389|Rhodocyclales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_14233_1 1288826.MSNKSG1_11398 8.66e-158 443.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,464HP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG4221 Short-chain alcohol dehydrogenase of - - - - - - - - - - - - adh_short k141_17000_1 1288826.MSNKSG1_13922 5.47e-168 480.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,465CT@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport ethA GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 1.14.13.22 ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 - R02231,R06622 RC00662,RC01550 ko00000,ko00001,ko01000 - - - FMO-like,NAD_binding_8,Pyr_redox_3 k141_17000_2 1288826.MSNKSG1_13917 1.13e-275 758.0 COG4590@1|root,COG4590@2|Bacteria,1QY99@1224|Proteobacteria,1SMTM@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - - k141_17000_3 1288826.MSNKSG1_13912 5.12e-274 754.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,464WF@72275|Alteromonadaceae 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_17000_4 1288826.MSNKSG1_13907 6.25e-91 268.0 COG1266@1|root,COG1266@2|Bacteria,1ND7U@1224|Proteobacteria 1224|Proteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_17000_5 225937.HP15_3605 9.51e-306 850.0 COG2133@1|root,COG2133@2|Bacteria,1R65J@1224|Proteobacteria,1RYQV@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Large extracellular alpha-helical protein - - - - - - - - - - - - - k141_17000_6 1288826.MSNKSG1_13902 2.28e-150 425.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,467CK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein W ompW - - ko:K07275 - - - - ko00000 - - - OmpW k141_17000_7 1288826.MSNKSG1_13897 3.72e-108 311.0 COG1733@1|root,COG1733@2|Bacteria,1RIZT@1224|Proteobacteria,1S5HB@1236|Gammaproteobacteria,467RM@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulators - - - - - - - - - - - - HxlR k141_17000_8 1288826.MSNKSG1_13892 6.88e-137 394.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,464MK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_20563_1 314271.RB2654_07336 3.59e-25 99.8 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2U1Y3@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_20563_2 391626.OAN307_c34960 3.14e-97 293.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Xaa-Pro aminopeptidase - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k141_6523_1 1385515.N791_12070 1.85e-127 378.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1X482@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N k141_2367_1 1331060.RLDS_01595 8.52e-60 204.0 COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,2K2T8@204457|Sphingomonadales 204457|Sphingomonadales L Transposase IS116/IS110/IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_10777_1 243233.MCA2966 1.46e-68 217.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales 135618|Methylococcales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N k141_10777_2 498211.CJA_2421 2.05e-112 341.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1FG97@10|Cellvibrio 1236|Gammaproteobacteria C FAD dependent oxidoreductase eryB - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO k141_10777_4 1123392.AQWL01000007_gene984 1.98e-231 647.0 COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,2VJFD@28216|Betaproteobacteria,1KRCB@119069|Hydrogenophilales 119069|Hydrogenophilales P FAD-binding domain - - - - - - - - - - - - FAD_binding_8,Ferric_reduct k141_10777_5 324057.Pjdr2_0380 2.32e-18 87.4 COG2199@1|root,COG2199@2|Bacteria,1TR65@1239|Firmicutes,4HBA6@91061|Bacilli,26RG7@186822|Paenibacillaceae 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 k141_11457_1 1288826.MSNKSG1_06973 6.54e-233 647.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,464MI@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2148 Sugar transferases involved in lipopolysaccharide synthesis lthA - - - - - - - - - - - Bac_transf,CoA_binding_3 k141_11457_2 1288826.MSNKSG1_06968 2.59e-125 358.0 COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,1S35N@1236|Gammaproteobacteria,464WW@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export wza - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_11457_3 1288826.MSNKSG1_06963 9.06e-198 562.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,465VX@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - GNVR,Wzz k141_7274_1 314345.SPV1_02317 7.19e-277 778.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria 1224|Proteobacteria T GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_7274_2 1122599.AUGR01000004_gene2140 1.98e-142 408.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XKAP@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_7274_3 717774.Marme_3918 3.85e-37 140.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1XN54@135619|Oceanospirillales 135619|Oceanospirillales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_14932_1 32264.tetur01g16401.1 6.07e-10 65.1 COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa,3D40D@33213|Bilateria,4208T@6656|Arthropoda 33208|Metazoa L Integrase core domain - - - - - - - - - - - - Chromo,rve k141_3785_1 1122134.KB893650_gene237 1.18e-52 173.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1XJAQ@135619|Oceanospirillales 135619|Oceanospirillales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_3785_2 379731.PST_0054 1.44e-35 137.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNF@1236|Gammaproteobacteria,1Z0ZR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9 k141_19792_1 999549.KI421513_gene3408 1.12e-39 145.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,280JK@191028|Leisingera 28211|Alphaproteobacteria C Domain of unknown function (DUF4445) nqrF - - - - - - - - - - - DUF4445,Fer2 k141_8018_1 1123400.KB904747_gene552 3.04e-60 202.0 COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,1RQCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Radical SAM - - - - - - - - - - - - B12-binding,DUF4080,Radical_SAM k141_1712_1 1278309.KB907105_gene1494 1.81e-83 247.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1XKJ1@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III subunit chi - - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k141_1712_2 1278309.KB907105_gene1495 1.45e-172 492.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XH34@135619|Oceanospirillales 135619|Oceanospirillales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_990_1 713586.KB900536_gene32 3.12e-59 189.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1WYNA@135613|Chromatiales 135613|Chromatiales S Belongs to the CinA family - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_10789_2 1122201.AUAZ01000020_gene2739 5.93e-148 427.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465UK@72275|Alteromonadaceae 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_10789_3 1278309.KB907099_gene2797 1.43e-133 380.0 COG1396@1|root,COG1396@2|Bacteria,1R6PS@1224|Proteobacteria,1T24B@1236|Gammaproteobacteria,1XRRZ@135619|Oceanospirillales 135619|Oceanospirillales K Helix-turn-helix domain - - - - - - - - - - - - Cupin_2,HTH_3 k141_10789_4 1278309.KB907099_gene2798 6.09e-274 757.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XIF9@135619|Oceanospirillales 135619|Oceanospirillales E Serine dehydratase - - - - - - - - - - - - SDH_alpha,SDH_beta k141_10789_5 1278309.KB907099_gene2799 1.52e-66 214.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XH2G@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_15647_1 765912.Thimo_0822 8.83e-33 127.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_15647_2 765912.Thimo_0821 2.91e-20 88.6 COG0790@1|root,COG0790@2|Bacteria,1QCXZ@1224|Proteobacteria,1TKB7@1236|Gammaproteobacteria,1X1ES@135613|Chromatiales 135613|Chromatiales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_14935_1 1288826.MSNKSG1_06808 8.81e-212 585.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_14935_2 1288826.MSNKSG1_06813 0.0 1312.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,4643T@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase prsK - - - - - - - - - - - GAF_2,HATPase_c k141_14935_3 1288826.MSNKSG1_06818 3.28e-304 832.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4650W@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains prsR - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_14935_4 1288826.MSNKSG1_06823 0.0 1401.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,4675F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_14,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8 k141_12875_1 265072.Mfla_2541 2.31e-141 421.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,2KKSN@206350|Nitrosomonadales 206350|Nitrosomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_8660_1 1278309.KB907102_gene185 3.66e-137 409.0 COG4191@1|root,COG4191@2|Bacteria,1R4YU@1224|Proteobacteria,1RSG2@1236|Gammaproteobacteria,1XI49@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 k141_10030_1 1278309.KB907100_gene1806 5.77e-132 387.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XJH7@135619|Oceanospirillales 135619|Oceanospirillales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_10030_2 1278309.KB907100_gene1805 0.0 1027.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1XI53@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_20579_1 717785.HYPMC_1738 4.61e-43 159.0 COG0457@1|root,COG1413@1|root,COG3303@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,COG3303@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3N875@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 k141_312_1 1280950.HJO_07927 1.64e-58 187.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HxlR,SCP2 k141_19806_1 1278309.KB907103_gene1086 4.94e-71 222.0 COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1XJ5V@135619|Oceanospirillales 135619|Oceanospirillales L COG0084 Mg-dependent DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_2386_1 1198232.CYCME_0364 1.17e-248 699.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,45ZT8@72273|Thiotrichales 72273|Thiotrichales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_10790_2 1345695.CLSA_c39970 7.26e-16 79.7 COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,248JA@186801|Clostridia,36EW1@31979|Clostridiaceae 186801|Clostridia M glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3 k141_14936_1 28229.ND2E_1445 1.43e-49 179.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,2Q5NQ@267889|Colwelliaceae 1236|Gammaproteobacteria KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_10031_1 95619.PM1_0216130 4.45e-58 191.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 k141_16304_1 697282.Mettu_1061 1.82e-156 482.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_12168_1 1278309.KB907100_gene2212 2.41e-95 293.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XIYC@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_12168_2 1278309.KB907100_gene2211 4.92e-241 667.0 COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,1RMHC@1236|Gammaproteobacteria,1XNR8@135619|Oceanospirillales 135619|Oceanospirillales EGP Uncharacterised MFS-type transporter YbfB - - - - - - - - - - - - MFS_4 k141_4630_2 391626.OAN307_c07600 5.72e-37 134.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - NTP_transf_3,XdhC_C,XdhC_CoxI k141_5307_1 754476.Q7A_610 4.41e-49 166.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales 72273|Thiotrichales I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_5307_2 754476.Q7A_610 5.87e-71 224.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales 72273|Thiotrichales I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_17876_1 160492.XF_1260 8.62e-31 117.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1X41E@135614|Xanthomonadales 135614|Xanthomonadales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_17876_2 472759.Nhal_2092 5.68e-142 420.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1WW6M@135613|Chromatiales 135613|Chromatiales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_9425_1 1237149.C900_01376 1.89e-51 181.0 COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 k141_19908_1 388401.RB2150_05418 4.33e-89 273.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,3ZGI6@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_17124_1 1298593.TOL_0348 2.29e-19 93.6 COG0582@1|root,COG0582@2|Bacteria,1RAN4@1224|Proteobacteria,1S5SI@1236|Gammaproteobacteria,1XPF9@135619|Oceanospirillales 135619|Oceanospirillales L Phage integrase family - - - - - - - - - - - - Phage_integrase k141_441_1 1200792.AKYF01000006_gene1440 1.64e-93 298.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae 91061|Bacilli T Diguanylate cyclase - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MHYT,PAS,PAS_4,PAS_9 k141_18518_1 580332.Slit_0285 6.95e-14 67.8 COG0607@1|root,COG0607@2|Bacteria,1PGBP@1224|Proteobacteria,2WAFE@28216|Betaproteobacteria,44WMW@713636|Nitrosomonadales 28216|Betaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_18518_2 1121861.KB899910_gene905 9.19e-130 380.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2JPZ6@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase family 2 - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 k141_15789_1 28072.Nos7524_1698 4.37e-103 328.0 COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1HJKB@1161|Nostocales 1117|Cyanobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_21364_1 78245.Xaut_2614 4.16e-109 321.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U2DD@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_7388_1 95619.PM1_0202125 2.08e-84 259.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RSKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM Epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 k141_5969_1 95619.PM1_0208865 1.43e-175 499.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria 1236|Gammaproteobacteria E belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_3246_1 1121403.AUCV01000035_gene3791 4.6e-133 391.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2WKSV@28221|Deltaproteobacteria,2MHUQ@213118|Desulfobacterales 28221|Deltaproteobacteria P Na H antiporter - - - - - - - - - - - - CitMHS,PAS k141_5329_2 1278309.KB907111_gene3396 4.07e-97 298.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1XHX6@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_19305_1 1278309.KB907101_gene627 1.51e-148 432.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XI2V@135619|Oceanospirillales 135619|Oceanospirillales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_10928_1 313598.MED152_05425 9.63e-05 49.3 COG0204@1|root,COG0560@1|root,COG2937@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,COG2937@2|Bacteria,4NW8D@976|Bacteroidetes,1I6XY@117743|Flavobacteriia,3VV8T@52959|Polaribacter 976|Bacteroidetes EI haloacid dehalogenase-like hydrolase - - 2.3.1.51,3.1.3.3 ko:K00655,ko:K15781 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase,HAD k141_11581_1 371731.Rsw2DRAFT_0571 1.12e-14 74.3 COG3853@1|root,COG3853@2|Bacteria,1MZ3B@1224|Proteobacteria,2TQZD@28211|Alphaproteobacteria,1FAQ2@1060|Rhodobacter 28211|Alphaproteobacteria P Belongs to the TelA family telA - - - - - - - - - - - TelA k141_11581_2 571166.KI421509_gene383 4.88e-165 470.0 COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2TRUP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S virion core protein (lumpy skin disease virus) ydjI - - - - - - - - - - - Band_7_1,DUF4339,SHOCT k141_12326_1 314345.SPV1_12812 9.45e-108 332.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria 1224|Proteobacteria P Von willebrand factor, type a cbbO - - - - - - - - - - - VWA k141_12326_2 1163617.SCD_n02850 1.82e-69 223.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria 28216|Betaproteobacteria H RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site cbbM - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_17893_1 1328313.DS2_02123 1.18e-58 188.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,466RY@72275|Alteromonadaceae 1236|Gammaproteobacteria S VIT family - - - - - - - - - - - - VIT1 k141_21385_1 977880.RALTA_A0234 2.69e-45 162.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,1KCEV@119060|Burkholderiaceae 28216|Betaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain creC - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,dCache_3 k141_22048_1 1237149.C900_04468 6.08e-165 479.0 COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,47KVG@768503|Cytophagia 976|Bacteroidetes M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_4643_1 715451.ambt_16210 9.74e-25 101.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1T075@1236|Gammaproteobacteria,4677C@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_5330_1 95619.PM1_0205980 4.31e-19 86.7 COG0223@1|root,COG0451@1|root,COG0223@2|Bacteria,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria GJM Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011 ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R02984,R07658,R07660 RC00026,RC00289,RC01575,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 - - iPC815.YPO2420,iSFV_1184.SFV_2325 Epimerase,Formyl_trans_C,Formyl_trans_N k141_5330_2 425104.Ssed_0923 1.82e-62 201.0 COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,1RQ0R@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnD GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - ko:K13014 ko00520,ko01503,map00520,map01503 M00721,M00761 R07662 RC00323,RC01575 ko00000,ko00001,ko00002,ko01000,ko01005 - - iB21_1397.B21_02141,iBWG_1329.BWG_2029,iEC042_1314.EC042_2499,iECBD_1354.ECBD_1403,iECB_1328.ECB_02182,iECDH10B_1368.ECDH10B_2416,iECDH1ME8569_1439.ECDH1ME8569_2192,iECD_1391.ECD_02182,iECO103_1326.ECO103_2722,iECO111_1330.ECO111_3006,iECO26_1355.ECO26_3246,iECUMN_1333.ECUMN_2597,iECW_1372.ECW_m2447,iEKO11_1354.EKO11_1508,iETEC_1333.ETEC_2390,iEcDH1_1363.EcDH1_1402,iEcHS_1320.EcHS_A2401,iEcolC_1368.EcolC_1393,iJO1366.b2256,iSFV_1184.SFV_2326,iSSON_1240.SSON_2317,iUMNK88_1353.UMNK88_2808,iWFL_1372.ECW_m2447,iY75_1357.Y75_RS11830 Polysacc_deac_1 k141_12327_1 1286171.EAL2_c07760 2.47e-54 178.0 COG0683@1|root,COG2335@1|root,COG0683@2|Bacteria,COG2335@2|Bacteria,1VDJ1@1239|Firmicutes,24DID@186801|Clostridia 186801|Clostridia M Beta-Ig-H3 fasciclin - - - - - - - - - - - - Cu_amine_oxidN1,Fasciclin k141_17142_1 472759.Nhal_0785 2.04e-33 121.0 COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,1S17V@1236|Gammaproteobacteria,1WWE8@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane - - - ko:K02120 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_D k141_13702_2 443152.MDG893_18372 1.76e-112 336.0 28MV3@1|root,2ZB2R@2|Bacteria,1N53J@1224|Proteobacteria,1SBDN@1236|Gammaproteobacteria,467N4@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF560 k141_13702_4 1288826.MSNKSG1_14047 5.98e-63 208.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,465MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_11582_1 472759.Nhal_3071 4.68e-95 299.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1WWWM@135613|Chromatiales 135613|Chromatiales O PFAM peptidase M48 Ste24p - - - - - - - - - - - - Peptidase_M48 k141_3892_1 83406.HDN1F_01190 4.01e-28 112.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1J4D3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2699 PALP,Thr_dehydrat_C k141_455_1 367336.OM2255_12617 5.7e-89 288.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family soxA - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_3267_2 1000565.METUNv1_03656 1.1e-51 164.0 COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,2KWNM@206389|Rhodocyclales 206389|Rhodocyclales C ferredoxin - - - - - - - - - - - - 2Fe-2S_thioredx k141_10929_1 247634.GPB2148_3643 1.97e-68 225.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1J4N5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_1834_1 1278309.KB907099_gene3095 1.15e-85 270.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XHR3@135619|Oceanospirillales 135619|Oceanospirillales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_1834_2 1122599.AUGR01000002_gene3434 3.02e-199 560.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XIS5@135619|Oceanospirillales 135619|Oceanospirillales C alcohol dehydrogenase - - - ko:K19954 - - - - ko00000,ko01000 - - - Fe-ADH k141_5331_1 29486.NJ56_03305 0.000743 42.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,41DV7@629|Yersinia 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECO26_1355.ECO26_0095 Dala_Dala_lig_C,Dala_Dala_lig_N k141_5331_2 472759.Nhal_0494 5.8e-35 130.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1X2GI@135613|Chromatiales 135613|Chromatiales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_8766_1 371731.Rsw2DRAFT_1204 5.45e-105 329.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,1FAZS@1060|Rhodobacter 28211|Alphaproteobacteria M TIGRFAM penicillin-binding protein, 1A family mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_21386_1 105559.Nwat_0029 1.88e-117 352.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_13019_1 1278309.KB907103_gene1029 2.79e-68 223.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XH36@135619|Oceanospirillales 135619|Oceanospirillales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_13019_2 945543.VIBR0546_10279 1.27e-46 153.0 COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1XY0M@135623|Vibrionales 135623|Vibrionales O COG0695 Glutaredoxin and related proteins - - - - - - - - - - - - GST_N_3,Glutaredoxin k141_13019_3 1278309.KB907103_gene1027 3.08e-75 231.0 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1XK4N@135619|Oceanospirillales 135619|Oceanospirillales T Bacterial SH3 domain homologues - - - - - - - - - - - - SH3_3 k141_4644_1 1237149.C900_02768 2.75e-101 308.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia 976|Bacteroidetes S Oxygen tolerance - - - - - - - - - - - - BatD k141_13703_1 426114.THI_1334 1.17e-07 53.9 COG1999@1|root,COG1999@2|Bacteria,1RKIP@1224|Proteobacteria,2VS9B@28216|Betaproteobacteria,1KPJD@119065|unclassified Burkholderiales 28216|Betaproteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_13703_2 1247726.MIM_c10260 2.79e-15 77.4 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,2VP9I@28216|Betaproteobacteria,3T2BI@506|Alcaligenaceae 28216|Betaproteobacteria S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_1163_1 1278309.KB907101_gene670 0.0 978.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XHTN@135619|Oceanospirillales 135619|Oceanospirillales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_1163_2 1278309.KB907101_gene671 2.06e-54 179.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XH2T@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_16436_2 314278.NB231_00760 1.66e-141 410.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1WWUX@135613|Chromatiales 135613|Chromatiales P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_16436_3 1121918.ARWE01000001_gene3640 1.84e-161 462.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2WMH9@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_10930_1 1266914.ATUK01000002_gene485 2.21e-58 193.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales 135613|Chromatiales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_17144_2 1279015.KB908458_gene2510 4.19e-08 53.1 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1Y3ZB@135624|Aeromonadales 135624|Aeromonadales E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_7407_1 1245471.PCA10_36030 9.57e-31 121.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1YD12@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c k141_7407_2 754476.Q7A_323 4.78e-29 112.0 COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1NPHH@1224|Proteobacteria,1RR8S@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator receiver - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_22050_1 1432055.GLUCORHAEAF1_00455 0.000218 49.3 COG0596@1|root,COG0596@2|Bacteria,1QVJD@1224|Proteobacteria,2U3TI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Serine aminopeptidase, S33 - - 3.5.1.106 ko:K15357 ko00760,ko01120,map00760,map01120 M00622 R09126 RC00323,RC02431 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_13704_1 396588.Tgr7_1848 5.37e-69 222.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales 135613|Chromatiales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_1164_2 95619.PM1_0201005 2.12e-70 218.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_8171_1 93220.LV28_03130 1.35e-09 57.8 COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2VP16@28216|Betaproteobacteria,1K0AZ@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) astB - 3.5.3.23 ko:K01484 ko00330,ko01100,map00330,map01100 - R04189 RC00024 ko00000,ko00001,ko01000 - - - AstB k141_8171_2 1288826.MSNKSG1_11558 0.0 967.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,464KR@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD GO:0003674,GO:0003824,GO:0004029,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c20030,iEcHS_1320.EcHS_A1829,ic_1306.c2146 Aldedh k141_8171_3 1288826.MSNKSG1_11563 2.09e-265 727.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,469DX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG3138 Arginine ornithine N-succinyltransferase beta subunit astA - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - iE2348C_1286.E2348C_1875 AstA k141_8171_4 1288826.MSNKSG1_11568 2.62e-238 655.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,4661T@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG3138 Arginine ornithine N-succinyltransferase beta subunit - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_8171_5 1288826.MSNKSG1_11573 4.15e-298 812.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,464Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG4992 Ornithine acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006553,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009058,GO:0009064,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 ko:K00821,ko:K00840 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04217,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSFV_1184.SFV_3365,iSF_1195.SF3378,iSFxv_1172.SFxv_3689,iSSON_1240.SSON_3490,iS_1188.S4385 Aminotran_3 k141_8171_6 1288826.MSNKSG1_11578 1.56e-71 228.0 COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,1T2N1@1236|Gammaproteobacteria,465DB@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - GIY-YIG,RNase_T,VRR_NUC k141_15055_2 1163617.SCD_n02112 1.2e-39 141.0 COG3448@1|root,COG3448@2|Bacteria,1QUQ5@1224|Proteobacteria,2WGXX@28216|Betaproteobacteria 28216|Betaproteobacteria T CBS domain containing protein - - - - - - - - - - - - CBS k141_15055_3 713586.KB900536_gene3002 5.88e-70 228.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales 135613|Chromatiales P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_12328_1 1288826.MSNKSG1_02569 7.51e-95 286.0 COG4372@1|root,COG4372@2|Bacteria,1MX74@1224|Proteobacteria,1RMWF@1236|Gammaproteobacteria,466QI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transposase - - - - - - - - - - - - - k141_12328_2 1288826.MSNKSG1_02564 3.55e-126 377.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_6659_2 396588.Tgr7_1528 4.05e-41 148.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1WYRX@135613|Chromatiales 135613|Chromatiales S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC k141_457_1 1278309.KB907102_gene81 4.76e-142 415.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XHC9@135619|Oceanospirillales 135619|Oceanospirillales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_5332_2 640081.Dsui_2303 1.05e-23 99.0 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,2KWF3@206389|Rhodocyclales 206389|Rhodocyclales S Cobalt uptake substrate-specific transmembrane region - - - - - - - - - - - - CbiM k141_14329_1 1168067.JAGP01000001_gene1163 3.66e-117 351.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,460CE@72273|Thiotrichales 72273|Thiotrichales G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_16437_1 857087.Metme_3860 4.36e-89 268.0 COG2265@1|root,COG2265@2|Bacteria,1QV4X@1224|Proteobacteria,1S273@1236|Gammaproteobacteria,1XFHH@135618|Methylococcales 135618|Methylococcales J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_13705_1 1123517.JOMR01000001_gene414 7.87e-62 199.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,4602A@72273|Thiotrichales 72273|Thiotrichales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_3376_3 1472418.BBJC01000004_gene2104 8.88e-77 237.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_3376_4 314262.MED193_10998 6.61e-43 154.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,2P2ET@2433|Roseobacter 28211|Alphaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_13159_1 305700.B447_08423 7.18e-08 56.6 COG3240@1|root,COG3240@2|Bacteria,1MWDI@1224|Proteobacteria,2VTBY@28216|Betaproteobacteria,2KXBE@206389|Rhodocyclales 206389|Rhodocyclales I GDSL-like Lipase/Acylhydrolase - - - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Lipase_GDSL,VPEP k141_13159_2 1288826.MSNKSG1_11178 9.33e-95 290.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,4651E@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2223 Nitrate nitrite transporter narM - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_22184_1 1288826.MSNKSG1_10088 1.32e-167 491.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,4642Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_6768_1 717773.Thicy_0275 2.04e-80 247.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales 72273|Thiotrichales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_8868_1 391615.ABSJ01000051_gene1098 2.53e-37 131.0 COG1652@1|root,COG1652@2|Bacteria,1NKUE@1224|Proteobacteria 1224|Proteobacteria S LysM domain - - - - - - - - - - - - DUF4398,LysM k141_8868_3 443152.MDG893_09426 1.66e-11 60.5 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_10326_1 1163617.SCD_n02930 4.72e-97 291.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria 28216|Betaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k141_10326_2 1123399.AQVE01000002_gene2275 1.01e-22 94.4 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_10326_3 765912.Thimo_2704 4.36e-76 240.0 COG0547@1|root,COG0547@2|Bacteria,1QDR6@1224|Proteobacteria,1T9UH@1236|Gammaproteobacteria,1WW56@135613|Chromatiales 135613|Chromatiales E PFAM Glycosyl transferase, family - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_7537_2 765910.MARPU_11880 8.46e-58 182.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1WYPS@135613|Chromatiales 135613|Chromatiales O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR k141_5475_2 1122197.ATWI01000008_gene3139 5.55e-18 79.3 2D06H@1|root,32T7Y@2|Bacteria,1RI8P@1224|Proteobacteria,1T5IE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8288_1 1278309.KB907101_gene449 1.94e-97 285.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XJUJ@135619|Oceanospirillales 135619|Oceanospirillales O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_16574_1 1177154.Y5S_01704 3.73e-83 279.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_4782_1 697282.Mettu_3561 1.72e-131 382.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XDKU@135618|Methylococcales 135618|Methylococcales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_18050_1 670292.JH26_01450 5.33e-97 288.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,1JWHD@119045|Methylobacteriaceae 28211|Alphaproteobacteria I Coenzyme A transferase catI - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_3377_1 870967.VIS19158_21843 1.05e-83 272.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XUIR@135623|Vibrionales 135623|Vibrionales L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_15933_1 1279019.ARQK01000035_gene1554 1.91e-117 348.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15933_2 551789.ATVJ01000001_gene1827 1.74e-06 49.7 COG1917@1|root,COG1917@2|Bacteria,1PVH1@1224|Proteobacteria,2V6W5@28211|Alphaproteobacteria,43YDZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 k141_9557_1 985867.AEWF01000004_gene217 2.96e-15 72.4 COG1366@1|root,COG1366@2|Bacteria,1NGGT@1224|Proteobacteria,2UHDV@28211|Alphaproteobacteria,47G88@766|Rickettsiales 766|Rickettsiales T STAS domain - - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS_2 k141_9557_2 1122137.AQXF01000004_gene1542 1.18e-09 58.5 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2U0XK@28211|Alphaproteobacteria 28211|Alphaproteobacteria NT methyl-accepting chemotaxis protein - - - - - - - - - - - - MCPsignal k141_11701_1 546271.Selsp_0388 0.000476 46.6 COG2870@1|root,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,4H1UR@909932|Negativicutes 909932|Negativicutes M Bifunctional protein rfaE - - - - - - - - - - - CTP_transf_like,PfkB k141_11701_2 1283300.ATXB01000001_gene479 1.04e-244 697.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1XDS7@135618|Methylococcales 135618|Methylococcales M Sucrose phosphate synthase, sucrose phosphatase-like - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1,S6PP k141_8289_1 1163407.UU7_10715 7.99e-22 90.9 COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,1S3D2@1236|Gammaproteobacteria,1X3MK@135614|Xanthomonadales 135614|Xanthomonadales S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 k141_8289_2 1211114.ALIP01000127_gene569 9.82e-44 156.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1X53V@135614|Xanthomonadales 135614|Xanthomonadales T gtp-binding protein typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_16575_1 1158150.KB906242_gene210 1.55e-45 167.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria,1X1UJ@135613|Chromatiales 135613|Chromatiales L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C k141_13161_1 983545.Glaag_4524 4.08e-59 200.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,465RT@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein - - - - - - - - - - - - OEP k141_12482_2 1123368.AUIS01000009_gene2461 6.59e-21 89.7 COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,1S6MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_2635_1 1121939.L861_21955 3.94e-27 107.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1XMCH@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09926 - - - - ko00000 - - - FixH k141_2635_2 396588.Tgr7_0635 5.86e-19 80.5 2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_20743_2 1042375.AFPL01000029_gene3387 4.17e-223 625.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_20743_3 744980.TRICHSKD4_0437 6.78e-29 112.0 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2UFJP@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_1960_1 1283300.ATXB01000002_gene3162 1.92e-40 145.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XDT6@135618|Methylococcales 135618|Methylococcales P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_1960_2 1123278.KB893554_gene3975 6.6e-181 518.0 COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47MBE@768503|Cytophagia 976|Bacteroidetes E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_1960_3 324602.Caur_2545 4.09e-61 209.0 2C8CV@1|root,2Z8NV@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3095) MA20_06625 - - - - - - - - - - - DUF3095 k141_1960_4 1123368.AUIS01000004_gene122 2.74e-08 56.2 2EM8V@1|root,33EY0@2|Bacteria,1NJMD@1224|Proteobacteria,1SIVI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3135) - - - - - - - - - - - - DUF3135 k141_1960_5 240016.ABIZ01000001_gene2542 3.25e-06 55.1 COG0745@1|root,COG0745@2|Bacteria,46TFQ@74201|Verrucomicrobia 74201|Verrucomicrobia T Helix-turn-helix domain - - - - - - - - - - - - HTH_17,Response_reg k141_20020_1 314287.GB2207_10658 2.23e-21 94.7 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_20020_2 930169.B5T_00457 2.55e-14 68.6 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1XPEX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_13842_1 2340.JV46_05460 1.37e-31 123.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1J4NX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P von Willebrand factor (vWF) type A domain norD - - ko:K02448 - - R00294 RC02794 ko00000 3.D.4.10 - - VWA,VWA_2 k141_13842_2 1278309.KB907109_gene3277 6.09e-121 351.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,1XKN4@135619|Oceanospirillales 135619|Oceanospirillales K Crp-like helix-turn-helix domain - - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_13842_3 317025.Tcr_1057 1.21e-37 126.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,462YA@72273|Thiotrichales 72273|Thiotrichales K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_13842_4 1278309.KB907099_gene3123 9.54e-143 412.0 2C55T@1|root,2ZARV@2|Bacteria,1R77G@1224|Proteobacteria 1224|Proteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 k141_1298_1 1288826.MSNKSG1_09503 3.63e-70 215.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria,466CE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) ycgM - - - - - - - - - - - FAA_hydrolase k141_1298_2 1288826.MSNKSG1_09498 7.73e-125 355.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S4VM@1236|Gammaproteobacteria,46DFY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - iUTI89_1310.UTI89_C0496,ic_1306.c0588 Pribosyltran k141_1298_3 1288826.MSNKSG1_09493 3.11e-289 792.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,464EG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2252 Permeases purP - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k141_1298_4 1288826.MSNKSG1_09488 3.88e-144 406.0 COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,4684J@72275|Alteromonadaceae 1236|Gammaproteobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 k141_1298_5 1288826.MSNKSG1_09483 1.12e-126 361.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K21701 - - - - ko00000,ko03000 - - - Arabinose_bd,HTH_18 k141_1298_6 1288826.MSNKSG1_09478 3.54e-230 634.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,1SYCA@1236|Gammaproteobacteria,464Q1@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k141_1298_7 1288826.MSNKSG1_09473 0.0 1221.0 COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQD3@1236|Gammaproteobacteria,464J8@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.48 ko:K02182,ko:K13776 ko00281,map00281 - R08088 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_8301_2 207954.MED92_15043 5.33e-261 721.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHXR@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_8301_3 207954.MED92_15048 8.75e-22 89.0 COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,1S44W@1236|Gammaproteobacteria,1XK8V@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_5482_1 1278309.KB907101_gene283 9.58e-112 327.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XIBX@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_5482_2 1278309.KB907101_gene284 4.32e-87 258.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1XJUV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 k141_5482_3 1278309.KB907101_gene285 3.77e-155 439.0 COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,1RQIM@1236|Gammaproteobacteria,1XIIF@135619|Oceanospirillales 135619|Oceanospirillales I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_5482_4 264198.Reut_A3255 1.45e-25 102.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,1K740@119060|Burkholderiaceae 28216|Betaproteobacteria S Sulfur oxidation protein SoxY soxY - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_5482_5 1278309.KB907101_gene290 1.4e-34 121.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1XKWU@135619|Oceanospirillales 135619|Oceanospirillales S Sulphur oxidation protein SoxZ - - - - - - - - - - - - SoxZ k141_5482_6 1278309.KB907101_gene294 1.49e-98 293.0 2E24M@1|root,32XBQ@2|Bacteria,1N4K9@1224|Proteobacteria,1S9J9@1236|Gammaproteobacteria,1XKV9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5482_7 1278309.KB907101_gene295 3.85e-99 290.0 COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,1XK0G@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09906 - - - - ko00000,ko01000,ko03012 - - - EpmC k141_5482_8 1244083.CSUNSWCD_1138 7.36e-25 101.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,42TJB@68525|delta/epsilon subdivisions,2YPS9@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S hmm pf04314 - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_5482_9 1278309.KB907101_gene297 7.85e-105 306.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1S3NG@1236|Gammaproteobacteria,1XJRX@135619|Oceanospirillales 135619|Oceanospirillales S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_8880_1 1385517.N800_09330 1.6e-39 135.0 COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,1S64Y@1236|Gammaproteobacteria,1X6S2@135614|Xanthomonadales 135614|Xanthomonadales S Microcystin-dependent protein - - - - - - - - - - - - Collar k141_8880_2 1005048.CFU_2232 1.4e-15 74.3 COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2VTJM@28216|Betaproteobacteria,474KF@75682|Oxalobacteraceae 28216|Betaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k141_17288_1 1288826.MSNKSG1_13202 1.18e-36 134.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1RZ5Q@1236|Gammaproteobacteria,46767@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_17288_2 1288826.MSNKSG1_13197 0.0 926.0 COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae 1236|Gammaproteobacteria S competence protein - - - - - - - - - - - - - k141_17288_3 1288826.MSNKSG1_13192 3.03e-191 544.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RSD8@1236|Gammaproteobacteria,465FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_21517_1 1121935.AQXX01000100_gene1276 2.51e-101 306.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XHUG@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_18065_1 1121374.KB891585_gene1870 1.28e-100 307.0 COG1819@1|root,COG1819@2|Bacteria,1QVV0@1224|Proteobacteria,1RQBP@1236|Gammaproteobacteria 1236|Gammaproteobacteria CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - - - - - - - - - - Glyco_trans_1_3 k141_16592_1 1318628.MARLIPOL_12739 1.02e-30 120.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,4683Q@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the GSP D family cpaC - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N k141_16592_2 1279015.KB908465_gene105 3.92e-05 48.1 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF k141_1315_1 870187.Thini_1508 1.01e-72 221.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,460RH@72273|Thiotrichales 72273|Thiotrichales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_1315_2 857087.Metme_2385 2.46e-55 179.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XE5E@135618|Methylococcales 135618|Methylococcales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_1965_1 1333507.AUTQ01000260_gene3657 8.98e-80 273.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,2Q2Z5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Alpha-2-Macroglobulin - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl k141_4794_1 1278309.KB907099_gene2545 1.17e-105 315.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XIF2@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_15950_1 1089548.KI783301_gene3392 7.03e-15 67.4 2EMP1@1|root,33FBF@2|Bacteria,1VKRU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_2649_1 1122599.AUGR01000014_gene588 1.64e-109 325.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1XN2Q@135619|Oceanospirillales 135619|Oceanospirillales C 4Fe-4S binding domain - - - - - - - - - - - - CCG,Fer4_8 k141_13167_1 1168067.JAGP01000001_gene359 1.88e-94 287.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,45ZMM@72273|Thiotrichales 72273|Thiotrichales F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_15155_2 991905.SL003B_2078 7.9e-13 71.6 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,4BQ7Y@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the complex I subunit 6 family nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_22190_1 1288826.MSNKSG1_05556 1.73e-141 405.0 COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,1SEI1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transport system periplasmic component - - - - - - - - - - - - ABC_sub_bind k141_22190_2 1288826.MSNKSG1_05561 0.0 1292.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RRFS@1236|Gammaproteobacteria,468B5@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_22190_3 626887.J057_21095 3.43e-45 157.0 COG2214@1|root,COG2214@2|Bacteria 2|Bacteria O Heat shock protein DnaJ domain protein - - - - - - - - - - - - DnaJ,RDD k141_22190_4 1288826.MSNKSG1_05576 1.82e-231 639.0 COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,1RN2S@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bile acid sodium symporter - - - ko:K14347 - - - - ko00000,ko02000,ko04147 2.A.93.1 - - SBF_like k141_22190_5 1288826.MSNKSG1_05581 1.11e-140 399.0 COG2186@1|root,COG2186@2|Bacteria,1RHPY@1224|Proteobacteria,1SYZQ@1236|Gammaproteobacteria,46CA0@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_22190_6 1288826.MSNKSG1_05586 0.0 978.0 COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPJY@1236|Gammaproteobacteria,4642J@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport - - - - - - - - - - - - Abhydrolase_3,FMO-like,K_oxygenase,Pyr_redox_3 k141_22190_7 1288826.MSNKSG1_05591 1.77e-208 577.0 COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,465ZG@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family nhaR - - ko:K03717 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_22190_8 1288826.MSNKSG1_05596 2.06e-75 240.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,469HG@72275|Alteromonadaceae 1236|Gammaproteobacteria CP Proton-conducting membrane transporter - - 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N k141_10342_3 205922.Pfl01_0336 2.66e-46 155.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1YNJ5@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_4150_1 765913.ThidrDRAFT_4411 4.69e-50 165.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RZY6@1236|Gammaproteobacteria,1WX9M@135613|Chromatiales 135613|Chromatiales U Part of a membrane complex involved in electron transport - - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_4150_2 765911.Thivi_3393 4.03e-17 82.4 COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,1RQ1E@1236|Gammaproteobacteria,1WW44@135613|Chromatiales 135613|Chromatiales T nitrogen fixation negative regulator NifL - - - - - - - - - - - - HATPase_c,PAS,PAS_9 k141_20179_1 1046724.KB889882_gene1832 1.23e-09 59.3 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae 1236|Gammaproteobacteria P molybdenum ABC transporter, periplasmic modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_20179_2 472759.Nhal_3767 7.24e-39 142.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales 135613|Chromatiales H PFAM Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_1404_2 713586.KB900536_gene2898 2.81e-175 499.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_9069_1 48698.ENSPFOP00000008155 0.000225 50.4 COG0457@1|root,KOG1124@2759|Eukaryota,39V6M@33154|Opisthokonta,3BF56@33208|Metazoa,3CWX3@33213|Bilateria,48B8W@7711|Chordata,493S6@7742|Vertebrata,4A0RZ@7898|Actinopterygii 33208|Metazoa S Translocase of outer mitochondrial membrane 34 TOMM34 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005829,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0031072,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070013,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0098588,GO:0098805 - ko:K17766 - - - - ko00000,ko03029 - - - TPR_1,TPR_2,TPR_8 k141_9069_2 1469557.JSWF01000030_gene3460 1.21e-43 154.0 COG1266@1|root,COG1266@2|Bacteria,4NWFF@976|Bacteroidetes 976|Bacteroidetes S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_9069_3 443143.GM18_2506 7.29e-50 170.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2WIZC@28221|Deltaproteobacteria,43S0U@69541|Desulfuromonadales 28221|Deltaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_20223_1 765911.Thivi_4550 1.88e-13 75.1 COG0501@1|root,COG4969@1|root,COG0501@2|Bacteria,COG4969@2|Bacteria,1R47C@1224|Proteobacteria,1RPRU@1236|Gammaproteobacteria,1X0GS@135613|Chromatiales 135613|Chromatiales O PFAM Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 k141_20922_1 1049564.TevJSym_al00340 4.99e-106 316.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1JA5R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O AIR synthase related protein, N-terminal domain hypE GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_710_1 768671.ThimaDRAFT_4548 4.02e-61 198.0 COG1073@1|root,COG1073@2|Bacteria,1R76C@1224|Proteobacteria,1RR34@1236|Gammaproteobacteria,1X0RN@135613|Chromatiales 135613|Chromatiales S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_8378_1 95619.PM1_0212795 1.9e-74 236.0 COG4977@1|root,COG4977@2|Bacteria,1NRX7@1224|Proteobacteria,1S05D@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_14655_1 1288826.MSNKSG1_07588 7.8e-253 700.0 COG2067@1|root,COG2067@2|Bacteria,1N0NZ@1224|Proteobacteria,1S0U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X k141_15351_1 1286631.X805_19580 3.53e-37 132.0 COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,2WI0N@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_15351_2 259536.Psyc_0546 1.47e-27 112.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,3NSXE@468|Moraxellaceae 1236|Gammaproteobacteria P Sodium proton antiporter, CPA1 family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_18132_1 377629.TERTU_1962 1.62e-24 95.9 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,2PNP2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S ATP-dependent Clp protease adaptor protein ClpS clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_11864_2 1278309.KB907099_gene2650 3.63e-33 125.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIWJ@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_6980_1 1278309.KB907108_gene1586 1.88e-153 441.0 2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria,1XNQZ@135619|Oceanospirillales 135619|Oceanospirillales S Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - DUF1329 k141_20224_2 555778.Hneap_0795 2.92e-34 121.0 COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,1S85W@1236|Gammaproteobacteria,1X274@135613|Chromatiales 135613|Chromatiales K NikR C terminal nickel binding domain - - - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 k141_19534_1 1278309.KB907101_gene734 3.34e-24 96.3 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XJSZ@135619|Oceanospirillales 135619|Oceanospirillales E Lysine exporter protein (LysE - - - - - - - - - - - - LysE k141_13265_1 580332.Slit_1177 6e-80 263.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria 28216|Betaproteobacteria M Penicillin-binding protein 1c pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase k141_17435_1 1286106.MPL1_07792 1.03e-60 199.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_13952_2 1163407.UU7_14435 1.71e-67 208.0 2BWTW@1|root,315N7@2|Bacteria,1RABY@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_20924_1 207954.MED92_10324 3.16e-68 222.0 COG0477@1|root,COG2814@2|Bacteria,1R8QG@1224|Proteobacteria 1224|Proteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_2795_1 1278309.KB907110_gene3204 1.4e-138 417.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1XIF3@135619|Oceanospirillales 135619|Oceanospirillales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_16742_1 351348.Maqu_0136 5.76e-173 514.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,464J4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_711_1 1278309.KB907112_gene3337 9.83e-92 270.0 COG0589@1|root,COG0589@2|Bacteria,1RF81@1224|Proteobacteria,1S4QK@1236|Gammaproteobacteria,1XJIG@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_19535_1 395494.Galf_2337 3.41e-43 153.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2W931@28216|Betaproteobacteria,44WM2@713636|Nitrosomonadales 28216|Betaproteobacteria H PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_15352_1 1472418.BBJC01000004_gene1855 6.73e-69 230.0 COG0120@1|root,COG0534@1|root,COG0120@2|Bacteria,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Mate efflux family protein norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_15352_2 398580.Dshi_2737 1.15e-20 90.1 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_18133_1 243277.VC_1273 1.96e-34 129.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XV1B@135623|Vibrionales 135623|Vibrionales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_20225_1 1122604.JONR01000001_gene1738 1.07e-111 336.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_11865_1 194439.CT1683 1.91e-23 100.0 COG0474@1|root,COG0474@2|Bacteria 2|Bacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_1405_1 1323663.AROI01000010_gene3262 4.04e-33 119.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325 CDP-OH_P_transf k141_1405_2 349124.Hhal_0022 1.59e-54 187.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_20925_1 1121374.KB891585_gene2378 1.2e-58 202.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_13266_1 765911.Thivi_0673 3.79e-22 95.9 COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG2984@1|root,COG3290@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2984@2|Bacteria,COG3290@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K10715,ko:K20974 ko02020,ko02024,ko02025,map02020,map02024,map02025 M00517,M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_13266_2 159087.Daro_3976 4.92e-54 178.0 COG0834@1|root,COG0834@2|Bacteria,1R7DC@1224|Proteobacteria,2VP65@28216|Betaproteobacteria 28216|Betaproteobacteria ET Amino Acid - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_3494_1 1288826.MSNKSG1_13677 0.0 1050.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_3494_2 1380387.JADM01000002_gene2068 3.42e-06 47.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1XPEX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_3494_3 1288826.MSNKSG1_13687 1.94e-103 299.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,46779@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-binding protein copG - - - - - - - - - - - DUF411 k141_3494_4 1288826.MSNKSG1_13692 0.0 1103.0 COG2199@1|root,COG3850@1|root,COG4564@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,COG4564@2|Bacteria,1QXG6@1224|Proteobacteria,1T3BA@1236|Gammaproteobacteria,469Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,HAMP k141_3494_5 1288826.MSNKSG1_13697 2.98e-142 409.0 COG5497@1|root,COG5497@2|Bacteria,1QXG7@1224|Proteobacteria 1224|Proteobacteria S secreted protein - - - - - - - - - - - - - k141_9070_2 95619.PM1_0207685 2.53e-132 397.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K11914,ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko02044,ko03000 - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_14656_1 1380391.JIAS01000019_gene1155 1.43e-29 116.0 COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2JTER@204441|Rhodospirillales 204441|Rhodospirillales L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_14656_2 338966.Ppro_3708 3.71e-63 204.0 COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria 1224|Proteobacteria L Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_16743_1 765698.Mesci_3835 5.22e-61 203.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k141_20926_1 1286632.P278_27820 1.72e-70 225.0 COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1HZT9@117743|Flavobacteriia 976|Bacteroidetes P cytochrome C peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C k141_20226_2 396588.Tgr7_2226 2.21e-75 231.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales 135613|Chromatiales O Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_4890_1 172088.AUGA01000006_gene8149 3e-58 197.0 COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,3JRTU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 k141_4890_2 335659.S23_10540 1.72e-96 287.0 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,3JRHZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_3495_1 1122137.AQXF01000003_gene2470 3.83e-80 246.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Rod shape-determining protein (MreB) mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_16041_1 1278309.KB907102_gene211 2.42e-41 139.0 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,1XMJA@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16041_2 1278309.KB907102_gene212 3.24e-07 50.8 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XHGP@135619|Oceanospirillales 135619|Oceanospirillales S ATPase components of ABC transporters with duplicated ATPase domains - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_14657_1 998674.ATTE01000001_gene4005 3.35e-59 196.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,461UD@72273|Thiotrichales 72273|Thiotrichales V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_3 k141_7683_1 443152.MDG893_07395 0.0 1040.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal k141_6285_1 2340.JV46_16340 6.37e-115 357.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1J4YE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_6285_2 395964.KE386496_gene1769 4.12e-06 50.1 COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,2U7D2@28211|Alphaproteobacteria,3NBI7@45404|Beijerinckiaceae 28211|Alphaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_13953_1 1265503.KB905160_gene2462 2.89e-32 115.0 2C7FC@1|root,32S1T@2|Bacteria,1N1DJ@1224|Proteobacteria,1S96F@1236|Gammaproteobacteria,2Q77S@267889|Colwelliaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13953_2 95619.PM1_0216130 3.79e-59 192.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 k141_11867_1 1297570.MESS4_370046 1.01e-51 183.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,43JE0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding k141_10463_1 1278309.KB907100_gene1998 1.04e-151 433.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1XH3V@135619|Oceanospirillales 135619|Oceanospirillales NU Pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_10463_2 1278309.KB907100_gene1999 0.0 1056.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XHH3@135619|Oceanospirillales 135619|Oceanospirillales M penicillin-binding protein mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_5587_1 1288826.MSNKSG1_13247 7.26e-53 177.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,1RR20@1236|Gammaproteobacteria,4656R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 k141_5587_2 1288826.MSNKSG1_13242 0.0 1281.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,4647A@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_5587_3 1288826.MSNKSG1_13237 4.68e-168 469.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,465DT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K02483,ko:K07663 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_5587_4 1288826.MSNKSG1_13232 8.7e-244 686.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_8379_1 1123393.KB891316_gene1507 4.6e-11 62.4 COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,2VHKR@28216|Betaproteobacteria,1KSKE@119069|Hydrogenophilales 119069|Hydrogenophilales K WYL domain - - - - - - - - - - - - WYL k141_8379_2 795666.MW7_2364 1.08e-15 75.9 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,1K09V@119060|Burkholderiaceae 28216|Betaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_2109_1 1288826.MSNKSG1_09623 1.88e-147 430.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_15353_1 266809.PM03_05825 5.05e-156 444.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2TT7X@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_712_1 1278309.KB907100_gene1808 7.63e-201 589.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XI0M@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_1406_1 1238190.AMQY01000013_gene1159 8.41e-23 103.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XHIB@135619|Oceanospirillales 135619|Oceanospirillales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7 k141_1406_2 765911.Thivi_0535 6.79e-25 99.4 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales 135613|Chromatiales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase k141_10_1 1121434.AULY01000009_gene1914 2.41e-59 186.0 COG0599@1|root,COG0599@2|Bacteria,1RH7V@1224|Proteobacteria,42SWM@68525|delta/epsilon subdivisions,2WPMD@28221|Deltaproteobacteria,2MGGE@213115|Desulfovibrionales 28221|Deltaproteobacteria S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_4191_1 1278309.KB907107_gene1709 1.61e-133 395.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1XIUW@135619|Oceanospirillales 135619|Oceanospirillales N SRP54-type protein, GTPase domain - - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_18134_1 1298867.AUES01000051_gene4507 2.82e-93 295.0 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U22Z@28211|Alphaproteobacteria,3K3DU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23 k141_18134_2 1353537.TP2_00595 3.51e-56 194.0 COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidase, M50 family - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,PqqD k141_9071_1 74547.PMT_1203 1.36e-28 115.0 28IUD@1|root,2Z8T4@2|Bacteria,1GC55@1117|Cyanobacteria,1MKPD@1212|Prochloraceae 1117|Cyanobacteria S Alternative locus ID csoS2 - - - - - - - - - - - CsoS2_M k141_9071_2 768671.ThimaDRAFT_4725 3.31e-19 89.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA k141_2796_1 583355.Caka_2796 1.89e-26 99.4 COG2841@1|root,COG2841@2|Bacteria 2|Bacteria S Protein of unknown function (DUF465) VPA0402 - - ko:K09794 - - - - ko00000 - - - DUF465 k141_18836_1 298386.PBPRB0650 1.05e-117 362.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1XU9K@135623|Vibrionales 1224|Proteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism - - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_12560_1 95619.PM1_0209840 1.3e-112 355.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Exporters of the RND superfamily IV02_10640 - - ko:K07003 - - - - ko00000 - - - MMPL k141_6981_1 983545.Glaag_0853 6.73e-23 99.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_6981_2 765910.MARPU_14185 5.51e-166 478.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1WWSU@135613|Chromatiales 135613|Chromatiales E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_6981_3 589873.EP13_14410 3.58e-35 124.0 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,467U6@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the Nudix hydrolase family mutT GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129 NUDIX,NUDIX_4,TMP-TENI k141_11868_2 391624.OIHEL45_07645 3.59e-72 223.0 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,2TRJD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - SLT k141_20227_2 1238190.AMQY01000025_gene27 5.62e-29 108.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XKKG@135619|Oceanospirillales 135619|Oceanospirillales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_7705_2 1269813.ATUL01000003_gene2356 1.21e-23 102.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales 135613|Chromatiales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_5603_1 1227499.C493_11637 1.94e-27 113.0 COG1840@1|root,arCOG00227@2157|Archaea,2XUIC@28890|Euryarchaeota,23S84@183963|Halobacteria 183963|Halobacteria P ABC-type Fe3 transport system, periplasmic component sfuA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_6,SBP_bac_8 k141_17563_1 349102.Rsph17025_2207 1.35e-108 334.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,1FB1P@1060|Rhodobacter 28211|Alphaproteobacteria O TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_116_2 90813.JQMT01000001_gene1820 5.09e-84 265.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,463SJ@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_16880_2 652103.Rpdx1_4311 2.61e-98 294.0 COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2TU3M@28211|Alphaproteobacteria,3JQWF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GM ABC transporter rfbE - - ko:K01990,ko:K09691 ko02010,map02010 M00250,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 - - ABC_tran,Wzt_C k141_18265_2 1040986.ATYO01000006_gene356 7.03e-60 191.0 COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2U5HX@28211|Alphaproteobacteria,43KT6@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_19660_1 1049564.TevJSym_ae00930 3.67e-94 283.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4CK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_17564_1 1208323.B30_02335 3.7e-47 156.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_17564_2 412597.AEPN01000001_gene3077 2.48e-49 169.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,2PVA6@265|Paracoccus 28211|Alphaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM k141_14103_1 765914.ThisiDRAFT_0484 1.11e-90 278.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1WWFA@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydratase - - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k141_14103_2 391615.ABSJ01000054_gene1432 2.05e-55 184.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1J5JV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Aminotransferase class I and II hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_2935_1 395493.BegalDRAFT_3417 1.03e-144 417.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,460AH@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_117_1 395493.BegalDRAFT_2551 3.99e-129 384.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_8508_1 626887.J057_14890 1.16e-26 100.0 2ASWM@1|root,31IC3@2|Bacteria,1N1F9@1224|Proteobacteria,1S798@1236|Gammaproteobacteria,46788@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3010) SO2839 - - - - - - - - - - - DUF3010 k141_8508_2 1288826.MSNKSG1_10538 4.13e-68 206.0 COG0526@1|root,COG0526@2|Bacteria,1N9U2@1224|Proteobacteria,1SBER@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Thioredoxin - - - - - - - - - - - - Thioredoxin k141_8508_3 1288826.MSNKSG1_10543 2.53e-206 571.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,465NH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_8508_5 443152.MDG893_03015 1.47e-113 332.0 2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,465TE@72275|Alteromonadaceae 1236|Gammaproteobacteria S 5'-nucleotidase - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5-nucleotidase k141_7831_1 713586.KB900536_gene2226 9.91e-216 627.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_13408_1 1278309.KB907099_gene2379 6.55e-221 654.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XHFM@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 k141_9185_1 1245471.PCA10_21880 2.7e-83 298.0 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1YFZG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_9185_2 1110502.TMO_3301 1.9e-63 203.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,2JS1J@204441|Rhodospirillales 204441|Rhodospirillales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_2227_2 1288826.MSNKSG1_09663 5.24e-48 154.0 COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria,1S8ZM@1236|Gammaproteobacteria,468UP@72275|Alteromonadaceae 1236|Gammaproteobacteria P Multiple resistance and pH regulation protein F phaF - - ko:K05563 - - - - ko00000,ko02000 2.A.63.1 - - MrpF_PhaF k141_2227_3 1288826.MSNKSG1_09668 3.83e-69 209.0 COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,1S8TM@1236|Gammaproteobacteria,46818@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1320 Multisubunit Na H antiporter, MnhG subunit phaG - - ko:K05564,ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB k141_2227_4 1288826.MSNKSG1_09673 9.12e-62 189.0 COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,4680M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions ppnP GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 - R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 - - - DUF1255 k141_2227_5 1288826.MSNKSG1_09678 0.0 1099.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,46625@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_2227_6 1318628.MARLIPOL_02245 6.03e-295 810.0 COG3211@1|root,COG3211@2|Bacteria,1QY0R@1224|Proteobacteria,1S1HN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF839) - - - - - - - - - - - - DUF839,PD40 k141_2227_7 1318628.MARLIPOL_02250 7.82e-96 295.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae 1236|Gammaproteobacteria P alkaline phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N k141_14801_1 400668.Mmwyl1_3864 6.99e-58 203.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RZC1@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_14801_2 646529.Desaci_3750 4.93e-20 99.4 COG0840@1|root,COG0840@2|Bacteria,1TRIC@1239|Firmicutes,24BC0@186801|Clostridia 186801|Clostridia NT PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CZB,MCPsignal k141_14801_3 1232683.ADIMK_3582 1.59e-88 272.0 COG2202@1|root,COG2202@2|Bacteria,1R24Q@1224|Proteobacteria,1T5GT@1236|Gammaproteobacteria,46835@72275|Alteromonadaceae 1236|Gammaproteobacteria T Nitrate and nitrite sensing - - - - - - - - - - - - NIT k141_14801_4 1395571.TMS3_0114890 4.17e-153 447.0 COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,1SRMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_14801_5 1122201.AUAZ01000001_gene2229 3.5e-151 438.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 k141_15518_1 1123514.KB905899_gene1192 4.33e-35 121.0 2C3Q0@1|root,334WS@2|Bacteria,1NBS8@1224|Proteobacteria,1SE5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - IV02_14570 - - - - - - - - - - - - k141_15518_2 443144.GM21_0708 5.11e-96 289.0 COG3618@1|root,COG3618@2|Bacteria,1PF81@1224|Proteobacteria,42Z8K@68525|delta/epsilon subdivisions,2WU9E@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_12006_1 1232683.ADIMK_0702 2.24e-81 256.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RQ89@1236|Gammaproteobacteria,46A5X@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase puuB1 - - - - - - - - - - iJN746.PP_5257 DAO k141_12006_2 1232683.ADIMK_0701 1.62e-107 320.0 COG0583@1|root,COG0583@2|Bacteria,1RC4N@1224|Proteobacteria,1S2X6@1236|Gammaproteobacteria,467Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_12006_3 1232683.ADIMK_0700 1.49e-189 541.0 COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,1RY9G@1236|Gammaproteobacteria,469T8@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family pcd - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18976_1 1266925.JHVX01000009_gene28 1.41e-35 131.0 COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,2WFIE@28216|Betaproteobacteria,372YN@32003|Nitrosomonadales 28216|Betaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_18976_2 1125712.HMPREF1316_2471 4.55e-05 49.3 COG0745@1|root,COG0745@2|Bacteria,2IGM3@201174|Actinobacteria,4CV5P@84998|Coriobacteriia 84998|Coriobacteriia K response regulator receiver - - - - - - - - - - - - Response_reg,Trans_reg_C k141_18976_3 1392540.P256_02204 1.44e-21 95.1 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,3NJR5@468|Moraxellaceae 1236|Gammaproteobacteria NU Type II secretion system (T2SS), protein E, N-terminal domain gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_21756_1 857087.Metme_1801 6.66e-27 107.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1XEKP@135618|Methylococcales 135618|Methylococcales S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_21756_2 289376.THEYE_A0811 0.000568 49.7 COG1597@1|root,COG1597@2|Bacteria,3J1CE@40117|Nitrospirae 40117|Nitrospirae I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat k141_15540_1 1266909.AUAG01000022_gene1708 1.31e-05 46.2 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_18291_1 697282.Mettu_2134 1.76e-68 216.0 COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,1S9D2@1236|Gammaproteobacteria,1XFNX@135618|Methylococcales 135618|Methylococcales M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_3668_1 1121878.AUGL01000011_gene821 5.95e-38 137.0 COG0454@1|root,COG0456@2|Bacteria,1R407@1224|Proteobacteria,1RPJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K histone acetyltransferase HPA2 and related acetyltransferases yiiD GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C k141_3668_2 857087.Metme_0115 8.75e-79 241.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_149_1 396588.Tgr7_0127 3.35e-76 243.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_21139_1 1502852.FG94_01382 1.38e-29 117.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,4725Y@75682|Oxalobacteraceae 28216|Betaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI k141_21139_2 105559.Nwat_0349 1.03e-105 330.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_19690_1 1232410.KI421422_gene2026 9.94e-63 199.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,43SF9@69541|Desulfuromonadales 28221|Deltaproteobacteria L endonuclease III nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_17587_1 367336.OM2255_13002 5.76e-147 419.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_5776_1 305700.B447_06667 8.57e-216 619.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VK3H@28216|Betaproteobacteria,2KXRD@206389|Rhodocyclales 206389|Rhodocyclales J Amidase - - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_20407_1 1278309.KB907099_gene2436 1.64e-163 462.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1XHTW@135619|Oceanospirillales 135619|Oceanospirillales EF Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_20407_2 118161.KB235922_gene4056 1.29e-62 200.0 COG3145@1|root,COG3145@2|Bacteria,1G503@1117|Cyanobacteria,3VMDY@52604|Pleurocapsales 1117|Cyanobacteria L 2OG-Fe(II) oxygenase superfamily alkB - - - - - - - - - - - 2OG-FeII_Oxy_2 k141_20407_3 1278309.KB907099_gene2433 6.29e-147 417.0 COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,1RMRT@1236|Gammaproteobacteria,1XIN5@135619|Oceanospirillales 135619|Oceanospirillales C nitroreductase - - - ko:K10678 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_20407_4 349521.HCH_04687 8.13e-65 207.0 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,1XQK4@135619|Oceanospirillales 135619|Oceanospirillales L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k141_20407_5 675812.VHA_002118 2.94e-50 165.0 COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,1S22M@1236|Gammaproteobacteria,1XTSB@135623|Vibrionales 135623|Vibrionales N inhibitor of MCP methylation, homolog of CheC cheX - - ko:K03409 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheX k141_20407_6 1278309.KB907099_gene2429 1.64e-85 253.0 COG0369@1|root,COG0369@2|Bacteria,1QUX0@1224|Proteobacteria,1T24E@1236|Gammaproteobacteria,1XMC9@135619|Oceanospirillales 135619|Oceanospirillales P Nitric oxide synthase - - - - - - - - - - - - Flavodoxin_1 k141_4359_1 1278309.KB907105_gene1408 1.44e-79 250.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1XJ8D@135619|Oceanospirillales 135619|Oceanospirillales S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_4359_2 1278309.KB907105_gene1409 7.45e-162 460.0 COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,1XJBS@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_4359_3 1278309.KB907105_gene1410 4.44e-89 264.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1XK4G@135619|Oceanospirillales 135619|Oceanospirillales T Histidine phosphatase superfamily (branch 1) - - - ko:K08296 - - - - ko00000,ko01000 - - - CHAD,His_Phos_1 k141_4359_4 1278309.KB907105_gene1411 3.27e-179 513.0 COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,1RP80@1236|Gammaproteobacteria,1XH7C@135619|Oceanospirillales 135619|Oceanospirillales I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - 2.8.3.1 ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 - R00928,R01449,R05508 RC00012,RC00014,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans k141_15541_1 1278309.KB907099_gene2738 2.6e-20 87.4 COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1XHUT@135619|Oceanospirillales 135619|Oceanospirillales K LuxR family luxR - - - - - - - - - - - GerE,Response_reg k141_14831_1 314278.NB231_02073 3.37e-51 176.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1WXF1@135613|Chromatiales 135613|Chromatiales N PFAM GTP-binding signal recognition particle SRP54 G- domain - - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_14831_2 1163409.UUA_17085 1.02e-12 70.1 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1X3K0@135614|Xanthomonadales 135614|Xanthomonadales N flagellar flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_13428_1 105559.Nwat_0533 1.08e-48 167.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_9894_1 1232683.ADIMK_3203 3.06e-20 93.2 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,467K0@72275|Alteromonadaceae 1236|Gammaproteobacteria S AI-2E family transporter perM - - - - - - - - - - - AI-2E_transport k141_9894_2 1278309.KB907101_gene562 3.44e-174 495.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1XKGD@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_18292_1 351348.Maqu_3380 5.18e-142 415.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,464XU@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0286 Type I restriction-modification system methyltransferase subunit hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_12016_4 1122185.N792_05260 6.62e-24 97.1 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1X3H9@135614|Xanthomonadales 135614|Xanthomonadales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_150_1 1288826.MSNKSG1_00081 7.07e-91 283.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,465I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M (Lipo)protein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_150_2 1288826.MSNKSG1_00076 9.25e-70 211.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,468BF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 k141_19691_1 1049564.TevJSym_ag00880 5.44e-166 481.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1JAJ9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Fumarate reductase flavoprotein C-term aprA - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_8535_2 1095769.CAHF01000011_gene2009 1.57e-85 261.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2VPF9@28216|Betaproteobacteria 28216|Betaproteobacteria S Short-chain dehydrogenase reductase (SDR) - - - - - - - - - - - - adh_short k141_5777_1 1279015.KB908460_gene2877 8.14e-68 226.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1Y3YN@135624|Aeromonadales 135624|Aeromonadales H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_2240_1 1288826.MSNKSG1_09623 1.62e-171 492.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_10645_1 1278309.KB907102_gene124 8.06e-107 328.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XHDT@135619|Oceanospirillales 135619|Oceanospirillales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_10645_2 1278309.KB907102_gene121 6.05e-43 140.0 2E5ME@1|root,330CB@2|Bacteria,1N8G6@1224|Proteobacteria,1SC9I@1236|Gammaproteobacteria,1XM6X@135619|Oceanospirillales 135619|Oceanospirillales S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k141_10645_3 1278309.KB907102_gene120 4.84e-150 422.0 COG3751@1|root,COG3751@2|Bacteria,1NAUK@1224|Proteobacteria,1S2G4@1236|Gammaproteobacteria,1XJF9@135619|Oceanospirillales 135619|Oceanospirillales O Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5 k141_10645_4 1278309.KB907102_gene119 1.12e-45 152.0 COG2755@1|root,COG2755@2|Bacteria,1RDVJ@1224|Proteobacteria,1T0DW@1236|Gammaproteobacteria,1XRQC@135619|Oceanospirillales 135619|Oceanospirillales E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 k141_17589_1 580332.Slit_0530 4.29e-59 206.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_21140_1 1278309.KB907109_gene3280 2.57e-89 268.0 2EBA5@1|root,335AP@2|Bacteria,1QMAV@1224|Proteobacteria,1SEZT@1236|Gammaproteobacteria,1XMC8@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_21140_2 1278309.KB907109_gene3281 1.72e-54 181.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XII2@135619|Oceanospirillales 135619|Oceanospirillales H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_12719_1 1049564.TevJSym_af00270 1.11e-17 78.2 2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1841) - - - - - - - - - - - - DUF1841 k141_12719_3 472759.Nhal_2721 3.38e-52 172.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1WWJ1@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_16334_1 1479237.JMLY01000001_gene3656 1.51e-134 414.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_17788_1 1232683.ADIMK_0773 4e-99 313.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,469HX@72275|Alteromonadaceae 1236|Gammaproteobacteria S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_17788_2 1232683.ADIMK_0772 3.99e-32 120.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RNNH@1236|Gammaproteobacteria,4684Y@72275|Alteromonadaceae 1236|Gammaproteobacteria I Carboxylesterase family - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 k141_354_1 396588.Tgr7_2449 6.91e-78 247.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - PLDc_2 k141_21289_1 1122201.AUAZ01000038_gene1140 3.48e-22 94.4 COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,1RXX8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Alginate_exp k141_21289_2 1278309.KB907099_gene2640 1e-306 840.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI8Y@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_15686_2 1131553.JIBI01000056_gene162 1.88e-08 55.5 COG3767@1|root,COG3767@2|Bacteria,1PW5I@1224|Proteobacteria,2WBQU@28216|Betaproteobacteria,373MA@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_3167_2 272134.KB731324_gene6476 6.8e-13 67.0 2EA0N@1|root,33462@2|Bacteria,1GEKK@1117|Cyanobacteria,1HFYJ@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_3823_1 396588.Tgr7_2900 3.16e-124 401.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_19836_1 252305.OB2597_05735 9.95e-10 59.3 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,2PCZ9@252301|Oceanicola 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_19836_2 371731.Rsw2DRAFT_0670 2.88e-32 119.0 COG0586@1|root,COG0586@2|Bacteria,1Q68Z@1224|Proteobacteria,2UA40@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_9360_1 864702.OsccyDRAFT_5021 3.48e-09 59.7 COG1225@1|root,COG1225@2|Bacteria,1G66E@1117|Cyanobacteria,1HAHN@1150|Oscillatoriales 1117|Cyanobacteria O PFAM AhpC TSA family - - - - - - - - - - - - AhpC-TSA k141_8078_1 1278309.KB907104_gene819 3.42e-110 333.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1XJ12@135619|Oceanospirillales 135619|Oceanospirillales S Type VI secretion - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_12211_1 870967.VIS19158_15464 1.83e-90 294.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSCN@135623|Vibrionales 135623|Vibrionales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_20601_1 713586.KB900536_gene37 4.43e-68 236.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria 1224|Proteobacteria L double-strand break repair protein AddB addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_12905_1 1174504.AJTN02000012_gene3902 2.83e-38 142.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 k141_10819_4 10224.XP_006820728.1 4.33e-10 61.6 28KT9@1|root,2QT9F@2759|Eukaryota,39CC5@33154|Opisthokonta,3BBMC@33208|Metazoa,3D08F@33213|Bilateria 33208|Metazoa S PiggyBac transposable PGBD5 - - - - - - - - - - - DDE_Tnp_1_7 k141_6574_1 493475.GARC_2751 1.37e-21 100.0 COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,46D8D@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg,SBP_bac_3 k141_6574_2 1226994.AMZB01000116_gene2508 1.34e-17 76.3 2EI8B@1|root,33BZN@2|Bacteria,1NGJZ@1224|Proteobacteria,1SGEM@1236|Gammaproteobacteria,1YGXW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Protein of unknown function (DUF2835) VV12640 - - - - - - - - - - - DUF2835 k141_6574_3 765913.ThidrDRAFT_1862 3.48e-68 219.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria,1WX76@135613|Chromatiales 135613|Chromatiales E lysine 2,3-aminomutase - - - - - - - - - - - - - k141_15687_1 1288826.MSNKSG1_04866 9.74e-82 247.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,4650F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002 QueF,QueF_N k141_3168_1 314285.KT71_09502 3.39e-94 286.0 COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,1J9DV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase sqr - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_16335_2 1453501.JELR01000002_gene345 6.01e-10 61.2 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,46BMC@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_14262_1 1163617.SCD_n02039 1.64e-188 557.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria 28216|Betaproteobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_8703_1 207954.MED92_10469 3.38e-144 416.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1XHN5@135619|Oceanospirillales 135619|Oceanospirillales S Iron-sulfur cluster-binding domain pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_10078_1 323261.Noc_0082 3.7e-187 523.0 28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,1RR2S@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Sulfotransferase domain - - 2.8.2.1 ko:K01014 ko05204,map05204 - R01242 RC00007,RC00128 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 k141_3824_1 1121127.JAFA01000022_gene7762 3.9e-33 118.0 COG2608@1|root,COG2608@2|Bacteria,1RDCB@1224|Proteobacteria,2WHZS@28216|Betaproteobacteria,1KIRT@119060|Burkholderiaceae 28216|Betaproteobacteria P MerT mercuric transport protein - - - ko:K08363 - - - - ko00000,ko02000 1.A.72.1 - - MerT k141_9362_1 1123514.KB905899_gene1862 4.03e-58 192.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,45ZP5@72273|Thiotrichales 72273|Thiotrichales K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_8079_1 1278309.KB907099_gene2994 9.67e-73 221.0 COG0589@1|root,COG0589@2|Bacteria,1PHJB@1224|Proteobacteria,1RVW5@1236|Gammaproteobacteria,1XPQI@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - - - - - - - - - - Usp k141_8079_2 1278309.KB907099_gene2993 8.13e-91 278.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XICB@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_5194_1 1288826.MSNKSG1_16551 4.54e-100 303.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_5194_2 1288826.MSNKSG1_16556 5.22e-171 478.0 COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,1RMRT@1236|Gammaproteobacteria,466RS@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0778 Nitroreductase nfsA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016657,GO:0032553,GO:0034567,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.38 ko:K10678,ko:K19285 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 - R05706,R08014,R08017,R08042 RC00126,RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_5194_3 1288826.MSNKSG1_16561 7.58e-244 671.0 28HJP@1|root,2Z7UT@2|Bacteria,1MWM4@1224|Proteobacteria,1RQNG@1236|Gammaproteobacteria,465UV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2955) - - - - - - - - - - - - DUF2955,FUSC_2 k141_5194_4 1288826.MSNKSG1_16566 5.66e-62 199.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,4660V@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1566 Multidrug resistance efflux pump yiaV - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_16336_1 377629.TERTU_1671 1.97e-54 177.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,2PPX7@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_16336_2 1279017.AQYJ01000026_gene60 7.91e-15 72.4 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria 1236|Gammaproteobacteria U biopolymer transport protein - - - - - - - - - - - - ExbD k141_12212_1 580332.Slit_0452 2.28e-97 299.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria 28216|Betaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_12212_2 236097.ADG881_3022 3.18e-08 54.7 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,1XHYJ@135619|Oceanospirillales 135619|Oceanospirillales S Bile acid sodium symporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_3170_1 743974.MBO_03062 3.88e-36 133.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,3NJDM@468|Moraxellaceae 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_3170_2 626887.J057_14500 1.46e-43 146.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,466Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_20603_1 396588.Tgr7_0222 6.85e-46 161.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_1036_1 1288826.MSNKSG1_16061 4.93e-204 573.0 COG4590@1|root,COG4590@2|Bacteria,1MW7Q@1224|Proteobacteria,1S6QR@1236|Gammaproteobacteria,46BWI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - - k141_10820_1 697282.Mettu_3355 2.66e-210 596.0 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1S0WH@1236|Gammaproteobacteria,1XE0V@135618|Methylococcales 135618|Methylococcales O AAA ATPase central domain protein - - - - - - - - - - - - AAA k141_19838_1 1380358.JADJ01000007_gene3058 1.74e-14 74.7 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XIJ4@135619|Oceanospirillales 135619|Oceanospirillales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_19838_2 1121920.AUAU01000008_gene1567 5.01e-20 90.5 COG0739@1|root,COG0739@2|Bacteria,3Y5PX@57723|Acidobacteria 57723|Acidobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_357_1 1227739.Hsw_4076 2.42e-69 219.0 COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,47P8G@768503|Cytophagia 976|Bacteroidetes S Putative cyclase - - - - - - - - - - - - Cyclase k141_2429_1 1366046.HIMB11_01685 1.96e-189 538.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,3ZFZF@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_21292_1 983545.Glaag_1277 4.28e-43 157.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,464PS@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleQ - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_14264_1 396588.Tgr7_0499 3.53e-87 276.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_8704_1 754476.Q7A_2971 4.87e-76 253.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,45ZUT@72273|Thiotrichales 72273|Thiotrichales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_7317_1 1288826.MSNKSG1_05161 6.23e-194 546.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,463YH@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iE2348C_1286.E2348C_4372,iJN746.PP_4187 Pyr_redox_2,Pyr_redox_dim k141_7317_2 1288826.MSNKSG1_05166 9.29e-271 742.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,46480@72275|Alteromonadaceae 1236|Gammaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 ko:K01903,ko:K14067 ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00346,M00374,M00620 R00405,R01256,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k141_7317_4 1288826.MSNKSG1_05176 1.91e-293 800.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,464FH@72275|Alteromonadaceae 1236|Gammaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_21987_2 159087.Daro_1572 4.23e-64 203.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VHQ0@28216|Betaproteobacteria,2KY79@206389|Rhodocyclales 206389|Rhodocyclales K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_1775_1 1449351.RISW2_11925 8.52e-83 251.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2TUXV@28211|Alphaproteobacteria,4KKZK@93682|Roseivivax 28211|Alphaproteobacteria S ErfK YbiS YcfS YnhG family protein - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - YkuD k141_19229_1 1552758.NC00_15840 1.5e-33 123.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1X631@135614|Xanthomonadales 135614|Xanthomonadales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_14981_1 1079460.ATTQ01000004_gene1882 9.27e-28 120.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - Guanylate_cyc k141_21311_1 1278309.KB907100_gene2291 5.82e-123 358.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XHRC@135619|Oceanospirillales 135619|Oceanospirillales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_5224_1 566466.NOR53_2680 2.5e-117 359.0 COG1538@1|root,COG1538@2|Bacteria,1MUHM@1224|Proteobacteria,1RNNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU outer membrane efflux protein - - - - - - - - - - - - OEP k141_19859_1 1149133.ppKF707_4649 2.19e-11 65.5 COG1638@1|root,COG1638@2|Bacteria,1PER4@1224|Proteobacteria,1RSR0@1236|Gammaproteobacteria 1236|Gammaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_19859_2 467661.RKLH11_3714 2.33e-05 46.2 COG3090@1|root,COG3090@2|Bacteria,1R4WJ@1224|Proteobacteria,2U2ZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system small permease component uehB - - - - - - - - - - - DctQ k141_20615_2 717774.Marme_3843 2.92e-96 292.0 COG0697@1|root,COG0697@2|Bacteria,1P3V0@1224|Proteobacteria,1S25I@1236|Gammaproteobacteria,1XNDW@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_15717_1 1278309.KB907105_gene1544 1.97e-69 224.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1XM0P@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_13596_1 1288826.MSNKSG1_01883 6.49e-98 292.0 COG1262@1|root,COG1262@2|Bacteria,1PDSD@1224|Proteobacteria,1S4ZV@1236|Gammaproteobacteria,46CJV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase k141_13596_2 1288826.MSNKSG1_01868 0.0 985.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM k141_7329_1 1278309.KB907103_gene1068 8.52e-230 659.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHFD@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_7329_2 1278309.KB907103_gene1067 4.45e-29 104.0 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,1XMBA@135619|Oceanospirillales 135619|Oceanospirillales P Cytochrome oxidase maturation protein - - - - - - - - - - - - FixS k141_7329_3 1278309.KB907103_gene1066 6.16e-123 354.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1XJ7Q@135619|Oceanospirillales 135619|Oceanospirillales S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_7329_4 1278309.KB907103_gene1065 2.8e-310 848.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1XHZ4@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM k141_7329_5 1042375.AFPL01000040_gene2777 5.06e-148 421.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,466GX@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases anr - - ko:K01420 - - - - ko00000,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding k141_7329_6 207954.MED92_03772 7.56e-107 310.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,1XJA2@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k141_7329_7 1278309.KB907103_gene1060 6.01e-195 543.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XI17@135619|Oceanospirillales 135619|Oceanospirillales L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k141_7329_8 1278309.KB907103_gene1058 3.32e-127 364.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1XIHG@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_7329_9 1278309.KB907103_gene1057 4.27e-133 386.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,1XJUT@135619|Oceanospirillales 135619|Oceanospirillales S Na -dependent transporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_17804_1 1278309.KB907108_gene1588 1.92e-189 550.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XITB@135619|Oceanospirillales 135619|Oceanospirillales S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_8807_3 1278309.KB907099_gene2751 1.84e-62 191.0 COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,1XK3W@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_gamma k141_8807_4 1278309.KB907099_gene2752 8.41e-31 110.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,1XKWI@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta k141_11648_1 1002340.AFCF01000054_gene1896 1.22e-146 423.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,34EKI@302485|Phaeobacter 28211|Alphaproteobacteria P Ammonium Transporter Family amt_1 - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_10977_1 1219080.VEZ01S_05_01400 6.63e-31 119.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1XSG0@135623|Vibrionales 135623|Vibrionales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_10977_2 519989.ECTPHS_04044 4.69e-18 76.6 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1WYVD@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_6703_1 90814.KL370891_gene748 8.19e-46 166.0 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,1TA9R@1236|Gammaproteobacteria,462QW@72273|Thiotrichales 72273|Thiotrichales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_D23 k141_6703_2 1278309.KB907105_gene1387 1.87e-182 544.0 COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,1RRTY@1236|Gammaproteobacteria,1XIWC@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase M50 - - - ko:K16922 - - - - ko00000,ko01002 - - - HlyD_3,HlyD_D23 k141_6703_3 207954.MED92_17284 3.94e-183 541.0 COG0653@1|root,COG0653@2|Bacteria,1MX0P@1224|Proteobacteria,1S0FZ@1236|Gammaproteobacteria,1XIP3@135619|Oceanospirillales 135619|Oceanospirillales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - - - - - - - - - - SecA_DEAD,SecA_PP_bind k141_6703_4 945543.VIBR0546_11652 5.46e-06 55.1 COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1Y2J0@135623|Vibrionales 135623|Vibrionales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_6703_5 1278309.KB907105_gene1390 1.98e-249 689.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1XIJX@135619|Oceanospirillales 135619|Oceanospirillales E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - ACT_6,HAD k141_6703_6 5664.LmjF.30.2990 7.75e-31 129.0 2CWSK@1|root,2RV57@2759|Eukaryota,3XSMY@5653|Kinetoplastida 5653|Kinetoplastida S Protein of unknown function (DUF2817) - - - - - - - - - - - - DUF2817 k141_6703_7 314271.RB2654_08552 0.000672 45.1 2D1C5@1|root,32TAD@2|Bacteria,1N23F@1224|Proteobacteria,2U94F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Ceramidase - - - - - - - - - - - - Ceramidase k141_19983_1 264730.PSPPH_4876 1.04e-60 194.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1Z53V@136849|Pseudomonas syringae group 1236|Gammaproteobacteria E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD k141_15862_1 349102.Rsph17025_1181 3.24e-15 75.1 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2TQNS@28211|Alphaproteobacteria,1FB9R@1060|Rhodobacter 28211|Alphaproteobacteria EG Belongs to the IlvD Edd family edd - 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_15862_2 1461693.ATO10_02440 1.48e-67 214.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U77K@28211|Alphaproteobacteria 28211|Alphaproteobacteria G 6-phosphogluconolactonase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_15862_3 314271.RB2654_01815 6.73e-68 220.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_18605_1 1101195.Meth11DRAFT_0171 1.73e-15 73.2 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2W80N@28216|Betaproteobacteria,2KN7N@206350|Nitrosomonadales 206350|Nitrosomonadales S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY k141_17217_1 631362.Thi970DRAFT_01208 1.97e-27 108.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1WW5K@135613|Chromatiales 135613|Chromatiales E phosphoserine phosphatase SerB - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - ACT_6,HAD k141_17217_2 765911.Thivi_2275 3.19e-62 200.0 COG0590@1|root,COG2154@1|root,COG0590@2|Bacteria,COG2154@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1WXZ8@135613|Chromatiales 135613|Chromatiales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam k141_17217_3 713586.KB900536_gene2319 1.1e-27 108.0 COG3703@1|root,COG3703@2|Bacteria 2|Bacteria P gamma-glutamylcyclotransferase activity ykqA - - - - - - - - - - - AIG2_2,GGACT k141_17217_4 745411.B3C1_13928 1.16e-111 340.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1J571@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k141_5407_1 367336.OM2255_08220 1.02e-99 321.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_21446_1 323261.Noc_2102 6.1e-23 97.4 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1WWVF@135613|Chromatiales 135613|Chromatiales S Competence protein - - - - - - - - - - - - Pribosyltran k141_21446_2 555778.Hneap_0927 5.06e-15 75.1 2E1SU@1|root,32X2N@2|Bacteria,1N4HW@1224|Proteobacteria,1SAEX@1236|Gammaproteobacteria,1X167@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_21446_3 493475.GARC_5373 1.37e-54 182.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,46540@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_12421_2 511.JT27_17645 7.28e-28 112.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,3T2B9@506|Alcaligenaceae 28216|Betaproteobacteria F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH k141_13096_2 396588.Tgr7_2644 1.24e-46 159.0 COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_3332_1 1283300.ATXB01000001_gene490 1.99e-113 345.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XE33@135618|Methylococcales 135618|Methylococcales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_11005_1 391615.ABSJ01000009_gene1577 2.27e-16 76.6 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1J4IP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_11005_2 228410.NE1166 1.68e-119 360.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,372IM@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 k141_1260_1 1123247.AUIJ01000004_gene1018 1.78e-59 197.0 COG0224@1|root,COG0224@2|Bacteria,1N4GR@1224|Proteobacteria,2U4XH@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0224 F0F1-type ATP synthase, gamma subunit atpG_1 - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_13790_1 371731.Rsw2DRAFT_0042 2.57e-58 187.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,1FBNI@1060|Rhodobacter 28211|Alphaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_18631_1 438753.AZC_2051 2.36e-73 230.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,3F1I4@335928|Xanthobacteraceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_14382_1 1278309.KB907099_gene2675 0.0 1171.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,1XIC3@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the GcvT family soxA - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_3964_1 1278309.KB907100_gene2252 4.8e-22 94.7 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1XHM9@135619|Oceanospirillales 135619|Oceanospirillales G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_3964_2 1122599.AUGR01000002_gene3414 2.58e-193 551.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XI5B@135619|Oceanospirillales 135619|Oceanospirillales V MATE efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_1918_1 1500893.JQNB01000001_gene935 5.14e-80 250.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1X3BM@135614|Xanthomonadales 135614|Xanthomonadales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_5422_1 1122197.ATWI01000009_gene1817 1.75e-92 280.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,464JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0451 Nucleoside-diphosphate-sugar epimerases capI - 5.1.3.25,5.1.3.6 ko:K08679,ko:K17947 ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130 - R01385,R10279 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_7498_1 870187.Thini_1905 5.88e-147 436.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,45ZSF@72273|Thiotrichales 72273|Thiotrichales E arginine decarboxylase speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N k141_7498_2 765911.Thivi_3471 1.32e-134 389.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1WX1H@135613|Chromatiales 135613|Chromatiales E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth k141_7498_3 1149133.ppKF707_5866 4.82e-07 53.9 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria,1YGHW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_7498_4 62928.azo1315 5.09e-117 343.0 COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,2VJX0@28216|Betaproteobacteria,2KXZK@206389|Rhodocyclales 206389|Rhodocyclales S Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 k141_8824_2 1225785.CM001983_gene3011 5.64e-51 172.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,2JBTR@204037|Dickeya 1236|Gammaproteobacteria F Belongs to the CarA family carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k141_13097_1 883081.HMPREF9698_01308 1.84e-30 117.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,27FXT@186828|Carnobacteriaceae 91061|Bacilli M UDP binding domain ugd GO:0003674,GO:0003824,GO:0003979,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_13097_2 1283300.ATXB01000001_gene760 9.76e-48 156.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1S4VI@1236|Gammaproteobacteria,1XF76@135618|Methylococcales 135618|Methylococcales O PFAM Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_6057_1 1242864.D187_005937 3.23e-49 171.0 COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Phosphonate ABC transporter, periplasmic - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_22120_2 395493.BegalDRAFT_1766 1.78e-52 167.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,4613Z@72273|Thiotrichales 72273|Thiotrichales K regulatory protein, arsR - - - - - - - - - - - - HTH_5 k141_6718_1 367336.OM2255_10411 1.45e-136 413.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_17991_1 765911.Thivi_2751 1.13e-14 72.8 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1WX71@135613|Chromatiales 135613|Chromatiales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_17991_2 290398.Csal_0568 7.16e-67 216.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1XJNR@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 k141_17991_3 1469245.JFBG01000023_gene1250 3.55e-99 298.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1WX0N@135613|Chromatiales 135613|Chromatiales I Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k141_17991_4 297246.lpp1676 1.63e-85 256.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1JD7Q@118969|Legionellales 118969|Legionellales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF k141_17991_5 264730.PSPPH_3838 5e-48 160.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1Z52N@136849|Pseudomonas syringae group 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_8233_1 765914.ThisiDRAFT_1413 5.15e-58 186.0 COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1WY69@135613|Chromatiales 135613|Chromatiales NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_17226_1 225937.HP15_3652 1.94e-99 296.0 COG0542@1|root,COG0542@2|Bacteria,1PWAB@1224|Proteobacteria,1RRT2@1236|Gammaproteobacteria,4656B@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0542 ATPases with chaperone activity, ATP-binding subunit - - - - - - - - - - - - AAA_2,ClpB_D2-small k141_17226_2 1288826.MSNKSG1_14347 8.47e-225 620.0 COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,1RY6Z@1236|Gammaproteobacteria,465SH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates amiE - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_13791_1 909663.KI867151_gene3085 1.16e-23 101.0 COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WMCV@28221|Deltaproteobacteria,2MQYF@213462|Syntrophobacterales 28221|Deltaproteobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k141_13791_2 1121413.JMKT01000009_gene1894 1.75e-12 69.7 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2M82Q@213115|Desulfovibrionales 28221|Deltaproteobacteria T TIGRFAM Diguanylate cyclase - - - - - - - - - - - - GAF_2,GGDEF k141_12422_1 765910.MARPU_03210 1.34e-126 373.0 COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1WW5K@135613|Chromatiales 135613|Chromatiales E phosphoserine phosphatase SerB - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - ACT_6,HAD k141_5423_2 1177181.T9A_01100 2.93e-16 78.6 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1T1NU@1236|Gammaproteobacteria,1XRUE@135619|Oceanospirillales 135619|Oceanospirillales C Pyridine nucleotide-disulphide oxidoreductase rubB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0015046,GO:0016491,GO:0016730,GO:0016731,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_21460_1 582744.Msip34_0601 1e-41 147.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,2KMHV@206350|Nitrosomonadales 206350|Nitrosomonadales S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 k141_21460_2 1286106.MPL1_11663 2.93e-60 198.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales 72273|Thiotrichales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_22121_1 272624.lpg2341 3.77e-24 104.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1JCZQ@118969|Legionellales 118969|Legionellales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_17992_1 1278309.KB907107_gene1736 2.39e-116 345.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XIEK@135619|Oceanospirillales 135619|Oceanospirillales K Flagellar regulatory protein FleQ - - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_10267_1 1232683.ADIMK_2978 0.0 882.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,4660Y@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit hyuA - 3.5.2.14,6.4.1.6 ko:K01473,ko:K10855 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_14383_1 644107.SL1157_2950 1.85e-56 181.0 COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,4NA2Z@97050|Ruegeria 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal ctrA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02483,ko:K13584 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_14383_2 1231392.OCGS_2338 5.41e-31 111.0 2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1153) MA20_11245 - - - - - - - - - - - DUF1153 k141_1262_2 1250005.PHEL85_0727 2.98e-18 90.1 COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia,3VVN7@52959|Polaribacter 976|Bacteroidetes M Sulfatase - - - - - - - - - - - - Sulfatase k141_13098_1 765912.Thimo_1348 2.94e-122 373.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales 135613|Chromatiales M HAD-superfamily hydrolase, subfamily IIB - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_11006_1 187272.Mlg_0671 1.06e-163 479.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_17993_1 997884.HMPREF1068_01470 5.57e-11 65.1 COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,2FNAN@200643|Bacteroidia,4AMAS@815|Bacteroidaceae 976|Bacteroidetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_3965_1 1278309.KB907101_gene683 1.98e-182 514.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XIB1@135619|Oceanospirillales 135619|Oceanospirillales S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_4732_2 1208321.D104_14505 7.61e-144 414.0 COG0583@1|root,COG0583@2|Bacteria,1RKM8@1224|Proteobacteria,1SMWM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_1,LysR_substrate k141_13792_1 420324.KI911970_gene1564 4.45e-117 356.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_15128_1 1380394.JADL01000003_gene4757 1.56e-93 303.0 COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2TU9N@28211|Alphaproteobacteria,2JSM5@204441|Rhodospirillales 204441|Rhodospirillales S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_1921_1 395019.Bmul_2304 3.74e-67 207.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,1KCBP@119060|Burkholderiaceae 28216|Betaproteobacteria O Thioredoxin trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_20712_2 1282361.ABAC402_04735 2.34e-07 61.6 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,2KFQU@204458|Caulobacterales 204458|Caulobacterales MU type I secretion outer membrane protein, TolC family - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_8826_1 498211.CJA_0700 1.94e-79 241.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1FGMD@10|Cellvibrio 1236|Gammaproteobacteria J Ribosomal protein L4/L1 family rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_6059_1 1278309.KB907099_gene2777 5.27e-208 577.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XIAR@135619|Oceanospirillales 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_6719_1 1122201.AUAZ01000001_gene2402 4.88e-94 285.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1S2UM@1236|Gammaproteobacteria,46B71@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - ko:K18954 - - - - ko00000,ko03000 - - - Cupin_2,HTH_18 k141_11007_1 1454004.AW11_00061 6.7e-82 256.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria 28216|Betaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_11007_2 676032.FN3523_0947 1.4e-22 93.2 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,4606Q@72273|Thiotrichales 72273|Thiotrichales L Exodeoxyribonuclease III xth xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_13793_1 1179773.BN6_21530 1.31e-45 168.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_18806_1 1123400.KB904817_gene1533 2.59e-40 137.0 COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,1SEQ6@1236|Gammaproteobacteria,462KV@72273|Thiotrichales 72273|Thiotrichales S CbiX - - 4.99.1.4 ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R02864 RC01012 ko00000,ko00001,ko00002,ko01000 - - - CbiX k141_18806_2 631362.Thi970DRAFT_02925 7.92e-24 97.8 28HKZ@1|root,2Z7VP@2|Bacteria,1R4QW@1224|Proteobacteria,1RZQX@1236|Gammaproteobacteria,1WX0D@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF3050) - - - - - - - - - - - - DUF3050 k141_7656_1 305900.GV64_02490 1.17e-18 88.6 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,1XHPJ@135619|Oceanospirillales 135619|Oceanospirillales I phospholipid glycerol acyltransferase - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k141_7656_2 396588.Tgr7_0093 9.18e-89 273.0 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RY1Q@1236|Gammaproteobacteria,1WX7C@135613|Chromatiales 135613|Chromatiales L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_9026_1 1122201.AUAZ01000036_gene1229 1.97e-49 159.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1SA21@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Ferredoxin - - - ko:K04755 - - - - ko00000 - - - Fer2 k141_9026_2 1122201.AUAZ01000036_gene1228 7.65e-98 300.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,4645M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Reductase C-terminal alkT - 1.18.1.1,1.18.1.3 ko:K00529,ko:K21738 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C k141_14562_1 767434.Fraau_1747 1.92e-59 192.0 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1X4MF@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.2.1.109 ko:K08964 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_14562_2 1127695.HMPREF9163_02229 9.3e-13 74.3 COG1409@1|root,COG3540@1|root,COG1409@2|Bacteria,COG3540@2|Bacteria,1TS7Q@1239|Firmicutes 1239|Firmicutes P Tat pathway signal sequence domain protein - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N k141_682_2 257313.BP0372 5.01e-11 62.4 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,3T2VE@506|Alcaligenaceae 28216|Betaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_19498_1 258594.RPA1565 8.14e-59 191.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2TSIQ@28211|Alphaproteobacteria,3JR6D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_19498_2 504832.OCAR_4896 2.06e-56 190.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria,3JVAV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein domain - - - - - - - - - - - - Peripla_BP_6 k141_14563_1 395493.BegalDRAFT_2926 4.12e-30 114.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,4631W@72273|Thiotrichales 72273|Thiotrichales NT Type IV pili signal transduction protein PilI - - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_9027_1 1342301.JASD01000008_gene2567 0.00029 40.8 2ADCK@1|root,31328@2|Bacteria,1PRN2@1224|Proteobacteria,2V3WV@28211|Alphaproteobacteria,3ZY5J@60136|Sulfitobacter 28211|Alphaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - - - - - - - - - - CcmD k141_9027_2 1415756.JQMY01000001_gene2798 2.14e-69 215.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,2PDYP@252301|Oceanicola 28211|Alphaproteobacteria CO COG0526 Thiol-disulfide isomerase and thioredoxins ccmG GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin k141_9675_1 1288826.MSNKSG1_01698 1.24e-47 157.0 COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,467AT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1279 Lysine efflux permease argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - iPC815.YPO0918 LysE k141_9675_2 1288826.MSNKSG1_01703 2.07e-87 256.0 COG4321@1|root,COG4321@2|Bacteria,1MZP2@1224|Proteobacteria,1S865@1236|Gammaproteobacteria,468CX@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - - - - - - - - - - RHH_4 k141_15233_1 1245471.PCA10_05540 4.19e-17 79.3 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1YE09@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G HAD-hyrolase-like gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 HAD_2 k141_15233_3 1278309.KB907107_gene1646 1.15e-108 329.0 2E4X4@1|root,32ZR3@2|Bacteria,1N9TG@1224|Proteobacteria,1SDVJ@1236|Gammaproteobacteria,1XMUX@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3530) - - - - - - - - - - - - DUF3530 k141_683_1 1158760.AQXP01000049_gene673 1.16e-20 87.0 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_20071_1 402626.Rpic_2660 2.24e-12 67.4 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,1K1P1@119060|Burkholderiaceae 28216|Betaproteobacteria P Periplasmic binding protein btuF - - ko:K02016,ko:K06858 ko02010,map02010 M00240,M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13,3.A.1.14 - - Peripla_BP_2 k141_19499_1 314271.RB2654_04149 1.04e-73 233.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom k141_20854_1 870187.Thini_0770 1.16e-64 210.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,45ZQU@72273|Thiotrichales 72273|Thiotrichales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_6828_1 568706.BN118_1764 1.62e-68 218.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2VJCQ@28216|Betaproteobacteria,3T5UU@506|Alcaligenaceae 28216|Betaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_6828_2 1158762.KB898037_gene2296 1.98e-13 70.9 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1WYZ4@135613|Chromatiales 135613|Chromatiales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_18807_1 414684.RC1_3430 6.52e-19 82.8 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,2JSRE@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_18807_2 1502852.FG94_00778 7.26e-34 139.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4760P@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9 k141_17398_1 395493.BegalDRAFT_3330 9.84e-75 228.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,460MP@72273|Thiotrichales 72273|Thiotrichales J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_17398_2 1120963.KB894510_gene2763 1.53e-20 83.2 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,2Q336@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_17398_3 1121035.AUCH01000004_gene287 2.99e-61 190.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales 206389|Rhodocyclales J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k141_6257_1 1255043.TVNIR_2630 5.06e-05 45.4 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NTP binding protein (Contains STAS domain) yrbB - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 k141_6257_2 686340.Metal_0049 4.94e-38 137.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1XG1I@135618|Methylococcales 135618|Methylococcales Q MlaC protein - - - - - - - - - - - - MlaC k141_6257_3 1265490.JHVY01000005_gene1528 6.08e-27 104.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents periplasmic component mlaD GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_9028_1 1121286.AUMT01000005_gene3163 5.4e-08 56.2 COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,1HYIK@117743|Flavobacteriia,3ZPH1@59732|Chryseobacterium 976|Bacteroidetes M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41,Tricorn_C1 k141_7657_1 159087.Daro_1187 9.2e-108 312.0 COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,2KX1Q@206389|Rhodocyclales 206389|Rhodocyclales S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_7657_3 1288826.MSNKSG1_02088 1.13e-84 249.0 COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,1S5VV@1236|Gammaproteobacteria 1236|Gammaproteobacteria G mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 k141_2053_1 717231.Flexsi_0440 2.57e-112 337.0 COG3547@1|root,COG3547@2|Bacteria 2|Bacteria L Transposase (IS116 IS110 IS902 family) - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_20855_1 1407650.BAUB01000003_gene901 9.2e-15 73.2 COG3954@1|root,COG3954@2|Bacteria,1GBJ0@1117|Cyanobacteria,1GZPB@1129|Synechococcus 1117|Cyanobacteria C Phosphoribulokinase prkB - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK k141_20855_2 765911.Thivi_4352 4.54e-12 67.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,1WWYY@135613|Chromatiales 135613|Chromatiales S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_17399_1 388401.RB2150_03993 1.97e-28 107.0 2CF2J@1|root,32S52@2|Bacteria,1MZP1@1224|Proteobacteria,2UBUJ@28211|Alphaproteobacteria,3ZHUH@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S TfoX C-terminal domain - - - - - - - - - - - - TfoX_C k141_9676_2 876044.IMCC3088_2093 4.11e-12 65.9 COG2010@1|root,COG3245@1|root,COG2010@2|Bacteria,COG3245@2|Bacteria,1QVK1@1224|Proteobacteria,1RYEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrome_CBB3 k141_685_1 1239962.C943_00843 3.61e-18 78.6 COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 k141_685_2 1408473.JHXO01000002_gene3986 3.01e-31 117.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT k141_9029_1 1396858.Q666_14440 2.02e-35 123.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_9029_2 396588.Tgr7_2247 1.21e-38 134.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales 135613|Chromatiales S Belongs to the WrbA family - - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_6829_2 1231391.AMZF01000003_gene3107 7.94e-13 69.7 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,3T29P@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF1732) yicC - - - - - - - - - - - DUF1732,YicC_N k141_2054_1 666509.RCA23_c26470 8.36e-87 268.0 COG1574@1|root,COG1574@2|Bacteria,1QVE6@1224|Proteobacteria,2TSU6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Acyclic terpene utilisation family protein AtuA - - - - - - - - - - - - AtuA k141_20856_2 525373.HMPREF0766_12574 1.66e-10 60.5 COG1431@1|root,COG1431@2|Bacteria,4NH01@976|Bacteroidetes,1IUPQ@117747|Sphingobacteriia 976|Bacteroidetes J PFAM Stem cell self-renewal protein Piwi - - - - - - - - - - - - SIR2_2 k141_20073_1 998674.ATTE01000001_gene511 1.46e-64 209.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4601Y@72273|Thiotrichales 72273|Thiotrichales F Belongs to the GARS family purD - 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N,SAICAR_synt k141_20073_2 1123511.KB905845_gene2826 6.71e-08 58.5 COG1368@1|root,COG1368@2|Bacteria,1U3T0@1239|Firmicutes,4H3X2@909932|Negativicutes 909932|Negativicutes M Sulfatase - - - - - - - - - - - - Sulfatase k141_9703_7 1288826.MSNKSG1_08083 0.0 2276.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,464IX@72275|Alteromonadaceae 1236|Gammaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_9703_8 225937.HP15_2255 2.16e-167 479.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,465BD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_14629_1 243233.MCA0607 3.82e-119 357.0 COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria,1XEJK@135618|Methylococcales 135618|Methylococcales G alpha beta alpha domain I pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_15268_1 493475.GARC_4265 3.75e-20 97.4 COG2931@1|root,COG2982@1|root,COG4733@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG4733@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS k141_11792_1 875328.JDM601_3702 1.82e-07 56.6 COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,2335C@1762|Mycobacteriaceae 201174|Actinobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - - - - - - - - - - adh_short k141_11792_2 1224318.DT73_19620 1.63e-06 50.1 COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,1S3R3@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19,TPR_2,TPR_8 k141_20904_2 405948.SACE_2538 6.59e-35 130.0 COG2391@1|root,COG2391@2|Bacteria,2I94E@201174|Actinobacteria 201174|Actinobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_4084_1 1278309.KB907100_gene2175 1.37e-140 407.0 COG2199@1|root,COG3706@2|Bacteria,1N7HG@1224|Proteobacteria,1S2NP@1236|Gammaproteobacteria,1XJSG@135619|Oceanospirillales 135619|Oceanospirillales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_4084_2 1278309.KB907100_gene2174 2.78e-124 372.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K21021 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - CHASE8,EAL,GAF,GAF_2,GGDEF,HAMP,PAS_3,PAS_9 k141_20113_1 1249627.D779_4049 2.59e-48 159.0 COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,1SAZP@1236|Gammaproteobacteria,1X2B1@135613|Chromatiales 135613|Chromatiales P Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin k141_14631_1 1288826.MSNKSG1_08528 6.6e-61 196.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,46573@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 ATP-grasp k141_14632_1 566466.NOR53_2748 2.24e-36 135.0 COG3568@1|root,COG3568@2|Bacteria,1RJZP@1224|Proteobacteria,1TH72@1236|Gammaproteobacteria,1JABN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos k141_20114_1 857087.Metme_4024 1.68e-18 94.4 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XEBN@135618|Methylococcales 135618|Methylococcales NU COG3170 Tfp pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - k141_15270_1 857087.Metme_0114 2e-125 366.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XESU@135618|Methylococcales 135618|Methylococcales S associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_9704_2 877455.Metbo_0953 8.64e-23 104.0 COG0530@1|root,arCOG02881@2157|Archaea,2XVHN@28890|Euryarchaeota,23PNH@183925|Methanobacteria 183925|Methanobacteria P K -dependent Na Ca - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_20905_1 396588.Tgr7_2153 7.61e-92 284.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_20905_2 697282.Mettu_0032 1.34e-55 185.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1XF2F@135618|Methylococcales 135618|Methylococcales L Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_20905_3 1163617.SCD_n01595 1.94e-26 103.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria 28216|Betaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789,ko:K14742 - - - - ko00000,ko01000,ko03009,ko03016 - - - Acetyltransf_1,Peptidase_M22 k141_6875_1 85643.Tmz1t_1303 1.47e-44 154.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VP2F@28216|Betaproteobacteria 28216|Betaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_6875_2 644801.Psest_1585 3.91e-177 507.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,1Z442@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Peptidase dimerisation domain - - 3.5.1.32 ko:K01451 ko00360,map00360 - R01424 RC00096,RC00162 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 k141_6875_3 85643.Tmz1t_1301 2.18e-95 291.0 COG0583@1|root,COG0583@2|Bacteria,1P2I1@1224|Proteobacteria,2VR8C@28216|Betaproteobacteria,2KXS4@206389|Rhodocyclales 206389|Rhodocyclales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_4086_2 754476.Q7A_1328 3.37e-64 221.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,45ZYC@72273|Thiotrichales 72273|Thiotrichales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_20115_1 1278309.KB907102_gene126 3.4e-54 169.0 COG1018@1|root,COG1018@2|Bacteria,1N6XY@1224|Proteobacteria,1SC8M@1236|Gammaproteobacteria,1XMIR@135619|Oceanospirillales 135619|Oceanospirillales C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K11107 - - - - ko00000 - - - Fer2 k141_11795_1 626887.J057_19030 1.13e-44 163.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,464FC@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_15271_1 1288494.EBAPG3_25850 3.44e-34 137.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,372EE@32003|Nitrosomonadales 28216|Betaproteobacteria T Double sensory domain of two-component sensor kinase - - - - - - - - - - - - 7TMR-DISM_7TM,EAL,GGDEF,PAS,PAS_4,dCache_3 k141_4087_1 153721.MYP_4329 6.64e-76 247.0 COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia 976|Bacteroidetes L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_6876_1 367336.OM2255_03610 4.09e-84 258.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_6876_2 571166.KI421509_gene540 2.81e-07 52.4 298HD@1|root,2ZVNE@2|Bacteria,1RDBR@1224|Proteobacteria,2U79Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Component of SufBCD complex - - - - - - - - - - - - - k141_9705_2 580332.Slit_0790 2.07e-59 185.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,44VVQ@713636|Nitrosomonadales 28216|Betaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_14634_2 580332.Slit_1714 4.28e-110 317.0 COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,2W0BB@28216|Betaproteobacteria 28216|Betaproteobacteria C Adenosine-5'-phosphosulfate reductase beta subunit - - 1.8.99.2 ko:K00395 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - APS-reductase_C,Fer4 k141_14634_3 396588.Tgr7_0352 1.73e-78 242.0 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_4089_2 314287.GB2207_06318 7.04e-16 72.4 2EJUZ@1|root,33DJM@2|Bacteria,1NIYD@1224|Proteobacteria,1SGV4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_6330_1 1288826.MSNKSG1_10088 3.14e-175 510.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,4642Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide hypF GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_14728_1 497321.C664_14718 2.77e-60 191.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,2KWA8@206389|Rhodocyclales 206389|Rhodocyclales L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_8427_1 290397.Adeh_3378 4.89e-103 313.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2WKS4@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_18891_1 765912.Thimo_1839 1.25e-137 400.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_4933_2 665950.HMPREF1025_01290 0.000386 46.6 COG1310@1|root,COG1310@2|Bacteria 2|Bacteria S proteolysis - - - - - - - - - - - - Prok-JAB k141_21028_1 1288826.MSNKSG1_01118 2.84e-115 335.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_21028_2 1288826.MSNKSG1_01123 3.67e-173 483.0 COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RZYE@1236|Gammaproteobacteria 1236|Gammaproteobacteria I hemolysin - - - - - - - - - - - - Acetyltransf_5 k141_21028_3 1288826.MSNKSG1_01128 1.29e-168 471.0 COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria,466I3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain rstA - - ko:K07661 ko02020,map02020 M00446 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_21028_4 1288826.MSNKSG1_01133 5.31e-210 590.0 COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,1RMF5@1236|Gammaproteobacteria,46743@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase rstB - 2.7.13.3 ko:K02484,ko:K07639 ko02020,map02020 M00446 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_20303_1 1232683.ADIMK_3124 1.48e-147 449.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain virA - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_7,Response_reg k141_20303_2 1123487.KB892839_gene145 8.24e-96 287.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria,2KVPH@206389|Rhodocyclales 206389|Rhodocyclales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_20303_3 1232683.ADIMK_3122 7.88e-291 804.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,464TD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcSMS35_1347.EcSMS35_4486 PGI k141_17469_1 1121035.AUCH01000020_gene2647 2.03e-35 134.0 COG5581@1|root,COG5581@2|Bacteria,1RBFR@1224|Proteobacteria,2VQWE@28216|Betaproteobacteria,2M037@206389|Rhodocyclales 206389|Rhodocyclales M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - - - - - - - - - - PilZ,YcgR k141_16093_1 1288826.MSNKSG1_01098 2.39e-119 347.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,464XR@72275|Alteromonadaceae 1236|Gammaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) tas GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - - - - - - - - - - Aldo_ket_red k141_16093_2 1288826.MSNKSG1_01093 6.59e-294 802.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,465YK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_16093_3 1288826.MSNKSG1_01088 2.67e-128 365.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,466ER@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_16093_4 1288826.MSNKSG1_01083 4.77e-129 373.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,464UA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_15428_1 1158292.JPOE01000005_gene1120 2.52e-79 249.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1KJ18@119065|unclassified Burkholderiales 28216|Betaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_19586_1 1278309.KB907100_gene1809 3.45e-80 241.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XJ63@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k141_19586_2 1278309.KB907100_gene1810 1.09e-41 147.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1XHF6@135619|Oceanospirillales 135619|Oceanospirillales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_3558_1 1479237.JMLY01000001_gene3654 1.35e-74 228.0 COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,4641M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1989) IV02_09290 - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_13331_1 1278309.KB907107_gene1720 1.42e-15 72.0 COG2882@1|root,COG2882@2|Bacteria,1RHFM@1224|Proteobacteria,1S76M@1236|Gammaproteobacteria,1XMAE@135619|Oceanospirillales 135619|Oceanospirillales NOU Flagellar FliJ protein fliJ - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_13331_2 1278309.KB907107_gene1721 4.26e-88 271.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XHGZ@135619|Oceanospirillales 135619|Oceanospirillales NU Involved in type III protein export during flagellum assembly fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_16799_1 1288826.MSNKSG1_02213 1.14e-240 669.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_5689_1 297246.lpp1351 5.26e-37 125.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1JEY0@118969|Legionellales 118969|Legionellales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_5689_2 523791.Kkor_1188 6.54e-102 301.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1XHUP@135619|Oceanospirillales 135619|Oceanospirillales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_14738_1 1278309.KB907099_gene2738 4.81e-81 247.0 COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1XHUT@135619|Oceanospirillales 135619|Oceanospirillales K LuxR family luxR - - - - - - - - - - - GerE,Response_reg k141_14738_2 1278309.KB907099_gene2737 0.0 954.0 COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,1XH4U@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_13348_2 1049564.TevJSym_au00520 5.64e-22 89.4 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1J6V4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_13348_3 765911.Thivi_3977 6.79e-24 97.4 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1WXHT@135613|Chromatiales 135613|Chromatiales I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD k141_4249_2 314275.MADE_1007510 1.96e-29 115.0 COG0110@1|root,COG0110@2|Bacteria,1RDQE@1224|Proteobacteria,1S3RJ@1236|Gammaproteobacteria,466XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (Isoleucine patch superfamily) - - - - - - - - - - - - Hexapep,Hexapep_2 k141_4249_3 326427.Cagg_0813 3.28e-06 48.9 COG0318@1|root,COG0318@2|Bacteria,2G7N1@200795|Chloroflexi,37718@32061|Chloroflexia 32061|Chloroflexia IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_15444_1 1288826.MSNKSG1_07083 2.16e-104 303.0 COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,466RV@72275|Alteromonadaceae 1236|Gammaproteobacteria M lipocalin blc GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_15444_2 1288826.MSNKSG1_07088 2.07e-185 517.0 COG0564@1|root,COG0564@2|Bacteria,1R4IN@1224|Proteobacteria,1S0WR@1236|Gammaproteobacteria,466SG@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0564 Pseudouridylate synthases, 23S RNA-specific - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 k141_15444_3 1288826.MSNKSG1_07093 5.55e-243 667.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,464JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0451 Nucleoside-diphosphate-sugar epimerases capI - 5.1.3.25,5.1.3.6 ko:K08679,ko:K17947 ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130 - R01385,R10279 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_15444_4 1288826.MSNKSG1_07098 1.63e-22 92.4 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,467AR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_19591_1 1278309.KB907101_gene322 3.02e-128 376.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XIMN@135619|Oceanospirillales 135619|Oceanospirillales MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_19591_2 1278309.KB907101_gene321 6.11e-137 392.0 COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZMR@1236|Gammaproteobacteria,1XJJC@135619|Oceanospirillales 135619|Oceanospirillales ET belongs to the bacterial solute-binding protein 3 family - - - - - - - - - - - - SBP_bac_3 k141_19591_3 1278309.KB907101_gene320 0.0 1419.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_21664_3 1430440.MGMSRv2_2047 3.44e-11 62.8 COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria 1224|Proteobacteria P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_21664_5 1123501.KB902277_gene976 5.35e-50 165.0 COG3791@1|root,COG3791@2|Bacteria,1RD31@1224|Proteobacteria,2U7QB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating, GFA - - - - - - - - - - - - GFA k141_21664_7 396588.Tgr7_1675 2.22e-22 100.0 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,SBP_bac_3 k141_21047_1 2340.JV46_08890 1.21e-66 212.0 COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1J914@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_14035_1 1178482.BJB45_04995 1.29e-75 240.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XI3H@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_65_1 765911.Thivi_1973 2.5e-24 102.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales 135613|Chromatiales U sulphate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_65_2 572477.Alvin_1981 5.34e-59 201.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXQ0@135613|Chromatiales 135613|Chromatiales P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C k141_3572_1 1415778.JQMM01000001_gene469 3.48e-142 422.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14,6.4.1.6 ko:K01474,ko:K10854 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_7049_1 686340.Metal_2523 2.22e-19 85.9 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1XDWI@135618|Methylococcales 135618|Methylococcales V pfam abc - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_7049_2 713586.KB900536_gene2461 1.08e-43 158.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_11272_1 1288826.MSNKSG1_05988 0.0 968.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,46605@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein pctC - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_11272_2 1288826.MSNKSG1_05993 2.97e-201 566.0 COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,4648Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_20327_1 1502770.JQMG01000001_gene219 4.02e-37 130.0 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KMQH@206350|Nitrosomonadales 206350|Nitrosomonadales F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ - - - - - - - - - - - NUDIX k141_16103_1 1278309.KB907108_gene1614 4.55e-55 181.0 COG1073@1|root,COG1073@2|Bacteria,1QUQB@1224|Proteobacteria 1224|Proteobacteria S alpha beta - - - - - - - - - - - - Esterase_phd k141_16103_2 1278309.KB907108_gene1613 1.42e-65 201.0 2EPGT@1|root,33H3D@2|Bacteria,1NK25@1224|Proteobacteria,1SHYF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16103_3 1278309.KB907108_gene1612 1.37e-188 526.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XI5N@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_16103_4 1122197.ATWI01000012_gene579 8.74e-260 713.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_16103_5 1278309.KB907108_gene1610 1.84e-177 497.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1XHYQ@135619|Oceanospirillales 135619|Oceanospirillales S Serine hydrolase involved in the detoxification of formaldehyde - - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase k141_10541_1 1288826.MSNKSG1_11328 1.58e-12 65.5 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,4678G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yibQ - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_10541_2 1288826.MSNKSG1_11333 3.66e-177 494.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,464M7@72275|Alteromonadaceae 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - ko:K01663,ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481 His_biosynth k141_10541_3 1288826.MSNKSG1_11338 1.23e-169 474.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,464AA@72275|Alteromonadaceae 1236|Gammaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_10541_4 1288826.MSNKSG1_11343 6.97e-155 434.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,465J2@72275|Alteromonadaceae 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_10541_5 1288826.MSNKSG1_11348 4.57e-139 393.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,4643N@72275|Alteromonadaceae 1236|Gammaproteobacteria E belongs to the histidinol- phosphatase family hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iUMNK88_1353.UMNK88_2570 Hydrolase_like,IGPD,PNK3P k141_10541_6 1288826.MSNKSG1_11353 1.4e-107 310.0 COG2867@1|root,COG2867@2|Bacteria,1RI5E@1224|Proteobacteria,1S8NQ@1236|Gammaproteobacteria,46B39@72275|Alteromonadaceae 1236|Gammaproteobacteria I negative regulation of translational initiation - - - - - - - - - - - - Polyketide_cyc2 k141_10541_7 1288826.MSNKSG1_11358 4.9e-173 503.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_17481_1 1026882.MAMP_01160 4.86e-38 133.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,4612Y@72273|Thiotrichales 72273|Thiotrichales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k141_11945_1 379731.PST_3905 3.52e-62 207.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1Z1J9@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria JKL Belongs to the DEAD box helicase family dbpA GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_9829_1 323850.Shew_0922 2.06e-08 57.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QB5T@267890|Shewanellaceae 1236|Gammaproteobacteria NT PFAM histidine kinase, HAMP region domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal,TarH k141_9829_2 765914.ThisiDRAFT_1920 3.23e-59 187.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales 135613|Chromatiales U general secretion pathway protein G - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_7775_1 105559.Nwat_0114 5.05e-29 126.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_3573_1 1288826.MSNKSG1_14327 1.79e-154 460.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,465IY@72275|Alteromonadaceae 1236|Gammaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_12633_1 399739.Pmen_3436 1.94e-62 207.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1YFC8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M BCCT, betaine/carnitine/choline family transporter - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_12633_2 400668.Mmwyl1_2474 1.88e-128 379.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI11@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_10542_1 90813.JQMT01000001_gene753 1.96e-94 284.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_15445_1 589865.DaAHT2_0051 1.61e-24 106.0 COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Response_reg k141_776_1 754476.Q7A_1564 3.6e-101 315.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,4607W@72273|Thiotrichales 72273|Thiotrichales M sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_776_2 317025.Tcr_1795 1.6e-16 77.4 COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,461KZ@72273|Thiotrichales 72273|Thiotrichales S HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP k141_6347_1 1288826.MSNKSG1_10663 1.2e-225 625.0 COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Alkane 1-monooxygenase alkB2 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase k141_6347_2 1288826.MSNKSG1_10668 1.48e-137 391.0 COG1802@1|root,COG1802@2|Bacteria,1RIE7@1224|Proteobacteria,1S6K0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - FCD,GntR k141_2162_1 497321.C664_08763 1.75e-90 277.0 2EFDX@1|root,3396Q@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_220_1 1049564.TevJSym_an00380 5.33e-57 191.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C k141_9263_1 1278309.KB907103_gene1017 1.35e-32 115.0 COG2030@1|root,COG2030@2|Bacteria,1RCCM@1224|Proteobacteria,1S39P@1236|Gammaproteobacteria,1XJN4@135619|Oceanospirillales 135619|Oceanospirillales I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas k141_9263_2 1278309.KB907103_gene1016 2.8e-234 646.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1XHSU@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_9263_3 1278309.KB907103_gene1015 2.19e-97 286.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XHZB@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_6472_1 1288826.MSNKSG1_02654 0.0 1098.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,464S9@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind k141_6472_2 1288826.MSNKSG1_02659 7.81e-64 195.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,46792@72275|Alteromonadaceae 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_6472_3 1288826.MSNKSG1_02664 1.81e-81 241.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,467A4@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance VL23_01195 - - - - - - - - - - - MerR_1 k141_6472_4 270374.MELB17_17483 7.75e-29 103.0 2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SEIJ@1236|Gammaproteobacteria,4697E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_6472_6 1288826.MSNKSG1_02674 5.44e-140 396.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,46APW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1282) yohC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - - - - - - - - - - DUF1282 k141_6472_7 1288826.MSNKSG1_02679 1.15e-204 567.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,4663Y@72275|Alteromonadaceae 1236|Gammaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA k141_6472_8 1288826.MSNKSG1_02684 1.2e-64 197.0 COG3125@1|root,COG3125@2|Bacteria,1RHE5@1224|Proteobacteria,1S6KQ@1236|Gammaproteobacteria,468UD@72275|Alteromonadaceae 1236|Gammaproteobacteria C cytochrome o ubiquinol oxidase cyoD - - ko:K02300 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - - COX4_pro k141_6472_9 1288826.MSNKSG1_02689 1.99e-142 402.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,465YZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 cyoC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0019646,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070069,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902494,GO:1902600 - ko:K02299 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - iPC815.YPO3166 COX3 k141_6472_10 1288826.MSNKSG1_02694 0.0 1342.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,465FP@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the heme-copper respiratory oxidase family cyoB - 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 k141_6472_11 1288826.MSNKSG1_02699 3.57e-199 553.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,464J0@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 cyoA - 1.10.3.10 ko:K02297 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX2,COX_ARM k141_3742_1 523791.Kkor_2259 2.16e-110 323.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales 135619|Oceanospirillales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_1641_1 1123399.AQVE01000019_gene1610 3.94e-80 245.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales 72273|Thiotrichales P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_12104_1 2340.JV46_08900 1.73e-58 187.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1J6WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_12104_2 930169.B5T_01505 5.07e-79 249.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XHGP@135619|Oceanospirillales 135619|Oceanospirillales S ATPase components of ABC transporters with duplicated ATPase domains - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_17676_1 1134912.AJTV01000026_gene2695 3.09e-08 58.2 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,36XDN@31993|Methylocystaceae 28211|Alphaproteobacteria E Shikimate dehydrogenase substrate binding domain aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_17676_2 1121403.AUCV01000002_gene602 2.56e-208 587.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria 1224|Proteobacteria G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k141_17676_3 1121403.AUCV01000002_gene603 4.07e-40 141.0 COG3090@1|root,COG3090@2|Bacteria,1RH2H@1224|Proteobacteria 1224|Proteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - - - - - - - - - - DctQ k141_16239_1 1208321.D104_13460 8.81e-169 482.0 COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria,1XIQ9@135619|Oceanospirillales 135619|Oceanospirillales L Transposase - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k141_19737_1 1124780.ANNU01000017_gene1913 2.19e-164 474.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) pccB - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_9264_1 644107.SL1157_0639 8.77e-102 321.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,4NABB@97050|Ruegeria 28211|Alphaproteobacteria C E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_9950_1 1387312.BAUS01000004_gene1420 2.26e-10 68.2 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,2KMI1@206350|Nitrosomonadales 206350|Nitrosomonadales M PFAM AsmA family - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 k141_10721_1 296591.Bpro_3847 9.43e-51 169.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,4AB9G@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM HNH endonuclease - - - - - - - - - - - - HNH_5 k141_21203_1 1123401.JHYQ01000002_gene2800 7.45e-96 294.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,461QY@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_8608_1 1385935.N836_33920 0.000128 51.6 COG2905@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1H9V4@1150|Oscillatoriales 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - CBS,EAL,GGDEF,PAS_4,PAS_9 k141_20492_1 717774.Marme_3855 6.4e-124 362.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1XHPK@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_11416_1 1289387.AUKW01000011_gene776 1.32e-35 137.0 COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria 201174|Actinobacteria O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_11416_2 1288826.MSNKSG1_10093 1.93e-10 57.0 2DCC8@1|root,2ZDND@2|Bacteria 2|Bacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - - - - - - - - - - HypA k141_19093_1 1122169.AREN01000016_gene1289 3.34e-22 95.5 COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,1SHXB@1236|Gammaproteobacteria,1JCKU@118969|Legionellales 118969|Legionellales K TipAS antibiotic-recognition domain - - - - - - - - - - - - MerR_1,TipAS k141_7941_1 396588.Tgr7_0181 9.49e-82 248.0 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria,1WXHF@135613|Chromatiales 135613|Chromatiales Q PFAM isochorismatase hydrolase - - - - - - - - - - - - Isochorismatase k141_9265_1 1269813.ATUL01000001_gene1139 2.22e-20 88.2 COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1WZFF@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 k141_14188_1 1049564.TevJSym_ba00210 3.22e-168 499.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1J51H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_3744_1 395964.KE386496_gene1902 1.11e-30 123.0 28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2U822@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_10722_1 1124780.ANNU01000021_gene2970 4.65e-37 132.0 COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_18372_2 550540.Fbal_0186 3.27e-12 65.5 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - iJN746.PP_0104 COX1 k141_922_1 1318628.MARLIPOL_04740 2.31e-221 614.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,464CS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_922_2 1318628.MARLIPOL_04735 6.72e-238 689.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_12106_1 222984.JNCS01000001_gene2236 0.000414 48.9 COG0840@1|root,arCOG02322@1|root,arCOG02320@2157|Archaea,arCOG02322@2157|Archaea,2XTG0@28890|Euryarchaeota,23SU9@183963|Halobacteria 183963|Halobacteria N Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_11417_1 519989.ECTPHS_05586 8.49e-76 239.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 k141_9951_1 1298593.TOL_2140 3.05e-10 61.2 COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria,1S52T@1236|Gammaproteobacteria,1XK9J@135619|Oceanospirillales 135619|Oceanospirillales M Tol-Pal system TolA - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_947_1 400668.Mmwyl1_2481 1.83e-37 131.0 COG1802@1|root,COG1802@2|Bacteria,1P6WQ@1224|Proteobacteria,1SYFS@1236|Gammaproteobacteria,1XQAF@135619|Oceanospirillales 135619|Oceanospirillales K FCD - - - - - - - - - - - - FCD,GntR k141_947_2 400668.Mmwyl1_2480 2.15e-120 347.0 28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,1RS5H@1236|Gammaproteobacteria,1XPE6@135619|Oceanospirillales 135619|Oceanospirillales S Amino acid synthesis - - - - - - - - - - - - AA_synth k141_947_3 717774.Marme_2436 1.97e-13 68.9 COG2267@1|root,COG2267@2|Bacteria,1MWT9@1224|Proteobacteria,1SYFR@1236|Gammaproteobacteria,1XPQ6@135619|Oceanospirillales 135619|Oceanospirillales I PFAM Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_4468_1 95619.PM1_0228990 4.21e-67 219.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_4468_2 396588.Tgr7_0002 1.07e-134 395.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1WWQF@135613|Chromatiales 135613|Chromatiales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_4468_3 187272.Mlg_0001 1.31e-221 625.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales 135613|Chromatiales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_4468_4 1437882.AZRU01000031_gene87 3.43e-23 94.4 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1YG8N@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_4468_5 556268.OFAG_02357 1.98e-24 94.7 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,474RM@75682|Oxalobacteraceae 28216|Betaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD - - ko:K08998 - - - - ko00000 - - - Haemolytic k141_4468_6 335283.Neut_2154 3.6e-10 64.7 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,371S5@32003|Nitrosomonadales 28216|Betaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_6481_1 1288826.MSNKSG1_13967 5.74e-253 696.0 COG0624@1|root,COG0624@2|Bacteria,1MW2W@1224|Proteobacteria,1S1T9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_6481_2 1288826.MSNKSG1_13972 4.49e-149 420.0 COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,1S35C@1236|Gammaproteobacteria,46DH3@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - - - - - - - - - - - CoA_trans k141_6481_3 1288826.MSNKSG1_13977 1.88e-158 445.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,1RNXB@1236|Gammaproteobacteria,4644U@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit atoD - 2.8.3.5,2.8.3.8,2.8.3.9 ko:K01028,ko:K01034 ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R00410,R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_6481_4 1288826.MSNKSG1_13982 0.0 891.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,466B4@72275|Alteromonadaceae 1236|Gammaproteobacteria E Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 k141_6481_5 1288826.MSNKSG1_13987 4.35e-208 576.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_6481_6 1288826.MSNKSG1_13992 1.8e-67 204.0 COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,4687U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - ko:K09700 - - - - ko00000 - - - - k141_20518_1 1123368.AUIS01000012_gene758 1.63e-61 209.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,2NCR4@225057|Acidithiobacillales 225057|Acidithiobacillales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_20518_2 76114.ebA4847 2.14e-44 158.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales 206389|Rhodocyclales C COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_18386_1 314278.NB231_00655 1.87e-47 171.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_12120_1 1278309.KB907100_gene2055 1.74e-44 149.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XKTT@135619|Oceanospirillales 135619|Oceanospirillales S Integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k141_12120_2 743720.Psefu_0304 1.22e-34 121.0 COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0235 family yggU - - ko:K09131 - - - - ko00000 - - - DUF167 k141_12120_3 1278309.KB907100_gene2057 7e-266 729.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales 135619|Oceanospirillales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_12120_4 1278309.KB907100_gene2058 9.98e-138 389.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,1XJBT@135619|Oceanospirillales 135619|Oceanospirillales Q Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW k141_12120_5 1278309.KB907100_gene2059 4.38e-78 236.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1XKW6@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4426) - - - - - - - - - - - - DUF4426 k141_12120_6 1278309.KB907100_gene2060 1.76e-128 366.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1XJ9C@135619|Oceanospirillales 135619|Oceanospirillales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_12120_7 1278309.KB907100_gene2061 1.39e-209 585.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XH6E@135619|Oceanospirillales 135619|Oceanospirillales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM k141_2303_1 1396858.Q666_07055 1.71e-71 217.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4679A@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH k141_244_1 1123237.Salmuc_02294 7.67e-22 93.2 COG0583@1|root,COG0583@2|Bacteria,1Q6E2@1224|Proteobacteria,2U671@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_244_2 644076.SCH4B_3688 3.61e-134 388.0 COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria,4NAR4@97050|Ruegeria 28211|Alphaproteobacteria G Periplasmic binding protein domain chvE GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K02058,ko:K10546 ko02010,map02010 M00216,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.5 - - Peripla_BP_4 k141_10731_1 1165841.SULAR_03053 1.25e-89 269.0 COG2191@1|root,COG2191@2|Bacteria,1NX7R@1224|Proteobacteria,430UJ@68525|delta/epsilon subdivisions 1224|Proteobacteria C FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - - - - - - - - - - FmdE k141_7952_1 1288826.MSNKSG1_01033 2.03e-165 479.0 COG2936@1|root,COG2936@2|Bacteria,1R4GM@1224|Proteobacteria,1RRE7@1236|Gammaproteobacteria,46AX5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase S15 - - - - - - - - - - - - Peptidase_S15 k141_7952_2 1288826.MSNKSG1_01038 0.0 891.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,4653M@72275|Alteromonadaceae 1236|Gammaproteobacteria T ATPase related to phosphate starvation-inducible protein PhoH phoH2 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_7952_3 1288826.MSNKSG1_01043 2.66e-110 317.0 COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,467S1@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_7952_4 1288826.MSNKSG1_01048 1.3e-169 474.0 COG2867@1|root,COG2867@2|Bacteria,1QU02@1224|Proteobacteria,1T3BK@1236|Gammaproteobacteria,46D9S@72275|Alteromonadaceae 1236|Gammaproteobacteria I START domain - - - - - - - - - - - - START k141_7952_5 1288826.MSNKSG1_01053 2.54e-243 668.0 COG3250@1|root,COG3250@2|Bacteria,1R87I@1224|Proteobacteria,1RZ7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Protein of unknown function (DUF2804) - - - - - - - - - - - - DUF2804 k141_7952_6 1288826.MSNKSG1_01058 8.7e-51 160.0 COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,46887@72275|Alteromonadaceae 1236|Gammaproteobacteria D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell minE GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007049,GO:0007346,GO:0008150,GO:0009987,GO:0010564,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032465,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051726,GO:0061640,GO:0065007,GO:0071840,GO:0071944,GO:0090529,GO:1901891,GO:1902410,GO:1902412,GO:1903047,GO:1903436 - ko:K03608 - - - - ko00000,ko03036,ko04812 - - - MinE k141_7952_7 1288826.MSNKSG1_01063 2.38e-184 513.0 COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,1RNJ0@1236|Gammaproteobacteria,464CZ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the ParA family minD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007059,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051782,GO:0060187,GO:0065007,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_7952_8 1288826.MSNKSG1_01068 4.4e-166 466.0 COG0850@1|root,COG0850@2|Bacteria,1RHVN@1224|Proteobacteria,1S6K8@1236|Gammaproteobacteria,466YD@72275|Alteromonadaceae 1236|Gammaproteobacteria D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007346,GO:0008150,GO:0009987,GO:0010564,GO:0032465,GO:0032954,GO:0032955,GO:0042802,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051726,GO:0060187,GO:0065007,GO:1901891,GO:1902412,GO:1903436 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C,MinC_N k141_7952_9 1288826.MSNKSG1_01073 3.3e-89 261.0 2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,4682V@72275|Alteromonadaceae 1236|Gammaproteobacteria S HopJ type III effector protein hopJ - - - - - - - - - - - HopJ k141_7952_10 1288826.MSNKSG1_01078 5.48e-63 192.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,467TP@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_17390 - - ko:K09948 - - - - ko00000 - - - DUF1244 k141_7952_11 1288826.MSNKSG1_01083 1.94e-132 382.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,464UA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_19108_1 1408439.JHXW01000003_gene1576 3.03e-69 230.0 COG1132@1|root,COG1132@2|Bacteria,379H4@32066|Fusobacteria 32066|Fusobacteria V K11085 ATP-binding cassette, subfamily B, bacterial MsbA - - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_948_1 1502851.FG93_05546 8.8e-20 93.6 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,3JUBJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_11554_1 351348.Maqu_3545 4.88e-75 233.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4675T@72275|Alteromonadaceae 1236|Gammaproteobacteria P molybdenum ABC transporter, periplasmic modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_11554_2 1123517.JOMR01000001_gene1822 3.1e-08 53.9 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_2478_1 1278309.KB907100_gene2182 0.0 1033.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XI8B@135619|Oceanospirillales 135619|Oceanospirillales M protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA k141_2478_2 1278309.KB907100_gene2183 3.85e-235 649.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1XI99@135619|Oceanospirillales 135619|Oceanospirillales L glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_2478_3 1278309.KB907100_gene2184 2.34e-53 167.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1XKI4@135619|Oceanospirillales 135619|Oceanospirillales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic k141_7368_1 672.VV93_v1c09280 7.36e-19 92.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTM0@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,CHASE3,HBM,MCPsignal k141_3863_1 1538295.JY96_13145 3.8e-09 63.5 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,1KJPM@119065|unclassified Burkholderiales 28216|Betaproteobacteria NU Neisseria PilC beta-propeller domain pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_4607_1 686340.Metal_0588 2.92e-51 179.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1XFZ8@135618|Methylococcales 135618|Methylococcales J Amidase - - - - - - - - - - - - Amidase k141_4607_2 1122194.AUHU01000006_gene524 5.12e-10 60.1 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_10885_1 1123279.ATUS01000004_gene2955 2.08e-49 167.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RQZ9@1236|Gammaproteobacteria,1J9BQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H EH COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_10885_2 118173.KB235910_gene5102 1.2e-25 103.0 COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,1H7VM@1150|Oscillatoriales 1117|Cyanobacteria S TIGRFAM phenazine biosynthesis protein PhzF family - - 5.3.3.17 ko:K06998 ko00405,ko01130,ko02024,map00405,map01130,map02024 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - PhzC-PhzF k141_16401_2 396588.Tgr7_0997 1.76e-150 444.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_18508_1 1278309.KB907099_gene3054 1.8e-308 854.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1XI7N@135619|Oceanospirillales 135619|Oceanospirillales I Acetyl propionyl-CoA carboxylase, alpha subunit - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_18508_2 1278309.KB907099_gene3053 3.63e-194 541.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1XHUR@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_18508_3 1278309.KB907099_gene3052 1.98e-117 338.0 COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,1RZGS@1236|Gammaproteobacteria,1XJ1H@135619|Oceanospirillales 135619|Oceanospirillales S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD k141_18508_4 1278309.KB907099_gene3051 3.72e-174 499.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XHGR@135619|Oceanospirillales 135619|Oceanospirillales IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_15763_1 207954.MED92_14473 5.7e-74 236.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XHA7@135619|Oceanospirillales 135619|Oceanospirillales P Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_15763_2 1278309.KB907099_gene3044 9.56e-78 238.0 COG0590@1|root,COG0590@2|Bacteria,1N1ZH@1224|Proteobacteria,1S94B@1236|Gammaproteobacteria,1XKM6@135619|Oceanospirillales 135619|Oceanospirillales FJ Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - dCMP_cyt_deam_1 k141_6631_1 1158146.KB907128_gene1879 4.2e-21 93.6 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1WY25@135613|Chromatiales 135613|Chromatiales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 k141_8748_1 754477.Q7C_211 1.19e-90 281.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,460C8@72273|Thiotrichales 72273|Thiotrichales E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_17109_1 1122599.AUGR01000009_gene2426 3.31e-75 255.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XI6H@135619|Oceanospirillales 135619|Oceanospirillales E Dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_2479_1 351016.RAZWK3B_03025 2.17e-92 293.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,2P1J9@2433|Roseobacter 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_22021_1 1278309.KB907111_gene3367 2.3e-218 609.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1XHWT@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k141_22021_2 1278309.KB907111_gene3366 5.52e-73 220.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1XKZ9@135619|Oceanospirillales 135619|Oceanospirillales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_22021_3 1278309.KB907111_gene3365 1.32e-291 800.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1XHFX@135619|Oceanospirillales 135619|Oceanospirillales L ATPase related to the helicase subunit of the Holliday junction resolvase ycaJ - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_22021_4 1278309.KB907111_gene3364 2.37e-112 327.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1XKMW@135619|Oceanospirillales 135619|Oceanospirillales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA k141_22021_5 1178482.BJB45_04610 2e-18 84.3 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XH4C@135619|Oceanospirillales 135619|Oceanospirillales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_3229_1 323261.Noc_0825 1.01e-31 126.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_3229_2 556269.ACDQ01000013_gene629 2.39e-07 48.9 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VXVA@28216|Betaproteobacteria,4755X@75682|Oxalobacteraceae 28216|Betaproteobacteria H ThiS family thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_5958_1 754477.Q7C_1936 2.92e-35 125.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,4612G@72273|Thiotrichales 72273|Thiotrichales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_5958_2 395493.BegalDRAFT_3320 1.29e-41 150.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,46093@72273|Thiotrichales 72273|Thiotrichales LU TIGRFAM DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_17852_1 1278309.KB907101_gene702 1e-99 296.0 COG1158@1|root,COG1158@2|Bacteria,1PW77@1224|Proteobacteria,1RYAS@1236|Gammaproteobacteria,1XHRH@135619|Oceanospirillales 135619|Oceanospirillales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab k141_19896_2 1278309.KB907101_gene482 1.43e-160 456.0 COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,1RNIC@1236|Gammaproteobacteria,1XIIC@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator iciA - - ko:K05596 - - - - ko00000,ko03000,ko03036 - - - HTH_1,LysR_substrate k141_19896_3 870187.Thini_1596 2.5e-50 169.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,463S5@72273|Thiotrichales 72273|Thiotrichales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_19896_4 1535422.ND16A_1726 1.24e-135 391.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,2Q6JE@267889|Colwelliaceae 1236|Gammaproteobacteria S Ribosomal RNA large subunit methyltransferase D, RlmJ rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_19896_5 1278309.KB907101_gene478 7.99e-65 212.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1XH89@135619|Oceanospirillales 135619|Oceanospirillales G Dehydrogenase - - - - - - - - - - - - PQQ k141_11555_1 1123401.JHYQ01000013_gene630 4.56e-74 233.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales 72273|Thiotrichales S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_11555_2 631362.Thi970DRAFT_03647 0.00023 44.7 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1WWD0@135613|Chromatiales 135613|Chromatiales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_3864_1 1123247.AUIJ01000010_gene106 1.14e-101 320.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria 28211|Alphaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P k141_19273_1 316273.XCV1536 1.81e-126 379.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the DNA photolyase family phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_9407_1 857087.Metme_1621 5.04e-63 207.0 COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria,1XE0J@135618|Methylococcales 135618|Methylococcales C Nitrogenase cofactor biosynthesis protein NifB - - - ko:K02585 - - - - ko00000 - - - Nitro_FeMo-Co,Radical_SAM k141_9407_2 765913.ThidrDRAFT_3857 1.04e-44 146.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1WYVK@135613|Chromatiales 135613|Chromatiales C 4Fe-4S dicluster domain - - - - - - - - - - - - - k141_9407_4 395965.Msil_1764 6.59e-45 150.0 COG1393@1|root,COG1393@2|Bacteria,1MZ7Z@1224|Proteobacteria,2UCXA@28211|Alphaproteobacteria,3NB8I@45404|Beijerinckiaceae 28211|Alphaproteobacteria P ArsC family - - - - - - - - - - - - ArsC k141_9407_5 395493.BegalDRAFT_3082 2.39e-62 199.0 2BDS5@1|root,327FW@2|Bacteria,1N15E@1224|Proteobacteria,1RSEH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM NifQ nifQ - - ko:K15790 - - - - ko00000 - - - NifQ k141_9407_6 768671.ThimaDRAFT_2761 1.14e-112 335.0 COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,1WWMI@135613|Chromatiales 135613|Chromatiales O ADP-ribosyl-(Dinitrogen reductase) hydrolase - - 3.2.2.24 ko:K05521 - - - - ko00000,ko01000 - - - ADP_ribosyl_GH k141_9407_7 13035.Dacsa_1179 3.64e-06 47.8 COG0686@1|root,COG0686@2|Bacteria,1G11E@1117|Cyanobacteria 1117|Cyanobacteria C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_15028_1 1286631.X805_12320 1.49e-43 157.0 2DBFU@1|root,2Z90B@2|Bacteria,1PI0M@1224|Proteobacteria,2WGPR@28216|Betaproteobacteria,1KPCW@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 k141_15028_2 765910.MARPU_11665 4.82e-22 95.9 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_6632_1 143224.JQMD01000002_gene4268 9.37e-57 197.0 COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1HZB4@117743|Flavobacteriia 976|Bacteroidetes KT membrane - - - - - - - - - - - - DUF2339 k141_7370_1 313606.M23134_02497 1.18e-13 69.7 COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,47Q1Q@768503|Cytophagia 976|Bacteroidetes S haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E yjjG - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_7370_2 1124780.ANNU01000048_gene2118 4.99e-45 150.0 COG0640@1|root,COG0640@2|Bacteria,4NRN0@976|Bacteroidetes,47QVI@768503|Cytophagia 976|Bacteroidetes K arsR family arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 k141_10887_1 797302.Halru_0454 4.56e-08 57.0 COG2202@1|root,COG3413@1|root,arCOG02389@1|root,arCOG02276@2157|Archaea,arCOG02334@2157|Archaea,arCOG02389@2157|Archaea,2XVK2@28890|Euryarchaeota,23UC5@183963|Halobacteria 183963|Halobacteria T response regulator, receiver - - - - - - - - - - - - BAT,GAF_2,HTH_10,Response_reg k141_10887_2 246197.MXAN_2606 4.67e-10 62.8 COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,43BK1@68525|delta/epsilon subdivisions,2X6XW@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,Response_reg k141_5959_1 1278309.KB907107_gene1684 1.59e-103 318.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_17110_1 349521.HCH_01608 3.54e-44 153.0 COG4619@1|root,COG4619@2|Bacteria,1QTWV@1224|Proteobacteria,1S627@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam ABC transporter - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran k141_17110_2 870187.Thini_0225 2.3e-20 84.3 COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH k141_3865_1 999611.KI421504_gene2953 2.05e-69 231.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,28109@191028|Leisingera 28211|Alphaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_21345_1 1479237.JMLY01000001_gene3345 1.29e-97 285.0 COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,1S6EH@1236|Gammaproteobacteria,467ZF@72275|Alteromonadaceae 1236|Gammaproteobacteria S MOSC domain - - - - - - - - - - - - MOSC k141_21345_2 1288826.MSNKSG1_10493 7.08e-117 335.0 COG3613@1|root,COG3613@2|Bacteria,1N0AK@1224|Proteobacteria,1S88V@1236|Gammaproteobacteria,46BSC@72275|Alteromonadaceae 1236|Gammaproteobacteria F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr k141_12284_1 379731.PST_0054 2.85e-76 257.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNF@1236|Gammaproteobacteria,1Z0ZR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9 k141_12284_2 1123399.AQVE01000002_gene2260 3.44e-74 231.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S4J0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA k141_16402_1 1042377.AFPJ01000023_gene657 2.4e-75 263.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B k141_10888_1 1415778.JQMM01000001_gene1357 1.04e-37 140.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1J4RQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_5960_1 768671.ThimaDRAFT_0979 1.97e-36 129.0 COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_5960_2 56780.SYN_00534 4.91e-27 109.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2MQC9@213462|Syntrophobacterales 28221|Deltaproteobacteria S Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos k141_8139_2 756272.Plabr_0677 1.93e-121 360.0 COG1509@1|root,COG1509@2|Bacteria,2IYGS@203682|Planctomycetes 203682|Planctomycetes C lysine 2,3-aminomutase - - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Radical_SAM k141_8139_3 83406.HDN1F_18810 8.98e-60 218.0 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,1J70G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8139_4 765914.ThisiDRAFT_1000 1.57e-26 112.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales 135613|Chromatiales T PFAM EAL domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_9408_2 1286106.MPL1_09917 1.04e-90 281.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,45ZUG@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_10912_1 1150469.RSPPHO_01454 4.86e-14 70.9 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2TSAD@28211|Alphaproteobacteria,2JQ1D@204441|Rhodospirillales 204441|Rhodospirillales G Fructose-bisphosphate aldolase class-II cbbA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k141_10912_2 997346.HMPREF9374_0925 4.37e-81 248.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,27B18@186824|Thermoactinomycetaceae 91061|Bacilli G Ribulose-phosphate 3 epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_442_1 316067.Geob_2757 6.51e-59 194.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria 28221|Deltaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH k141_18519_1 1189612.A33Q_1366 2.01e-30 121.0 COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47KU0@768503|Cytophagia 976|Bacteroidetes E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 k141_3877_2 1123368.AUIS01000011_gene1190 2.54e-113 333.0 COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,1S29T@1236|Gammaproteobacteria,2NCSV@225057|Acidithiobacillales 225057|Acidithiobacillales V ABC-2 type transporter - - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane k141_3877_3 713586.KB900536_gene813 3.76e-82 256.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWG5@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K09695 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC_tran k141_22033_1 1278309.KB907099_gene2774 1.34e-121 359.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI11@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_19909_1 991905.SL003B_0063 3.14e-33 125.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TQYV@28211|Alphaproteobacteria,4BPJ8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_10157_1 273371.XP_003871353.1 1.45e-10 67.0 COG1723@1|root,KOG2861@2759|Eukaryota,38HM8@33154|Opisthokonta,3NUYI@4751|Fungi,3QMIX@4890|Ascomycota,3RRA6@4891|Saccharomycetes,47B2E@766764|Debaryomycetaceae 4751|Fungi S Uncharacterised ACR, YagE family COG1723 sif3 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005783,GO:0008150,GO:0008152,GO:0010467,GO:0012505,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140053 - - - - - - - - - - DUF155 k141_3247_2 1158756.AQXQ01000010_gene2192 1.55e-43 144.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_9427_1 236097.ADG881_2164 8.27e-89 271.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XHW9@135619|Oceanospirillales 135619|Oceanospirillales G belongs to the carbohydrate kinase PfkB family pfkB - 2.7.1.4,2.7.1.73 ko:K00847,ko:K00892 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00760,R00867,R01131,R01228,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_4631_1 272942.RCAP_rcc01146 2.48e-54 181.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,1FATI@1060|Rhodobacter 28211|Alphaproteobacteria C D-isomer specific 2-hydroxyacid dehydrogenase catalytic gyaR1 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 ko:K00015,ko:K00050,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R00717,R01388,R01392,R01739 RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_4631_2 1185766.DL1_18855 8.49e-69 212.0 COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,2TV1A@28211|Alphaproteobacteria,2XN08@285107|Thioclava 28211|Alphaproteobacteria F Thymidine kinase tdk - 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK k141_14320_1 1197130.BAFM01000008_gene1660 7.28e-75 233.0 297W1@1|root,2N5NZ@2157|Archaea,2XVHS@28890|Euryarchaeota,23UMZ@183963|Halobacteria 183963|Halobacteria S Domain of unknown function (DUF4396) - - - - - - - - - - - - DUF4396 k141_14320_2 56780.SYN_01247 1.08e-27 103.0 2DCXT@1|root,2ZFR8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_5309_1 247633.GP2143_02135 7.13e-14 70.5 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1J4QD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_5309_2 1232428.CAVO010000022_gene829 5.11e-16 79.3 COG0688@1|root,COG0688@2|Bacteria,1V3FQ@1239|Firmicutes,4H45T@909932|Negativicutes 909932|Negativicutes I Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_13112_1 1288826.MSNKSG1_10368 3.06e-76 233.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,1S3X9@1236|Gammaproteobacteria,467AY@72275|Alteromonadaceae 1236|Gammaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k141_21474_1 582744.Msip34_0322 2.38e-136 398.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KKX5@206350|Nitrosomonadales 206350|Nitrosomonadales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k141_21474_2 572265.HDEF_1845 4.2e-16 70.1 COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 k141_3975_1 1122164.JHWF01000008_gene1291 2.49e-27 103.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1JCRV@118969|Legionellales 118969|Legionellales F dCTP deaminase activity dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k141_3975_2 1500893.JQNB01000001_gene2208 1.6e-38 135.0 29RF5@1|root,30CHS@2|Bacteria,1QTMX@1224|Proteobacteria,1RXRG@1236|Gammaproteobacteria,1X6W2@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_1934_2 187272.Mlg_2264 1.03e-125 365.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1WW0T@135613|Chromatiales 135613|Chromatiales E PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_19371_1 1179778.PMM47T1_09771 4.22e-18 85.1 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_19995_1 272134.KB731324_gene6611 0.000527 49.7 COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales 1117|Cyanobacteria Q Domains in Na-Ca exchangers and integrin-beta4 - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - Calx-beta,DUF4347,HemolysinCabind,VCBS k141_19995_2 1121456.ATVA01000016_gene2034 7.59e-22 102.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales 28221|Deltaproteobacteria T SMART Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_2592_2 522306.CAP2UW1_3804 6.43e-07 53.5 COG2882@1|root,COG2882@2|Bacteria,1N21N@1224|Proteobacteria,2VU9D@28216|Betaproteobacteria 28216|Betaproteobacteria N Flagellar export protein FliJ fliJ - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_2592_3 765914.ThisiDRAFT_2475 9.05e-25 109.0 COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1WZU7@135613|Chromatiales 135613|Chromatiales N PFAM flagellar hook-length control - - - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_18649_1 1046724.KB889948_gene2188 4.74e-113 330.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1S0X9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Helix-hairpin-helix containing domain - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2 k141_17240_1 290400.Jann_0994 4.11e-115 344.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria U pilus assembly protein ATPase CpaF - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k141_13809_1 396588.Tgr7_2007 6.32e-93 285.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales 135613|Chromatiales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_7517_1 1168065.DOK_04492 7.56e-40 139.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1J53N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_12433_1 1297742.A176_03413 1.31e-07 52.8 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_12433_2 596151.DesfrDRAFT_2342 6.18e-108 318.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,2M8B0@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase uxs - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_9516_2 1278309.KB907100_gene2156 5.5e-148 433.0 2EKWC@1|root,33EJV@2|Bacteria,1NN1A@1224|Proteobacteria,1SJ8U@1236|Gammaproteobacteria,1XPX6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9516_3 1278309.KB907100_gene2157 5.48e-53 171.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XK6E@135619|Oceanospirillales 135619|Oceanospirillales L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_8251_1 301.JNHE01000001_gene343 6.3e-18 89.4 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1YDKA@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NU Neisseria PilC beta-propeller domain pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_15878_1 1278309.KB907099_gene2718 1.76e-67 213.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1XK16@135619|Oceanospirillales 135619|Oceanospirillales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_15878_2 1278309.KB907099_gene2717 1.05e-37 127.0 2E4CR@1|root,32Z86@2|Bacteria,1N9YH@1224|Proteobacteria,1SD46@1236|Gammaproteobacteria,1XMTY@135619|Oceanospirillales 135619|Oceanospirillales S NADH-dependant formate dehydrogenase delta subunit FdsD - - 1.17.1.9 ko:K00126 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - FdsD k141_15878_3 391735.Veis_1360 6.21e-71 224.0 COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,2VQK8@28216|Betaproteobacteria,4ADMB@80864|Comamonadaceae 28216|Betaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_14419_1 243233.MCA0602 0.000317 43.1 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XDXC@135618|Methylococcales 135618|Methylococcales O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_14419_2 765911.Thivi_1123 2.61e-45 157.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1WWTH@135613|Chromatiales 135613|Chromatiales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k141_15902_1 95619.PM1_0201865 4.31e-195 553.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_8848_1 643867.Ftrac_0067 3.35e-94 303.0 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_20006_2 1123393.KB891332_gene2814 1.76e-62 209.0 COG2206@1|root,COG2206@2|Bacteria,1MWDU@1224|Proteobacteria,2VIAF@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - HD_5 k141_12450_1 2340.JV46_11630 1.07e-33 118.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1J6BH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Endoribonuclease L-PSP tdcF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_12450_2 765914.ThisiDRAFT_1993 1.67e-208 603.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_18027_1 1122137.AQXF01000001_gene3151 6.82e-93 295.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_18671_1 768671.ThimaDRAFT_2995 9.72e-16 77.8 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,1X2DY@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_18671_2 1049564.TevJSym_ax00490 7.77e-57 197.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k141_3363_1 1337093.MBE-LCI_3313 7.46e-77 239.0 COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2TR13@28211|Alphaproteobacteria 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_3363_2 1337093.MBE-LCI_3314 2.22e-132 390.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_8263_1 565045.NOR51B_2347 4.8e-17 76.6 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1J73G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ccoH - - ko:K09926 - - - - ko00000 - - - FixH k141_8263_2 1255043.TVNIR_2181 2.27e-194 553.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_559_1 1288826.MSNKSG1_04601 1.05e-100 291.0 COG2050@1|root,COG2050@2|Bacteria,1RITB@1224|Proteobacteria,1S63Z@1236|Gammaproteobacteria,4679C@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT k141_559_2 1288826.MSNKSG1_04596 6.65e-112 321.0 COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,1S6I1@1236|Gammaproteobacteria,4680Z@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT k141_559_3 1288826.MSNKSG1_04591 1.38e-166 466.0 COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,466W1@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF599 k141_559_4 1288826.MSNKSG1_04586 8.46e-125 365.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,4660W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent protease, contains TPR repeats - - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_2,TPR_8 k141_4768_2 999141.GME_04327 1.17e-26 106.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XH6Q@135619|Oceanospirillales 135619|Oceanospirillales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_2607_1 1266998.ATUJ01000001_gene2552 1.89e-38 137.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,2PVWD@265|Paracoccus 28211|Alphaproteobacteria F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate deoD - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 k141_2607_2 1208323.B30_16863 7.57e-27 105.0 COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the binding-protein-dependent transport system permease family araH - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_3364_1 999541.bgla_1g38800 1.9e-51 177.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,1JZXE@119060|Burkholderiaceae 28216|Betaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_15903_1 1049564.TevJSym_aj00420 0.000711 41.6 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1J70E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the small heat shock protein (HSP20) family hspA - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_17259_1 998674.ATTE01000001_gene3239 4.65e-40 144.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S2MK@1236|Gammaproteobacteria,4613G@72273|Thiotrichales 72273|Thiotrichales F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k141_17259_2 1122599.AUGR01000002_gene3406 1.87e-133 389.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1SYY5@1236|Gammaproteobacteria,1XJ1I@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_5454_1 1123400.KB904769_gene2892 4.4e-105 315.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales 72273|Thiotrichales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_5454_2 1158762.KB898037_gene2369 0.000142 42.7 2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,1SHMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cbb3-type cytochrome oxidase component FixQ - - - - - - - - - - - - FixQ k141_5454_3 870187.Thini_3780 3.74e-137 392.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM cytochrome c oxidase, cbb3-type, subunit II - - - - - - - - - - - - FixO k141_5454_4 2340.JV46_27820 2.15e-43 154.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1J4J5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_1278_1 1190603.AJYD01000036_gene3818 3.41e-127 366.0 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,1RY9K@1236|Gammaproteobacteria,1Y0UI@135623|Vibrionales 135623|Vibrionales G Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_1278_2 391626.OAN307_c25760 3.23e-85 263.0 COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2U0PA@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10544 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - BPD_transp_2 k141_22155_1 1278309.KB907100_gene1876 8.35e-72 233.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XHM0@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_22155_2 1278309.KB907100_gene1877 7.29e-99 287.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1XJ6M@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_22155_3 1278309.KB907100_gene1878 1.39e-63 195.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1XKG3@135619|Oceanospirillales 135619|Oceanospirillales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_22155_4 1278309.KB907100_gene1879 3.53e-127 365.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1XK5V@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_22155_5 1278309.KB907100_gene1880 9.64e-85 261.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XI9W@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_18672_1 1278309.KB907102_gene101 3.9e-105 312.0 COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1S14J@1236|Gammaproteobacteria,1XHGS@135619|Oceanospirillales 135619|Oceanospirillales S Tim44 - - - - - - - - - - - - Tim44 k141_20007_1 519989.ECTPHS_13823 1.83e-76 241.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WXWZ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_560_1 399739.Pmen_4388 2.11e-67 210.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1YCUK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_18028_1 1131553.JIBI01000013_gene919 5.46e-97 298.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,372IM@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 k141_19386_1 3075.A0A087S9Z1 9.57e-99 301.0 COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,34GP0@3041|Chlorophyta 3041|Chlorophyta C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis cob - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_2608_1 768671.ThimaDRAFT_0841 6.59e-78 249.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C k141_8849_1 29486.NJ56_04885 2.73e-07 50.8 COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,1S2VE@1236|Gammaproteobacteria,41HKH@629|Yersinia 1236|Gammaproteobacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k141_8849_2 349521.HCH_04023 3.94e-84 259.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,1XNU4@135619|Oceanospirillales 135619|Oceanospirillales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_9536_2 1207063.P24_11185 2.11e-70 217.0 COG3090@1|root,COG3090@2|Bacteria,1MVKS@1224|Proteobacteria,2U08K@28211|Alphaproteobacteria,2JSXA@204441|Rhodospirillales 204441|Rhodospirillales G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_9536_3 1123355.JHYO01000050_gene787 1.51e-138 403.0 COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,2TV91@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component MA20_30160 - - - - - - - - - - - DctP k141_4769_1 1232437.KL662043_gene2228 5.39e-61 201.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MNE6@213118|Desulfobacterales 28221|Deltaproteobacteria S Sterol-sensing domain of SREBP cleavage-activation - - - - - - - - - - - - MMPL k141_12451_1 765910.MARPU_16665 7.03e-82 254.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales 135613|Chromatiales M Involved in formation and maintenance of cell shape - - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_6743_1 1122194.AUHU01000005_gene1043 3.42e-71 232.0 COG0642@1|root,COG0642@2|Bacteria,1MURQ@1224|Proteobacteria,1RP9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase fleS - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8 k141_6743_2 1049564.TevJSym_ac00780 2.55e-09 57.8 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4Q2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_20727_1 1185876.BN8_01275 1.14e-204 588.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_20727_2 102125.Xen7305DRAFT_00012600 3.07e-74 239.0 COG0837@1|root,COG0837@2|Bacteria,1G1TJ@1117|Cyanobacteria,3VJA8@52604|Pleurocapsales 1117|Cyanobacteria G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k141_18029_1 1278309.KB907100_gene1897 1.09e-105 312.0 COG0790@1|root,COG0790@2|Bacteria,1R5EJ@1224|Proteobacteria,1SM9R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_3366_1 492774.JQMB01000004_gene1889 6.11e-62 207.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,4BA9N@82115|Rhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 k141_8264_1 1288826.MSNKSG1_03916 1.32e-208 578.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria,466FW@72275|Alteromonadaceae 1236|Gammaproteobacteria O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family yagQ - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_8264_2 1288826.MSNKSG1_03911 2.96e-83 265.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_561_1 1441629.PCH70_02110 2.33e-14 67.4 2E5ME@1|root,330CB@2|Bacteria,1N8G6@1224|Proteobacteria,1SC9I@1236|Gammaproteobacteria,1Z85G@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Phosphate-starvation-inducible E IV02_05780 - - - - - - - - - - - PsiE k141_17260_1 935567.JAES01000008_gene1985 7.55e-20 84.0 COG1522@1|root,COG1522@2|Bacteria,1QSAH@1224|Proteobacteria,1T01I@1236|Gammaproteobacteria,1X6KV@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_17260_2 913325.N799_02495 1.93e-101 300.0 COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,1RQBJ@1236|Gammaproteobacteria,1X3NW@135614|Xanthomonadales 135614|Xanthomonadales E Phenylalanine-4-hydroxylase phhA - 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 - R01795,R07211 RC00490 ko00000,ko00001,ko01000 - - - Biopterin_H k141_13828_1 1207063.P24_01690 3.17e-212 607.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JPB3@204441|Rhodospirillales 204441|Rhodospirillales C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 k141_15904_1 472759.Nhal_0783 4.21e-231 651.0 COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,1RSFG@1236|Gammaproteobacteria,1WW9R@135613|Chromatiales 135613|Chromatiales F Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit - - 3.6.3.14,3.6.3.15 ko:K02117 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002,ko01000 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn k141_6093_1 1288826.MSNKSG1_17176 1.78e-23 95.1 COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,1S2CW@1236|Gammaproteobacteria,466G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) ybfF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - ko:K01175 - - - - ko00000,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_6093_2 1288826.MSNKSG1_17181 1.07e-265 727.0 COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria,469RD@72275|Alteromonadaceae 1236|Gammaproteobacteria G Strictosidine synthase - - - - - - - - - - - - Str_synth k141_6093_3 1288826.MSNKSG1_17186 1.63e-108 312.0 COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1S6RI@1236|Gammaproteobacteria,4685M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase superfamily protein - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2,Acyl-ACP_TE k141_6093_4 1288826.MSNKSG1_17191 2.93e-234 644.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,467KX@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_6093_5 1288826.MSNKSG1_17196 0.0 1179.0 COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,4657N@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,TrkA_N k141_20151_1 1121940.AUDZ01000013_gene482 1.69e-249 690.0 COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,1RQD9@1236|Gammaproteobacteria,1XS7C@135619|Oceanospirillales 135619|Oceanospirillales Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_20151_2 1232683.ADIMK_0270 4.31e-122 355.0 COG1028@1|root,COG1028@2|Bacteria,1MXNX@1224|Proteobacteria,1RQVH@1236|Gammaproteobacteria,46CIN@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short_C2 k141_20151_3 1042375.AFPL01000015_gene2201 1.9e-243 675.0 COG0654@1|root,COG0654@2|Bacteria,1N7Z4@1224|Proteobacteria,1T2DG@1236|Gammaproteobacteria 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - 1.14.14.11 ko:K14481 ko00643,ko01100,ko01120,map00643,map01100,map01120 - R05488 RC03238 ko00000,ko00001,ko01000 - - - F420_oxidored k141_20151_4 1197906.CAJQ02000023_gene2564 3.57e-36 130.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,3JRDM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_4118_2 395493.BegalDRAFT_1514 1.45e-12 63.2 COG5481@1|root,COG5481@2|Bacteria 2|Bacteria S small protein containing a coiled-coil domain MA20_03740 - - - - - - - - - - - DUF465 k141_20152_1 1027273.GZ77_12495 5.43e-74 240.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XII4@135619|Oceanospirillales 135619|Oceanospirillales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_9732_1 396588.Tgr7_1007 5.35e-258 728.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales 135613|Chromatiales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_6930_1 290400.Jann_1351 1.78e-18 84.3 COG1593@1|root,COG1593@2|Bacteria,1MUHY@1224|Proteobacteria,2TS43@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Trap dicarboxylate transporter, dctm subunit - - - - - - - - - - - - DctM k141_6930_2 246200.SPO0592 1.23e-89 266.0 COG3090@1|root,COG3090@2|Bacteria,1RBHY@1224|Proteobacteria,2U681@28211|Alphaproteobacteria,4NB8Z@97050|Ruegeria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_6930_3 391626.OAN307_c31960 4.18e-118 347.0 COG1638@1|root,COG1638@2|Bacteria,1PFSU@1224|Proteobacteria,2TVA1@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Trap dicarboxylate transporter, dctp subunit - - - - - - - - - - - - DctP k141_15299_1 575586.HMPREF0016_03345 0.000158 45.8 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,3NKHT@468|Moraxellaceae 1236|Gammaproteobacteria L Insertion element 4 transposase N-terminal - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 k141_15299_2 1042375.AFPL01000007_gene2814 1.19e-20 92.8 COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,464GA@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG3385 FOG Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,Nterm_IS4 k141_15299_3 1122599.AUGR01000022_gene1619 0.0 1535.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_15299_4 1278309.KB907103_gene1155 4.06e-76 230.0 2ECFC@1|root,336DK@2|Bacteria,1NFTF@1224|Proteobacteria,1SF9V@1236|Gammaproteobacteria,1XMA3@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15299_5 1278309.KB907103_gene1156 3.66e-180 514.0 2DMMJ@1|root,32SFS@2|Bacteria,1N3DK@1224|Proteobacteria,1T003@1236|Gammaproteobacteria,1XM1Z@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9733_1 519989.ECTPHS_13927 4.34e-23 99.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_9734_1 1237149.C900_02380 4.89e-75 241.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia 976|Bacteroidetes O PDZ domain (Also known as DHR or GLGF) htrA - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 k141_4122_1 1278309.KB907107_gene1647 2.19e-131 378.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XJA6@135619|Oceanospirillales 135619|Oceanospirillales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_15301_1 525897.Dbac_2229 8.32e-11 70.9 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2M919@213115|Desulfovibrionales 28221|Deltaproteobacteria K Sterol-sensing domain of SREBP cleavage-activation - - - ko:K07003 - - - - ko00000 - - - MMPL k141_20153_1 1380394.JADL01000013_gene758 5.11e-10 60.5 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,2JSN4@204441|Rhodospirillales 204441|Rhodospirillales S Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Pribosyltran k141_20153_2 857087.Metme_2776 5.51e-239 696.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_11831_1 1415754.JQMK01000012_gene921 4.4e-97 298.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4659W@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1061 DNA or RNA helicases of superfamily II yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k141_11831_2 1396858.Q666_05430 1.6e-70 214.0 2BWGD@1|root,2ZRHA@2|Bacteria,1P96J@1224|Proteobacteria,1SVNG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11831_3 1288826.MSNKSG1_10473 1.25e-128 367.0 COG4122@1|root,COG4122@2|Bacteria,1QXFR@1224|Proteobacteria,1T3AR@1236|Gammaproteobacteria,466XS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_11831_4 1288826.MSNKSG1_10458 5.64e-110 316.0 COG1047@1|root,COG1047@2|Bacteria,1RGXG@1224|Proteobacteria,1S6XS@1236|Gammaproteobacteria,467IN@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 slyD1 - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_11831_5 1288826.MSNKSG1_10453 1.52e-83 249.0 COG0589@1|root,COG0589@2|Bacteria,1NB6E@1224|Proteobacteria,1SEN6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T universal stress protein - - - - - - - - - - - - Usp k141_11831_6 1288826.MSNKSG1_10448 1.03e-183 513.0 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,46AMD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - 3.1.4.54 ko:K13985 ko04723,map04723 - - - ko00000,ko00001,ko01000 - - - Lactamase_B_2 k141_9735_1 722419.PH505_am00970 1.53e-07 52.0 COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SEIB@1236|Gammaproteobacteria,2Q37Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria N COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) flgM - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM k141_6933_1 1288826.MSNKSG1_13932 2e-101 306.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_6933_2 1288826.MSNKSG1_13927 4.24e-283 777.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,4675Z@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR k141_9736_2 396588.Tgr7_1989 1.8e-13 73.2 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S43R@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_11832_1 1278309.KB907103_gene1132 1.25e-65 210.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XHIG@135619|Oceanospirillales 135619|Oceanospirillales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_11832_2 1278309.KB907103_gene1133 4.19e-172 482.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1XHKU@135619|Oceanospirillales 135619|Oceanospirillales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_11832_3 1278309.KB907103_gene1134 1.11e-60 193.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XHYS@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_4123_1 1255043.TVNIR_1763 1.45e-23 97.4 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1WWMU@135613|Chromatiales 135613|Chromatiales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_4123_2 314345.SPV1_09338 9.21e-188 538.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria 1224|Proteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_15303_1 323261.Noc_1573 4.58e-44 150.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_6934_1 396588.Tgr7_2224 6.92e-126 371.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_11833_1 580332.Slit_1671 4.63e-58 197.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales 28216|Betaproteobacteria C Oxidoreductase FAD-binding domain protein ascD - 1.17.1.1 ko:K00523,ko:K18248 ko00520,ko00627,ko01120,map00520,map00627,map01120 M00637 R00823,R00825,R03391,R03392 RC00192,RC00230 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_20156_1 1278309.KB907104_gene958 3.31e-61 194.0 COG0730@1|root,COG0730@2|Bacteria,1QSM5@1224|Proteobacteria,1RW3X@1236|Gammaproteobacteria,1XI10@135619|Oceanospirillales 135619|Oceanospirillales S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_20156_2 1278309.KB907104_gene959 1.5e-119 343.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1XJ6Q@135619|Oceanospirillales 135619|Oceanospirillales D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA - - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_20156_3 1278309.KB907104_gene960 9.22e-27 105.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XHR1@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_6935_1 697282.Mettu_0150 2.97e-24 100.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1XETK@135618|Methylococcales 135618|Methylococcales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_15304_1 1123401.JHYQ01000002_gene2652 4.35e-57 187.0 COG3751@1|root,COG3751@2|Bacteria,1NBA8@1224|Proteobacteria,1SKR2@1236|Gammaproteobacteria 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_4 k141_11834_1 1278309.KB907108_gene1583 6.89e-41 144.0 COG0583@1|root,COG0583@2|Bacteria,1R5BA@1224|Proteobacteria,1S4S1@1236|Gammaproteobacteria,1XRND@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_6288_2 398720.MED217_07216 9.03e-50 176.0 COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia,2XICX@283735|Leeuwenhoekiella 976|Bacteroidetes G Domain of unknown function (DUF3416) glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 k141_10467_1 1122201.AUAZ01000023_gene3017 8.34e-163 457.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,4643V@72275|Alteromonadaceae 1236|Gammaproteobacteria G Class II aldolase fucA_2 - - - - - - - - - - - Aldolase_II k141_16044_1 1384054.N790_08170 8.96e-22 92.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1XB0U@135614|Xanthomonadales 135614|Xanthomonadales I CDP-alcohol phosphatidyltransferase - - - - - - - - - - - - CDP-OH_P_transf k141_20929_1 1408444.JHYC01000010_gene1533 1.25e-95 297.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1JDCB@118969|Legionellales 118969|Legionellales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA rsmB GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB k141_20929_2 187272.Mlg_2625 4.62e-33 124.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 k141_20929_3 1335757.SPICUR_00285 2.66e-123 381.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_15354_1 1288826.MSNKSG1_08528 4.67e-119 348.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,46573@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 ATP-grasp k141_15354_2 1288826.MSNKSG1_08533 2.03e-144 406.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,4648W@72275|Alteromonadaceae 1236|Gammaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050 Sod_Fe_C,Sod_Fe_N k141_15354_3 1288826.MSNKSG1_08538 0.0 1013.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase bifA - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_3 k141_4194_1 1266914.ATUK01000013_gene1849 7.36e-102 321.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WW6D@135613|Chromatiales 135613|Chromatiales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_5592_2 396588.Tgr7_2056 2.52e-21 90.9 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1WYVY@135613|Chromatiales 135613|Chromatiales O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB - - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_11172_1 207954.MED92_11214 2.36e-188 534.0 COG2271@1|root,COG2271@2|Bacteria,1QX38@1224|Proteobacteria,1T35H@1236|Gammaproteobacteria,1XKGR@135619|Oceanospirillales 135619|Oceanospirillales G Uncharacterised MFS-type transporter YbfB - - - - - - - - - - - - MFS_1 k141_7689_1 1278309.KB907105_gene1448 1.18e-100 299.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XIGU@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_21624_1 391624.OIHEL45_01425 1e-60 195.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,2U1PY@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind k141_21624_2 1123237.Salmuc_00505 2.33e-20 87.8 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,2U0DD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD - 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_18839_1 225937.HP15_3551 1.68e-37 134.0 COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,1RQ0M@1236|Gammaproteobacteria,465A3@72275|Alteromonadaceae 1236|Gammaproteobacteria S PKHD-type hydroxylase ybiX - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 k141_18839_2 768671.ThimaDRAFT_3392 1.72e-29 111.0 28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria,1WY0Y@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_5593_1 999611.KI421504_gene788 2.61e-73 235.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,27ZM8@191028|Leisingera 28211|Alphaproteobacteria H Elongator protein 3, MiaB family, Radical SAM hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_718_1 1095769.CAHF01000011_gene2009 2.07e-69 218.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2VPF9@28216|Betaproteobacteria 28216|Betaproteobacteria S Short-chain dehydrogenase reductase (SDR) - - - - - - - - - - - - adh_short k141_718_2 743299.Acife_3015 7.68e-99 302.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RMXA@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Fad linked oxidase dprE1 - - - - - - - - - - - ALO,FAD_binding_4 k141_17436_1 1288826.MSNKSG1_04011 1.58e-73 228.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_17436_2 1288826.MSNKSG1_04006 1.01e-103 300.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,466U9@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3360 YgbB k141_17436_3 1288826.MSNKSG1_04001 1.42e-149 422.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,466GI@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2747,iBWG_1329.BWG_2483,iEC55989_1330.EC55989_3019,iECDH10B_1368.ECDH10B_2915,iECDH1ME8569_1439.ECDH1ME8569_2657,iECIAI1_1343.ECIAI1_2848,iECO103_1326.ECO103_3289,iECO111_1330.ECO111_3471,iECO26_1355.ECO26_3816,iECSE_1348.ECSE_2999,iECW_1372.ECW_m2953,iEKO11_1354.EKO11_1022,iEcDH1_1363.EcDH1_0941,iEcE24377_1341.EcE24377A_3048,iEcHS_1320.EcHS_A2885,iEcolC_1368.EcolC_0965,iJO1366.b2747,iJR904.b2747,iPC815.YPO3361,iSBO_1134.SBO_2773,iSDY_1059.SDY_2946,iSSON_1240.SSON_2895,iSbBS512_1146.SbBS512_E3127,iUMNK88_1353.UMNK88_3422,iWFL_1372.ECW_m2953,iY75_1357.Y75_RS14300 IspD k141_17436_4 1288826.MSNKSG1_03996 4.44e-54 169.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,46898@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - ko:K05589 - - - - ko00000,ko03036 - - - DivIC k141_13957_1 177437.HRM2_24290 9.84e-122 370.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,42NCP@68525|delta/epsilon subdivisions,2WJSM@28221|Deltaproteobacteria,2MI5K@213118|Desulfobacterales 28221|Deltaproteobacteria M HAD-superfamily hydrolase, subfamily IIB - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth k141_6986_1 511.JT27_10685 3.57e-67 206.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,3T3XB@506|Alcaligenaceae 28216|Betaproteobacteria E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_6986_2 396588.Tgr7_0591 1.56e-45 150.0 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1X2HD@135613|Chromatiales 135613|Chromatiales S MazG-like family - - - - - - - - - - - - MazG-like k141_6986_4 395493.BegalDRAFT_1084 3.09e-43 154.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales 72273|Thiotrichales E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k141_9074_1 1237149.C900_00743 0.000403 51.2 COG0784@1|root,COG0784@2|Bacteria,4NHFX@976|Bacteroidetes,47YCW@768503|Cytophagia 976|Bacteroidetes T PAS domain - - - - - - - - - - - - PAS_3,PAS_8,PAS_9,Response_reg k141_20231_1 765912.Thimo_1044 4.99e-17 81.6 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales 135613|Chromatiales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_20231_2 497321.C664_13764 1.77e-28 127.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales 206389|Rhodocyclales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_9,Response_reg k141_4895_1 1278309.KB907111_gene3355 1.04e-84 254.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,1XJFZ@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_4895_2 207954.MED92_10794 2.69e-136 395.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1XHVA@135619|Oceanospirillales 135619|Oceanospirillales C Converts isocitrate to alpha ketoglutarate icdA - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_16045_1 1122599.AUGR01000014_gene532 1.1e-93 282.0 COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,1XIPW@135619|Oceanospirillales 135619|Oceanospirillales O Peptidase family U32 - - - - - - - - - - - - Peptidase_U32 k141_1411_1 1318628.MARLIPOL_04045 4.12e-123 356.0 COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,1RNDJ@1236|Gammaproteobacteria,4668A@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds mhpF - 1.2.1.10,1.2.1.87 ko:K18366 ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220 M00569 R00228,R01172,R09097 RC00004,RC00184,RC01195 br01602,ko00000,ko00001,ko00002,ko01000 - - - AcetDehyd-dimer,Semialdhyde_dh k141_1411_2 1122201.AUAZ01000005_gene633 8.67e-158 444.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria,46533@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - 4.2.1.132,4.2.1.80 ko:K18364 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02601,R05864 RC00750,RC02676 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_16747_1 519989.ECTPHS_05200 1.99e-126 372.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RRGA@1236|Gammaproteobacteria,1WX0C@135613|Chromatiales 135613|Chromatiales E Belongs to the alpha-IPM synthase homocitrate synthase family - - 2.3.3.14 ko:K02594 ko00620,map00620 - R00271 RC00004,RC00067,RC02754 ko00000,ko00001,ko01000 - - - HMGL-like k141_3498_2 1288826.MSNKSG1_05161 3.18e-129 378.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,463YH@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iE2348C_1286.E2348C_4372,iJN746.PP_4187 Pyr_redox_2,Pyr_redox_dim k141_2955_2 715451.ambt_11860 3.24e-32 125.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k141_16889_1 697282.Mettu_2900 4.87e-63 197.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XF8T@135618|Methylococcales 135618|Methylococcales O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_16889_2 1249627.D779_0418 5.31e-41 140.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales 135613|Chromatiales E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 k141_20406_2 1288826.MSNKSG1_08873 1.43e-165 463.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,466V7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0066 yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - - - - - - - - - - UPF0066 k141_20406_3 1288826.MSNKSG1_08878 0.0 1451.0 COG0642@1|root,COG0784@1|root,COG2197@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,463ZD@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - CHASE5,HATPase_c,HisKA,Hpt,Response_reg k141_20406_4 1288826.MSNKSG1_08883 1.22e-42 139.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,468WS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - ko:K09862 - - - - ko00000 - - - YacG k141_20406_5 1288826.MSNKSG1_08888 3.8e-133 377.0 2E609@1|root,330PP@2|Bacteria,1NA0P@1224|Proteobacteria,1SCFG@1236|Gammaproteobacteria,468PR@72275|Alteromonadaceae 1236|Gammaproteobacteria S YfaZ precursor - - - - - - - - - - - - YfaZ k141_20406_6 1288826.MSNKSG1_08893 1.63e-232 657.0 2FJNS@1|root,34BBY@2|Bacteria,1NZSG@1224|Proteobacteria,1ST2V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_137_1 765911.Thivi_2987 2.29e-62 220.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3 k141_5767_1 1286093.C266_13944 5.27e-83 262.0 COG3206@1|root,COG3206@2|Bacteria,1QA2F@1224|Proteobacteria,2VPIJ@28216|Betaproteobacteria,1K482@119060|Burkholderiaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k141_5767_2 637389.Acaty_c1934 1.14e-112 333.0 28MEU@1|root,2ZASF@2|Bacteria,1R7N3@1224|Proteobacteria,1RYFK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM Phage recombination protein Bet - - - - - - - - - - - - RecT k141_5767_3 1121921.KB898707_gene949 8.76e-11 60.5 COG0847@1|root,COG0847@2|Bacteria,1RE6T@1224|Proteobacteria,1S5FC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L dna polymerase iii - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_18989_1 1131553.JIBI01000009_gene1246 3.75e-149 430.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2WBQH@28216|Betaproteobacteria,3747Z@32003|Nitrosomonadales 28216|Betaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_9192_1 1323663.AROI01000008_gene2519 5.47e-45 169.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_2956_1 1122137.AQXF01000006_gene728 1.95e-62 204.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM k141_2956_2 1122137.AQXF01000006_gene727 3.16e-17 78.2 COG4665@1|root,COG4665@2|Bacteria,1RK2F@1224|Proteobacteria,2UAK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_18282_1 571166.KI421509_gene3504 4.82e-167 493.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria 28211|Alphaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P k141_18282_2 388401.RB2150_01319 8.3e-60 187.0 2E129@1|root,32WI1@2|Bacteria,1NVE4@1224|Proteobacteria,2URU9@28211|Alphaproteobacteria,3ZIFA@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - SnoaL_2 k141_16173_1 1278309.KB907111_gene3371 9.72e-103 325.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,1XIUF@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the peptidase M16 family - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_3659_2 1452718.JBOY01000020_gene686 8.77e-46 162.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_3659_3 547144.HydHO_0146 3.66e-16 79.3 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria 2|Bacteria T EAL domain yliE GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 2.7.7.65,3.1.4.52 ko:K20962,ko:K21023 ko02025,ko05111,map02025,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_3,PAS_9,SBP_bac_3,dCache_1 k141_9890_1 225849.swp_3858 1.4e-08 62.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q8RK@267890|Shewanellaceae 1236|Gammaproteobacteria NT PFAM histidine kinase, HAMP region domain protein - - - ko:K03406,ko:K10937 ko02020,ko02030,ko05111,map02020,map02030,map05111 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_1556_2 1198452.Jab_1c14020 5.71e-17 80.5 COG0834@1|root,COG0834@2|Bacteria,1RD01@1224|Proteobacteria,2VMAG@28216|Betaproteobacteria,478VK@75682|Oxalobacteraceae 28216|Betaproteobacteria ET ABC-type amino acid transport signal transduction systems periplasmic component domain - - - - - - - - - - - - - k141_12710_1 1122212.AULO01000012_gene1087 6.94e-125 370.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XHGP@135619|Oceanospirillales 135619|Oceanospirillales S ATPase components of ABC transporters with duplicated ATPase domains - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_19682_2 1036674.A28LD_1161 2.59e-37 139.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,2QFW2@267893|Idiomarinaceae 1236|Gammaproteobacteria S Virulence factor BrkB rbn GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_11358_1 187272.Mlg_0452 8.37e-158 484.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_16890_2 483219.LILAB_12355 6.07e-38 135.0 28R6X@1|root,2ZDKX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_5013_1 1250232.JQNJ01000001_gene1388 1.72e-15 76.3 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia 976|Bacteroidetes M Opacity protein - - - - - - - - - - - - OMP_b-brl_2 k141_2957_1 1232683.ADIMK_2359 5.29e-96 294.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,464WP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_4357_1 243233.MCA0131 8.7e-17 79.7 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XEXY@135618|Methylococcales 135618|Methylococcales S SURF1-like protein - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_4357_2 105559.Nwat_3092 4.79e-45 155.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SWXH@1236|Gammaproteobacteria,1X1CE@135613|Chromatiales 135613|Chromatiales S signal sequence binding - - - - - - - - - - - - - k141_4357_3 1033802.SSPSH_003320 2.66e-94 286.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_5768_1 870187.Thini_0272 4.47e-95 297.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - - - - - - - - - - STAS,Sulfate_transp k141_5768_2 1123393.KB891316_gene1988 2.86e-06 48.9 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,1KSEK@119069|Hydrogenophilales 119069|Hydrogenophilales P von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA k141_16174_1 292415.Tbd_2047 4.6e-31 115.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1KSPA@119069|Hydrogenophilales 119069|Hydrogenophilales O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase k141_16174_2 713586.KB900536_gene2984 1.21e-55 178.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1WYD7@135613|Chromatiales 135613|Chromatiales O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_5014_1 400668.Mmwyl1_2685 6.96e-79 253.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XHEU@135619|Oceanospirillales 135619|Oceanospirillales S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM k141_3661_1 748280.NH8B_4124 6.73e-29 119.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KQEM@206351|Neisseriales 206351|Neisseriales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_18991_1 1232683.ADIMK_1910 4.06e-49 164.0 COG1846@1|root,COG1846@2|Bacteria,1RJS8@1224|Proteobacteria,1SY8U@1236|Gammaproteobacteria,46BDI@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_27,MarR k141_8523_1 1288826.MSNKSG1_13417 1.02e-41 142.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,464ZE@72275|Alteromonadaceae 1236|Gammaproteobacteria D ATPase involved in cell division ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_8523_2 1288826.MSNKSG1_13422 3.69e-227 632.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,464WP@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_8523_3 1288826.MSNKSG1_13427 2.89e-134 381.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,467AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k141_1558_1 870187.Thini_3406 5.89e-80 261.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales 72273|Thiotrichales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_21132_1 765912.Thimo_0110 7.9e-77 251.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales 135613|Chromatiales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_19 k141_13419_1 298386.PBPRA0409 5.34e-62 215.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XTMU@135623|Vibrionales 135623|Vibrionales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0003674,GO:0003824,GO:0004386,GO:0005488,GO:0005524,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_2958_1 477974.Daud_1971 3.81e-38 140.0 2DBB9@1|root,2Z86U@2|Bacteria,1V3GX@1239|Firmicutes,24M6S@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k141_19683_1 55601.VANGNB10_cI0223c 1.42e-37 137.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XTBR@135623|Vibrionales 135623|Vibrionales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_19683_2 1205753.A989_01245 5.94e-60 200.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1X3U0@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar motor protein motB2 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_21748_1 713586.KB900536_gene37 1.95e-29 120.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria 1224|Proteobacteria L double-strand break repair protein AddB addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_2234_2 1188252.AJYK01000054_gene378 4.99e-100 295.0 COG1280@1|root,COG1280@2|Bacteria,1RA7V@1224|Proteobacteria,1S5TR@1236|Gammaproteobacteria,1Y2QF@135623|Vibrionales 135623|Vibrionales E LysE type translocator - - - - - - - - - - - - LysE k141_140_1 944480.ATUV01000001_gene493 2.3e-40 141.0 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2M6MX@213113|Desulfurellales 28221|Deltaproteobacteria S PFAM peptidase M50 - - - - - - - - - - - - Peptidase_M50 k141_140_2 661367.LLO_2550 8.79e-17 77.4 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1SC4Z@1236|Gammaproteobacteria,1JEEB@118969|Legionellales 118969|Legionellales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_8524_1 351016.RAZWK3B_14034 7.21e-25 99.0 COG3647@1|root,COG3647@2|Bacteria,1RGJN@1224|Proteobacteria,2U80P@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Membrane - - - - - - - - - - - - - k141_8524_2 1211115.ALIQ01000018_gene2160 2.06e-10 59.3 COG2755@1|root,COG2755@2|Bacteria,1N7J4@1224|Proteobacteria,2TY8H@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Stress responsive A/B Barrel Domain - - - - - - - - - - - - Dabb k141_1559_1 765914.ThisiDRAFT_1725 1.86e-127 374.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_2959_1 1121035.AUCH01000001_gene2019 5.09e-18 82.8 COG1960@1|root,COG1960@2|Bacteria,1NDQ8@1224|Proteobacteria,2WGB5@28216|Betaproteobacteria,2KX0F@206389|Rhodocyclales 206389|Rhodocyclales I Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_N k141_2959_2 748658.KB907318_gene1008 5e-45 149.0 COG3439@1|root,COG3439@2|Bacteria,1NMII@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_2959_3 296591.Bpro_4853 2.54e-07 51.6 COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,2VMGS@28216|Betaproteobacteria,4ADB5@80864|Comamonadaceae 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_14823_1 1207076.ALAT01000076_gene1650 5.06e-28 121.0 COG1203@1|root,COG1203@2|Bacteria,1R2FC@1224|Proteobacteria,1T5PT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L CRISPR-associated helicase, Cas3 - - - - - - - - - - - - - k141_3662_1 1278309.KB907099_gene2602 3.66e-72 230.0 COG0439@1|root,COG0439@2|Bacteria,1R5XW@1224|Proteobacteria,1RYYE@1236|Gammaproteobacteria,1XIUC@135619|Oceanospirillales 135619|Oceanospirillales I Biotin carboxylase - - - - - - - - - - - - CPSase_L_D2 k141_3662_2 1278309.KB907099_gene2603 2.68e-56 184.0 COG4927@1|root,COG4927@2|Bacteria,1MY0W@1224|Proteobacteria,1RRGV@1236|Gammaproteobacteria,1XIEG@135619|Oceanospirillales 135619|Oceanospirillales S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT k141_8525_2 187272.Mlg_0671 1.5e-40 148.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF k141_10640_1 349521.HCH_04233 1.42e-114 351.0 COG2204@1|root,COG2204@2|Bacteria,1NH9G@1224|Proteobacteria,1RRF2@1236|Gammaproteobacteria,1XNSF@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat k141_10640_2 1144275.COCOR_01877 2.5e-15 74.7 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage tail sheath protein - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k141_16891_2 357808.RoseRS_0130 7.82e-133 387.0 COG0451@1|root,COG0451@2|Bacteria,2G5PB@200795|Chloroflexi,37576@32061|Chloroflexia 32061|Chloroflexia M short-chain dehydrogenase reductase SDR - - - - - - - - - - - - Epimerase k141_5771_1 1123518.ARWI01000001_gene1185 2.06e-77 241.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k141_18284_1 316274.Haur_4407 0.000109 45.1 COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi,375U0@32061|Chloroflexia 32061|Chloroflexia O Belongs to the thioredoxin family - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_18284_2 870187.Thini_4102 1.9e-46 151.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_8550_1 697282.Mettu_2701 5.68e-39 145.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XE8E@135618|Methylococcales 135618|Methylococcales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_19700_1 1288826.MSNKSG1_14997 0.0 983.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,46421@72275|Alteromonadaceae 1236|Gammaproteobacteria L ATP-dependent helicase HrpB hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_21150_1 1122201.AUAZ01000020_gene2731 2.86e-19 88.2 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,465C2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k141_21150_2 1278309.KB907100_gene1801 8.5e-58 185.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1XH6N@135619|Oceanospirillales 135619|Oceanospirillales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_12031_1 1232683.ADIMK_4116 5.76e-124 365.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,1RU2M@1236|Gammaproteobacteria,46C0S@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD binding domain - - - - - - - - - - - - FAD_binding_2 k141_1575_1 713586.KB900536_gene238 4.53e-39 150.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1S7R5@1236|Gammaproteobacteria,1X0KN@135613|Chromatiales 135613|Chromatiales S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid k141_5794_1 203122.Sde_2082 4.55e-10 67.8 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,4646P@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_15555_2 713586.KB900536_gene838 1.62e-55 187.0 COG2267@1|root,COG2267@2|Bacteria,1N2KV@1224|Proteobacteria 1224|Proteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_19013_1 1397527.Q670_10355 2.94e-94 278.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1XHB3@135619|Oceanospirillales 135619|Oceanospirillales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_3798_2 1278309.KB907102_gene70 5.25e-99 294.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1XJJQ@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_19176_1 1278971.AOGF01000045_gene639 3.41e-23 100.0 COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,1SZQV@1236|Gammaproteobacteria,1YAXA@135625|Pasteurellales 1236|Gammaproteobacteria L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595 k141_13540_2 1288826.MSNKSG1_06183 8.6e-25 100.0 COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,1RXYN@1236|Gammaproteobacteria,4688B@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxygen-independent coproporphyrinogen III oxidase - - - - - - - - - - - - Radical_SAM k141_4525_1 626887.J057_14570 1.54e-119 353.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_5166_1 1232683.ADIMK_0776 2.44e-240 671.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1T0DP@1236|Gammaproteobacteria,469T2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_10802_2 1453500.AT05_06455 1.28e-30 117.0 COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes 976|Bacteroidetes G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_1738_1 1123504.JQKD01000005_gene4706 6.57e-18 81.3 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,4AEEP@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 k141_14239_1 1168067.JAGP01000001_gene482 7.2e-69 216.0 COG0847@1|root,COG0847@2|Bacteria,1MXM2@1224|Proteobacteria,1T2MD@1236|Gammaproteobacteria,462WC@72273|Thiotrichales 72273|Thiotrichales L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_14239_2 1168067.JAGP01000001_gene481 9.68e-20 82.8 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria 1236|Gammaproteobacteria T universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_8673_1 545276.KB898724_gene1763 6.05e-97 313.0 COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_7292_1 436308.Nmar_0558 1.26e-17 83.6 arCOG08027@1|root,arCOG08027@2157|Archaea,41T8U@651137|Thaumarchaeota 2157|Archaea D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - ko:K22222 - - - - ko00000,ko04812 - - - - k141_17036_1 29730.Gorai.002G166100.1 2.7e-08 51.2 2EPT8@1|root,2SSXZ@2759|Eukaryota,38132@33090|Viridiplantae,3GMMD@35493|Streptophyta 35493|Streptophyta - - - - - - - - - - - - - - - k141_2397_1 1331660.L313_0628 7.53e-99 308.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,3NKCF@468|Moraxellaceae 1236|Gammaproteobacteria C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_5901_1 929558.SMGD1_0678 3.72e-71 234.0 294BG@1|root,2ZRRP@2|Bacteria,1RG32@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF4384,LPP20 k141_16316_1 1042375.AFPL01000013_gene2463 1.59e-284 778.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,4648G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Peptidase dimerisation domain amaB_2 - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_321_1 998674.ATTE01000001_gene3255 3.22e-18 85.5 28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,462BI@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF3549) - - - - - - - - - - - - DUF3549 k141_9332_1 349521.HCH_03024 6.87e-36 128.0 COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,1S976@1236|Gammaproteobacteria,1XKK4@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_9332_3 1249975.JQLP01000005_gene627 1.3e-27 103.0 COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2P6Z2@244698|Gillisia 976|Bacteroidetes S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_3139_1 1123401.JHYQ01000015_gene1347 2.59e-52 171.0 COG2258@1|root,COG2258@2|Bacteria,1PVVI@1224|Proteobacteria,1SB64@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MOSC domain - - - - - - - - - - - - MOSC k141_3799_1 1177154.Y5S_01704 2.02e-60 211.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_10038_2 1323663.AROI01000003_gene2319 1.16e-179 519.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_18427_1 1196835.A458_20315 5.53e-22 95.9 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1Z10Q@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria U alanine symporter agcS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp k141_18427_2 1232683.ADIMK_3157 7.92e-265 734.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,46D87@72275|Alteromonadaceae 1236|Gammaproteobacteria E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k141_18427_3 207954.MED92_06388 1.2e-145 421.0 COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RMUB@1236|Gammaproteobacteria,1XHXN@135619|Oceanospirillales 135619|Oceanospirillales EJ PFAM Asparaginase glutaminase ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_18427_4 1187848.AJYQ01000075_gene1603 1.96e-110 330.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,1XSI8@135623|Vibrionales 135623|Vibrionales P COG0598 Mg2 and Co2 transporters - - - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_13541_1 935261.JAGL01000006_gene2265 3e-113 335.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,43IK5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I Belongs to the thiolase family pcaF - 2.3.1.16,2.3.1.174,2.3.1.9 ko:K00626,ko:K00632,ko:K07823 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_6545_1 580332.Slit_2150 4.02e-76 238.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_6545_2 1207076.ALAT01000089_gene1008 5.97e-06 50.4 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1Z2A1@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Zn-dependent protease with chaperone function Z012_09445 - - - - - - - - - - - Peptidase_M48 k141_7293_1 1026882.MAMP_01930 3.72e-91 287.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales 72273|Thiotrichales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k141_19822_1 1278309.KB907099_gene3050 3.85e-94 283.0 COG0500@1|root,COG2226@2|Bacteria,1RBIZ@1224|Proteobacteria,1S2E3@1236|Gammaproteobacteria,1XJC7@135619|Oceanospirillales 135619|Oceanospirillales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_19822_2 1278309.KB907099_gene3049 9.27e-261 726.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XHGN@135619|Oceanospirillales 135619|Oceanospirillales JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_19822_3 1278309.KB907099_gene3048 4.87e-151 431.0 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_1753_1 1278309.KB907101_gene579 9.14e-151 438.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XHB9@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_5911_1 1168067.JAGP01000001_gene2236 1.66e-05 52.4 COG2317@1|root,COG2317@2|Bacteria,1NNNJ@1224|Proteobacteria 1224|Proteobacteria E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - - - - - - - - - - - BatD k141_8692_1 1249627.D779_0601 5.37e-142 421.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1WWDA@135613|Chromatiales 135613|Chromatiales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr k141_8692_2 720554.Clocl_1050 1e-46 156.0 COG2954@1|root,COG2954@2|Bacteria,1V6JS@1239|Firmicutes 1239|Firmicutes S Adenylate cyclase - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 - - - - - - - - - - CYTH k141_2418_3 1288826.MSNKSG1_08198 1e-49 163.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,467DA@72275|Alteromonadaceae 1236|Gammaproteobacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - ko:K02197 - - - - ko00000 - - iSSON_1240.SSON_2255 CcmE k141_2418_4 395493.BegalDRAFT_2461 7.19e-79 254.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4623I@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein CcmF C-terminal - - - - - - - - - - - - CcmF_C,Cytochrom_C_asm k141_3155_1 1288826.MSNKSG1_06573 3.43e-175 495.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_15666_1 637905.SVI_3111 9.63e-47 160.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,2QAQH@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM OmpW family protein ompW GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K07275 - - - - ko00000 - - - OmpW k141_15666_2 765913.ThidrDRAFT_2111 7.04e-95 281.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1WWJX@135613|Chromatiales 135613|Chromatiales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_15666_3 391615.ABSJ01000023_gene357 1.78e-46 157.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1J4ME@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_19194_1 765912.Thimo_2160 1.69e-76 245.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales 135613|Chromatiales U sulphate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_339_1 1278309.KB907099_gene3006 2.57e-82 251.0 COG0583@1|root,COG0583@2|Bacteria,1QU1H@1224|Proteobacteria,1RYFY@1236|Gammaproteobacteria,1XH6S@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_339_2 1278309.KB907099_gene3008 5.12e-23 96.7 COG0031@1|root,COG0031@2|Bacteria,1MUR6@1224|Proteobacteria,1RMS1@1236|Gammaproteobacteria,1XIJC@135619|Oceanospirillales 135619|Oceanospirillales E Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_339_3 1278309.KB907099_gene3009 1.26e-186 520.0 2DB6N@1|root,2Z7HZ@2|Bacteria,1PQ9P@1224|Proteobacteria,1RRV9@1236|Gammaproteobacteria,1XHYY@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4392) - - - - - - - - - - - - DUF4392 k141_17053_1 1278309.KB907107_gene1704 1.79e-284 800.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHWH@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis protein histidine kinase and related - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_11498_1 388051.AUFE01000007_gene1443 2.53e-101 317.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae 28216|Betaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_4542_1 1288826.MSNKSG1_17900 3.73e-236 673.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,464B1@72275|Alteromonadaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_1754_1 519989.ECTPHS_06552 1.23e-58 195.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1WXK9@135613|Chromatiales 135613|Chromatiales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_8066_1 998674.ATTE01000001_gene520 1.74e-106 320.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales 72273|Thiotrichales H PFAM aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_2419_1 502025.Hoch_2925 5.07e-46 169.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2YYJV@29|Myxococcales 28221|Deltaproteobacteria M Rhs family - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN,Tox-PL-2,VCBS,ZU5 k141_5912_1 1517681.HW45_25645 3.65e-44 162.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1SWH8@1236|Gammaproteobacteria,1XVAI@135623|Vibrionales 135623|Vibrionales I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc_2 k141_10060_1 1415778.JQMM01000001_gene856 8.4e-07 50.1 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1J4HG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_10060_2 243233.MCA2437 3.37e-10 59.3 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1XF1V@135618|Methylococcales 135618|Methylococcales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ k141_6560_1 1118235.CAJH01000067_gene3601 6.93e-16 71.6 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1X7EI@135614|Xanthomonadales 135614|Xanthomonadales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_6560_2 523791.Kkor_0445 7.45e-19 79.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XM6U@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_6560_3 491952.Mar181_3349 4.67e-78 234.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1XJ5K@135619|Oceanospirillales 135619|Oceanospirillales J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_6560_4 395493.BegalDRAFT_2618 2.24e-120 348.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,45ZXA@72273|Thiotrichales 72273|Thiotrichales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_6560_5 396588.Tgr7_2319 4.61e-53 169.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1WYH7@135613|Chromatiales 135613|Chromatiales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k141_21961_1 1500890.JQNL01000001_gene624 1.37e-92 288.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1X3J8@135614|Xanthomonadales 135614|Xanthomonadales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_12895_1 1122603.ATVI01000007_gene1619 3.73e-122 365.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1X4BH@135614|Xanthomonadales 135614|Xanthomonadales P chloride channel clcA - - - - - - - - - - - Voltage_CLC k141_2420_1 118797.XP_007454233.1 2.93e-24 101.0 COG1012@1|root,COG4992@1|root,KOG1402@2759|Eukaryota,KOG2451@2759|Eukaryota,38D8C@33154|Opisthokonta,3BG29@33208|Metazoa,3CRS6@33213|Bilateria,486DF@7711|Chordata,48YRP@7742|Vertebrata,3JBAN@40674|Mammalia,4J144@91561|Cetartiodactyla 33208|Metazoa C Succinate-semialdehyde dehydrogenase, mitochondrial-like - - - - - - - - - - - - Aldedh k141_2420_2 391619.PGA1_c17990 1.47e-52 174.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,34ETG@302485|Phaeobacter 28211|Alphaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh k141_340_2 1179778.PMM47T1_07381 1.06e-35 129.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thiol disulfide interchange protein dsbA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k141_3156_1 697282.Mettu_3982 7.21e-78 253.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XE26@135618|Methylococcales 135618|Methylococcales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_19,TPR_6 k141_18437_1 1123255.JHYS01000004_gene1018 2.64e-13 81.6 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4ABCW@80864|Comamonadaceae 28216|Betaproteobacteria T ATP-binding region, ATPase domain protein pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_8694_2 85643.Tmz1t_2032 1.19e-13 75.9 COG1524@1|root,COG1524@2|Bacteria,1R2II@1224|Proteobacteria,2VMR9@28216|Betaproteobacteria,2KW7I@206389|Rhodocyclales 206389|Rhodocyclales S type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_19823_1 1278309.KB907101_gene717 3.59e-185 517.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XHW1@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_21962_1 1207075.PputUW4_00908 3.33e-82 260.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_12196_1 717773.Thicy_1107 1.03e-49 167.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1S6AG@1236|Gammaproteobacteria,46251@72273|Thiotrichales 72273|Thiotrichales O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_10061_1 1121895.Q765_01600 1.32e-17 79.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia,2NV4Z@237|Flavobacterium 976|Bacteroidetes K AraC family transcriptional - - - - - - - - - - - - HTH_18 k141_10061_2 983545.Glaag_4490 4.79e-49 177.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_17055_1 1122137.AQXF01000001_gene3209 5.34e-47 157.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_12896_2 1356852.N008_11220 1.19e-05 47.8 COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,47JFG@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_341_1 1121875.KB907549_gene1940 1.46e-90 293.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia 976|Bacteroidetes M Tricorn protease homolog - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ k141_19950_1 948106.AWZT01000007_gene3536 1.25e-68 213.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1K11Z@119060|Burkholderiaceae 28216|Betaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_2532_1 83406.HDN1F_11480 2.32e-18 93.2 2B3X8@1|root,31WM6@2|Bacteria,1RFUV@1224|Proteobacteria,1RNAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3999) - - - - - - - - - - - - DUF3999 k141_1868_1 290400.Jann_2833 2.34e-21 95.1 2DBS0@1|root,2ZANT@2|Bacteria,1R8Y3@1224|Proteobacteria,2U146@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_17176_1 367336.OM2255_09321 2.96e-57 183.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_5368_1 998088.B565_1559 3.68e-42 152.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1Y4QA@135624|Aeromonadales 135624|Aeromonadales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate - - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_12358_1 1121921.KB898706_gene2392 5.83e-22 97.1 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,2PNI5@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_9456_1 555778.Hneap_0470 7.3e-21 96.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X09E@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_8192_1 1283300.ATXB01000002_gene2877 1e-97 297.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1XE9R@135618|Methylococcales 135618|Methylococcales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_15075_1 1278309.KB907102_gene16 5.59e-141 415.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XIEY@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 k141_15075_2 686340.Metal_1801 7.69e-42 140.0 COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1RUKI@1236|Gammaproteobacteria,1XGHP@135618|Methylococcales 135618|Methylococcales J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP k141_7448_1 509635.N824_17370 4.67e-38 145.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia 976|Bacteroidetes P TonB-dependent receptor plug domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_3292_2 396588.Tgr7_3162 6.56e-32 124.0 COG2132@1|root,COG2132@2|Bacteria,1REHU@1224|Proteobacteria,1SZ88@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q PFAM multicopper oxidase type - - - - - - - - - - - - Cu-oxidase_3 k141_12359_2 291112.PAU_01832 2.03e-20 91.7 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyl-transferase rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_16470_1 857087.Metme_2463 1.66e-95 288.0 COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF2167 k141_18577_1 105559.Nwat_1281 9.83e-91 271.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1WWRQ@135613|Chromatiales 135613|Chromatiales S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA k141_18577_2 1301098.PKB_3511 1.03e-42 157.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Zn-dependent protease with chaperone function - - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_9457_1 1049564.TevJSym_bn00210 1.49e-16 79.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,1S21F@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT k141_3293_1 380703.AHA_3247 1.15e-89 287.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1Y3ND@135624|Aeromonadales 135624|Aeromonadales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_22066_1 1283300.ATXB01000002_gene2944 3.11e-53 179.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1XDVC@135618|Methylococcales 135618|Methylococcales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_15076_1 748658.KB907320_gene882 4.16e-82 266.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales 135613|Chromatiales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_10212_2 1485545.JQLW01000005_gene860 6.28e-41 147.0 COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria 1224|Proteobacteria M Salt-induced outer membrane protein ydiY - - ko:K07283 - - - - ko00000 - - - DUF481 k141_10212_4 1266908.AQPB01000034_gene675 6e-107 321.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_10212_5 1123502.AQXD01000001_gene753 1.45e-23 99.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1X4K3@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - - - - - - - - - - HemN_C,Radical_SAM k141_13740_1 644282.Deba_2031 4.71e-96 292.0 COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Linear amide C-N hydrolases, choloylglycine hydrolase family - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH k141_17177_1 1380394.JADL01000016_gene411 2.19e-98 322.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_486_1 1278309.KB907100_gene1920 1.53e-35 125.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1XRF8@135619|Oceanospirillales 135619|Oceanospirillales L NUDIX domain - - - - - - - - - - - - NUDIX k141_486_2 1278309.KB907100_gene1918 5.51e-28 102.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SGHW@1236|Gammaproteobacteria,1XMQ0@135619|Oceanospirillales 135619|Oceanospirillales S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k141_486_3 1278309.KB907100_gene1917 1.17e-58 182.0 COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,1SAV8@1236|Gammaproteobacteria,1XK5M@135619|Oceanospirillales 135619|Oceanospirillales S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP k141_486_4 1278309.KB907100_gene1916 5.16e-248 686.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1XH4G@135619|Oceanospirillales 135619|Oceanospirillales P Mg2 and Co2 transporter CorB - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_486_5 1278309.KB907100_gene1915 1.8e-142 407.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1XI5V@135619|Oceanospirillales 135619|Oceanospirillales S cytochrome C - - - - - - - - - - - - Cytochrom_C_asm k141_486_6 1278309.KB907100_gene1914 1.54e-204 574.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1XIPR@135619|Oceanospirillales 135619|Oceanospirillales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_3919_1 1288826.MSNKSG1_10928 1.54e-36 136.0 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,1RQSW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - COX2,Cupredoxin_1 k141_3919_2 1288826.MSNKSG1_10933 0.0 1436.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria,465B0@72275|Alteromonadaceae 1236|Gammaproteobacteria CK Regulator of nitric oxide reductase transcription nosR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19339 - - - - ko00000,ko03000 - - - FMN_bind,Fer4,Fer4_5 k141_3919_3 1288826.MSNKSG1_10938 1.08e-90 265.0 2CG3F@1|root,32S32@2|Bacteria,1N1SR@1224|Proteobacteria,1SBQB@1236|Gammaproteobacteria,468ES@72275|Alteromonadaceae 1236|Gammaproteobacteria S Ribonucleotide reductase subunit alpha - - - - - - - - - - - - - k141_3919_4 1288826.MSNKSG1_10943 5.25e-91 266.0 COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,1S936@1236|Gammaproteobacteria,4684E@72275|Alteromonadaceae 1236|Gammaproteobacteria S DGC domain - - - - - - - - - - - - DGC k141_3919_5 1288826.MSNKSG1_10948 5.43e-175 488.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases dnrS - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_1201_1 1122201.AUAZ01000001_gene2493 2.91e-116 342.0 COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,1RMUP@1236|Gammaproteobacteria,46CP2@72275|Alteromonadaceae 1236|Gammaproteobacteria E Creatinase/Prolidase N-terminal domain - - 3.5.3.3 ko:K08688 ko00260,ko00330,ko01100,map00260,map00330,map01100 - R01566 RC00548,RC00549 ko00000,ko00001,ko01000 - - - Creatinase_N,Peptidase_M24 k141_1201_2 911045.PSE_1836 1.6e-96 292.0 COG1638@1|root,COG1638@2|Bacteria,1NU34@1224|Proteobacteria,2VFZE@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP k141_11613_1 317013.NY99_03385 8.03e-12 65.1 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1X4N0@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_11613_2 330214.NIDE3382 9.82e-47 157.0 2ECCV@1|root,336B4@2|Bacteria,3J18G@40117|Nitrospirae 40117|Nitrospirae - - - - - - - - - - - - - - - k141_11613_4 83406.HDN1F_23080 2.29e-10 57.4 2ED2F@1|root,336ZC@2|Bacteria,1N758@1224|Proteobacteria,1SE5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 k141_19951_1 1496688.ER33_03045 1.02e-26 105.0 COG0500@1|root,COG2226@2|Bacteria,1G60J@1117|Cyanobacteria,22T7D@167375|Cyanobium 1117|Cyanobacteria Q SAM (And some other nucleotide) binding motif - - - - - - - - - - - - Methyltransf_11 k141_19951_2 637905.SVI_2140 2.69e-42 142.0 2E6Y2@1|root,331HC@2|Bacteria,1N7EH@1224|Proteobacteria,1SE1K@1236|Gammaproteobacteria,2QCPK@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18578_1 870187.Thini_1173 2.5e-67 212.0 COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T3U6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family - - 2.1.1.156 ko:K18896 ko00260,map00260 - R10060 RC00003,RC03038 ko00000,ko00001,ko01000 - - - Methyltransf_25 k141_10946_1 1415780.JPOG01000001_gene891 0.000457 42.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1X3CN@135614|Xanthomonadales 135614|Xanthomonadales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k141_10946_2 216142.LT40_18885 3.87e-79 246.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 RibD_C,dCMP_cyt_deam_1 k141_22067_1 292415.Tbd_2028 0.00014 45.1 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1KSX1@119069|Hydrogenophilales 119069|Hydrogenophilales P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_22067_2 1116375.VEJY3_21616 2.61e-26 106.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP synthase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_15833_1 686340.Metal_2805 1.52e-71 218.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1XF45@135618|Methylococcales 135618|Methylococcales S PFAM Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 k141_15833_2 545276.KB898725_gene665 1.24e-33 124.0 COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1X1I8@135613|Chromatiales 135613|Chromatiales CO Glutathione peroxidase - - - - - - - - - - - - AhpC-TSA,Redoxin k141_1871_1 1121406.JAEX01000039_gene2094 5.57e-07 57.4 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria 28221|Deltaproteobacteria NT PFAM chemotaxis sensory transducer - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_3295_1 945543.VIBR0546_05638 2.58e-11 59.7 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,1XYE9@135623|Vibrionales 135623|Vibrionales T Belongs to the BolA IbaG family bolA GO:0008150,GO:0008360,GO:0022603,GO:0022604,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008 - ko:K05527 - - - - ko00000,ko03000 - - - BolA k141_2536_1 313594.PI23P_10365 9.62e-27 104.0 2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1I66X@117743|Flavobacteriia,3VWRC@52959|Polaribacter 976|Bacteroidetes S Family of unknown function (DUF5362) - - - - - - - - - - - - DUF5362 k141_10213_1 4081.Solyc01g007640.2.1 3.29e-202 617.0 2CMQD@1|root,2QRDV@2759|Eukaryota,37QIN@33090|Viridiplantae,3GEA1@35493|Streptophyta,44PKI@71274|asterids 35493|Streptophyta C Plant protein of unknown function (DUF825) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009509,GO:0009532,GO:0009536,GO:0009570,GO:0009575,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464 - - - - - - - - - - AAA,DUF825 k141_10947_1 301.JNHE01000040_gene89 3.81e-69 223.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1YFDM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J RNA cap guanine-N2 methyltransferase rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_16471_1 1415779.JOMH01000001_gene1529 2.87e-82 260.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1XCHU@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_16471_2 1123517.JOMR01000001_gene1458 5.97e-88 263.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,4609I@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_1872_1 90813.JQMT01000001_gene1376 4.26e-78 244.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,4607R@72273|Thiotrichales 72273|Thiotrichales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_2537_1 523791.Kkor_1130 1.79e-30 111.0 COG1586@1|root,COG1586@2|Bacteria,1RH88@1224|Proteobacteria,1S7BA@1236|Gammaproteobacteria,1XPK8@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine - - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_2537_2 95619.PM1_0220760 1.23e-64 204.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_0125,iPC815.YPO3411,iSDY_1059.SDY_0028 Spermine_synt_N,Spermine_synth k141_21409_1 1278309.KB907109_gene3301 1.56e-36 129.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1XK24@135619|Oceanospirillales 135619|Oceanospirillales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_21409_2 1278309.KB907109_gene3300 1.36e-202 564.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1XHX5@135619|Oceanospirillales 135619|Oceanospirillales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_21409_3 1278309.KB907109_gene3299 3.87e-163 459.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1XIQ5@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_21409_4 1278309.KB907109_gene3298 5.1e-116 337.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria,1XHSX@135619|Oceanospirillales 135619|Oceanospirillales F Glutamine amidotransferase class-I - - - - - - - - - - - - GATase k141_9468_1 1177179.A11A3_16530 7.7e-37 134.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RZ5E@1236|Gammaproteobacteria,1XH3B@135619|Oceanospirillales 135619|Oceanospirillales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_12377_1 1278309.KB907111_gene3363 5.86e-264 745.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XH4C@135619|Oceanospirillales 135619|Oceanospirillales D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_1887_1 1288826.MSNKSG1_09048 4.74e-82 244.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,467RH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_1887_2 1288826.MSNKSG1_09053 1.68e-189 527.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,466U1@72275|Alteromonadaceae 1236|Gammaproteobacteria S amidohydrolase ramA - 3.5.5.1 ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_1887_3 1288826.MSNKSG1_09058 2.75e-62 212.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_4700_1 1380387.JADM01000002_gene2236 5.17e-14 69.7 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales 135619|Oceanospirillales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_4700_2 1134474.O59_000184 9.46e-16 78.2 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1FH9N@10|Cellvibrio 1236|Gammaproteobacteria S SCP-2 sterol transfer family yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_8207_1 1136138.JH604622_gene557 5.68e-26 110.0 COG0768@1|root,COG0769@1|root,COG0768@2|Bacteria,COG0769@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PBP_dimer,Transpeptidase k141_8207_2 1168065.DOK_14109 2.23e-34 132.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1J4BW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PBP_dimer,Transpeptidase k141_19967_1 765913.ThidrDRAFT_0025 2.22e-56 201.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - - - - - - - - - - CheW,HATPase_c,Hpt,Response_reg k141_17199_1 1163409.UUA_17090 9.84e-70 231.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1X37V@135614|Xanthomonadales 135614|Xanthomonadales N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_17199_2 519989.ECTPHS_04658 1.48e-33 127.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1WW1K@135613|Chromatiales 135613|Chromatiales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_8794_1 1278309.KB907101_gene740 2.24e-94 280.0 COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1S27E@1236|Gammaproteobacteria,1XQXN@135619|Oceanospirillales 135619|Oceanospirillales J S4 RNA-binding domain - - - - - - - - - - - - PseudoU_synth_2 k141_8794_2 1278309.KB907101_gene743 5.29e-47 157.0 COG0705@1|root,COG0705@2|Bacteria,1NG54@1224|Proteobacteria,1SF6D@1236|Gammaproteobacteria,1XMEP@135619|Oceanospirillales 135619|Oceanospirillales S Rhomboid family - - - - - - - - - - - - Rhomboid k141_14477_2 697282.Mettu_4074 1.26e-99 304.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XDR3@135618|Methylococcales 135618|Methylococcales K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_13200_1 472759.Nhal_0879 5.28e-77 240.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1WXJR@135613|Chromatiales 135613|Chromatiales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase k141_11719_2 1288826.MSNKSG1_06993 0.0 972.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,4660P@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein involved in propionate catabolism prpD GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - iEcolC_1368.EcolC_3291 MmgE_PrpD k141_11719_3 1288826.MSNKSG1_06998 2e-283 774.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,464AI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria prpF - - ko:K09788 ko00640,map00640 - R11264 RC03405 ko00000,ko00001,ko01000 - - - PrpF k141_11719_4 1288826.MSNKSG1_07003 0.0 1710.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,465HN@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnD GO:0003674,GO:0003824,GO:0003994,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 4.2.1.117,4.2.1.3 ko:K01681,ko:K20455 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900,R11263 RC00497,RC00498,RC00618,RC01152 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_11719_5 1288826.MSNKSG1_07008 2.7e-67 213.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,465RE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the citrate synthase family prpC GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630 Citrate_synt k141_20773_1 585503.HMPREF7545_1744 8.58e-10 71.2 2DBPZ@1|root,2ZABJ@2|Bacteria,1VJIG@1239|Firmicutes,4H5QI@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k141_13880_1 519989.ECTPHS_01504 2.46e-81 250.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_13880_2 314278.NB231_11579 1.41e-19 84.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1WVVY@135613|Chromatiales 135613|Chromatiales E imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD k141_10371_1 1237149.C900_00641 4.31e-73 222.0 COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,47P7N@768503|Cytophagia 976|Bacteroidetes K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_2679_1 1122201.AUAZ01000014_gene276 6.41e-108 322.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1SYZ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,Cupin_2,HTH_18 k141_2679_2 1122201.AUAZ01000036_gene1230 8.65e-213 595.0 COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,1RXYY@1236|Gammaproteobacteria,46CG0@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Cytochrome P450 - - - - - - - - - - - - p450 k141_6788_1 697282.Mettu_1547 2.67e-99 301.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XEHZ@135618|Methylococcales 135618|Methylococcales C FAD linked oxidases, C-terminal domain - - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_1983_1 439235.Dalk_5267 6.99e-34 134.0 COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3 k141_1347_1 76869.PputGB1_4694 2.39e-54 193.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1YXP2@136845|Pseudomonas putida group 1236|Gammaproteobacteria T Histidine kinase cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_8902_1 1111728.ATYS01000032_gene1610 4.63e-40 136.0 COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,1S5XH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_8902_2 202954.BBNK01000001_gene785 1.5e-29 106.0 COG1670@1|root,COG1670@2|Bacteria,1N9F9@1224|Proteobacteria,1SCFK@1236|Gammaproteobacteria,3NPCG@468|Moraxellaceae 1236|Gammaproteobacteria J Protein of unknown function (DUF3565) - - - - - - - - - - - - DUF3565 k141_8902_3 319795.Dgeo_2148 5.74e-28 118.0 COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1WMF2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9 k141_16615_1 1288826.MSNKSG1_15047 4.01e-189 530.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,46A3E@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family speC - 4.1.1.17,4.1.1.20 ko:K01581,ko:K01586 ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230 M00016,M00134,M00525,M00526,M00527 R00451,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0864 Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_16615_2 1288826.MSNKSG1_15042 0.0 1075.0 COG0840@1|root,COG3829@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,1QW3X@1224|Proteobacteria,1RM9S@1236|Gammaproteobacteria,4655H@72275|Alteromonadaceae 1236|Gammaproteobacteria KNT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - 3.1.3.3 ko:K03406,ko:K07315 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035,ko03021 - - - MCPsignal,PAS,PAS_9,SpoIIE k141_16615_3 1288826.MSNKSG1_15037 2.97e-204 564.0 COG0189@1|root,COG0189@2|Bacteria,1MWQA@1224|Proteobacteria,1RPD7@1236|Gammaproteobacteria,4664B@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_16615_4 1288826.MSNKSG1_15032 1.37e-221 612.0 COG2207@1|root,COG2207@2|Bacteria,1R5D8@1224|Proteobacteria,1RYEI@1236|Gammaproteobacteria,46B2H@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_16615_5 1288826.MSNKSG1_15027 6.88e-314 855.0 COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RY92@1236|Gammaproteobacteria,466U4@72275|Alteromonadaceae 1236|Gammaproteobacteria P flavoprotein involved in K transport - - - ko:K07222 - - - - ko00000 - - - FMO-like,Pyr_redox_3 k141_16615_6 1288826.MSNKSG1_15022 1.64e-208 577.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,46A32@72275|Alteromonadaceae 1236|Gammaproteobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF k141_16615_7 1288826.MSNKSG1_15017 1.13e-145 415.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,469BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_13881_1 1417296.U879_04175 8.59e-82 249.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria 28211|Alphaproteobacteria O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_12517_1 1278309.KB907103_gene1168 6e-142 402.0 COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,1RP21@1236|Gammaproteobacteria,1XHQF@135619|Oceanospirillales 135619|Oceanospirillales I transferase scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_12517_2 1278309.KB907103_gene1169 5.83e-52 169.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,1RNXB@1236|Gammaproteobacteria,1XHNK@135619|Oceanospirillales 135619|Oceanospirillales I transferase scoA - 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_19436_1 289376.THEYE_A0544 1.32e-30 121.0 COG1912@1|root,COG1912@2|Bacteria,3J0RG@40117|Nitrospirae 40117|Nitrospirae S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans k141_19436_3 1565129.JSFF01000007_gene1520 1.43e-19 87.8 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,2Q9A7@267890|Shewanellaceae 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_14478_1 743836.AYNA01000111_gene18 1.61e-33 119.0 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,370RI@31993|Methylocystaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 k141_14478_2 748658.KB907321_gene813 1.07e-07 51.6 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1WZIV@135613|Chromatiales 135613|Chromatiales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_22210_1 1288826.MSNKSG1_14927 0.0 1107.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1SJP8@1236|Gammaproteobacteria,46D4Y@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,EAL,GGDEF,PAS,PAS_9,Response_reg,dCache_1,dCache_3 k141_22210_2 1288826.MSNKSG1_14932 1.57e-147 416.0 COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,1S6US@1236|Gammaproteobacteria,46871@72275|Alteromonadaceae 1236|Gammaproteobacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - k141_22210_3 1288826.MSNKSG1_14937 2.1e-150 424.0 2AEBT@1|root,31468@2|Bacteria,1RC39@1224|Proteobacteria,1S7QQ@1236|Gammaproteobacteria,468QT@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22210_4 1288826.MSNKSG1_14942 2.1e-304 832.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,46598@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0534 Na -driven multidrug efflux pump dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k141_22210_5 1288826.MSNKSG1_14947 6.34e-276 754.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,465CG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_13224_1 1123518.ARWI01000001_gene1244 4.92e-122 358.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,461TG@72273|Thiotrichales 72273|Thiotrichales P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 k141_3451_1 911239.CF149_12454 1.15e-25 102.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S esterase yqiA GO:0003674,GO:0003824,GO:0016787,GO:0016788 - ko:K07000 - - - - ko00000 - - - UPF0227 k141_3451_2 690850.Desaf_2363 2.17e-49 164.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria 1224|Proteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - k141_1995_1 644107.SL1157_0722 7.96e-81 247.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria,4N9YS@97050|Ruegeria 28211|Alphaproteobacteria M Mechanosensitive ion channel mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix k141_10397_1 595460.RRSWK_06401 2.31e-104 317.0 COG0389@1|root,COG0389@2|Bacteria,2IZ2I@203682|Planctomycetes 203682|Planctomycetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_12537_1 1266908.AQPB01000035_gene137 2.5e-48 159.0 2EFAS@1|root,3393N@2|Bacteria,1NDQN@1224|Proteobacteria,1SSBD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12537_2 870187.Thini_0169 0.0 876.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RYJX@1236|Gammaproteobacteria,46213@72273|Thiotrichales 72273|Thiotrichales G Ribulose bisphosphate carboxylase large chain, catalytic domain - - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_4833_1 1255043.TVNIR_2978 2.62e-87 266.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales 135613|Chromatiales K LysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_4011_1 1278309.KB907107_gene1723 7.69e-34 124.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XHXX@135619|Oceanospirillales 135619|Oceanospirillales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_4011_2 1278309.KB907107_gene1724 0.0 931.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XHZ3@135619|Oceanospirillales 135619|Oceanospirillales N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_4011_3 1278309.KB907107_gene1725 2.48e-59 185.0 COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,1XKZR@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook-basal body complex protein FliE fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_4011_4 1278309.KB907107_gene1726 1.43e-134 382.0 COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,1S6UR@1236|Gammaproteobacteria,1XJU3@135619|Oceanospirillales 135619|Oceanospirillales L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_4011_5 1278309.KB907107_gene1727 0.0 1048.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XHCM@135619|Oceanospirillales 135619|Oceanospirillales T signal-transduction protein containing cAMP-binding and CBS domains - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_4011_6 1278309.KB907107_gene1728 0.0 1076.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1XHJP@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_4011_7 1278309.KB907107_gene1729 5.27e-45 146.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1XKTS@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF4212 k141_4011_8 1278309.KB907107_gene1730 0.0 1700.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales 135619|Oceanospirillales T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_9624_2 1182590.BN5_03464 2.94e-35 131.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1YICB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Processivity clamp loader gamma complex DNA pol III C-term holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta k141_8356_1 1288826.MSNKSG1_13952 6.69e-160 449.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E (ABC) transporter - - 3.6.3.21 ko:K02028,ko:K02029 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_8356_2 1288826.MSNKSG1_13957 2.79e-143 405.0 COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,1RXTD@1236|Gammaproteobacteria 1236|Gammaproteobacteria E amino acid ABC transporter yckA - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_8356_3 1288826.MSNKSG1_13962 2.62e-263 723.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464KF@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed - - - - - - - - - - - - Thiolase_C,Thiolase_N k141_8356_4 1288826.MSNKSG1_13967 4.48e-06 47.4 COG0624@1|root,COG0624@2|Bacteria,1MW2W@1224|Proteobacteria,1S1T9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_2693_2 754477.Q7C_1644 7.21e-55 176.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,460SM@72273|Thiotrichales 72273|Thiotrichales Q MlaD protein mlaD - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_13904_1 1278309.KB907099_gene2498 7.87e-68 212.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S5VC@1236|Gammaproteobacteria,1XS69@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 k141_13904_2 1278309.KB907099_gene2499 1.73e-96 284.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S46K@1236|Gammaproteobacteria,1XK45@135619|Oceanospirillales 135619|Oceanospirillales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_11729_2 323261.Noc_0457 8.19e-111 325.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1WWNN@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine - - 2.4.2.28,2.4.2.44 ko:K00772,ko:K19696 ko00270,ko01100,map00270,map01100 M00034 R01402,R09668 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_11729_3 28258.KP05_02865 5.31e-26 100.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1XJQK@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_15187_1 344747.PM8797T_02329 2.01e-23 101.0 COG0025@1|root,COG0025@2|Bacteria,2IZBZ@203682|Planctomycetes 203682|Planctomycetes P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_15187_3 1283300.ATXB01000001_gene760 2.48e-05 45.1 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1S4VI@1236|Gammaproteobacteria,1XF76@135618|Methylococcales 135618|Methylococcales O PFAM Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_17331_1 1415754.JQMK01000002_gene2087 7.74e-75 225.0 COG0346@1|root,COG0346@2|Bacteria,1N2NJ@1224|Proteobacteria,1SB2Z@1236|Gammaproteobacteria,46BD4@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase,Glyoxalase_2 k141_1996_1 1116472.MGMO_83c00160 1.91e-84 265.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XESH@135618|Methylococcales 135618|Methylococcales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_5521_2 1122130.AUHN01000006_gene1870 5.52e-10 59.3 COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0035601,GO:0036211,GO:0040007,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0098732,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_14497_1 754476.Q7A_2662 4.54e-71 220.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_21560_1 223926.28809544 3.19e-115 365.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales 135623|Vibrionales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,dCache_1 k141_21560_2 326297.Sama_1966 2.94e-15 74.3 COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,2Q9A5@267890|Shewanellaceae 1236|Gammaproteobacteria S S1 domain cvfB - - ko:K00243 - - - - ko00000 - - - S1_2 k141_1366_1 1349767.GJA_2879 1.55e-06 50.8 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2VHXH@28216|Betaproteobacteria,4723V@75682|Oxalobacteraceae 28216|Betaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD k141_18760_1 633131.TR2A62_0028 0.000289 45.8 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall hydrolyses involved in spore germination sleB - - - - - - - - - - - Hydrolase_2 k141_18760_2 1122211.JMLW01000018_gene873 8.11e-54 178.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1XRS3@135619|Oceanospirillales 135619|Oceanospirillales Q Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB - - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_4834_2 999547.KI421500_gene3706 8.98e-13 69.3 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG2041 Sulfite oxidase and related enzymes - - 1.8.3.1 ko:K00387 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00533 RC00168 ko00000,ko00001,ko01000 - - - Mo-co_dimer,Oxidored_molyb k141_8357_1 648757.Rvan_2502 1.64e-60 197.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,3N65W@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885,ko:K01894 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_10399_1 62928.azo0546 5.79e-56 186.0 COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,2VQ5A@28216|Betaproteobacteria,2KWDD@206389|Rhodocyclales 206389|Rhodocyclales O PPIC-type PPIASE domain - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Rotamase k141_7582_2 290400.Jann_1219 5.91e-12 67.8 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase ampD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 ko:K00788,ko:K01447,ko:K03806,ko:K11066 ko00730,ko01100,map00730,map01100 M00127 R03223,R04112,R10712 RC00064,RC00141,RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000,ko01011 - - - Amidase_2,PG_binding_1 k141_5522_1 1353537.TP2_03710 3.18e-49 170.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2XKR6@285107|Thioclava 28211|Alphaproteobacteria LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_8936_1 519989.ECTPHS_12515 2.48e-46 166.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_8936_2 768671.ThimaDRAFT_0203 1.43e-35 136.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WXWN@135613|Chromatiales 135613|Chromatiales I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_15188_1 321846.PS417_27305 2.27e-31 117.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_13905_1 2340.JV46_29040 3.36e-87 273.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1J4T7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iPC815.YPO3762,iSFV_1184.SFV_3651 TrkH k141_13905_2 1038922.PflQ2_5606 9.44e-16 72.0 COG3063@1|root,COG3063@2|Bacteria,1N24B@1224|Proteobacteria,1T0PC@1236|Gammaproteobacteria,1YUH3@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_14,TPR_19,TPR_2,TPR_8 k141_7583_1 519989.ECTPHS_04638 6.52e-16 75.5 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_624_2 198628.Dda3937_00694 6.61e-22 88.2 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,2JECE@204037|Dickeya 1236|Gammaproteobacteria K Belongs to the BolA IbaG family yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - - - - - - - - - - BolA k141_624_3 349124.Hhal_2114 1.4e-133 390.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1WXB6@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_9625_1 1288826.MSNKSG1_01738 3.9e-95 280.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SC7S@1236|Gammaproteobacteria,46931@72275|Alteromonadaceae 1236|Gammaproteobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_9625_2 1288826.MSNKSG1_01743 3.36e-145 421.0 COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,4648Q@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_20279_2 283942.IL0952 2.49e-46 153.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,2QG3U@267893|Idiomarinaceae 1236|Gammaproteobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_19571_1 666685.R2APBS1_2563 5.43e-86 264.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1X3A8@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_15406_1 1049564.TevJSym_ae00650 3.02e-68 214.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_4217_1 697282.Mettu_2003 9.86e-57 184.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1XEIY@135618|Methylococcales 135618|Methylococcales E Belongs to the TrpC family trpC - 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS k141_10517_1 388401.RB2150_08328 1.45e-69 224.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,2TSG7@28211|Alphaproteobacteria,3ZI87@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes sthA - 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_21000_2 290397.Adeh_3711 6.62e-21 84.7 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42XFU@68525|delta/epsilon subdivisions,2WSTK@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_21000_4 472759.Nhal_0023 3.2e-112 338.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_1448_1 595460.RRSWK_04882 1.7e-45 157.0 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 k141_11904_1 349521.HCH_05446 1.13e-87 261.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1XJBH@135619|Oceanospirillales 135619|Oceanospirillales P Zn-ribbon-containing protein involved in phosphonate metabolism - - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_11904_2 1163407.UU7_10551 6.56e-19 79.3 2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11904_3 1279015.KB908455_gene1398 8.82e-21 85.5 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1Y5WJ@135624|Aeromonadales 135624|Aeromonadales S Phosphate-starvation-inducible E - - - ko:K13256 - - - - ko00000 - - - PsiE k141_12612_1 1124780.ANNU01000048_gene2162 2.73e-12 70.1 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity spoIVB - 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Peptidase_S55,Trypsin_2 k141_5647_1 1278309.KB907101_gene659 1.61e-63 214.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XHZN@135619|Oceanospirillales 135619|Oceanospirillales S DNA internalization-related competence protein ComEC Rec2 rec2 - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_5647_2 1278309.KB907101_gene660 4.61e-125 358.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1XJ6W@135619|Oceanospirillales 135619|Oceanospirillales U MotA TolQ ExbB proton channel exbB1 - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_5647_3 1278309.KB907101_gene661 3.1e-71 217.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1XK2S@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein exbD1 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_5647_4 1278309.KB907101_gene662 3.87e-172 488.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XIDE@135619|Oceanospirillales 135619|Oceanospirillales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_5647_5 1278309.KB907101_gene663 5.95e-33 114.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1XM4Y@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p k141_5647_6 1278309.KB907101_gene664 6.74e-167 468.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1XIE8@135619|Oceanospirillales 135619|Oceanospirillales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k141_17458_1 349521.HCH_00752 1.43e-23 99.8 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XHRW@135619|Oceanospirillales 135619|Oceanospirillales P Phosphate transport system permease protein - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_17458_2 472759.Nhal_2290 6.59e-105 326.0 COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1WXXX@135613|Chromatiales 135613|Chromatiales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k141_50_1 1278309.KB907099_gene2930 2.71e-68 228.0 COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,1T3FX@1236|Gammaproteobacteria 1236|Gammaproteobacteria C heat shock protein binding - - - - - - - - - - - - Cytochrome_C7 k141_11237_1 1123399.AQVE01000019_gene1608 2.89e-75 233.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,45ZWI@72273|Thiotrichales 72273|Thiotrichales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_6317_1 1278309.KB907104_gene879 2.39e-116 345.0 COG0330@1|root,COG0330@2|Bacteria,1R93I@1224|Proteobacteria,1RPTI@1236|Gammaproteobacteria,1XINU@135619|Oceanospirillales 135619|Oceanospirillales O SPFH domain / Band 7 family - - - - - - - - - - - - Band_7 k141_19572_1 1279019.ARQK01000050_gene1341 2.61e-54 178.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_7739_1 1049564.TevJSym_ac00730 5.68e-83 259.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1J55H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_15407_1 1278309.KB907100_gene2096 3.1e-131 401.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales 135619|Oceanospirillales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_16080_1 314231.FP2506_17949 1.13e-11 63.9 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_16080_2 472759.Nhal_1618 3.23e-138 390.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RRAN@1236|Gammaproteobacteria,1X04F@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_7 k141_16080_5 472759.Nhal_1615 1.89e-52 179.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,1RP1B@1236|Gammaproteobacteria,1WZVK@135613|Chromatiales 135613|Chromatiales C Prokaryotic cytochrome b561 - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB k141_2836_1 1288826.MSNKSG1_02148 3.35e-208 584.0 COG0477@1|root,COG2814@2|Bacteria,1R3RZ@1224|Proteobacteria,1S072@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_16783_1 765913.ThidrDRAFT_4145 2.26e-169 505.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWAU@135613|Chromatiales 135613|Chromatiales U Hydrophobe Amphiphile Efflux-1 (HAE1) - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_13309_1 111781.Lepto7376_0247 1.28e-07 59.7 COG0236@1|root,COG0318@1|root,COG0596@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,COG0596@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1H927@1150|Oscillatoriales 1117|Cyanobacteria Q Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - - - - - - - - - - AMP-binding,Abhydrolase_1,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt k141_13309_3 999141.GME_01042 2.14e-51 198.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RZ9H@1236|Gammaproteobacteria,1XNKG@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS_9,Response_reg k141_13309_4 314230.DSM3645_12826 0.000259 45.1 2ETUY@1|root,33MC6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_13309_5 631454.N177_3468 1.45e-75 229.0 28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,2U5BA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nucleoside 2-deoxyribosyltransferase YtoQ ytoQ - - - - - - - - - - - Nuc_deoxyri_tr3 k141_13309_7 1049564.TevJSym_ab00180 1.41e-51 169.0 COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,1S8FV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_21002_1 1357279.N018_04115 3.01e-81 261.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1Z92E@136849|Pseudomonas syringae group 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - iG2583_1286.G2583_4754 peroxidase k141_21650_1 1278309.KB907106_gene1240 1.96e-307 846.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1XI43@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase k141_21650_2 1278309.KB907106_gene1241 3.68e-300 824.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XHFK@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_21650_3 1278309.KB907106_gene1242 5.24e-286 800.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHAU@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9,dCache_1 k141_13996_1 443144.GM21_1199 2.44e-18 94.4 COG0642@1|root,COG4251@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X7X2@28221|Deltaproteobacteria 28221|Deltaproteobacteria T response regulator - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_11239_1 1122599.AUGR01000014_gene510 9.36e-29 112.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1XICP@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_748_1 1278309.KB907105_gene1481 6.14e-169 479.0 28Z9U@1|root,2ZM1P@2|Bacteria,1RBFF@1224|Proteobacteria,1S17A@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_748_2 1278309.KB907105_gene1484 0.0 1053.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XJ19@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_748_3 1122599.AUGR01000014_gene633 6.7e-87 266.0 COG0834@1|root,COG0834@2|Bacteria,1RDBZ@1224|Proteobacteria,1S5AT@1236|Gammaproteobacteria,1XJWI@135619|Oceanospirillales 135619|Oceanospirillales ET ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_748_4 1278309.KB907105_gene1486 5.7e-68 207.0 COG3112@1|root,COG3112@2|Bacteria,1RH38@1224|Proteobacteria,1S6EG@1236|Gammaproteobacteria,1XMJ4@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family (UPF0231) - - - ko:K09910 - - - - ko00000 - - - UPF0231 k141_748_5 1232683.ADIMK_3893 1.66e-179 505.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T2N0@1236|Gammaproteobacteria,46CXX@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,MASE4,PAS_3,Y_Y_Y,dCache_1 k141_748_6 314345.SPV1_13182 6.33e-124 362.0 28KJG@1|root,2ZA4H@2|Bacteria,1MUD3@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_5649_1 765912.Thimo_2519 1.62e-46 165.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RQW0@1236|Gammaproteobacteria,1X1HR@135613|Chromatiales 135613|Chromatiales M ABC-type transport system, involved in lipoprotein release, permease component - - - - - - - - - - - - FtsX,MacB_PCD k141_7740_1 1049564.TevJSym_ag00460 2.38e-88 265.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G HAD-hyrolase-like gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 HAD_2 k141_7740_2 225937.HP15_3288 9.16e-38 139.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464I1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0417 Anth_synt_I_N,Chorismate_bind k141_16784_1 2340.JV46_08870 1.76e-104 333.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1J7JF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C k141_21004_1 443152.MDG893_07760 9.04e-136 419.0 COG1061@1|root,COG2227@1|root,COG2932@1|root,COG3886@1|root,COG1061@2|Bacteria,COG2227@2|Bacteria,COG2932@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4657B@72275|Alteromonadaceae 1236|Gammaproteobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,Methyltransf_25,PLDc_2,ResIII k141_2139_1 1283284.AZUK01000001_gene804 2.02e-22 99.8 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1Y4I7@135624|Aeromonadales 135624|Aeromonadales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_19573_1 2340.JV46_09960 3.17e-151 437.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C k141_2837_1 765913.ThidrDRAFT_2128 1.99e-89 277.0 COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria,1WWHR@135613|Chromatiales 135613|Chromatiales I Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 k141_7741_1 396588.Tgr7_1224 1.2e-108 325.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1WVV3@135613|Chromatiales 135613|Chromatiales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_11241_1 1219077.VAZ01S_063_00420 3.26e-48 172.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales 135623|Vibrionales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_11241_2 653733.Selin_0897 1.5e-05 47.8 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria 2|Bacteria M LysM domain CP_0155 - - ko:K08307,ko:K12204 - - - - ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 - - LysM,SLT,T4SS_TraI k141_5650_1 765913.ThidrDRAFT_2299 4.65e-140 431.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_11907_1 1122137.AQXF01000004_gene1573 3.35e-42 155.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2TQUH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase k141_20280_1 1123242.JH636435_gene1855 1.7e-07 58.2 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes 203682|Planctomycetes T FHA domain - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - FHA,GAF_2,SpoIIE k141_20280_2 338963.Pcar_2636 3.77e-25 95.5 COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,42W9B@68525|delta/epsilon subdivisions,2WS2I@28221|Deltaproteobacteria,43SRM@69541|Desulfuromonadales 28221|Deltaproteobacteria S S4 domain - - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 k141_8428_1 935557.ATYB01000009_gene822 4.15e-55 193.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,4B7ZM@82115|Rhizobiaceae 28211|Alphaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase MA20_44845 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_20304_1 314345.SPV1_13062 8.96e-75 236.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria 1224|Proteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family speF - 4.1.1.17,4.1.1.20 ko:K01581,ko:K01586 ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230 M00016,M00134,M00525,M00526,M00527 R00451,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0864 Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_7756_1 29581.BW37_03087 1.2e-05 47.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,4765Q@75682|Oxalobacteraceae 28216|Betaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain creC - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,dCache_3 k141_7756_2 207954.MED92_00335 5.73e-90 284.0 COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1XJS9@135619|Oceanospirillales 135619|Oceanospirillales V Inner membrane protein involved in colicin E2 resistance - - - ko:K06143 - - - - ko00000 - - - CreD k141_6331_1 1415756.JQMY01000001_gene1863 4.09e-141 409.0 COG1653@1|root,COG1653@2|Bacteria,1PF41@1224|Proteobacteria,2VD9U@28211|Alphaproteobacteria,2PFV8@252301|Oceanicola 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_1 k141_14022_1 1121396.KB893095_gene4378 1.76e-12 65.9 COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria,2MKJH@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - - - - - - - - - - DctQ k141_14022_2 1121405.dsmv_0647 9.37e-65 211.0 COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2MJCH@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_765_1 1278309.KB907101_gene523 3.92e-254 704.0 COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria,1XHMN@135619|Oceanospirillales 135619|Oceanospirillales S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k141_765_2 1278309.KB907101_gene522 5.51e-43 148.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XHEF@135619|Oceanospirillales 135619|Oceanospirillales S ATPase, AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_14729_1 998674.ATTE01000001_gene4007 3.24e-110 338.0 COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,463U2@72273|Thiotrichales 72273|Thiotrichales V ABC transporter - - - ko:K13926 - - - - ko00000 - - - ABC2_membrane_3,ABC_tran k141_18193_1 377629.TERTU_3096 7.75e-23 100.0 COG0745@1|root,COG0745@2|Bacteria,1MXD3@1224|Proteobacteria,1RR3G@1236|Gammaproteobacteria,2PQ48@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_5678_1 929558.SMGD1_2070 1e-33 123.0 arCOG05203@1|root,303AI@2|Bacteria,1NZAP@1224|Proteobacteria,430QT@68525|delta/epsilon subdivisions,2YS4S@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria - - - - - - - - - - - - - - - k141_2852_1 1123401.JHYQ01000031_gene3405 6.56e-104 315.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,45ZY0@72273|Thiotrichales 72273|Thiotrichales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_1462_1 1278309.KB907104_gene838 2.05e-203 611.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT Serine threonine protein kinase stk1 - 2.7.11.1 ko:K08282,ko:K11916,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02044 - - - FGE-sulfatase,Pkinase k141_2154_2 1168065.DOK_15449 3.15e-25 103.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1J5SW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG0500 SAM-dependent methyltransferases rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_4377_3 266748.HY04_05035 1.79e-31 117.0 COG0457@1|root,COG0457@2|Bacteria,4NSXM@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 k141_1579_1 572477.Alvin_0220 2.82e-100 301.0 COG0451@1|root,COG0451@2|Bacteria,1MW8N@1224|Proteobacteria,1RSIY@1236|Gammaproteobacteria,1WY4P@135613|Chromatiales 135613|Chromatiales GM NAD dependent epimerase/dehydratase family - - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k141_1579_2 717772.THIAE_04215 2.51e-22 94.0 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,4630A@72273|Thiotrichales 72273|Thiotrichales K Transcription termination factor nusG - - - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_20424_1 523791.Kkor_0752 2.22e-89 280.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XHZZ@135619|Oceanospirillales 135619|Oceanospirillales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_16208_1 1499967.BAYZ01000076_gene804 8.43e-17 77.8 COG3417@1|root,COG3417@2|Bacteria,2NQZZ@2323|unclassified Bacteria 2|Bacteria M Peptidoglycan-synthase activator LpoB lpoB GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07337,ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - LpoB k141_16208_2 391615.ABSJ01000054_gene1466 2.33e-50 167.0 2EUFJ@1|root,33MXU@2|Bacteria,1NZHB@1224|Proteobacteria,1SQC7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LPP20 lipoprotein - - - - - - - - - - - - LPP20 k141_12039_1 83406.HDN1F_06670 1.29e-56 195.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1J4BW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - iSSON_1240.SSON_0092 PBP_dimer,Transpeptidase k141_11376_1 305900.GV64_03915 3.8e-16 73.9 COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,1SBIE@1236|Gammaproteobacteria,1XMWJ@135619|Oceanospirillales 135619|Oceanospirillales P Hemerythrin - - - ko:K07216 - - - - ko00000 - - - Hemerythrin k141_11376_3 261292.Nit79A3_2096 9.28e-157 446.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,372AH@32003|Nitrosomonadales 28216|Betaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k141_11376_4 1158292.JPOE01000002_gene3014 2.23e-227 635.0 COG0446@1|root,COG0446@2|Bacteria,1QSG7@1224|Proteobacteria,2W9DB@28216|Betaproteobacteria,1KKDR@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_11376_5 1134474.O59_001276 7.8e-56 177.0 COG3011@1|root,COG3011@2|Bacteria,1N6ZR@1224|Proteobacteria,1SEXR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 k141_11376_6 1120999.JONM01000003_gene2624 1.18e-90 273.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VJB0@28216|Betaproteobacteria,2KTYT@206351|Neisseriales 206351|Neisseriales K Transcriptional regulatory protein, C terminal - - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_16916_1 1288826.MSNKSG1_17516 8.05e-291 817.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,4643M@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_2252_1 1278309.KB907100_gene2291 1.69e-87 266.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XHRC@135619|Oceanospirillales 135619|Oceanospirillales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_2252_2 1278309.KB907100_gene2290 0.0 1524.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1XHZE@135619|Oceanospirillales 135619|Oceanospirillales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_13447_1 1278309.KB907103_gene1208 4.63e-297 822.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XHBP@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter - - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_13447_2 1278309.KB907103_gene1209 2.15e-40 140.0 COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,1RZJJ@1236|Gammaproteobacteria,1XHUB@135619|Oceanospirillales 135619|Oceanospirillales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 k141_19703_1 1163617.SCD_n01096 3.17e-18 87.4 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - PhosphMutase k141_19703_2 498211.CJA_1614 5.14e-178 518.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1FGUD@10|Cellvibrio 1236|Gammaproteobacteria L DHH family recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_8561_2 1288826.MSNKSG1_05486 4.5e-140 397.0 COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,466V9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Periplasmic protein - - - - - - - - - - - - Peptidase_C93 k141_8561_3 1288826.MSNKSG1_05481 1.35e-23 98.2 COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria,46B77@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases ygcU - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_7156_1 1288826.MSNKSG1_09383 9.97e-130 369.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,466WV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0312 family yceI - - - - - - - - - - - YceI k141_7156_2 1288826.MSNKSG1_09378 0.0 890.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465R0@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_7156_4 1288826.MSNKSG1_09368 0.0 1473.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_7156_5 1288826.MSNKSG1_09363 9.5e-282 771.0 COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,4647E@72275|Alteromonadaceae 1236|Gammaproteobacteria E phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k141_7156_6 1288826.MSNKSG1_09358 0.0 1313.0 COG2199@1|root,COG2200@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2204@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,4663N@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_7156_7 1288826.MSNKSG1_09353 6.34e-305 840.0 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,466J7@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10665_1 580332.Slit_0530 2.47e-191 564.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_15573_1 396588.Tgr7_3082 3.91e-157 447.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQPA@1236|Gammaproteobacteria,1X2CQ@135613|Chromatiales 135613|Chromatiales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 k141_15573_2 1298593.TOL_2413 5.88e-14 70.9 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,1XNXM@135619|Oceanospirillales 135619|Oceanospirillales P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran k141_14866_1 177439.DP0385 2.48e-137 400.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NQ9@68525|delta/epsilon subdivisions,2WM2K@28221|Deltaproteobacteria,2MP9N@213118|Desulfobacterales 28221|Deltaproteobacteria E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.15,4.1.2.27 ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 M00027,M00100 R00261,R00489,R01682,R02464,R02466,R06516 RC00264,RC00299,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000 - - - Pyridoxal_deC k141_20457_1 545276.KB898726_gene1102 1.27e-51 173.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Squalene/phytoene synthase - - - - - - - - - - - - SQS_PSY k141_1602_1 1288826.MSNKSG1_05651 2.25e-33 122.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,465NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit bkdA2 - 1.2.4.4 ko:K00167 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_1602_2 1288826.MSNKSG1_05656 1.67e-102 307.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,4666W@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bkdA1 - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_7171_1 1286106.MPL1_11683 5.01e-24 102.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales 72273|Thiotrichales M PFAM AsmA family - - - ko:K07289 - - - - ko00000 - - - AsmA k141_7171_2 765911.Thivi_1071 6.99e-13 68.9 COG3945@1|root,COG3945@2|Bacteria,1R1KK@1224|Proteobacteria,1T552@1236|Gammaproteobacteria,1X2UQ@135613|Chromatiales 135613|Chromatiales S hemerythrin HHE cation binding domain - - - - - - - - - - - - - k141_4405_1 765911.Thivi_3646 5.93e-73 229.0 28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,1RNYB@1236|Gammaproteobacteria,1WW5I@135613|Chromatiales 135613|Chromatiales H PFAM Dinitrogenase reductase ADP-ribosyltransferase - - 2.4.2.37 ko:K05951 - - - - ko00000,ko01000 - - - DRAT k141_21806_1 2340.JV46_18530 1.02e-56 197.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1J4QN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009436,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iJN746.PP_0356,iWFL_1372.ECW_m3242 Malate_synthase k141_21806_2 1122201.AUAZ01000009_gene2762 3.87e-293 809.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,46AE2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM,DctQ k141_21175_1 1121937.AUHJ01000014_gene2622 4.91e-54 177.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,464UP@72275|Alteromonadaceae 1236|Gammaproteobacteria S NIF3 (NGG1p interacting factor 3) ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - - - - - - - - - - NIF3 k141_19051_1 313606.M23134_00781 1.1e-30 118.0 COG2148@1|root,COG2148@2|Bacteria,4NHSV@976|Bacteroidetes,47M3N@768503|Cytophagia 976|Bacteroidetes M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf,Response_reg k141_5063_1 1082932.ATCR1_23980 6.48e-76 241.0 COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,2TR59@28211|Alphaproteobacteria,4B7NK@82115|Rhizobiaceae 28211|Alphaproteobacteria S Transposase - - - - - - - - - - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 k141_16936_1 543913.D521_1883 3.75e-22 93.6 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,1KPQV@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_16936_2 1121904.ARBP01000003_gene6447 1.92e-59 190.0 COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,47VIF@768503|Cytophagia 976|Bacteroidetes S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_12069_1 396588.Tgr7_0202 2.29e-122 364.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_4406_2 28229.ND2E_1268 3.92e-46 157.0 COG1575@1|root,COG1575@2|Bacteria,1QHA9@1224|Proteobacteria,1TEVV@1236|Gammaproteobacteria,2Q7F8@267889|Colwelliaceae 1236|Gammaproteobacteria H UbiA prenyltransferase family - - - - - - - - - - - - UbiA k141_6459_1 1122599.AUGR01000042_gene3669 4.76e-16 70.9 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10688_1 1278309.KB907110_gene3186 8.02e-145 416.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1XH9Y@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_21807_1 400668.Mmwyl1_2141 7.47e-30 115.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,1XNZR@135619|Oceanospirillales 135619|Oceanospirillales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_21807_2 1297570.MESS4_280117 1.77e-45 155.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,43NIW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_16937_1 1026882.MAMP_02894 3.44e-36 132.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,460SF@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_7172_1 1255043.TVNIR_3782 1.41e-41 144.0 COG3439@1|root,COG3439@2|Bacteria,1RA8I@1224|Proteobacteria,1S34D@1236|Gammaproteobacteria,1WXZJ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_14868_1 314278.NB231_13021 4.94e-65 224.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales 135613|Chromatiales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_21176_1 1123368.AUIS01000007_gene2739 9.45e-88 289.0 COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,2NBVW@225057|Acidithiobacillales 225057|Acidithiobacillales C e3 binding domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim k141_9221_1 1288826.MSNKSG1_02509 5.02e-299 835.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_9221_2 1288826.MSNKSG1_02514 2.93e-106 308.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,4677Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the CinA family ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_9221_3 1288826.MSNKSG1_02519 8.48e-242 665.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,465M8@72275|Alteromonadaceae 1236|Gammaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_9221_4 1288826.MSNKSG1_02524 1.52e-111 320.0 COG0655@1|root,COG0655@2|Bacteria,1RAP5@1224|Proteobacteria,1S3B1@1236|Gammaproteobacteria,468DZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0655 Multimeric flavodoxin WrbA - - - - - - - - - - - - FMN_red k141_9221_5 1288826.MSNKSG1_02529 0.0 1533.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,464FF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase S16 family - - - ko:K04770 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k141_9221_6 1288826.MSNKSG1_02534 1.29e-138 392.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,46AKW@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG4566 Response regulator nodW - - - - - - - - - - - GerE,Response_reg k141_9221_7 1288826.MSNKSG1_02539 0.0 996.0 COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,465JT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fixL - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9,Phosphonate-bd,Response_reg k141_9221_8 1288826.MSNKSG1_02544 1.28e-194 541.0 COG2030@1|root,COG2030@2|Bacteria,1RAAG@1224|Proteobacteria,1S1Z8@1236|Gammaproteobacteria,467RI@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2030 Acyl dehydratase - - - - - - - - - - - - MaoC_dehydrat_N,MaoC_dehydratas k141_9221_9 1288826.MSNKSG1_02549 8.26e-240 659.0 COG2207@1|root,COG2207@2|Bacteria,1NVER@1224|Proteobacteria,1RQWM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_9221_10 1537994.JQFW01000022_gene120 9.12e-11 57.8 2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9221_12 1288826.MSNKSG1_02559 3.03e-238 658.0 COG2207@1|root,COG2207@2|Bacteria,1R6FC@1224|Proteobacteria,1S1MA@1236|Gammaproteobacteria,46CNH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_9221_13 1288826.MSNKSG1_02564 0.0 978.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_18326_2 59196.RICGR_0911 9.88e-13 65.1 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria 1224|Proteobacteria S An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH ygfY GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 k141_18326_3 1049564.TevJSym_cj00020 2.81e-127 366.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1J4VZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Fer2_3,Fer4_17,Fer4_8 k141_18326_4 323848.Nmul_A0861 3.39e-46 165.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,371TZ@32003|Nitrosomonadales 28216|Betaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_5064_2 1026882.MAMP_02063 5.26e-129 373.0 COG1226@1|root,COG1226@2|Bacteria,1QYC1@1224|Proteobacteria 1224|Proteobacteria P COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 k141_6460_2 768671.ThimaDRAFT_3202 4.65e-49 162.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1WW4H@135613|Chromatiales 135613|Chromatiales J PFAM methyltransferase small - - - - - - - - - - - - MTS,MTS_N k141_894_2 203122.Sde_3731 8.12e-177 510.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_894_3 314285.KT71_07129 3.54e-22 90.1 COG2827@1|root,COG2827@2|Bacteria,1QJ9D@1224|Proteobacteria,1TH7Z@1236|Gammaproteobacteria,1JAXE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Containing a URI domain - - - - - - - - - - - - GIY-YIG k141_894_4 1278307.KB906976_gene1540 2.15e-61 202.0 COG0596@1|root,COG0596@2|Bacteria,1RAET@1224|Proteobacteria,1S3KA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase - - - - - - - - - - - - Abhydrolase_1 k141_894_5 1278309.KB907102_gene146 1.31e-53 172.0 2DP61@1|root,330P6@2|Bacteria,1NIV7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_894_6 1042209.HK44_026005 2.27e-34 147.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YQ01@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_894_7 1278309.KB907102_gene144 4.21e-240 667.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XHN1@135619|Oceanospirillales 135619|Oceanospirillales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_21808_1 1037409.BJ6T_12300 1.16e-41 144.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,2U57Q@28211|Alphaproteobacteria,3JVX5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_21808_2 1131553.JIBI01000015_gene672 5.66e-22 95.1 COG2267@1|root,COG2267@2|Bacteria,1N2KV@1224|Proteobacteria 1224|Proteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_20459_1 1288826.MSNKSG1_06838 1.09e-24 103.0 COG1541@1|root,COG1541@2|Bacteria,1RFV4@1224|Proteobacteria,1S519@1236|Gammaproteobacteria 1236|Gammaproteobacteria H COG1541 Coenzyme F390 synthetase - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding k141_20459_2 270374.MELB17_14286 2.09e-62 196.0 COG0110@1|root,COG0110@2|Bacteria,1RDQE@1224|Proteobacteria,1S3RJ@1236|Gammaproteobacteria,466XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (Isoleucine patch superfamily) - - - - - - - - - - - - Hexapep,Hexapep_2 k141_4407_1 1288826.MSNKSG1_13232 1.97e-234 661.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,46676@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_19053_1 1278309.KB907110_gene3172 1.33e-88 264.0 COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,1XI9Z@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase k141_21983_1 644801.Psest_2106 4.22e-10 65.1 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1Z059@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - GGDEF,PAS,PAS_4 k141_16343_2 580332.Slit_2600 7.78e-05 47.8 COG4726@1|root,COG4726@2|Bacteria,1PQMH@1224|Proteobacteria,2W9PQ@28216|Betaproteobacteria,44WM6@713636|Nitrosomonadales 28216|Betaproteobacteria NU Pilus assembly protein PilX - - - ko:K12286 - - - - ko00000,ko02044 - - - - k141_16343_3 243277.VC_0412 0.000318 43.5 COG4966@1|root,COG4966@2|Bacteria,1QUXW@1224|Proteobacteria,1T25G@1236|Gammaproteobacteria,1XW9G@135623|Vibrionales 135623|Vibrionales NU Prokaryotic N-terminal methylation motif mshO - - ko:K12285 - - - - ko00000,ko02044 - - - N_methyl k141_9374_1 1123256.KB907929_gene3380 5.46e-56 203.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1X3AR@135614|Xanthomonadales 135614|Xanthomonadales M AsmA family - - - - - - - - - - - - AsmA k141_10839_1 1122201.AUAZ01000027_gene2168 1.05e-40 149.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the GcvT family soxA - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_10839_2 1208321.D104_01935 7.34e-63 193.0 COG4311@1|root,COG4311@2|Bacteria,1MZC3@1224|Proteobacteria,1S6M7@1236|Gammaproteobacteria,1XK1T@135619|Oceanospirillales 135619|Oceanospirillales E Sarcosine oxidase, delta subunit soxD - 1.5.3.1 ko:K00304 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxD k141_10839_3 1278309.KB907099_gene2673 7.78e-97 291.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,1XIN0@135619|Oceanospirillales 135619|Oceanospirillales E Sarcosine oxidase, subunit beta - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO k141_10092_1 1049564.TevJSym_ai00970 9.88e-10 59.7 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1J53A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475 ACT_4,HD_4,RelA_SpoT,TGS k141_10092_2 1249627.D779_0944 8.89e-65 199.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales 135613|Chromatiales J PFAM Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP k141_10092_3 1117319.PSPO_11742 5.48e-10 58.9 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,2Q14R@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_13588_1 317025.Tcr_0338 1.38e-125 370.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria,462ZC@72273|Thiotrichales 72273|Thiotrichales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_12925_1 1283300.ATXB01000001_gene1476 1.44e-54 183.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XE02@135618|Methylococcales 135618|Methylococcales M TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_16344_1 1278309.KB907102_gene26 3.65e-94 290.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XI59@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_21984_1 105559.Nwat_0029 2.4e-87 273.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales 135613|Chromatiales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_3837_1 572477.Alvin_0225 3.47e-50 171.0 COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,1S2XS@1236|Gammaproteobacteria,1WYBW@135613|Chromatiales 135613|Chromatiales M Polysaccharide biosynthesis protein - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_3837_2 439235.Dalk_1656 9.12e-47 161.0 COG0451@1|root,COG0451@2|Bacteria,1MW8N@1224|Proteobacteria,42NWD@68525|delta/epsilon subdivisions,2WIM8@28221|Deltaproteobacteria,2MJ2N@213118|Desulfobacterales 28221|Deltaproteobacteria GM NAD dependent epimerase/dehydratase family - - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k141_11516_1 521000.PROVRETT_05615 2.97e-19 79.0 COG0401@1|root,COG0401@2|Bacteria,1N9JZ@1224|Proteobacteria,1SCHH@1236|Gammaproteobacteria,3Z9GV@586|Providencia 1236|Gammaproteobacteria S Proteolipid membrane potential modulator - - - - - - - - - - - - Pmp3 k141_11516_2 1278309.KB907105_gene1472 2.15e-50 160.0 2E0WD@1|root,32WDD@2|Bacteria,1N1Y0@1224|Proteobacteria,1S9P9@1236|Gammaproteobacteria,1XKVT@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11516_3 1278309.KB907105_gene1474 1.79e-18 76.3 2DC7D@1|root,2ZD5G@2|Bacteria,1PAIM@1224|Proteobacteria,1SV8B@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11516_4 1278309.KB907105_gene1476 1.59e-110 319.0 COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,1S26Z@1236|Gammaproteobacteria,1XIQB@135619|Oceanospirillales 135619|Oceanospirillales S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k141_11516_5 1278309.KB907105_gene1477 7.38e-94 278.0 COG1309@1|root,COG1309@2|Bacteria,1RHF5@1224|Proteobacteria,1S8K9@1236|Gammaproteobacteria,1XR1H@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_11516_7 748658.KB907327_gene1077 7.43e-32 132.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S5H1@1236|Gammaproteobacteria 1236|Gammaproteobacteria T (GGDEF) domain - - - - - - - - - - - - GGDEF,PAS,PAS_8,PAS_9 k141_11516_8 1278309.KB907105_gene1479 8.91e-156 444.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1XINY@135619|Oceanospirillales 135619|Oceanospirillales O COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - - - - - - - - - - Band_7,Band_7_C k141_11516_9 1278309.KB907105_gene1480 3.85e-75 228.0 COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,1S5W4@1236|Gammaproteobacteria,1XKEJ@135619|Oceanospirillales 135619|Oceanospirillales OU NfeD-like C-terminal, partner-binding - - - ko:K07340 - - - - ko00000 - - - NfeD k141_11516_10 28229.ND2E_0024 7.56e-69 221.0 COG3219@1|root,COG3219@2|Bacteria,1MZS2@1224|Proteobacteria,1S9N6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 k141_11516_11 392500.Swoo_4062 1.03e-147 423.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,2QA0E@267890|Shewanellaceae 1236|Gammaproteobacteria S Xylose isomerase domain protein TIM barrel - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_12232_1 411154.GFO_2845 1.61e-31 126.0 COG0388@1|root,COG0388@2|Bacteria,4PMRR@976|Bacteroidetes,1IJXU@117743|Flavobacteriia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB k141_3188_1 582744.Msip34_1308 6.22e-90 277.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria 28216|Betaproteobacteria K PFAM regulatory protein, MerR - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 k141_19856_1 522306.CAP2UW1_3099 5.31e-09 55.5 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,2VWZ9@28216|Betaproteobacteria 28216|Betaproteobacteria S Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C k141_19856_2 396588.Tgr7_3151 8.14e-54 172.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales 135613|Chromatiales K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_370_1 1232683.ADIMK_0818 2.08e-105 318.0 COG1262@1|root,COG1262@2|Bacteria,1R21A@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1566) - - - - - - - - - - - - DUF1566 k141_17068_1 1288826.MSNKSG1_14622 3.3e-250 695.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,46553@72275|Alteromonadaceae 1236|Gammaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_17068_2 1288826.MSNKSG1_14617 0.0 868.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,46440@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_17068_3 1288826.MSNKSG1_14612 8e-172 480.0 COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,1S22P@1236|Gammaproteobacteria,465K4@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 k141_17068_4 1288826.MSNKSG1_14607 1.38e-150 424.0 COG0398@1|root,COG0398@2|Bacteria,1RDYV@1224|Proteobacteria,1SA20@1236|Gammaproteobacteria,46BBJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_17068_5 1288826.MSNKSG1_14602 4.47e-27 108.0 COG1807@1|root,COG1807@2|Bacteria,1MXH5@1224|Proteobacteria,1RSQE@1236|Gammaproteobacteria,464KM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_10840_1 1129794.C427_2830 3.06e-107 343.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,464K7@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_21306_1 269799.Gmet_1130 1.62e-55 184.0 2AAD4@1|root,314QZ@2|Bacteria,1PUJK@1224|Proteobacteria,437DR@68525|delta/epsilon subdivisions,2XA1Q@28221|Deltaproteobacteria,43VSN@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_5221_1 1134474.O59_004078 7.06e-162 473.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type VI secretion vasA - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k141_6588_1 768671.ThimaDRAFT_2884 5.24e-255 736.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1WXN6@135613|Chromatiales 135613|Chromatiales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_14977_1 1123514.KB905899_gene842 5.21e-142 425.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_13590_1 1123009.AUID01000014_gene1787 1.66e-92 286.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,268H8@186813|unclassified Clostridiales 186801|Clostridia P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_4562_1 1288826.MSNKSG1_07943 4.67e-52 170.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,465QN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_4562_2 1288826.MSNKSG1_07948 0.0 1847.0 COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,465V1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zn-dependent peptidases, insulinase-like - - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C k141_4562_3 1479237.JMLY01000001_gene2817 1.58e-88 262.0 2DVIK@1|root,33W2C@2|Bacteria,1NWVD@1224|Proteobacteria,1SNXI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4562_4 1288826.MSNKSG1_07958 4.17e-118 350.0 COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,1SYQP@1236|Gammaproteobacteria,46BIB@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - MORN,PEGA k141_16345_1 396588.Tgr7_2686 2.08e-47 158.0 COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,1SA1H@1236|Gammaproteobacteria,1X12H@135613|Chromatiales 135613|Chromatiales T Cyclic nucleotide-binding domain - - - - - - - - - - - - cNMP_binding k141_18463_1 870187.Thini_1173 7.08e-159 449.0 COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T3U6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family - - 2.1.1.156 ko:K18896 ko00260,map00260 - R10060 RC00003,RC03038 ko00000,ko00001,ko01000 - - - Methyltransf_25 k141_15710_1 1042375.AFPL01000019_gene220 2.31e-89 278.0 COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,1SDSA@1236|Gammaproteobacteria,4694W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pfam:AmoA - - - ko:K07120 - - - - ko00000 - - - AbrB k141_15710_2 491952.Mar181_3510 1.5e-22 97.4 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XHN7@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctA - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_8099_1 991905.SL003B_2333 2.54e-94 298.0 COG0243@1|root,COG0243@2|Bacteria,1MX0A@1224|Proteobacteria,2TRN3@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family aoxB - 1.20.2.1,1.20.9.1 ko:K08356 - - - - ko00000,ko01000,ko02000 5.A.3.6 - - Molybdopterin,Molydop_binding k141_10841_1 1123393.KB891316_gene1314 3.16e-101 303.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,2VPIS@28216|Betaproteobacteria,1KSVS@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_17802_2 1049564.TevJSym_be00280 1.09e-81 259.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1J55B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_2885 Glu_cys_ligase k141_12926_1 1121447.JONL01000001_gene603 6.73e-45 173.0 COG0642@1|root,COG2114@1|root,COG2114@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - 2.7.13.3 ko:K07648 ko02020,ko02026,map02020,map02026 M00456 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HWE_HK,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k141_21986_1 349124.Hhal_1107 4.16e-66 218.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1X0BN@135613|Chromatiales 135613|Chromatiales G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_10093_1 472759.Nhal_3150 3.86e-40 139.0 COG0569@1|root,COG0569@2|Bacteria,1RDDX@1224|Proteobacteria,1S3ZR@1236|Gammaproteobacteria,1WY9A@135613|Chromatiales 135613|Chromatiales C TrkA-N domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_10093_2 1167006.UWK_00969 7.42e-117 358.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2MJ0H@213118|Desulfobacterales 28221|Deltaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_17070_1 713586.KB900536_gene1097 4.21e-44 155.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1WWUV@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_19224_1 1123401.JHYQ01000022_gene1141 9.85e-12 64.3 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG0671 Membrane-associated phospholipid phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 k141_12233_1 314278.NB231_09098 5.57e-12 65.9 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1WWUF@135613|Chromatiales 135613|Chromatiales S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin k141_12233_2 713586.KB900536_gene274 3.19e-107 315.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_12233_3 215803.DB30_3350 4.13e-14 70.5 COG2265@1|root,COG2265@2|Bacteria,1QV4X@1224|Proteobacteria,43BZ1@68525|delta/epsilon subdivisions 1224|Proteobacteria J Thiopurine S-methyltransferase (TPMT) tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_15711_1 857087.Metme_1838 2.26e-38 132.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XFB3@135618|Methylococcales 135618|Methylococcales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid - - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_15711_2 1335757.SPICUR_05325 8.25e-09 58.9 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1RY9Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_373_1 314271.RB2654_21418 2.5e-35 126.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2TTWH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MA20_24385 - - - - - - - - - - - adh_short k141_373_2 633131.TR2A62_1875 2.81e-26 108.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2TS0Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - - - - - - - - - - HAD,UbiA k141_5249_1 62928.azo2556 3.43e-16 89.0 COG0689@1|root,COG2304@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG0689@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QU09@1224|Proteobacteria 1224|Proteobacteria M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - Calx-beta,DUF4347,He_PIG,VWA_2 k141_5249_2 748280.NH8B_2664 1.24e-12 70.9 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2VIES@28216|Betaproteobacteria 28216|Betaproteobacteria M COG0845 Membrane-fusion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_21999_1 1049564.TevJSym_ar00370 8.06e-43 152.0 COG1142@1|root,COG1142@2|Bacteria,1RIXA@1224|Proteobacteria,1SBMD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - - k141_21999_2 87626.PTD2_06454 5.94e-27 108.0 COG1246@1|root,COG1246@2|Bacteria,1QVUT@1224|Proteobacteria,1T2JM@1236|Gammaproteobacteria,2Q5GJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C k141_19873_1 1121935.AQXX01000106_gene567 2.02e-90 270.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XH6V@135619|Oceanospirillales 135619|Oceanospirillales D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran k141_16365_1 925409.KI911562_gene526 2.13e-90 276.0 COG3507@1|root,COG3507@2|Bacteria,4NIFE@976|Bacteroidetes,1IWZ0@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 43 family - - - - - - - - - - - - CBM_6,Glyco_hydro_43 k141_12953_1 1280001.BAOA01000019_gene460 1.84e-37 138.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XVD6@135623|Vibrionales 135623|Vibrionales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_4574_1 177437.HRM2_24810 5.26e-23 103.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales 28221|Deltaproteobacteria L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_13619_1 322710.Avin_01450 1.23e-134 394.0 COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the NifD NifK NifE NifN family nifE - - ko:K02587 - - - - ko00000 - - - Oxidored_nitro k141_3848_1 1026882.MAMP_02816 1.87e-116 351.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales 72273|Thiotrichales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_6604_1 1237149.C900_02622 3.09e-107 321.0 COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,47JDY@768503|Cytophagia 976|Bacteroidetes C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bfmBB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_12413_1 1056820.KB900638_gene123 9.38e-23 97.4 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,2PN4R@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Threonyl and Alanyl tRNA synthetase second additional domain thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_7491_1 985054.JQEZ01000003_gene1407 2.27e-111 333.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,4NB4K@97050|Ruegeria 28211|Alphaproteobacteria H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M k141_22110_1 1049564.TevJSym_bv00110 5.18e-72 236.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1J5PE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_2579_1 1121904.ARBP01000053_gene483 3.3e-113 346.0 COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia 976|Bacteroidetes P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_6049_1 1217713.F993_01675 4.64e-50 166.0 28J2E@1|root,2Z8YX@2|Bacteria,1REPW@1224|Proteobacteria,1S4IX@1236|Gammaproteobacteria,3NQXK@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k141_21452_1 1278309.KB907100_gene2012 1.79e-223 623.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,1RPAT@1236|Gammaproteobacteria,1XHZS@135619|Oceanospirillales 135619|Oceanospirillales EGP Major facilitator - - - ko:K08224 - - - - ko00000,ko02000 2.A.1.36 - - MFS_1 k141_21452_2 1278309.KB907100_gene2013 3.83e-160 454.0 COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,1RNYQ@1236|Gammaproteobacteria,1XIVT@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_21452_3 1278309.KB907100_gene2014 3.32e-55 172.0 COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,1XKQS@135619|Oceanospirillales 135619|Oceanospirillales S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions ppnP - 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 - R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 - - - DUF1255 k141_21452_4 1278309.KB907100_gene2015 1.38e-274 753.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1XHIW@135619|Oceanospirillales 135619|Oceanospirillales EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_21452_5 1278309.KB907100_gene2016 3.12e-192 538.0 COG2267@1|root,COG2267@2|Bacteria,1RAQZ@1224|Proteobacteria,1S2YX@1236|Gammaproteobacteria,1XJ98@135619|Oceanospirillales 135619|Oceanospirillales I COG2267 Lysophospholipase - - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 k141_21452_6 1278309.KB907100_gene2017 3.23e-117 370.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XHS8@135619|Oceanospirillales 135619|Oceanospirillales DM COG3264 Small-conductance mechanosensitive channel - - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - MS_channel,MscS_TM,MscS_porin k141_4724_2 1121015.N789_06265 1.11e-47 159.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1X304@135614|Xanthomonadales 135614|Xanthomonadales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k141_11662_1 292415.Tbd_2662 5.25e-90 277.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KRAF@119069|Hydrogenophilales 119069|Hydrogenophilales F ATP-grasp domain - - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_15871_1 1278309.KB907100_gene2020 0.0 955.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_1915_1 1278309.KB907101_gene322 3.09e-121 358.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XIMN@135619|Oceanospirillales 135619|Oceanospirillales MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_1915_2 1278309.KB907101_gene323 1.05e-255 730.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH4Q@135619|Oceanospirillales 135619|Oceanospirillales V efflux pump - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_16527_1 1122599.AUGR01000005_gene1939 8.82e-77 237.0 COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1S85J@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Branched-chain amino acid permease - - - - - - - - - - - - AzlC k141_16527_2 301.JNHE01000008_gene3761 2.39e-236 657.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RPU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_16527_3 301.JNHE01000008_gene3762 2.13e-63 199.0 COG3090@1|root,COG3090@2|Bacteria,1RA9W@1224|Proteobacteria,1S210@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_16527_4 301.JNHE01000008_gene3763 4.53e-22 91.7 COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1S03A@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP k141_3326_1 1049564.TevJSym_ai00340 6.58e-69 231.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1J534@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_22111_1 1144325.PMI22_04524 1.6e-24 106.0 COG2199@1|root,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,HDOD,Response_reg k141_17984_1 1442599.JAAN01000005_gene951 3.84e-90 278.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1X3WE@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_7492_1 868131.MSWAN_1360 1.01e-46 164.0 COG2089@1|root,arCOG01050@2157|Archaea,2XTT7@28890|Euryarchaeota 28890|Euryarchaeota M PFAM N-acetylneuraminic acid synthase - - 2.5.1.101 ko:K18430 ko00520,map00520 - R10304 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k141_1250_1 388739.RSK20926_16207 9.58e-34 127.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TQVS@28211|Alphaproteobacteria,2P1PF@2433|Roseobacter 28211|Alphaproteobacteria H pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - - - - - - - - - - DegT_DnrJ_EryC1 k141_1250_2 195105.CN97_03050 1.34e-05 44.7 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 k141_10995_1 391626.OAN307_c39120 1.33e-146 431.0 COG1653@1|root,COG1653@2|Bacteria,1N1NW@1224|Proteobacteria,2U094@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 k141_15878_4 207954.MED92_02651 2.15e-17 79.0 COG1309@1|root,COG1309@2|Bacteria,1NM93@1224|Proteobacteria,1S56I@1236|Gammaproteobacteria,1XP5A@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_3976_1 472759.Nhal_0507 5.86e-60 195.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1WWM5@135613|Chromatiales 135613|Chromatiales OU PFAM peptidase S49 - - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_11668_1 1288826.MSNKSG1_11743 3.7e-27 102.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,466V2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_11668_2 1288826.MSNKSG1_11738 2.04e-65 199.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,467SC@72275|Alteromonadaceae 1236|Gammaproteobacteria J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_11668_3 1288826.MSNKSG1_11733 2.59e-141 400.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,464RW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_11668_4 1288826.MSNKSG1_11728 0.0 1207.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,464T9@72275|Alteromonadaceae 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_11668_5 1288826.MSNKSG1_11723 2.64e-180 504.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,4642K@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind k141_11668_6 1288826.MSNKSG1_11718 2.51e-314 857.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,464J6@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_11668_7 1288826.MSNKSG1_11713 4.07e-154 435.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,466HI@72275|Alteromonadaceae 1236|Gammaproteobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1,5.3.1.33 ko:K01803,ko:K21910 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_11668_8 1288826.MSNKSG1_11708 4.49e-70 213.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,467VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Preprotein translocase subunit SecG secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_11668_9 1288826.MSNKSG1_11703 1.15e-106 307.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,4677T@72275|Alteromonadaceae 1236|Gammaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_11668_10 1288826.MSNKSG1_11698 0.0 910.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,4648A@72275|Alteromonadaceae 1236|Gammaproteobacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_11668_11 1288826.MSNKSG1_11693 0.0 1111.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_13113_1 279714.FuraDRAFT_2740 2.4e-23 106.0 COG2199@1|root,COG2199@2|Bacteria,1RDM8@1224|Proteobacteria,2VRUB@28216|Betaproteobacteria,2KSVV@206351|Neisseriales 206351|Neisseriales T diguanylate cyclase - - - - - - - - - - - - CHASE,GGDEF k141_545_1 103733.JNYO01000022_gene6881 1.04e-38 155.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_2593_1 745411.B3C1_06959 2.23e-28 110.0 COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1J5TS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG1192 ATPases involved in chromosome partitioning XCC1889 - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_6079_1 748247.AZKH_1658 9.88e-67 229.0 COG1196@1|root,COG1352@1|root,COG2201@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2WGKT@28216|Betaproteobacteria,2KZYT@206389|Rhodocyclales 206389|Rhodocyclales DNT PAS domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,PAS_10 k141_18650_2 292415.Tbd_1253 3.9e-98 290.0 COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,2WE8S@28216|Betaproteobacteria,1KSAI@119069|Hydrogenophilales 119069|Hydrogenophilales S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_17241_1 519989.ECTPHS_01684 1.22e-87 264.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1WW0D@135613|Chromatiales 135613|Chromatiales S PFAM ABC transporter - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_14398_1 1278309.KB907099_gene2679 1.2e-133 391.0 COG4977@1|root,COG4977@2|Bacteria,1RC9C@1224|Proteobacteria,1RYDT@1236|Gammaproteobacteria,1XJA4@135619|Oceanospirillales 135619|Oceanospirillales K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_1266_1 1288826.MSNKSG1_10083 1.48e-43 142.0 COG0298@1|root,COG0298@2|Bacteria 2|Bacteria O carbon dioxide binding hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC k141_1266_2 1288826.MSNKSG1_10078 2.2e-252 694.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,466NH@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the HypD family hypD - - ko:K04654 - - - - ko00000 - - - HypD k141_1266_3 1288826.MSNKSG1_10073 7.66e-217 602.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,466ND@72275|Alteromonadaceae 1236|Gammaproteobacteria O AIR synthase related protein, N-terminal domain hypE GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_1266_4 1288826.MSNKSG1_10068 4.96e-141 401.0 28TMI@1|root,30GG2@2|Bacteria,1RE0D@1224|Proteobacteria,1S0JA@1236|Gammaproteobacteria,467PB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Spond_N k141_1266_5 1288826.MSNKSG1_10063 9.95e-149 420.0 28TMI@1|root,2ZFV4@2|Bacteria,1R9YK@1224|Proteobacteria,1S221@1236|Gammaproteobacteria,466IE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Spondin_N - - - - - - - - - - - - Spond_N k141_1266_6 1288826.MSNKSG1_10058 7.19e-44 152.0 COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,1RYVT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive Ion channel - - - - - - - - - - - - MS_channel k141_13114_1 1123405.AUMM01000022_gene1890 5.49e-16 80.5 COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,4HC2H@91061|Bacilli 91061|Bacilli L ATP-binding protein - - - - - - - - - - - - IstB_IS21 k141_10285_1 1121935.AQXX01000143_gene4135 6.85e-06 46.2 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,1S63W@1236|Gammaproteobacteria,1XMRJ@135619|Oceanospirillales 135619|Oceanospirillales S Cupin domain - - - - - - - - - - - - Cupin_2 k141_10285_2 1208321.D104_02300 4.4e-99 295.0 COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,1S1VI@1236|Gammaproteobacteria,1XRQ0@135619|Oceanospirillales 135619|Oceanospirillales Q dienelactone hydrolase - - - - - - - - - - - - DLH k141_10285_3 1535422.ND16A_2338 1.12e-19 84.7 COG2105@1|root,COG2105@2|Bacteria,1RHE8@1224|Proteobacteria,1S708@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AIG2-like family - - - - - - - - - - - - AIG2_2,GGACT k141_15879_1 396588.Tgr7_2778 1.78e-142 440.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_22134_1 1049564.TevJSym_ab00410 1.01e-97 304.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1J50Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,STAS_2,Sulfate_transp k141_22134_2 765912.Thimo_0821 3.2e-11 70.1 COG0790@1|root,COG0790@2|Bacteria,1QCXZ@1224|Proteobacteria,1TKB7@1236|Gammaproteobacteria,1X1ES@135613|Chromatiales 135613|Chromatiales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_8841_1 1249627.D779_2184 1.52e-58 188.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales 135613|Chromatiales I PFAM CDP-alcohol phosphatidyltransferase - - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf k141_8841_2 105559.Nwat_1839 1.48e-31 125.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2066) - - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_9517_1 1288494.EBAPG3_2300 1.39e-54 181.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,3733V@32003|Nitrosomonadales 28216|Betaproteobacteria O AIR synthase related protein, N-terminal domain - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_18651_1 2340.JV46_28090 1.36e-90 279.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1J4E8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG0348 Polyferredoxin ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_21477_1 290397.Adeh_2440 3.9e-10 61.6 COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales 28221|Deltaproteobacteria F ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4 k141_6080_1 574966.KB898655_gene1585 8.42e-88 278.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1XHHF@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N k141_17242_1 520999.PROVALCAL_03425 2.43e-32 120.0 COG3728@1|root,COG3728@2|Bacteria,1RG2M@1224|Proteobacteria,1S5U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria L terminase, small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k141_20718_1 105559.Nwat_2327 1.7e-107 323.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1X07Y@135613|Chromatiales 135613|Chromatiales E TIGRFAM amidase, hydantoinase carbamoylase - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_20718_2 1158182.KB905024_gene138 9.47e-21 90.1 2EK1K@1|root,33DS2@2|Bacteria,1NI6I@1224|Proteobacteria,1SH8F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14399_1 768671.ThimaDRAFT_1655 1.1e-30 115.0 COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales 135613|Chromatiales Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_25 k141_1267_1 754477.Q7C_1249 2.63e-77 246.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,460CV@72273|Thiotrichales 72273|Thiotrichales G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_11016_1 1278309.KB907100_gene2353 0.0 1378.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales 135619|Oceanospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_11016_2 1278309.KB907100_gene2354 1.03e-126 363.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XJCE@135619|Oceanospirillales 135619|Oceanospirillales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_11016_3 1278309.KB907100_gene2355 8.5e-116 334.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_11016_4 1278309.KB907100_gene2356 4.62e-117 338.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XJFN@135619|Oceanospirillales 135619|Oceanospirillales O Thiol disulfide interchange protein dsbA - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA k141_11016_5 1278309.KB907100_gene2357 1.59e-221 628.0 COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,1XIYN@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF k141_11016_6 1278309.KB907100_gene2358 0.0 962.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XICK@135619|Oceanospirillales 135619|Oceanospirillales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_11016_7 1226994.AMZB01000122_gene2712 1.65e-69 212.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1YFSV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH k141_11016_8 1278309.KB907100_gene2360 7.4e-58 181.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1XKTK@135619|Oceanospirillales 135619|Oceanospirillales E Phosphoribosyl-ATP hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH k141_11016_9 999141.GME_18103 2.91e-07 51.2 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XM7C@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_11016_10 948565.AFFP02000011_gene1850 1.55e-12 68.6 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1Y8RY@135625|Pasteurellales 135625|Pasteurellales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - - k141_11016_11 1278309.KB907100_gene2363 1.44e-45 154.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1XH5S@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_19374_1 857087.Metme_3504 5.26e-92 284.0 COG3211@1|root,COG3211@2|Bacteria,1R690@1224|Proteobacteria 2|Bacteria S Bacterial protein of unknown function (DUF839) phoX - - ko:K07093 - - - - ko00000 - - - DUF839,Metallophos,Pur_ac_phosph_N k141_1936_1 1278309.KB907100_gene1994 5.19e-225 639.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XHZK@135619|Oceanospirillales 135619|Oceanospirillales U Type II and III secretion system protein pilQ - - ko:K02507,ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N k141_3977_1 1122599.AUGR01000002_gene3358 1.45e-138 406.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XNV7@135619|Oceanospirillales 135619|Oceanospirillales P Na+/H+ antiporter 1 - - - - - - - - - - - - Na_H_antiport_1 k141_546_2 349521.HCH_01358 7.56e-70 214.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1XJKM@135619|Oceanospirillales 135619|Oceanospirillales J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_6860_1 28258.KP05_10510 1.03e-80 245.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XH4S@135619|Oceanospirillales 135619|Oceanospirillales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 k141_6860_2 59538.XP_005976936.1 6.43e-06 48.5 COG0147@1|root,KOG1223@2759|Eukaryota,38FJ5@33154|Opisthokonta 33154|Opisthokonta E anthranilate synthase activity TRP2 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_14608_1 272942.RCAP_rcc02668 1.07e-78 246.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TQYV@28211|Alphaproteobacteria,1FBDF@1060|Rhodobacter 28211|Alphaproteobacteria H Belongs to the beta-ketoacyl-ACP synthases family fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_14608_2 367336.OM2255_10985 0.000227 42.4 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_2085_2 765913.ThidrDRAFT_2619 2.28e-50 166.0 COG3439@1|root,COG3439@2|Bacteria,1RA8I@1224|Proteobacteria,1S34D@1236|Gammaproteobacteria,1WXZJ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_20097_1 1535422.ND16A_2695 2.88e-67 219.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,2Q61P@267889|Colwelliaceae 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim k141_14609_1 1283300.ATXB01000001_gene879 9.65e-15 76.3 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XEBN@135618|Methylococcales 135618|Methylococcales NU COG3170 Tfp pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - k141_20881_1 435908.IDSA_06025 9.46e-65 204.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,2QG10@267893|Idiomarinaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1415) - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_20881_2 396588.Tgr7_2695 1.85e-54 188.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales 135613|Chromatiales T PFAM Metal-dependent hydrolase HDOD - - - - - - - - - - - - HDOD,bPH_2 k141_15255_1 1278309.KB907108_gene1630 1.3e-155 440.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,1XI1D@135619|Oceanospirillales 135619|Oceanospirillales P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_9700_1 76114.ebA3998 2.61e-100 303.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales 206389|Rhodocyclales M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_9700_3 314230.DSM3645_17660 1.53e-06 50.1 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2IY6V@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k141_20882_1 1202962.KB907170_gene2408 7.85e-10 58.9 2EUFJ@1|root,33MXU@2|Bacteria,1NZHB@1224|Proteobacteria,1SQC7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LPP20 lipoprotein - - - - - - - - - - - - LPP20 k141_20882_2 926550.CLDAP_01910 4.01e-36 139.0 COG1067@1|root,COG1067@2|Bacteria,2G64R@200795|Chloroflexi 200795|Chloroflexi O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_20099_1 472759.Nhal_0308 5.39e-77 242.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X29C@135613|Chromatiales 135613|Chromatiales I Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_20883_1 748247.AZKH_4193 4.39e-17 85.1 COG0840@1|root,COG0840@2|Bacteria,1NCMF@1224|Proteobacteria,2VJC0@28216|Betaproteobacteria,2KW4V@206389|Rhodocyclales 206389|Rhodocyclales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_20883_2 1453503.AU05_11840 5.22e-28 103.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S4NM@1236|Gammaproteobacteria,1YKPH@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KT cheY-homologous receiver domain - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_9701_1 1278309.KB907105_gene1492 9.62e-89 284.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XH2S@135619|Oceanospirillales 135619|Oceanospirillales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_2086_1 598659.NAMH_1298 1.53e-45 162.0 COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria ET Diguanylate cyclase - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - GGDEF,NMT1,SBP_bac_3 k141_2086_2 1278309.KB907108_gene1632 1.42e-109 319.0 COG1280@1|root,COG1280@2|Bacteria,1RAI3@1224|Proteobacteria,1S2GP@1236|Gammaproteobacteria,1XJ9E@135619|Oceanospirillales 135619|Oceanospirillales E threonine efflux protein - - - - - - - - - - - - LysE k141_2086_3 1278309.KB907108_gene1633 3.22e-52 176.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1XI84@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG - 2.1.1.174 ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_14610_1 1122599.AUGR01000002_gene3512 6.46e-216 633.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales 135619|Oceanospirillales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_14610_2 344747.PM8797T_15536 1.63e-73 231.0 COG0569@1|root,COG0569@2|Bacteria 2|Bacteria P domain protein - - - - - - - - - - - - TrkA_C k141_14610_3 1038867.AXAY01000007_gene6073 6.57e-34 128.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,3JRV7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family MA20_14610 - - - - - - - - - - - HTH_1,LysR_substrate k141_20100_2 1122939.ATUD01000003_gene3523 2.05e-23 98.6 COG4635@1|root,COG4635@2|Bacteria,2INN9@201174|Actinobacteria,4CTGJ@84995|Rubrobacteria 84995|Rubrobacteria CH Flavodoxin domain - - - - - - - - - - - - Flavodoxin_5 k141_20885_1 990285.RGCCGE502_16600 9.62e-13 72.0 COG1802@1|root,COG1802@2|Bacteria,1PG43@1224|Proteobacteria,2V804@28211|Alphaproteobacteria,4BCEE@82115|Rhizobiaceae 28211|Alphaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR k141_20885_2 1121878.AUGL01000005_gene2587 6.23e-57 190.0 28P7P@1|root,2ZC1Y@2|Bacteria,1RBDI@1224|Proteobacteria,1S2AW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S outer membrane porin, OprD family - - - - - - - - - - - - OprD k141_15256_1 1278309.KB907101_gene736 1.31e-255 703.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1XIGD@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k141_15256_2 440512.C211_12672 1.08e-16 79.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) ygfF - - - - - - - - - - - adh_short_C2 k141_6861_2 1288826.MSNKSG1_16041 0.0 933.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria 1236|Gammaproteobacteria EI Biotin carboxylase pycA - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_6861_3 1288826.MSNKSG1_16036 1.31e-139 394.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,467TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0517 FOG CBS domain - - - - - - - - - - - - CBS k141_6861_5 1288826.MSNKSG1_16026 1.81e-115 343.0 2E9Q2@1|root,333WE@2|Bacteria,1N872@1224|Proteobacteria,1SDWG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14611_1 580332.Slit_2126 2.21e-145 426.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,44V3P@713636|Nitrosomonadales 1224|Proteobacteria H Belongs to the alpha-IPM synthase homocitrate synthase family leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_20887_1 420662.Mpe_A3012 3.19e-76 239.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2VHU3@28216|Betaproteobacteria,1KJ8D@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 k141_15257_1 1234364.AMSF01000025_gene3594 5.86e-109 323.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1X5IH@135614|Xanthomonadales 135614|Xanthomonadales G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_14612_1 697282.Mettu_3162 1.33e-51 186.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_2089_2 1049564.TevJSym_av00470 3.87e-46 160.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1J4M8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_20889_1 756067.MicvaDRAFT_4927 7.44e-18 90.1 COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales 1117|Cyanobacteria KLT Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg k141_20103_1 1117647.M5M_07080 2.87e-34 125.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1J5SC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k141_14613_1 1286106.MPL1_05404 2.28e-47 170.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales 72273|Thiotrichales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_14613_2 713586.KB900536_gene2642 4.11e-42 150.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k141_20890_1 498211.CJA_2945 3.06e-28 117.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1FGTM@10|Cellvibrio 1236|Gammaproteobacteria NT Signal transducing histidine kinase, homodimeric domain cheA3 - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_15258_1 927658.AJUM01000022_gene1096 8.13e-120 365.0 COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes 976|Bacteroidetes P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_6862_1 1232410.KI421425_gene1546 1.15e-77 237.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,43TGA@69541|Desulfuromonadales 28221|Deltaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_6862_2 1279017.AQYJ01000026_gene63 8.4e-26 99.0 2EQ5T@1|root,33HS3@2|Bacteria,1NMTN@1224|Proteobacteria,1SIGB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6862_3 1279017.AQYJ01000026_gene64 6.34e-55 180.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,4697B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_12,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_8 k141_6862_4 1042377.AFPJ01000023_gene664 6.32e-71 243.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_20104_1 765912.Thimo_3559 2.65e-15 74.3 28JAR@1|root,2Z95M@2|Bacteria,1RGE3@1224|Proteobacteria,1S5F4@1236|Gammaproteobacteria,1WZSN@135613|Chromatiales 135613|Chromatiales S YfdX protein - - - - - - - - - - - - YfdX k141_20104_2 1125973.JNLC01000014_gene2525 1.5e-45 155.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,3JT22@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T transcriptional regulator, winged helix family ragA GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_20891_1 395963.Bind_3523 2.21e-23 97.8 COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria,3NCAQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria K PFAM regulatory protein GntR HTH - - - ko:K11475 - - - - ko00000,ko03000 - - - FCD,GntR k141_20891_2 1238182.C882_4548 3.76e-35 135.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JQI2@204441|Rhodospirillales 204441|Rhodospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_15259_2 640081.Dsui_3445 5.98e-30 120.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VN72@28216|Betaproteobacteria,2KU7A@206389|Rhodocyclales 206389|Rhodocyclales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - ko:K00786 - - - - ko00000,ko01000 - - - PMT_2 k141_20892_1 485916.Dtox_1442 1.78e-30 122.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,24FM2@186801|Clostridia 186801|Clostridia L PFAM Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_6865_2 472759.Nhal_3890 4.67e-36 128.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales 135613|Chromatiales NU PFAM Fimbrial assembly - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_15260_1 1500893.JQNB01000001_gene3457 2.05e-98 295.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1X3BT@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the Glu Leu Phe Val dehydrogenases family leu - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N k141_4076_1 1288826.MSNKSG1_07898 2.71e-167 473.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,464VS@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_4076_3 1288826.MSNKSG1_07903 0.0 1264.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,464FV@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_4076_4 1288826.MSNKSG1_07908 6.89e-128 363.0 COG3318@1|root,COG3318@2|Bacteria,1NA8N@1224|Proteobacteria,1SDYK@1236|Gammaproteobacteria,46BT8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0149 family IV02_13620 - - ko:K07039 - - - - ko00000 - - - UPF0149 k141_4076_5 1288826.MSNKSG1_07913 6.25e-203 562.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,466MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S metal-dependent phosphoesterases (PHP family) trpH GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_4076_6 1288826.MSNKSG1_07918 3.59e-64 196.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,467T6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05527,ko:K09780 - - - - ko00000,ko03000 - - - YCII k141_4076_7 1288826.MSNKSG1_07923 1.27e-60 194.0 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 k141_14614_1 1288826.MSNKSG1_16271 0.0 1484.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_20893_1 472759.Nhal_0798 2.02e-169 495.0 COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1WWN6@135613|Chromatiales 135613|Chromatiales E Extracellular solute-binding protein, family 5 - - - - - - - - - - - - SBP_bac_5 k141_6867_1 675806.VII_002392 1.11e-79 246.0 COG3181@1|root,COG3181@2|Bacteria,1MWSC@1224|Proteobacteria,1RYGF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_20208_1 1117647.M5M_01745 3.43e-109 331.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1J524@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_20209_1 1046714.AMRX01000006_gene2908 2.42e-122 371.0 COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,466BY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k141_20210_1 998674.ATTE01000001_gene808 7.31e-56 193.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,461JH@72273|Thiotrichales 72273|Thiotrichales S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_21626_1 935548.KI912159_gene677 2.97e-57 194.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria,43GST@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E PFAM Serine dehydratase alpha chain sdaA GO:0003674,GO:0003824,GO:0003941,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_6992_1 1123360.thalar_02906 7.69e-70 223.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S flavoproteins yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like k141_20239_1 983545.Glaag_1240 1.67e-43 151.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,4675N@72275|Alteromonadaceae 1236|Gammaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_13962_1 1417296.U879_01595 1.25e-107 314.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria 28211|Alphaproteobacteria E branched-chain amino acid livF2 - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_13962_2 391595.RLO149_c019300 1.28e-10 60.5 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TUQB@28211|Alphaproteobacteria,2P1T9@2433|Roseobacter 28211|Alphaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component livG1 - - ko:K01995,ko:K11957 ko02010,ko02024,map02010,map02024 M00237,M00322 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 - - ABC_tran,BCA_ABC_TP_C k141_16754_1 666685.R2APBS1_0971 1.13e-93 303.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1X3ME@135614|Xanthomonadales 135614|Xanthomonadales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_5598_1 1124780.ANNU01000056_gene3466 2.15e-81 263.0 COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia 976|Bacteroidetes C Monomeric isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_8388_1 640512.BC1003_1765 5.97e-24 101.0 COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,1K0JV@119060|Burkholderiaceae 28216|Betaproteobacteria H PFAM UbiA prenyltransferase - - - - - - - - - - - - HAD,UbiA k141_1413_3 1163617.SCD_n02038 8.59e-139 409.0 COG0191@1|root,COG0191@2|Bacteria,1R6TC@1224|Proteobacteria,2VMUH@28216|Betaproteobacteria 28216|Betaproteobacteria G ketose-bisphosphate aldolase - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase k141_1413_4 857087.Metme_2066 1.93e-49 167.0 28NH4@1|root,2ZBJ2@2|Bacteria,1N1V3@1224|Proteobacteria,1T0IS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_6993_1 314287.GB2207_02097 1.19e-10 61.2 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1J4QH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_3504_1 935848.JAEN01000004_gene1413 4.72e-65 207.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2PU8J@265|Paracoccus 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_3504_2 83219.PM02_08720 4.74e-45 157.0 COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria,3ZUZY@60136|Sulfitobacter 28211|Alphaproteobacteria J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA k141_11178_1 1123228.AUIH01000026_gene3874 1.06e-62 203.0 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,1XI7I@135619|Oceanospirillales 135619|Oceanospirillales T response regulator - - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_11178_2 748658.KB907312_gene1888 5.65e-27 102.0 COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS,STAS_2 k141_7695_1 666685.R2APBS1_2515 3.55e-98 304.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1X57Q@135614|Xanthomonadales 135614|Xanthomonadales S M61 glycyl aminopeptidase - - - - - - - - - - - - Peptidase_M61 k141_15526_1 1046724.KB889952_gene2066 2.17e-123 365.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1S0X9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Helix-hairpin-helix containing domain VPA1266 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2,Viral_helicase1 k141_1543_2 317025.Tcr_0580 4.57e-87 261.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,45ZRE@72273|Thiotrichales 72273|Thiotrichales O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_126_1 1122134.KB893650_gene1409 1.74e-07 51.6 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1XHFR@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the aspartate-semialdehyde dehydrogenase family asd-1 - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_126_2 160492.XF_1372 1.59e-16 82.4 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1X4MQ@135614|Xanthomonadales 135614|Xanthomonadales NU Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - TPR_19 k141_6411_1 498211.CJA_1760 5.1e-116 352.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1FGXV@10|Cellvibrio 1236|Gammaproteobacteria O Hsp90 protein htpG GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_853_1 857087.Metme_4572 5.8e-68 211.0 COG2214@1|root,COG2214@2|Bacteria,1RCRR@1224|Proteobacteria,1SXVA@1236|Gammaproteobacteria,1XGBW@135618|Methylococcales 135618|Methylococcales O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k141_14108_1 76114.ebA1805 2.35e-18 90.1 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,2KU83@206389|Rhodocyclales 206389|Rhodocyclales M HlyD family secretion protein - - - ko:K12542 - M00330 - - ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 - - Biotin_lipoyl_2,HlyD,HlyD_3 k141_9891_2 1288826.MSNKSG1_13192 2.12e-76 243.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RSD8@1236|Gammaproteobacteria,465FQ@72275|Alteromonadaceae 1236|Gammaproteobacteria NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_3666_1 1278309.KB907102_gene18 2.56e-155 452.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_3666_2 1278309.KB907102_gene19 2.94e-92 275.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XJKB@135619|Oceanospirillales 135619|Oceanospirillales P nucleotidase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_860_1 572477.Alvin_2123 1.08e-13 71.2 COG0317@1|root,COG0460@1|root,COG0317@2|Bacteria,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1WWHB@135613|Chromatiales 135613|Chromatiales E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k141_860_2 870187.Thini_4052 2.39e-53 178.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,4607F@72273|Thiotrichales 72273|Thiotrichales E PFAM Aminotransferase class I and II - - - ko:K14261 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 k141_18999_1 666685.R2APBS1_1247 2.1e-64 221.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1X3K8@135614|Xanthomonadales 135614|Xanthomonadales NU Tfp pilus assembly protein, tip-associated adhesin PilY1 pilY - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_7135_1 1283300.ATXB01000001_gene1757 1.4e-94 284.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XEJI@135618|Methylococcales 135618|Methylococcales L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_10643_1 1380384.JADN01000003_gene781 1.09e-07 53.5 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia 976|Bacteroidetes E gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_10643_2 504487.JCM19302_309 2.27e-34 126.0 COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 k141_21137_1 489825.LYNGBM3L_54390 7.17e-94 305.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1G02W@1117|Cyanobacteria,1H8RM@1150|Oscillatoriales 1117|Cyanobacteria EQ N-methylhydantoinase B acetone carboxylase alpha subunit oplaH - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_5022_1 396588.Tgr7_3074 7.6e-48 160.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_7849_1 1385517.N800_15275 9.71e-57 196.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1X42Y@135614|Xanthomonadales 135614|Xanthomonadales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HHH_5,Helicase_C,RecG_wedge k141_6434_1 931627.MycrhDRAFT_3460 6.53e-59 191.0 COG0667@1|root,COG0667@2|Bacteria,2GKW7@201174|Actinobacteria,236X0@1762|Mycobacteriaceae 201174|Actinobacteria C Aldo/keto reductase family - - 1.1.1.122 ko:K00064 ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120 M00114 R07675,R08926 RC00066,RC00161 ko00000,ko00001,ko00002,ko01000 - - - Aldo_ket_red k141_12014_1 1278309.KB907109_gene3241 1.2e-06 48.9 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XHJZ@135619|Oceanospirillales 135619|Oceanospirillales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_12014_2 1278309.KB907109_gene3240 5.88e-54 169.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1XKH9@135619|Oceanospirillales 135619|Oceanospirillales J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_12014_3 1278309.KB907109_gene3239 7.77e-189 528.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1XH40@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_12014_4 1278309.KB907109_gene3238 3.62e-77 231.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XKKG@135619|Oceanospirillales 135619|Oceanospirillales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_12014_5 1278309.KB907109_gene3237 2.94e-141 422.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XH9T@135619|Oceanospirillales 135619|Oceanospirillales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_2235_2 1144305.PMI02_04518 3.66e-149 442.0 COG3515@1|root,COG3515@2|Bacteria,1NRMK@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k141_2235_3 700598.Niako_2131 3.72e-77 241.0 COG2159@1|root,COG2159@2|Bacteria,4P1VU@976|Bacteroidetes 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_16896_2 1121904.ARBP01000002_gene7178 3.07e-20 90.9 COG0642@1|root,COG2205@2|Bacteria,4NN26@976|Bacteroidetes,47U6C@768503|Cytophagia 976|Bacteroidetes T 7TM diverse intracellular signalling - - - - - - - - - - - - 7TMR-DISM_7TM,HATPase_c,HisKA k141_13426_1 765912.Thimo_1174 4.67e-81 259.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales 135613|Chromatiales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_13426_2 123899.JPQP01000003_gene1419 2.61e-08 54.7 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,3T1X3@506|Alcaligenaceae 28216|Betaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 k141_5775_2 388401.RB2150_14326 1.35e-79 244.0 2DZVM@1|root,32VK6@2|Bacteria,1R6Z3@1224|Proteobacteria,2TVN0@28211|Alphaproteobacteria,3ZHAK@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - DUF1523 k141_12716_1 393595.ABO_0168 0.000377 42.7 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1XIN2@135619|Oceanospirillales 135619|Oceanospirillales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_12716_2 314292.VAS14_03628 4.46e-17 76.3 2DQRN@1|root,338AZ@2|Bacteria,1R3AB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_21754_1 1348635.BBJY01000001_gene2376 1.95e-37 134.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1Y030@135623|Vibrionales 135623|Vibrionales C Rnf-Nqr subunit, membrane protein - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_21754_2 323261.Noc_1196 2.24e-21 87.8 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WZ6P@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0125 (RnfH) family - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_5023_2 558169.AGAV01000018_gene3415 0.000723 45.4 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli 91061|Bacilli M COG1388 FOG LysM repeat cwlS - - ko:K19223,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60 k141_10644_2 1278309.KB907099_gene2816 3.88e-54 170.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1XKPR@135619|Oceanospirillales 135619|Oceanospirillales O peptidylprolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_10644_3 1278309.KB907099_gene2815 3.35e-29 112.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1S2UC@1236|Gammaproteobacteria,1XRRN@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_7137_1 1088721.NSU_2987 1.19e-47 173.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2K0DW@204457|Sphingomonadales 204457|Sphingomonadales G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase k141_16180_1 1288826.MSNKSG1_10233 2.57e-55 180.0 COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,1RPH7@1236|Gammaproteobacteria,46A2D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase hpaD - 1.13.11.15 ko:K00455 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R03303 RC00643 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_04194,iECBD_1354.ECBD_3668,iECB_1328.ECB_04228,iECD_1391.ECD_04228,iECIAI1_1343.ECIAI1_4573,iECO103_1326.ECO103_5134,iECO26_1355.ECO26_5555,iECSE_1348.ECSE_4627,iECUMN_1333.ECUMN_4973,iEKO11_1354.EKO11_3962,iEcHS_1320.EcHS_A4582,iEcolC_1368.EcolC_3704,iSBO_1134.SBO_4410,iSbBS512_1146.SbBS512_E4888 LigB k141_16180_2 1288826.MSNKSG1_10238 3.22e-12 65.1 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,468GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_17585_1 511062.GU3_02915 6.33e-27 109.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1Y3G7@135624|Aeromonadales 135624|Aeromonadales E Peptidase family M3 prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_17585_2 478741.JAFS01000002_gene240 9.09e-37 137.0 COG1043@1|root,COG1043@2|Bacteria,46SQN@74201|Verrucomicrobia,37G0M@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k141_7850_1 1485544.JQKP01000012_gene2160 1.02e-53 184.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,44V20@713636|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 k141_14828_1 1288826.MSNKSG1_14472 7.12e-178 495.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,4659M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0271 (lamB) family ybgL - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_14828_2 1288826.MSNKSG1_14477 1.32e-73 233.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,46AJ0@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the amidase family - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_3667_1 1088868.CIN_21070 1.1e-18 92.0 COG0318@1|root,COG0318@2|Bacteria,1MZZU@1224|Proteobacteria 1224|Proteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C k141_2236_1 697282.Mettu_1547 9.99e-83 259.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XEHZ@135618|Methylococcales 135618|Methylococcales C FAD linked oxidases, C-terminal domain - - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_8532_1 1237149.C900_03200 2.41e-81 268.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_5024_1 436229.JOEH01000008_gene4198 2.03e-07 57.4 COG1940@1|root,COG1940@2|Bacteria,2GMBH@201174|Actinobacteria,2NGYU@228398|Streptacidiphilus 201174|Actinobacteria GK ROK family - - - - - - - - - - - - HTH_IclR,ROK k141_13427_1 1179778.PMM47T1_10917 4.27e-20 97.4 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14829_1 479434.Sthe_0129 7.13e-53 180.0 COG3434@1|root,COG3434@2|Bacteria,2GA08@200795|Chloroflexi,27Y73@189775|Thermomicrobia 189775|Thermomicrobia T Diguanylate phosphodiesterase - - - - - - - - - - - - HDOD k141_15539_1 1288826.MSNKSG1_04416 4.12e-72 221.0 COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,46711@72275|Alteromonadaceae 1236|Gammaproteobacteria P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_15539_2 1288826.MSNKSG1_04411 1.78e-183 513.0 COG0589@1|root,COG0589@2|Bacteria,1N31F@1224|Proteobacteria,1S903@1236|Gammaproteobacteria,46BDD@72275|Alteromonadaceae 1236|Gammaproteobacteria T Universal stress protein - - - - - - - - - - - - Usp k141_15539_3 1288826.MSNKSG1_04406 0.0 1473.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,464FF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase S16 family - - - ko:K04770 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k141_15539_4 1288826.MSNKSG1_04401 8.7e-135 384.0 COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1SAI2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein domain (DUF2202) - - - - - - - - - - - - DUF2202 k141_15539_5 1288826.MSNKSG1_04396 5.37e-216 595.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,464IW@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase yghU - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N k141_15539_6 1288826.MSNKSG1_04391 5.93e-161 450.0 COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria,46502@72275|Alteromonadaceae 1236|Gammaproteobacteria L 3-methyladenine DNA glycosylase IV02_03670 - - - - - - - - - - - Adenine_glyco k141_15539_8 1288826.MSNKSG1_04381 2.44e-133 378.0 COG1999@1|root,COG1999@2|Bacteria,1RKIP@1224|Proteobacteria,1S62T@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_15539_9 1288826.MSNKSG1_04376 1.32e-24 95.1 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,468EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_12717_1 1042375.AFPL01000046_gene1962 5.61e-36 131.0 2DMMP@1|root,32SHG@2|Bacteria,1RM15@1224|Proteobacteria,1SQ5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2964_2 1249627.D779_1317 2.72e-61 189.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1WY87@135613|Chromatiales 135613|Chromatiales O Belongs to the thioredoxin family - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_2964_3 1049564.TevJSym_ao00570 1.2e-195 555.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4U6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C,RhlB k141_861_1 391615.ABSJ01000042_gene2275 6.33e-263 766.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Glutamate synthase domain gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_5025_1 1266998.ATUJ01000001_gene2842 8.02e-26 105.0 COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2PW63@265|Paracoccus 28211|Alphaproteobacteria J Uncharacterized protein family UPF0004 mtaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 k141_5025_2 384765.SIAM614_09278 2.83e-31 115.0 COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,2U7CB@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 k141_2237_1 458817.Shal_2213 3.7e-13 69.3 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,2Q8HH@267890|Shewanellaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b k141_2237_2 396588.Tgr7_2600 3.26e-38 130.0 COG1993@1|root,COG1993@2|Bacteria,1N8TP@1224|Proteobacteria,1SDYH@1236|Gammaproteobacteria,1WZIY@135613|Chromatiales 135613|Chromatiales S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 k141_19002_1 1163617.SCD_n01495 3.76e-13 67.4 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria 28216|Betaproteobacteria C Succinate dehydrogenase hydrophobic membrane anchor protein sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k141_17586_1 1537994.JQFW01000007_gene2881 5.05e-31 112.0 COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,1SCAV@1236|Gammaproteobacteria,46BN9@72275|Alteromonadaceae 1236|Gammaproteobacteria S YCII-related domain - - - ko:K09780 - - - - ko00000 - - - YCII k141_12015_1 1288826.MSNKSG1_07883 1.5e-114 330.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,4674N@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yceF GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_12015_2 1288826.MSNKSG1_07888 1.91e-227 628.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k141_19689_1 1278309.KB907101_gene519 4.05e-113 333.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,1XJ7W@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - SpoIIM k141_19689_2 1278309.KB907101_gene518 2.45e-126 363.0 COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria,1XK0Q@135619|Oceanospirillales 135619|Oceanospirillales S membrane protein domain - - - - - - - - - - - - RDD k141_19689_3 1278309.KB907101_gene517 5.18e-79 249.0 COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,1SZTB@1236|Gammaproteobacteria,1XRNY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8533_1 1056820.KB900637_gene217 7.41e-09 61.2 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,2PNRM@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Tetratricopeptide repeat-like domain yfgM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - - - - - - - - - - TPR_21 k141_1715_1 444875.E3SMH2_9CAUD 5.03e-27 113.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k141_3787_1 1278309.KB907104_gene869 3.55e-76 231.0 COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,1S5NR@1236|Gammaproteobacteria,1XRC7@135619|Oceanospirillales 135619|Oceanospirillales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_17004_1 1283300.ATXB01000001_gene1192 5.31e-38 145.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XG49@135618|Methylococcales 135618|Methylococcales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9 k141_5876_1 1042375.AFPL01000036_gene3087 5.97e-87 262.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,464HP@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG4221 Short-chain alcohol dehydrogenase of VY92_08700 - - - - - - - - - - - adh_short k141_5876_2 1042375.AFPL01000036_gene3086 1.78e-130 377.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,466KY@72275|Alteromonadaceae 1236|Gammaproteobacteria I Enoyl-CoA hydratase/isomerase - GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 4.2.1.17,5.3.3.18 ko:K01692,ko:K15866 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R09837,R09839 RC00004,RC00326,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02689,RC03003 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_5876_3 1042375.AFPL01000036_gene3085 7.62e-150 438.0 COG1012@1|root,COG1012@2|Bacteria,1MY4N@1224|Proteobacteria,1RR7Y@1236|Gammaproteobacteria,4668H@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family paaN - - - - - - - - - - - Aldedh k141_13519_1 1278309.KB907099_gene2531 7.45e-70 232.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_13519_2 1122599.AUGR01000004_gene2200 0.0 909.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XJ1B@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GGDEF,PAS_9 k141_13519_3 1318628.MARLIPOL_02715 9.35e-26 109.0 2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13519_5 207954.MED92_12966 4.83e-24 93.6 COG5453@1|root,COG5453@2|Bacteria 2|Bacteria S Transcriptional activator HlyU R01627 - - - - - - - - - - - HlyU k141_13519_6 1430440.MGMSRv2_3253 1.31e-191 566.0 COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria,2JR3V@204441|Rhodospirillales 204441|Rhodospirillales M Product type - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3 k141_13519_7 1357272.AVEO02000199_gene123 2.27e-86 275.0 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,1RXZP@1236|Gammaproteobacteria,1Z8TJ@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M HlyD family secretion protein - - - - - - - - - - - - Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23 k141_11459_1 1122137.AQXF01000004_gene1816 1.04e-78 253.0 COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,2U1SX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N transport system involved in gliding motility, auxiliary component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_transp_aux k141_10780_1 1033802.SSPSH_001095 1.4e-88 267.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k141_10780_2 697282.Mettu_0764 1.06e-38 137.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1XE51@135618|Methylococcales 135618|Methylococcales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_3116_1 1485544.JQKP01000002_gene1460 2.03e-21 90.5 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,44UZJ@713636|Nitrosomonadales 28216|Betaproteobacteria S ATPase associated with various cellular activities AAA_5 cbbQ2 - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_6526_2 1318628.MARLIPOL_17303 2.17e-12 69.3 COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,46937@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4967 Tfp pilus assembly protein PilV pilV - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k141_19151_2 1150626.PHAMO_280148 2.52e-16 79.7 COG2200@1|root,COG2200@2|Bacteria,1RA10@1224|Proteobacteria,2UTAJ@28211|Alphaproteobacteria,2JX2J@204441|Rhodospirillales 204441|Rhodospirillales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL k141_1716_1 395493.BegalDRAFT_2718 7.88e-05 42.7 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,46173@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin - - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_1716_2 1121374.KB891575_gene1014 3.39e-49 163.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria 1236|Gammaproteobacteria H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_20567_1 367336.OM2255_06590 7.9e-100 319.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC k141_12857_1 1408433.JHXV01000009_gene1319 5.53e-110 326.0 COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2PB5N@246874|Cryomorphaceae 976|Bacteroidetes E Asparaginase aspG GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 ko:K01444,ko:K13051 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 k141_2369_2 331869.BAL199_25454 1.74e-74 251.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,4BPGG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADH5_C,Proton_antipo_M,Proton_antipo_N k141_2369_3 72658.Bostr.11903s0003.1.p 7.61e-55 186.0 COG1007@1|root,KOG4668@2759|Eukaryota 2759|Eukaryota C NADH dehydrogenase (quinone) activity nad5 - 1.6.5.3 ko:K03883 ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012 M00142 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko03029 3.D.1.6 - - LAGLIDADG_1,NADH5_C,Proton_antipo_M,Proton_antipo_N k141_993_1 1122201.AUAZ01000021_gene3217 3.2e-110 333.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,464AT@72275|Alteromonadaceae 1236|Gammaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_10020_1 765910.MARPU_10625 2.32e-80 264.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales 135613|Chromatiales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_6527_1 1121935.AQXX01000142_gene2234 2.19e-32 129.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHWH@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis protein histidine kinase and related - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_8020_1 1288826.MSNKSG1_08828 0.0 917.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,465AN@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL k141_8020_2 1288826.MSNKSG1_08823 1.87e-101 298.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,46612@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313 Inositol_P k141_16292_1 395493.BegalDRAFT_1292 4.25e-31 127.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,4627S@72273|Thiotrichales 72273|Thiotrichales D PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_16292_2 2340.JV46_23670 1.66e-150 440.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N k141_19152_3 998674.ATTE01000001_gene2759 6.28e-11 62.8 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,460J2@72273|Thiotrichales 72273|Thiotrichales F Belongs to the dGTPase family. Type 2 subfamily dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_10782_1 595494.Tola_1243 2.47e-33 131.0 28IZT@1|root,2Z8X3@2|Bacteria,1R4RF@1224|Proteobacteria,1SK6Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10782_2 641491.DND132_1508 1.23e-17 79.7 COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,42PWK@68525|delta/epsilon subdivisions,2WKW1@28221|Deltaproteobacteria,2MA8X@213115|Desulfovibrionales 28221|Deltaproteobacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_3118_1 1278309.KB907101_gene448 9.18e-108 320.0 COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,1RQK2@1236|Gammaproteobacteria,1XHXV@135619|Oceanospirillales 135619|Oceanospirillales S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_19795_1 1408303.JNJJ01000015_gene4489 1.03e-54 191.0 COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus 91061|Bacilli T HD domain cnpD3 - - - - - - - - - - - HD,HD_5 k141_19795_2 626887.J057_20295 2.05e-41 145.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_8646_1 1523503.JPMY01000009_gene621 7.28e-34 128.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_8646_3 305900.GV64_03900 1.89e-127 373.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XHV3@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT k141_2370_1 420324.KI912005_gene8727 8.29e-125 356.0 COG0262@1|root,COG0262@2|Bacteria,1R7YJ@1224|Proteobacteria,2U43B@28211|Alphaproteobacteria,1JUQ8@119045|Methylobacteriaceae 28211|Alphaproteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C k141_20568_1 1278309.KB907108_gene1568 1.08e-61 204.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XHTQ@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 k141_11461_1 1123392.AQWL01000006_gene611 1.18e-133 383.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,1KSYZ@119069|Hydrogenophilales 119069|Hydrogenophilales S CbbQ/NirQ/NorQ C-terminal - - - - - - - - - - - - AAA_5,CbbQ_C k141_12173_1 1278309.KB907099_gene2379 2.37e-263 768.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XHFM@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 k141_11475_1 1116472.MGMO_9c00050 1.93e-19 94.0 COG3284@1|root,COG5001@1|root,COG3284@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9 k141_14236_1 1380380.JIAX01000006_gene1164 1.04e-165 477.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component MA20_30170 - - - - - - - - - - - DctM k141_5165_1 316067.Geob_1314 1.64e-35 135.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42UVA@68525|delta/epsilon subdivisions,2X619@28221|Deltaproteobacteria 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_16312_1 999611.KI421504_gene1692 7.91e-60 188.0 COG0589@1|root,COG0589@2|Bacteria,1PH35@1224|Proteobacteria,2V275@28211|Alphaproteobacteria,28219@191028|Leisingera 28211|Alphaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp k141_16312_2 1569209.BBPH01000001_gene947 2.54e-07 51.6 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2PVS1@265|Paracoccus 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_3796_1 583355.Caka_2077 6.95e-22 93.2 COG0715@1|root,COG0715@2|Bacteria,46U9E@74201|Verrucomicrobia,3K8I0@414999|Opitutae 414999|Opitutae P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_17767_1 323261.Noc_1667 1.83e-133 386.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1WWWT@135613|Chromatiales 135613|Chromatiales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_19812_1 643867.Ftrac_1791 3.16e-52 181.0 COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,47NX6@768503|Cytophagia 976|Bacteroidetes M soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein mltF - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_5896_2 1123399.AQVE01000009_gene3089 6.49e-67 216.0 COG5456@1|root,COG5456@2|Bacteria,1RFTY@1224|Proteobacteria,1S4W0@1236|Gammaproteobacteria,461B6@72273|Thiotrichales 72273|Thiotrichales P FixH - - - - - - - - - - - - FixH k141_5896_3 870187.Thini_0595 6.33e-06 47.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales 72273|Thiotrichales P heavy metal translocating P-type ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_1735_1 574966.KB898646_gene3568 3.67e-72 240.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_8669_1 246200.SPO0648 1.38e-132 383.0 COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2TSZU@28211|Alphaproteobacteria,4NADA@97050|Ruegeria 28211|Alphaproteobacteria S ABC transporter substrate-binding protein PnrA-like MA20_34830 - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp k141_19171_1 351016.RAZWK3B_09386 4.76e-85 261.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2TTI4@28211|Alphaproteobacteria,2P1RZ@2433|Roseobacter 28211|Alphaproteobacteria S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_2390_1 1353537.TP2_13620 4.14e-79 248.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,2XP4P@285107|Thioclava 28211|Alphaproteobacteria E Peptidase family M28 amaB GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_14237_1 367336.OM2255_07580 1.4e-79 248.0 COG2807@1|root,COG2807@2|Bacteria,1QV77@1224|Proteobacteria,2TT90@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_9331_1 1123360.thalar_01038 6.93e-115 345.0 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2TRHI@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,CbiA,GATase_3 k141_14940_1 471854.Dfer_1231 7.6e-108 329.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_16313_1 416269.APL_0804 1.07e-44 164.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1Y7X7@135625|Pasteurellales 135625|Pasteurellales M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Z012_06300 - - - - - - - - - - - Sulfatase k141_21940_1 1002340.AFCF01000034_gene3616 1.41e-92 284.0 COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,2TQZZ@28211|Alphaproteobacteria,34FHY@302485|Phaeobacter 28211|Alphaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - Aminotran_1_2,GntR k141_21940_2 1547437.LL06_04550 1.19e-39 141.0 COG1638@1|root,COG1638@2|Bacteria,1PER4@1224|Proteobacteria,2U0Q4@28211|Alphaproteobacteria,43NYQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_10034_1 1288826.MSNKSG1_17256 2.84e-56 189.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_10034_2 1288826.MSNKSG1_17261 4.33e-178 495.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,464N4@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_10034_3 1288826.MSNKSG1_17266 1.63e-120 344.0 2EI3W@1|root,33BVA@2|Bacteria,1NPW4@1224|Proteobacteria,1SGBC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10034_4 1288826.MSNKSG1_17271 2.93e-138 398.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,4654G@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_13536_1 1288826.MSNKSG1_08948 1.54e-114 339.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,463YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k141_13536_2 1288826.MSNKSG1_08953 4.49e-148 417.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,46649@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG - 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG k141_13536_3 1288826.MSNKSG1_08958 9.15e-301 820.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,46522@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_13536_4 1288826.MSNKSG1_08963 1.42e-50 160.0 COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,468MC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the BolA IbaG family yrbA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - - - - - - - - - - BolA k141_13536_5 1288826.MSNKSG1_08968 3.41e-59 183.0 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NTP binding protein (Contains STAS domain) yrbB - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 k141_13536_6 1288826.MSNKSG1_08973 3.27e-147 415.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1SABB@1236|Gammaproteobacteria,467R8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component ttg2D - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_13536_7 1288826.MSNKSG1_08978 1.36e-94 276.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,4678T@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, periplasmic component mlaD GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_13536_8 1288826.MSNKSG1_08983 3.79e-176 492.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,463ZG@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0767 ABC-type transport system involved in resistance to organic solvents, permease component mlaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k141_12885_1 1268239.PALB_20050 5.82e-55 184.0 COG0697@1|root,COG0697@2|Bacteria,1N469@1224|Proteobacteria,1RQ1G@1236|Gammaproteobacteria,2Q0ZN@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_12885_2 247639.MGP2080_08049 6.03e-21 95.1 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_17030_1 1049564.TevJSym_af00210 6.35e-193 548.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1J4NW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO k141_5897_1 398580.Dshi_2603 9.11e-97 298.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria 28211|Alphaproteobacteria E oligoendopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_19813_1 1249627.D779_2147 1.57e-15 71.2 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,1WYI4@135613|Chromatiales 135613|Chromatiales P sulfur relay protein TusB DsrH - - - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_19813_2 1049564.TevJSym_aw00170 1.23e-69 212.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the DsrF TusC family tusC GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_10798_1 243233.MCA2099 4.73e-67 222.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XDR9@135618|Methylococcales 135618|Methylococcales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_3259_1 472759.Nhal_2700 4.3e-38 138.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 k141_3259_2 1183438.GKIL_2979 2.48e-16 77.4 COG0637@1|root,COG0637@2|Bacteria,1G2T2@1117|Cyanobacteria 1117|Cyanobacteria S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - - - - - - - - - - HAD_2 k141_15804_1 1121940.AUDZ01000013_gene647 2.96e-58 193.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XHQ9@135619|Oceanospirillales 135619|Oceanospirillales M heptosyltransferase waaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_7426_1 260799.BAS3306 1.12e-58 191.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,1ZD7C@1386|Bacillus 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_20677_1 95619.PM1_0209415 8.5e-76 235.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO1391,iSDY_1059.SDY_2348 Cytidylate_kin k141_20677_2 520999.PROVALCAL_00840 1.98e-100 309.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,3Z8AH@586|Providencia 1236|Gammaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_17160_2 1437882.AZRU01000100_gene4290 7.64e-59 184.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1YG4X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 k141_19932_1 1121935.AQXX01000098_gene1656 2.85e-46 159.0 COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria,1XPIQ@135619|Oceanospirillales 135619|Oceanospirillales S COG3103 SH3 domain protein - - - - - - - - - - - - OMP_b-brl,SH3_3,SH3_4 k141_3272_1 1288826.MSNKSG1_07188 3.32e-81 243.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k141_3272_2 1288826.MSNKSG1_07193 1.74e-170 476.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,465EW@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - - - - - - - - - - Transcrip_reg k141_3272_3 1288826.MSNKSG1_07198 0.0 1193.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,46435@72275|Alteromonadaceae 1236|Gammaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon k141_3272_4 1396858.Q666_01580 1.92e-124 357.0 COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1RN9W@1236|Gammaproteobacteria,466D9@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator fabR GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K22105 - - - - ko00000,ko03000 - - - TetR_N k141_3272_6 1288826.MSNKSG1_07213 1.97e-87 258.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,467YV@72275|Alteromonadaceae 1236|Gammaproteobacteria FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit1 - - - - - - - - - - - HIT k141_3272_7 1288826.MSNKSG1_07218 9.61e-245 676.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,464Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_2517_2 1149133.ppKF707_4353 5.58e-15 70.5 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_2517_3 323261.Noc_1573 4.36e-21 89.7 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_8179_1 1286106.MPL1_02768 1.81e-71 225.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,460EG@72273|Thiotrichales 72273|Thiotrichales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_8179_2 1116472.MGMO_77c00030 7.56e-149 448.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XDWG@135618|Methylococcales 135618|Methylococcales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_13724_1 1298593.TOL_1879 5.21e-07 50.4 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1XK2S@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein exbD1 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD k141_13724_2 555778.Hneap_1728 1.79e-40 150.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_6671_1 269799.Gmet_2351 1.16e-78 244.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family gnnB - - - - - - - - - - iAF987.Gmet_2351 DegT_DnrJ_EryC1 k141_18558_1 545276.KB898726_gene938 1.61e-47 156.0 COG2210@1|root,COG2210@2|Bacteria,1RCMJ@1224|Proteobacteria,1S2XA@1236|Gammaproteobacteria,1WW76@135613|Chromatiales 135613|Chromatiales S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_18558_2 1077144.AGFF01000023_gene1504 2.25e-21 90.1 COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - iNJ661.Rv1826 GCV_H k141_9434_1 1122201.AUAZ01000001_gene2249 1.82e-64 222.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,4668W@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional activator of acetoin glycerol metabolism - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_23,HTH_8,Sigma54_activat k141_9434_3 1038860.AXAP01000040_gene2869 1.81e-23 103.0 COG0834@1|root,COG0834@2|Bacteria,1QCAG@1224|Proteobacteria,2TT51@28211|Alphaproteobacteria,3JSPR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_9434_4 1461693.ATO10_10495 1.86e-21 90.5 COG2010@1|root,COG2010@2|Bacteria,1N226@1224|Proteobacteria,2UGQM@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_9434_5 1461693.ATO10_10500 2.05e-295 818.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Dehydrogenase - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 k141_9434_6 392500.Swoo_2939 5.73e-92 273.0 COG0346@1|root,COG0346@2|Bacteria,1R8DA@1224|Proteobacteria,1S68W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - 5.1.3.33 ko:K20431 ko00525,ko01130,map00525,map01130 M00815 R11079 RC01519 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase,Glyoxalase_4 k141_9434_7 1168065.DOK_08899 8.23e-12 74.3 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1JAA2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_9434_8 305900.GV64_07130 1.68e-45 149.0 COG0789@1|root,COG0789@2|Bacteria,1N0AR@1224|Proteobacteria,1S9HZ@1236|Gammaproteobacteria,1XMRD@135619|Oceanospirillales 135619|Oceanospirillales K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 k141_9434_9 305900.GV64_07135 1.11e-174 493.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1XITV@135619|Oceanospirillales 135619|Oceanospirillales O DnaJ C terminal domain cbpA - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C k141_9434_11 1121943.KB899995_gene764 3.57e-130 376.0 COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,1RNF7@1236|Gammaproteobacteria,1XHWA@135619|Oceanospirillales 135619|Oceanospirillales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_9434_12 395493.BegalDRAFT_3246 1.43e-110 335.0 COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,1RQ5G@1236|Gammaproteobacteria,4638Q@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system - - - - - - - - - - - - Peripla_BP_6 k141_10933_1 292415.Tbd_1277 1.36e-08 55.8 COG2199@1|root,COG3706@2|Bacteria,1R7KA@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase ydeH GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - CZB,GGDEF k141_10933_2 519989.ECTPHS_01769 1.6e-84 262.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales 135613|Chromatiales O Trypsin - - - ko:K04691 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_7427_1 95619.PM1_0202125 2.05e-107 319.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RSKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM Epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 k141_10196_1 686340.Metal_1050 2.78e-123 400.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_4662_1 1255043.TVNIR_2976 3.76e-22 89.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1WY7Q@135613|Chromatiales 135613|Chromatiales S PFAM Fe-S metabolism associated - - - ko:K02426 - - - - ko00000 - - - SufE k141_4662_2 765910.MARPU_07270 2.58e-50 161.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1WYM7@135613|Chromatiales 135613|Chromatiales S Belongs to the HesB IscA family - - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_4662_3 1530186.JQEY01000009_gene2867 2.81e-42 142.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S FeS assembly SUF system protein mrp - - - - - - - - - - - FeS_assembly_P k141_4662_4 948106.AWZT01000053_gene1579 2.59e-56 191.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2VMJ9@28216|Betaproteobacteria,1K26K@119060|Burkholderiaceae 28216|Betaproteobacteria O Uncharacterized protein family (UPF0051) sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 k141_13042_1 443152.MDG893_07685 3.61e-136 390.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1SZ2D@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - - - - - - - - - - BPD_transp_2 k141_8180_1 1265313.HRUBRA_00771 4.69e-102 300.0 COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,1RSCI@1236|Gammaproteobacteria,1J81E@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_19933_1 246200.SPO3315 1.31e-68 218.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_14343_2 1122128.AUEE01000013_gene22 3.73e-17 85.9 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,4GXKC@90964|Staphylococcaceae 91061|Bacilli I Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway (By similarity) dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat k141_13725_1 1123228.AUIH01000004_gene1016 2.92e-150 432.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1XHVA@135619|Oceanospirillales 135619|Oceanospirillales C Converts isocitrate to alpha ketoglutarate icdA - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k141_3909_1 1116472.MGMO_103c00140 2.19e-18 85.5 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,1T3H9@1236|Gammaproteobacteria,1XDWD@135618|Methylococcales 135618|Methylococcales H Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_3909_2 2340.JV46_22350 8.1e-29 108.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,1J6IA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Cation efflux family czcD1 - - - - - - - - - - - Cation_efflux k141_17902_1 1123503.KB908060_gene144 1.16e-11 65.9 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2TS81@28211|Alphaproteobacteria,2KF61@204458|Caulobacterales 204458|Caulobacterales S Domain of unknown function (DUF1732) - - - - - - - - - - - - DUF1732,YicC_N k141_17902_2 1123360.thalar_01870 1.11e-08 56.6 COG5388@1|root,COG5388@2|Bacteria,1RCVG@1224|Proteobacteria,2U2IX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PAS domain - - - - - - - - - - - - PAS_5 k141_2519_1 225849.swp_3639 4.49e-65 209.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,2QAIG@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM cobalamin synthesis protein P47K yeiR GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - - - - - - - - - - CobW_C,cobW k141_7428_1 1255043.TVNIR_0852 1.03e-80 258.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales 135613|Chromatiales C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2 k141_16454_2 1217705.F900_00701 6.09e-20 90.5 COG3728@1|root,COG3728@2|Bacteria,1RG2M@1224|Proteobacteria,1S5U8@1236|Gammaproteobacteria,3NNZY@468|Moraxellaceae 1236|Gammaproteobacteria L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k141_16454_3 1273707.L7TP33_9CAUD 4.96e-36 142.0 4QFZG@10239|Viruses,4R03J@35237|dsDNA viruses no RNA stage,4QTRK@28883|Caudovirales,4QNP7@10744|Podoviridae 10744|Podoviridae S Pfam:Terminase_3C - - - - - - - - - - - - - k141_470_1 105559.Nwat_2128 6.9e-32 122.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales 135613|Chromatiales F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k141_1182_1 1278309.KB907099_gene2995 1.12e-54 179.0 COG0583@1|root,COG0583@2|Bacteria,1PEG1@1224|Proteobacteria,1S1A9@1236|Gammaproteobacteria,1XJ0W@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_1182_2 1278309.KB907099_gene2996 2.69e-101 307.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI11@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_17162_1 398578.Daci_5533 2.5e-05 47.4 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,4ADJ3@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM VacJ family lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_20679_1 1117318.PRUB_13601 1.44e-18 83.6 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,2Q19G@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K Belongs to the Rsd AlgQ family rsd GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_13043_1 1122137.AQXF01000006_gene802 1.32e-93 286.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate - - - - - - - - - - - - SDF k141_1848_1 384765.SIAM614_16347 2.6e-94 290.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type dipeptide transport system periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_18560_2 340.xcc-b100_1653 1.82e-37 139.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1X3VD@135614|Xanthomonadales 135614|Xanthomonadales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_3274_1 1046714.AMRX01000003_gene241 2.87e-24 101.0 COG0840@1|root,COG0840@2|Bacteria,1MWU2@1224|Proteobacteria,1RR1Q@1236|Gammaproteobacteria,4661J@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_5346_1 1288826.MSNKSG1_11953 0.0 1061.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria,465B0@72275|Alteromonadaceae 1236|Gammaproteobacteria CK Regulator of nitric oxide reductase transcription yccM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19339 - - - - ko00000,ko03000 - - - FMN_bind,Fer4,Fer4_5 k141_5346_2 1288826.MSNKSG1_11943 6.47e-159 448.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,1RMM9@1236|Gammaproteobacteria,4655A@72275|Alteromonadaceae 1236|Gammaproteobacteria S May be involved in the transport of PQQ or its precursor to the periplasm pqqB GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 k141_19314_1 935848.JAEN01000024_gene2588 9.51e-52 189.0 COG0457@1|root,COG0457@2|Bacteria,1R1ZZ@1224|Proteobacteria,2U4KW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans k141_19314_2 314345.SPV1_04088 2.11e-92 277.0 COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria 1224|Proteobacteria S Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_16,PrmA k141_19314_3 1278309.KB907101_gene436 7.43e-58 181.0 2E5A1@1|root,3302A@2|Bacteria,1NCFQ@1224|Proteobacteria,1SCB3@1236|Gammaproteobacteria,1XKYC@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_22057_1 1288826.MSNKSG1_10633 0.0 1332.0 COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,465TG@72275|Alteromonadaceae 1236|Gammaproteobacteria N ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux k141_22057_2 1288826.MSNKSG1_10638 1.16e-125 361.0 2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,467YC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 k141_22057_3 1288826.MSNKSG1_10643 0.0 952.0 COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,465G6@72275|Alteromonadaceae 1236|Gammaproteobacteria C conserved protein containing a ferredoxin-like domain - - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_7,Fer4_8,LUD_dom k141_22057_4 1288826.MSNKSG1_10648 2.32e-151 426.0 COG1556@1|root,COG1556@2|Bacteria,1RJ6A@1224|Proteobacteria,1S7WZ@1236|Gammaproteobacteria,4694P@72275|Alteromonadaceae 1236|Gammaproteobacteria S LUD domain ykgG - - ko:K00782 - - - - ko00000 - - iECO111_1330.ECO111_0342,iECO26_1355.ECO26_0342 LUD_dom k141_22057_5 1288826.MSNKSG1_10653 6.78e-192 536.0 COG0697@1|root,COG0697@2|Bacteria,1MUQ7@1224|Proteobacteria,1SXXM@1236|Gammaproteobacteria,464DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_22057_6 1288826.MSNKSG1_10658 6.89e-138 389.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1RP3M@1236|Gammaproteobacteria,466Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Lactoylglutathione lyase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k141_10197_1 580332.Slit_2150 9.98e-35 128.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - k141_10197_2 314345.SPV1_14149 1.51e-26 106.0 COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria 1224|Proteobacteria P phosphate transport regulator (Distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_13726_2 519989.ECTPHS_01504 5.62e-21 91.3 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_7450_1 1158150.KB906241_gene667 2.67e-191 539.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales 135613|Chromatiales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_14458_1 396588.Tgr7_1124 2.94e-79 244.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13862_1 1278309.KB907103_gene1029 1.03e-125 377.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XH36@135619|Oceanospirillales 135619|Oceanospirillales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim k141_1319_1 580332.Slit_0396 4.55e-72 239.0 COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,2VIRI@28216|Betaproteobacteria 28216|Betaproteobacteria G Glucodextranase, domain N - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - CBM_20,Glucodextran_N,Glyco_hydro_15 k141_8317_1 1288826.MSNKSG1_11248 3.21e-48 164.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4644H@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K01766,ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5,SufE k141_8317_2 1288826.MSNKSG1_11243 2.55e-304 830.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,4644K@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - ko:K09015 - - - - ko00000 - - iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 UPF0051 k141_8317_3 1288826.MSNKSG1_11238 1.89e-177 495.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,4659A@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - ko:K09013 - - - - ko00000,ko02000 - - iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 ABC_tran k141_18077_1 743720.Psefu_0044 7.15e-43 144.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1YWST@136845|Pseudomonas putida group 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_18077_2 443152.MDG893_18067 9.13e-101 309.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,463ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein containing LysM domain lysM - - - - - - - - - - - LysM k141_9583_1 83406.HDN1F_10370 4.44e-12 71.2 COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1J65T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M silverDB VP1757 - - - - - - - - - - - Porin_4 k141_7558_1 1122164.JHWF01000001_gene2017 1.98e-58 192.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1JCER@118969|Legionellales 118969|Legionellales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_21530_2 56110.Oscil6304_2815 1.47e-13 72.8 COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales 1117|Cyanobacteria O Beta-propeller repeat - - - - - - - - - - - - Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP k141_6775_1 1278309.KB907102_gene112 3.11e-27 110.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 k141_6775_2 1278309.KB907102_gene113 0.0 1029.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1XIWR@135619|Oceanospirillales 135619|Oceanospirillales KLT Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,Pkinase k141_6775_3 1278309.KB907102_gene114 4.27e-188 524.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1XHC1@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k141_6775_4 1278309.KB907102_gene115 2.12e-65 204.0 COG0748@1|root,COG0748@2|Bacteria,1REH2@1224|Proteobacteria,1T0AC@1236|Gammaproteobacteria,1XKUH@135619|Oceanospirillales 135619|Oceanospirillales P Pfam:Pyridox_oxidase - - - ko:K07226 - - - - ko00000 - - - Putative_PNPOx k141_16607_1 713586.KB900536_gene3054 3.15e-25 105.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_16607_2 2340.JV46_20400 1.39e-52 180.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1J5MF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NADH ubiquinone oxidoreductase subunit nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_3406_1 686340.Metal_1391 3.17e-112 345.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales 135618|Methylococcales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_17301_2 391595.RLO149_c042620 7.65e-31 117.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,2P292@2433|Roseobacter 28211|Alphaproteobacteria E ornithine cyclodeaminase, mu-crystallin homolog - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_22203_2 998674.ATTE01000001_gene2020 5.31e-63 197.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,460PP@72273|Thiotrichales 72273|Thiotrichales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 k141_22203_3 1033802.SSPSH_001317 1.91e-41 140.0 COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,1SEQ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CbiX cbiX - 4.99.1.4 ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R02864 RC01012 ko00000,ko00001,ko00002,ko01000 - - - CbiX k141_12508_2 1232683.ADIMK_3758 7.63e-33 125.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,4658U@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3267 Type II secretory pathway, component ExeA gspA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 k141_11715_1 1278309.KB907100_gene2086 2.36e-191 546.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XII4@135619|Oceanospirillales 135619|Oceanospirillales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_22210_7 1288826.MSNKSG1_14957 1.43e-218 602.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,464F5@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_22210_8 1288826.MSNKSG1_14962 1.17e-32 114.0 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SGKJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2909) VL23_10685 - - - - - - - - - - - DUF2909 k141_22210_9 1288826.MSNKSG1_14967 4.47e-172 480.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,4684Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k141_22210_10 1288826.MSNKSG1_14972 1.21e-49 162.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,46868@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - k141_18741_1 198628.Dda3937_00142 1.4e-65 215.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,2JDCS@204037|Dickeya 1236|Gammaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Hexapep,Hexapep_2,NTP_transf_3 k141_9601_1 2340.JV46_28240 1.52e-153 459.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_21547_1 367336.OM2255_03725 3.41e-76 229.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_21547_2 1380367.JIBC01000010_gene3611 3.17e-15 74.3 COG2825@1|root,COG2825@2|Bacteria,1MZ4B@1224|Proteobacteria,2UC2P@28211|Alphaproteobacteria,3ZXSE@60136|Sulfitobacter 28211|Alphaproteobacteria M Outer membrane protein (OmpH-like) - - - - - - - - - - - - OmpH k141_17313_1 1278309.KB907101_gene408 1.25e-184 518.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XH8U@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_17313_2 1278309.KB907101_gene407 9.47e-37 125.0 COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria,1XMA0@135619|Oceanospirillales 135619|Oceanospirillales CO Thioredoxin domain - - - - - - - - - - - - Thioredoxin_3 k141_17313_3 1278309.KB907101_gene406 6.23e-205 570.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1XIUZ@135619|Oceanospirillales 135619|Oceanospirillales S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 k141_17313_4 722419.PH505_ao00220 2.22e-40 137.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,2Q2W2@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc k141_17313_5 1278309.KB907101_gene404 3.45e-44 149.0 COG1180@1|root,COG1180@2|Bacteria,1RA4Z@1224|Proteobacteria,1S34Q@1236|Gammaproteobacteria,1XRSI@135619|Oceanospirillales 135619|Oceanospirillales O 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_14,Radical_SAM k141_11100_1 367336.OM2255_07490 1.09e-311 857.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_6789_1 1278309.KB907100_gene1959 2.75e-43 154.0 COG1807@1|root,COG1807@2|Bacteria,1RE4T@1224|Proteobacteria,1S5IF@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_18100_1 1288826.MSNKSG1_04896 4.78e-129 369.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,465SG@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_18100_2 1288826.MSNKSG1_04891 8.17e-96 280.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,4679G@72275|Alteromonadaceae 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_18100_3 1288826.MSNKSG1_04886 4.25e-83 246.0 COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,467QG@72275|Alteromonadaceae 1236|Gammaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod k141_18100_4 1288826.MSNKSG1_04881 7.02e-91 268.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,4678D@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitroreductase ydjA GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - - - - - - - - - - Nitroreductase k141_16616_1 367336.OM2255_04295 1.47e-118 347.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_8903_1 1417296.U879_04190 6.46e-20 88.2 COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q cytochrome P450 pksS - 1.14.14.1 ko:K00493 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko01000 - - - p450 k141_8903_2 1123360.thalar_02629 1.12e-86 266.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases metB - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP k141_1348_1 1168067.JAGP01000001_gene1570 9.33e-109 326.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,45ZW6@72273|Thiotrichales 72273|Thiotrichales J ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_1348_2 90813.JQMT01000001_gene1579 1.97e-27 104.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,460Q4@72273|Thiotrichales 72273|Thiotrichales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k141_13203_1 998674.ATTE01000001_gene3831 4.3e-78 248.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,45ZVV@72273|Thiotrichales 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_22211_1 1121374.KB891585_gene1969 7.15e-122 353.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exodeoxyribonuclease III exoA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_18742_1 2340.JV46_08950 4.78e-25 107.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1J85K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c k141_18742_2 85643.Tmz1t_1913 0.000597 41.6 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2W22R@28216|Betaproteobacteria,2KZRU@206389|Rhodocyclales 206389|Rhodocyclales K two component transcriptional regulator - - - - - - - - - - - - Response_reg,Trans_reg_C k141_19437_1 566466.NOR53_2419 3.33e-92 289.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J8KD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_11101_2 1045856.EcWSU1_00373 3.1e-19 89.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,3X1IE@547|Enterobacter 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_603_1 1278309.KB907102_gene188 2.33e-155 456.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XH5B@135619|Oceanospirillales 135619|Oceanospirillales S permease - - - - - - - - - - - - DctM k141_603_2 1278309.KB907102_gene189 2.37e-89 288.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1XKF3@135619|Oceanospirillales 135619|Oceanospirillales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - SH3_3,Sel1 k141_4816_1 247633.GP2143_00317 3.56e-41 143.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1J528@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Displays ATPase and GTPase activities rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_4816_2 1278309.KB907099_gene2382 6.13e-47 151.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XKZ0@135619|Oceanospirillales 135619|Oceanospirillales G Phosphocarrier protein HPr ptsO - - ko:K08485,ko:K11189 ko02060,map02060 - - - ko00000,ko00001,ko02000 4.A.2.1 - - PTS-HPr k141_4816_3 1278309.KB907099_gene2381 6.52e-279 768.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XI0Q@135619|Oceanospirillales 135619|Oceanospirillales P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_4816_4 1278309.KB907099_gene2380 3.09e-74 226.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1XK14@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0307 family - - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_17314_1 644107.SL1157_3186 2.85e-42 147.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,4N9U7@97050|Ruegeria 28211|Alphaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_17314_2 52598.EE36_05888 3.47e-27 106.0 COG0340@1|root,COG0340@2|Bacteria,1N1WU@1224|Proteobacteria,2TQK4@28211|Alphaproteobacteria,3ZVXQ@60136|Sulfitobacter 28211|Alphaproteobacteria H Biotin/lipoate A/B protein ligase family - - - - - - - - - - - - BPL_LplA_LipB_2,DUF4444 k141_12518_2 713587.THITH_03215 1.17e-36 130.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity - - - - - - - - - - - - CBS k141_20774_1 1278309.KB907105_gene1444 7.13e-25 111.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,1XIPK@135619|Oceanospirillales 135619|Oceanospirillales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_18101_1 1278309.KB907100_gene2050 1.09e-92 282.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1XH2Y@135619|Oceanospirillales 135619|Oceanospirillales F Dihydroorotase multifunctional complex type pyrC-2 - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_18101_2 1278309.KB907100_gene2051 1.94e-32 122.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1XI42@135619|Oceanospirillales 135619|Oceanospirillales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_2682_1 391626.OAN307_c30220 4.3e-89 269.0 COG0697@1|root,COG0697@2|Bacteria,1R3W3@1224|Proteobacteria,2TS0I@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_8333_2 425104.Ssed_1962 9.77e-52 167.0 2CG3F@1|root,32S32@2|Bacteria,1N1SR@1224|Proteobacteria,1SBQB@1236|Gammaproteobacteria,2QC0V@267890|Shewanellaceae 1236|Gammaproteobacteria S Ribonucleotide reductase subunit alpha - - - - - - - - - - - - - k141_8333_4 1278309.KB907100_gene2241 4.75e-179 504.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,1XJAZ@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_8333_5 1278309.KB907100_gene2240 2.07e-187 528.0 COG3203@1|root,COG3203@2|Bacteria,1PCGZ@1224|Proteobacteria,1SXHW@1236|Gammaproteobacteria,1XPGW@135619|Oceanospirillales 135619|Oceanospirillales M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k141_8333_6 1278309.KB907100_gene2239 4.7e-210 587.0 COG3490@1|root,COG3490@2|Bacteria,1NNS5@1224|Proteobacteria,1S3YB@1236|Gammaproteobacteria,1XHF0@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09947 - - - - ko00000 - - - DUF1513 k141_8333_7 1278309.KB907100_gene2238 2.1e-185 524.0 COG3489@1|root,COG3489@2|Bacteria,1MWBW@1224|Proteobacteria,1S2FI@1236|Gammaproteobacteria,1XJGA@135619|Oceanospirillales 135619|Oceanospirillales S Imelysin - - - ko:K07338 - - - - ko00000 - - - Peptidase_M75 k141_8333_8 1278309.KB907100_gene2237 2.31e-110 330.0 COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,1XI71@135619|Oceanospirillales 135619|Oceanospirillales C Thiol oxidoreductase - - - - - - - - - - - - DHOR k141_11102_1 187272.Mlg_2789 7.61e-31 116.0 COG1802@1|root,COG1802@2|Bacteria,1PVIG@1224|Proteobacteria,1SBXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator mdcY - - - - - - - - - - - FCD,GntR k141_11102_2 1231190.NA8A_14801 1.43e-22 95.5 COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,2TV91@28211|Alphaproteobacteria,43NPF@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component MA20_30160 - - - - - - - - - - - DctP k141_8905_1 1248232.BANQ01000086_gene2750 3.36e-48 159.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XT4Z@135623|Vibrionales 135623|Vibrionales K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_8905_2 1440052.EAKF1_ch3427c 1.74e-08 55.1 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,3XMYY@561|Escherichia 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_10373_1 460265.Mnod_4678 5.61e-101 315.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,1JS86@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM glucose-methanol-choline oxidoreductase MA20_17575 - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k141_10373_2 1026882.MAMP_00816 1.23e-22 94.4 2EHQA@1|root,33BG2@2|Bacteria,1NNCK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - Gluconate_2-dh3 k141_19438_1 1234364.AMSF01000025_gene3645 8.74e-72 231.0 COG0457@1|root,COG0457@2|Bacteria,1MVH9@1224|Proteobacteria,1RQ3R@1236|Gammaproteobacteria,1X3F2@135614|Xanthomonadales 135614|Xanthomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 k141_5688_2 393595.ABO_1462 6.17e-67 211.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1XJI9@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k141_21043_1 522306.CAP2UW1_3335 1.26e-30 108.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,1KQY2@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_1468_1 713586.KB900536_gene1624 2.52e-56 181.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity yafP - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 k141_1468_2 765913.ThidrDRAFT_3104 1.84e-56 190.0 COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,1RP1Y@1236|Gammaproteobacteria,1WWDI@135613|Chromatiales 135613|Chromatiales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_9827_1 1122603.ATVI01000006_gene31 2.3e-08 59.3 COG4726@1|root,COG4726@2|Bacteria,1N7KP@1224|Proteobacteria,1SCM5@1236|Gammaproteobacteria,1X796@135614|Xanthomonadales 135614|Xanthomonadales NU Type IV pilus assembly protein PilX C-term - - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX,PilX_N k141_4248_1 1122201.AUAZ01000023_gene3000 9.42e-132 378.0 COG4778@1|root,COG4778@2|Bacteria,1MUPB@1224|Proteobacteria,1RS1I@1236|Gammaproteobacteria,46ASM@72275|Alteromonadaceae 1236|Gammaproteobacteria P TIGRFAM phosphonate C-P lyase system protein PhnL phnL GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1990234 2.7.8.37 ko:K05780 ko00440,map00440 - R10185 RC00005,RC00063 ko00000,ko00001,ko01000 - - - ABC_tran k141_4248_2 1122201.AUAZ01000023_gene3001 4.74e-206 577.0 COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,1RMR7@1236|Gammaproteobacteria,46A1B@72275|Alteromonadaceae 1236|Gammaproteobacteria P Amidohydrolase family phnM GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0044237,GO:0046434,GO:0071704,GO:1901575 3.6.1.63 ko:K06162 ko00440,map00440 - R10186 RC00002 ko00000,ko00001,ko01000 - - - Amidohydro_1,Amidohydro_3 k141_4248_3 1286170.RORB6_17005 3.43e-46 157.0 COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,1S3VA@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) phnN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019634,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.23 ko:K05774 ko00030,map00030 - R06836 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b4094,iB21_1397.B21_03926,iBWG_1329.BWG_3809,iECBD_1354.ECBD_3936,iECB_1328.ECB_03966,iECDH10B_1368.ECDH10B_4285,iECDH1ME8569_1439.ECDH1ME8569_3953,iECD_1391.ECD_03966,iEKO11_1354.EKO11_4224,iEcDH1_1363.EcDH1_3897,iEcolC_1368.EcolC_3932,iJO1366.b4094,iSSON_1240.SSON_4270,iUMNK88_1353.UMNK88_4960,iY75_1357.Y75_RS21315 AAA_18,Guanylate_kin k141_4248_4 1122201.AUAZ01000023_gene3003 1.49e-119 348.0 COG1235@1|root,COG1235@2|Bacteria,1P9QI@1224|Proteobacteria,1RQPE@1236|Gammaproteobacteria,46726@72275|Alteromonadaceae 1236|Gammaproteobacteria S PFAM beta-lactamase domain protein phnP GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016788,GO:0019634,GO:0019637,GO:0019700,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046434,GO:0046872,GO:0046914,GO:0071704,GO:1901575 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 k141_9139_1 1158150.KB906241_gene1105 4.15e-57 191.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales 135613|Chromatiales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_7048_1 1278309.KB907099_gene2837 5.95e-131 380.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XHDY@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N k141_14737_1 1159870.KB907784_gene3124 1.62e-10 61.2 COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,3T1DZ@506|Alcaligenaceae 28216|Betaproteobacteria G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase k141_14737_2 1278309.KB907110_gene3161 4.67e-120 343.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1XHK4@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase k141_14737_3 1278309.KB907110_gene3162 3.35e-132 384.0 COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,1XITR@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09781 - - - - ko00000 - - - DUF808 k141_20323_1 987059.RBXJA2T_17387 1.65e-59 194.0 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2VKIZ@28216|Betaproteobacteria,1KK4H@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_20323_2 717773.Thicy_1032 4.71e-14 67.8 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,1SDWW@1236|Gammaproteobacteria,462MF@72273|Thiotrichales 72273|Thiotrichales K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_21045_1 1121374.KB891586_gene2650 3.79e-78 241.0 2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S3VD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3581) SO4011 - - - - - - - - - - - DUF3581 k141_20324_2 375286.mma_2151 9.27e-17 80.1 COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,4729R@75682|Oxalobacteraceae 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_17478_1 1288826.MSNKSG1_04246 2.97e-182 527.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Phosphoketolase xfp GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k141_17478_2 1288826.MSNKSG1_04256 9.59e-120 342.0 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria 1236|Gammaproteobacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - NMD3 k141_17478_3 1288826.MSNKSG1_04261 0.0 1013.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465W0@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein VPA0491 - - ko:K03406,ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,HBM,MCPsignal k141_17478_4 1288826.MSNKSG1_04266 5.81e-195 543.0 COG0224@1|root,COG0224@2|Bacteria,1N4GR@1224|Proteobacteria,1RYRI@1236|Gammaproteobacteria,469X2@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0224 F0F1-type ATP synthase, gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_17478_5 1288826.MSNKSG1_04271 0.0 931.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria,469W4@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_17478_6 1288826.MSNKSG1_04276 4.81e-126 365.0 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,1S5EV@1236|Gammaproteobacteria,46AQI@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF1 - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP k141_17478_7 1288826.MSNKSG1_04281 1.47e-53 168.0 COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria,46B92@72275|Alteromonadaceae 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_17478_8 1288826.MSNKSG1_04286 7.87e-153 431.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1S0SN@1236|Gammaproteobacteria,469DQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB1 - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_17478_10 1288826.MSNKSG1_04296 5.18e-64 196.0 2CBNW@1|root,32RTR@2|Bacteria,1N7RB@1224|Proteobacteria,1SAT0@1236|Gammaproteobacteria,46BD5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 k141_17478_11 1288826.MSNKSG1_04301 1.7e-85 253.0 COG0355@1|root,COG0355@2|Bacteria,1RKXG@1224|Proteobacteria,1SAMJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane - - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N k141_17478_12 1288826.MSNKSG1_04306 2.16e-303 830.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria,46A6Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD1 - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_17478_13 225937.HP15_1326 3.17e-164 480.0 2DM3X@1|root,31MK7@2|Bacteria,1RFI0@1224|Proteobacteria,1S7WP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21046_1 1288826.MSNKSG1_02238 1.6e-52 166.0 COG3978@1|root,COG3978@2|Bacteria,1PIDJ@1224|Proteobacteria,1SXZV@1236|Gammaproteobacteria,46996@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit ilvM - 2.2.1.6 ko:K11258 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5 k141_21046_2 1288826.MSNKSG1_02243 1.29e-292 806.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,464TT@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_18903_1 207954.MED92_00685 5.38e-18 77.4 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1XM21@135619|Oceanospirillales 135619|Oceanospirillales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_18903_2 1249627.D779_0874 8.29e-31 113.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1WY0F@135613|Chromatiales 135613|Chromatiales P PFAM Rhodanese-like - - - - - - - - - - - - Rhodanese k141_20326_1 1026882.MAMP_00769 1.26e-69 236.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales 72273|Thiotrichales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_8439_1 522373.Smlt2344 6.6e-88 281.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1X4F7@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein ftsk ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - Cupin_4,FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_18208_1 414684.RC1_1770 6.52e-63 202.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,2JPF8@204441|Rhodospirillales 204441|Rhodospirillales O prohibitin homologues - - - - - - - - - - - - Band_7,Band_7_C k141_2861_1 1122201.AUAZ01000033_gene3253 1.24e-11 62.0 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,466UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions rraA - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like k141_2861_2 1042375.AFPL01000036_gene3081 6.86e-72 219.0 COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,1S4EZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q phenylacetic acid degradation protein paaI GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_1225,iEC55989_1330.EC55989_1532,iECDH10B_1368.ECDH10B_1521,iECDH1ME8569_1439.EcDH1_2249,iECIAI1_1343.ECIAI1_1396,iECO103_1326.ECO103_1533,iECO111_1330.ECO111_1790,iECO26_1355.ECO26_2000,iECSE_1348.ECSE_1481,iEKO11_1354.EKO11_2417,iETEC_1333.ETEC_1471,iEcDH1_1363.EcDH1_2249,iEcE24377_1341.EcE24377A_1581,iEcHS_1320.EcHS_A1483,iEcolC_1368.EcolC_2259,iUMNK88_1353.UMNK88_1803,iY75_1357.Y75_RS07340 4HBT k141_2861_3 1042375.AFPL01000036_gene3082 1.38e-85 268.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RPVB@1236|Gammaproteobacteria,469UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain paaH GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1532,iJN746.PP_3282 3HCDH,3HCDH_N k141_16815_1 4565.Traes_4BS_A8F01CCC5.1 1.09e-16 79.3 COG0002@1|root,KOG4354@2759|Eukaryota,37R6A@33090|Viridiplantae,3G7HC@35493|Streptophyta,3KT4T@4447|Liliopsida,3I998@38820|Poales 35493|Streptophyta E N-acetyl-gamma-glutamyl-phosphate reductase - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0010035,GO:0010038,GO:0016020,GO:0031974,GO:0031981,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0070013 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_16815_2 314271.RB2654_02519 1e-38 137.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_12632_1 397945.Aave_4401 7.73e-77 244.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,4ACM7@80864|Comamonadaceae 28216|Betaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC - - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_12632_2 396588.Tgr7_1227 6.59e-90 283.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1WX4A@135613|Chromatiales 135613|Chromatiales N TIGRFAM Flagellar hook-associated protein 3 - - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_11943_1 1056820.KB900643_gene803 1.6e-53 187.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,2PMJ8@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria U TolB amino-terminal domain tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_11943_2 1380387.JADM01000019_gene3290 1.9e-12 72.4 COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,1T2GY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tolA - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_2,TonB_C k141_3571_1 1288826.MSNKSG1_17551 0.0 903.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46410@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_3571_2 1288826.MSNKSG1_17556 3.55e-115 332.0 COG5010@1|root,COG5010@2|Bacteria,1QXG4@1224|Proteobacteria,1T3B8@1236|Gammaproteobacteria,46C82@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19 k141_3571_3 1288826.MSNKSG1_17561 5.67e-40 140.0 2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 k141_775_1 1249627.D779_1804 1.7e-189 534.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k141_4939_1 155515.JP36_05145 1.53e-11 68.2 COG3676@1|root,COG3676@2|Bacteria,1R7ZF@1224|Proteobacteria,1S6YQ@1236|Gammaproteobacteria,1Y7XM@135625|Pasteurellales 135625|Pasteurellales L ISXO2-like transposase domain - - - ko:K07488 - - - - ko00000 - - - DDE_Tnp_IS1595 k141_7788_1 1530186.JQEY01000013_gene71 3.32e-55 182.0 COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_15472_1 83406.HDN1F_13910 4.46e-13 70.5 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1JA1H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T HDOD domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_15472_2 105559.Nwat_2131 2.88e-64 207.0 COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,1RQES@1236|Gammaproteobacteria,1WXQ1@135613|Chromatiales 135613|Chromatiales S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans k141_20347_1 391615.ABSJ01000037_gene961 1.45e-70 227.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1J578@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolC GO:0005575,GO:0005623,GO:0005886,GO:0008104,GO:0008150,GO:0016020,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_9843_1 522772.Dacet_0923 0.000303 45.4 COG3221@1|root,COG3221@2|Bacteria,2GFC9@200930|Deferribacteres 200930|Deferribacteres P TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_12651_1 156889.Mmc1_0425 1.34e-08 61.2 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 2|Bacteria T Histidine kinase barA - - - - - - - - - - - CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,SBP_bac_3 k141_12651_2 1317124.DW2_12150 1.8e-33 120.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,2UCYS@28211|Alphaproteobacteria,2XNU0@285107|Thioclava 28211|Alphaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_8466_1 414684.RC1_1438 7.56e-148 449.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2JPN7@204441|Rhodospirillales 204441|Rhodospirillales L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_2176_1 246200.SPO1984 4.61e-49 168.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,4NBIQ@97050|Ruegeria 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_2176_2 216596.RL4682 2.1e-20 89.7 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,4B9BB@82115|Rhizobiaceae 28211|Alphaproteobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_11290_1 1279019.ARQK01000050_gene1319 5.67e-42 152.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1SKRF@1236|Gammaproteobacteria,1WZYV@135613|Chromatiales 135613|Chromatiales T HDOD domain - - - - - - - - - - - - EAL,HDOD k141_18224_1 1234364.AMSF01000027_gene3463 8.44e-77 246.0 COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,1X6KU@135614|Xanthomonadales 135614|Xanthomonadales U Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - - - - - - - - - - POTRA_2,ShlB k141_7065_1 1123234.AUKI01000016_gene3052 2.56e-60 199.0 COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia 976|Bacteroidetes E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related dapE - - - - - - - - - - - M20_dimer,Peptidase_M20 k141_800_1 84531.JMTZ01000117_gene4259 1.04e-97 289.0 COG0546@1|root,COG0546@2|Bacteria,1QTZ0@1224|Proteobacteria,1RZWV@1236|Gammaproteobacteria,1X5KH@135614|Xanthomonadales 135614|Xanthomonadales S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 k141_14051_1 643867.Ftrac_1987 4.61e-90 290.0 COG0842@1|root,COG1131@1|root,COG4103@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG4103@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran,TerB k141_19611_1 765913.ThidrDRAFT_2502 2.42e-99 299.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1WXW8@135613|Chromatiales 135613|Chromatiales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_18927_1 396588.Tgr7_1915 3.1e-103 312.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_18927_2 519989.ECTPHS_10386 1.61e-101 311.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales 135613|Chromatiales CI TIGRFAM Oxaloacetate decarboxylase, alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_21066_1 1278309.KB907099_gene2531 6.59e-277 781.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_4273_1 765914.ThisiDRAFT_2385 3.07e-92 287.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M k141_4273_2 1298593.TOL_0801 4.85e-16 80.9 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XHZM@135619|Oceanospirillales 135619|Oceanospirillales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_1485_1 1278309.KB907103_gene1043 2.34e-61 189.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XK9E@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional - - - ko:K22042 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 k141_1485_2 1278309.KB907103_gene1044 3.35e-292 819.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XISF@135619|Oceanospirillales 135619|Oceanospirillales M Sterol-sensing domain of SREBP cleavage-activation - - - ko:K07003 - - - - ko00000 - - - MMPL k141_18225_1 440512.C211_16365 4.21e-06 48.9 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_6366_1 317025.Tcr_0049 9.46e-173 492.0 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales 72273|Thiotrichales O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_3596_1 1168067.JAGP01000001_gene1305 2.41e-86 265.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria,4625T@72273|Thiotrichales 72273|Thiotrichales N MotA/TolQ/ExbB proton channel family - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_9844_1 1229909.NSED_09755 1.42e-58 184.0 COG0529@1|root,arCOG01040@2157|Archaea 2157|Archaea F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25 ko:K00860,ko:K07028 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - AAA_33,APS_kinase k141_9844_2 1229909.NSED_09760 1.59e-54 177.0 COG0483@1|root,arCOG01349@2157|Archaea,41T8P@651137|Thaumarchaeota 651137|Thaumarchaeota G Inositol monophosphatase - - 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 - - - Inositol_P k141_11291_1 1449351.RISW2_00780 6.57e-96 306.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,4KM7U@93682|Roseivivax 28211|Alphaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism glnD GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 k141_2177_1 751994.AGIG01000028_gene2023 4.3e-47 167.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1J4J8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family ybaL - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N k141_18928_1 400668.Mmwyl1_1980 7.36e-41 144.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XK05@135619|Oceanospirillales 135619|Oceanospirillales P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_19612_1 313606.M23134_06014 9.48e-44 162.0 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP k141_2882_1 1278309.KB907100_gene1848 2.78e-134 417.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_9 k141_10561_1 1120919.AUBI01000002_gene1241 1.13e-26 107.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,2JPI2@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_17699_3 1288826.MSNKSG1_10598 7.52e-141 411.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,464PW@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iJN746.PP_2845 Amidohydro_1,Urease_alpha k141_9968_2 1122599.AUGR01000010_gene1018 2.47e-12 63.5 2EPBF@1|root,33GY7@2|Bacteria,1NHWE@1224|Proteobacteria,1SHUW@1236|Gammaproteobacteria,1XMPW@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9968_3 1278309.KB907099_gene2699 2.39e-125 363.0 COG0345@1|root,COG0345@2|Bacteria,1RGSU@1224|Proteobacteria,1S8AY@1236|Gammaproteobacteria,1XPYG@135619|Oceanospirillales 135619|Oceanospirillales E Pyrroline-5-carboxylate reductase - - - - - - - - - - - - - k141_9968_4 1278309.KB907099_gene2700 7.55e-302 823.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RQ0P@1236|Gammaproteobacteria,1XI6D@135619|Oceanospirillales 135619|Oceanospirillales P Rieske 2Fe-2S - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A k141_9968_5 1278309.KB907099_gene2701 1.21e-192 540.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,1XHA6@135619|Oceanospirillales 135619|Oceanospirillales C Ferredoxin - - - ko:K21832 - - - - ko00000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_3061_1 1434325.AZQN01000002_gene810 6.4e-32 120.0 COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,47MBX@768503|Cytophagia 976|Bacteroidetes O Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3,2OG-FeII_Oxy_4 k141_12805_1 1116472.MGMO_103c00140 1.48e-83 261.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,1T3H9@1236|Gammaproteobacteria,1XDWD@135618|Methylococcales 135618|Methylococcales H Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_12805_2 765912.Thimo_2102 1.08e-37 136.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1WW0K@135613|Chromatiales 135613|Chromatiales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_950_1 1232683.ADIMK_2928 6.14e-61 199.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,464E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_7226_2 157783.LK03_10105 3.01e-12 68.2 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 k141_4477_1 391615.ABSJ01000022_gene301 1.03e-66 214.0 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1J6PK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_4477_2 261292.Nit79A3_3206 7.65e-32 119.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,372US@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF692) - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_19125_2 1123237.Salmuc_00914 5.59e-15 73.6 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_7981_1 1267005.KB911256_gene1838 7.12e-59 202.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,3N6EE@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria CP NADH-quinone oxidoreductase chain L nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADH5_C,Proton_antipo_M,Proton_antipo_N k141_17719_1 1278309.KB907111_gene3388 8.62e-120 345.0 COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,1S3TT@1236|Gammaproteobacteria,1XJAV@135619|Oceanospirillales 135619|Oceanospirillales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_17719_2 322710.Avin_16390 1.99e-309 867.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate - - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_17719_3 1042375.AFPL01000022_gene2652 3.16e-226 630.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed thlA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_17719_4 1278309.KB907111_gene3396 4.94e-305 842.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1XHX6@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_17719_5 1278309.KB907099_gene2574 2.1e-143 441.0 COG4564@1|root,COG5000@1|root,COG4564@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1T35N@1236|Gammaproteobacteria,1XRT7@135619|Oceanospirillales 135619|Oceanospirillales T Cache_2 - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,Response_reg,dCache_2 k141_1696_1 246194.CHY_1732 2e-28 113.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42I2K@68295|Thermoanaerobacterales 186801|Clostridia C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_265_1 1123501.KB902291_gene1483 2.92e-41 147.0 COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_12828_1 870187.Thini_3384 4.01e-118 355.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,4608M@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k141_9299_1 1122201.AUAZ01000008_gene484 8.69e-133 389.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b k141_20540_1 768671.ThimaDRAFT_2212 1.1e-34 132.0 COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,1SKFJ@1236|Gammaproteobacteria,1X099@135613|Chromatiales 135613|Chromatiales L COG0841 Cation multidrug efflux pump - - - - - - - - - - - - DDE_Tnp_1 k141_14207_1 1123368.AUIS01000023_gene933 1.76e-40 158.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 k141_14207_2 1260251.SPISAL_04010 2.69e-21 89.4 COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_3084_1 367336.OM2255_07370 1.75e-140 410.0 COG2248@1|root,COG2248@2|Bacteria,1MVZY@1224|Proteobacteria,2TTII@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative, 10TM heavy-metal exporter - - - - - - - - - - - - ArsP_2 k141_7253_2 1226994.AMZB01000138_gene5579 1.1e-07 52.0 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1YG7Q@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G Phosphoglycerate mutase family cobC - 3.1.3.73,5.4.2.12 ko:K02226,ko:K15634 ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00122 R01518,R04594,R11173 RC00017,RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 k141_9988_1 768671.ThimaDRAFT_1370 4.23e-104 313.0 COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_19782_2 870187.Thini_4133 2.53e-79 253.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,461SS@72273|Thiotrichales 72273|Thiotrichales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_266_1 998088.B565_0493 3.01e-49 171.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1Y3TY@135624|Aeromonadales 135624|Aeromonadales L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C k141_3763_1 1288826.MSNKSG1_16271 2.29e-139 423.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_7254_1 1232683.ADIMK_0255 5.7e-42 149.0 2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria,4650V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - DUF1329 k141_7254_2 1121374.KB891576_gene388 6.52e-27 109.0 28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,1T4JE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21892_1 1232683.ADIMK_3684 2.61e-71 229.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB k141_21892_2 1278309.KB907100_gene2231 2.6e-113 347.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales 135619|Oceanospirillales P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_9989_2 204773.HEAR3342 1.32e-25 106.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2W94M@28216|Betaproteobacteria,47825@75682|Oxalobacteraceae 28216|Betaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain - - 1.8.5.6 ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k141_15612_1 1479237.JMLY01000001_gene3656 0.0 968.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,464YG@72275|Alteromonadaceae 1236|Gammaproteobacteria EI Allophanate hydrolase subunit 1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_9301_1 1304885.AUEY01000030_gene2419 9.78e-78 248.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MHMW@213118|Desulfobacterales 28221|Deltaproteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_267_1 886293.Sinac_2458 4.04e-05 45.8 COG0399@1|root,COG0399@2|Bacteria,2IXZR@203682|Planctomycetes 203682|Planctomycetes E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k141_267_2 105559.Nwat_1363 4.2e-48 165.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales 135613|Chromatiales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB k141_7255_1 1122137.AQXF01000007_gene3560 3.34e-58 202.0 COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_21893_1 301.JNHE01000004_gene1590 1.63e-97 297.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_5133_1 1288826.MSNKSG1_14362 8.21e-147 422.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,465J8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the binding-protein-dependent transport system permease family fmdF - - ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_5133_2 1288826.MSNKSG1_14357 1.81e-167 469.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,465GB@72275|Alteromonadaceae 1236|Gammaproteobacteria S ABC-type transport system, ATPase component livG - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_5133_3 1288826.MSNKSG1_14352 9.31e-152 427.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,464Y5@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k141_18402_1 1158762.KB898043_gene1044 5.85e-12 68.2 COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_19783_1 136993.KB900626_gene2685 4.37e-65 214.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,36XC2@31993|Methylocystaceae 28211|Alphaproteobacteria S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase,Methyltransf_33 k141_10761_1 1122137.AQXF01000006_gene847 2.26e-29 114.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family MA20_09415 - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_973_1 1278309.KB907099_gene2383 1.59e-134 386.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XIUA@135619|Oceanospirillales 135619|Oceanospirillales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_973_2 1278309.KB907099_gene2384 2.84e-77 233.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1XKFB@135619|Oceanospirillales 135619|Oceanospirillales G PTS fructose transporter subunit IIA ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_973_3 1278309.KB907099_gene2385 4.45e-59 182.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XKFR@135619|Oceanospirillales 135619|Oceanospirillales J seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing - - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_973_4 1278309.KB907099_gene2386 2.12e-42 150.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XH8A@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_16994_1 1288826.MSNKSG1_07823 0.0 938.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,464J5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF k141_16994_2 1288826.MSNKSG1_07828 4.15e-184 512.0 COG2207@1|root,COG2207@2|Bacteria,1REAN@1224|Proteobacteria,1SYZS@1236|Gammaproteobacteria,46CNB@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 k141_16994_3 1288826.MSNKSG1_07833 1.44e-137 390.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,466N6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin k141_16994_4 1288826.MSNKSG1_07838 6.81e-250 686.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,4650E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG k141_16994_5 1288826.MSNKSG1_07843 1.72e-162 458.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,467J1@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Aminotran_4 k141_16994_6 1288826.MSNKSG1_07848 6.5e-287 785.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,463YA@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365 Ketoacyl-synt_C,ketoacyl-synt k141_16994_8 1288826.MSNKSG1_07858 1.48e-81 246.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710 adh_short_C2 k141_20542_1 377629.TERTU_0418 6.83e-73 226.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,2PNBR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E CobB/CobQ-like glutamine amidotransferase domain hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_21235_1 1288826.MSNKSG1_17176 2.27e-152 430.0 COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,1S2CW@1236|Gammaproteobacteria,466G8@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) ybfF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - ko:K01175 - - - - ko00000,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_21235_3 1288826.MSNKSG1_17166 1.08e-135 390.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator oruR - - - - - - - - - - - Arabinose_bd,HTH_18 k141_15613_1 553385.JEMF01000089_gene2986 1.45e-13 72.4 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1XI9A@135619|Oceanospirillales 135619|Oceanospirillales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_15613_2 367336.OM2255_12225 1.07e-07 52.4 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_14913_1 1247024.JRLH01000006_gene2667 7.45e-12 65.5 2AHMX@1|root,317ZV@2|Bacteria,1PZIR@1224|Proteobacteria,1SU9H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14208_1 1424334.W822_21000 2.91e-27 110.0 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,2VP9I@28216|Betaproteobacteria,3T2BI@506|Alcaligenaceae 28216|Betaproteobacteria S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_17721_2 1197906.CAJQ02000009_gene3646 2.58e-11 64.7 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,3JV0U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K LysR family oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_13508_1 1366046.HIMB11_00257 1.05e-19 88.2 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,3ZHGQ@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Glutathione S-transferase yibF - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_13508_2 1177181.T9A_00266 3.23e-88 270.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria,1XM9N@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF2189 k141_13508_5 396588.Tgr7_1593 1.53e-28 110.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1WWUF@135613|Chromatiales 135613|Chromatiales S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin k141_4490_1 1278309.KB907107_gene1721 4.11e-42 149.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XHGZ@135619|Oceanospirillales 135619|Oceanospirillales NU Involved in type III protein export during flagellum assembly fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_4490_2 1278309.KB907107_gene1722 7.79e-76 238.0 COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,1RR8H@1236|Gammaproteobacteria,1XM32@135619|Oceanospirillales 135619|Oceanospirillales NU Flagellar assembly protein FliH fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH k141_4490_3 1278309.KB907107_gene1723 1.27e-185 521.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XHXX@135619|Oceanospirillales 135619|Oceanospirillales N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_1698_1 28258.KP05_01680 2.35e-08 53.9 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XK48@135619|Oceanospirillales 135619|Oceanospirillales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_1698_2 349521.HCH_06554 2.97e-66 204.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1XK11@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin - - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_1698_3 1177154.Y5S_02425 2.53e-18 78.2 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1XM21@135619|Oceanospirillales 135619|Oceanospirillales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_12129_1 1288826.MSNKSG1_07778 4.19e-170 482.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,46DAS@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain macB - - ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - FtsX,MacB_PCD k141_12129_2 1288826.MSNKSG1_07773 3.38e-93 271.0 COG0824@1|root,COG0824@2|Bacteria,1MZFI@1224|Proteobacteria,1S8XF@1236|Gammaproteobacteria,467SW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_12129_3 1288826.MSNKSG1_07768 4.09e-186 519.0 28NXH@1|root,2ZBV3@2|Bacteria,1RDDP@1224|Proteobacteria,1S4JV@1236|Gammaproteobacteria,46B1T@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12129_4 1288826.MSNKSG1_07763 2.5e-172 481.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,466F4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - iE2348C_1286.E2348C_0457 Metallophos,Metallophos_2 k141_12129_5 1288826.MSNKSG1_07758 4.08e-120 342.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,466DM@72275|Alteromonadaceae 1236|Gammaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase k141_12129_6 1288826.MSNKSG1_07753 0.0 1156.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,464TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_12129_7 1288826.MSNKSG1_07748 0.0 906.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,464RP@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECUMN_1333.ECUMN_0566,iJN746.PP_2905 DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_12129_8 1288826.MSNKSG1_07743 0.0 1355.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,464G0@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009436,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iJN746.PP_0356,iWFL_1372.ECW_m3242 Malate_synthase k141_5134_1 1231392.OCGS_1977 7.75e-91 281.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k141_10762_1 1123367.C666_13860 5.22e-35 125.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales 206389|Rhodocyclales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_10762_2 1183438.GKIL_0293 2.88e-07 52.4 COG2802@1|root,COG2802@2|Bacteria,1G0PB@1117|Cyanobacteria 1117|Cyanobacteria S to the N-terminal domain of Lon protease' lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg k141_5683_2 1163408.UU9_00255 2.63e-26 110.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1X4ST@135614|Xanthomonadales 135614|Xanthomonadales S Large extracellular alpha-helical protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1 k141_9134_1 1278309.KB907107_gene1735 2.44e-07 53.5 COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XRTE@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8 k141_9134_2 1278309.KB907107_gene1736 6.54e-117 348.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XIEK@135619|Oceanospirillales 135619|Oceanospirillales K Flagellar regulatory protein FleQ - - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k141_6339_1 1123360.thalar_00948 4.98e-210 602.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_18199_1 395493.BegalDRAFT_2635 3.37e-129 382.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,45ZW6@72273|Thiotrichales 72273|Thiotrichales J ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_773_1 1120999.JONM01000008_gene1925 1.69e-125 384.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,2KPEY@206351|Neisseriales 206351|Neisseriales K Tex-like protein N-terminal domain protein yhgF - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k141_4247_1 225937.HP15_2850 2.39e-05 44.3 2ASWM@1|root,31IC3@2|Bacteria,1N1F9@1224|Proteobacteria,1S798@1236|Gammaproteobacteria,46788@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3010) SO2839 - - - - - - - - - - - DUF3010 k141_4247_2 1288826.MSNKSG1_10518 3.61e-71 214.0 COG3012@1|root,COG3012@2|Bacteria,1N1DD@1224|Proteobacteria,1S8TK@1236|Gammaproteobacteria,468JD@72275|Alteromonadaceae 1236|Gammaproteobacteria S SEC-C motif - - - - - - - - - - - - SEC-C k141_4247_3 1288826.MSNKSG1_10513 8.97e-138 391.0 COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,1SCMX@1236|Gammaproteobacteria,4687I@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1278 Cold shock proteins - - - - - - - - - - - - CSD,DUF1294 k141_4247_4 1479237.JMLY01000001_gene3345 8.75e-36 124.0 COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,1S6EH@1236|Gammaproteobacteria,467ZF@72275|Alteromonadaceae 1236|Gammaproteobacteria S MOSC domain - - - - - - - - - - - - MOSC k141_19590_1 1288826.MSNKSG1_06288 1.46e-196 548.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,4643H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_19590_2 1288826.MSNKSG1_06283 3.52e-94 275.0 COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,1SCC5@1236|Gammaproteobacteria,46CGA@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442 k141_19590_3 1288826.MSNKSG1_06278 3.65e-61 189.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria,467VW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_3589_2 391593.RCCS2_12109 2.35e-22 92.4 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,2P168@2433|Roseobacter 28211|Alphaproteobacteria H Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA k141_16829_1 1229780.BN381_100166 0.00017 50.1 COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,3UW7I@52018|unclassified Actinobacteria (class) 201174|Actinobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C k141_1482_1 1408418.JNJH01000004_gene1980 1.51e-19 90.1 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,2JPDE@204441|Rhodospirillales 204441|Rhodospirillales S AFG1-like ATPase - - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_1482_2 1121028.ARQE01000002_gene1625 5.22e-09 56.6 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,2PKND@255475|Aurantimonadaceae 28211|Alphaproteobacteria S Patatin-like phospholipase rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_9150_1 1288826.MSNKSG1_11433 7.26e-103 321.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,468WP@72275|Alteromonadaceae 1236|Gammaproteobacteria I membrane-associated protein lssY - - ko:K03975 - - - - ko00000 - - - LssY_C,PAP2,SNARE_assoc k141_9150_2 925775.XVE_5096 3.61e-79 269.0 COG2199@1|root,COG2200@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,1MXTB@1224|Proteobacteria,1RMB5@1236|Gammaproteobacteria,1X4HH@135614|Xanthomonadales 135614|Xanthomonadales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - EAL,GAF,GGDEF k141_19601_1 1123057.P872_01780 1.97e-114 358.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia 976|Bacteroidetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 k141_14751_1 1121875.KB907550_gene636 2.3e-65 217.0 COG2015@1|root,COG2015@2|Bacteria,4NJE2@976|Bacteroidetes 976|Bacteroidetes Q Alkyl sulfatase dimerisation - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B k141_11952_1 1288826.MSNKSG1_18190 1.01e-150 426.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,466SM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_11952_2 1288826.MSNKSG1_18185 2.29e-119 340.0 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,468KM@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yqiB - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_11952_3 1288826.MSNKSG1_18180 3.45e-143 404.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,4670F@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3126 NUDIX k141_11952_4 1288826.MSNKSG1_18175 0.0 1263.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,465SM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c45100 ThiC-associated,ThiC_Rad_SAM k141_11952_5 1288826.MSNKSG1_18170 1.88e-307 840.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,46448@72275|Alteromonadaceae 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_11952_6 1288826.MSNKSG1_18165 5.35e-287 785.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,464WA@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1519 3-deoxy-D-manno-octulosonic-acid transferase waaA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417 Glycos_transf_1,Glycos_transf_N k141_11952_7 1288826.MSNKSG1_18160 5.77e-208 574.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,4653E@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_11952_8 1288826.MSNKSG1_18155 4.25e-219 605.0 COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,1S53F@1236|Gammaproteobacteria,4682W@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 k141_11952_9 1288826.MSNKSG1_18150 3.32e-54 179.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,465ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase waaG - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_11285_1 1121935.AQXX01000128_gene1844 3.11e-16 77.8 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,1XKXW@135619|Oceanospirillales 135619|Oceanospirillales M Identified by match to PFAM protein family HMMPF00534 InterPro Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_11285_2 314278.NB231_08420 2.44e-22 98.2 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k141_12649_1 1278309.KB907102_gene5 2.27e-127 368.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1XIBG@135619|Oceanospirillales 135619|Oceanospirillales M Polysaccharide biosynthesis protein - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k141_8459_1 1288826.MSNKSG1_09343 2.18e-60 189.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,465T7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_8459_2 1288826.MSNKSG1_09338 2.75e-98 292.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) epmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 k141_4952_1 1288826.MSNKSG1_06988 1e-182 539.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,46439@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_4952_2 1288826.MSNKSG1_06983 5.84e-71 223.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretory pathway component ExeA - - - - - - - - - - - - AAA_22,OmpA k141_2174_1 529818.AMSG_12443T0 1.72e-83 274.0 COG2217@1|root,KOG0207@2759|Eukaryota 2759|Eukaryota P cation-transporting ATPase activity - - - - - - - - - - - - E1-E2_ATPase,Hydrolase k141_17498_1 1288826.MSNKSG1_05461 4.62e-45 160.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,463XS@72275|Alteromonadaceae 1236|Gammaproteobacteria T GAF domain - - - - - - - - - - - - CZB,EAL,GAF,GAF_2,GGDEF,Hemerythrin,PAS_4,PAS_9,Protoglobin k141_17498_2 1415754.JQMK01000006_gene3717 4.71e-96 285.0 COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria,1T1HV@1236|Gammaproteobacteria,46D48@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ybbO GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - - - - - - - - - - adh_short k141_71_1 159450.NH14_12175 8.59e-59 192.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,1K06R@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_71_2 765911.Thivi_0099 1.23e-99 300.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_20345_1 55601.VANGNB10_cI2099c 1.47e-49 177.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales 135623|Vibrionales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD recD - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 k141_6362_1 317936.Nos7107_2057 3.68e-78 243.0 COG1723@1|root,COG1723@2|Bacteria,1G40I@1117|Cyanobacteria,1HMQ6@1161|Nostocales 1117|Cyanobacteria S PFAM Uncharacterised ACR, YagE family COG1723 - - - - - - - - - - - - DUF155 k141_6362_2 1380355.JNIJ01000012_gene1140 2.24e-52 175.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2TS1B@28211|Alphaproteobacteria,3JSVW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain gstch1 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_6362_4 631362.Thi970DRAFT_00790 3.71e-11 62.4 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1WWVB@135613|Chromatiales 135613|Chromatiales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 k141_4269_1 1288826.MSNKSG1_08798 2.42e-160 473.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,4662T@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1596 Periplasmic protein involved in polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB k141_19602_1 1232683.ADIMK_1592 1.6e-12 66.6 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD k141_19602_2 1122194.AUHU01000002_gene2459 5.79e-35 125.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,468BK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Modulates RecA activity recX GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_21672_1 1046714.AMRX01000006_gene2492 3.49e-46 157.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,465G5@72275|Alteromonadaceae 1236|Gammaproteobacteria S amidohydrolase aguB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_21672_2 1121937.AUHJ01000006_gene2416 8.71e-60 191.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,4674J@72275|Alteromonadaceae 1236|Gammaproteobacteria S aspartyl protease orf - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas k141_21672_3 1411685.U062_01059 1.08e-13 70.9 COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1J68V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - k141_9151_1 317025.Tcr_0071 4.94e-19 93.6 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,460JF@72273|Thiotrichales 72273|Thiotrichales S Oxygen tolerance - - - - - - - - - - - - BatD k141_1483_1 530564.Psta_1051 1.1e-65 222.0 COG1611@1|root,COG1989@1|root,COG1611@2|Bacteria,COG1989@2|Bacteria,2IZCH@203682|Planctomycetes 203682|Planctomycetes NOU Possible lysine decarboxylase - - - - - - - - - - - - Lysine_decarbox k141_17499_1 1122180.Lokhon_01999 9.29e-37 132.0 COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2TQUF@28211|Alphaproteobacteria,2P83H@245186|Loktanella 28211|Alphaproteobacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS k141_17499_2 1121479.AUBS01000001_gene3445 3.62e-26 104.0 COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,2TU1M@28211|Alphaproteobacteria 28211|Alphaproteobacteria V (ABC) transporter - - - - - - - - - - - - - k141_18922_1 1249627.D779_4118 6.1e-123 370.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_21064_1 377629.TERTU_1657 1.22e-38 134.0 COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,1T190@1236|Gammaproteobacteria,2PPWU@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Type VI secretion system, VipA, VC_A0107 or Hcp2 impB - - ko:K11901 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VipA k141_21064_2 1122194.AUHU01000003_gene2291 2.92e-43 154.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,464MV@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria impC - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_8460_2 2340.JV46_02960 1.37e-82 254.0 COG0398@1|root,COG0607@1|root,COG0398@2|Bacteria,COG0607@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P SNARE associated Golgi protein ydjX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Rhodanese,SNARE_assoc k141_4953_2 177437.HRM2_33290 4.74e-18 81.6 COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria,2MKJH@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - - - - - - - - - - DctQ k141_8461_1 388739.RSK20926_18707 1.16e-16 77.8 COG1226@1|root,COG1226@2|Bacteria,1NH49@1224|Proteobacteria,2UENB@28211|Alphaproteobacteria,2P3H5@2433|Roseobacter 28211|Alphaproteobacteria P COG1226 Kef-type K transport systems - - - - - - - - - - - - Ion_trans_2 k141_4954_2 1415756.JQMY01000001_gene1549 4.03e-16 76.6 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2PCE8@252301|Oceanicola 28211|Alphaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase k141_3592_1 1443111.JASG01000004_gene3590 3.7e-79 249.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2TQUH@28211|Alphaproteobacteria,3ZVG4@60136|Sulfitobacter 28211|Alphaproteobacteria S Flavin containing amine oxidoreductase - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase k141_8462_1 1150469.RSPPHO_03274 5.36e-18 79.3 2DTV2@1|root,33MS7@2|Bacteria,1NKAB@1224|Proteobacteria 2|Bacteria - - - - - - - - - - - - - - - k141_11953_1 545276.KB898725_gene579 0.000596 42.0 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_11953_2 96561.Dole_2006 4.65e-63 207.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WM2C@28221|Deltaproteobacteria,2MIPY@213118|Desulfobacterales 28221|Deltaproteobacteria S Pfam:UPF0118 - - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_14752_1 1298593.TOL_2459 2.42e-69 221.0 COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XKAP@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_16830_1 1278309.KB907100_gene1864 9.94e-144 412.0 COG0671@1|root,COG0671@2|Bacteria,1NAJ7@1224|Proteobacteria,1SDY6@1236|Gammaproteobacteria,1XKS9@135619|Oceanospirillales 135619|Oceanospirillales I Acid phosphatase homologues - - - - - - - - - - - - PAP2 k141_8463_1 1502770.JQMG01000001_gene2068 1.32e-50 182.0 COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KKZP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM EAL domain protein - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_9 k141_4956_1 1122201.AUAZ01000001_gene2474 1.01e-122 365.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,46AGN@72275|Alteromonadaceae 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_16831_1 425104.Ssed_1293 2.51e-43 145.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,2QBKF@267890|Shewanellaceae 1236|Gammaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3360 YgbB k141_8464_1 227377.CBU_1509 4.65e-41 151.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1JD0N@118969|Legionellales 118969|Legionellales J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_19605_2 556261.HMPREF0240_03236 1.09e-07 55.1 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V106@1239|Firmicutes,24DQP@186801|Clostridia,36VJB@31979|Clostridiaceae 186801|Clostridia K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18,HTH_AraC,Response_reg k141_16113_1 1163617.SCD_n01479 9.28e-209 600.0 COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,2W1SU@28216|Betaproteobacteria 28216|Betaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k141_16833_1 1278309.KB907100_gene1938 2.55e-108 327.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XH69@135619|Oceanospirillales 135619|Oceanospirillales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_4957_1 472759.Nhal_3892 5.12e-167 498.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_14753_1 1049564.TevJSym_ai00730 3.54e-85 256.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1J5UT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_14753_2 1163617.SCD_n01056 2.16e-87 269.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria 28216|Betaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_2878_1 1288826.MSNKSG1_12192 9.1e-302 823.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,46537@72275|Alteromonadaceae 1236|Gammaproteobacteria I Biotin carboxylase accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iSF_1195.SF3294 Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_2878_2 1288826.MSNKSG1_12197 6.04e-217 598.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,4650B@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_2878_3 1288826.MSNKSG1_12202 5.42e-232 644.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,46705@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 k141_2878_4 1288826.MSNKSG1_12207 1.71e-240 660.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,464KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_2878_5 1288826.MSNKSG1_12212 1.12e-63 195.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,468HA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 k141_2878_6 1288826.MSNKSG1_12217 0.0 1026.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS k141_2878_7 1288826.MSNKSG1_12222 2.17e-303 828.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4649C@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the GARS family purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 GARS_A,GARS_C,GARS_N k141_5118_2 105559.Nwat_0566 2.13e-48 156.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1WYHG@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_19106_1 713586.KB900536_gene579 1.83e-66 213.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Squalene/phytoene synthase - - - - - - - - - - - - SQS_PSY k141_16246_1 344747.PM8797T_23971 2.23e-106 321.0 COG0389@1|root,COG0389@2|Bacteria,2IZ2I@203682|Planctomycetes 203682|Planctomycetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_2301_1 1423321.AS29_05280 0.000274 45.1 COG1057@1|root,COG1057@2|Bacteria,1V2XS@1239|Firmicutes,4HFV3@91061|Bacilli,1ZDMK@1386|Bacillus 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like k141_2301_2 1158165.KB898880_gene1517 8.68e-43 144.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1WYQV@135613|Chromatiales 135613|Chromatiales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_243_2 426114.THI_0897 2.62e-35 129.0 COG1651@1|root,COG1651@2|Bacteria,1NEFD@1224|Proteobacteria,2VKFR@28216|Betaproteobacteria 28216|Betaproteobacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbG - - ko:K03805 - - - - ko00000,ko03110 - - - Thioredoxin_2 k141_7217_1 1188256.BASI01000002_gene3599 5.18e-27 108.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3FDS6@34008|Rhodovulum 28211|Alphaproteobacteria T Sigma-54 interaction domain dctD - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_7217_2 644107.SL1157_2991 2.01e-33 129.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4N9VH@97050|Ruegeria 28211|Alphaproteobacteria T Signal transduction histidine kinase dctB - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1,dCache_3 k141_16985_1 399739.Pmen_1462 9.84e-48 162.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1YEYB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T HDOD domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_3056_1 1502851.FG93_00264 3.47e-82 255.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,3JSMU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Elongator protein 3, MiaB family, Radical SAM MA20_42330 - - - - - - - - - - - Radical_SAM k141_21212_1 644076.SCH4B_3436 1.28e-124 383.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,4NAKE@97050|Ruegeria 28211|Alphaproteobacteria D Ftsk_gamma ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_21878_1 1288826.MSNKSG1_05898 6.75e-40 146.0 COG0369@1|root,COG3182@1|root,COG0369@2|Bacteria,COG3182@2|Bacteria,1MWYV@1224|Proteobacteria,1RY05@1236|Gammaproteobacteria,465H6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Flavodoxin cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,FAD_binding_6,Flavodoxin_1,NAD_binding_1,PepSY_TM k141_21878_2 1288826.MSNKSG1_05893 3.85e-118 338.0 29N8T@1|root,3096N@2|Bacteria,1RJCI@1224|Proteobacteria,1S62U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tat pathway signal protein - - - - - - - - - - - - DUF2271 k141_21878_3 1288826.MSNKSG1_05888 2.19e-82 244.0 COG5591@1|root,COG5591@2|Bacteria,1N6RP@1224|Proteobacteria,1SDXA@1236|Gammaproteobacteria,4694H@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 k141_21878_4 1288826.MSNKSG1_05883 8.76e-130 370.0 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1SYUC@1236|Gammaproteobacteria,46ABI@72275|Alteromonadaceae 1236|Gammaproteobacteria K response regulator - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_16247_1 396588.Tgr7_0170 3.62e-41 149.0 COG1524@1|root,COG1524@2|Bacteria,1R2II@1224|Proteobacteria,1RQDZ@1236|Gammaproteobacteria,1X2CP@135613|Chromatiales 135613|Chromatiales S PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_19755_1 1288826.MSNKSG1_09133 1.51e-66 213.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,4643J@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_19755_2 1288826.MSNKSG1_09128 3.05e-179 498.0 COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,466RK@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylas_C,SpoU_methylase k141_17695_1 1461694.ATO9_05410 1.73e-129 393.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2PCWG@252301|Oceanicola 28211|Alphaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k141_11428_1 1198232.CYCME_1988 2.42e-49 169.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,460J5@72273|Thiotrichales 72273|Thiotrichales M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 k141_19107_1 1121127.JAFA01000024_gene7879 1.52e-13 73.6 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1K1RF@119060|Burkholderiaceae 28216|Betaproteobacteria M Belongs to the peptidase S1C family mucD - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_10730_1 1288826.MSNKSG1_07568 2.01e-70 217.0 COG1309@1|root,COG1309@2|Bacteria,1RJ63@1224|Proteobacteria,1S8HV@1236|Gammaproteobacteria,46CGE@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N k141_10730_2 1288826.MSNKSG1_07563 1.81e-216 597.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,464FD@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_10730_3 1288826.MSNKSG1_07558 4.49e-157 441.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,467N7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_10730_4 1288826.MSNKSG1_07553 3.11e-45 146.0 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,46912@72275|Alteromonadaceae 1236|Gammaproteobacteria P protein, possibly involved in nitrogen fixation ccoS - - - - - - - - - - - FixS k141_10730_5 1288826.MSNKSG1_07548 0.0 1553.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase k141_10730_6 1288826.MSNKSG1_07543 1.41e-123 352.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,468BX@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria ccoH - - ko:K09926 - - - - ko00000 - - - FixH k141_10730_7 1288826.MSNKSG1_07538 0.0 908.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4650C@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0348 Polyferredoxin ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_10730_8 1288826.MSNKSG1_07533 4.12e-223 613.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,464W3@72275|Alteromonadaceae 1236|Gammaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - iJN746.PP_4253 Cytochrome_CBB3,FixP_N k141_10730_9 1288826.MSNKSG1_07528 8.34e-37 124.0 COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,468WV@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG4736 Cbb3-type cytochrome oxidase, subunit 3 ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_10730_10 1288826.MSNKSG1_07523 1.12e-146 412.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,464XG@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_10730_11 1288826.MSNKSG1_07518 0.0 959.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,4654T@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_10730_12 1288826.MSNKSG1_07513 1.1e-37 132.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,466TR@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6,DLH k141_1663_1 1288826.MSNKSG1_05938 1.4e-220 615.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,468A1@72275|Alteromonadaceae 1236|Gammaproteobacteria G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_1663_2 1288826.MSNKSG1_05933 3.44e-79 235.0 2DGSQ@1|root,2ZX5S@2|Bacteria,1P72E@1224|Proteobacteria,1SVW5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ k141_1663_3 1288826.MSNKSG1_05928 1.02e-88 282.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,4662I@72275|Alteromonadaceae 1236|Gammaproteobacteria G Protein of unknown function (DUF3417) - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_7218_1 1417296.U879_09635 5.11e-41 149.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_7218_2 744979.R2A130_3419 1.63e-50 167.0 COG1802@1|root,COG1802@2|Bacteria,1MXNF@1224|Proteobacteria,2U1PK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Regulatory protein GntR HTH MA20_15070 - - - - - - - - - - - FCD,GntR k141_5119_1 1286106.MPL1_02933 7.16e-09 57.8 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,460F8@72273|Thiotrichales 72273|Thiotrichales S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 k141_5119_2 314345.SPV1_05083 1.12e-21 90.9 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_5119_3 1121129.KB903360_gene3146 6.72e-16 75.9 COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,2FMXN@200643|Bacteroidia,22YQN@171551|Porphyromonadaceae 976|Bacteroidetes S HAD hydrolase, family IA, variant 3 - GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104 ko:K07025,ko:K20866,ko:K21063 ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120 M00125 R00947,R07280 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 - - - HAD_2,Hydrolase k141_964_1 948565.AFFP02000004_gene750 7.45e-76 241.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1Y6UG@135625|Pasteurellales 135625|Pasteurellales F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_13502_1 439497.RR11_2360 7.57e-122 356.0 COG1638@1|root,COG1638@2|Bacteria,1NJX4@1224|Proteobacteria,2U0XM@28211|Alphaproteobacteria,4NBT3@97050|Ruegeria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_15607_1 936136.ARRT01000006_gene1782 1.86e-69 221.0 COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,2UDR1@28211|Alphaproteobacteria,4BHN3@82115|Rhizobiaceae 28211|Alphaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k141_19775_1 396588.Tgr7_2123 8.31e-151 443.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_12817_1 1278309.KB907102_gene24 5.09e-46 150.0 2E8F1@1|root,332TD@2|Bacteria,1NBB5@1224|Proteobacteria,1SFEQ@1236|Gammaproteobacteria,1XMSP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_12817_2 1278309.KB907102_gene25 1.72e-239 665.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XI8P@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd2 - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_12817_3 1278309.KB907102_gene26 1.4e-151 439.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XI59@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_9293_1 713586.KB900536_gene2528 1.74e-123 365.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_4486_1 1313172.YM304_02120 3.08e-18 93.6 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CMUZ@84992|Acidimicrobiia 84992|Acidimicrobiia KLT Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase k141_5130_2 396588.Tgr7_2268 1.06e-91 276.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales 135613|Chromatiales S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_5850_1 1121949.AQXT01000002_gene1129 1.31e-17 82.4 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2U20B@28211|Alphaproteobacteria,43X1N@69657|Hyphomonadaceae 28211|Alphaproteobacteria P CorA-like Mg2+ transporter protein - - - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_16265_1 288000.BBta_p0098 1.35e-12 67.4 COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,2TVIW@28211|Alphaproteobacteria,3JXU9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Glucodextranase, domain N cga - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glucodextran_N,Glyco_hydro_15 k141_16265_2 580332.Slit_0395 4.62e-82 258.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,44V6S@713636|Nitrosomonadales 28216|Betaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_7244_1 1288826.MSNKSG1_02268 0.0 1007.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1R8MU@1224|Proteobacteria,1S01I@1236|Gammaproteobacteria,469GR@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GGDEF k141_965_1 1461693.ATO10_00610 3.06e-76 237.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2TT2U@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_14202_2 1278309.KB907109_gene3296 9.47e-71 220.0 COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,1RNFR@1236|Gammaproteobacteria,1XH35@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K02521 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_3079_1 396588.Tgr7_2124 4.83e-37 147.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales 135613|Chromatiales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_10753_1 1026882.MAMP_01569 4.33e-86 277.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein Ccs1 ResB - - - ko:K07399 - - - - ko00000 - - - ResB k141_16266_1 633131.TR2A62_2141 2.82e-44 157.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_5851_3 1185652.USDA257_c31360 1.99e-06 50.1 COG3473@1|root,COG3473@2|Bacteria,1RA2D@1224|Proteobacteria,2U5UC@28211|Alphaproteobacteria,4BCMX@82115|Rhizobiaceae 28211|Alphaproteobacteria Q Asp Glu hydantoin racemase eutA - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race k141_9980_1 1288826.MSNKSG1_02018 2.02e-136 388.0 COG4705@1|root,COG4705@2|Bacteria,1RFXY@1224|Proteobacteria 1224|Proteobacteria S Repeat of Unknown Function (DUF347) - - - - - - - - - - - - - k141_7245_1 391593.RCCS2_07599 6.07e-39 134.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2P24R@2433|Roseobacter 28211|Alphaproteobacteria L COG2818 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k141_7245_2 388399.SSE37_20097 8.54e-12 65.9 COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,2TT4R@28211|Alphaproteobacteria 28211|Alphaproteobacteria T EAL domain yfgF - - - - - - - - - - - EAL k141_14203_1 521045.Kole_0885 5.57e-24 97.8 COG0071@1|root,COG0071@2|Bacteria,2GDCG@200918|Thermotogae 200918|Thermotogae O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_7975_1 568706.BN118_0058 2.07e-24 104.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,3T227@506|Alcaligenaceae 28216|Betaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_7975_2 1049564.TevJSym_aq00120 1.82e-52 167.0 2F88A@1|root,340MG@2|Bacteria,1NXS1@1224|Proteobacteria,1SQ1P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - MazG k141_7975_3 379731.PST_0008 1.47e-65 206.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1Z1CQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria G D,D-heptose 1,7-bisphosphate phosphatase gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iJN746.PP_0059 Hydrolase_like k141_16267_1 1283300.ATXB01000001_gene2145 7.33e-51 171.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RQZ9@1236|Gammaproteobacteria,1XG3E@135618|Methylococcales 135618|Methylococcales E Amino-transferase class IV - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_966_2 765911.Thivi_0660 1.89e-51 163.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales 135613|Chromatiales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k141_966_3 572477.Alvin_1912 1.34e-15 73.9 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1WYH1@135613|Chromatiales 135613|Chromatiales S PFAM FxsA cytoplasmic membrane protein - - - ko:K07113 - - - - ko00000 - - - FxsA k141_19777_1 1298593.TOL_3367 1.53e-54 185.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1XHJE@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k141_9981_1 87626.PTD2_17690 6.49e-25 95.5 COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,2Q3K5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09794 - - - - ko00000 - - - DUF465 k141_10754_1 298386.PBPRB0647 1.13e-57 188.0 COG1143@1|root,COG1143@2|Bacteria,1QWN1@1224|Proteobacteria 1224|Proteobacteria C 4Fe-4S binding domain - - - ko:K02573 - - - - ko00000 - - - Fer4 k141_6496_1 1453501.JELR01000001_gene2245 1.1e-57 195.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4648E@72275|Alteromonadaceae 1236|Gammaproteobacteria Q multicopper oxidases pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_6496_2 1208321.D104_14680 1.37e-30 116.0 COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria,1XK7B@135619|Oceanospirillales 135619|Oceanospirillales P protein involved in copper resistance pcoB - - ko:K07233 - - - - ko00000 - - - CopB k141_14204_1 765913.ThidrDRAFT_0378 6.21e-32 120.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 k141_7976_1 1122201.AUAZ01000023_gene3016 1.87e-76 236.0 COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,1RPF3@1236|Gammaproteobacteria,468GI@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K19338 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_1691_1 1202962.KB907158_gene3736 2.78e-30 113.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k141_261_1 745411.B3C1_17197 1.48e-09 61.2 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1J715@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl k141_18535_2 391615.ABSJ01000037_gene910 6.69e-36 126.0 COG0664@1|root,COG0664@2|Bacteria,1N4C9@1224|Proteobacteria 1224|Proteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_5326_1 314345.SPV1_11231 5.24e-92 276.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria 1224|Proteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - iYL1228.KPN_03461 BacA k141_21382_1 159749.K0T654 7.82e-06 53.9 2DG6W@1|root,2S5TV@2759|Eukaryota 2759|Eukaryota S Sulphur transport - - - - - - - - - - - - Sulf_transp k141_3262_1 1278309.KB907101_gene599 1.58e-138 404.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1XJ2H@135619|Oceanospirillales 135619|Oceanospirillales T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9 k141_3262_2 1278309.KB907101_gene598 9.06e-26 99.8 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XJ8Q@135619|Oceanospirillales 135619|Oceanospirillales T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_450_1 225849.swp_3095 2.74e-43 160.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,2QABE@267890|Shewanellaceae 1236|Gammaproteobacteria T histidine kinase HAMP region domain protein - - 2.7.13.3 ko:K07641 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_2511_1 666685.R2APBS1_3951 9.29e-74 230.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1X4YZ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_17889_1 1370120.AUWR01000008_gene386 2.02e-27 111.0 COG0546@1|root,COG0546@2|Bacteria,2HFGX@201174|Actinobacteria,2335N@1762|Mycobacteriaceae 201174|Actinobacteria S IA, variant 1 nt5e GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_17889_2 1232683.ADIMK_3883 2.34e-155 441.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1S18F@1236|Gammaproteobacteria,46AQB@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate bcpA GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008807,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016772,GO:0016780,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114 4.1.1.3 ko:K01003 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000 - - - PEP_mutase k141_17889_3 1232683.ADIMK_3884 9.21e-45 154.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1T04U@1236|Gammaproteobacteria,469W1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_16434_1 748280.NH8B_0112 4.01e-150 454.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_16434_2 420324.KI911998_gene8158 9.09e-31 116.0 COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,2U7WC@28211|Alphaproteobacteria 28211|Alphaproteobacteria I CDP-archaeol synthase - - 2.7.7.67 ko:K19664 ko00564,map00564 - R08966 RC00002 ko00000,ko00001,ko01000 - - - CarS-like k141_19303_2 314278.NB231_11604 2.02e-155 449.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_7402_1 1232683.ADIMK_1426 4.42e-86 276.0 COG0404@1|root,COG3665@1|root,COG0404@2|Bacteria,COG3665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C k141_3890_1 675806.VII_001003 7.54e-20 92.4 COG2199@1|root,COG2199@2|Bacteria,1R5EK@1224|Proteobacteria,1SNTR@1236|Gammaproteobacteria,1XUDU@135623|Vibrionales 135623|Vibrionales T Sensory box GGDEF family - - - - - - - - - - - - GGDEF,PAS_9,dCache_1 k141_13016_3 349521.HCH_02987 5.8e-39 144.0 COG4783@1|root,COG4783@2|Bacteria,1NSV0@1224|Proteobacteria,1SKTU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S chaperone-mediated protein folding - - - - - - - - - - - - - k141_15810_1 96561.Dole_0620 3.55e-40 151.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MIJD@213118|Desulfobacterales 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind k141_13701_1 396588.Tgr7_0529 1.81e-62 197.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1WWEP@135613|Chromatiales 135613|Chromatiales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro k141_20662_2 1121935.AQXX01000085_gene5322 1.32e-59 184.0 COG1396@1|root,COG1396@2|Bacteria,1QVB0@1224|Proteobacteria 1224|Proteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 k141_18536_1 269799.Gmet_3429 7.25e-75 235.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,42RYH@68525|delta/epsilon subdivisions,2WNT0@28221|Deltaproteobacteria,43VVX@69541|Desulfuromonadales 28221|Deltaproteobacteria L Transposase - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_12325_2 379731.PST_3311 4.25e-28 112.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1YZPB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_5327_1 472175.EL18_03388 1.32e-102 305.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,43HSN@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase hpcE - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_1833_1 1288826.MSNKSG1_00046 2.99e-144 406.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,465S7@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_1833_3 1288826.MSNKSG1_00056 1.09e-173 485.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,464CG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Cytochrome C1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_1833_4 1288826.MSNKSG1_00061 5.96e-150 421.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,464JH@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase sspA GO:0001000,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0008150,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0042594,GO:0043175,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_1833_5 1288826.MSNKSG1_00066 9.01e-92 269.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,467R0@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2969 Stringent starvation protein B sspB GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_15052_1 713587.THITH_02840 1.88e-60 198.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales 135613|Chromatiales S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 k141_15052_2 187272.Mlg_2703 2.4e-65 218.0 COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,1S0NV@1236|Gammaproteobacteria,1WXDD@135613|Chromatiales 135613|Chromatiales CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Glutaredoxin k141_10176_1 472759.Nhal_3704 8.84e-120 352.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_10176_2 323261.Noc_2567 8.04e-133 390.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales 135613|Chromatiales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_17890_1 1121374.KB891585_gene2241 3.24e-07 50.4 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SD3Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7403_1 713587.THITH_02785 8.28e-85 260.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1WWGF@135613|Chromatiales 135613|Chromatiales F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_22046_1 998674.ATTE01000001_gene495 6.1e-138 412.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,45ZXG@72273|Thiotrichales 72273|Thiotrichales S ABC transporter - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_19304_1 153948.NAL212_0715 3.68e-07 50.4 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,3723W@32003|Nitrosomonadales 28216|Betaproteobacteria E TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - - - - - - - - - - HAD k141_19304_2 264198.Reut_A0655 4.26e-23 99.4 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,1K1E7@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_15811_1 1278309.KB907101_gene454 2.85e-112 340.0 COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,1RPF4@1236|Gammaproteobacteria,1XRH8@135619|Oceanospirillales 135619|Oceanospirillales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_452_2 1485544.JQKP01000002_gene1413 8.71e-05 45.8 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 k141_21383_1 1278309.KB907099_gene2431 7.37e-80 246.0 COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,1RRVB@1236|Gammaproteobacteria,1XJFH@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - - k141_13018_1 2340.JV46_07570 5.85e-92 273.0 COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1J6R4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 k141_17891_1 317025.Tcr_1975 3.94e-14 72.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,461PA@72273|Thiotrichales 72273|Thiotrichales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_17891_2 443152.MDG893_14023 1.98e-06 49.3 COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,46CF3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_15053_1 1112217.PPL19_21875 6.23e-26 107.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_20663_1 717772.THIAE_02680 7.33e-28 115.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,462F9@72273|Thiotrichales 72273|Thiotrichales S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_4642_1 379731.PST_2975 2.45e-100 299.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1Z1FE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_4642_2 637905.SVI_2356 2.66e-90 273.0 COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,2Q8YK@267890|Shewanellaceae 1236|Gammaproteobacteria J Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 k141_4642_3 1123279.ATUS01000002_gene255 6.07e-65 208.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1J57X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_10927_1 870187.Thini_2509 3.67e-106 324.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_2513_1 416269.APL_1681 3.1e-57 199.0 arCOG06613@1|root,2Z7VT@2|Bacteria,1MVIU@1224|Proteobacteria,1RZ5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AIPR protein - - - - - - - - - - - - AIPR k141_18537_1 1163617.SCD_n02789 4.48e-48 176.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria 28216|Betaproteobacteria CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_2,Thioredoxin_7 k141_18537_2 85643.Tmz1t_3914 3.91e-08 52.4 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales 206389|Rhodocyclales P protein involved in tolerance to divalent cations cutA1 - - ko:K03926 - - - - ko00000 - - - CutA1 k141_3891_1 1122201.AUAZ01000036_gene1228 8.96e-87 270.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,4645M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Reductase C-terminal alkT - 1.18.1.1,1.18.1.3 ko:K00529,ko:K21738 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C k141_15812_1 400668.Mmwyl1_2421 3.62e-81 255.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XI0Q@135619|Oceanospirillales 135619|Oceanospirillales P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_10177_2 1123288.SOV_2c08680 1.04e-12 67.4 COG1586@1|root,COG1586@2|Bacteria,1TQ7S@1239|Firmicutes,4H2YX@909932|Negativicutes 909932|Negativicutes H Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_5329_1 1238182.C882_3998 5.76e-14 72.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,2JQUV@204441|Rhodospirillales 204441|Rhodospirillales S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb k141_21402_1 1288826.MSNKSG1_04236 1.81e-90 291.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0474 Cation transport ATPase - - 3.6.3.6 ko:K01535,ko:K12955 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.24,3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_17908_1 1469607.KK073768_gene3290 7.51e-98 320.0 COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJVE@1161|Nostocales 1117|Cyanobacteria Q COGs COG3321 Polyketide synthase modules and related protein - - - - - - - - - - - - Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt k141_15826_1 1288826.MSNKSG1_12107 3.24e-43 151.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464ZN@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases visC GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03184,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R06146,R08768,R08775 RC00046,RC01254 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_15826_2 1288826.MSNKSG1_12112 3.37e-308 840.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,464X1@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185,ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R04989,R08768,R08773 RC00046,RC02670 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066 FAD_binding_3 k141_15826_3 1288826.MSNKSG1_12117 0.0 898.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,464SX@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0006 Xaa-Pro aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k141_15826_4 1288826.MSNKSG1_12122 2.63e-135 384.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,4689M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0149 family ygfB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09895 - - - - ko00000 - - - UPF0149 k141_15826_5 1288826.MSNKSG1_12127 1.2e-39 131.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,4697N@72275|Alteromonadaceae 1236|Gammaproteobacteria S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - - k141_15826_6 1288826.MSNKSG1_12132 6.25e-60 185.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,468PG@72275|Alteromonadaceae 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k141_15826_7 1288826.MSNKSG1_12137 1.52e-153 431.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,467AN@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig k141_15826_9 1288826.MSNKSG1_12147 0.0 1000.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,46556@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2699 PALP,Thr_dehydrat_C k141_15826_10 1288826.MSNKSG1_12152 2.22e-158 444.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,46422@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_15826_11 1288826.MSNKSG1_12157 3.47e-266 729.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RQ5M@1236|Gammaproteobacteria,464GY@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_15826_12 1288826.MSNKSG1_12162 3.87e-127 361.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,4647K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iJN746.PP_0538,iPC815.YPO3521 Pyrophosphatase k141_476_1 1042375.AFPL01000038_gene1610 9.8e-82 250.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RR43@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively mhpB GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0008198,GO:0009056,GO:0009698,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019622,GO:0019748,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046271,GO:0046395,GO:0046435,GO:0046872,GO:0046914,GO:0047070,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.13.11.16,1.13.11.57 ko:K04099,ko:K05713 ko00360,ko00627,ko01120,ko01220,map00360,map00627,map01120,map01220 M00545 R03550,R04280,R04376,R06788,R09565 RC00233,RC00535,RC01140,RC01364,RC02567,RC02694 br01602,ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0349,iECO111_1330.ECO111_0384,iECO26_1355.ECO26_0384,iECSE_1348.ECSE_0373,iECW_1372.ECW_m0426,iEKO11_1354.EKO11_3494,iEcE24377_1341.EcE24377A_0372,iEcHS_1320.EcHS_A0412,iWFL_1372.ECW_m0426 LigB k141_476_2 322710.Avin_15060 8.79e-113 334.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,1RMG8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase - - 1.14.14.12 ko:K16047 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R09819 RC00236 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_11598_1 1470593.BW43_05292 8.82e-72 224.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_11598_2 491952.Mar181_2951 2.68e-138 395.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XIJB@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k141_11598_3 400668.Mmwyl1_3695 6.4e-173 488.0 COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,1RS0Y@1236|Gammaproteobacteria,1XJ30@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter glnP - - ko:K02029,ko:K10037 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1 k141_11598_4 400668.Mmwyl1_3696 4.31e-154 437.0 COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZ89@1236|Gammaproteobacteria,1XI3B@135619|Oceanospirillales 135619|Oceanospirillales ET PFAM Extracellular solute-binding protein, family 3 - - - ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - SBP_bac_3 k141_11598_5 400668.Mmwyl1_3697 6.85e-229 637.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1XIWE@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Cys Met metabolism - - 2.5.1.48,4.4.1.1 ko:K01739,ko:K01758 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP k141_11598_6 1208321.D104_11060 7.43e-148 424.0 COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,1RS8M@1236|Gammaproteobacteria,1XK6T@135619|Oceanospirillales 135619|Oceanospirillales H homocysteine S-methyltransferase - - - - - - - - - - - - S-methyl_trans k141_13052_1 631362.Thi970DRAFT_03839 1.26e-56 185.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1WYUF@135613|Chromatiales 135613|Chromatiales E Asparaginase - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 k141_13052_2 631362.Thi970DRAFT_03838 3.45e-37 135.0 COG2232@1|root,COG2232@2|Bacteria 2|Bacteria V ATP-grasp domain - - - - - - - - - - - - ATP-grasp_3 k141_19939_1 1121374.KB891585_gene1949 1.52e-14 73.2 COG1253@1|root,COG1253@2|Bacteria,1N0IQ@1224|Proteobacteria,1RY1D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF21 - - - - - - - - - - - - DUF21 k141_19939_2 314345.SPV1_00967 2e-39 147.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 - - - ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,PTS_EIIA_2 k141_1853_1 351746.Pput_4860 6.12e-57 183.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hemolysin iii yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_17170_1 985255.APHJ01000021_gene1361 3.66e-07 50.1 COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1I3YR@117743|Flavobacteriia,2P6WF@244698|Gillisia 976|Bacteroidetes O Glutaredoxin-like domain (DUF836) - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_17170_2 640081.Dsui_1801 9.11e-36 130.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VPQ9@28216|Betaproteobacteria,2M01K@206389|Rhodocyclales 206389|Rhodocyclales D ATPase MipZ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - CbiA k141_3914_1 671143.DAMO_0362 1.17e-71 225.0 COG2837@1|root,COG2837@2|Bacteria 2|Bacteria P iron assimilation dyp - - ko:K07223 - - - - ko00000 - - - Dyp_perox k141_15827_1 83406.HDN1F_16410 1.36e-64 212.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RMXA@1236|Gammaproteobacteria,1J4TC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C FAD binding domain dprE1 - - - - - - - - - - - ALO,FAD_binding_4 k141_6794_1 1278309.KB907102_gene93 1.29e-112 356.0 COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales 135619|Oceanospirillales D Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 k141_6794_2 1278309.KB907102_gene94 4.58e-76 229.0 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,1XKSJ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0225 family - - - ko:K09858 - - - - ko00000 - - - CW_binding_1,SEC-C k141_6794_3 1278309.KB907102_gene95 1.43e-310 851.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1XHYI@135619|Oceanospirillales 135619|Oceanospirillales L Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates sbcB - 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_6794_4 1278309.KB907102_gene96 5.61e-69 213.0 2B10W@1|root,31TE6@2|Bacteria,1QR41@1224|Proteobacteria,1RTXP@1236|Gammaproteobacteria,1XQHS@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6794_5 1278309.KB907102_gene97 1.92e-91 295.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XI12@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_15192_1 1278309.KB907104_gene960 7.42e-173 486.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XHR1@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_15192_2 1278309.KB907104_gene961 8.83e-145 421.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XI27@135619|Oceanospirillales 135619|Oceanospirillales G phosphomannomutase algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_13227_1 1123517.JOMR01000001_gene3 3.77e-17 75.9 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,461D2@72273|Thiotrichales 72273|Thiotrichales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_13227_2 1111732.AZOD01000005_gene837 1.23e-10 63.2 COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria 1224|Proteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_4839_1 32042.PstZobell_20358 7.39e-20 85.5 COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,1Z2RF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S integral membrane protein - - - - - - - - - - - - CopD k141_10405_2 754477.Q7C_2104 1.05e-50 171.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,461PX@72273|Thiotrichales 72273|Thiotrichales M phospholipase A1 - - 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - - PLA1 k141_11123_1 1278309.KB907106_gene1343 9.43e-48 156.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1XM73@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - TerB k141_11123_2 944435.AXAJ01000002_gene4622 7.81e-15 75.5 COG1846@1|root,COG1846@2|Bacteria,1N7BV@1224|Proteobacteria,2VU53@28216|Betaproteobacteria,1KFP8@119060|Burkholderiaceae 28216|Betaproteobacteria K PFAM regulatory protein, MarR marR_1 - - - - - - - - - - - MarR,MarR_2 k141_11123_3 2342.SOPEG_2933 3.33e-139 410.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria 1236|Gammaproteobacteria V multidrug resistance efflux pump emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_11123_4 1112217.PPL19_18712 6.63e-268 744.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_11123_5 88036.EFJ38637 4.01e-72 233.0 COG3491@1|root,KOG0143@2759|Eukaryota,37JSZ@33090|Viridiplantae,3GFF2@35493|Streptophyta 35493|Streptophyta Q Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N k141_11123_6 1122201.AUAZ01000002_gene1060 1.8e-214 598.0 COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria,465BU@72275|Alteromonadaceae 1236|Gammaproteobacteria S ABC transporter substrate-binding protein PnrA-like - - - ko:K02058 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp k141_11123_7 1232683.ADIMK_3961 3.35e-94 282.0 COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,465JK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Branched-chain amino acid transport system / permease component IV02_22045 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_15995_2 1177154.Y5S_01713 6.68e-16 82.8 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,1XI5R@135619|Oceanospirillales 135619|Oceanospirillales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16 k141_1370_1 1278309.KB907109_gene3295 2.47e-19 85.1 COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,1S2RI@1236|Gammaproteobacteria,1XJPS@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_1370_2 1278309.KB907109_gene3294 2e-78 234.0 COG0824@1|root,COG0824@2|Bacteria,1QSRH@1224|Proteobacteria,1RW9P@1236|Gammaproteobacteria,1XK26@135619|Oceanospirillales 135619|Oceanospirillales S thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 k141_1370_3 1278309.KB907109_gene3293 1.76e-121 348.0 COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,1S3VA@1236|Gammaproteobacteria,1XKCD@135619|Oceanospirillales 135619|Oceanospirillales P Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) phnN - 2.7.4.23 ko:K05774 ko00030,map00030 - R06836 RC00002 ko00000,ko00001,ko01000 - - - AAA_33 k141_7585_1 1288826.MSNKSG1_03655 7.57e-126 359.0 COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria,4688X@72275|Alteromonadaceae 1236|Gammaproteobacteria C Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 k141_7585_2 1288826.MSNKSG1_03650 5.25e-155 435.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,464M1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Carboxylesterase estB - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_7585_3 1288826.MSNKSG1_03645 6.44e-157 439.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,464SC@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B k141_7585_4 1288826.MSNKSG1_03640 0.0 913.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,469FM@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_7585_5 1288826.MSNKSG1_03635 3.61e-76 233.0 2FB4I@1|root,343AY@2|Bacteria,1P0MU@1224|Proteobacteria,1SS4Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12538_1 351348.Maqu_2192 0.0 1209.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria,4657T@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor fhuE - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k141_12538_3 225937.HP15_836 1.63e-102 306.0 COG4114@1|root,COG4114@2|Bacteria,1NMDK@1224|Proteobacteria,1SJB3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ferric iron reductase - - - - - - - - - - - - FhuF_C k141_12538_4 1415754.JQMK01000002_gene2967 0.0 958.0 COG0609@1|root,COG0609@2|Bacteria,1MVA3@1224|Proteobacteria,1RN0J@1236|Gammaproteobacteria,46ADQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuB - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_18765_1 204669.Acid345_1575 0.000846 44.3 COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia 204432|Acidobacteriia NU PFAM Type II secretion system F domain - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_2696_1 1288826.MSNKSG1_04941 1.76e-104 310.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,464VM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_2696_2 1288826.MSNKSG1_04936 6.91e-279 764.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,466JS@72275|Alteromonadaceae 1236|Gammaproteobacteria N Belongs to the bacterial flagellin family flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_2696_3 1288826.MSNKSG1_04931 0.0 1122.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,464V6@72275|Alteromonadaceae 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_8363_1 1499686.BN1079_01989 5.2e-52 186.0 COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,1RZUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T GGDEF Domain yliF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - iSBO_1134.SBO_0726 GAPES2,GGDEF k141_22239_1 697282.Mettu_3372 6.26e-82 248.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1S0SJ@1236|Gammaproteobacteria,1XET6@135618|Methylococcales 135618|Methylococcales H Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_N_3 k141_22239_2 1249627.D779_1704 4.27e-12 68.2 2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,1RZVK@1236|Gammaproteobacteria,1WWI9@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_21566_1 1265313.HRUBRA_02739 3.34e-98 292.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1J8FZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O prohibitin homologues - - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_21566_2 1265313.HRUBRA_02738 2.35e-127 372.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RPUE@1236|Gammaproteobacteria,1J825@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_7586_1 1005995.GTPT_0413 3.34e-07 57.4 COG3266@1|root,COG3266@2|Bacteria,1Q1YI@1224|Proteobacteria,1RRJF@1236|Gammaproteobacteria,4BU76@82986|Tatumella 1236|Gammaproteobacteria D Sporulation related domain damX GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - ko:K03112 - - - - ko00000 - - - AAA_22,SPOR k141_9633_1 1291050.JAGE01000001_gene3068 3.02e-97 322.0 COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,24YJI@186801|Clostridia 186801|Clostridia Q Beta-ketoacyl synthase - - - - - - - - - - - - Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt k141_15996_2 472759.Nhal_2635 1.01e-83 255.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales 135613|Chromatiales S subfamily IA, variant 1 - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_16636_1 1278309.KB907099_gene2624 1.38e-91 270.0 COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,1XMRX@135619|Oceanospirillales 135619|Oceanospirillales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_16636_2 243924.LT42_16465 1.94e-13 66.6 COG1977@1|root,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12 ko:K03636,ko:K03752,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395,R11581 RC02507 ko00000,ko00001,ko01000 - - iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775 ThiS k141_16636_3 1278309.KB907100_gene1775 1.07e-79 243.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1XJYU@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the CinA family - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_16636_5 1278309.KB907100_gene1773 1.44e-63 198.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1XM17@135619|Oceanospirillales 135619|Oceanospirillales S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX k141_16636_6 1278309.KB907100_gene1772 0.0 1502.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1XIHS@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k141_16636_7 1278309.KB907100_gene1771 9.01e-276 756.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XHQ7@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 k141_13912_1 1288826.MSNKSG1_14127 2.96e-87 263.0 COG1732@1|root,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RN72@1236|Gammaproteobacteria,46AFM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) yehZ GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iE2348C_1286.E2348C_2278,iEC55989_1330.EC55989_2381,iECIAI39_1322.ECIAI39_0865,iECO103_1326.ECO103_2607,iECSE_1348.ECSE_2399 OpuAC k141_13912_2 1288826.MSNKSG1_14122 2.26e-226 629.0 COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,1RQDV@1236|Gammaproteobacteria,46AQF@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1174 ABC-type proline glycine betaine transport systems, permease component yehY GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iECNA114_1301.ECNA114_2219,iECSF_1327.ECSF_2012,iETEC_1333.ETEC_2266 BPD_transp_1 k141_12539_2 1215092.PA6_007_00180 1.14e-06 50.8 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YD64@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_20803_1 76869.PputGB1_2811 7.5e-72 235.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1S12D@1236|Gammaproteobacteria,1YZIU@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_20803_2 930166.CD58_17565 4.28e-57 197.0 COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - PSII_BNR k141_20803_3 1278309.KB907099_gene2564 4.17e-175 513.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_3452_1 1288826.MSNKSG1_06688 3.27e-221 620.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II fadD1 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - iJN746.PP_4550 AMP-binding,AMP-binding_C k141_3452_2 1288826.MSNKSG1_06693 7.43e-105 303.0 COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,1S5Y3@1236|Gammaproteobacteria,468KB@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG2030 Acyl dehydratase phaJ - - - - - - - - - - - MaoC_dehydratas k141_3452_3 1288826.MSNKSG1_06698 1.85e-169 481.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C k141_3452_4 1288826.MSNKSG1_06703 2.19e-104 302.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,4681G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_3452_5 1288826.MSNKSG1_06708 2.21e-113 326.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_3452_6 1288826.MSNKSG1_06713 4.91e-132 377.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins aglR - - - - - - - - - - - MotA_ExbB k141_3452_8 1288826.MSNKSG1_06723 3.5e-105 304.0 COG0457@1|root,COG0457@2|Bacteria,1NP3J@1224|Proteobacteria,1SI3S@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_11,TPR_7 k141_3452_9 1288826.MSNKSG1_06728 4.9e-312 873.0 COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,YfiO k141_628_1 1278309.KB907101_gene574 1.73e-101 305.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XIWX@135619|Oceanospirillales 135619|Oceanospirillales K membrane rbn-1 - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_628_2 1278309.KB907101_gene573 5.27e-60 186.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1XKIG@135619|Oceanospirillales 135619|Oceanospirillales P arsenate reductase arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_628_3 1042375.AFPL01000023_gene1705 7.48e-47 155.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,466IM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red k141_6178_1 1278309.KB907107_gene1685 6.17e-55 195.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XKA8@135619|Oceanospirillales 135619|Oceanospirillales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_13228_1 631362.Thi970DRAFT_01664 3.56e-116 340.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1WW81@135613|Chromatiales 135613|Chromatiales E TIGRFAM Serine O-acetyltransferase - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N k141_6796_1 1123279.ATUS01000001_gene1426 5.04e-39 146.0 COG4872@1|root,COG4872@2|Bacteria,1NAIX@1224|Proteobacteria,1S1XV@1236|Gammaproteobacteria,1J9Q3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 k141_14505_1 367336.OM2255_07070 6.7e-73 229.0 COG1530@1|root,COG1530@2|Bacteria,1MWBR@1224|Proteobacteria,2TU44@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG1530 Ribonucleases G and E rng - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G k141_1372_2 626887.J057_12426 4.99e-14 70.9 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,4641J@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG3118 Thioredoxin domain-containing protein ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_8948_1 395961.Cyan7425_3617 1.95e-107 316.0 COG0637@1|root,COG0637@2|Bacteria,1G2T2@1117|Cyanobacteria,3KH3D@43988|Cyanothece 1117|Cyanobacteria S HAD-superfamily hydrolase, subfamily IA, variant 3 - - - - - - - - - - - - HAD_2 k141_11735_1 1247024.JRLH01000016_gene1680 3.12e-20 84.7 2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11735_2 1323663.AROI01000066_gene4026 1.25e-32 113.0 2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,1SDU5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16637_1 1121904.ARBP01000004_gene1024 3.1e-40 150.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47JRC@768503|Cytophagia 976|Bacteroidetes S PFAM peptidase S45 penicillin amidase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase k141_21567_1 1492922.GY26_18025 2.11e-64 211.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1J4WJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_11124_1 314278.NB231_15223 1.06e-145 443.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_11124_2 314278.NB231_15218 4.05e-38 135.0 2E08B@1|root,32VW1@2|Bacteria,1N4XX@1224|Proteobacteria,1S67B@1236|Gammaproteobacteria,1X0TY@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_4842_1 870187.Thini_1183 2.2e-159 456.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales 72273|Thiotrichales G RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site cbbL - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_20043_2 519989.ECTPHS_12585 2.76e-152 432.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1WW65@135613|Chromatiales 135613|Chromatiales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG k141_20043_3 1122603.ATVI01000006_gene598 9.53e-49 169.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1RZ95@1236|Gammaproteobacteria,1X3T7@135614|Xanthomonadales 135614|Xanthomonadales P transport protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k141_17353_1 187272.Mlg_1865 6.82e-152 460.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_17353_2 396588.Tgr7_1155 5.1e-42 140.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1WYT7@135613|Chromatiales 135613|Chromatiales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_13937_1 314278.NB231_12259 1.85e-123 384.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_13312_1 1278309.KB907099_gene2833 3.17e-154 443.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1XHDG@135619|Oceanospirillales 135619|Oceanospirillales T ATPase related to phosphate starvation-inducible protein PhoH phoH1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_13312_2 1278309.KB907099_gene2831 5.09e-07 50.4 COG0591@1|root,COG1842@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,1QX2W@1224|Proteobacteria,1RZNE@1236|Gammaproteobacteria,1XJ1J@135619|Oceanospirillales 135619|Oceanospirillales EKT Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - - k141_21008_1 195253.Syn6312_1034 2.27e-21 86.3 2EKBF@1|root,33E1U@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_16083_1 1185766.DL1_17745 2.19e-76 234.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2XMNM@285107|Thioclava 28211|Alphaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_16083_2 1208323.B30_02680 4.26e-07 50.4 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_5654_2 1397527.Q670_06565 1.98e-226 648.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XHWN@135619|Oceanospirillales 135619|Oceanospirillales J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_11911_1 1121352.JHZP01000001_gene865 5.8e-05 42.7 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,2KRA2@206351|Neisseriales 206351|Neisseriales S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_11911_3 883126.HMPREF9710_02179 1.06e-20 90.1 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,472UZ@75682|Oxalobacteraceae 28216|Betaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_11246_2 1123400.KB904791_gene107 3.61e-48 160.0 COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria 1224|Proteobacteria L PFAM NUDIX hydrolase - - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N_2 k141_11246_3 1121935.AQXX01000104_gene373 1.61e-26 98.2 2EA6R@1|root,30KMZ@2|Bacteria,1Q1AX@1224|Proteobacteria,1T8WJ@1236|Gammaproteobacteria,1XMUG@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3185) - - - - - - - - - - - - DUF3185 k141_2838_1 497321.C664_19361 1.21e-22 107.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,2WGY2@28216|Betaproteobacteria,2KVIH@206389|Rhodocyclales 206389|Rhodocyclales T COG2199 FOG GGDEF domain - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_751_1 1121004.ATVC01000013_gene2079 2.9e-71 243.0 COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1RH0R@1224|Proteobacteria,2VRQD@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM ATP-binding region, ATPase domain protein - - - - - - - - - - - - HATPase_c k141_8416_1 1033802.SSPSH_002045 1.02e-27 111.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Mg2 and Co2 transporter CorB yfjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_8416_2 105559.Nwat_2094 2.2e-29 112.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales 135613|Chromatiales S Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_2144_1 1097668.BYI23_A015180 9.38e-85 265.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,1K3BG@119060|Burkholderiaceae 28216|Betaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_3539_1 1288826.MSNKSG1_07818 0.0 1668.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,46445@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_3539_2 1288826.MSNKSG1_07813 5.27e-137 388.0 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,466MT@72275|Alteromonadaceae 1236|Gammaproteobacteria FJ COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE k141_3539_3 1288826.MSNKSG1_07808 1.65e-207 574.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,465VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator finR - - - - - - - - - - - HTH_1,LysR_substrate k141_3539_4 1288826.MSNKSG1_07803 2.41e-186 517.0 COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria,1T1MX@1236|Gammaproteobacteria,46574@72275|Alteromonadaceae 1236|Gammaproteobacteria CH COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 fpr - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_3539_5 1288826.MSNKSG1_07798 9.4e-295 805.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RU5Z@1236|Gammaproteobacteria,46ARX@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - Sugar_tr k141_3539_6 1288826.MSNKSG1_07793 6.06e-190 529.0 COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,466D1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ion transport protein kch - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans k141_11912_1 998088.B565_2775 5.82e-48 170.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1Y5DQ@135624|Aeromonadales 135624|Aeromonadales GM CoA-binding domain - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_52_1 765912.Thimo_2579 1.85e-194 555.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales 135613|Chromatiales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k141_5655_1 1121878.AUGL01000008_gene1380 5.35e-35 126.0 COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,1T24M@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_5655_2 1231391.AMZF01000110_gene897 4.77e-43 148.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,3T3RD@506|Alcaligenaceae 28216|Betaproteobacteria S Phospholipase/Carboxylesterase estB - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_16787_1 1144672.F966_02017 2.3e-53 189.0 COG0388@1|root,COG0388@2|Bacteria,1MX9Z@1224|Proteobacteria,1RR89@1236|Gammaproteobacteria,3NQDG@468|Moraxellaceae 1236|Gammaproteobacteria S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - - - - - - - - - - RVT_1 k141_20285_1 870187.Thini_4021 4.93e-55 176.0 2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,1S5CH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nitrogen fixation protein - - - - - - - - - - - - DUF269 k141_20285_2 395493.BegalDRAFT_0791 1.89e-49 163.0 COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,1S50W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Dinitrogenase iron-molybdenum cofactor nifX - - ko:K02596 - - - - ko00000 - - - Nitro_FeMo-Co k141_752_1 246200.SPO1021 9.62e-100 301.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria,4NBNG@97050|Ruegeria 28211|Alphaproteobacteria E branched-chain amino acid - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6,TAT_signal k141_10519_1 28229.ND2E_0402 2.64e-59 207.0 COG5635@1|root,COG5635@2|Bacteria,1MY1P@1224|Proteobacteria,1RZKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Nacht domain - - - - - - - - - - - - - k141_13314_1 367336.OM2255_09576 1.89e-114 363.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_14001_1 644282.Deba_2226 8e-64 220.0 COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria 28221|Deltaproteobacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Pyr_redox_2 k141_1451_1 1118153.MOY_14960 6.01e-54 181.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,1RP1B@1236|Gammaproteobacteria,1XIRN@135619|Oceanospirillales 135619|Oceanospirillales C COG2864 Cytochrome b subunit of formate dehydrogenase - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB k141_1451_2 243159.AFE_2126 5.22e-10 60.1 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,2NBTG@225057|Acidithiobacillales 225057|Acidithiobacillales I glycerol-3-phosphate metabolic process gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_9809_1 391615.ABSJ01000034_gene1068 1.74e-31 119.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S602@1236|Gammaproteobacteria 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_9809_2 1249627.D779_2639 1.48e-48 158.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator receiver - - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_9809_3 40215.BBOS01000065_gene1428 2.94e-07 55.8 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1SATV@1236|Gammaproteobacteria,3NJ7K@468|Moraxellaceae 1236|Gammaproteobacteria NT Two component signalling adaptor domain pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_8417_1 1049564.TevJSym_bi00190 2.39e-76 246.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_4221_1 156889.Mmc1_2137 3.76e-197 558.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component dctM GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM,DctQ k141_4221_2 1123401.JHYQ01000001_gene1796 2.05e-54 177.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_18176_1 1288826.MSNKSG1_10043 6.22e-181 523.0 COG1704@1|root,COG1704@2|Bacteria,1NS0H@1224|Proteobacteria,1SKFZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S E3 Ubiquitin ligase - - - - - - - - - - - - GIDE,LemA k141_18176_2 1288826.MSNKSG1_10038 7.17e-188 522.0 COG2267@1|root,COG2267@2|Bacteria,1QW7I@1224|Proteobacteria,1T51N@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Ndr family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_18176_3 1288826.MSNKSG1_10033 2.76e-188 525.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1SYGG@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the reduction of tatronate semialdehyde to D- glycerate - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_18176_4 1318628.MARLIPOL_02570 4.98e-134 381.0 COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,1S992@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 k141_19587_1 1288826.MSNKSG1_09888 1.71e-76 235.0 COG0596@1|root,COG0657@1|root,COG0596@2|Bacteria,COG0657@2|Bacteria,1RGAP@1224|Proteobacteria,1S1M7@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_19587_2 1288826.MSNKSG1_09893 1.2e-61 189.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,468BE@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - ko:K07401 - - - - ko00000 - - - Rdx k141_19587_3 1288826.MSNKSG1_09898 2.03e-220 607.0 COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,1RP4M@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha beta hydrolase - - 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_19587_4 1288826.MSNKSG1_09903 3.09e-171 479.0 COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,466HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P ZIP Zinc transporter zupT GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - iECIAI39_1322.ECIAI39_3536 Zip k141_19587_5 1288826.MSNKSG1_09908 1.34e-202 562.0 COG0583@1|root,COG0583@2|Bacteria,1MV0E@1224|Proteobacteria,1S2C3@1236|Gammaproteobacteria,46CDC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_19587_6 1288826.MSNKSG1_09913 0.0 985.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,465SP@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_19587_7 1288826.MSNKSG1_09918 3.19e-298 819.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_18195_1 1288826.MSNKSG1_09293 3.6e-241 668.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_18195_2 1288826.MSNKSG1_09298 1.31e-111 321.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,467AG@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase or kinase yjeE GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE k141_18195_3 1288826.MSNKSG1_09303 0.0 901.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_18195_4 1288826.MSNKSG1_09308 1.5e-265 727.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,46459@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_18195_5 1288826.MSNKSG1_09313 5.1e-122 350.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,466JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k141_18195_6 1288826.MSNKSG1_09318 3.63e-247 679.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,464F3@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675 RsgA_GTPase k141_18195_7 1288826.MSNKSG1_09323 3.08e-217 601.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar Motor Protein motB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_11265_1 90813.JQMT01000001_gene985 7.55e-71 225.0 COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria 1224|Proteobacteria P C4-dicarboxylate transporter malic acid transport protein tdt - - ko:K03304 - - - - ko00000,ko02000 2.A.16.1 - - SLAC1 k141_7759_1 1026882.MAMP_00009 6.87e-19 89.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,460ZY@72273|Thiotrichales 72273|Thiotrichales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_7759_2 472759.Nhal_0184 1.18e-14 70.9 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales 135613|Chromatiales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_3561_1 1249627.D779_2147 3.58e-31 112.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,1WYI4@135613|Chromatiales 135613|Chromatiales P sulfur relay protein TusB DsrH - - - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_3561_2 1266909.AUAG01000010_gene2615 1.55e-50 161.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1WYFA@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_20308_1 203122.Sde_1987 6.65e-30 116.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_10532_1 472759.Nhal_1115 4.61e-81 265.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_19588_1 717774.Marme_3975 1.76e-61 198.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XHUE@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10553 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - BPD_transp_2 k141_19588_2 391038.Bphy_3594 5.41e-23 94.4 COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2VID6@28216|Betaproteobacteria,1K5HJ@119060|Burkholderiaceae 28216|Betaproteobacteria G PFAM ABC transporter related rbsA - - ko:K10554 ko02010,map02010 M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.7 - - ABC_tran k141_14733_1 1236494.BAJN01000001_gene238 1.81e-11 71.2 COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia 976|Bacteroidetes S Von Willebrand factor type A domain batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 k141_2855_2 89187.ISM_14805 1.36e-133 394.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,46NP9@74030|Roseovarius 28211|Alphaproteobacteria H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_7760_2 339671.Asuc_0293 6.82e-20 87.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1Y7XF@135625|Pasteurellales 135625|Pasteurellales S Competence protein F comF - - - - - - - - - - - Pribosyltran k141_768_1 1049564.TevJSym_ax00030 2.03e-59 200.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1J4K9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_11266_1 1286106.MPL1_11553 7.28e-86 267.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,45ZX9@72273|Thiotrichales 72273|Thiotrichales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_6336_1 391615.ABSJ01000037_gene945 6.52e-46 166.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1J55U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Multicopper oxidase pcoA - - - - - - - - - - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_1464_1 1423144.Gal_01447 2.43e-25 111.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,34DTQ@302485|Phaeobacter 28211|Alphaproteobacteria M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C k141_18196_1 1122185.N792_11200 4.67e-41 144.0 COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,1S4JR@1236|Gammaproteobacteria,1X5AP@135614|Xanthomonadales 135614|Xanthomonadales IQ Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2 k141_18196_2 1163408.UU9_14455 3.79e-57 189.0 COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria,1X36X@135614|Xanthomonadales 135614|Xanthomonadales IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_21657_1 1049564.TevJSym_aj00080 6.3e-44 152.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1JADW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl k141_3562_1 999141.GME_04272 3.11e-53 170.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1XJ9H@135619|Oceanospirillales 135619|Oceanospirillales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK k141_3562_2 686340.Metal_1936 2.04e-59 195.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1XE4Q@135618|Methylococcales 135618|Methylococcales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_15432_1 580332.Slit_1327 5.42e-28 115.0 COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales 28216|Betaproteobacteria T SMART ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_4 k141_15432_2 697282.Mettu_3285 7.11e-32 113.0 COG0724@1|root,COG0724@2|Bacteria,1NDEM@1224|Proteobacteria,1SFDX@1236|Gammaproteobacteria,1XFGC@135618|Methylococcales 135618|Methylococcales S PFAM RNA recognition motif - - - - - - - - - - - - RRM_1 k141_15432_3 550540.Fbal_1627 1.15e-30 108.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_17471_1 1288826.MSNKSG1_13017 9.47e-285 810.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,464U2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_17471_2 1288826.MSNKSG1_13022 9.05e-274 750.0 COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,1RQ2B@1236|Gammaproteobacteria,469XP@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_17471_3 1288826.MSNKSG1_13027 1.96e-181 506.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RYZH@1236|Gammaproteobacteria,469EE@72275|Alteromonadaceae 1236|Gammaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_17471_4 1288826.MSNKSG1_13032 7.69e-225 620.0 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,1RNDQ@1236|Gammaproteobacteria,465JG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Mediates influx of magnesium ions corA GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYL1228.KPN_04313 CorA k141_17471_5 1288826.MSNKSG1_13037 0.0 1429.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4655N@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_1632_2 572477.Alvin_2887 7.18e-32 122.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales 135613|Chromatiales S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_16954_1 519989.ECTPHS_08116 1.31e-53 184.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales 135613|Chromatiales G PFAM glycoside hydrolase, family 77 - - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_16233_1 1278309.KB907099_gene3043 2.5e-115 338.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1XHPN@135619|Oceanospirillales 135619|Oceanospirillales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_13483_1 4006.Lus10000390 2.78e-25 107.0 COG0069@1|root,KOG0399@2759|Eukaryota,37RTT@33090|Viridiplantae,3G7BE@35493|Streptophyta,4JK1V@91835|fabids 35493|Streptophyta E glutamate synthase GLT1 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009719,GO:0009725,GO:0009735,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015930,GO:0016040,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0032502,GO:0040007,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045181,GO:0046394,GO:0046686,GO:0048589,GO:0050896,GO:0055114,GO:0060359,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698 1.4.1.13,1.4.1.14 ko:K00264 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,GATase_2,GXGXG,Glu_syn_central,Glu_synthase,Pyr_redox_2 k141_5098_1 1249627.D779_4118 2.75e-67 222.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_3029_1 635013.TherJR_2223 2.76e-145 455.0 COG1470@1|root,COG5276@1|root,COG1470@2|Bacteria,COG5276@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - ko:K12287 - - - - ko00000,ko02044 - - - Big_5,CarboxypepD_reg,DUF1566,He_PIG,LVIVD,SLH k141_3029_2 1033802.SSPSH_000255 1.81e-20 93.2 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M outer membrane protein W ompW GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K07275 - - - - ko00000 - - - OmpW k141_15586_1 1033732.CAHI01000004_gene2017 2.27e-09 61.2 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FMVV@200643|Bacteroidia 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y k141_15586_2 247633.GP2143_16311 1.53e-94 291.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1J4H6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX k141_12795_1 1278309.KB907100_gene2126 2.38e-118 357.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XHTD@135619|Oceanospirillales 135619|Oceanospirillales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_9254_1 95619.PM1_0204690 2.96e-58 202.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_17665_1 314285.KT71_003831 2.36e-57 198.0 2C99D@1|root,31TYV@2|Bacteria,1QRSH@1224|Proteobacteria,1SPD5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA-sulfur modification-associated - - - - - - - - - - - - - k141_9937_2 519989.ECTPHS_12798 7.28e-70 215.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WVXA@135613|Chromatiales 135613|Chromatiales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_9937_3 1049564.TevJSym_au00100 3.51e-123 359.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1J5DH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Bacterial transferase hexapeptide (six repeats) cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0840 Hexapep,SATase_N k141_9937_4 95619.PM1_0215965 2.34e-93 282.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_9937_5 519989.ECTPHS_12783 4.09e-118 345.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales 135613|Chromatiales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_9937_7 1049564.TevJSym_an00600 2.47e-128 375.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1J543@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_9937_8 1249627.D779_0228 4.52e-104 321.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_18364_1 1278309.KB907107_gene1735 8.84e-188 528.0 COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XRTE@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8 k141_5099_1 1249627.D779_3509 1.23e-45 164.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1X2PK@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c k141_4438_1 391615.ABSJ01000042_gene2194 4.3e-28 123.0 COG4254@1|root,COG4254@2|Bacteria,1RJR0@1224|Proteobacteria,1S8WR@1236|Gammaproteobacteria,1JBNT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S FecR protein - - - - - - - - - - - - FecR k141_10714_2 713586.KB900536_gene1196 1.06e-49 171.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1WXXP@135613|Chromatiales 135613|Chromatiales O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k141_12098_1 882378.RBRH_03928 1.24e-24 98.6 COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,1K0S5@119060|Burkholderiaceae 28216|Betaproteobacteria S UPF0114 protein - - - - - - - - - - - - UPF0114 k141_12098_2 1123393.KB891316_gene2033 9.18e-114 339.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KRAF@119069|Hydrogenophilales 119069|Hydrogenophilales F ATP-grasp domain - - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp k141_15587_2 1479237.JMLY01000001_gene1338 2.02e-35 126.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,465S7@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_18365_1 1123237.Salmuc_03567 1.63e-71 228.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_7927_1 1485545.JQLW01000005_gene1063 6.94e-41 145.0 COG2227@1|root,COG2227@2|Bacteria,1QY24@1224|Proteobacteria 1224|Proteobacteria H Pfam Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_14892_1 105559.Nwat_2213 1.44e-85 272.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1WWGJ@135613|Chromatiales 135613|Chromatiales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_9938_1 292414.TM1040_0150 1.63e-90 273.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,4NAW6@97050|Ruegeria 28211|Alphaproteobacteria H Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_9255_2 768671.ThimaDRAFT_1211 3e-77 259.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k141_8604_1 1116472.MGMO_87c00020 1.5e-16 78.6 COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,1XEIB@135618|Methylococcales 135618|Methylococcales S TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP k141_8604_2 572477.Alvin_0250 4.08e-49 167.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1WXVN@135613|Chromatiales 135613|Chromatiales G PfkB domain protein - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_3032_1 1415756.JQMY01000001_gene2648 1.06e-117 356.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2PDC6@252301|Oceanicola 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_4439_1 404589.Anae109_0028 1.3e-36 132.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales 28221|Deltaproteobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_4439_2 1485544.JQKP01000011_gene740 3.58e-14 71.2 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria,44V5J@713636|Nitrosomonadales 28216|Betaproteobacteria G Belongs to the glucose-6-phosphate 1-epimerase family - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_17666_1 1042375.AFPL01000044_gene1251 2.34e-41 155.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_17666_2 1278309.KB907100_gene2097 1.11e-25 100.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XJD4@135619|Oceanospirillales 135619|Oceanospirillales P COG1392 Phosphate transport regulator (distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_7196_1 1278309.KB907102_gene109 3.16e-36 122.0 2EUU1@1|root,33N9J@2|Bacteria,1NJG7@1224|Proteobacteria,1SGFA@1236|Gammaproteobacteria,1XQM4@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7196_2 1278309.KB907102_gene108 1.78e-164 466.0 COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,1XI2D@135619|Oceanospirillales 135619|Oceanospirillales P Peroxidase - - - ko:K07223 - - - - ko00000 - - - Dyp_perox k141_7196_3 1278309.KB907102_gene107 7.22e-79 235.0 COG2315@1|root,COG2315@2|Bacteria,1N12P@1224|Proteobacteria,1S8W4@1236|Gammaproteobacteria,1XKE8@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - YjbR k141_7196_4 1123400.KB904748_gene314 2.7e-50 169.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria P sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_21848_1 1278309.KB907107_gene1662 1.72e-64 197.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_21848_3 1278309.KB907107_gene1664 7.36e-80 242.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1XKBD@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf k141_5100_1 661367.LLO_0185 8.09e-19 84.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1JC9C@118969|Legionellales 118969|Legionellales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_5100_2 768671.ThimaDRAFT_2966 1.94e-75 246.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_16234_2 153948.NAL212_1204 3.78e-111 335.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,372RT@32003|Nitrosomonadales 28216|Betaproteobacteria O PFAM Magnesium chelatase, ChlI subunit comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_18366_1 1452718.JBOY01000083_gene2778 3.86e-10 60.8 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases dnr - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_18366_2 1122599.AUGR01000017_gene2978 7.45e-67 205.0 COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria,1XKAN@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c - - - ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 - - Cytochrom_C k141_14181_1 207954.MED92_02201 5.11e-180 506.0 COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,1RNJM@1236|Gammaproteobacteria,1XIZG@135619|Oceanospirillales 135619|Oceanospirillales K AraC-like ligand binding domain - - - ko:K02508 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 k141_14181_2 1278309.KB907103_gene1147 2.72e-173 489.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1RSQV@1236|Gammaproteobacteria,1XJJG@135619|Oceanospirillales 135619|Oceanospirillales K PFAM flavin reductase domain protein FMN-binding - - - - - - - - - - - - Flavin_Reduct k141_14181_3 1278309.KB907103_gene1146 1.17e-30 110.0 COG4859@1|root,COG4859@2|Bacteria,1RJ97@1224|Proteobacteria,1S7PB@1236|Gammaproteobacteria,1XK60@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2185) - - - - - - - - - - - - DUF2185 k141_19089_1 1528106.JRJE01000032_gene2602 6.65e-19 90.1 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2JRMZ@204441|Rhodospirillales 204441|Rhodospirillales S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC k141_19089_2 396588.Tgr7_1529 2.37e-84 257.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1WXXM@135613|Chromatiales 135613|Chromatiales S HAD-superfamily hydrolase, subfamily IA, variant 1 - - 3.1.3.105 ko:K22292 ko00520,map00520 - R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_19089_3 491952.Mar181_1209 1.18e-97 290.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XH4S@135619|Oceanospirillales 135619|Oceanospirillales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 k141_9939_1 667632.KB890217_gene4893 9.68e-29 112.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,1JZMZ@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM FAD linked oxidase glcE - 1.1.3.15 ko:K00104,ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_9939_2 1182590.BN5_00125 1.11e-48 168.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1YFBX@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C 4Fe-4S dicluster domain glcF GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - iECABU_c1320.ECABU_c33760,iECIAI1_1343.ECIAI1_3119,iECIAI39_1322.ECIAI39_3465,iECNA114_1301.ECNA114_3053,iECP_1309.ECP_3055,iJN746.PP_3747 CCG,Fer4_7,Fer4_8 k141_19730_1 713586.KB900536_gene2264 1.76e-99 299.0 COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_19730_2 713586.KB900536_gene2263 3.12e-55 177.0 COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_2279_1 96561.Dole_0612 2.55e-41 176.0 COG2911@1|root,COG2931@1|root,COG3210@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria,2MNAP@213118|Desulfobacterales 28221|Deltaproteobacteria Q Hemolysin-type calcium-binding - - - - - - - - - - - - FecR,HemolysinCabind,VWA_2 k141_2279_2 90814.KL370891_gene747 8e-40 134.0 2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3467) - - - - - - - - - - - - DUF3467 k141_2279_3 1479235.KK366039_gene156 6.17e-34 142.0 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,1RXZP@1236|Gammaproteobacteria,1XIRF@135619|Oceanospirillales 135619|Oceanospirillales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23 k141_7197_1 998088.B565_3278 1.02e-13 76.6 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_1635_1 1123392.AQWL01000002_gene1882 6.43e-12 64.7 2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_16959_1 349124.Hhal_0566 5.63e-23 96.3 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,1WW2D@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH k141_7929_1 314278.NB231_11614 4.91e-60 208.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 k141_4441_1 1500893.JQNB01000001_gene1242 5.19e-69 218.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1XC7M@135614|Xanthomonadales 135614|Xanthomonadales GM NmrA-like family - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - NAD_binding_10 k141_10715_1 519989.ECTPHS_10346 7.86e-89 267.0 COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,1S2B6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_10715_2 768671.ThimaDRAFT_3698 8.73e-43 155.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_12100_1 292415.Tbd_0601 1.38e-154 443.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,2VN1T@28216|Betaproteobacteria,1KSVG@119069|Hydrogenophilales 119069|Hydrogenophilales C Domain of unknown function (DUF4931) - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - - k141_3034_1 1278309.KB907099_gene2860 1.21e-135 398.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XHH7@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_17667_1 999611.KI421504_gene3496 1.25e-89 268.0 COG1802@1|root,COG1802@2|Bacteria,1RAW8@1224|Proteobacteria,2U5UI@28211|Alphaproteobacteria 28211|Alphaproteobacteria K GntR family - - - - - - - - - - - - FCD,GntR k141_20484_1 1288826.MSNKSG1_09508 1.14e-309 844.0 COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,1RQYS@1236|Gammaproteobacteria,467UY@72275|Alteromonadaceae 1236|Gammaproteobacteria S unusual protein kinase - - - - - - - - - - - - ABC1 k141_20484_2 1288826.MSNKSG1_09503 2.54e-102 299.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria,466CE@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) ycgM - - - - - - - - - - - FAA_hydrolase k141_14894_1 637389.Acaty_c0451 1.32e-41 149.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1RPST@1236|Gammaproteobacteria,2NCBD@225057|Acidithiobacillales 225057|Acidithiobacillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_19090_1 398580.Dshi_2373 7.78e-108 326.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_2280_1 768670.Calni_1836 3.13e-52 185.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2GF7H@200930|Deferribacteres 200930|Deferribacteres T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_9257_1 1460634.JCM19037_987 8.06e-05 48.1 COG0730@1|root,COG0730@2|Bacteria,1V4FT@1239|Firmicutes,4HHYT@91061|Bacilli 91061|Bacilli S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_9271_1 1122137.AQXF01000002_gene652 2.06e-88 270.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TTHH@28211|Alphaproteobacteria 28211|Alphaproteobacteria K LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k141_4464_1 697282.Mettu_3851 9.68e-30 111.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,1XFCP@135618|Methylococcales 135618|Methylococcales N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach k141_233_1 1278309.KB907107_gene1642 1.67e-232 648.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBT@135619|Oceanospirillales 135619|Oceanospirillales E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_8615_1 1121405.dsmv_0392 1.17e-36 135.0 COG0394@1|root,COG0655@1|root,COG0394@2|Bacteria,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MIC1@213118|Desulfobacterales 28221|Deltaproteobacteria T PFAM NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red,LMWPc k141_21872_1 99598.Cal7507_4444 3.67e-35 135.0 COG0491@1|root,COG4529@1|root,COG0491@2|Bacteria,COG4529@2|Bacteria,1G0CZ@1117|Cyanobacteria,1HMAK@1161|Nostocales 1117|Cyanobacteria S Hydrolase - - - - - - - - - - - - Lactamase_B,NAD_binding_9 k141_8720_1 1288826.MSNKSG1_10828 0.0 1251.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,463Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria T PrkA family serine protein kinase yeaG GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_8720_2 1288826.MSNKSG1_10833 1.28e-230 641.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,464ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k141_7341_1 1121013.P873_03555 1.18e-37 145.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1X6QS@135614|Xanthomonadales 135614|Xanthomonadales C Cysteine-rich domain - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 k141_7341_2 228410.NE1874 3.9e-39 132.0 COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,373AC@32003|Nitrosomonadales 28216|Betaproteobacteria C Ferredoxin fdx - - - - - - - - - - - 2Fe-2S_thioredx k141_1790_2 396588.Tgr7_0746 1.55e-86 267.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WX7G@135613|Chromatiales 135613|Chromatiales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC2 - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_4572_1 1125973.JNLC01000011_gene614 3.28e-106 320.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2TQMC@28211|Alphaproteobacteria,3JWVJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S PrpF protein - - 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF k141_6602_1 1278309.KB907101_gene520 1.93e-152 443.0 28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria,1XJA1@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - DUF4129 k141_6602_2 1278309.KB907101_gene519 4.98e-09 56.2 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,1XJ7W@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - SpoIIM k141_1080_1 1049564.TevJSym_ar00510 3.8e-09 55.8 COG4106@1|root,COG4106@2|Bacteria,1QWJU@1224|Proteobacteria 1224|Proteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_1080_2 985255.APHJ01000025_gene1009 1.59e-58 199.0 COG1292@1|root,COG1292@2|Bacteria,4NEIW@976|Bacteroidetes,1HXKK@117743|Flavobacteriia,2P5H3@244698|Gillisia 976|Bacteroidetes M BCCT, betaine/carnitine/choline family transporter - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k141_17811_1 1288826.MSNKSG1_11693 1.46e-146 436.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,46433@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_17811_2 1288826.MSNKSG1_11688 4.12e-93 272.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,46857@72275|Alteromonadaceae 1236|Gammaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k141_17811_3 1288826.MSNKSG1_11683 2.09e-213 590.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,4646V@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N k141_17811_4 1288826.MSNKSG1_11678 1.44e-54 171.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,4682T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 k141_17811_5 1288826.MSNKSG1_11668 1.68e-218 619.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4651T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_3846_1 187272.Mlg_2496 5.64e-148 442.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales 135613|Chromatiales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_18477_1 713586.KB900536_gene1659 1.56e-78 239.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1WWM4@135613|Chromatiales 135613|Chromatiales H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 k141_18477_2 870187.Thini_2005 1.1e-99 296.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3412,iSDY_1059.SDY_0027 AdoMet_dc k141_13617_1 1298593.TOL_2357 1.19e-128 424.0 COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Response_reg,dCache_2,sCache_2 k141_13617_2 1278309.KB907101_gene411 6.01e-42 138.0 COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,1XMJZ@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - Transgly_assoc k141_386_1 395493.BegalDRAFT_1624 4.28e-189 533.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,45ZWM@72273|Thiotrichales 72273|Thiotrichales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metXS - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_386_2 1033802.SSPSH_002815 5.47e-73 225.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW k141_19872_1 1278309.KB907102_gene40 1.85e-62 192.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XJIQ@135619|Oceanospirillales 135619|Oceanospirillales J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_19872_2 1278309.KB907102_gene41 2.9e-80 239.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1XJHH@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 k141_19872_3 1122201.AUAZ01000032_gene1587 1.68e-121 348.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,465S7@72275|Alteromonadaceae 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_19872_4 1278309.KB907102_gene43 9.65e-289 790.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1XHEG@135619|Oceanospirillales 135619|Oceanospirillales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B k141_19872_5 1323663.AROI01000006_gene2985 1.06e-17 80.9 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_18478_1 1288826.MSNKSG1_06233 9.87e-118 346.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,464DX@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-binding protein - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_6603_1 1288826.MSNKSG1_06073 2.97e-85 257.0 COG1073@1|root,COG1073@2|Bacteria,1NX86@1224|Proteobacteria,1T2HF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 k141_17812_1 713586.KB900536_gene1766 2.76e-48 159.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k141_13618_1 393595.ABO_1091 4.33e-10 60.1 COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,1XIEA@135619|Oceanospirillales 135619|Oceanospirillales J COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans k141_8124_3 1249627.D779_1618 3.44e-70 222.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1WXWI@135613|Chromatiales 135613|Chromatiales H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_8124_4 261292.Nit79A3_2778 7.26e-106 317.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,371N7@32003|Nitrosomonadales 28216|Betaproteobacteria H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_8124_5 580332.Slit_2587 4.85e-49 168.0 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,44VRK@713636|Nitrosomonadales 28216|Betaproteobacteria I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_12967_1 1278309.KB907099_gene3123 3.79e-74 235.0 2C55T@1|root,2ZARV@2|Bacteria,1R77G@1224|Proteobacteria 1224|Proteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 k141_16381_1 1122194.AUHU01000014_gene1160 2.44e-22 102.0 COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,464YD@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1283 Na phosphate symporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans k141_20630_1 314345.SPV1_13177 7.78e-42 150.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel ynaI - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel k141_1805_1 292415.Tbd_0077 0.0 878.0 COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,1KS6X@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome D1 heme domain - - 1.7.2.1,1.7.99.1 ko:K15864 ko00910,ko01120,map00910,map01120 M00529 R00143,R00783,R00785 RC00086,RC02797 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_D1,Cytochrome_CBB3 k141_1805_2 713586.KB900536_gene2303 1.15e-95 285.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme - - - - - - - - - - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_10865_1 1288826.MSNKSG1_04501 0.0 1306.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_10865_2 1288826.MSNKSG1_04506 7.68e-265 726.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k141_10865_3 1288826.MSNKSG1_04511 0.0 989.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k141_10865_4 1288826.MSNKSG1_04516 6.32e-66 209.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,467E4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family fieF - - - - - - - - - - - Cation_efflux,ZT_dimer k141_6618_1 314270.RB2083_259 1.01e-26 106.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,3ZI0S@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N k141_6618_2 999547.KI421500_gene2187 2.22e-72 226.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,28097@191028|Leisingera 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain ycjG GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N k141_15745_1 379731.PST_1083 3.44e-85 265.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1YZT9@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_1103_1 870187.Thini_1279 6.54e-80 245.0 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k141_2468_2 1288826.MSNKSG1_01868 1.5e-96 303.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM k141_8733_1 1288826.MSNKSG1_18075 3.14e-82 273.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_10130_1 626887.J057_23820 2.37e-41 146.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,466TP@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0739 Membrane proteins related to metalloendopeptidases nlpD GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - ko:K06194,ko:K12943 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_402_1 1255043.TVNIR_3263 6.02e-119 352.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1WW9J@135613|Chromatiales 135613|Chromatiales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt k141_4590_1 1278309.KB907099_gene2489 4.34e-112 350.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XISY@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase - - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,Response_reg k141_10866_1 395493.BegalDRAFT_2970 7.43e-35 137.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales 72273|Thiotrichales T Methyl-accepting chemotaxis protein (MCP) signaling domain - - - - - - - - - - - - HAMP,MCPsignal k141_7354_1 1288826.MSNKSG1_18250 2.6e-118 353.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,464F2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_1806_1 1122180.Lokhon_00767 5.46e-96 290.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2P8J4@245186|Loktanella 28211|Alphaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_9397_1 1049564.TevJSym_an00380 3.54e-82 259.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C k141_19256_1 1288826.MSNKSG1_17436 2.75e-89 293.0 28S27@1|root,2ZEE0@2|Bacteria,1RAGA@1224|Proteobacteria,1S3DZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial Ig-like domain - - - - - - - - - - - - Big_5 k141_15009_1 1123368.AUIS01000001_gene1884 4.01e-50 169.0 COG0607@1|root,COG0607@2|Bacteria,1P2AX@1224|Proteobacteria,1SRQD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_16382_1 1278309.KB907099_gene2444 2.86e-98 291.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 k141_16382_2 1278309.KB907099_gene2445 4.51e-66 202.0 COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,1XK6I@135619|Oceanospirillales 135619|Oceanospirillales K Nitrogen regulatory protein P-II - - - - - - - - - - - - - k141_16382_3 1278309.KB907099_gene2446 1.17e-26 100.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XJZ5@135619|Oceanospirillales 135619|Oceanospirillales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_2469_1 1150600.ADIARSV_0278 1.51e-27 116.0 COG0521@1|root,COG0521@2|Bacteria,4NMFH@976|Bacteroidetes,1IS52@117747|Sphingobacteriia 976|Bacteroidetes H Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 k141_18495_1 396588.Tgr7_2996 9.61e-132 387.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_8127_1 105559.Nwat_0267 1.75e-45 159.0 COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,1S64C@1236|Gammaproteobacteria,1X05J@135613|Chromatiales 135613|Chromatiales S membrane-bound metal-dependent - - - ko:K07038 - - - - ko00000 - - - YdjM k141_1105_2 221103.XP_007846557.1 9.33e-07 53.9 COG1404@1|root,KOG3525@2759|Eukaryota,38C1N@33154|Opisthokonta,3NV4P@4751|Fungi,3UZBI@5204|Basidiomycota,2255B@155619|Agaricomycetes,3W668@5338|Agaricales 4751|Fungi O Kex protein KEX2 GO:0000139,GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0004857,GO:0004866,GO:0004867,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005794,GO:0005802,GO:0006508,GO:0006807,GO:0007323,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009892,GO:0009986,GO:0010466,GO:0010467,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016485,GO:0016540,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031324,GO:0031984,GO:0032268,GO:0032269,GO:0032588,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043900,GO:0043902,GO:0044092,GO:0044238,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045861,GO:0046999,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051604,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070011,GO:0071432,GO:0071704,GO:0080090,GO:0098588,GO:0098772,GO:0098791,GO:0140096,GO:1901564,GO:2000241,GO:2000243 3.4.21.61 ko:K01341 - - - - ko00000,ko01000,ko01002,ko03110 - - - P_proprotein,Peptidase_S8 k141_3207_1 1288826.MSNKSG1_07988 1.86e-126 365.0 COG0679@1|root,COG0679@2|Bacteria,1RA01@1224|Proteobacteria,1SZPD@1236|Gammaproteobacteria,467T3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_3207_2 1288826.MSNKSG1_07993 0.0 1944.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464FM@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_3207_3 1288826.MSNKSG1_07998 1.21e-19 85.1 COG0300@1|root,COG0300@2|Bacteria,1R9VQ@1224|Proteobacteria,1S1WG@1236|Gammaproteobacteria,46AYC@72275|Alteromonadaceae 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short k141_15747_1 1191523.MROS_0760 2.41e-142 417.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB k141_11545_1 1122599.AUGR01000005_gene1959 3.29e-96 291.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RSQU@1236|Gammaproteobacteria,1XIYG@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C k141_21328_1 1502724.FF80_02323 4.19e-58 194.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,3N64S@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_20631_2 523791.Kkor_1481 8.82e-33 121.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales 135619|Oceanospirillales S colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V k141_7355_1 467661.RKLH11_414 2.05e-44 154.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,3ZGC8@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_16383_1 714943.Mucpa_7010 6.05e-78 255.0 COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IP7J@117747|Sphingobacteriia 976|Bacteroidetes P SPTR ATPase, P-type (Transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_10131_1 270374.MELB17_14281 7.32e-78 264.0 COG3533@1|root,COG3533@2|Bacteria,1QXFU@1224|Proteobacteria,1T3AW@1236|Gammaproteobacteria,46D4B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Beta-L-arabinofuranosidase, GH127 - - - - - - - - - - - - - k141_12267_1 420662.Mpe_A1002 3.2e-127 383.0 COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VIKD@28216|Betaproteobacteria,1KPGH@119065|unclassified Burkholderiales 28216|Betaproteobacteria K V4R - - - - - - - - - - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_12267_2 1122201.AUAZ01000065_gene3852 6.45e-137 398.0 COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,1S4Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain - - 1.14.15.23 ko:K22325 - - - - ko00000,ko01000 - - - Rieske k141_403_1 519989.ECTPHS_04708 3.76e-196 556.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1WVYU@135613|Chromatiales 135613|Chromatiales N ATPase FliI YscN family - - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k141_18496_1 1163409.UUA_15121 2.52e-95 294.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria,1X3EX@135614|Xanthomonadales 135614|Xanthomonadales P COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) yehZ - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC k141_6620_1 279714.FuraDRAFT_2624 1.41e-110 345.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_4592_1 640081.Dsui_3258 2.78e-45 149.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,2VTSM@28216|Betaproteobacteria,2KWJF@206389|Rhodocyclales 206389|Rhodocyclales G Cupin - - - - - - - - - - - - Cupin_2 k141_4592_2 32057.KB217483_gene9700 2.28e-24 100.0 COG2020@1|root,COG2020@2|Bacteria,1G57G@1117|Cyanobacteria 1117|Cyanobacteria O PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - ICMT k141_3208_1 1328313.DS2_14334 3.35e-65 218.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,465T3@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases atzF - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase k141_21329_1 1049564.TevJSym_ab00030 1.2e-79 262.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1J4PP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG0591 Na proline symporter cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_404_1 194439.CT1683 1.74e-69 233.0 COG0474@1|root,COG0474@2|Bacteria 2|Bacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_8832_2 519989.ECTPHS_09974 5.94e-83 262.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 k141_15133_1 1288826.MSNKSG1_10558 2.36e-128 365.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,467CR@72275|Alteromonadaceae 1236|Gammaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU k141_15133_2 443152.MDG893_03015 2.58e-131 378.0 2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria,465TE@72275|Alteromonadaceae 1236|Gammaproteobacteria S 5'-nucleotidase - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5-nucleotidase k141_6722_1 765910.MARPU_15720 2.46e-17 84.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales 135613|Chromatiales S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_14387_1 1278309.KB907099_gene2386 5.12e-256 712.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XH8A@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_14387_2 1278309.KB907099_gene2387 7.17e-152 429.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XI7T@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_7501_2 1049564.TevJSym_bi00190 7.53e-94 295.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_4738_1 313596.RB2501_10922 2.03e-53 182.0 COG0457@1|root,COG2819@1|root,COG0457@2|Bacteria,COG2819@2|Bacteria,4NN8M@976|Bacteroidetes,1HZYT@117743|Flavobacteriia 976|Bacteroidetes S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase,TPR_8 k141_2583_1 1042375.AFPL01000046_gene1874 8.22e-18 82.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,4652P@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_2583_2 1121935.AQXX01000129_gene1828 3.9e-110 322.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,1XK58@135619|Oceanospirillales 135619|Oceanospirillales O Proteasome subunit - - - ko:K07395 - - - - ko00000 - - - Proteasome k141_2583_4 925775.XVE_4465 2.5e-33 117.0 COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,1S8SP@1236|Gammaproteobacteria,1X7H8@135614|Xanthomonadales 135614|Xanthomonadales T TIGRFAM phage conjugal plasmid C-4 type zinc finger protein, TraR family - - - - - - - - - - - - zf-dskA_traR k141_2583_5 1278309.KB907099_gene3068 0.0 1217.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XH4X@135619|Oceanospirillales 135619|Oceanospirillales C NADH flavin oxidoreductase NADH oxidase - - - - - - - - - - - - HI0933_like,Oxidored_FMN,Pyr_redox_2 k141_2583_6 1278309.KB907099_gene3069 3.43e-112 327.0 COG1309@1|root,COG1309@2|Bacteria,1R59A@1224|Proteobacteria,1S20U@1236|Gammaproteobacteria,1XJWP@135619|Oceanospirillales 135619|Oceanospirillales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_2583_7 1328313.DS2_15824 1.25e-68 216.0 COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,1S6W5@1236|Gammaproteobacteria,46878@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_N k141_2583_8 1348114.OM33_15195 1.16e-39 136.0 COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,1SCVF@1236|Gammaproteobacteria,2Q333@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_2583_9 1278309.KB907099_gene3071 1.09e-88 273.0 COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,1XS4E@135619|Oceanospirillales 135619|Oceanospirillales E Amino Acid - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k141_10273_2 1286106.MPL1_05384 2.28e-38 130.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales 72273|Thiotrichales H Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_10273_3 697282.Mettu_1388 7.79e-72 231.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XDYT@135618|Methylococcales 135618|Methylococcales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_18000_1 717772.THIAE_06725 1.51e-49 163.0 COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,460Z1@72273|Thiotrichales 72273|Thiotrichales S YaeQ - - - - - - - - - - - - YaeQ k141_18637_1 240015.ACP_1209 1.93e-46 159.0 COG4232@1|root,COG4232@2|Bacteria 2|Bacteria CO protein-disulfide reductase activity dsbD - 1.8.1.8 ko:K04084,ko:K06196 - - - - ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.2 - - DsbD,DsbD_2 k141_6062_2 857087.Metme_3732 5.69e-101 311.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XENA@135618|Methylococcales 135618|Methylococcales KLT kinase domain - - - - - - - - - - - - PP2C_2,Pkinase k141_8833_1 1238450.VIBNISOn1_1010019 8.34e-30 117.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1XT9F@135623|Vibrionales 135623|Vibrionales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k141_8243_1 1232683.ADIMK_1173 7.77e-74 235.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S43R@1236|Gammaproteobacteria,468AX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_7502_1 761193.Runsl_3570 2.61e-95 290.0 COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,47MSW@768503|Cytophagia 976|Bacteroidetes E Cys/Met metabolism PLP-dependent enzyme - - 2.6.1.109 ko:K19715 - - R11395 RC00160 ko00000,ko01000,ko01005 - - - DegT_DnrJ_EryC1 k141_5430_1 396588.Tgr7_0458 3.56e-93 294.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1WYS8@135613|Chromatiales 135613|Chromatiales KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - HAMP,HEAT_2,Pkinase,sCache_3_2 k141_5430_2 713586.KB900536_gene2578 3.17e-162 465.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - - - - - - - - - - T2SSE k141_5430_3 177437.HRM2_04990 2.92e-11 63.9 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MII7@213118|Desulfobacterales 28221|Deltaproteobacteria NU PFAM type II secretion system protein E - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_10274_1 1304275.C41B8_04476 5.55e-63 209.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr k141_1927_1 1278309.KB907100_gene2129 1.06e-143 426.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_9504_1 1278309.KB907103_gene1203 2.28e-186 552.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XNKT@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - - - - - - - - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C k141_9504_2 1278309.KB907103_gene1204 1.44e-108 325.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XH2Z@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_8834_1 663610.JQKO01000008_gene242 1.53e-41 142.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U7GY@28211|Alphaproteobacteria,3NBA0@45404|Beijerinckiaceae 28211|Alphaproteobacteria NU Type II secretion system (T2SS), protein G gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_6723_1 1266909.AUAG01000002_gene1262 4.27e-10 59.7 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXMA@135613|Chromatiales 135613|Chromatiales T Chemotaxis sensory transducer - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_6723_2 631362.Thi970DRAFT_01223 1.91e-36 142.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WX3E@135613|Chromatiales 135613|Chromatiales NT Methyl-accepting chemotaxis protein (MCP) signaling domain - - - - - - - - - - - - MCPsignal k141_7503_1 1027273.GZ77_05640 7.34e-59 190.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XHW1@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_17230_1 330214.NIDE0940 2.29e-17 80.1 COG3764@1|root,COG3764@2|Bacteria 2|Bacteria M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase k141_17230_3 713586.KB900536_gene1465 0.0 917.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1WVYF@135613|Chromatiales 135613|Chromatiales C pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k141_8244_2 1380387.JADM01000011_gene3596 1.58e-88 266.0 COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,1XIHT@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_13104_1 580332.Slit_1878 1.7e-37 135.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,2VJUY@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome c - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k141_13104_2 580332.Slit_1877 1.2e-50 170.0 COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,2VSFZ@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_10275_1 261292.Nit79A3_1155 1.18e-78 258.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,373XP@32003|Nitrosomonadales 28216|Betaproteobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_13798_2 1265313.HRUBRA_01754 1.03e-26 114.0 28MV3@1|root,2ZB2R@2|Bacteria,1N53J@1224|Proteobacteria,1SBDN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF560 k141_14388_1 1278307.KB906978_gene3820 4.94e-89 288.0 COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,GAF,GAF_2,Guanylate_cyc,PAS_9 k141_8835_1 396588.Tgr7_1000 6.53e-29 107.0 2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,1SDWS@1236|Gammaproteobacteria,1X22K@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2818) - - - - - - - - - - - - DUF2818 k141_8245_1 1459636.NTE_03552 2.1e-18 84.7 COG0123@1|root,arCOG00324@2157|Archaea 2157|Archaea BQ including yeast histone deacetylase and acetoin utilization protein - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl k141_8245_2 261292.Nit79A3_2778 1.1e-22 95.5 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,371N7@32003|Nitrosomonadales 28216|Betaproteobacteria H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_18638_1 1288826.MSNKSG1_12762 8.11e-66 211.0 COG5339@1|root,COG5339@2|Bacteria,1N902@1224|Proteobacteria 1224|Proteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 k141_18638_3 1288826.MSNKSG1_12752 5.03e-108 311.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,466Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0053,iSDY_1059.SDY_4064 CTP_transf_like k141_18638_4 1288826.MSNKSG1_12747 8.43e-35 130.0 COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,4660I@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_13105_1 1298593.TOL_0543 1.9e-34 119.0 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,1SDJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - k141_13105_2 1210884.HG799463_gene9842 3.76e-10 59.3 COG0789@1|root,COG0789@2|Bacteria,2J178@203682|Planctomycetes 203682|Planctomycetes K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR,MerR-DNA-bind k141_16531_1 1278309.KB907108_gene1549 7.33e-240 832.0 COG0771@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4347 k141_10276_1 391603.FBALC1_07323 0.00062 42.7 COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1HXBD@117743|Flavobacteriia 976|Bacteroidetes E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k141_19365_1 1278309.KB907105_gene1437 7.97e-82 251.0 COG0183@1|root,COG0183@2|Bacteria,1R6V1@1224|Proteobacteria,1S0V8@1236|Gammaproteobacteria,1XHFS@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - - - - - - - - - - - - k141_19365_2 1278309.KB907105_gene1436 5.76e-185 522.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1XJEB@135619|Oceanospirillales 135619|Oceanospirillales S Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA k141_19365_3 1278309.KB907105_gene1435 9.77e-280 774.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1XH6Z@135619|Oceanospirillales 135619|Oceanospirillales S glutamate--cysteine ligase - - - - - - - - - - - - - k141_19365_4 1278309.KB907105_gene1434 0.0 1233.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,1XRRY@135619|Oceanospirillales 135619|Oceanospirillales CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 k141_7504_1 314278.NB231_15223 3.5e-86 284.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_19989_1 1232683.ADIMK_3944 6.81e-111 353.0 COG0004@1|root,COG5001@1|root,COG0004@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K03320,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_17231_1 292415.Tbd_1852 6.25e-26 102.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria,1KRXX@119069|Hydrogenophilales 119069|Hydrogenophilales S Pfam:DUF989 - - - - - - - - - - - - Urate_ox_N k141_17231_2 1123279.ATUS01000001_gene1616 6.59e-52 177.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1J4QJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase B/oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_6724_1 640081.Dsui_0248 1.91e-37 139.0 28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,2KW9E@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF3025) - - - - - - - - - - - - DUF3025 k141_6066_1 1163617.SCD_n01864 3.66e-116 337.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_3340_1 1049564.TevJSym_aw00370 2.29e-40 136.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,1JAXW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur oxidation protein SoxZ soxZ - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ k141_18656_1 998674.ATTE01000001_gene2787 1.44e-76 240.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales 72273|Thiotrichales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_21478_1 1288826.MSNKSG1_11833 6.55e-100 298.0 2EBDF@1|root,335E4@2|Bacteria,1NH7B@1224|Proteobacteria,1SHGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21478_2 1288826.MSNKSG1_11828 4.61e-195 543.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1PQPU@1224|Proteobacteria,1RYEZ@1236|Gammaproteobacteria,464T5@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0835 Chemotaxis signal transduction protein cheV3 - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_21478_3 1288826.MSNKSG1_11823 2.63e-134 381.0 COG3932@1|root,COG3932@2|Bacteria,1N0FN@1224|Proteobacteria,1S4SJ@1236|Gammaproteobacteria,467N5@72275|Alteromonadaceae 1236|Gammaproteobacteria S ABC-type transport system, permease components - - - - - - - - - - - - ExoD k141_22139_1 1118235.CAJH01000020_gene1260 3.13e-23 92.0 COG2608@1|root,COG2608@2|Bacteria,1N95B@1224|Proteobacteria,1S6PK@1236|Gammaproteobacteria,1X8W8@135614|Xanthomonadales 135614|Xanthomonadales P Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein - - - - - - - - - - - - HMA k141_1940_1 1316936.K678_15566 1.27e-08 61.6 COG0642@1|root,COG3829@1|root,COG4191@1|root,COG5000@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2JQQV@204441|Rhodospirillales 204441|Rhodospirillales T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,PAS,PAS_4,PAS_7,PAS_9 k141_7522_2 1122599.AUGR01000017_gene2978 5.12e-39 132.0 COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria,1XKAN@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c - - - ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 - - Cytochrom_C k141_13813_1 1033802.SSPSH_001421 1.98e-16 79.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 40-residue YVTN family beta-propeller repeat pedA - - - - - - - - - - - Cytochrom_D1,Lactonase k141_10291_1 1305735.JAFT01000003_gene34 1.25e-06 52.4 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,2TRW8@28211|Alphaproteobacteria,2PFNS@252301|Oceanicola 28211|Alphaproteobacteria S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k141_8257_1 105559.Nwat_2894 9.04e-52 195.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg k141_15887_1 1485544.JQKP01000011_gene753 7.2e-18 89.7 COG3221@1|root,COG5001@1|root,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VZNB@28216|Betaproteobacteria,44W9B@713636|Nitrosomonadales 28216|Betaproteobacteria T ABC transporter, phosphonate, periplasmic substrate-binding protein - - - - - - - - - - - - EAL,GGDEF,PAS_8,Phosphonate-bd k141_13119_1 1122132.AQYH01000005_gene474 4.44e-42 154.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,4B9NZ@82115|Rhizobiaceae 28211|Alphaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k141_5438_1 1366050.N234_30860 1.56e-09 59.3 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2VK6Y@28216|Betaproteobacteria,1K1R8@119060|Burkholderiaceae 28216|Betaproteobacteria C oxidoreductase FAD NAD(P)-binding domain protein - - - ko:K21324 - - - - ko00000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_3472_1 1278309.KB907100_gene2054 6.95e-71 220.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1XI4M@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_3472_2 1042375.AFPL01000046_gene2010 2.44e-93 280.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,466EB@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_6811_2 1499686.BN1079_01134 4.93e-109 326.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k141_13936_1 743974.MBO_08462 8.23e-126 370.0 COG1403@1|root,COG1403@2|Bacteria,1MWNP@1224|Proteobacteria,1RPF2@1236|Gammaproteobacteria,3NMCE@468|Moraxellaceae 1236|Gammaproteobacteria V HNH endonuclease - - - - - - - - - - - - HNH_4 k141_18780_1 1288826.MSNKSG1_02073 8.55e-209 597.0 COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,1RMJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - - - - - - - - - - Peptidase_M19,Ricin_B_lectin k141_16654_1 743721.Psesu_2660 2.85e-25 114.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,1X535@135614|Xanthomonadales 135614|Xanthomonadales I LssY C-terminus - - - - - - - - - - - - LssY_C,PAP2,SNARE_assoc k141_16654_2 1269813.ATUL01000001_gene1047 6.35e-47 159.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,1WXGU@135613|Chromatiales 135613|Chromatiales S peptidase S16, lon - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_16654_3 523791.Kkor_0603 1.47e-15 73.6 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1XHWE@135619|Oceanospirillales 135619|Oceanospirillales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_6197_1 1247649.D560_0776 5.37e-47 166.0 COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,2VK1V@28216|Betaproteobacteria,3T266@506|Alcaligenaceae 28216|Betaproteobacteria EGP Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_6197_2 1123400.KB904813_gene3039 2.13e-20 87.4 COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria 1236|Gammaproteobacteria T membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF347 k141_3473_1 1156919.QWC_21914 1.29e-48 176.0 COG0769@1|root,COG0770@1|root,COG0769@2|Bacteria,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,3T2I5@506|Alcaligenaceae 28216|Betaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murF - 6.3.2.10,6.3.2.13 ko:K01929,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_3473_2 1120980.JQKH01000074_gene874 9.56e-06 48.1 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,2KQ1I@206351|Neisseriales 206351|Neisseriales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_11147_1 1278309.KB907100_gene2070 2.28e-100 296.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1XISU@135619|Oceanospirillales 135619|Oceanospirillales IQ KR domain - - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 k141_11147_2 1278309.KB907100_gene2069 1.08e-89 278.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria,1XIYZ@135619|Oceanospirillales 135619|Oceanospirillales G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_14527_1 1122201.AUAZ01000027_gene2207 2.98e-48 163.0 COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,1RNA4@1236|Gammaproteobacteria,466V1@72275|Alteromonadaceae 1236|Gammaproteobacteria C Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 vanB - 1.1.1.404 ko:K03863,ko:K21607 ko00361,ko00627,ko01100,ko01120,map00361,map00627,map01100,map01120 - R05274,R11585 RC00392,RC01533 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_14527_2 1122201.AUAZ01000027_gene2206 1.74e-231 639.0 COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,1RQ8W@1236|Gammaproteobacteria,46A0H@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rieske [2Fe-2S] domain vanA - 1.14.13.82 ko:K03862 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001,ko01000 - - - Rieske k141_2720_1 519989.ECTPHS_11010 2.5e-81 256.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales 135613|Chromatiales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_645_1 292563.Cyast_0028 1.15e-15 84.7 COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg,dCache_1 k141_645_2 1328313.DS2_03175 1.15e-22 89.7 COG1251@1|root,COG1251@2|Bacteria,1NHAA@1224|Proteobacteria,1SJH6@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - - - - - - - - - - Fer2_BFD k141_5554_1 1268622.AVS7_00629 0.000134 43.5 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,4AEBG@80864|Comamonadaceae 28216|Betaproteobacteria K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_5554_2 686340.Metal_1078 1.02e-69 217.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XF2E@135618|Methylococcales 135618|Methylococcales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_11148_1 388401.RB2150_05743 8.54e-90 268.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,3ZGTV@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_20043_1 935863.AWZR01000007_gene264 2.53e-08 50.8 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1T0G6@1236|Gammaproteobacteria,1XC8H@135614|Xanthomonadales 135614|Xanthomonadales H ThiS family - - - - - - - - - - - - ThiS k141_20837_1 754477.Q7C_148 7.92e-81 268.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM aminopeptidase N, Escherichia coli type pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_6227_1 633131.TR2A62_2863 9.83e-23 92.8 COG1011@1|root,COG1011@2|Bacteria,1RHAB@1224|Proteobacteria,2U7PV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolase (HAD superfamily) - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase k141_6227_2 439496.RBY4I_3753 3.57e-151 439.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,2TSG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes sthA - 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_7631_1 697282.Mettu_0298 1.54e-15 73.2 2AUTZ@1|root,31KH1@2|Bacteria,1QIC9@1224|Proteobacteria,1TG6N@1236|Gammaproteobacteria,1XFT8@135618|Methylococcales 135618|Methylococcales S PilZ domain - - - - - - - - - - - - PilZ k141_7631_2 34506.g6321 3.54e-63 214.0 COG0249@1|root,COG3177@1|root,KOG0217@2759|Eukaryota,KOG3824@2759|Eukaryota,3ANI3@33154|Opisthokonta,3C14T@33208|Metazoa,3E5Y8@33213|Bilateria 33208|Metazoa L MutS domain I - - - - - - - - - - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_16682_1 631362.Thi970DRAFT_04963 1.92e-85 267.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1WWAI@135613|Chromatiales 135613|Chromatiales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran k141_2033_1 1472716.KBK24_0123045 7.73e-45 174.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,2VTF9@28216|Betaproteobacteria,1K0XB@119060|Burkholderiaceae 28216|Betaproteobacteria I Phosphoesterase PA-phosphatase related yabI_1 - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - LssY_C,PAP2,SNARE_assoc k141_8995_1 935567.JAES01000045_gene2572 1.16e-61 197.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1X6FV@135614|Xanthomonadales 135614|Xanthomonadales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k141_7632_1 1168065.DOK_11389 1.38e-29 118.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1J4IT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675 RsgA_GTPase k141_4035_1 396588.Tgr7_2014 4.64e-233 647.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1WW43@135613|Chromatiales 135613|Chromatiales J TIGRFAM Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k141_4035_2 472759.Nhal_2316 3.46e-05 45.1 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1WX5I@135613|Chromatiales 135613|Chromatiales J Belongs to the SUA5 family - - - - - - - - - - - - Sua5_yciO_yrdC k141_15215_1 1116472.MGMO_37c00170 3.06e-64 206.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XDWR@135618|Methylococcales 135618|Methylococcales D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_5567_1 153948.NAL212_0390 9.98e-27 101.0 COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2VTAR@28216|Betaproteobacteria,374IE@32003|Nitrosomonadales 28216|Betaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_5567_2 1266914.ATUK01000001_gene762 2.07e-33 119.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc k141_11762_1 870187.Thini_2017 2.58e-64 199.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,460J4@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_6228_2 322710.Avin_37770 4.21e-25 104.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,1S7SZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_8996_1 582744.Msip34_1550 9.51e-57 186.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,2KKMI@206350|Nitrosomonadales 206350|Nitrosomonadales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_18797_1 472759.Nhal_3561 1.98e-210 590.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_17370_1 1278309.KB907099_gene2813 4.75e-288 804.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria,1XHVF@135619|Oceanospirillales 135619|Oceanospirillales CK FMN_bind - - - - - - - - - - - - FMN_bind,Fer4_5 k141_17370_2 1278309.KB907099_gene2812 9.58e-90 271.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XHIK@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_7633_2 395961.Cyan7425_3178 1.5e-11 67.4 COG2199@1|root,COG3707@1|root,COG2199@2|Bacteria,COG3707@2|Bacteria,1GHDT@1117|Cyanobacteria 1117|Cyanobacteria T Diguanylate cyclase (GGDEF domain) - - - - - - - - - - - - GGDEF,PAS,PAS_4,Response_reg k141_20838_1 1415778.JQMM01000001_gene471 7.61e-202 580.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,1J9D3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria KQ Sigma-54 interaction domain - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_16683_1 1122134.KB893650_gene450 3.94e-42 142.0 COG3278@1|root,COG3278@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_665_1 1121940.AUDZ01000005_gene1972 2.63e-28 107.0 COG0500@1|root,COG0500@2|Bacteria,1QWS3@1224|Proteobacteria,1T4VS@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_31 k141_665_2 1163617.SCD_n01205 1.67e-152 446.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2VHFE@28216|Betaproteobacteria 28216|Betaproteobacteria P Chloride channel clcA - - - - - - - - - - - Voltage_CLC k141_19474_1 1288826.MSNKSG1_08348 1.47e-32 115.0 COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,468FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG3190 Flagellar biogenesis protein fliO - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_19474_2 1288826.MSNKSG1_08353 1.98e-75 229.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,467MM@72275|Alteromonadaceae 1236|Gammaproteobacteria N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C,FliN_N k141_19474_3 1288826.MSNKSG1_08358 5.5e-237 652.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,464P6@72275|Alteromonadaceae 1236|Gammaproteobacteria N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_19474_4 1288826.MSNKSG1_08363 5.11e-105 304.0 COG1580@1|root,COG1580@2|Bacteria,1N2N9@1224|Proteobacteria,1SAF0@1236|Gammaproteobacteria,468ID@72275|Alteromonadaceae 1236|Gammaproteobacteria N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_19474_5 1288826.MSNKSG1_08368 9.54e-224 624.0 COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,4679U@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar hook-length control protein fliK GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_19474_6 1288826.MSNKSG1_08373 2.16e-68 207.0 COG2198@1|root,COG2198@2|Bacteria,1NBYP@1224|Proteobacteria,1SCGW@1236|Gammaproteobacteria,4690D@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2198 FOG HPt domain hptB - - ko:K20976 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - Hpt k141_19474_7 1288826.MSNKSG1_08378 0.0 1147.0 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,4650J@72275|Alteromonadaceae 1236|Gammaproteobacteria T response regulator rsbU - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_19474_8 1288826.MSNKSG1_08383 6.14e-66 200.0 COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria,468IN@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) rsbV - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS_2 k141_19474_9 1288826.MSNKSG1_08388 5.25e-80 239.0 COG2882@1|root,COG2882@2|Bacteria,1NHU4@1224|Proteobacteria,1SGCB@1236|Gammaproteobacteria,46966@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG2882 Flagellar biosynthesis chaperone - - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_19474_10 1288826.MSNKSG1_08393 0.0 887.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,465KY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N k141_19474_11 1288826.MSNKSG1_08398 6.28e-159 451.0 COG1317@1|root,COG1317@2|Bacteria,1N6G2@1224|Proteobacteria,1S9KA@1236|Gammaproteobacteria,468J5@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG1317 Flagellar biosynthesis type III secretory pathway protein fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH,Yae1_N k141_19474_12 1288826.MSNKSG1_08403 6.65e-236 650.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,46610@72275|Alteromonadaceae 1236|Gammaproteobacteria N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N k141_19474_13 1288826.MSNKSG1_08408 0.0 1067.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,464NW@72275|Alteromonadaceae 1236|Gammaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_19474_14 1288826.MSNKSG1_08413 4.24e-76 228.0 COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,468DU@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE k141_19474_15 1288826.MSNKSG1_08418 0.0 894.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4647X@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_19474_16 1288826.MSNKSG1_08423 3.7e-279 765.0 COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,46D35@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation flrB - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_8 k141_6229_1 1249627.D779_2014 5.87e-81 248.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,1WVZ9@135613|Chromatiales 135613|Chromatiales S subfamily IA, variant 1 - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k141_2034_1 1123247.AUIJ01000010_gene176 2.78e-23 98.2 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_2034_2 999611.KI421504_gene1915 2.33e-133 386.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,280UB@191028|Leisingera 28211|Alphaproteobacteria C ATP synthase atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_17371_1 406818.XBJ1_0610 1.21e-121 364.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iUTI89_1310.UTI89_C0210 HGTP_anticodon,tRNA-synt_2b,tRNA_edit k141_15216_1 1278309.KB907101_gene641 9.88e-09 62.8 2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria,1XMCG@135619|Oceanospirillales 135619|Oceanospirillales S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV k141_21598_1 697282.Mettu_0998 2.34e-46 166.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1XDRN@135618|Methylococcales 135618|Methylococcales P PFAM NnrS - - - ko:K07234 - - - - ko00000 - - - NnrS k141_21598_2 1535422.ND16A_0338 0.00031 42.4 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_18799_1 1278309.KB907106_gene1377 1.14e-110 325.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XJHK@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_5568_1 207954.MED92_13568 1.52e-86 258.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XIW0@135619|Oceanospirillales 135619|Oceanospirillales H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k141_5568_2 999549.KI421513_gene2180 1.22e-62 201.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,2U7DM@28211|Alphaproteobacteria,281Y5@191028|Leisingera 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase csgA - - - - - - - - - - - adh_short,adh_short_C2 k141_17372_1 1163617.SCD_n00399 2.05e-109 326.0 COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria 28216|Betaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K01696,ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_16684_1 1266925.JHVX01000009_gene28 9.02e-08 54.3 COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,2WFIE@28216|Betaproteobacteria,372YN@32003|Nitrosomonadales 28216|Betaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k141_16684_2 643473.KB235930_gene2196 7.59e-06 52.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1G027@1117|Cyanobacteria,1HQJZ@1161|Nostocales 1117|Cyanobacteria T Hpt domain - - - - - - - - - - - - Hpt,Response_reg,Trans_reg_C k141_16684_3 1117647.M5M_13630 9.8e-49 172.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1J4CS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_15217_1 1123276.KB893248_gene41 1.13e-09 60.1 COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,47JGK@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory helix-turn-helix protein, lysR family oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_15217_2 1123278.KB893447_gene5596 3.95e-36 135.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_668_1 991905.SL003B_1127 9.7e-26 107.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TRZE@28211|Alphaproteobacteria,4BT9D@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_11764_1 1036674.A28LD_1899 1.02e-06 49.7 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,2QFUS@267893|Idiomarinaceae 1236|Gammaproteobacteria S Displays ATPase and GTPase activities rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_11764_2 472759.Nhal_0329 3.16e-43 145.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1WYYD@135613|Chromatiales 135613|Chromatiales G system, fructose subfamily IIA component - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man k141_11764_3 1286106.MPL1_01692 7.62e-32 113.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,461HK@72273|Thiotrichales 72273|Thiotrichales G TIGRFAM Phosphotransferase System HPr (HPr) Family - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_2739_1 207954.MED92_09541 3.59e-26 108.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RYFX@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF k141_2739_2 1040983.AXAE01000004_gene834 7.98e-36 129.0 COG3915@1|root,COG3915@2|Bacteria,1RHJS@1224|Proteobacteria,2U8BH@28211|Alphaproteobacteria,43KRG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - Oxidored_molyb k141_2739_3 1397527.Q670_14170 3.55e-57 180.0 COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,1S60C@1236|Gammaproteobacteria,1XKQ9@135619|Oceanospirillales 135619|Oceanospirillales E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase k141_19620_1 519989.ECTPHS_13223 2.69e-114 364.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_18941_1 395493.BegalDRAFT_0035 1.03e-49 166.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,45ZUU@72273|Thiotrichales 72273|Thiotrichales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_2187_1 1265505.ATUG01000001_gene4660 5.67e-70 221.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria,2MJ76@213118|Desulfobacterales 28221|Deltaproteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT k141_2187_2 1123073.KB899242_gene963 4.54e-17 80.9 COG1638@1|root,COG1638@2|Bacteria,1PBU6@1224|Proteobacteria,1RXK0@1236|Gammaproteobacteria,1X5NG@135614|Xanthomonadales 135614|Xanthomonadales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_2891_1 396588.Tgr7_1065 2.72e-129 379.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Aldo keto - - - - - - - - - - - - Aldo_ket_red k141_6372_1 857087.Metme_3185 7.54e-50 178.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XE0Q@135618|Methylococcales 135618|Methylococcales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_7797_1 491952.Mar181_0423 1.73e-12 65.9 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XHZW@135619|Oceanospirillales 135619|Oceanospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_7797_2 391615.ABSJ01000034_gene1081 7.6e-118 339.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1J4UQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0131 Imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iUMNK88_1353.UMNK88_2570 Hydrolase_like,IGPD,PNK3P k141_21076_1 314345.SPV1_00095 7.16e-69 234.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_12658_1 317025.Tcr_1804 1.5e-117 348.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria,4624H@72273|Thiotrichales 72273|Thiotrichales I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_11302_1 326423.RBAM_036870 2.17e-14 75.1 COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus 91061|Bacilli I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_11302_2 583345.Mmol_0415 1.45e-51 171.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VKHF@28216|Betaproteobacteria,2KP6B@206350|Nitrosomonadales 206350|Nitrosomonadales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_19621_2 545276.KB898727_gene422 5.14e-28 109.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,1WY6B@135613|Chromatiales 135613|Chromatiales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_2188_1 1278309.KB907099_gene2763 2.74e-60 186.0 COG1034@1|root,COG1034@2|Bacteria,1N72X@1224|Proteobacteria,1T35I@1236|Gammaproteobacteria,1XM6C@135619|Oceanospirillales 135619|Oceanospirillales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2_4 k141_2188_2 89187.ISM_01030 1.74e-08 55.1 COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,2TVYN@28211|Alphaproteobacteria,46RWZ@74030|Roseovarius 28211|Alphaproteobacteria C BFD-like [2Fe-2S] binding domain - - - - - - - - - - - - Fer2_BFD,Pyr_redox_2 k141_18942_1 396588.Tgr7_2631 6.87e-85 256.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1WWBK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_8477_2 156889.Mmc1_0695 2.11e-49 163.0 COG3311@1|root,COG3311@2|Bacteria,1R8IB@1224|Proteobacteria,2U5Z2@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_17 k141_8477_3 1121904.ARBP01000070_gene5181 1.86e-24 97.4 COG1569@1|root,COG1569@2|Bacteria,4NQT0@976|Bacteroidetes,47RMU@768503|Cytophagia 976|Bacteroidetes S PIN domain - - - - - - - - - - - - PIN_3 k141_14766_1 1122992.CBQQ010000082_gene1468 7.1e-85 295.0 COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,2FRC8@200643|Bacteroidia 976|Bacteroidetes M RHS repeat-associated core domain protein - - - - - - - - - - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_16125_1 498211.CJA_3399 4.04e-73 234.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1FFRG@10|Cellvibrio 1236|Gammaproteobacteria T Bacterial regulatory protein, Fis family prsR - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_7076_1 1278309.KB907100_gene1851 4.4e-125 367.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XHQS@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_7076_2 1278309.KB907100_gene1850 9.16e-63 192.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1XKM3@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF1820 k141_7076_3 1278309.KB907100_gene1849 4.13e-56 179.0 COG3152@1|root,COG3152@2|Bacteria,1QECQ@1224|Proteobacteria,1SHDJ@1236|Gammaproteobacteria,1XPWC@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 k141_17514_1 243233.MCA2441 4.46e-71 216.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1THNZ@1236|Gammaproteobacteria,1XF4B@135618|Methylococcales 135618|Methylococcales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF k141_17514_2 189753.AXAS01000002_gene5213 3.18e-131 392.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2TQX6@28211|Alphaproteobacteria,3JTAC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G FGGY family of carbohydrate kinases, C-terminal domain - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_17514_3 1042375.AFPL01000044_gene1274 3.33e-35 130.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,4671M@72275|Alteromonadaceae 1236|Gammaproteobacteria E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - ko:K06203 - - - - ko00000 - - iJR904.b2413,iYL1228.KPN_02760 EI24 k141_4286_2 1121935.AQXX01000119_gene4761 4.22e-100 296.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XHZW@135619|Oceanospirillales 135619|Oceanospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_4286_3 2340.JV46_18570 2.79e-117 338.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1J4UQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0131 Imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iUMNK88_1353.UMNK88_2570 Hydrolase_like,IGPD,PNK3P k141_4286_4 1208321.D104_17100 2.95e-13 68.6 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1XHPV@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator anr - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_13367_1 1439940.BAY1663_00759 2.09e-54 207.0 COG2198@1|root,COG2198@2|Bacteria,1NFSM@1224|Proteobacteria,1SI4G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - Hpt k141_11975_1 640081.Dsui_1801 4.1e-36 132.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VPQ9@28216|Betaproteobacteria,2M01K@206389|Rhodocyclales 206389|Rhodocyclales D ATPase MipZ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - CbiA k141_2892_1 765914.ThisiDRAFT_0584 2.46e-87 274.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_2189_1 697282.Mettu_2822 5.15e-37 140.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1XDSN@135618|Methylococcales 135618|Methylococcales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_2189_2 243159.AFE_0895 6.3e-36 131.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,2NCS3@225057|Acidithiobacillales 225057|Acidithiobacillales H Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_21077_1 1282356.H045_12510 3.61e-49 170.0 COG2199@1|root,COG3706@2|Bacteria,1RDI8@1224|Proteobacteria,1S436@1236|Gammaproteobacteria,1YP25@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_12659_1 1278309.KB907104_gene957 5.45e-55 181.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1XJSY@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_8478_1 1205908.AKXW01000114_gene1668 4.18e-80 258.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1XV69@135623|Vibrionales 135623|Vibrionales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1 - - Na_H_Exchanger,TrkA_N k141_18237_1 472759.Nhal_3421 3.91e-58 191.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1WXVZ@135613|Chromatiales 135613|Chromatiales C Belongs to the AlaDH PNT family - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_18237_2 1163408.UU9_00480 4.14e-41 159.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1X4F7@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein ftsk ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - Cupin_4,FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_2190_1 388401.RB2150_06398 3e-12 65.9 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,3ZGB5@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k141_2190_2 1469613.JT55_13615 1.22e-29 109.0 COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,3FDEQ@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function (DUF1489) MA20_36070 - - - - - - - - - - - DUF1489 k141_7799_1 443152.MDG893_07660 1.58e-105 318.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,4641R@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14061_1 1049564.TevJSym_bn00150 4.04e-17 79.3 COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) - - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6 k141_14061_2 1123399.AQVE01000001_gene488 6.25e-36 134.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,45ZMM@72273|Thiotrichales 72273|Thiotrichales F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_18944_2 1198232.CYCME_1600 1.19e-89 268.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,462J2@72273|Thiotrichales 72273|Thiotrichales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_809_1 1208321.D104_11045 1.17e-86 267.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales 135619|Oceanospirillales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_4287_1 1288826.MSNKSG1_06623 3.29e-231 642.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,464G9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1977 Anth_synt_I_N,Chorismate_bind k141_11976_1 1236959.BAMT01000006_gene380 1.79e-57 199.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KKM5@206350|Nitrosomonadales 206350|Nitrosomonadales S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48,TPR_19 k141_20359_1 1127673.GLIP_2924 7.96e-101 311.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9863_2 999141.GME_06380 6.08e-89 270.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1XJDT@135619|Oceanospirillales 135619|Oceanospirillales T transcriptional regulator - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_9863_3 349521.HCH_06084 4.95e-115 350.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XJ2S@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase envZ - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_20378_1 1123399.AQVE01000007_gene1137 9.17e-159 463.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - - - - - - - - - - STAS,Sulfate_transp k141_4309_1 42565.FP66_14955 1.27e-94 289.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1XH9D@135619|Oceanospirillales 135619|Oceanospirillales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB k141_4309_2 290400.Jann_0535 5.97e-07 50.8 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_17536_1 765912.Thimo_3276 3.82e-65 209.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_10591_1 1040989.AWZU01000007_gene719 1.48e-60 196.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2TRJM@28211|Alphaproteobacteria,3JTTW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA k141_9163_1 314282.PCNPT3_01165 1.92e-55 185.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,2QHFP@267894|Psychromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family oxyR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_7095_1 472759.Nhal_0500 0.0 1056.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k141_7095_2 1237149.C900_01411 6.76e-70 227.0 COG2843@1|root,COG2843@2|Bacteria,4NI6J@976|Bacteroidetes,47NKK@768503|Cytophagia 976|Bacteroidetes M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap k141_3620_1 857087.Metme_2457 4.59e-131 375.0 COG1733@1|root,COG1733@2|Bacteria,1PGWN@1224|Proteobacteria,1SXVP@1236|Gammaproteobacteria,1XGTB@135618|Methylococcales 135618|Methylococcales K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_3620_2 857087.Metme_2458 9.01e-35 119.0 COG1942@1|root,COG1942@2|Bacteria,1NBW3@1224|Proteobacteria,1SECR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 4-oxalocrotonate tautomerase - - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase k141_3620_3 765420.OSCT_2825 2.63e-31 139.0 COG5001@1|root,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi,3762V@32061|Chloroflexia 32061|Chloroflexia T PFAM GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_8 k141_3620_4 743720.Psefu_2859 1.49e-30 112.0 COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1TBXD@1236|Gammaproteobacteria,1YYV3@136845|Pseudomonas putida group 1236|Gammaproteobacteria G 5-carboxymethyl-2-hydroxymuconate isomerase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - CHMI k141_3620_5 104623.Ser39006_04089 3.83e-104 306.0 COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,1S226@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 k141_1513_1 342610.Patl_3885 1.12e-52 173.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols mhpB - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB k141_1513_2 13690.CP98_02707 7.2e-57 179.0 COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,2U5U7@28211|Alphaproteobacteria,2K4SD@204457|Sphingomonadales 204457|Sphingomonadales S Protocatechuate 4,5-dioxygenase - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA k141_16144_1 545264.KB898754_gene1828 6.32e-78 244.0 COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,1S09K@1236|Gammaproteobacteria,1WX6Q@135613|Chromatiales 135613|Chromatiales S PFAM DMSO reductase anchor subunit (DmsC) - - - ko:K21309 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 - - - DmsC k141_13381_1 395493.BegalDRAFT_3457 1.07e-59 196.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,45ZYD@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM k141_9864_1 1122137.AQXF01000002_gene132 2.08e-102 326.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_17537_1 555793.WSK_2725 1.4e-68 233.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,2K088@204457|Sphingomonadales 204457|Sphingomonadales Q Cytochrome p450 - - - - - - - - - - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_7817_2 221288.JH992901_gene2610 8.96e-11 57.0 28UR4@1|root,2ZGVF@2|Bacteria,1GFWN@1117|Cyanobacteria,1JMMZ@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_4310_1 395493.BegalDRAFT_3252 1e-08 57.0 COG0642@1|root,COG2199@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,46228@72273|Thiotrichales 72273|Thiotrichales T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_4310_2 519989.ECTPHS_03874 1.31e-73 222.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02657 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_21094_2 748247.AZKH_3325 1.92e-82 282.0 COG0745@1|root,COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZXD@206389|Rhodocyclales 206389|Rhodocyclales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS_4,Response_reg k141_2208_1 1245471.PCA10_46820 3.94e-29 119.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE31@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase bifA - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS_3 k141_2208_2 743720.Psefu_2953 3.14e-100 304.0 COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF2167 k141_93_1 388401.RB2150_02434 3.45e-84 261.0 COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2TRYK@28211|Alphaproteobacteria,3ZH1C@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Belongs to the beta-ketoacyl-ACP synthases family fabF1 - - ko:K14660 - - - - ko00000,ko01000 - - - Ketoacyl-synt_C,ketoacyl-synt k141_93_2 391593.RCCS2_01094 2.36e-14 67.4 COG0236@1|root,COG0236@2|Bacteria,1MZVG@1224|Proteobacteria,2UC3Q@28211|Alphaproteobacteria,2P3S6@2433|Roseobacter 28211|Alphaproteobacteria IQ COG0236 Acyl carrier protein - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding k141_18966_1 1288826.MSNKSG1_06833 8.51e-288 792.0 COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C eight transmembrane protein EpsH - - - - - - - - - - - - DUF3485,Exosortase_EpsH k141_2915_2 395494.Galf_2858 5.48e-22 95.9 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VJS8@28216|Betaproteobacteria 28216|Betaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_9164_1 1278309.KB907102_gene20 1.94e-55 182.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XH3I@135619|Oceanospirillales 135619|Oceanospirillales M UDP-glucose 4-epimerase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_9164_2 1278309.KB907102_gene19 3.59e-43 147.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XJKB@135619|Oceanospirillales 135619|Oceanospirillales P nucleotidase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_16855_1 1316927.ATKI01000040_gene2626 2.61e-11 60.8 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,1YQIK@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria O Sulfur carrier protein which probably makes part of a sulfur-relay system tusA GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_16855_2 1283284.AZUK01000002_gene2796 2.15e-45 161.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP synthase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_6389_1 765911.Thivi_1898 3.65e-244 706.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1WXAA@135613|Chromatiales 135613|Chromatiales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_16145_1 1088868.CIN_10750 2.14e-07 53.1 COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,2JRPT@204441|Rhodospirillales 204441|Rhodospirillales L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_16145_2 568768.CM001975_gene2282 1.14e-18 85.5 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,2JDEG@204037|Dickeya 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_5840_15 1197951.I6S6K3_9CAUD 3.81e-13 81.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k141_16280_2 1278309.KB907101_gene288 1.17e-26 102.0 COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,1XK5Y@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_278_1 396588.Tgr7_3085 4.98e-169 482.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RR0P@1236|Gammaproteobacteria,1X0E3@135613|Chromatiales 135613|Chromatiales E PFAM glutamine synthetase catalytic region - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_14918_1 1353529.M899_1409 7.72e-17 86.3 COG2227@1|root,COG2227@2|Bacteria,1PEUM@1224|Proteobacteria,42VXF@68525|delta/epsilon subdivisions,2MUGQ@213481|Bdellovibrionales,2X20Q@28221|Deltaproteobacteria 213481|Bdellovibrionales H Methionine biosynthesis protein MetW - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - - k141_14918_2 886293.Sinac_2483 2.26e-10 63.2 COG0438@1|root,COG0438@2|Bacteria,2J117@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_7994_1 1278309.KB907108_gene1627 9.02e-56 185.0 COG0253@1|root,COG0253@2|Bacteria,1R68H@1224|Proteobacteria,1RYYA@1236|Gammaproteobacteria,1XNU5@135619|Oceanospirillales 135619|Oceanospirillales E Diaminopimelate epimerase - - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_17729_1 743299.Acife_2164 1.12e-06 51.6 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,2NCI2@225057|Acidithiobacillales 225057|Acidithiobacillales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k141_17729_2 1165096.ARWF01000001_gene1813 9e-167 478.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,2KKU8@206350|Nitrosomonadales 206350|Nitrosomonadales F Belongs to the dGTPase family. Type 2 subfamily - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_18406_1 323848.Nmul_A2313 3.11e-84 266.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,371WH@32003|Nitrosomonadales 28216|Betaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_21907_1 1288826.MSNKSG1_14162 2.03e-33 122.0 COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,1SBT6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent) - - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans k141_21907_2 1288826.MSNKSG1_14167 8.93e-102 310.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein ctpH - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_982_2 272630.MexAM1_META1p2399 4.66e-08 55.8 COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2U65Q@28211|Alphaproteobacteria,1JX3B@119045|Methylobacteriaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_7266_1 1049564.TevJSym_an00600 1.23e-132 386.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1J543@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k141_15623_1 1333856.L686_22505 1.09e-123 364.0 COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,1RYUT@1236|Gammaproteobacteria,1Z0FQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Heme d1 biosynthesis protein NirF nirF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K19345 - - - - ko00000 - - - Cytochrom_D1 k141_15623_2 1123392.AQWL01000002_gene1770 2.98e-46 160.0 COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2VHP8@28216|Betaproteobacteria,1KT7B@119069|Hydrogenophilales 119069|Hydrogenophilales K COG1522 Transcriptional regulators - - - - - - - - - - - - - k141_15623_3 713586.KB900536_gene2307 2.04e-33 121.0 COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,1S620@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG1522 Transcriptional regulators nirL - - - - - - - - - - - HTH_AsnC-type k141_279_1 1163617.SCD_n02604 2.59e-74 238.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2VH45@28216|Betaproteobacteria 28216|Betaproteobacteria P Sulfate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,STAS_2,Sulfate_transp k141_12139_1 794903.OPIT5_29970 4.56e-16 77.0 COG2995@1|root,COG2995@2|Bacteria,46YQG@74201|Verrucomicrobia,3KA02@414999|Opitutae 414999|Opitutae S Paraquat-inducible protein A - - - ko:K03808 - - - - ko00000 - - - PqiA k141_12139_2 1144319.PMI16_02085 1.27e-12 68.9 COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VNYN@28216|Betaproteobacteria,4733Q@75682|Oxalobacteraceae 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 k141_21908_2 545276.KB898731_gene2152 1.91e-45 155.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales 135613|Chromatiales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_1705_3 867900.Celly_1468 1.19e-40 147.0 2DD47@1|root,32U0V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_14919_2 511062.GU3_07835 3.15e-52 171.0 COG3090@1|root,COG3090@2|Bacteria,1RFS4@1224|Proteobacteria,1S4VU@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_14919_3 1122201.AUAZ01000027_gene2187 7.61e-14 71.2 COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1S03A@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP k141_12844_1 1288826.MSNKSG1_16061 4.8e-85 263.0 COG4590@1|root,COG4590@2|Bacteria,1MW7Q@1224|Proteobacteria,1S6QR@1236|Gammaproteobacteria,46BWI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - - k141_12844_2 1288826.MSNKSG1_16066 1.4e-194 540.0 COG1414@1|root,COG1414@2|Bacteria,1MXRJ@1224|Proteobacteria,1S251@1236|Gammaproteobacteria,46AQY@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1414 Transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR k141_2344_1 1313421.JHBV01000025_gene1029 6.77e-51 197.0 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,1IVGR@117747|Sphingobacteriia 976|Bacteroidetes T PAS fold - - - - - - - - - - - - CHASE3,GAF,HATPase_c,HNOBA,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k141_2344_2 1122194.AUHU01000015_gene2994 7.59e-58 191.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_7995_2 765914.ThisiDRAFT_0180 4.82e-128 380.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_17730_1 743721.Psesu_1928 1.76e-12 74.3 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_3775_1 998674.ATTE01000001_gene1086 1.82e-80 261.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales 72273|Thiotrichales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_6508_1 1288826.MSNKSG1_00011 0.0 992.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,464RE@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0066 HMGL-like,LeuA_dimer k141_14920_1 189753.AXAS01000078_gene6582 5.23e-53 180.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,3JT1R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Pyridine nucleotide-disulphide oxidoreductase - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 k141_21909_2 177437.HRM2_34530 1.02e-50 166.0 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,42R31@68525|delta/epsilon subdivisions,2WN6I@28221|Deltaproteobacteria,2MJMJ@213118|Desulfobacterales 28221|Deltaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k141_281_1 1168067.JAGP01000001_gene444 1.41e-44 154.0 COG1577@1|root,COG1577@2|Bacteria,1RIKN@1224|Proteobacteria,1S678@1236|Gammaproteobacteria,46285@72273|Thiotrichales 72273|Thiotrichales I GHMP kinases N terminal domain - - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N k141_281_2 1123514.KB905899_gene453 8.97e-23 97.1 COG1577@1|root,COG1577@2|Bacteria,1NF04@1224|Proteobacteria,1RPXQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I GHMP kinases N terminal domain - - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k141_12141_1 1123393.KB891326_gene13 7.62e-54 174.0 COG1416@1|root,COG1416@2|Bacteria,1NAV2@1224|Proteobacteria 1224|Proteobacteria - - - - - ko:K09004 - - - - ko00000 - - - DrsE k141_12845_1 396588.Tgr7_2196 1.43e-76 241.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales 135613|Chromatiales C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD k141_7996_1 1278073.MYSTI_00871 5.74e-90 278.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2WIV0@28221|Deltaproteobacteria,2YU7E@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the UPF0061 (SELO) family - - - ko:K08997 - - - - ko00000 - - - UPF0061 k141_20552_1 1278309.KB907099_gene3098 9.33e-229 639.0 28JFR@1|root,2Z99N@2|Bacteria,1R7C5@1224|Proteobacteria,1RZYU@1236|Gammaproteobacteria,1XJ6G@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20552_2 1121430.JMLG01000025_gene110 2.4e-07 52.4 COG3707@1|root,COG3707@2|Bacteria,1U6TA@1239|Firmicutes,24G9P@186801|Clostridia,261NT@186807|Peptococcaceae 186801|Clostridia T response regulator receiver - - - ko:K22010 - M00839 - - ko00000,ko00002,ko02022 - - - ANTAR,Response_reg k141_18408_1 1397527.Q670_16240 1.79e-22 106.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,1XRXC@135619|Oceanospirillales 135619|Oceanospirillales S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_17731_1 1122137.AQXF01000005_gene1223 4.76e-17 80.9 COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,2TUJD@28211|Alphaproteobacteria 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_17731_2 1122137.AQXF01000005_gene1222 4.96e-89 266.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC transporter - - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran k141_3095_1 1026882.MAMP_01949 7.3e-255 728.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM aminopeptidase N, Escherichia coli type pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_21910_1 497964.CfE428DRAFT_0708 1.77e-21 95.1 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,46Z7W@74201|Verrucomicrobia 74201|Verrucomicrobia T SMART PAS domain containing protein - - - - - - - - - - - - HATPase_c,Response_reg k141_21910_2 292415.Tbd_1192 1.55e-45 150.0 COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria,1KT24@119069|Hydrogenophilales 119069|Hydrogenophilales T cheY-homologous receiver domain - - - ko:K02485 - - - - ko00000,ko02022 - - - Response_reg k141_5862_1 1279015.KB908467_gene481 2.8e-24 103.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1Y3IJ@135624|Aeromonadales 135624|Aeromonadales U General secretion pathway protein F exeF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_5862_2 511062.GU3_02120 6.78e-244 689.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1Y3U5@135624|Aeromonadales 135624|Aeromonadales NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB exeE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_16281_2 1232683.ADIMK_0778 3.03e-174 502.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,46DB9@72275|Alteromonadaceae 1236|Gammaproteobacteria T V4R - - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - GAF_2,GGDEF,HTH_8,Sigma54_activat,V4R,XylR_N k141_12143_2 488538.SAR116_1656 3.73e-37 132.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,4BQ2Z@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_2346_1 1123393.KB891327_gene473 5.99e-87 259.0 COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,2WE8S@28216|Betaproteobacteria,1KSAI@119069|Hydrogenophilales 119069|Hydrogenophilales S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_18409_1 247633.GP2143_15881 1.17e-41 155.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1J5CT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EQ Hydantoinase/oxoprolinase hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A k141_20553_1 1123269.NX02_16445 1.46e-59 203.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2U43Z@28211|Alphaproteobacteria,2K2RG@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N k141_7997_1 243233.MCA0071 1.07e-42 146.0 COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales 135618|Methylococcales S pfam ammecr1 - - - - - - - - - - - - AMMECR1 k141_7997_2 768671.ThimaDRAFT_4173 1.39e-101 302.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales 135613|Chromatiales S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo k141_5141_1 243233.MCA2737 5.5e-21 87.8 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria,1XFBV@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - k141_5141_2 1265503.KB905160_gene2369 1.91e-18 86.3 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1N9PE@1224|Proteobacteria 1224|Proteobacteria T PAS fold - - - - - - - - - - - - PAS_4 k141_5863_1 292415.Tbd_2109 3.56e-23 94.0 2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,2W41I@28216|Betaproteobacteria,1KTCV@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_3096_1 1288826.MSNKSG1_13862 1.32e-81 254.0 COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae 1236|Gammaproteobacteria C acetyl-CoA hydrolase scpC GO:0003674,GO:0003824,GO:0003986,GO:0006082,GO:0006083,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008410,GO:0008775,GO:0009987,GO:0016289,GO:0016740,GO:0016782,GO:0016787,GO:0016788,GO:0016790,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043821,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0071704 2.8.3.18 ko:K18118,ko:K22214 ko00020,ko00620,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00640,map00650,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R10343,R11773 RC00012,RC00014 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_3040,iECSE_1348.ECSE_3182,iECW_1372.ECW_m3175,iEKO11_1354.EKO11_0812,iWFL_1372.ECW_m3175 AcetylCoA_hyd_C,AcetylCoA_hydro k141_3096_2 1288826.MSNKSG1_13867 2.24e-163 469.0 COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,4643R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1705) - - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1705,Sulfatase k141_7998_1 501479.ACNW01000058_gene4416 4.3e-71 230.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Cysteine synthase - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - Glutaredoxin,PALP k141_19141_1 765911.Thivi_3397 4.13e-111 331.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RX39@1236|Gammaproteobacteria,1WXEH@135613|Chromatiales 135613|Chromatiales U Part of a membrane complex involved in electron transport - - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_20554_1 323261.Noc_0189 3.18e-23 100.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1WWDC@135613|Chromatiales 135613|Chromatiales F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_5864_1 266809.PM03_00035 1.03e-111 328.0 COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,2TS8Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG4175 ABC-type proline glycine betaine transport system ATPase component proV - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS k141_3776_2 517722.AEUE01000001_gene2455 1.13e-34 125.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales 204457|Sphingomonadales S FeS assembly SUF system protein - - - - - - - - - - - - FeS_assembly_P k141_3776_3 768671.ThimaDRAFT_2141 6.38e-45 147.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1WYM7@135613|Chromatiales 135613|Chromatiales S Belongs to the HesB IscA family - - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_12144_1 1278309.KB907106_gene1376 2.04e-157 446.0 COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,1SZSC@1236|Gammaproteobacteria,1XRNW@135619|Oceanospirillales 135619|Oceanospirillales H NAD synthase - - - - - - - - - - - - NAD_synthase k141_2348_1 1234364.AMSF01000027_gene3464 2.22e-82 274.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1X5VX@135614|Xanthomonadales 135614|Xanthomonadales U haemagglutination activity domain - - - - - - - - - - - - ESPR,Glug,Haemagg_act k141_10768_1 1288826.MSNKSG1_14047 0.0 1068.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,465MZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N k141_10768_2 1288826.MSNKSG1_14052 1.93e-48 154.0 2E3CN@1|root,32YBX@2|Bacteria,1N716@1224|Proteobacteria,1SEFN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10768_3 1288826.MSNKSG1_14057 1.5e-156 439.0 COG2132@1|root,COG2132@2|Bacteria,1QUX3@1224|Proteobacteria,1S7ZQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Domain of unknown function (DUF4396) - - - - - - - - - - - - DUF4396 k141_10768_4 1288826.MSNKSG1_14062 9.79e-31 109.0 2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8173_1 1120977.JHUX01000007_gene160 3.04e-22 94.4 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,3NJ55@468|Moraxellaceae 1236|Gammaproteobacteria G Peptidyl-prolyl cis-trans fkpB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_8173_2 157783.LK03_02335 2.57e-162 461.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria 1236|Gammaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 LYTB k141_8173_3 1123279.ATUS01000003_gene528 3.05e-16 73.6 2DIKV@1|root,303K3@2|Bacteria,1PI5E@1224|Proteobacteria,1TFEX@1236|Gammaproteobacteria,1JBJH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 k141_462_1 631362.Thi970DRAFT_04215 1.13e-105 309.0 COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria,1WWUG@135613|Chromatiales 135613|Chromatiales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_18541_1 1121271.AUCM01000001_gene3530 9.6e-27 102.0 COG0589@1|root,COG0589@2|Bacteria,1RHZG@1224|Proteobacteria,2U792@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins uspF - - - - - - - - - - - Usp k141_11586_1 472759.Nhal_2796 8.28e-69 214.0 COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1WW3H@135613|Chromatiales 135613|Chromatiales S Converts GTP to 7,8-dihydroneopterin triphosphate folE2 - 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GCHY-1 k141_11586_2 1122207.MUS1_13720 2.33e-31 115.0 2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,1SATY@1236|Gammaproteobacteria,1XM06@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_11586_3 2340.JV46_20480 5.07e-69 213.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1J67X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA k141_21391_1 1278309.KB907101_gene454 7.64e-109 330.0 COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,1RPF4@1236|Gammaproteobacteria,1XRH8@135619|Oceanospirillales 135619|Oceanospirillales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - - - - - - - - - - MCPsignal k141_20667_1 1049564.TevJSym_ap00790 8.9e-19 87.8 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1J5PD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_13025_1 46429.BV95_02167 1.16e-44 152.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2K02T@204457|Sphingomonadales 204457|Sphingomonadales S Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols - - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB k141_19924_1 1278309.KB907105_gene1448 7.87e-40 140.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XIGU@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_19924_2 1278309.KB907105_gene1449 4.05e-61 191.0 2E1FM@1|root,32WU8@2|Bacteria,1N0AM@1224|Proteobacteria,1SBDV@1236|Gammaproteobacteria,1XMB3@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_19924_3 1278309.KB907105_gene1450 2.8e-77 231.0 2EU93@1|root,33MRI@2|Bacteria,1N7AW@1224|Proteobacteria,1SE4D@1236|Gammaproteobacteria,1XMH0@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_19924_4 1278309.KB907105_gene1451 5.54e-38 130.0 2ERYW@1|root,33JI1@2|Bacteria,1NIJI@1224|Proteobacteria,1SJ4V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19924_5 1278309.KB907105_gene1452 5.47e-162 457.0 COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1XJ5W@135619|Oceanospirillales 135619|Oceanospirillales Q rRNA (Guanine-N1-)-methyltransferase - - 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25 k141_19924_6 1278309.KB907105_gene1453 1.68e-258 710.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XH2P@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k141_19924_7 1278309.KB907105_gene1454 3.64e-227 628.0 COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,1XI70@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep_2,THDPS_M,THDPS_N k141_19924_8 765913.ThidrDRAFT_4443 2.7e-41 139.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,1WYR9@135613|Chromatiales 135613|Chromatiales P Belongs to the ArsC family - - - - - - - - - - - - ArsC k141_19924_9 1278309.KB907105_gene1456 1.91e-111 330.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1XIJ0@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate dapC - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12333_2 1123393.KB891317_gene2444 7.58e-42 141.0 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,1KRU2@119069|Hydrogenophilales 119069|Hydrogenophilales S Invasion gene expression up-regulator, SirB - - - - - - - - - - - - SirB k141_12333_3 135651.CBN32638 0.000396 44.7 KOG1418@1|root,KOG1418@2759|Eukaryota,3AH71@33154|Opisthokonta,3BZ3I@33208|Metazoa,3DE5Q@33213|Bilateria,40FYC@6231|Nematoda,1KY9E@119089|Chromadorea,40TTZ@6236|Rhabditida 33208|Metazoa P Ion channel - - - ko:K20007 - - - - ko00000,ko04040 1.A.1.18.1 - - Ion_trans_2 k141_7413_1 247633.GP2143_15176 4.39e-26 105.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_13710_1 1278309.KB907110_gene3208 6.52e-135 387.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XHJW@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the cysteine synthase cystathionine beta- synthase family cysM - 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_13710_2 1122599.AUGR01000023_gene4137 9.1e-39 133.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XKU7@135619|Oceanospirillales 135619|Oceanospirillales I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS k141_14333_1 264462.Bd3072 8.74e-28 115.0 COG2114@1|root,COG2114@2|Bacteria,1PEUH@1224|Proteobacteria,437J2@68525|delta/epsilon subdivisions,2MTTY@213481|Bdellovibrionales,2X2SU@28221|Deltaproteobacteria 213481|Bdellovibrionales T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc k141_463_1 1415778.JQMM01000001_gene58 5.67e-80 256.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1J5AY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG0608 Single-stranded DNA-specific exonuclease recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_17896_1 1278309.KB907103_gene1169 1.75e-108 315.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,1RNXB@1236|Gammaproteobacteria,1XHNK@135619|Oceanospirillales 135619|Oceanospirillales I transferase scoA - 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k141_17896_2 1278309.KB907103_gene1170 1.38e-184 517.0 COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RMVV@1236|Gammaproteobacteria,1XIT1@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K17737 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_17896_3 1278309.KB907103_gene1171 1.21e-108 315.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1XJ6U@135619|Oceanospirillales 135619|Oceanospirillales Q COG1335 Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_17896_4 1278309.KB907103_gene1172 8.58e-184 521.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XJ26@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_5333_1 1026882.MAMP_01177 3.22e-08 53.9 COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,1RMRQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Glutamate synthase - - 2.1.1.21 ko:K22082 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - GXGXG k141_5333_2 1042375.AFPL01000046_gene1893 1.08e-169 479.0 COG0034@1|root,COG0034@2|Bacteria,1MWHP@1224|Proteobacteria,1RMGF@1236|Gammaproteobacteria 1236|Gammaproteobacteria F glutamine amidotransferase - - 2.1.1.21 ko:K22081 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - GATase_6 k141_5333_3 1122201.AUAZ01000034_gene3501 2.74e-275 758.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RR0P@1236|Gammaproteobacteria,464S1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glutamine synthetase, catalytic domain glnT - 6.3.1.11,6.3.1.2 ko:K01915,ko:K09470 ko00220,ko00250,ko00330,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00330,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 M00136 R00253,R07414 RC00010,RC00090,RC00096,RC02798 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Gln-synt_C k141_5333_4 1042375.AFPL01000046_gene1900 3.57e-70 216.0 COG1396@1|root,COG1396@2|Bacteria,1MVQY@1224|Proteobacteria,1S0N1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional - - - - - - - - - - - - Cupin_2,HTH_3 k141_10184_1 1278309.KB907101_gene779 8.55e-150 429.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHKS@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_10184_3 1278309.KB907101_gene777 3.71e-156 440.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1XHUP@135619|Oceanospirillales 135619|Oceanospirillales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_10184_4 1278309.KB907101_gene776 3.54e-39 138.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1XII5@135619|Oceanospirillales 135619|Oceanospirillales I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k141_17150_2 588581.Cpap_0635 5.57e-07 53.9 COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia,3WJZT@541000|Ruminococcaceae 186801|Clostridia N TIGRFAM flagellar export protein FliJ fliJ - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_11587_1 156578.ATW7_15764 1.52e-29 116.0 COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1SR53@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - - k141_17909_1 1278309.KB907103_gene1184 2.17e-184 515.0 COG0596@1|root,COG0596@2|Bacteria,1REY5@1224|Proteobacteria,1S4UP@1236|Gammaproteobacteria,1XIQK@135619|Oceanospirillales 135619|Oceanospirillales S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_6 k141_17909_2 1278309.KB907103_gene1183 1.18e-173 497.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBD@135619|Oceanospirillales 135619|Oceanospirillales EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_5359_1 983545.Glaag_2500 6.64e-71 222.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,4662X@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain uvrY GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_16461_1 1288826.MSNKSG1_02073 1.15e-236 671.0 COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,1RMJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - - - - - - - - - - Peptidase_M19,Ricin_B_lectin k141_16461_3 1318628.MARLIPOL_02590 7.15e-29 107.0 2CJZ1@1|root,33KZZ@2|Bacteria,1NPZD@1224|Proteobacteria,1SJAB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16461_4 1288826.MSNKSG1_02058 0.0 1043.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF k141_16461_5 1219072.VHA01S_003_00630 4.22e-33 125.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RQ9K@1236|Gammaproteobacteria,1XVXA@135623|Vibrionales 135623|Vibrionales C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N k141_7438_1 1297742.A176_06712 6.63e-64 209.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k141_20685_1 1122929.KB908218_gene1515 6.81e-22 99.0 COG4763@1|root,COG4763@2|Bacteria,1Q61M@1224|Proteobacteria,2TR19@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyltransferase 3 - - - - - - - - - - - - Acyl_transf_3 k141_5993_1 413404.Rmag_0224 2.62e-42 143.0 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,1RRM7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_2523_1 1268068.PG5_16320 2.69e-62 206.0 COG0612@1|root,COG0612@2|Bacteria,1MVSB@1224|Proteobacteria,1SA4C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase, M16 - - - - - - - - - - - - - k141_10206_1 926551.KB900707_gene599 1.07e-50 175.0 COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia,1ERF7@1016|Capnocytophaga 976|Bacteroidetes H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_17172_1 1288826.MSNKSG1_12222 1.03e-181 516.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4649C@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the GARS family purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 GARS_A,GARS_C,GARS_N k141_17172_2 1298865.H978DRAFT_3615 1.33e-86 271.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS k141_1856_1 395493.BegalDRAFT_1886 2.79e-75 229.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,460DI@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 k141_8772_1 105559.Nwat_0670 1.35e-59 199.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales 135613|Chromatiales T PFAM MucB RseB - - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C k141_8772_3 105559.Nwat_0672 6.27e-31 122.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_6679_1 395494.Galf_1865 3.58e-57 199.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,44VAG@713636|Nitrosomonadales 28216|Betaproteobacteria I Acyl-CoA dehydrogenase, N-terminal domain fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_3917_1 1232683.ADIMK_4119 5.45e-105 314.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,1RMBC@1236|Gammaproteobacteria,46AP4@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_8 k141_16462_1 396588.Tgr7_0039 3.44e-46 167.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RWW8@1236|Gammaproteobacteria,1X085@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_3283_1 1122201.AUAZ01000014_gene233 3.89e-16 80.5 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,469PA@72275|Alteromonadaceae 1236|Gammaproteobacteria T PEP-utilising enzyme, N-terminal ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08483,ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_3283_2 1333507.AUTQ01000119_gene1805 3.61e-58 186.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,2Q17D@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S MgtC family mgtC GO:0008150,GO:0009405,GO:0044419,GO:0051704 - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_3283_3 870967.VIS19158_01934 5.76e-149 433.0 COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,1RP1J@1236|Gammaproteobacteria,1XV5B@135623|Vibrionales 135623|Vibrionales S DUF1704 - - - - - - - - - - - - DUF1704 k141_1190_1 1131814.JAFO01000001_gene4319 3.98e-17 79.3 COG1355@1|root,COG1355@2|Bacteria,1R369@1224|Proteobacteria,2TZYM@28211|Alphaproteobacteria,3F257@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.16,1.13.11.8 ko:K04101,ko:K05713 ko00360,ko00362,ko00624,ko00627,ko01120,ko01220,map00360,map00362,map00624,map00627,map01120,map01220 M00545 R01632,R03550,R04280,R04376,R06788,R09565 RC00233,RC00387,RC00535,RC01140,RC01364,RC02567,RC02694 br01602,ko00000,ko00001,ko00002,ko01000 - - - LigB k141_1190_2 1278309.KB907099_gene2569 1.18e-35 130.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,1XJT7@135619|Oceanospirillales 135619|Oceanospirillales S auxin efflux carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_9445_1 713586.KB900536_gene1719 1.27e-59 187.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k141_9445_2 572477.Alvin_0607 3.87e-44 151.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,1WW6W@135613|Chromatiales 135613|Chromatiales E subfamily IA, variant 3 - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD,HAD_2,Hydrolase k141_17910_1 927677.ALVU02000001_gene3042 6.09e-40 155.0 COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GR84@1117|Cyanobacteria,1H639@1142|Synechocystis 2|Bacteria T AAA ATPase domain - - - - - - - - - - - - AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,HisKA_3,PAS_4,PAS_9,Pkinase,Response_reg k141_13730_1 1288826.MSNKSG1_17516 1.26e-149 448.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,4643M@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0591 Na proline symporter cbrA - - - - - - - - - - - HATPase_c,HisKA,PAS k141_13730_2 1288826.MSNKSG1_17511 8.96e-317 865.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,464AY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains cbrB - - - - - - - - - - - Response_reg,Sigma54_activat k141_13730_3 1288826.MSNKSG1_17506 9.4e-317 864.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,464KY@72275|Alteromonadaceae 1236|Gammaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_13730_4 1288826.MSNKSG1_17501 1.06e-108 314.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,467BR@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 HPPK k141_13730_5 1288826.MSNKSG1_17496 1.83e-185 516.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,464SP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_13730_6 1288826.MSNKSG1_17491 1.79e-70 219.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,46494@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144 Pantoate_ligase k141_15067_1 1286106.MPL1_05384 1.97e-15 70.5 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales 72273|Thiotrichales H Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_15067_2 754476.Q7A_2836 3.57e-216 602.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,4602K@72273|Thiotrichales 72273|Thiotrichales D TIGRFAM Cell shape determining protein MreB Mrl - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k141_15067_3 395493.BegalDRAFT_1662 6.33e-79 246.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,460NI@72273|Thiotrichales 72273|Thiotrichales M Involved in formation and maintenance of cell shape - - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC k141_15067_4 595494.Tola_0255 6.47e-33 121.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1Y4ND@135624|Aeromonadales 135624|Aeromonadales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD k141_15067_5 393595.ABO_1955 5.23e-09 58.2 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XHM0@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase k141_12347_1 1278309.KB907110_gene3188 8.64e-122 354.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1XHJM@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_12347_2 1278309.KB907110_gene3187 2.54e-101 302.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1XHJT@135619|Oceanospirillales 135619|Oceanospirillales C 1-deoxy-D-xylulose-5-phosphate synthase - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_3284_1 754476.Q7A_334 2.75e-44 157.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,45ZRP@72273|Thiotrichales 72273|Thiotrichales S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 k141_20686_1 319795.Dgeo_1793 1.72e-14 80.1 COG1305@1|root,COG1721@1|root,COG1305@2|Bacteria,COG1721@2|Bacteria 2|Bacteria E protein (some members contain a von Willebrand factor type A (vWA) domain tgpA - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,DUF58,Transglut_core k141_4672_1 755732.Fluta_3618 6.28e-56 185.0 COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,1I8SQ@117743|Flavobacteriia,2PARW@246874|Cryomorphaceae 976|Bacteroidetes E NeuB family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_4672_2 1408433.JHXV01000021_gene1635 2.4e-74 234.0 COG0036@1|root,COG0517@1|root,COG0036@2|Bacteria,COG0517@2|Bacteria,4PBW2@976|Bacteroidetes,1ICPN@117743|Flavobacteriia,2PBIW@246874|Cryomorphaceae 976|Bacteroidetes G Ribulose-phosphate 3 epimerase family - - - - - - - - - - - - Ribul_P_3_epim k141_1191_1 1049564.TevJSym_av00170 6.33e-103 311.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1J547@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iEC042_1314.EC042_2616 tRNA-synt_1c k141_481_1 1296415.JACC01000008_gene2342 1.12e-06 60.1 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,1I4Q5@117743|Flavobacteriia 976|Bacteroidetes L AAA domain - - - - - - - - - - - - AAA_11,AAA_12,DUF2726 k141_7621_1 1123255.JHYS01000017_gene1390 3.71e-36 135.0 COG0477@1|root,COG2814@2|Bacteria,1R8UR@1224|Proteobacteria,2VVAT@28216|Betaproteobacteria,4AFUP@80864|Comamonadaceae 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr k141_8976_1 1158762.KB898037_gene2482 0.00013 46.6 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_16672_1 1288826.MSNKSG1_08143 1.83e-250 732.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_2021_1 1150469.RSPPHO_03277 8.65e-15 72.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k141_8977_1 393305.YE0637 2.34e-82 267.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,41DVG@629|Yersinia 1236|Gammaproteobacteria L to DNA damage-inducible DNA polymerase II of Proteobacteria UniRef RepID A4W6G4_ENT38 polB GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k141_652_1 1278309.KB907101_gene787 4.58e-215 597.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1XIPA@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N k141_652_2 1278309.KB907101_gene788 6.95e-74 223.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XJR3@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_652_3 1123228.AUIH01000014_gene260 2.43e-300 827.0 COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria,1XHSQ@135619|Oceanospirillales 135619|Oceanospirillales C Na H antiporter - - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter k141_6216_1 998674.ATTE01000001_gene2269 1.42e-104 308.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,45ZU2@72273|Thiotrichales 72273|Thiotrichales J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 k141_5560_1 1278309.KB907106_gene1239 5.44e-73 221.0 COG1580@1|root,COG1580@2|Bacteria,1ND67@1224|Proteobacteria,1SDZM@1236|Gammaproteobacteria,1XKJJ@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar basal body-associated protein FliL - - - - - - - - - - - - FliL k141_5560_2 1278309.KB907106_gene1238 2.33e-89 264.0 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,1XJP0@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the Rsd AlgQ family - - - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_5560_3 1278309.KB907106_gene1237 1.25e-142 412.0 COG2319@1|root,COG2319@2|Bacteria,1PDT0@1224|Proteobacteria,1RV85@1236|Gammaproteobacteria,1XIAA@135619|Oceanospirillales 135619|Oceanospirillales S WD40 repeats - - - - - - - - - - - - WD40 k141_5560_4 1232683.ADIMK_2043 3.83e-59 190.0 293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,1S4U7@1236|Gammaproteobacteria,467DI@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5560_5 1042375.AFPL01000036_gene3044 2.64e-112 328.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,4665Z@72275|Alteromonadaceae 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_8978_1 1278309.KB907099_gene2996 1.3e-111 333.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI11@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_7622_1 365044.Pnap_0278 9.53e-98 296.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,4ACKU@80864|Comamonadaceae 28216|Betaproteobacteria NU PFAM Type II secretion system protein E pilT - - ko:K02669,ko:K12203 - - - - ko00000,ko02035,ko02044 3.A.15.2,3.A.7.10.1,3.A.7.9.1 - - T2SSE k141_7622_2 713586.KB900536_gene2578 1.73e-92 282.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - - - - - - - - - - T2SSE k141_9652_1 1288826.MSNKSG1_17551 1.13e-211 604.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46410@72275|Alteromonadaceae 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_9652_2 1288826.MSNKSG1_17546 4.52e-85 265.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,46A56@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_11750_1 1288826.MSNKSG1_13507 1.82e-179 503.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,465UN@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_11750_2 1288826.MSNKSG1_13512 3.33e-116 333.0 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S3Y2@1236|Gammaproteobacteria,46AX8@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG2065 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran k141_11750_3 1288826.MSNKSG1_13517 1.42e-100 291.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,466VN@72275|Alteromonadaceae 1236|Gammaproteobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX k141_11750_4 1288826.MSNKSG1_13522 1.18e-132 376.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,466MP@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the UPF0301 (AlgH) family yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_11750_5 1288826.MSNKSG1_13527 1.79e-171 482.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,465SW@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes tonB3 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_11750_6 1288826.MSNKSG1_13532 1.39e-227 627.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,4651A@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k141_11750_7 1288826.MSNKSG1_13537 9.74e-88 258.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,466ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver pilG - - ko:K02657,ko:K03413 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_11750_8 1288826.MSNKSG1_13542 2.29e-79 236.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,467AE@72275|Alteromonadaceae 1236|Gammaproteobacteria KT COG0784 FOG CheY-like receiver pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_11750_9 1288826.MSNKSG1_13547 7.14e-126 358.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,467KR@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0835 Chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_11750_10 1288826.MSNKSG1_13552 0.0 1050.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465M4@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_11750_11 1288826.MSNKSG1_13557 1.95e-218 602.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RQ5E@1236|Gammaproteobacteria,466CU@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG1352 Methylase of chemotaxis methyl-accepting proteins pilK - 2.1.1.80 ko:K00575,ko:K02661 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035,ko02044 - - - CheR,CheR_N k141_11750_12 1288826.MSNKSG1_13562 7.23e-102 328.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4650G@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_2023_1 1286093.C266_04739 1.56e-20 94.4 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,2VNIP@28216|Betaproteobacteria,1K4QQ@119060|Burkholderiaceae 28216|Betaproteobacteria K PFAM helix-turn-helix- domain containing protein AraC type - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC k141_654_1 1342301.JASD01000008_gene2067 5.02e-117 357.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3ZVIF@60136|Sulfitobacter 28211|Alphaproteobacteria E Belongs to the GcvT family dmgdh2 - 1.5.8.4 ko:K00315 ko00260,ko01100,map00260,map01100 - R01565 RC00181 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C k141_2729_1 1278309.KB907102_gene212 0.0 918.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XHGP@135619|Oceanospirillales 135619|Oceanospirillales S ATPase components of ABC transporters with duplicated ATPase domains - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_2729_2 1278309.KB907102_gene213 8.14e-72 219.0 COG0782@1|root,COG0782@2|Bacteria,1MZNI@1224|Proteobacteria,1SED1@1236|Gammaproteobacteria,1XM18@135619|Oceanospirillales 135619|Oceanospirillales K Elongation factor - - - - - - - - - - - - GreA_GreB k141_2729_3 1278309.KB907102_gene214 3.25e-105 304.0 COG1047@1|root,COG1047@2|Bacteria,1RGXG@1224|Proteobacteria,1S6XS@1236|Gammaproteobacteria,1XJVV@135619|Oceanospirillales 135619|Oceanospirillales G Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_2729_4 1278309.KB907102_gene215 4.42e-217 605.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,1RMZV@1236|Gammaproteobacteria,1XS66@135619|Oceanospirillales 135619|Oceanospirillales O OsmC-like protein - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC k141_7623_1 1318628.MARLIPOL_10731 1.16e-07 52.8 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,46868@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - k141_7623_2 715451.ambt_21710 2.53e-56 186.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,463XT@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein required for cytochrome oxidase assembly ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k141_8979_1 391619.PGA1_c33780 9.43e-94 279.0 COG2267@1|root,COG2267@2|Bacteria,1P7JV@1224|Proteobacteria,2TUWY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_5561_2 498211.CJA_2170 3.21e-45 165.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1FGPJ@10|Cellvibrio 1236|Gammaproteobacteria E Domain of unknown function (DUF3458_C) ARM repeats pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_6218_1 395494.Galf_1865 7.75e-80 264.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,44VAG@713636|Nitrosomonadales 28216|Betaproteobacteria I Acyl-CoA dehydrogenase, N-terminal domain fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_6814_1 214092.YPO0013 1.28e-21 91.3 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,41DGJ@629|Yersinia 1236|Gammaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_2604,iEcHS_1320.EcHS_A4080,iEcolC_1368.EcolC_4158,iLF82_1304.LF82_1370,iNRG857_1313.NRG857_19230,iSBO_1134.SBO_3869,iSbBS512_1146.SbBS512_E4329,iUMNK88_1353.UMNK88_4686,ic_1306.c4801 NTP_transf_3 k141_6814_2 29908.U7PN06 1.87e-07 58.2 COG1132@1|root,KOG0055@2759|Eukaryota,38E88@33154|Opisthokonta,3NU2T@4751|Fungi,3QJNT@4890|Ascomycota,217P9@147550|Sordariomycetes,3UQK4@5151|Ophiostomatales 4751|Fungi Q ABC transporter transmembrane region - - 3.6.3.44 ko:K05658 ko02010,ko04976,ko05206,ko05226,map02010,map04976,map05206,map05226 - - - ko00000,ko00001,ko01000,ko02000,ko04090,ko04147 3.A.1.201 - - ABC_membrane,ABC_tran k141_17361_1 1278309.KB907099_gene3006 1.04e-97 291.0 COG0583@1|root,COG0583@2|Bacteria,1QU1H@1224|Proteobacteria,1RYFY@1236|Gammaproteobacteria,1XH6S@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_17361_2 1278309.KB907099_gene3005 1.24e-199 553.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1XIHJ@135619|Oceanospirillales 135619|Oceanospirillales EH Amino-transferase class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_17361_3 1278309.KB907099_gene3004 7.07e-80 242.0 COG3172@1|root,COG3172@2|Bacteria 2|Bacteria H ATPase kinase involved in NAD metabolism nadR - - - - - - - - - - - AAA_28 k141_4027_2 1278309.KB907100_gene2039 2.85e-186 524.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XH3J@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK k141_16674_1 1232683.ADIMK_0443 5.87e-70 220.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,4661X@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k141_16674_2 1278309.KB907104_gene865 2.99e-128 365.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XH6R@135619|Oceanospirillales 135619|Oceanospirillales EH with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_16674_3 981327.F925_02146 9.49e-09 55.8 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RN9X@1236|Gammaproteobacteria,3NIM5@468|Moraxellaceae 1236|Gammaproteobacteria C Oxidoreductase FAD-binding domain benC GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.25,1.18.1.7 ko:K05784,ko:K14581,ko:K16161 ko00362,ko00364,ko00622,ko00624,ko00626,ko00627,ko00633,ko00642,ko00680,ko01100,ko01120,ko01200,ko01220,map00362,map00364,map00622,map00624,map00626,map00627,map00633,map00642,map00680,map01100,map01120,map01200,map01220 M00174,M00534,M00551,M00638 R01142,R02968,R05290,R05291,R05422,R05423,R05424,R05425,R05426,R05427,R05428,R05621,R05622,R05665,R06909,R06930,R06937,R07704,R07706,R07709,R07710,R08100,R08101,R08108,R08109,R08110,R09159,R09233 RC00091,RC00098,RC00157,RC00173,RC00270,RC00274,RC00275,RC00490,RC01376,RC01377,RC01378,RC01450,RC01801,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_7624_1 666685.R2APBS1_0024 5.61e-70 232.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RWHB@1236|Gammaproteobacteria,1X3VE@135614|Xanthomonadales 135614|Xanthomonadales EU Dipeptidyl aminopeptidase acylaminoacyl peptidase - - - - - - - - - - - - PD40,Peptidase_S9 k141_10452_1 1278309.KB907105_gene1525 1.73e-14 72.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XHR4@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_10452_2 1278309.KB907105_gene1526 1.4e-192 545.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XI3S@135619|Oceanospirillales 135619|Oceanospirillales O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_10452_3 1278309.KB907105_gene1527 2.35e-162 459.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1XIEV@135619|Oceanospirillales 135619|Oceanospirillales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_10452_4 1278309.KB907105_gene1528 1.83e-35 120.0 COG3242@1|root,COG3242@2|Bacteria,1N9FC@1224|Proteobacteria,1SEP6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_10452_5 1278309.KB907105_gene1529 2.49e-246 681.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1XHUK@135619|Oceanospirillales 135619|Oceanospirillales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_2730_1 1168067.JAGP01000001_gene591 5.24e-90 272.0 COG1082@1|root,COG1082@2|Bacteria,1Q3WR@1224|Proteobacteria,1S04R@1236|Gammaproteobacteria,461MT@72273|Thiotrichales 72273|Thiotrichales G Xylose isomerase - - - - - - - - - - - - - k141_18789_1 1288826.MSNKSG1_13162 6.77e-128 372.0 COG0745@1|root,COG1639@1|root,COG0745@2|Bacteria,COG1639@2|Bacteria,1RCK9@1224|Proteobacteria,1S2FB@1236|Gammaproteobacteria,46BUY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0784 FOG CheY-like receiver - - - - - - - - - - - - HDOD,Response_reg k141_18789_2 225937.HP15_3429 2.1e-173 509.0 COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,46630@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,HDOD,Hpt,Response_reg k141_18789_3 1288826.MSNKSG1_13177 0.0 984.0 COG5002@1|root,COG5002@2|Bacteria,1QWCR@1224|Proteobacteria 1224|Proteobacteria T signal transduction Histidine kinase - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_20827_1 1122201.AUAZ01000005_gene514 5.37e-49 165.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,46786@72275|Alteromonadaceae 1236|Gammaproteobacteria P Rhodanese Homology Domain sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_2051_2 1278309.KB907100_gene1800 7.89e-141 399.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XJ7N@135619|Oceanospirillales 135619|Oceanospirillales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_2051_3 1278309.KB907100_gene1799 8.29e-162 459.0 COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,1XHWQ@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - ko:K08974 - - - - ko00000 - - - DUF368 k141_2051_4 1278309.KB907100_gene1798 1.12e-41 145.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XJ9X@135619|Oceanospirillales 135619|Oceanospirillales DM COG0739 Membrane proteins related to metalloendopeptidases nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_9025_1 414684.RC1_3430 9.25e-59 190.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,2JSRE@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_9673_1 713586.KB900536_gene2084 1.77e-76 234.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1WY2E@135613|Chromatiales 135613|Chromatiales S TIGRFAM DJ-1 family protein - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI k141_9673_2 187272.Mlg_2567 3.18e-64 208.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1X0WV@135613|Chromatiales 135613|Chromatiales S Divergent polysaccharide deacetylase - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 k141_20850_1 1278309.KB907107_gene1719 2.02e-59 201.0 COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1XKPC@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook-length control protein FliK fliK - - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook k141_6825_1 391593.RCCS2_02815 1.05e-18 87.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,2P1E7@2433|Roseobacter 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacC - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_6825_2 1188256.BASI01000005_gene1757 1.13e-37 131.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,3FDAA@34008|Rhodovulum 28211|Alphaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin k141_14561_1 1118235.CAJH01000013_gene785 0.000129 46.6 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1X4F8@135614|Xanthomonadales 135614|Xanthomonadales L glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_14561_2 396595.TK90_2485 1.87e-46 150.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales 135613|Chromatiales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic k141_6253_1 1255043.TVNIR_0316 1.3e-104 308.0 COG1018@1|root,COG1018@2|Bacteria,1R5YD@1224|Proteobacteria,1T2RI@1236|Gammaproteobacteria,1WY0W@135613|Chromatiales 135613|Chromatiales C PFAM Oxidoreductase FAD NAD(P)-binding - - 1.6.2.2 ko:K00326 ko00520,map00520 - R00100 - ko00000,ko00001,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_20068_1 717774.Marme_2814 1.24e-65 217.0 COG1196@1|root,COG1196@2|Bacteria,1PEPJ@1224|Proteobacteria,1RQFX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Domain of unknown function (DUF4041) - - - - - - - - - - - - DUF4041,MUG113,T5orf172 k141_6826_1 675813.VIB_000252 1.65e-06 55.1 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XSU6@135623|Vibrionales 135623|Vibrionales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k141_18805_1 1122929.KB908229_gene3367 6.29e-48 170.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2TQJW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narZ - 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_18805_2 388739.RSK20926_15201 4.56e-91 279.0 COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2V9Y8@28211|Alphaproteobacteria,2P2Q9@2433|Roseobacter 28211|Alphaproteobacteria C Respiratory nitrate reductase beta C-terminal - - 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Fer4_11,Nitr_red_bet_C k141_2052_1 713586.KB900536_gene1690 4.94e-70 238.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_19497_1 1278309.KB907102_gene81 4.16e-84 263.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XHC9@135619|Oceanospirillales 135619|Oceanospirillales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB pilB - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N k141_19497_2 754476.Q7A_1596 3.8e-39 135.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,461AT@72273|Thiotrichales 72273|Thiotrichales NU Belongs to the N-Me-Phe pilin family - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k141_19497_3 1278309.KB907102_gene83 2.88e-18 78.2 2CDA6@1|root,33HQN@2|Bacteria,1NNXM@1224|Proteobacteria,1SI1B@1236|Gammaproteobacteria,1XQBE@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9674_1 1333998.M2A_2001 4.45e-51 171.0 COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2U7CA@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG1136 ABC-type antimicrobial peptide transport system ATPase component bceA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_17396_1 1122201.AUAZ01000014_gene277 3.2e-148 430.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_17396_2 1232683.ADIMK_0095 3.3e-43 148.0 COG3090@1|root,COG3090@2|Bacteria,1MYII@1224|Proteobacteria,1S73D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_20069_1 1278309.KB907109_gene3283 4.1e-96 296.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1XHEE@135619|Oceanospirillales 135619|Oceanospirillales P Chloride channel - - - - - - - - - - - - CBS,Voltage_CLC k141_20851_2 396588.Tgr7_1848 7.52e-64 208.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales 135613|Chromatiales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_681_1 1278309.KB907103_gene1004 8.32e-102 296.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XJW7@135619|Oceanospirillales 135619|Oceanospirillales L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k141_681_2 1278309.KB907103_gene1003 0.0 1076.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1XH85@135619|Oceanospirillales 135619|Oceanospirillales J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k141_681_3 207954.MED92_08722 2.27e-36 124.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1XKYW@135619|Oceanospirillales 135619|Oceanospirillales S FmdB family transcriptional regulator - - - - - - - - - - - - Zn-ribbon_8 k141_681_4 1278309.KB907103_gene1001 1.14e-87 259.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1XKHG@135619|Oceanospirillales 135619|Oceanospirillales FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - - - - - - - - - - HIT k141_681_5 1278309.KB907103_gene1000 1.58e-30 117.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1XHRX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_2762_2 765912.Thimo_0820 5.04e-67 217.0 COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,1WZ29@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF599 - - - - - - - - - - - - DUF599 k141_6827_1 76114.ebA4360 3.8e-93 282.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2VKSA@28216|Betaproteobacteria,2KYDG@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF3641) - - - - - - - - - - - - DUF3641,Radical_SAM k141_3595_2 1127673.GLIP_1402 7.34e-45 147.0 COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,1SCGG@1236|Gammaproteobacteria,46CAN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1272) - - - ko:K09984 - - - - ko00000 - - - DUF1272 k141_3595_3 1278309.KB907099_gene3108 2.2e-77 235.0 COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,1S5RX@1236|Gammaproteobacteria,1XK2T@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DinB k141_3595_4 1278309.KB907099_gene3110 3.54e-211 592.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RRYY@1236|Gammaproteobacteria,1XHAZ@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_6365_1 377629.TERTU_1178 4.77e-43 155.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,2PMGQ@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H Fumarate reductase flavoprotein C-term nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_16115_1 1123514.KB905900_gene2057 1.15e-42 144.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,460QW@72273|Thiotrichales 72273|Thiotrichales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_16115_2 84531.JMTZ01000046_gene1054 7.19e-54 181.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1X2XQ@135614|Xanthomonadales 135614|Xanthomonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_799_1 1122201.AUAZ01000022_gene3133 8.64e-08 56.6 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 k141_19610_1 754477.Q7C_359 6.25e-102 313.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_2881_1 323261.Noc_2082 9.73e-118 349.0 COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,1RQ6N@1236|Gammaproteobacteria,1WWGR@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - ko:K02118 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N k141_11956_1 857087.Metme_0152 5.94e-35 126.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XE8S@135618|Methylococcales 135618|Methylococcales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_5709_1 1342302.JASC01000014_gene1921 5.2e-66 206.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,3ZVBD@60136|Sulfitobacter 28211|Alphaproteobacteria S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k141_16837_1 396513.SCA_1196 5.82e-05 45.8 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,4GXGI@90964|Staphylococcaceae 91061|Bacilli O COG1030 Membrane-bound serine protease (ClpP class) yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah k141_16837_2 153721.MYP_3874 3.48e-50 168.0 COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,47N8X@768503|Cytophagia 976|Bacteroidetes GM NAD dependent epimerase/dehydratase family - - - - - - - - - - - - Epimerase,NAD_binding_10 k141_9152_2 1249627.D779_3328 4.17e-42 147.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,1WXJH@135613|Chromatiales 135613|Chromatiales P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_14756_1 398580.Dshi_1396 9.78e-38 132.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k141_14756_2 1278073.MYSTI_06353 1.26e-13 69.7 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales 28221|Deltaproteobacteria I Biotin carboxylase accC - 6.3.4.14,6.4.1.1,6.4.1.2 ko:K01959,ko:K01961 ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230 M00082,M00173,M00376,M00620 R00344,R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_8484_1 1232683.ADIMK_0293 5.94e-78 240.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RZ4X@1236|Gammaproteobacteria,46A9A@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_8484_2 1122201.AUAZ01000001_gene2481 3.52e-79 247.0 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,1S7P2@1236|Gammaproteobacteria,46AF8@72275|Alteromonadaceae 1236|Gammaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_1498_1 395494.Galf_1200 1.18e-54 181.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,44VIF@713636|Nitrosomonadales 28216|Betaproteobacteria M Nucleotidyl transferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_7084_1 28229.ND2E_1802 1.18e-96 291.0 COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,1RRJE@1236|Gammaproteobacteria,2Q5XW@267889|Colwelliaceae 1236|Gammaproteobacteria E Putative serine dehydratase domain - - 4.1.2.42,4.1.3.41 ko:K18425,ko:K19967 - - - - ko00000,ko01000 - - - Ala_racemase_N,D-ser_dehydrat k141_19630_1 1288826.MSNKSG1_06553 1.87e-16 80.1 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,465YY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II/IV secretion system protein - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_11986_1 714961.BFZC1_05788 3.63e-32 128.0 COG2199@1|root,COG3706@2|Bacteria,1TSGN@1239|Firmicutes,4HED7@91061|Bacilli,3IX2K@400634|Lysinibacillus 91061|Bacilli T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_9 k141_16134_1 1288826.MSNKSG1_08128 1.34e-126 367.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,465NZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_18955_1 1123400.KB904747_gene552 1.53e-100 308.0 COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,1RQCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Radical SAM - - - - - - - - - - - - B12-binding,DUF4080,Radical_SAM k141_14068_1 1229909.NSED_05375 1.69e-21 90.5 arCOG02703@1|root,arCOG02703@2157|Archaea 2157|Archaea S Methyltransferase type 11 - - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 k141_14068_2 1122194.AUHU01000006_gene431 1.32e-88 262.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,467WP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_14068_4 1267005.KB911263_gene1308 0.000247 45.8 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2UBRG@28211|Alphaproteobacteria,3N7B1@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_3611_2 1236959.BAMT01000010_gene3264 2.97e-61 190.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KMXA@206350|Nitrosomonadales 206350|Nitrosomonadales C NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 - - - - - - - - - - - - Oxidored_q4 k141_17525_1 1249627.D779_0214 1.15e-56 187.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His k141_17525_2 1198232.CYCME_0911 2.99e-08 52.0 COG3242@1|root,COG3242@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2065) yjeT - - ko:K09937 - - - - ko00000 - - - DUF2065 k141_17525_3 1008459.TASI_0767 4.99e-21 90.5 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,3T2ZZ@506|Alcaligenaceae 28216|Betaproteobacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k141_14777_1 1121403.AUCV01000002_gene455 1.49e-39 144.0 29M87@1|root,3085U@2|Bacteria,1RFIW@1224|Proteobacteria,42ZD2@68525|delta/epsilon subdivisions,2WTTF@28221|Deltaproteobacteria,2MMZC@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_20368_2 1177928.TH2_03195 5.17e-91 276.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2TW57@28211|Alphaproteobacteria,2JSI4@204441|Rhodospirillales 204441|Rhodospirillales S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE k141_12667_1 326297.Sama_1803 7.8e-09 57.4 COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,2Q8J9@267890|Shewanellaceae 1236|Gammaproteobacteria S Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase bax - - ko:K03796 - - - - ko00000 - GH73 - Glucosaminidase k141_10582_1 396588.Tgr7_2227 2.7e-18 90.1 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales 135613|Chromatiales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri,YfiO k141_10582_2 1384054.N790_05915 4.61e-105 308.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k141_2904_1 1185766.DL1_10115 4.96e-84 257.0 COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria,2XMM1@285107|Thioclava 28211|Alphaproteobacteria G HAD family hydrolase MA20_05625 - - - - - - - - - - - Hydrolase_6,Hydrolase_like k141_11988_1 1313301.AUGC01000008_gene493 3.02e-85 263.0 2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_21697_2 485918.Cpin_3875 2.04e-41 144.0 2A67E@1|root,30UZZ@2|Bacteria,4NY60@976|Bacteroidetes,1IXF5@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3800) - - - - - - - - - - - - DUF3800 k141_17526_1 396588.Tgr7_1129 6.57e-71 239.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWJ6@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_12668_1 582744.Msip34_2259 1.26e-56 184.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KKPH@206350|Nitrosomonadales 206350|Nitrosomonadales T TIGRFAM phosphate regulon transcriptional regulatory protein PhoB - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_16846_1 1278309.KB907100_gene2093 6.32e-70 220.0 2AAYF@1|root,310BX@2|Bacteria,1RESE@1224|Proteobacteria,1S5GS@1236|Gammaproteobacteria,1XPJG@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16846_2 1278309.KB907100_gene2094 5.7e-196 548.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria,1XHW6@135619|Oceanospirillales 135619|Oceanospirillales M COG0859 ADP-heptose LPS heptosyltransferase waaC - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_16846_3 1278309.KB907100_gene2095 2.07e-200 558.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1XR9S@135619|Oceanospirillales 135619|Oceanospirillales EH Branched-chain amino acid aminotransferase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_2202_1 1131814.JAFO01000001_gene4523 8.5e-31 115.0 2DZRC@1|root,32VGV@2|Bacteria,1N3WQ@1224|Proteobacteria,2UFD2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Cytochrom_C_2 k141_2202_2 1430440.MGMSRv2_4122 1.87e-89 273.0 COG0834@1|root,COG0834@2|Bacteria,1R7DC@1224|Proteobacteria 1224|Proteobacteria ET Periplasmic component of amino acid ABC-type transporter signal transduction system - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_2202_3 395495.Lcho_1464 7.21e-177 535.0 COG0642@1|root,COG0784@1|root,COG1956@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1956@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGMB@28216|Betaproteobacteria,1KPMJ@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Cache domain - - 2.7.13.3 ko:K11527 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1 k141_7087_1 344747.PM8797T_23971 1.58e-60 201.0 COG0389@1|root,COG0389@2|Bacteria,2IZ2I@203682|Planctomycetes 203682|Planctomycetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k141_6382_1 395493.BegalDRAFT_0696 1.3e-78 244.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,460C1@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_19632_1 1001585.MDS_4622 3.56e-24 106.0 COG2199@1|root,COG2203@1|root,COG5002@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria,1YHI5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,dCache_3 k141_16136_2 985665.HPL003_07450 1.39e-41 145.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,26RTI@186822|Paenibacillaceae 91061|Bacilli D Sporulation initiation inhibitor Soj soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_86_1 740709.A10D4_11439 2.15e-68 228.0 COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,2QGBE@267893|Idiomarinaceae 1236|Gammaproteobacteria N SRP54-type protein, GTPase domain flhF - - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 k141_86_2 1121878.AUGL01000022_gene3659 1.08e-46 167.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP k141_3613_1 1300350.DSW25_04440 4.11e-71 222.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2TV6I@28211|Alphaproteobacteria,3ZXQA@60136|Sulfitobacter 28211|Alphaproteobacteria ET Amino acid ABC transporter - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_14779_1 1026882.MAMP_02636 4.69e-50 163.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,460TV@72273|Thiotrichales 72273|Thiotrichales S PFAM L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD k141_4296_1 443152.MDG893_07695 3.51e-262 728.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,46B46@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.44 ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k141_4296_2 443152.MDG893_07690 3.52e-248 686.0 COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,1SQI2@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - - - - - - - - - - Peripla_BP_6 k141_17527_1 1123400.KB904759_gene2055 5.99e-87 274.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,45ZZU@72273|Thiotrichales 72273|Thiotrichales S Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_8486_1 121225.PHUM448870-PA 2.93e-11 63.2 COG2303@1|root,KOG1238@2759|Eukaryota,38UEK@33154|Opisthokonta,3BMXI@33208|Metazoa,3CZU0@33213|Bilateria,41UDX@6656|Arthropoda,3SFUR@50557|Insecta,3ECTT@33342|Paraneoptera 33208|Metazoa E GMC oxidoreductase - GO:0002165,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006629,GO:0007275,GO:0008150,GO:0008152,GO:0008202,GO:0009791,GO:0009987,GO:0010817,GO:0016491,GO:0030312,GO:0032501,GO:0032502,GO:0034754,GO:0042180,GO:0042445,GO:0042600,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045455,GO:0048856,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360 1.1.3.49,1.1.5.9 ko:K00115,ko:K21270 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R00305 RC00066 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_8486_2 314271.RB2654_05612 2.76e-34 128.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - ko:K07003 - - - - ko00000 - - - MMPL,cNMP_binding k141_12669_1 90813.JQMT01000001_gene258 4.73e-101 301.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,4609M@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_7088_1 1288826.MSNKSG1_05898 9.34e-148 436.0 COG0369@1|root,COG3182@1|root,COG0369@2|Bacteria,COG3182@2|Bacteria,1MWYV@1224|Proteobacteria,1RY05@1236|Gammaproteobacteria,465H6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Flavodoxin cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,FAD_binding_6,Flavodoxin_1,NAD_binding_1,PepSY_TM k141_18956_3 1196324.A374_16914 1.81e-53 183.0 COG0846@1|root,COG0846@2|Bacteria,1VF69@1239|Firmicutes,4HXHS@91061|Bacilli 91061|Bacilli K SIR2-like domain - - - - - - - - - - - - SIR2_2 k141_20369_2 1122614.JHZF01000011_gene710 4.06e-149 423.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,2TR8U@28211|Alphaproteobacteria,2PDIY@252301|Oceanicola 28211|Alphaproteobacteria K DeoR C terminal sensor domain glpR - - ko:K02444 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k141_6383_1 367336.OM2255_03800 1.56e-107 335.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_19633_1 706587.Desti_5260 8.72e-104 310.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MQ8F@213462|Syntrophobacterales 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_11989_2 768671.ThimaDRAFT_0894 9.9e-46 149.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1WYVV@135613|Chromatiales 135613|Chromatiales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_11989_3 395493.BegalDRAFT_0930 7.29e-106 315.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales 72273|Thiotrichales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_2203_2 1198452.Jab_2c32510 1.6e-72 238.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,473HW@75682|Oxalobacteraceae 28216|Betaproteobacteria EGP Major Facilitator Superfamily bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_16137_1 1232683.ADIMK_0258 2.59e-56 190.0 COG4447@1|root,COG4447@2|Bacteria,1R5ZV@1224|Proteobacteria,1S0FG@1236|Gammaproteobacteria,466PS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Photosynthesis system II assembly factor YCF48 - - - - - - - - - - - - PSII_BNR k141_9858_1 349124.Hhal_2265 8.3e-25 99.4 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1WZ5M@135613|Chromatiales 135613|Chromatiales K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components rfaH - - ko:K05785 - - - - ko00000,ko03000 - - - NusG k141_9858_2 1235803.C825_04452 5.58e-06 47.8 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,2FNA5@200643|Bacteroidia,22W0D@171551|Porphyromonadaceae 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k141_1499_1 1288826.MSNKSG1_17650 3.02e-281 768.0 2DR20@1|root,339U3@2|Bacteria,1NI48@1224|Proteobacteria,1SGK9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1499_2 1288826.MSNKSG1_17655 7.99e-138 396.0 2F1ZF@1|root,33UYR@2|Bacteria,1NVFQ@1224|Proteobacteria,1SQGG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21698_2 1232683.ADIMK_2984 2.68e-45 150.0 COG0346@1|root,COG0346@2|Bacteria,1PW6M@1224|Proteobacteria,1RUE3@1236|Gammaproteobacteria,46C9V@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_21698_3 358681.BBR47_30450 8.88e-36 127.0 COG1673@1|root,COG1673@2|Bacteria,1VAXR@1239|Firmicutes,4HKYH@91061|Bacilli,26XRM@186822|Paenibacillaceae 91061|Bacilli S Belongs to the UPF0310 family ydcG - - - - - - - - - - - EVE k141_20370_1 2340.JV46_16680 4.05e-55 178.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G HAD-hyrolase-like gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 HAD_2 k141_3614_1 1506583.JQJY01000004_gene2623 1.09e-89 288.0 COG0277@1|root,COG0277@2|Bacteria,4PCSU@976|Bacteroidetes,1IF9Z@117743|Flavobacteriia,2NYPA@237|Flavobacterium 976|Bacteroidetes C FAD binding domain - - - - - - - - - - - - FAD_binding_4 k141_12670_1 118168.MC7420_8061 1.33e-10 67.8 COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3,PAS_4 k141_11310_1 1288826.MSNKSG1_17431 0.0 1005.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,464HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_14234_1 1288826.MSNKSG1_05883 3.64e-58 184.0 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1SYUC@1236|Gammaproteobacteria,46ABI@72275|Alteromonadaceae 1236|Gammaproteobacteria K response regulator - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_14234_2 1288826.MSNKSG1_05878 6.57e-282 775.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase ygiY - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_14234_3 1288826.MSNKSG1_05873 0.0 935.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1S48Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_14234_4 1288826.MSNKSG1_05868 2.12e-68 207.0 COG1993@1|root,COG1993@2|Bacteria,1MZ79@1224|Proteobacteria,1T0G0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized ACR, COG1993 - - - - - - - - - - - - DUF190 k141_14234_5 1288826.MSNKSG1_05863 1.62e-86 254.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S9GR@1236|Gammaproteobacteria,46CT5@72275|Alteromonadaceae 1236|Gammaproteobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_14234_7 1288826.MSNKSG1_05853 3.14e-92 270.0 COG1585@1|root,COG1585@2|Bacteria,1NQ8Q@1224|Proteobacteria,1SPG6@1236|Gammaproteobacteria 1236|Gammaproteobacteria OU NfeD-like C-terminal, partner-binding - - - ko:K07340 - - - - ko00000 - - - NfeD k141_14234_8 1288826.MSNKSG1_05848 6.26e-162 461.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,465XW@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Band_7,Band_7_C k141_14234_10 1288826.MSNKSG1_05843 3.34e-209 578.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,466ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial transcription activator, effector binding domain - - - ko:K07506,ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 k141_18423_1 388401.RB2150_11266 9.58e-216 610.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3ZGR9@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate betA - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_19164_1 1121459.AQXE01000003_gene1143 2.77e-75 243.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,42N6Q@68525|delta/epsilon subdivisions,2WJVG@28221|Deltaproteobacteria,2M7XM@213115|Desulfovibrionales 28221|Deltaproteobacteria P Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K02168,ko:K03451 - - - - ko00000,ko02000 2.A.15,2.A.15.1.3,2.A.15.1.4 - - BCCT k141_17022_1 431943.CKL_2357 1.05e-126 391.0 COG0318@1|root,COG0318@2|Bacteria,1UZQF@1239|Firmicutes,25ECZ@186801|Clostridia,36DGR@31979|Clostridiaceae 186801|Clostridia IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C,KR,NAD_binding_4,PP-binding k141_11469_2 1122604.JONR01000003_gene1498 1.84e-65 223.0 28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,1S04D@1236|Gammaproteobacteria,1X51D@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k141_11469_3 690850.Desaf_1692 6.27e-179 518.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2M8GG@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM Sodium sulphate symporter sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp k141_11469_4 314278.NB231_08705 4.01e-30 112.0 COG1999@1|root,COG1999@2|Bacteria,1RKIP@1224|Proteobacteria,1S62T@1236|Gammaproteobacteria,1X2FG@135613|Chromatiales 135613|Chromatiales S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_10789_1 94122.Shewana3_0022 3.9e-100 308.0 COG2199@1|root,COG2199@2|Bacteria,1NYG9@1224|Proteobacteria,1RV5M@1236|Gammaproteobacteria,2QD9V@267890|Shewanellaceae 1236|Gammaproteobacteria T Protoglobin - - - - - - - - - - - - GGDEF,Protoglobin k141_14953_1 1123368.AUIS01000023_gene933 2.63e-117 374.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 k141_21277_1 1123360.thalar_03375 5.86e-104 305.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria 28211|Alphaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 k141_21952_1 314345.SPV1_08281 9.65e-250 714.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria 1224|Proteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k141_16318_1 1318628.MARLIPOL_02145 1.26e-141 409.0 COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria,466H7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family oprF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OprF,TSP_3 k141_16318_2 1318628.MARLIPOL_02140 5.75e-129 390.0 COG3391@1|root,COG3391@2|Bacteria,1QX6H@1224|Proteobacteria,1T3DD@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Thrombospondin type 3 repeat - - - - - - - - - - - - TSP_3 k141_16318_4 1288826.MSNKSG1_09578 5.43e-293 802.0 COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,1RP1Y@1236|Gammaproteobacteria,4664N@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_16318_5 1288826.MSNKSG1_09573 1.23e-190 530.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,466GS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ - 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ k141_16318_6 1288826.MSNKSG1_09568 9.23e-286 782.0 28PP2@1|root,2ZCBJ@2|Bacteria,1RCCZ@1224|Proteobacteria,1S3QI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16318_7 1288826.MSNKSG1_09563 5.36e-68 213.0 COG0668@1|root,COG0668@2|Bacteria,1QATN@1224|Proteobacteria,1RRIZ@1236|Gammaproteobacteria,468QQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel protein MscS - - - - - - - - - - - - MS_channel k141_2411_1 391626.OAN307_c28650 8.73e-25 105.0 COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Protein of unknown function MA20_30770 - - - - - - - - - - - AsmA_2,DUF3971 k141_2411_2 1288298.rosmuc_03183 2.78e-33 125.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria,46P11@74030|Roseovarius 28211|Alphaproteobacteria H Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_5909_1 1278309.KB907099_gene2652 1.51e-82 256.0 COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RZJ1@1236|Gammaproteobacteria,1XIDA@135619|Oceanospirillales 135619|Oceanospirillales C Quinohemoprotein amine dehydrogenase - - - - - - - - - - - - Fer4_12,Radical_SAM k141_5909_2 1278309.KB907099_gene2653 4.49e-78 231.0 2BBG1@1|root,324ZB@2|Bacteria,1RHTK@1224|Proteobacteria,1S6WW@1236|Gammaproteobacteria,1XKBI@135619|Oceanospirillales 135619|Oceanospirillales S Quinohemoprotein amine dehydrogenase, gamma subunit - - - - - - - - - - - - QH-AmDH_gamma k141_5909_3 1278309.KB907099_gene2654 1.12e-244 675.0 COG3391@1|root,COG3391@2|Bacteria,1P6I0@1224|Proteobacteria,1S07W@1236|Gammaproteobacteria,1XJ1U@135619|Oceanospirillales 135619|Oceanospirillales S Quinohemoprotein amine dehydrogenase - - - - - - - - - - - - - k141_5909_4 1278309.KB907099_gene2655 4.1e-19 86.3 COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,1S1JM@1236|Gammaproteobacteria,1XI18@135619|Oceanospirillales 135619|Oceanospirillales M Alginate export - - - - - - - - - - - - Alginate_exp k141_8055_1 1288826.MSNKSG1_13732 1.57e-100 302.0 COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,1T1TS@1236|Gammaproteobacteria,468B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_2412_1 1232683.ADIMK_0283 2.05e-52 176.0 COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,469VP@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein involved in benzoate metabolism benE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE k141_13554_1 1121104.AQXH01000002_gene653 1.63e-106 315.0 COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1IQ8U@117747|Sphingobacteriia 976|Bacteroidetes E PFAM glutamine synthetase catalytic region glnII - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N k141_16319_1 666509.RCA23_c12020 1.74e-105 310.0 COG0559@1|root,COG0559@2|Bacteria,1R63E@1224|Proteobacteria,2U465@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_16319_2 666509.RCA23_c12030 1.03e-17 80.9 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component MA20_38130 - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k141_20585_1 1288826.MSNKSG1_16161 1.05e-210 592.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,467GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase qseC - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_20585_2 1288826.MSNKSG1_16166 1.06e-142 404.0 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1SYUC@1236|Gammaproteobacteria,466DP@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483,ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_20585_3 1288826.MSNKSG1_16171 1.39e-61 189.0 COG5591@1|root,COG5591@2|Bacteria,1N7YT@1224|Proteobacteria,1SE3Z@1236|Gammaproteobacteria,468TS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 k141_20585_4 1288826.MSNKSG1_16176 4e-131 371.0 COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,1S9SA@1236|Gammaproteobacteria,46B0K@72275|Alteromonadaceae 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_20585_5 1288826.MSNKSG1_16181 1.09e-205 578.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - - - - - - - - - - - PMT,PMT_2 k141_8687_1 1288826.MSNKSG1_16566 7.21e-70 221.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,4660V@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1566 Multidrug resistance efflux pump yiaV - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_8687_2 1288826.MSNKSG1_16571 4.75e-21 85.9 COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1S26B@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcription regulator that can specifically activate or repress expression of target genes slyA GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0043254,GO:0044087,GO:0044089,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141 - ko:K06075 - - - - ko00000,ko03000 - - - MarR,MarR_2 k141_18433_1 367336.OM2255_06505 5.26e-06 47.8 COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type tungstate transport system, periplasmic component MA20_34300 - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 k141_18433_2 1342301.JASD01000008_gene2979 2.55e-21 94.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,3ZV6F@60136|Sulfitobacter 28211|Alphaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_1016_1 977880.RALTA_A1499 1.37e-21 90.9 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,1K1E9@119060|Burkholderiaceae 28216|Betaproteobacteria L TIGRFAM hydrolase, TatD family ycfH - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_1016_2 391615.ABSJ01000017_gene1670 3.16e-28 105.0 COG2940@1|root,COG2940@2|Bacteria,1NEQQ@1224|Proteobacteria,1SFED@1236|Gammaproteobacteria,1JBD2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET k141_1016_3 523791.Kkor_2560 8.45e-96 287.0 COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,1XJMM@135619|Oceanospirillales 135619|Oceanospirillales P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - - k141_1016_4 1385515.N791_10135 2.25e-25 95.9 COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,1X8WH@135614|Xanthomonadales 135614|Xanthomonadales S Cation transport regulator chaB - - ko:K06197 - - - - ko00000 - - - ChaB k141_1016_5 323261.Noc_0824 2.86e-46 153.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,1WYMN@135613|Chromatiales 135613|Chromatiales I PFAM thioesterase superfamily - - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT k141_1016_6 765912.Thimo_2040 3.1e-162 477.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding k141_10049_1 1255043.TVNIR_3001 4.77e-53 180.0 2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria,1SBQY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19816_2 1042375.AFPL01000052_gene407 5.58e-69 244.0 COG0840@1|root,COG0840@2|Bacteria,1R9DJ@1224|Proteobacteria,1RYXS@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein ctpL - - - - - - - - - - - MCPsignal k141_19816_3 1278309.KB907109_gene3225 2.05e-257 707.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XHDH@135619|Oceanospirillales 135619|Oceanospirillales F carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_19816_4 1278309.KB907109_gene3226 0.0 1989.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XHKH@135619|Oceanospirillales 135619|Oceanospirillales F Carbamoyl-phosphate synthetase ammonia chain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_19816_5 1278309.KB907109_gene3227 3.56e-91 268.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1XJHQ@135619|Oceanospirillales 135619|Oceanospirillales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_19816_6 1278309.KB907109_gene3228 1.64e-56 176.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1XKKN@135619|Oceanospirillales 135619|Oceanospirillales J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY k141_19816_7 1278309.KB907109_gene3229 9.15e-41 139.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1XHHV@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_19185_1 1323663.AROI01000009_gene3481 1.6e-06 52.8 COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - PSII_BNR k141_19185_2 1278309.KB907099_gene2562 9.67e-128 384.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,1XHP8@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_19185_3 1149133.ppKF707_5791 2.24e-07 59.3 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1S4PH@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_10808_1 697282.Mettu_0378 7.05e-158 458.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria,1XDQW@135618|Methylococcales 135618|Methylococcales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit - - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_10808_2 1121403.AUCV01000038_gene4228 6.48e-14 73.6 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria 1224|Proteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF_2 - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP k141_21954_1 1120956.JHZK01000004_gene1394 9.23e-108 323.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,1JN20@119043|Rhodobiaceae 28211|Alphaproteobacteria E Aminotransferase class-III bioA - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_15661_1 1232683.ADIMK_0256 2.97e-65 214.0 COG3103@1|root,COG3103@2|Bacteria,1QXFZ@1224|Proteobacteria,1RPAR@1236|Gammaproteobacteria,465YC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Sh3 type 3 domain protein - - - - - - - - - - - - DUF1302 k141_15661_2 1122599.AUGR01000007_gene1182 4.75e-80 260.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XITB@135619|Oceanospirillales 135619|Oceanospirillales S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_9341_1 1116375.VEJY3_23921 5.53e-24 101.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XVHW@135623|Vibrionales 135623|Vibrionales E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_9341_2 1123401.JHYQ01000002_gene2652 1.45e-33 125.0 COG3751@1|root,COG3751@2|Bacteria,1NBA8@1224|Proteobacteria,1SKR2@1236|Gammaproteobacteria 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_4 k141_10050_2 637905.SVI_2999 4.07e-21 90.5 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,2QATH@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_0281 THF_DHG_CYH,THF_DHG_CYH_C k141_331_2 1278309.KB907103_gene1010 6.12e-79 236.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1XKER@135619|Oceanospirillales 135619|Oceanospirillales U Biopolymer transport protein tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_331_3 1278309.KB907103_gene1011 1.5e-58 197.0 COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria,1S6QG@1236|Gammaproteobacteria,1XRZZ@135619|Oceanospirillales 135619|Oceanospirillales M TonB C terminal - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_331_4 1278309.KB907103_gene1012 6.36e-204 576.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XITW@135619|Oceanospirillales 135619|Oceanospirillales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_331_5 1278309.KB907103_gene1013 1.09e-93 276.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1XK2R@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_331_6 1278309.KB907103_gene1014 3.77e-102 305.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1XK5H@135619|Oceanospirillales 135619|Oceanospirillales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_331_7 1278309.KB907103_gene1015 6.85e-49 161.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XHZB@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k141_1017_1 292415.Tbd_2491 1.31e-21 95.1 COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria 28216|Betaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD k141_14956_1 225937.HP15_2056 9.17e-103 298.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,466YU@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1522 Transcriptional regulators lrp_2 - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_6554_3 1121948.AUAC01000004_gene161 7.17e-76 253.0 COG2131@1|root,COG2131@2|Bacteria,1PMV0@1224|Proteobacteria,2U2JZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria F PFAM CMP dCMP deaminase zinc-binding - - - - - - - - - - - - dCMP_cyt_deam_1 k141_3150_1 768066.HELO_2200 1.05e-28 115.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XIEE@135619|Oceanospirillales 135619|Oceanospirillales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k141_20586_1 1278309.KB907101_gene598 6.14e-92 272.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XJ8Q@135619|Oceanospirillales 135619|Oceanospirillales T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_4536_1 396588.Tgr7_1923 3.41e-82 257.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1WVUM@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_21955_2 1125971.ASJB01000062_gene4438 1.76e-26 107.0 COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4DZTG@85010|Pseudonocardiales 201174|Actinobacteria S Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - DLH,Pribosyltran k141_18434_1 644107.SL1157_1084 2.27e-143 414.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,4NAQK@97050|Ruegeria 28211|Alphaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_21280_1 1163617.SCD_n00507 6.78e-07 50.4 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria 28216|Betaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC - 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - - Chor_lyase k141_18568_4 1278309.KB907099_gene2979 3.97e-294 806.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 k141_18568_5 1278309.KB907099_gene2978 7.03e-123 356.0 COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,1XIPN@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21699 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_17915_1 1123514.KB905899_gene888 5e-29 115.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,460RP@72273|Thiotrichales 72273|Thiotrichales EGP Drug resistance transporter Bcr CflA subfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_17915_2 349521.HCH_06834 6.41e-99 306.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XHYA@135619|Oceanospirillales 135619|Oceanospirillales K containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_3287_1 1278309.KB907099_gene2702 1.23e-115 351.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XHFF@135619|Oceanospirillales 135619|Oceanospirillales T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_3287_2 1122599.AUGR01000021_gene3208 4.57e-17 79.3 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,1XHA6@135619|Oceanospirillales 135619|Oceanospirillales C Ferredoxin - - - ko:K21832 - - - - ko00000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_11606_1 1190606.AJYG01000089_gene4722 8.03e-11 64.7 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XTM7@135623|Vibrionales 135623|Vibrionales N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_11606_2 335283.Neut_2061 2.1e-30 117.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,37217@32003|Nitrosomonadales 28216|Betaproteobacteria N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_12350_1 1231392.OCGS_2445 1.18e-06 47.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2UC01@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 k141_12350_2 367336.OM2255_07855 1.38e-78 234.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2U6ZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 k141_12350_3 367336.OM2255_07850 2.25e-102 298.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k141_12350_4 1469613.JT55_13760 7.98e-66 201.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria,3FDBN@34008|Rhodovulum 28211|Alphaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k141_12350_5 999611.KI421504_gene1112 6.13e-35 123.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria,280H6@191028|Leisingera 28211|Alphaproteobacteria J Ribosomal protein S5, C-terminal domain rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C k141_13057_2 1049564.TevJSym_ab02040 2.44e-84 258.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,1J6J1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised protein family UPF0066 yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - - - - - - - - - - UPF0066 k141_1862_1 367336.OM2255_07300 2.5e-61 206.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, permease component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_2528_1 95619.PM1_0221855 4.49e-70 235.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_485_1 1288826.MSNKSG1_06123 9.06e-122 353.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RN0N@1236|Gammaproteobacteria,4663H@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 cioB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_485_2 1288826.MSNKSG1_06128 6.67e-39 142.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,465RH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_4674_1 1288826.MSNKSG1_02951 4.09e-73 226.0 2EGPT@1|root,33AFY@2|Bacteria,1NGQG@1224|Proteobacteria,1SHME@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4674_2 1288826.MSNKSG1_02946 2.88e-300 827.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,464AE@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria rmuC GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K09760 - - - - ko00000 - - - RmuC k141_17916_1 1095769.CAHF01000003_gene1053 4.82e-43 159.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,472EW@75682|Oxalobacteraceae 28216|Betaproteobacteria O ResB-like family resB - - ko:K07399 - - - - ko00000 - - - ResB k141_5361_1 1278309.KB907099_gene2962 4.99e-140 407.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHZD@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamine synthetase family - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_5361_2 1278309.KB907099_gene2963 1.95e-89 271.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XHQ6@135619|Oceanospirillales 135619|Oceanospirillales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069,ko:K11073 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 k141_7442_1 314345.SPV1_05597 5.15e-29 114.0 COG0524@1|root,COG0524@2|Bacteria 2|Bacteria G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway frk - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_7442_2 317025.Tcr_1797 8.76e-59 199.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZPC@72273|Thiotrichales 72273|Thiotrichales G PFAM alpha amylase, catalytic - - 2.4.1.4 ko:K05341 ko00500,map00500 - R01823 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k141_10209_1 1158762.KB898042_gene987 1.12e-09 55.8 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1TJD2@1236|Gammaproteobacteria,1WYEP@135613|Chromatiales 135613|Chromatiales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF k141_10209_2 631362.Thi970DRAFT_03685 1.63e-74 240.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1WW9A@135613|Chromatiales 135613|Chromatiales G PFAM carbohydrate kinase - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_3288_1 351348.Maqu_3396 2.33e-17 81.3 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1PQPU@1224|Proteobacteria,1RYEZ@1236|Gammaproteobacteria,464T5@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0835 Chemotaxis signal transduction protein cheV3 - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_3288_2 631362.Thi970DRAFT_00922 1.56e-40 146.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1WVUM@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_13734_1 762982.HMPREF9442_01435 3.99e-13 75.5 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y k141_13734_3 1122599.AUGR01000025_gene1469 1.35e-30 114.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_15071_1 1001585.MDS_4536 9.8e-138 402.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1YCY9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB2 - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_15071_2 1288826.MSNKSG1_15467 4.99e-170 476.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,464YT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria HA62_17960 - - - - - - - - - - - Metallophos,Metallophos_2 k141_14350_1 1279009.ADICEAN_04115 3.62e-74 228.0 293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,47PUM@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldD gldD - - - - - - - - - - - - k141_8776_1 754477.Q7C_2270 3.65e-98 296.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,460K7@72273|Thiotrichales 72273|Thiotrichales S DNA polymerase alpha chain like domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP k141_12351_1 349102.Rsph17025_2952 1.7e-57 202.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,1FBFQ@1060|Rhodobacter 28211|Alphaproteobacteria L PD-(D/E)XK nuclease superfamily addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_5997_1 388401.RB2150_14416 8.89e-144 419.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,3ZH0C@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria L COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member recD2 - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k141_9451_1 414684.RC1_2267 2.76e-25 103.0 COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,2TS26@28211|Alphaproteobacteria,2JS64@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC k141_9451_2 638302.HMPREF0908_1524 1.44e-28 108.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes 1239|Firmicutes F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 k141_19322_1 396588.Tgr7_0950 2.69e-114 346.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales 135613|Chromatiales P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_10210_2 94122.Shewana3_0022 2.39e-47 166.0 COG2199@1|root,COG2199@2|Bacteria,1NYG9@1224|Proteobacteria,1RV5M@1236|Gammaproteobacteria,2QD9V@267890|Shewanellaceae 1236|Gammaproteobacteria T Protoglobin - - - - - - - - - - - - GGDEF,Protoglobin k141_1197_1 589865.DaAHT2_2627 3.49e-47 162.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,42ZQU@68525|delta/epsilon subdivisions,2WUSE@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM MscS Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_1197_3 1123368.AUIS01000007_gene2818 6.37e-29 108.0 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C k141_15072_1 1248232.BANQ01000080_gene2498 2.52e-22 97.8 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XSDH@135623|Vibrionales 135623|Vibrionales I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_15846_4 1042377.AFPJ01000030_gene477 1.78e-83 253.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,466DA@72275|Alteromonadaceae 1236|Gammaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX k141_15846_5 1198232.CYCME_0585 3.43e-19 86.7 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,46103@72273|Thiotrichales 72273|Thiotrichales S protein conserved in bacteria - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_17934_1 272123.Anacy_2164 6.92e-47 157.0 28W7P@1|root,2ZI89@2|Bacteria,1G6ZY@1117|Cyanobacteria,1HSAN@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - k141_17934_2 998674.ATTE01000001_gene3030 6.51e-80 245.0 COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,1S125@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - AbiEii k141_12368_2 566466.NOR53_289 9.81e-25 93.6 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1JB5J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L30p/L7e rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 k141_1209_1 1266914.ATUK01000011_gene2269 1.36e-06 48.9 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1WWJX@135613|Chromatiales 135613|Chromatiales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_1209_2 637905.SVI_3111 6.64e-52 173.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,2QAQH@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM OmpW family protein ompW GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K07275 - - - - ko00000 - - - OmpW k141_1209_3 1038922.PflQ2_0394 7.88e-69 220.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1YM23@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM k141_5379_1 1278309.KB907108_gene1602 8.96e-227 627.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XR7Y@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase FAD-binding domain - - - - - - - - - - - - FAD_binding_6,Fer2,NAD_binding_1 k141_5379_2 1278309.KB907108_gene1603 7.59e-70 211.0 2DGRK@1|root,32U7S@2|Bacteria,1N22H@1224|Proteobacteria,1S6UD@1236|Gammaproteobacteria,1XKR7@135619|Oceanospirillales 135619|Oceanospirillales S Phenol hydroxylase conserved region - - - - - - - - - - - - Phenol_monoox k141_18587_1 675814.VIC_002628 1.05e-58 186.0 COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1RP41@1236|Gammaproteobacteria,1Y2G8@135623|Vibrionales 135623|Vibrionales F Shikimate kinase idnK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - SKI k141_10953_1 748280.NH8B_3097 1.82e-08 55.8 2E5SP@1|root,330H2@2|Bacteria,1NDBY@1224|Proteobacteria,2VXDV@28216|Betaproteobacteria 28216|Betaproteobacteria S YMGG-like Gly-zipper - - - - - - - - - - - - Gly-zipper_OmpA,Gly-zipper_YMGG k141_10953_2 1205908.AKXW01000086_gene2082 1.47e-17 83.2 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales 135623|Vibrionales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC2 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_2548_1 765911.Thivi_0551 8.41e-97 296.0 COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales 135613|Chromatiales C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_17,Fer4_8 k141_2548_2 292415.Tbd_2479 3.89e-98 291.0 COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria 28216|Betaproteobacteria C Nitrate reductase gamma subunit - - - - - - - - - - - - Nitrate_red_gam k141_6691_1 1163408.UU9_07688 3.33e-88 265.0 COG2854@1|root,COG2854@2|Bacteria,1R4I3@1224|Proteobacteria,1RY1E@1236|Gammaproteobacteria,1XBZ7@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents auxiliary component - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_4689_1 765912.Thimo_1742 1.93e-81 252.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1X29Z@135613|Chromatiales 135613|Chromatiales C PFAM Alcohol dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 k141_17187_1 1168065.DOK_15074 7.57e-122 364.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,1J4US@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_17187_2 1122197.ATWI01000008_gene2819 2.74e-138 409.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,46625@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_6007_1 1122599.AUGR01000030_gene498 1.54e-167 471.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,1XHQZ@135619|Oceanospirillales 135619|Oceanospirillales K competence protein - - - - - - - - - - - - - k141_6007_2 1278309.KB907106_gene1217 2.39e-165 467.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1XHBR@135619|Oceanospirillales 135619|Oceanospirillales S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N k141_6007_3 1278309.KB907106_gene1218 3.23e-13 67.8 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XI8X@135619|Oceanospirillales 135619|Oceanospirillales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_3926_1 398580.Dshi_1568 0.000211 42.7 COG0168@1|root,COG0168@2|Bacteria,1MWV4@1224|Proteobacteria,2TQP5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0168 Trk-type K transport systems, membrane components trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_3926_2 985054.JQEZ01000005_gene345 9.73e-44 142.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,4NCGC@97050|Ruegeria 28211|Alphaproteobacteria J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq k141_3926_3 1294273.roselon_02898 5.53e-19 87.4 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_3306_1 666509.RCA23_c30040 6.36e-64 213.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_3306_2 1041146.ATZB01000014_gene1841 6.09e-105 321.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,4BAYM@82115|Rhizobiaceae 28211|Alphaproteobacteria G Malonyl-CoA decarboxylase matA - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_10228_1 1122604.JONR01000001_gene1679 9.36e-45 169.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1X4ST@135614|Xanthomonadales 135614|Xanthomonadales S Large extracellular alpha-helical protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1 k141_9465_1 105559.Nwat_0110 1.37e-121 360.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1WWIR@135613|Chromatiales 135613|Chromatiales H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_16490_1 1288826.MSNKSG1_13722 6.63e-59 191.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RN38@1236|Gammaproteobacteria,46BGS@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 phbC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k141_16490_2 1288826.MSNKSG1_13727 1.14e-154 434.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria,466A6@72275|Alteromonadaceae 1236|Gammaproteobacteria S haloacid dehalogenase hadL - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_16490_3 1288826.MSNKSG1_13732 2.83e-47 162.0 COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,1T1TS@1236|Gammaproteobacteria,468B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_6008_2 857087.Metme_0534 8.2e-61 191.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XF23@135618|Methylococcales 135618|Methylococcales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_17188_1 1288826.MSNKSG1_08593 9.03e-103 308.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,1RPSF@1236|Gammaproteobacteria,46D4F@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG0477 Permeases of the major facilitator superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 k141_19961_2 1348114.OM33_12830 4.85e-115 335.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,2PZJ1@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k141_21418_1 1304885.AUEY01000032_gene2024 2.6e-33 134.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MJZH@213118|Desulfobacterales 28221|Deltaproteobacteria T CHASE2 - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_21418_2 1121035.AUCH01000022_gene3197 8.17e-80 259.0 COG2206@1|root,COG2206@2|Bacteria,1R3VR@1224|Proteobacteria,2VMY5@28216|Betaproteobacteria,2KVPZ@206389|Rhodocyclales 206389|Rhodocyclales T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD_5 k141_21418_3 1121267.JHZL01000039_gene460 2.49e-08 50.4 2AICC@1|root,318TJ@2|Bacteria,1Q0XM@1224|Proteobacteria,431XH@68525|delta/epsilon subdivisions,2YSDI@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria - - - - - - - - - - - - - - - k141_8201_1 1123518.ARWI01000001_gene227 5.52e-184 518.0 COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria 1224|Proteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_8201_2 270374.MELB17_01100 9.86e-38 132.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,468A7@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein-S-isoprenylcysteine methyltransferase - - - - - - - - - - - - PEMT k141_22078_1 1232683.ADIMK_3884 4.92e-153 436.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1T04U@1236|Gammaproteobacteria,469W1@72275|Alteromonadaceae 1236|Gammaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall k141_22078_2 1535422.ND16A_0786 4.28e-75 234.0 COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,1RRJE@1236|Gammaproteobacteria,2Q5XW@267889|Colwelliaceae 1236|Gammaproteobacteria E Putative serine dehydratase domain - - 4.1.2.42,4.1.3.41 ko:K18425,ko:K19967 - - - - ko00000,ko01000 - - - Ala_racemase_N,D-ser_dehydrat k141_11628_1 870187.Thini_4460 1.1e-59 193.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales 72273|Thiotrichales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_14357_1 1123401.JHYQ01000003_gene2120 8.39e-43 158.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZNC@72273|Thiotrichales 72273|Thiotrichales P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_18589_1 396588.Tgr7_0833 1.03e-81 252.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_18589_2 1149133.ppKF707_0412 4.08e-06 47.8 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1YGT6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_11094_1 1121035.AUCH01000002_gene1496 2.23e-08 53.1 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,2KWY2@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 k141_11094_2 1157708.KB907455_gene3209 2.06e-18 83.2 COG5331@1|root,COG5331@2|Bacteria,1Q52X@1224|Proteobacteria,2VY63@28216|Betaproteobacteria 28216|Betaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_12533_1 1300345.LF41_2553 7.16e-29 110.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X508@135614|Xanthomonadales 135614|Xanthomonadales Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_12533_2 95619.PM1_0226035 8.04e-69 216.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 k141_12533_3 697282.Mettu_1203 2.28e-18 80.5 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria,1XFBV@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - k141_11112_1 1288826.MSNKSG1_18150 8.54e-217 601.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,465ZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0438 Glycosyltransferase waaG - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_11112_2 1288826.MSNKSG1_18145 1.76e-217 603.0 COG0438@1|root,COG0438@2|Bacteria,1RKCN@1224|Proteobacteria,1S4CE@1236|Gammaproteobacteria,46BAR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k141_11112_3 1288826.MSNKSG1_18140 1.26e-183 512.0 COG0463@1|root,COG0463@2|Bacteria,1NKC0@1224|Proteobacteria,1RSJ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_11112_4 1288826.MSNKSG1_18135 0.0 931.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,4644C@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the mannose-6-phosphate isomerase type 2 family cpsB GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2191,iEC042_1314.EC042_2286,iECIAI1_1343.ECIAI1_2124,iECO26_1355.ECO26_2960,iECSE_1348.ECSE_2323,iECW_1372.ECW_m2206,iEKO11_1354.EKO11_1746,iEcE24377_1341.EcE24377A_2342,iLF82_1304.LF82_0345,iNRG857_1313.NRG857_10420,iWFL_1372.ECW_m2206 MannoseP_isomer,NTP_transferase k141_11112_5 1288826.MSNKSG1_18130 1.65e-121 352.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,466K6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_11724_1 1278309.KB907100_gene2336 1.13e-209 588.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1XI65@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_11724_2 1278309.KB907100_gene2335 1.24e-150 427.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1XIX6@135619|Oceanospirillales 135619|Oceanospirillales E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ - - ko:K06203 - - - - ko00000 - - - EI24 k141_11724_4 1278309.KB907100_gene2333 4.44e-124 360.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RV93@1236|Gammaproteobacteria,1XR2Y@135619|Oceanospirillales 135619|Oceanospirillales C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 k141_22226_1 207954.MED92_03383 4.15e-259 743.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1XNNB@135619|Oceanospirillales 135619|Oceanospirillales O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_22226_2 522306.CAP2UW1_0733 2.85e-25 96.3 COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria 28216|Betaproteobacteria O Hydrogenase assembly chaperone hypC hupF hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC k141_22226_3 207954.MED92_03393 2.33e-225 627.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1XNW0@135619|Oceanospirillales 135619|Oceanospirillales O Hydrogenase formation hypA family - - - ko:K04654 - - - - ko00000 - - - HypD k141_22226_4 207954.MED92_03398 1.8e-57 187.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1XNMZ@135619|Oceanospirillales 135619|Oceanospirillales O Hydrogenase expression formation protein HypE - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C k141_12534_1 329726.AM1_3046 0.0009 43.1 COG2199@1|root,COG2199@2|Bacteria,1GQW9@1117|Cyanobacteria 1117|Cyanobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_12534_2 572480.Arnit_3144 6.77e-44 148.0 COG2860@1|root,COG2860@2|Bacteria,1RIEK@1224|Proteobacteria,43B6S@68525|delta/epsilon subdivisions,2YT69@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 k141_6792_1 1396858.Q666_02285 2.18e-76 239.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,469BR@72275|Alteromonadaceae 1236|Gammaproteobacteria I Thiolase, C-terminal domain thlA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_6792_2 1085623.GNIT_0102 1.96e-181 516.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPGB@1236|Gammaproteobacteria,464X4@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases hcaD - 1.3.8.8 ko:K00255 ko00071,ko01100,ko01212,ko03320,map00071,map01100,map01212,map03320 M00087 R01279,R03777,R03857,R03990,R04751,R04754 RC00052 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_6792_3 861360.AARI_03660 3.71e-85 261.0 COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,1W8HY@1268|Micrococcaceae 201174|Actinobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_6792_4 1122599.AUGR01000005_gene1828 3.29e-156 447.0 COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,1RQ8P@1236|Gammaproteobacteria,1XIIR@135619|Oceanospirillales 135619|Oceanospirillales K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_6792_5 1122599.AUGR01000005_gene1830 2.42e-141 416.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XI7A@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_20791_1 56110.Oscil6304_1218 1.54e-78 268.0 COG0642@1|root,COG3452@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - ko:K11959,ko:K19694 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko01001,ko02000,ko02022 3.A.1.4.4,3.A.1.4.5 - - CHASE,EAL,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_15178_1 398580.Dshi_1139 8.06e-140 407.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Modulator of DNA gyrase tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_6163_1 472759.Nhal_2479 5.32e-86 276.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WXWN@135613|Chromatiales 135613|Chromatiales I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_9614_1 292415.Tbd_2116 1.18e-51 183.0 COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,2W1FP@28216|Betaproteobacteria 28216|Betaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP k141_15983_2 391615.ABSJ01000059_gene2177 7.62e-57 179.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1J6ER@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional VL23_01195 - - - - - - - - - - - MerR_1 k141_7571_1 1288826.MSNKSG1_05481 1.19e-222 623.0 COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria,46B77@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases ygcU - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_10389_2 1288826.MSNKSG1_05466 7.16e-148 419.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,466GX@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_16632_2 1207076.ALAT01000030_gene90 2.39e-181 522.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1YZZY@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F Bifunctional purine biosynthesis protein PurH purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS k141_18751_1 936455.KI421499_gene5904 2.22e-44 169.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,2TQTY@28211|Alphaproteobacteria,3JT8P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235 k141_12535_1 292415.Tbd_1992 6.3e-11 59.7 COG4831@1|root,COG4831@2|Bacteria,1N55K@1224|Proteobacteria,2WC6F@28216|Betaproteobacteria,1KT5T@119069|Hydrogenophilales 119069|Hydrogenophilales S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_12535_2 207954.MED92_09121 8.34e-45 148.0 COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,1XKBQ@135619|Oceanospirillales 135619|Oceanospirillales S Lysine exporter protein (LYSE YGGA) - - - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE k141_8924_1 367336.OM2255_12512 7.33e-63 207.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0277 FAD FMN-containing dehydrogenases - - 1.1.2.4 ko:K00102 ko00620,map00620 - R00197 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_8350_1 1278309.KB907101_gene281 3.95e-244 680.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XIG4@135619|Oceanospirillales 135619|Oceanospirillales M secretion protein - - - ko:K12542 - M00330 - - ko00000,ko00002,ko02000,ko02044 3.A.1.109.4,8.A.1 - - Biotin_lipoyl_2,HlyD,HlyD_3,OEP k141_8350_2 1278309.KB907101_gene282 5.18e-164 470.0 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,1XIGH@135619|Oceanospirillales 135619|Oceanospirillales MU type I secretion outer membrane protein, TolC - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP,OmpA,SPOR k141_20792_2 1163409.UUA_17662 2.07e-42 157.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1X38Z@135614|Xanthomonadales 135614|Xanthomonadales H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE k141_11115_1 1049564.TevJSym_aa01810 1.09e-99 310.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Citrate transporter sac1 - - - - - - - - - - - CitMHS,TrkA_C k141_14488_1 105559.Nwat_1471 4.31e-112 325.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1WW24@135613|Chromatiales 135613|Chromatiales OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k141_14488_2 1121878.AUGL01000014_gene1703 2.94e-139 413.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_19453_1 1232683.ADIMK_1474 1.55e-65 215.0 COG0529@1|root,COG1218@1|root,COG0529@2|Bacteria,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,46612@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313 Inositol_P k141_4825_1 686340.Metal_2829 8.35e-34 135.0 COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,1RZ8P@1236|Gammaproteobacteria,1XG8B@135618|Methylococcales 135618|Methylococcales S Peptidase C13 family - - - - - - - - - - - - Peptidase_C13 k141_4825_2 1485544.JQKP01000010_gene821 1.98e-72 230.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,44V88@713636|Nitrosomonadales 28216|Betaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_17325_1 95619.PM1_0212800 5.75e-54 182.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E oxidoreductase - - - - - - - - - - - - DAO k141_17325_2 1232683.ADIMK_2081 3.91e-62 201.0 COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1S03A@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP k141_22228_1 225937.HP15_2273 7.53e-100 298.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_1359_1 1278309.KB907112_gene3343 6.55e-201 580.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XHJR@135619|Oceanospirillales 135619|Oceanospirillales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_1359_2 1278309.KB907112_gene3344 0.0 911.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1XI9U@135619|Oceanospirillales 135619|Oceanospirillales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_15179_2 1278309.KB907109_gene3262 1.84e-26 102.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,1XM3X@135619|Oceanospirillales 135619|Oceanospirillales P Rieske 2Fe-2S - - - - - - - - - - - - Rieske k141_15179_3 1187848.AJYQ01000095_gene1805 8.66e-07 48.5 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XWZM@135623|Vibrionales 135623|Vibrionales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k141_9615_1 519989.ECTPHS_02461 1.31e-19 95.9 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_8925_1 1499967.BAYZ01000067_gene6049 1.75e-94 285.0 COG1453@1|root,COG1453@2|Bacteria,2NNZZ@2323|unclassified Bacteria 2|Bacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_3442_1 1384056.N787_06465 7.79e-54 192.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RQ7X@1236|Gammaproteobacteria,1X4WC@135614|Xanthomonadales 135614|Xanthomonadales O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_10390_1 653733.Selin_0436 2.15e-39 149.0 COG3014@1|root,COG3014@2|Bacteria 2|Bacteria S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - k141_21555_1 1121405.dsmv_1445 1.21e-107 327.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MI6Q@213118|Desulfobacterales 28221|Deltaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_15984_1 998674.ATTE01000001_gene294 1.56e-162 465.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,45ZTU@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k141_5512_2 1278309.KB907105_gene1466 4.87e-98 289.0 COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,1S9RM@1236|Gammaproteobacteria,1XREU@135619|Oceanospirillales 135619|Oceanospirillales S Paraquat-inducible protein A - - - - - - - - - - - - PqiA k141_11116_1 83406.HDN1F_06620 1.47e-32 135.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1J4Z4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M lipoprotein lpoA GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07121 - - - - ko00000 - - - LppC k141_3443_1 1278309.KB907100_gene1985 4.65e-114 338.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1XHDD@135619|Oceanospirillales 135619|Oceanospirillales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI k141_8351_1 930169.B5T_04370 3.5e-07 51.6 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHXR@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM k141_8351_2 1278309.KB907100_gene2323 2.7e-58 187.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1XK0E@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component gtrA - - - - - - - - - - - DctQ k141_19454_1 472759.Nhal_2778 2.76e-95 280.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1WX8R@135613|Chromatiales 135613|Chromatiales I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA k141_22229_1 1121013.P873_06085 5.97e-83 256.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X4V4@135614|Xanthomonadales 135614|Xanthomonadales HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST k141_22229_2 472759.Nhal_2058 3.64e-65 214.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_6165_2 371731.Rsw2DRAFT_1441 3.78e-37 145.0 2DTIQ@1|root,33KIW@2|Bacteria 2|Bacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans k141_17326_1 1026882.MAMP_00745 9.85e-127 372.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,45ZTJ@72273|Thiotrichales 72273|Thiotrichales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k141_9616_1 644107.SL1157_A0171 1.35e-197 551.0 COG1175@1|root,COG1175@2|Bacteria,1MXK1@1224|Proteobacteria,2TUVU@28211|Alphaproteobacteria,4NB89@97050|Ruegeria 28211|Alphaproteobacteria P transport systems aglF - - ko:K10233 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - BPD_transp_1 k141_3444_1 1207075.PputUW4_01347 1.29e-07 54.3 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1S9JF@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Dsba oxidoreductase - - - ko:K07396 - - - - ko00000 - - - DSBA k141_8352_1 1123073.KB899242_gene990 1.49e-66 228.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1X4ST@135614|Xanthomonadales 135614|Xanthomonadales S Large extracellular alpha-helical protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1 k141_632_1 1049564.TevJSym_ax00490 1.91e-63 221.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k141_3454_1 1208321.D104_10960 2.11e-76 236.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales 135619|Oceanospirillales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_11929_1 1538295.JY96_18085 2.33e-08 55.8 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1KJQR@119065|unclassified Burkholderiales 28216|Betaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_11929_2 519989.ECTPHS_11345 1.32e-151 434.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1WW2U@135613|Chromatiales 135613|Chromatiales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k141_7039_1 998674.ATTE01000001_gene1773 3.44e-62 219.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,45ZMV@72273|Thiotrichales 72273|Thiotrichales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_2,OstA_C k141_14014_1 1122137.AQXF01000002_gene438 9.03e-83 255.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bkdA1 - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,OxoDH_E1alpha_N k141_14014_2 935261.JAGL01000010_gene1917 8.04e-19 84.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,43HA2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase bkdA2 - 1.2.4.4 ko:K00167 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_5666_2 755732.Fluta_3617 4.48e-31 117.0 COG1778@1|root,COG1778@2|Bacteria,4NGXC@976|Bacteroidetes,1HX0H@117743|Flavobacteriia,2PAX2@246874|Cryomorphaceae 976|Bacteroidetes S TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family - - 2.7.7.43,2.7.7.92,3.1.3.45 ko:K03270,ko:K21749 ko00520,ko00540,ko01100,map00520,map00540,map01100 M00063 R01117,R03350,R04215 RC00017,RC00152 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3,Hydrolase_3 k141_9124_1 1158756.AQXQ01000012_gene1808 0.000238 46.6 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_9124_2 371042.NG99_06620 2.49e-08 54.7 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,3X5VA@551|Erwinia 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404 GlutR_N,GlutR_dimer,Shikimate_DH k141_7751_1 580327.Tthe_1613 6.17e-20 94.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42EW1@68295|Thermoanaerobacterales 186801|Clostridia T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_757_1 228410.NE2298 4.44e-08 53.5 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,372D9@32003|Nitrosomonadales 28216|Betaproteobacteria I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_757_2 472759.Nhal_0765 1.17e-170 488.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_757_3 935863.AWZR01000004_gene433 4.37e-25 102.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1X3XQ@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_18184_1 1288826.MSNKSG1_03966 0.0 1327.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,464YY@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III alpha subunit dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_16795_1 243233.MCA2332 5.84e-80 252.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1XERM@135618|Methylococcales 135618|Methylococcales F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_16092_2 666684.AfiDRAFT_1591 1.19e-39 141.0 COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2TVD9@28211|Alphaproteobacteria,3JRWY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Ribosomal RNA adenine dimethylase pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_25,RrnaAD k141_16092_4 1137799.GZ78_05135 3.3e-17 76.6 2AXM7@1|root,31PMG@2|Bacteria,1RIYV@1224|Proteobacteria,1S732@1236|Gammaproteobacteria,1XKE9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_6325_1 1318628.MARLIPOL_14615 6.22e-34 128.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,4683Q@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the GSP D family rcpA - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - Secretin,T2SS-T3SS_pil_N k141_6325_2 1122197.ATWI01000008_gene3015 8.66e-30 121.0 COG3745@1|root,COG3745@2|Bacteria 2|Bacteria U Flp pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF k141_6325_3 1177179.A11A3_09105 2.04e-24 99.0 COG4961@1|root,COG4961@2|Bacteria,1NMP4@1224|Proteobacteria 1224|Proteobacteria U PFAM TadE family protein - - - - - - - - - - - - TadE k141_5696_2 1208323.B30_06731 2.89e-38 142.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase cckA - 2.7.13.3 ko:K13587 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg k141_2165_2 472759.Nhal_2113 5.84e-14 68.2 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,1S6VD@1236|Gammaproteobacteria,1X0VV@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_15453_1 666685.R2APBS1_2386 8.09e-58 193.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1X4IS@135614|Xanthomonadales 135614|Xanthomonadales V COG1566 Multidrug resistance efflux pump - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_D23 k141_782_1 994479.GL877878_gene3273 3.74e-18 83.2 COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria,4DYF0@85010|Pseudonocardiales 201174|Actinobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k141_13355_1 1278309.KB907099_gene2838 2.18e-91 275.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1RS3Z@1236|Gammaproteobacteria,1XKTC@135619|Oceanospirillales 135619|Oceanospirillales S Sodium Bile acid symporter family - - - - - - - - - - - - Mem_trans k141_17486_1 987059.RBXJA2T_14936 2.19e-68 217.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,1KJ4M@119065|unclassified Burkholderiales 28216|Betaproteobacteria S associated with various cellular activities moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_6351_1 740709.A10D4_02057 3.44e-13 67.4 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,2QFFT@267893|Idiomarinaceae 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 k141_11951_1 999611.KI421504_gene858 3.52e-53 187.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,27ZXA@191028|Leisingera 28211|Alphaproteobacteria K RNB rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - RNB,S1 k141_2166_2 1144307.PMI04_03213 9.4e-13 68.2 COG1595@1|root,COG1595@2|Bacteria,1N1G3@1224|Proteobacteria,2UBTI@28211|Alphaproteobacteria,2K7GD@204457|Sphingomonadales 204457|Sphingomonadales K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_18910_1 1122604.JONR01000007_gene2770 3.58e-53 177.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1X46K@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N k141_18910_2 261292.Nit79A3_3538 3.96e-42 149.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,3725K@32003|Nitrosomonadales 28216|Betaproteobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_10548_1 458817.Shal_1096 2.55e-91 281.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,2QAN0@267890|Shewanellaceae 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_18214_2 1288826.MSNKSG1_00571 5.15e-162 455.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,4640C@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_18214_3 1288826.MSNKSG1_00576 1.15e-92 271.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,4677Q@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_18214_5 1288826.MSNKSG1_00586 7.43e-49 162.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1S61M@1236|Gammaproteobacteria,467SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_15455_2 1449350.OCH239_06235 5.66e-95 292.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,4KNFE@93682|Roseivivax 28211|Alphaproteobacteria E Belongs to the GMC oxidoreductase family MA20_44990 - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N k141_11273_1 1278309.KB907100_gene1854 4.24e-15 73.2 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1XHEY@135619|Oceanospirillales 135619|Oceanospirillales P transporter corC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_11273_2 1278309.KB907100_gene1855 1.12e-292 807.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XHUC@135619|Oceanospirillales 135619|Oceanospirillales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k141_11273_3 1278309.KB907100_gene1856 4.13e-97 285.0 COG2888@1|root,COG2888@2|Bacteria,1RITX@1224|Proteobacteria,1S87K@1236|Gammaproteobacteria,1XK6X@135619|Oceanospirillales 135619|Oceanospirillales J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_11273_4 1278309.KB907100_gene1857 2.1e-181 527.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XHWN@135619|Oceanospirillales 135619|Oceanospirillales J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k141_5698_1 1124983.PFLCHA0_c57820 5.86e-12 71.2 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1YQFM@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria T response regulator pilG - - ko:K02657,ko:K03413 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_20332_1 1123360.thalar_01317 3.58e-94 281.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_20332_2 1294273.roselon_00265 9.48e-35 126.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE k141_783_1 857087.Metme_0465 9.12e-46 160.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1XE7F@135618|Methylococcales 135618|Methylococcales HL TIGRFAM Mutator MutT protein - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX_4,TMP-TENI k141_16819_1 1122599.AUGR01000024_gene1354 2.96e-20 86.3 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1S70H@1236|Gammaproteobacteria,1XKFQ@135619|Oceanospirillales 135619|Oceanospirillales S Invasion gene expression up-regulator - - - - - - - - - - - - SirB k141_16819_3 207954.MED92_01739 2.42e-61 193.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XJQQ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 k141_16819_4 1380393.JHVP01000004_gene576 2.22e-08 59.3 COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4ETKN@85013|Frankiales 201174|Actinobacteria C PFAM CBS domain containing protein - - - - - - - - - - - - BON,CBS k141_15456_1 399739.Pmen_4062 2.02e-11 65.9 COG0811@1|root,COG0811@2|Bacteria,1QHY6@1224|Proteobacteria,1SWH6@1236|Gammaproteobacteria,1YCVD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_15456_2 697282.Mettu_3548 3.38e-16 74.7 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XFE7@135618|Methylococcales 135618|Methylococcales S Tol-Pal system-associated acyl-CoA thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT k141_14739_1 1278309.KB907105_gene1511 3.27e-140 405.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1XJH2@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the GcvT family - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_14739_2 1278309.KB907105_gene1512 1.78e-180 504.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XICF@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_14739_3 1278309.KB907105_gene1513 2.72e-158 447.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1XIR9@135619|Oceanospirillales 135619|Oceanospirillales P Sulfurtransferase glpE - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k141_14739_4 1278309.KB907105_gene1514 3.05e-246 696.0 COG1639@1|root,COG1639@2|Bacteria,1R9QK@1224|Proteobacteria,1S1P7@1236|Gammaproteobacteria,1XJ0Y@135619|Oceanospirillales 135619|Oceanospirillales T Metal-dependent hydrolase - - - - - - - - - - - - HDOD k141_14739_5 1278309.KB907105_gene1515 6.01e-152 432.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XHIQ@135619|Oceanospirillales 135619|Oceanospirillales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_9832_1 1288826.MSNKSG1_05231 5.59e-191 545.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,464VK@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_9832_2 1288826.MSNKSG1_05236 1.24e-135 385.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,467BW@72275|Alteromonadaceae 1236|Gammaproteobacteria M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k141_9832_3 1288826.MSNKSG1_05241 5.25e-145 412.0 COG0739@1|root,COG0739@2|Bacteria,1QZBB@1224|Proteobacteria,1T44D@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB - - - - - - - - - - - - - k141_12636_1 1278309.KB907102_gene183 3.78e-190 530.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,1RZ0W@1236|Gammaproteobacteria,1XISP@135619|Oceanospirillales 135619|Oceanospirillales E Prephenate dehydratase - - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT k141_12636_2 1278309.KB907102_gene184 3.62e-151 426.0 COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,1XJFV@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylas_C,SpoU_methylase k141_12636_3 1278309.KB907102_gene185 1.5e-93 294.0 COG4191@1|root,COG4191@2|Bacteria,1R4YU@1224|Proteobacteria,1RSG2@1236|Gammaproteobacteria,1XI49@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 k141_13356_1 330214.NIDE1482 1.67e-42 160.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity mltC GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08306,ko:K08308,ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iAF1260.b1193,iB21_1397.B21_01178,iBWG_1329.BWG_1018,iECBD_1354.ECBD_2429,iECB_1328.ECB_01168,iECDH10B_1368.ECDH10B_1246,iECDH1ME8569_1439.ECDH1ME8569_1132,iECD_1391.ECD_01168,iEcDH1_1363.EcDH1_2455,iEcolC_1368.EcolC_2432,iG2583_1286.G2583_3622,iJO1366.b1193,iUMNK88_1353.UMNK88_1507,iUMNK88_1353.UMNK88_3661,iY75_1357.Y75_RS06225 DUF3393,SLT k141_1475_1 1288826.MSNKSG1_10758 0.0 868.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,464HR@72275|Alteromonadaceae 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_5699_1 1190603.AJYD01000024_gene556 1.77e-16 78.6 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1XWV1@135623|Vibrionales 135623|Vibrionales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_5699_2 395493.BegalDRAFT_1390 4.72e-76 235.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,4609Z@72273|Thiotrichales 72273|Thiotrichales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_7054_1 1348114.OM33_05620 7.22e-160 459.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,2PZXF@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Belongs to the GARS family purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 GARS_A,GARS_C,GARS_N k141_6353_2 998674.ATTE01000001_gene2008 8.48e-14 70.1 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,462UE@72273|Thiotrichales 72273|Thiotrichales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_21669_1 1116375.VEJY3_20381 1.62e-165 483.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1S02D@1236|Gammaproteobacteria,1Y3B1@135623|Vibrionales 135623|Vibrionales C Dehydrogenase E1 component - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_21669_2 425104.Ssed_2176 4.25e-108 319.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,2QBZN@267890|Shewanellaceae 1236|Gammaproteobacteria C Transketolase, pyrimidine binding domain pdhB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_4945_1 1278309.KB907102_gene266 2.98e-178 530.0 COG1196@1|root,COG1196@2|Bacteria,1QUTY@1224|Proteobacteria,1T351@1236|Gammaproteobacteria,1XHM7@135619|Oceanospirillales 135619|Oceanospirillales D DNA replication and repair protein RecF - - - - - - - - - - - - AAA_29,SbcCD_C k141_2864_1 1288826.MSNKSG1_13202 3.27e-308 843.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1RZ5Q@1236|Gammaproteobacteria,46767@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k141_2864_2 1288826.MSNKSG1_13207 4.26e-101 293.0 COG2885@1|root,COG2885@2|Bacteria,1RAB7@1224|Proteobacteria,1SS9U@1236|Gammaproteobacteria,468H0@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - - - - - - - - - - OmpA k141_2864_3 1288826.MSNKSG1_13212 3.92e-89 261.0 COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,4682P@72275|Alteromonadaceae 1236|Gammaproteobacteria S relative of glutathione S-transferase, MAPEG superfamily yecN - - ko:K07136 - - - - ko00000 - - - MAPEG k141_2864_4 1288826.MSNKSG1_13217 7.63e-46 148.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,468ED@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc k141_2864_5 1288826.MSNKSG1_13222 5.47e-66 206.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,466JE@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_18216_1 391615.ABSJ01000039_gene1844 6.74e-118 345.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1J5A9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_2167_2 1278309.KB907103_gene994 1.27e-156 444.0 COG2865@1|root,COG2865@2|Bacteria,1R611@1224|Proteobacteria,1S0MT@1236|Gammaproteobacteria,1XNKS@135619|Oceanospirillales 135619|Oceanospirillales K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 k141_15457_1 1141662.OOA_11618 3.23e-15 79.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,3Z8HM@586|Providencia 1236|Gammaproteobacteria S Psort location CytoplasmicMembrane, score lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 YjgP_YjgQ k141_15457_2 572477.Alvin_0636 2.65e-09 58.2 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales 135613|Chromatiales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N k141_67_1 1121116.KB894766_gene285 5.37e-14 73.2 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae 28216|Betaproteobacteria T Adenylate cyclase cyaA - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_67_2 1042377.AFPJ01000037_gene2939 2.84e-42 156.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_14740_2 351348.Maqu_1985 5.33e-10 60.8 COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,468FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG3190 Flagellar biogenesis protein fliO - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_11274_1 648757.Rvan_1810 7.76e-21 93.2 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria,3N8PV@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria U PFAM Type II secretion system F domain pilC - - ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSF k141_11274_2 1120973.AQXL01000113_gene779 6.16e-15 80.9 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,278UP@186823|Alicyclobacillaceae 91061|Bacilli NU type II secretion system protein E pilB - - ko:K02243,ko:K02652 - M00429 - - ko00000,ko00002,ko02035,ko02044 3.A.14.1,3.A.15.2 - - T2SSE,T2SSE_N k141_13488_4 1288826.MSNKSG1_04416 6.22e-114 330.0 COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,46711@72275|Alteromonadaceae 1236|Gammaproteobacteria P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_16972_1 1288826.MSNKSG1_14992 2.06e-108 322.0 COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,1RMHC@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_4 k141_9267_1 522772.Dacet_0983 1.13e-65 207.0 COG0412@1|root,COG0412@2|Bacteria,2GF4A@200930|Deferribacteres 200930|Deferribacteres Q Prolyl oligopeptidase family - - - - - - - - - - - - DLH k141_2287_1 1122201.AUAZ01000046_gene2159 1.96e-157 452.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RZG1@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_2287_2 1122201.AUAZ01000046_gene2160 1.26e-43 149.0 COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,1SDQU@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_2287_3 1232683.ADIMK_2116 6.75e-232 648.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,469IV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_2287_4 1144310.PMI07_004139 6.15e-120 348.0 COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,4B87T@82115|Rhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase MA20_05990 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 k141_7942_1 644801.Psest_3834 4.05e-116 349.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,1Z146@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C Rubredoxin reductase rubB - 1.18.1.1 ko:K05297 ko00071,map00071 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2,Rubredoxin k141_21205_2 395493.BegalDRAFT_3005 3.08e-53 176.0 COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,1S54H@1236|Gammaproteobacteria,462T3@72273|Thiotrichales 72273|Thiotrichales S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_21205_3 396588.Tgr7_2428 8.92e-15 71.6 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1WWQJ@135613|Chromatiales 135613|Chromatiales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_13489_1 519989.ECTPHS_07107 2.67e-13 66.2 2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,1SDWS@1236|Gammaproteobacteria,1X22K@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2818) - - - - - - - - - - - - DUF2818 k141_13489_2 1144319.PMI16_03542 1.4e-24 103.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,472IA@75682|Oxalobacteraceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k141_16973_1 883078.HMPREF9695_03210 8.29e-10 65.5 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria,3JRJ0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_4450_1 1120999.JONM01000002_gene749 5.17e-16 82.0 COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,2KPJH@206351|Neisseriales 206351|Neisseriales H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group - - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib k141_1643_1 1278309.KB907101_gene642 1.36e-85 279.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XI5I@135619|Oceanospirillales 135619|Oceanospirillales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF k141_1643_2 1278309.KB907101_gene643 6.73e-185 524.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1XHW4@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_8609_1 443598.AUFA01000001_gene1361 1.32e-23 97.8 COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2U7AD@28211|Alphaproteobacteria,3JYQU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_8609_2 1208583.COMX_01575 2.81e-09 62.4 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2JQCS@204441|Rhodospirillales 204441|Rhodospirillales O Thioredoxin - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_14190_1 1116472.MGMO_112c00130 1.21e-87 265.0 2DQ6U@1|root,3350B@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4393) - - - - - - - - - - - - DUF4393 k141_20494_1 314275.MADE_1012650 4.28e-36 128.0 COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,1S5YP@1236|Gammaproteobacteria,467DE@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 fkpB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03774 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_20494_2 1265313.HRUBRA_01672 8.86e-154 439.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1J4JS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 LYTB k141_21855_2 1120963.KB894491_gene737 2.62e-135 387.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the SAICAR synthetase family purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 SAICAR_synt k141_21855_3 870187.Thini_2860 1.09e-102 305.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,460KN@72273|Thiotrichales 72273|Thiotrichales S of the beta-lactamase superfamily I - - - - - - - - - - - - Lactamase_B_2 k141_21855_4 314607.KB13_264 1.24e-07 55.8 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria 28216|Betaproteobacteria M (Lipo)protein nlpB - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 k141_926_1 1026882.MAMP_02537 5.73e-47 160.0 COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,461KZ@72273|Thiotrichales 72273|Thiotrichales S HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP k141_926_2 1168067.JAGP01000001_gene588 2.29e-16 76.6 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,460DZ@72273|Thiotrichales 72273|Thiotrichales G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_21207_1 377629.TERTU_1556 3.73e-17 82.4 COG4886@1|root,COG4886@2|Bacteria,1NBJ1@1224|Proteobacteria,1SDV2@1236|Gammaproteobacteria,2PPRU@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Leucine Rich Repeat - - - - - - - - - - - - LRR_1,LRR_6 k141_7203_1 1278309.KB907104_gene956 2.37e-243 677.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XHC6@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k141_7203_2 1278309.KB907104_gene955 3.36e-168 482.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1XJ9V@135619|Oceanospirillales 135619|Oceanospirillales D peptidase - - - - - - - - - - - - Peptidase_M23 k141_7203_3 1278309.KB907104_gene954 0.0 889.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XH27@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N k141_7203_4 1278309.KB907104_gene953 1.28e-75 228.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1XKHI@135619|Oceanospirillales 135619|Oceanospirillales P Sulfurtransferase - - - - - - - - - - - - Rhodanese k141_7203_5 314262.MED193_14037 1.2e-21 87.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,2P3IX@2433|Roseobacter 28211|Alphaproteobacteria C Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_7203_6 1278309.KB907104_gene951 3.89e-95 279.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XK48@135619|Oceanospirillales 135619|Oceanospirillales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k141_10726_1 1278309.KB907101_gene282 3.84e-15 74.3 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,1XIGH@135619|Oceanospirillales 135619|Oceanospirillales MU type I secretion outer membrane protein, TolC - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP,OmpA,SPOR k141_10726_2 1278309.KB907101_gene283 1.04e-104 308.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XIBX@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 k141_17681_1 580332.Slit_2156 6.33e-34 122.0 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,44WFC@713636|Nitrosomonadales 28216|Betaproteobacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - - k141_17681_2 572477.Alvin_1850 1.17e-37 131.0 2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,1S4GF@1236|Gammaproteobacteria,1WY9W@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF3775) - - - - - - - - - - - - DUF3775 k141_4452_1 351348.Maqu_1177 1.14e-44 153.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,4648H@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_21856_1 1535422.ND16A_0646 3.73e-22 100.0 COG0758@1|root,COG0758@2|Bacteria,1N2UI@1224|Proteobacteria 1224|Proteobacteria LU DNA mediated transformation - - - - - - - - - - - - - k141_927_1 545276.KB898724_gene2040 6.09e-13 69.3 COG0526@1|root,COG0526@2|Bacteria,1NUNF@1224|Proteobacteria,1SNKC@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_927_2 396588.Tgr7_0116 1.67e-138 396.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1WX13@135613|Chromatiales 135613|Chromatiales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_16976_1 1173020.Cha6605_1920 5.76e-36 134.0 COG2211@1|root,COG2211@2|Bacteria,1GQN5@1117|Cyanobacteria 1117|Cyanobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_11419_1 314345.SPV1_04098 7.35e-41 139.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria 1224|Proteobacteria P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k141_11419_3 1049564.TevJSym_am00160 7.96e-61 212.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,1J9QI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_7943_1 1041146.ATZB01000033_gene518 1.24e-10 65.1 COG2771@1|root,COG2771@2|Bacteria,1N6UR@1224|Proteobacteria,2V8KR@28211|Alphaproteobacteria,4BE51@82115|Rhizobiaceae 28211|Alphaproteobacteria K COG2771 DNA-binding HTH domain-containing proteins - - - - - - - - - - - - Autoind_bind,GerE k141_7943_2 1411685.U062_00271 5.79e-40 146.0 COG0584@1|root,COG0584@2|Bacteria,1QJ6D@1224|Proteobacteria,1TH3Y@1236|Gammaproteobacteria,1J6E4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family - - - - - - - - - - - - GDPD k141_7943_3 1123279.ATUS01000001_gene2618 7.32e-39 141.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1J4QT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Glycerol-3-phosphate dehydrogenase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_2289_1 349521.HCH_06149 0.000776 41.2 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XHWB@135619|Oceanospirillales 135619|Oceanospirillales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - ko:K02454,ko:K12276 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k141_2289_2 396588.Tgr7_3279 2.54e-178 503.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1WW5T@135613|Chromatiales 135613|Chromatiales F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_20496_1 929562.Emtol_2901 2.82e-17 81.6 28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,47JAX@768503|Cytophagia 976|Bacteroidetes S S1 P1 nuclease - - - - - - - - - - - - S1-P1_nuclease,Zn_dep_PLPC k141_20496_2 1048983.EL17_06615 1.08e-25 97.1 COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia 976|Bacteroidetes J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_21857_1 396588.Tgr7_1848 2.7e-22 95.5 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales 135613|Chromatiales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k141_21857_2 243231.GSU1295 7.77e-22 94.0 COG0834@1|root,COG0834@2|Bacteria,1N0VS@1224|Proteobacteria,42TK3@68525|delta/epsilon subdivisions,2WQS6@28221|Deltaproteobacteria 28221|Deltaproteobacteria ET Bacterial extracellular solute-binding proteins, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_4453_1 1278309.KB907099_gene2473 5.82e-119 344.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,1XHCX@135619|Oceanospirillales 135619|Oceanospirillales C Cysteine-rich domain - - - ko:K18928 - - - - ko00000 - - - CCG k141_4453_2 1278309.KB907099_gene2472 2.03e-81 253.0 COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,1XHUV@135619|Oceanospirillales 135619|Oceanospirillales C Domain of unknown function (DUF3390) - - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_7,Fer4_8,LUD_dom k141_10727_2 1288826.MSNKSG1_09933 2.98e-20 89.4 COG5488@1|root,COG5488@2|Bacteria,1N2M1@1224|Proteobacteria,1S9XR@1236|Gammaproteobacteria,468JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 k141_2310_1 1278309.KB907100_gene2177 4.22e-125 387.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1XIXK@135619|Oceanospirillales 135619|Oceanospirillales C COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits - - - - - - - - - - - - POR k141_9969_1 596151.DesfrDRAFT_2501 2.01e-43 152.0 COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,42NAT@68525|delta/epsilon subdivisions,2WPPB@28221|Deltaproteobacteria,2MBTW@213115|Desulfovibrionales 28221|Deltaproteobacteria V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_1672_1 754477.Q7C_897 5.98e-49 167.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales 72273|Thiotrichales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_1672_2 243233.MCA1366 9.2e-07 53.1 2DRM4@1|root,33C8W@2|Bacteria,1NQ8K@1224|Proteobacteria,1SGVH@1236|Gammaproteobacteria,1XFRG@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - k141_19760_1 292415.Tbd_2358 1.35e-124 360.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,2WGQC@28216|Betaproteobacteria,1KRMT@119069|Hydrogenophilales 119069|Hydrogenophilales C Oxidoreductase FAD-binding domain - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_11433_1 1123247.AUIJ01000001_gene1834 9e-32 118.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer k141_11433_2 1461694.ATO9_14020 2.08e-56 177.0 COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2U9AH@28211|Alphaproteobacteria,2PEAK@252301|Oceanicola 28211|Alphaproteobacteria J Putative tRNA binding domain csaA - - ko:K06878 - - - - ko00000 - - - tRNA_bind k141_11433_3 1188256.BASI01000002_gene3241 2.47e-09 57.8 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,3FDTV@34008|Rhodovulum 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain gyaR2 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 ko:K00015,ko:K00050,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R00717,R01388,R01392,R01739 RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_7959_1 314345.SPV1_00095 2.47e-84 279.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_10737_1 95619.PM1_0204750 5.97e-52 182.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria 1236|Gammaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_17700_1 1121405.dsmv_0647 5.79e-53 178.0 COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2MJCH@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_17700_2 1380387.JADM01000003_gene2642 5.01e-34 124.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,1S21F@1236|Gammaproteobacteria,1XJVG@135619|Oceanospirillales 135619|Oceanospirillales S TRAP transporter T-component - - - - - - - - - - - - TAtT k141_2311_2 157783.LK03_20535 2.78e-44 153.0 COG1414@1|root,COG1414@2|Bacteria,1RDS5@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR k141_1673_1 857087.Metme_3856 1.1e-97 287.0 2CRCE@1|root,32SNU@2|Bacteria,1N3U1@1224|Proteobacteria,1T14C@1236|Gammaproteobacteria,1XG28@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - k141_19761_1 367336.OM2255_11910 7.64e-55 192.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase resE - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg,SSF k141_7228_2 717773.Thicy_0276 1.56e-33 122.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,46143@72273|Thiotrichales 72273|Thiotrichales S membrane transporter protein - - - ko:K07090,ko:K11312 - - - - ko00000 - - - TauE k141_20522_1 99598.Cal7507_2482 3.82e-30 136.0 COG2931@1|root,COG2931@2|Bacteria,1G4X1@1117|Cyanobacteria,1HTX8@1161|Nostocales 1117|Cyanobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - Calx-beta,DUF4347,He_PIG,HemolysinCabind k141_19112_1 1528106.JRJE01000005_gene1437 8.2e-51 174.0 COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2TV9J@28211|Alphaproteobacteria,2JQI6@204441|Rhodospirillales 204441|Rhodospirillales E L-asparaginase II - - - - - - - - - - - - Asparaginase_II k141_19112_2 493475.GARC_2626 1.57e-96 296.0 COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria 1224|Proteobacteria F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C k141_9970_1 697282.Mettu_0287 5.37e-42 163.0 COG1331@1|root,COG4233@1|root,COG1331@2|Bacteria,COG4233@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1XE8M@135618|Methylococcales 135618|Methylococcales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - DsbC,Thioredox_DsbH k141_7960_2 1117958.PE143B_0108385 2.71e-68 213.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050 Formyl_trans_N k141_2312_1 794846.AJQU01000099_gene3645 2.21e-81 251.0 COG1172@1|root,COG1172@2|Bacteria,1MUDF@1224|Proteobacteria,2U4K2@28211|Alphaproteobacteria,4B86Z@82115|Rhizobiaceae 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_12807_1 1162668.LFE_1592 2.18e-31 117.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins ydaF_1 - - - - - - - - - - - Acetyltransf_3 k141_401_1 396588.Tgr7_0076 7.78e-28 114.0 COG2199@1|root,COG3706@2|Bacteria,1QUY1@1224|Proteobacteria,1SZ80@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,HAMP k141_18493_1 314231.FP2506_12854 1.27e-54 187.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria,2PKIF@255475|Aurantimonadaceae 28211|Alphaproteobacteria C FAD binding domain - - 1.1.3.8,1.1.98.3 ko:K00103,ko:K16653 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 k141_17827_1 713586.KB900536_gene1208 2.78e-63 227.0 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1WZX9@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_19255_1 713586.KB900536_gene2820 4.37e-80 250.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 k141_11543_1 1117314.PCIT_05024 1.3e-65 207.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,2Q32F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1,rve,rve_3 k141_11543_2 1219072.VHA01S_030_00010 1.45e-49 158.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S6KR@1236|Gammaproteobacteria,1Y2SC@135623|Vibrionales 135623|Vibrionales L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 k141_9395_2 572477.Alvin_2800 1.13e-85 258.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1WW4H@135613|Chromatiales 135613|Chromatiales J PFAM methyltransferase small - - - - - - - - - - - - MTS,MTS_N k141_9395_3 1163617.SCD_n02017 1.42e-14 72.8 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria 28216|Betaproteobacteria P Sulfate transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_1102_2 644801.Psest_0049 7.56e-80 241.0 COG3832@1|root,COG3832@2|Bacteria,1MZ7K@1224|Proteobacteria 1224|Proteobacteria S Activator of Hsp90 ATPase - - - - - - - - - - - - AHSA1 k141_7353_1 715451.ambt_21740 1.07e-119 357.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,46490@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.10.3.10,1.9.3.1 ko:K02274,ko:K02298 ko00190,ko01100,map00190,map01100 M00155,M00417 R00081,R11335 RC00016,RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6 - iJN746.PP_0104 COX1 k141_8124_2 998674.ATTE01000001_gene2455 3.8e-149 433.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k141_15765_1 1348114.OM33_07920 1.84e-81 254.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,2Q120@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_15765_2 1499686.BN1079_00172 7.11e-72 224.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria N this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine motC - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_17111_1 1131553.JIBI01000056_gene161 3.79e-111 326.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,372US@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF692) - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_16403_1 1313301.AUGC01000007_gene544 5.45e-53 186.0 COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 k141_4610_1 246200.SPO3347 2.45e-29 110.0 COG3755@1|root,COG3755@2|Bacteria,1N0VR@1224|Proteobacteria,2UC85@28211|Alphaproteobacteria,4NCPK@97050|Ruegeria 28211|Alphaproteobacteria S Lysozyme inhibitor LprI - - - - - - - - - - - - LprI k141_14304_1 765912.Thimo_0822 6.48e-122 369.0 COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,1S5D2@1236|Gammaproteobacteria,1WYVS@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_2481_1 519989.ECTPHS_02204 6.13e-13 70.5 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales 135613|Chromatiales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri,YfiO k141_2481_2 472759.Nhal_0184 1.98e-46 157.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales 135613|Chromatiales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_2481_3 224914.BMEI0339 6.26e-13 73.2 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,1J1M8@118882|Brucellaceae 28211|Alphaproteobacteria U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_11556_1 580332.Slit_1237 7.02e-105 325.0 COG2199@1|root,COG2199@2|Bacteria,1P29Y@1224|Proteobacteria,2W170@28216|Betaproteobacteria 28216|Betaproteobacteria T Diverse 7TM receptor transmembrane region - - - - - - - - - - - - 7TMR-DISM_7TM,GGDEF k141_6634_1 1123360.thalar_00118 1.35e-54 177.0 COG3916@1|root,COG3916@2|Bacteria,1MWPW@1224|Proteobacteria,2TVJ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Acyl-homoserine-lactone synthase raiI - 2.3.1.184 ko:K20249 ko00270,ko01100,ko02024,map00270,map01100,map02024 - R08940 RC00021,RC00039 ko00000,ko00001,ko01000 - - - Autoind_synth k141_3866_1 1049564.TevJSym_ae00650 4.06e-97 289.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase k141_3866_2 2340.JV46_02960 6.99e-20 87.8 COG0398@1|root,COG0607@1|root,COG0398@2|Bacteria,COG0607@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P SNARE associated Golgi protein ydjX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Rhodanese,SNARE_assoc k141_17856_2 999541.bgla_1g05620 1.98e-35 127.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,1K1WW@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA k141_15029_1 1278309.KB907103_gene1185 4.62e-94 278.0 COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria,1XJ44@135619|Oceanospirillales 135619|Oceanospirillales K GntR family transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_15029_2 1278309.KB907103_gene1186 4.99e-162 457.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,1XI1U@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase k141_19275_1 388739.RSK20926_21824 3.09e-19 86.3 COG2113@1|root,COG2113@2|Bacteria,1MWZU@1224|Proteobacteria,2TTPN@28211|Alphaproteobacteria,2P2T5@2433|Roseobacter 28211|Alphaproteobacteria E COG2113 ABC-type proline glycine betaine transport systems, periplasmic components proX - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_19275_2 391619.PGA1_c33740 1.09e-77 238.0 COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,2TRGQ@28211|Alphaproteobacteria,34G0E@302485|Phaeobacter 28211|Alphaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21645 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_19897_1 62928.azo3555 1.89e-29 127.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,2KVFE@206389|Rhodocyclales 206389|Rhodocyclales H COG4206 Outer membrane cobalamin receptor protein - - - ko:K02014,ko:K16092 - - - - ko00000,ko02000 1.B.14,1.B.14.3 - - Plug,TonB_dep_Rec k141_9410_1 1166018.FAES_3546 1.02e-26 109.0 COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,47MXF@768503|Cytophagia 976|Bacteroidetes G Inward rectifier potassium channel irk - - ko:K08715 - - - - ko00000,ko02000 1.A.2.2 - - IRK k141_5293_1 1116472.MGMO_61c00130 8.57e-46 156.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1XEP3@135618|Methylococcales 135618|Methylococcales S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase k141_5293_3 1163408.UU9_12897 6.36e-56 202.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 k141_12285_1 203122.Sde_1879 1.24e-50 190.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,4645X@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_3231_1 765914.ThisiDRAFT_1725 1.01e-234 654.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase k141_13666_1 1123368.AUIS01000001_gene1994 1.8e-63 204.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,2NDJ3@225057|Acidithiobacillales 225057|Acidithiobacillales NT Two component signalling adaptor domain - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_8750_1 1278309.KB907099_gene2693 0.0 920.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XH4X@135619|Oceanospirillales 135619|Oceanospirillales C NADH flavin oxidoreductase NADH oxidase - - - ko:K21833 - - - - ko00000 - - - Oxidored_FMN,Pyr_redox_2 k141_16405_1 335543.Sfum_1795 5.73e-100 305.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MRHE@213462|Syntrophobacterales 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_8142_1 644107.SL1157_3365 2.42e-97 292.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,4N9XY@97050|Ruegeria 28211|Alphaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_13667_1 582744.Msip34_0462 7.51e-55 182.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,2KKDP@206350|Nitrosomonadales 206350|Nitrosomonadales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_10889_1 269799.Gmet_2955 3e-21 89.0 COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,43C47@68525|delta/epsilon subdivisions,2WV4E@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_25 k141_10889_2 2340.JV46_02680 6.23e-112 346.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1J9D0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - DsbC,Thioredox_DsbH k141_419_1 1218076.BAYB01000007_gene1279 4.1e-05 45.1 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,2VIQ6@28216|Betaproteobacteria,1K562@119060|Burkholderiaceae 28216|Betaproteobacteria KQ GAF domain acxR - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_419_2 1268068.PG5_13740 4.44e-130 404.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_419_3 1278309.KB907100_gene2314 0.0 1015.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XHD3@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_419_4 1278309.KB907100_gene2313 1.37e-253 704.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1XHJE@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k141_419_5 1278309.KB907100_gene2312 9.74e-73 224.0 COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,1RS6X@1236|Gammaproteobacteria,1XITG@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator, TrmB - - - - - - - - - - - - TrmB k141_15767_1 305900.GV64_15180 2.5e-88 269.0 28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,1RNKD@1236|Gammaproteobacteria,1XNW3@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15767_2 1535422.ND16A_0003 1.47e-17 75.9 2E3CN@1|root,32YBX@2|Bacteria,1N716@1224|Proteobacteria,1SEFN@1236|Gammaproteobacteria,2Q784@267889|Colwelliaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9411_1 388739.RSK20926_12199 3.45e-26 106.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_9411_2 911045.PSE_1835 1.73e-64 204.0 COG3090@1|root,COG3090@2|Bacteria,1R97M@1224|Proteobacteria,2URFW@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_6635_1 743721.Psesu_1988 5.02e-14 71.2 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1X76E@135614|Xanthomonadales 135614|Xanthomonadales NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_6635_2 762983.HMPREF9444_01452 7.78e-40 139.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1Y3WU@135624|Aeromonadales 135624|Aeromonadales K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_2483_1 69279.BG36_10200 1.84e-128 385.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,43IHT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I Methylmalonyl-CoA mutase bhbA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase k141_8751_1 760011.Spico_0376 2.54e-16 79.0 COG2270@1|root,COG2270@2|Bacteria,2J9X6@203691|Spirochaetes 203691|Spirochaetes S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_8751_3 264198.Reut_B4449 6.12e-13 69.3 28IJW@1|root,2Z8KR@2|Bacteria,1R45I@1224|Proteobacteria,2VK7H@28216|Betaproteobacteria,1K1WZ@119060|Burkholderiaceae 28216|Betaproteobacteria S signal peptide protein - - - - - - - - - - - - - k141_10148_1 1288826.MSNKSG1_16551 6.27e-246 682.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_10148_2 1288826.MSNKSG1_16546 4.77e-269 738.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,4658N@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - iEcE24377_1341.EcE24377A_1810 AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_10148_3 1288826.MSNKSG1_16541 6.62e-56 174.0 COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria,4682B@72275|Alteromonadaceae 1236|Gammaproteobacteria C NAD NADP transhydrogenase alpha subunit - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM k141_10148_4 1288826.MSNKSG1_16536 2.48e-309 846.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB k141_10148_5 1288826.MSNKSG1_16531 1.02e-40 139.0 COG1556@1|root,COG1556@2|Bacteria,1RJ6A@1224|Proteobacteria,1RRSN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LUD domain ykgG - - ko:K00782 - - - - ko00000 - - - LUD_dom k141_3233_1 1297863.APJF01000008_gene570 5.46e-90 273.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2TR8G@28211|Alphaproteobacteria,3JSHE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k141_3233_2 1401078.HMPREF2140_06735 1.32e-13 71.2 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,2FNA5@200643|Bacteroidia 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k141_5295_2 999541.bgla_1g33190 1.05e-70 218.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,1K2BA@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC k141_4612_1 491952.Mar181_3407 1.82e-65 208.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1XI8S@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_11557_1 367336.OM2255_13339 9.18e-97 295.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB k141_11557_2 1188256.BASI01000005_gene1669 5.44e-160 465.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,3FCQX@34008|Rhodovulum 28211|Alphaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM k141_3869_1 1122207.MUS1_05220 6.4e-38 145.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k141_15768_1 1120999.JONM01000031_gene3210 2.84e-30 126.0 COG2199@1|root,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,2VK4W@28216|Betaproteobacteria,2KQZH@206351|Neisseriales 206351|Neisseriales T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg k141_3234_2 177439.DP0087 2.86e-41 150.0 COG0318@1|root,COG0318@2|Bacteria,1QVGC@1224|Proteobacteria,43BUA@68525|delta/epsilon subdivisions 1224|Proteobacteria IQ AMP-binding enzyme C-terminal domain - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding k141_14307_1 1121440.AUMA01000008_gene802 3.07e-31 113.0 COG0440@1|root,COG0440@2|Bacteria,1N065@1224|Proteobacteria,42V6V@68525|delta/epsilon subdivisions,2WS7E@28221|Deltaproteobacteria,2MCJI@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM Amino acid-binding ACT ilvN - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5 k141_14307_2 998674.ATTE01000001_gene1809 1.92e-65 217.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales 1236|Gammaproteobacteria E TIGRFAM Acetolactate synthase, large subunit, biosynthetic ilvB GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_4155 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_2484_1 314278.NB231_05871 3.14e-16 79.0 COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1WW9G@135613|Chromatiales 135613|Chromatiales J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 k141_17112_1 1279015.KB908456_gene1679 3.23e-60 196.0 COG0583@1|root,COG0583@2|Bacteria,1R49T@1224|Proteobacteria,1SYGQ@1236|Gammaproteobacteria,1Y4P0@135624|Aeromonadales 135624|Aeromonadales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_17112_3 911045.PSE_1834 3.25e-189 537.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_19900_1 351348.Maqu_0497 1.03e-56 189.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,465QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_4613_1 1537994.JQFW01000056_gene730 9.56e-38 136.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_538_5 1288826.MSNKSG1_00521 3.84e-127 370.0 COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP synthase gamma subunit - - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k141_538_6 1288826.MSNKSG1_00516 4.29e-208 578.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,469CA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k141_538_7 1288826.MSNKSG1_00511 2.22e-278 760.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPGB@1236|Gammaproteobacteria,464X4@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_538_8 1288826.MSNKSG1_00506 6.64e-151 424.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,4665N@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k141_538_9 1288826.MSNKSG1_00501 0.0 935.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,465PV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_538_10 1288826.MSNKSG1_00496 4.42e-242 668.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,465WX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_13800_1 1444711.CCJF01000005_gene485 1.1e-14 77.0 COG2230@1|root,COG2230@2|Bacteria 2|Bacteria M cyclopropane-fatty-acyl-phospholipid synthase - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25 k141_14390_1 472759.Nhal_1097 1.68e-81 263.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1WWAD@135613|Chromatiales 135613|Chromatiales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_17232_1 1380356.JNIK01000014_gene3425 6.06e-09 62.8 COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4ETN3@85013|Frankiales 201174|Actinobacteria G Mannitol dehydrogenase Rossmann domain - - 1.1.1.57 ko:K00040 ko00040,ko01100,map00040,map01100 M00061 R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C k141_17232_2 1469245.JFBG01000075_gene167 2.15e-89 272.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1WXRI@135613|Chromatiales 135613|Chromatiales E Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 k141_9509_1 472759.Nhal_2848 3.04e-81 258.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WW0E@135613|Chromatiales 135613|Chromatiales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_2586_2 1380384.JADN01000004_gene1981 0.000199 51.2 COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia 976|Bacteroidetes T tetratricopeptide repeat batE - - - - - - - - - - - SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2 k141_18640_1 754476.Q7A_2238 8.08e-80 251.0 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,461WS@72273|Thiotrichales 72273|Thiotrichales H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,CbiA,GATase_3 k141_3969_1 1278309.KB907099_gene3092 4.05e-12 61.6 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SCXD@1236|Gammaproteobacteria,1XKP1@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k141_3969_2 1122201.AUAZ01000009_gene2836 9.25e-21 101.0 COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZS5@1236|Gammaproteobacteria,4676G@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - - - - - - - - - - GGDEF,SBP_bac_3 k141_3969_3 1278309.KB907099_gene3091 5.62e-198 553.0 COG1092@1|root,COG1092@2|Bacteria,1R6GY@1224|Proteobacteria,1RZ4H@1236|Gammaproteobacteria,1XNXK@135619|Oceanospirillales 135619|Oceanospirillales J S-adenosylmethionine-dependent methyltransferase - - - - - - - - - - - - Methyltrans_SAM k141_3969_4 1278309.KB907099_gene3090 1.5e-32 119.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,1XMGP@135619|Oceanospirillales 135619|Oceanospirillales S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_1929_1 626887.J057_09921 1.45e-90 276.0 COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RYBE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Exo_endo_phos k141_15136_1 1278309.KB907100_gene1897 1.18e-127 369.0 COG0790@1|root,COG0790@2|Bacteria,1R5EJ@1224|Proteobacteria,1SM9R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_7508_1 1333998.M2A_1243 6.52e-07 56.6 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,4BRYI@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 k141_16532_1 1288826.MSNKSG1_10433 4.49e-108 318.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRKH@1236|Gammaproteobacteria,46CYM@72275|Alteromonadaceae 1236|Gammaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GGDEF,HAMP,PAS,PAS_9 k141_19991_2 580332.Slit_0095 4.3e-15 72.4 COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,2WE7F@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 k141_12425_1 1288826.MSNKSG1_09943 2.9e-224 617.0 COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RP4C@1236|Gammaproteobacteria,464ZF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons dhmA - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 k141_12425_2 1288826.MSNKSG1_09948 1.29e-202 562.0 COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,1S37V@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_12425_3 1288826.MSNKSG1_09953 0.0 1473.0 COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae 1236|Gammaproteobacteria G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - F5_F8_type_C,GDE_C k141_12425_4 1288826.MSNKSG1_09958 6.15e-99 291.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_6069_1 861299.J421_5978 1.46e-84 261.0 COG1940@1|root,COG1940@2|Bacteria,1ZSZZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes GK ROK family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_6069_2 545264.KB898746_gene986 4.25e-21 85.5 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,1SJ46@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 k141_2587_1 335543.Sfum_3450 7.68e-31 119.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales 28221|Deltaproteobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_18641_1 1288826.MSNKSG1_15112 1.36e-147 435.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,464R6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_19367_1 314271.RB2654_07306 5.69e-143 417.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter rbsA - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_7509_1 314278.NB231_11289 1.74e-08 55.8 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_7509_2 557598.LHK_02980 4.28e-35 129.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KQT4@206351|Neisseriales 206351|Neisseriales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_6726_1 1249627.D779_3353 3.35e-07 52.4 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_6726_3 221988.MS0163 4.78e-44 147.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1Y85D@135625|Pasteurellales 135625|Pasteurellales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_5433_1 1288826.MSNKSG1_18495 0.0 1134.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 k141_10278_1 665571.STHERM_c15490 8.74e-41 142.0 2E8ZQ@1|root,33397@2|Bacteria,2J942@203691|Spirochaetes 203691|Spirochaetes - - - - - - - - - - - - - - - k141_10278_2 519989.ECTPHS_07586 4.4e-58 202.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales 135613|Chromatiales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_13801_1 318161.Sden_3293 7.72e-59 196.0 COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria,2QDMR@267890|Shewanellaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_13801_2 264730.PSPPH_0807 2.13e-52 167.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1Z7IR@136849|Pseudomonas syringae group 1236|Gammaproteobacteria T Chemotaxis protein CheY IV02_18015 - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_3342_1 321846.PS417_00345 1.47e-07 55.8 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems scoP - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_3342_2 1123368.AUIS01000035_gene79 1.66e-142 419.0 COG0843@1|root,COG0843@2|Bacteria,1QDZV@1224|Proteobacteria,1RYXY@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM cytochrome c oxidase subunit I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_8247_1 105559.Nwat_0614 3.41e-276 768.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales 135613|Chromatiales E TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_8247_2 292415.Tbd_1990 1.1e-80 243.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KRJT@119069|Hydrogenophilales 119069|Hydrogenophilales E ACT domain - - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C k141_8247_3 1255043.TVNIR_3223 2.21e-25 103.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1WWXU@135613|Chromatiales 135613|Chromatiales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_16534_1 1163617.SCD_n02058 3.49e-13 70.9 COG2199@1|root,COG3159@1|root,COG3159@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WEJC@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - DUF484,GGDEF k141_16534_2 339670.Bamb_1596 4.38e-22 98.6 COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1K1KS@119060|Burkholderiaceae 28216|Betaproteobacteria T Histidine kinase - - - ko:K14978 ko02020,map02020 M00663 - - ko00000,ko00001,ko00002,ko01001,ko02022 - - - CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_7,PAS_9,Response_reg k141_9511_1 1122194.AUHU01000007_gene309 1.36e-108 329.0 COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG2925 Exonuclease I sbcB GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 ko:K01141 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_X-T_C,RNase_T k141_539_1 1049564.TevJSym_ap00360 8.16e-176 501.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1J4EQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Aminotran_3 k141_4743_1 1278309.KB907107_gene1679 8.87e-53 182.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XHET@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC - 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_4743_2 1278309.KB907107_gene1680 3.34e-126 362.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity - - - - - - - - - - - - CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg k141_4743_3 1278309.KB907107_gene1681 1.38e-109 319.0 28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1XJCP@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126,SHOCT k141_10301_1 1183377.Py04_0726 3.57e-13 70.9 COG0477@1|root,arCOG00130@2157|Archaea,2XU3E@28890|Euryarchaeota,242P3@183968|Thermococci 183968|Thermococci G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_10301_2 94624.Bpet3615 4.27e-49 164.0 COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,2VTSP@28216|Betaproteobacteria 28216|Betaproteobacteria K Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k141_10301_3 713586.KB900536_gene2185 3.21e-128 370.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1WVUK@135613|Chromatiales 135613|Chromatiales C PFAM oxidoreductase FAD NAD(P)-binding domain protein - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k141_10301_4 1121935.AQXX01000088_gene4745 4.66e-56 181.0 COG1515@1|root,COG1515@2|Bacteria,1MYP6@1224|Proteobacteria 1224|Proteobacteria L Deoxyinosine 3'endonuclease (endonuclease V) - - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 k141_10301_5 1249627.D779_3375 7.05e-206 582.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1WVVJ@135613|Chromatiales 135613|Chromatiales F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_20003_1 391626.OAN307_c36400 1.53e-91 278.0 COG4213@1|root,COG4213@2|Bacteria,1R647@1224|Proteobacteria,2UB8M@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Periplasmic binding protein domain - - - ko:K10543 ko02010,map02010 M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.4 - - Peripla_BP_4 k141_18664_3 1245469.S58_65120 3.09e-35 125.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U7GY@28211|Alphaproteobacteria,3JYH8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NU general secretion pathway protein G gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_553_1 400668.Mmwyl1_2479 5.13e-68 216.0 COG2267@1|root,COG2267@2|Bacteria,1MWT9@1224|Proteobacteria,1SYFR@1236|Gammaproteobacteria,1XPQ6@135619|Oceanospirillales 135619|Oceanospirillales I PFAM Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_553_2 717774.Marme_2435 9.36e-85 258.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,1RYBR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct k141_11679_1 1123393.KB891316_gene1507 8.48e-31 116.0 COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,2VHKR@28216|Betaproteobacteria,1KSKE@119069|Hydrogenophilales 119069|Hydrogenophilales K WYL domain - - - - - - - - - - - - WYL k141_11679_2 292415.Tbd_2197 2.92e-196 551.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,1KRHR@119069|Hydrogenophilales 119069|Hydrogenophilales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k141_1272_1 1288826.MSNKSG1_05963 2.93e-231 657.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,464XN@72275|Alteromonadaceae 1236|Gammaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase k141_1272_2 1288826.MSNKSG1_05958 0.0 949.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,465JQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 k141_1272_3 1288826.MSNKSG1_05953 0.0 1296.0 COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1SYH1@1236|Gammaproteobacteria,46CWJ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k141_1272_4 1288826.MSNKSG1_05948 3.13e-313 852.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,46442@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_1272_5 1288826.MSNKSG1_05943 1.06e-36 135.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,469FR@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - Glyco_hydro_57 k141_17253_2 1278309.KB907099_gene2428 2.09e-52 167.0 2CECF@1|root,32RZM@2|Bacteria,1N130@1224|Proteobacteria,1S98I@1236|Gammaproteobacteria,1XM8I@135619|Oceanospirillales 135619|Oceanospirillales S pilin assembly protein - - - - - - - - - - - - - k141_17253_3 28229.ND2E_0056 4.75e-50 162.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,1S6KU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C k141_17253_4 1278309.KB907099_gene2426 3.87e-51 174.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1XIKN@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the reversible hydration of fumarate to (S)- malate fumA - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C k141_16550_1 395493.BegalDRAFT_0197 1.3e-31 122.0 COG1266@1|root,COG1266@2|Bacteria,1RCJ4@1224|Proteobacteria 1224|Proteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k141_18665_1 1123360.thalar_00344 2.83e-20 89.7 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria 28211|Alphaproteobacteria F dihydroorotase pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_18665_2 89187.ISM_09731 1.38e-51 171.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,46NF9@74030|Roseovarius 28211|Alphaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_9528_1 105559.Nwat_0822 3.71e-80 246.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1WX4R@135613|Chromatiales 135613|Chromatiales K PFAM Cyclic nucleotide-binding - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding k141_9528_2 425104.Ssed_2942 4.44e-77 243.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,2QBE7@267890|Shewanellaceae 1236|Gammaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_9528_3 1049564.TevJSym_av00170 5.04e-247 689.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1J547@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iEC042_1314.EC042_2616 tRNA-synt_1c k141_9528_4 1123276.KB893258_gene2871 2.82e-06 48.5 COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,47MT0@768503|Cytophagia 976|Bacteroidetes J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k141_21487_1 1131553.JIBI01000083_gene2408 0.000323 42.4 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,2W0MI@28216|Betaproteobacteria,372WJ@32003|Nitrosomonadales 28216|Betaproteobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_21487_2 29540.C481_00035 1.35e-58 195.0 COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,23TIB@183963|Halobacteria 183963|Halobacteria I COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_10302_1 314256.OG2516_05428 2.5e-112 341.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2PCFH@252301|Oceanicola 28211|Alphaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k141_3356_2 380394.Lferr_0741 4.77e-40 147.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2NC66@225057|Acidithiobacillales 225057|Acidithiobacillales F DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C k141_4762_1 298386.PBPRA3116 3.27e-51 165.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XY0D@135623|Vibrionales 135623|Vibrionales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein - - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_4762_2 998674.ATTE01000001_gene2787 1.17e-111 333.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales 72273|Thiotrichales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_3357_1 1278309.KB907101_gene426 6.12e-130 377.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria,1XJ2W@135619|Oceanospirillales 135619|Oceanospirillales S Catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate - - - ko:K15736 - - - - ko00000,ko01000 - - - DAO k141_18018_1 998674.ATTE01000002_gene56 9.84e-46 184.0 COG2304@1|root,COG4932@1|root,COG4935@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria,1R22X@1224|Proteobacteria,1T5FA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - SdrD_B k141_9529_1 396588.Tgr7_0082 2.01e-16 85.1 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2QR@135613|Chromatiales 135613|Chromatiales T Histidine Phosphotransfer domain - - 2.7.13.3 ko:K10715 ko02020,ko02024,map02020,map02024 M00517 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,Response_reg k141_2061_1 1168067.JAGP01000001_gene1172 3.55e-27 106.0 COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,460TG@72273|Thiotrichales 72273|Thiotrichales G HAD-superfamily subfamily IIA hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like k141_2061_2 1278309.KB907099_gene2475 0.0 1238.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XI6X@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_2061_3 1278309.KB907099_gene2476 3.03e-93 273.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1XJSV@135619|Oceanospirillales 135619|Oceanospirillales J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_2061_4 207954.MED92_02439 3.21e-31 110.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,1XM10@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the bacterial ribosomal protein bL35 family rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_2061_6 1278309.KB907099_gene2479 2.22e-229 632.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1XHW3@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d k141_2061_7 1278309.KB907099_gene2480 4.32e-133 400.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_15282_1 1026882.MAMP_01830 2.22e-13 67.8 COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,1S75J@1236|Gammaproteobacteria,462RI@72273|Thiotrichales 72273|Thiotrichales S Uncharacterized protein family, UPF0114 - - - - - - - - - - - - UPF0114 k141_15282_2 868864.Dester_0658 2.71e-17 82.0 COG1652@1|root,COG2433@1|root,COG1652@2|Bacteria,COG2433@2|Bacteria,2G4TM@200783|Aquificae 200783|Aquificae S PFAM Peptidoglycan-binding lysin domain - - - - - - - - - - - - LysM k141_6907_1 1237149.C900_04178 4.61e-69 210.0 2DS7J@1|root,33EW7@2|Bacteria,4PPYB@976|Bacteroidetes,47YSS@768503|Cytophagia 2|Bacteria - - - - - - - - - - - - - - SpoIIAA-like k141_6907_2 153721.MYP_1203 5.68e-22 89.7 COG4430@1|root,COG4430@2|Bacteria,4NQJJ@976|Bacteroidetes,47QKU@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1905) - - - - - - - - - - - - DUF1905,OmdA k141_15283_1 1005048.CFU_3735 2.21e-42 155.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,4726K@75682|Oxalobacteraceae 28216|Betaproteobacteria E Domain of unknown function (DUF3488) - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k141_11818_1 1278309.KB907101_gene716 5.31e-166 486.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XHNV@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc k141_6908_1 246197.MXAN_6603 5.02e-08 59.3 COG0727@1|root,COG0727@2|Bacteria,1N9E6@1224|Proteobacteria,438VA@68525|delta/epsilon subdivisions,2X2J7@28221|Deltaproteobacteria,2YXW8@29|Myxococcales 28221|Deltaproteobacteria S PFAM Uncharacterised protein family (UPF0153) - - - ko:K18475 - - - - ko00000,ko01000,ko02035 - - - CxxCxxCC k141_4103_1 90813.JQMT01000001_gene253 2.97e-50 159.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,4618C@72273|Thiotrichales 72273|Thiotrichales J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k141_4103_2 1168067.JAGP01000001_gene293 6.7e-56 175.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,460ZR@72273|Thiotrichales 72273|Thiotrichales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k141_20135_1 156889.Mmc1_1582 7.95e-90 276.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase - - - - - - - - - - - - Methyltransf_33 k141_20135_2 472759.Nhal_2807 2.7e-180 515.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales 135613|Chromatiales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase k141_15284_1 864073.HFRIS_013870 2.76e-95 288.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,473ZE@75682|Oxalobacteraceae 28216|Betaproteobacteria C Aldo/keto reductase family tas - - - - - - - - - - - Aldo_ket_red k141_4104_1 1101195.Meth11DRAFT_0769 3.56e-60 202.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,2KKYE@206350|Nitrosomonadales 206350|Nitrosomonadales P transporter of a GTP-driven Fe(2 ) uptake system - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k141_11819_1 522306.CAP2UW1_3606 6.64e-18 82.4 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KPWM@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Coenzyme metabolism Energy production and conversion ascD - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_11819_2 765914.ThisiDRAFT_0346 2.05e-76 242.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1WW02@135613|Chromatiales 135613|Chromatiales GM PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_11819_3 1144343.PMI41_04220 6.1e-05 47.4 2E9YS@1|root,3344A@2|Bacteria,1NKBF@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF3592) ymfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF3592 k141_15285_2 2754.EH55_10305 1.34e-15 79.0 COG0226@1|root,COG0226@2|Bacteria,3TARP@508458|Synergistetes 508458|Synergistetes P phosphate binding protein - - - - - - - - - - - - PBP_like_2 k141_6909_1 1278309.KB907111_gene3396 5.87e-27 108.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1XHX6@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_6909_2 857087.Metme_3503 1.35e-160 460.0 COG1408@1|root,COG1408@2|Bacteria,1QW5K@1224|Proteobacteria,1T3FJ@1236|Gammaproteobacteria,1XGJK@135618|Methylococcales 135618|Methylococcales S metallophosphoesterase - - - - - - - - - - - - - k141_6909_3 1177181.T9A_00468 2.78e-53 172.0 COG1463@1|root,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,1XKPV@135619|Oceanospirillales 135619|Oceanospirillales Q Protein of unknown function (DUF3465) - - - - - - - - - - - - DUF3465 k141_20138_1 272624.lpg0781 6.63e-27 99.8 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1JEYY@118969|Legionellales 118969|Legionellales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k141_6910_1 412965.COSY_0206 8.93e-36 127.0 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1SDBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_4105_1 1278309.KB907101_gene559 2.09e-37 132.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria,1XRW6@135619|Oceanospirillales 135619|Oceanospirillales NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k141_4105_2 1278309.KB907101_gene560 2.41e-128 367.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1XJ71@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_4105_3 1278309.KB907101_gene561 6.52e-129 374.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1XIE0@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_15288_1 357804.Ping_0581 7.54e-47 155.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,2QI57@267894|Psychromonadaceae 1236|Gammaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 HPPK k141_6913_1 1122137.AQXF01000006_gene754 1.98e-110 322.0 COG1802@1|root,COG1802@2|Bacteria,1MVXM@1224|Proteobacteria,2TT9E@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator GntR family - - - - - - - - - - - - FCD,GntR k141_20139_1 1134474.O59_004068 1.75e-115 368.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria N type VI secretion protein icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_11822_1 1026882.MAMP_01679 3.03e-132 398.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_11822_2 765914.ThisiDRAFT_1413 3.14e-46 154.0 COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1WY69@135613|Chromatiales 135613|Chromatiales NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_6914_2 388739.RSK20926_11684 6.77e-44 157.0 COG1846@1|root,COG3355@1|root,COG1846@2|Bacteria,COG3355@2|Bacteria,1QYSF@1224|Proteobacteria 1224|Proteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k141_11823_1 709986.Deima_2378 8.75e-37 134.0 COG1023@1|root,COG1023@2|Bacteria,1WIJ4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G NAD binding domain of 6-phosphogluconate dehydrogenase gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 k141_11823_2 396588.Tgr7_0872 4.81e-32 124.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1WX93@135613|Chromatiales 135613|Chromatiales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k141_20140_1 1288826.MSNKSG1_15052 2.66e-136 393.0 COG2807@1|root,COG2807@2|Bacteria 2|Bacteria P transmembrane transport - - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 k141_4107_1 584708.Apau_0990 3.92e-46 162.0 COG4124@1|root,COG4124@2|Bacteria,3TBYU@508458|Synergistetes 508458|Synergistetes G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k141_6915_1 314278.NB231_01968 2.11e-31 127.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1WWH5@135613|Chromatiales 135613|Chromatiales N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_15290_1 880072.Desac_0427 5.48e-33 132.0 COG0784@1|root,COG1719@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1719@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MRI2@213462|Syntrophobacterales 28221|Deltaproteobacteria T Signal transduction response regulator, receiver domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1 k141_4108_1 1157708.KB907450_gene5491 1.42e-22 102.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,4AAI8@80864|Comamonadaceae 28216|Betaproteobacteria H PFAM amine oxidase hpnE - 1.17.8.1 ko:K21677 - - - - ko00000,ko01000 - - - Amino_oxidase k141_15291_1 388413.ALPR1_19478 4.33e-61 198.0 COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,47KT4@768503|Cytophagia 976|Bacteroidetes F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase k141_15291_2 1124780.ANNU01000035_gene214 1.78e-24 100.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia 976|Bacteroidetes G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_6917_1 1208323.B30_07011 3.45e-73 232.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,2TQME@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0025 NhaP-type Na H and K H antiporters - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger k141_20142_1 1237149.C900_04595 2.66e-43 159.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia 976|Bacteroidetes M Penicillin binding protein transpeptidase pbpB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_15292_1 1122137.AQXF01000001_gene2683 8.24e-81 248.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria lpxH - - - - - - - - - - - Metallophos,Metallophos_2 k141_20143_1 1288826.MSNKSG1_01658 5.14e-88 287.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1T3BM@1236|Gammaproteobacteria,469XC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631,EAL,GGDEF k141_11824_2 1415780.JPOG01000001_gene63 3.22e-40 142.0 COG3791@1|root,COG3791@2|Bacteria,1MZTR@1224|Proteobacteria,1S5QB@1236|Gammaproteobacteria,1X8A6@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - - k141_11824_3 1121935.AQXX01000142_gene2333 3.23e-77 237.0 COG0454@1|root,COG0456@2|Bacteria,1RIAQ@1224|Proteobacteria,1T12P@1236|Gammaproteobacteria 1236|Gammaproteobacteria K FR47-like protein - - - - - - - - - - - - Acetyltransf_1 k141_6918_2 1123401.JHYQ01000025_gene3302 2.19e-59 189.0 COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,1S5W6@1236|Gammaproteobacteria,461FH@72273|Thiotrichales 72273|Thiotrichales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 k141_6918_3 1198114.AciX9_3094 1.18e-17 84.0 COG0397@1|root,COG0397@2|Bacteria 2|Bacteria S Uncharacterized ACR, YdiU/UPF0061 family MA20_28420 - - - - - - - - - - - UPF0061 k141_4109_1 391589.RGAI101_338 2.13e-227 630.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2P1ZV@2433|Roseobacter 28211|Alphaproteobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN k141_11826_1 596154.Alide2_4412 2.2e-28 118.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae 28216|Betaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin PilY1-like protein pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_20145_1 323848.Nmul_A2472 5.03e-57 191.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_15294_1 1288298.rosmuc_02805 7.78e-70 219.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2TRV8@28211|Alphaproteobacteria,46Q04@74030|Roseovarius 28211|Alphaproteobacteria E COG2113 ABC-type proline glycine betaine transport systems, periplasmic components proX - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k141_15295_1 83219.PM02_05910 1.66e-72 226.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,3ZV6T@60136|Sulfitobacter 28211|Alphaproteobacteria P Inositol monophosphatase family cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P k141_9722_1 1288826.MSNKSG1_07133 1.04e-176 505.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,465XU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k141_9722_2 1288826.MSNKSG1_07138 1.14e-251 691.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,465WP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919 NadA k141_9722_3 1288826.MSNKSG1_07143 9.22e-163 457.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,467MP@72275|Alteromonadaceae 1236|Gammaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_9722_4 1288826.MSNKSG1_07148 3.25e-111 322.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S82S@1236|Gammaproteobacteria,467EM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k141_9722_5 1288826.MSNKSG1_07153 8.98e-215 604.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,464D7@72275|Alteromonadaceae 1236|Gammaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_9722_6 1288826.MSNKSG1_07158 4.7e-79 251.0 COG3064@1|root,COG3064@2|Bacteria,1NDEI@1224|Proteobacteria,1T2B3@1236|Gammaproteobacteria,467RC@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes tolA - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_9722_7 1288826.MSNKSG1_07163 6.99e-92 270.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,4679Y@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein tolR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k141_9722_8 1288826.MSNKSG1_07168 6.06e-153 431.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,465HR@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins tolQ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB k141_9722_9 1288826.MSNKSG1_07173 5.5e-105 303.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,46841@72275|Alteromonadaceae 1236|Gammaproteobacteria S thioesterase ybgC GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790 3.1.2.23 ko:K01075,ko:K07107 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - iECP_1309.ECP_0747,iSDY_1059.SDY_0684 4HBT k141_9722_10 351348.Maqu_1704 7.02e-225 622.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,464S4@72275|Alteromonadaceae 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_9722_11 1288826.MSNKSG1_07183 5.39e-133 379.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,466RJ@72275|Alteromonadaceae 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_9722_12 1288826.MSNKSG1_07188 1.55e-63 197.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k141_11827_1 870187.Thini_2597 1.12e-44 157.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales 72273|Thiotrichales O PFAM Peptidase family M48 - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_11827_2 713586.KB900536_gene186 2.75e-29 108.0 COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SF76@1236|Gammaproteobacteria,1WZJF@135613|Chromatiales 135613|Chromatiales C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 k141_6919_1 1283300.ATXB01000001_gene1395 1.07e-98 293.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1XDVR@135618|Methylococcales 135618|Methylococcales I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_6919_2 396588.Tgr7_0947 1.98e-131 394.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1SZ84@1236|Gammaproteobacteria,1WXUW@135613|Chromatiales 135613|Chromatiales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_4111_3 1380387.JADM01000008_gene822 3.03e-22 95.1 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1XJ4H@135619|Oceanospirillales 135619|Oceanospirillales E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 k141_9723_1 398580.Dshi_1506 1.42e-111 330.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_20147_1 1382230.ASAP_2763 1.45e-19 87.0 2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_6920_1 768671.ThimaDRAFT_3775 5.81e-30 120.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales 135613|Chromatiales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k141_6920_2 686340.Metal_2004 1.16e-166 477.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XEPK@135618|Methylococcales 135618|Methylococcales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 k141_20148_2 1168065.DOK_01709 2.35e-26 110.0 COG2215@1|root,COG2215@2|Bacteria,1R3QK@1224|Proteobacteria,1SARN@1236|Gammaproteobacteria,1JB4F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the NiCoT transporter (TC 2.A.52) family - - - - - - - - - - - - DsbD_2 k141_9724_1 768671.ThimaDRAFT_2070 2.77e-30 119.0 COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,1S69P@1236|Gammaproteobacteria,1WX67@135613|Chromatiales 135613|Chromatiales K cyclic nucleotide-binding - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_15297_1 1283300.ATXB01000001_gene1089 1.34e-159 464.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XEP5@135618|Methylococcales 135618|Methylococcales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_19537_1 1278309.KB907102_gene253 3.09e-86 271.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1XIQA@135619|Oceanospirillales 135619|Oceanospirillales CH Phenol hydroxylase, C-terminal dimerisation domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_13267_1 159087.Daro_1460 1.08e-32 120.0 2DBQ4@1|root,2ZABV@2|Bacteria,1R8WU@1224|Proteobacteria,2VP1M@28216|Betaproteobacteria,2KZK8@206389|Rhodocyclales 206389|Rhodocyclales S PEP-CTERM motif - - - - - - - - - - - - VPEP k141_18946_2 768671.ThimaDRAFT_0998 3.73e-05 45.1 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_6375_1 1278309.KB907106_gene1219 4.21e-42 144.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XHWY@135619|Oceanospirillales 135619|Oceanospirillales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_6375_2 1278309.KB907106_gene1218 7.82e-147 417.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XI8X@135619|Oceanospirillales 135619|Oceanospirillales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_15485_1 580332.Slit_2478 9.38e-08 57.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,2VT8P@28216|Betaproteobacteria,44VYA@713636|Nitrosomonadales 28216|Betaproteobacteria M PFAM porin Gram-negative type - - - - - - - - - - - - Porin_4 k141_15485_2 555779.Dthio_PD3492 7.83e-12 67.8 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42SUS@68525|delta/epsilon subdivisions,2WPPP@28221|Deltaproteobacteria,2M9NR@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Sel1 domain protein repeat-containing protein - - - ko:K07126 - - - - ko00000 - - - Sel1 k141_15485_3 1049564.TevJSym_bp00150 1.04e-149 429.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1J4QF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.6,2.1.3.9 ko:K00611,ko:K09065,ko:K13252 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_14062_1 998674.ATTE01000001_gene508 1.12e-32 125.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_14062_2 1117647.M5M_12400 7.36e-12 66.6 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1J4T7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iPC815.YPO3762,iSFV_1184.SFV_3651 TrkH k141_21684_1 5017.XP_007706809.1 5.23e-21 89.7 COG3193@1|root,2SUKI@2759|Eukaryota,3A5SY@33154|Opisthokonta,3P5U5@4751|Fungi,3QXIZ@4890|Ascomycota,20508@147541|Dothideomycetes,4KIGR@92860|Pleosporales 4751|Fungi S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_21684_2 1278309.KB907108_gene1584 7.06e-300 831.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XJ0V@135619|Oceanospirillales 135619|Oceanospirillales KT PFAM sigma-54 factor interaction domain-containing protein, Activator of aromatic catabolism, helix-turn-helix Fis-type, 4-vinyl reductase 4VR - - - - - - - - - - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_21684_3 1278309.KB907108_gene1583 4.34e-106 313.0 COG0583@1|root,COG0583@2|Bacteria,1R5BA@1224|Proteobacteria,1S4S1@1236|Gammaproteobacteria,1XRND@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_2896_2 1294143.H681_01315 5.65e-09 60.1 COG0668@1|root,COG0668@2|Bacteria,1RCM8@1224|Proteobacteria,1SCM2@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel - - - - - - - - - - - - MS_channel k141_14770_1 700598.Niako_4357 1.08e-26 107.0 COG1092@1|root,COG1092@2|Bacteria,4P1C0@976|Bacteroidetes,1IVC8@117747|Sphingobacteriia 976|Bacteroidetes J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_14770_2 1485544.JQKP01000005_gene341 1.39e-96 284.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,44W6V@713636|Nitrosomonadales 28216|Betaproteobacteria H Probable molybdopterin binding domain mogA - 2.7.7.75 ko:K03831 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth k141_6376_1 582744.Msip34_1153 5.45e-94 286.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,2KKIZ@206350|Nitrosomonadales 206350|Nitrosomonadales P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_18947_1 768671.ThimaDRAFT_3994 3.23e-70 223.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1WWUA@135613|Chromatiales 135613|Chromatiales M Lytic murein transglycosylase B - - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_8479_1 1278309.KB907099_gene2702 1.64e-233 657.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XHFF@135619|Oceanospirillales 135619|Oceanospirillales T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_8479_2 1348657.M622_01530 8.36e-38 135.0 COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,2WC0K@28216|Betaproteobacteria,2KZAH@206389|Rhodocyclales 206389|Rhodocyclales L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases - - - - - - - - - - - - RNase_T k141_21082_2 1176423.I6R9Z2_9VIRU 6.9e-46 168.0 4QBN0@10239|Viruses,4R0IP@35237|dsDNA viruses no RNA stage 10239|Viruses - - - - - - - - - - - - - - - k141_21685_1 1123519.PSJM300_16225 1.3e-83 262.0 COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,1Z1PU@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria EK Transcriptional regulator of aromatic amino acids metabolism tyrR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03721 - - - - ko00000,ko03000 - - - ACT,PAS,PAS_8,Sigma54_activat k141_2897_1 395493.BegalDRAFT_0081 5.1e-49 164.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,460EX@72273|Thiotrichales 72273|Thiotrichales KO TIGRFAM Hydrogenase accessory protein HypB - - - ko:K04652 - - - - ko00000,ko03110 - - - cobW k141_2897_2 292415.Tbd_1382 1.14e-14 70.5 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VYD4@28216|Betaproteobacteria 28216|Betaproteobacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - ko:K04651 - - - - ko00000,ko03110 - - - HypA k141_14063_1 1123399.AQVE01000001_gene670 9.45e-46 166.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,460A3@72273|Thiotrichales 72273|Thiotrichales L TIGRFAM ATP-dependent DNA helicase, RecQ - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_13372_2 1122951.ATUE01000008_gene100 3.66e-40 148.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,3NJWI@468|Moraxellaceae 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_20363_1 1122137.AQXF01000002_gene156 5.78e-87 271.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_3605_1 1288826.MSNKSG1_06493 8.83e-264 728.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,4648V@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M k141_3605_2 1288826.MSNKSG1_06498 4.78e-219 604.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4649N@72275|Alteromonadaceae 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Carboxyl_trans k141_3605_3 1288826.MSNKSG1_06503 3.39e-184 513.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,463XZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k141_3605_4 1288826.MSNKSG1_06508 6.22e-123 359.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,464FS@72275|Alteromonadaceae 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_4289_1 1123392.AQWL01000010_gene2326 4.03e-70 250.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9 k141_813_1 519989.ECTPHS_03397 1.33e-50 168.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1WW0K@135613|Chromatiales 135613|Chromatiales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_813_2 305900.GV64_20335 1.23e-15 77.8 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XHIF@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_11305_1 323261.Noc_1907 8.62e-277 800.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales 135613|Chromatiales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_11978_1 1288826.MSNKSG1_08673 1.37e-44 158.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae 1236|Gammaproteobacteria GM nucleoside-diphosphate sugar epimerases wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_11978_2 1288826.MSNKSG1_08668 1.87e-79 236.0 2EE2X@1|root,337XI@2|Bacteria,1NFCM@1224|Proteobacteria,1SD53@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Transcriptional regulator - - - - - - - - - - - - Histone_HNS k141_11978_3 1288826.MSNKSG1_08663 5.69e-231 635.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,4646A@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain adrA - - - - - - - - - - - GGDEF,PAS,PAS_4 k141_11978_4 1288826.MSNKSG1_08658 1.63e-09 57.4 COG1776@1|root,COG2201@1|root,COG1776@2|Bacteria,COG2201@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,465BA@72275|Alteromonadaceae 1236|Gammaproteobacteria NT response regulator cheC - - - - - - - - - - - Response_reg k141_18948_1 225937.HP15_3301 1.96e-41 142.0 COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,1S4N1@1236|Gammaproteobacteria,46AZQ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Glutathione S-transferase gst - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 k141_7802_1 1231190.NA8A_10128 5.01e-58 206.0 COG0457@1|root,COG0846@1|root,COG0457@2|Bacteria,COG0846@2|Bacteria,1PM9Y@1224|Proteobacteria,2UZX3@28211|Alphaproteobacteria,43QKY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K SIR2-like domain - - - - - - - - - - - - SIR2_2 k141_7802_2 1453501.JELR01000001_gene2567 8.19e-59 205.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria,465ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative exonuclease SbcCD, C subunit - - - - - - - - - - - - AAA_29,SbcCD_C k141_16128_1 768671.ThimaDRAFT_0164 3e-193 550.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1WWHM@135613|Chromatiales 135613|Chromatiales Q TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_16843_1 1288826.MSNKSG1_05156 9.77e-263 723.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,464AW@72275|Alteromonadaceae 1236|Gammaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_16843_2 1288826.MSNKSG1_05151 4.93e-260 735.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_14772_1 207954.MED92_02354 2.44e-23 99.8 COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,1S90D@1236|Gammaproteobacteria,1XM2U@135619|Oceanospirillales 135619|Oceanospirillales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE k141_83_1 287.DR97_1870 2.61e-15 77.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1YDH1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k141_83_2 1121935.AQXX01000141_gene2039 5.61e-180 511.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XI4K@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA k141_83_3 525903.Taci_0717 6.96e-12 67.4 COG0745@1|root,COG0745@2|Bacteria,3TA97@508458|Synergistetes 508458|Synergistetes K Two component transcriptional regulator, winged helix family - - - ko:K07665 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_4968_1 1288826.MSNKSG1_06048 2.8e-22 92.8 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,4653C@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1131 ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_4968_2 1288826.MSNKSG1_06053 3.31e-148 419.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,465E6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0842 ABC-type multidrug transport system, permease component yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_2195_1 1278309.KB907102_gene132 2.12e-141 402.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1XHNM@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfE - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k141_2195_2 1278309.KB907102_gene133 1.79e-112 327.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1XJEJ@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind k141_12660_1 1042375.AFPL01000032_gene1018 3.02e-226 629.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,4682F@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ring hydroxylating alpha subunit (catalytic domain) yeaW GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043933,GO:0044085,GO:0048037,GO:0051259,GO:0051260,GO:0051536,GO:0051537,GO:0051540,GO:0065003,GO:0070206,GO:0070207,GO:0071840 1.14.13.239,1.14.15.7 ko:K00499,ko:K22443 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A k141_12660_2 1390370.O203_21775 5.28e-72 232.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RP59@1236|Gammaproteobacteria,1YIP0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_21083_1 1294273.roselon_02593 1.19e-16 78.2 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF2189 k141_21083_2 1188256.BASI01000003_gene2484 4.72e-92 279.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,3FCR4@34008|Rhodovulum 28211|Alphaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k141_11315_1 1288826.MSNKSG1_17670 2.27e-32 120.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_11315_2 1288826.MSNKSG1_17665 0.0 1491.0 2DBQU@1|root,2ZAGT@2|Bacteria,1R53U@1224|Proteobacteria,1RZUC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9165_1 1159870.KB907784_gene1211 4.63e-24 99.4 COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,2VMZX@28216|Betaproteobacteria,3T37P@506|Alcaligenaceae 28216|Betaproteobacteria T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C k141_9165_2 566466.NOR53_2500 7.08e-06 49.7 COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria,1T69K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT k141_20381_1 1278309.KB907103_gene1209 3.92e-132 380.0 COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,1RZJJ@1236|Gammaproteobacteria,1XHUB@135619|Oceanospirillales 135619|Oceanospirillales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 k141_17539_1 765912.Thimo_1294 6.87e-127 378.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1WW58@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF k141_15501_1 1278309.KB907099_gene2694 1.29e-171 496.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1XHJ2@135619|Oceanospirillales 135619|Oceanospirillales C Domain of unknown function (DUF3483) - - - ko:K21834 - - - - ko00000 - - - CCG,DUF3483,Fer4_8 k141_15501_2 1278309.KB907099_gene2695 2.31e-226 631.0 COG2025@1|root,COG2025@2|Bacteria,1MUQ5@1224|Proteobacteria,1RS2R@1236|Gammaproteobacteria,1XHQV@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein, alpha subunit - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_16857_2 546274.EIKCOROL_00757 5.93e-90 269.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KQG3@206351|Neisseriales 206351|Neisseriales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k141_16857_3 1229205.BUPH_06274 3.14e-22 92.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,1K03Z@119060|Burkholderiaceae 28216|Betaproteobacteria S NIF3 (NGG1p interacting factor 3) ybgI - - - - - - - - - - - NIF3 k141_10594_1 1278309.KB907111_gene3352 1.88e-221 613.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XI26@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans k141_10594_2 1278309.KB907111_gene3353 2.9e-86 256.0 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,1S970@1236|Gammaproteobacteria,1XKBV@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ - - - - - - - - - - - NUDIX k141_16858_1 314278.NB231_15853 1.83e-71 227.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1WWUA@135613|Chromatiales 135613|Chromatiales M Lytic murein transglycosylase B - - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 k141_7099_1 1219035.NT2_27_00020 2.38e-13 77.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,2K503@204457|Sphingomonadales 204457|Sphingomonadales L PFAM Transposase IS116 IS110 IS902 family, Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_14787_1 1469613.JT55_09940 9.55e-97 306.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,3FCG1@34008|Rhodovulum 28211|Alphaproteobacteria M Transglycosylase mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_1516_1 1163617.SCD_n01202 1.5e-56 191.0 COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2VJ4Z@28216|Betaproteobacteria 28216|Betaproteobacteria P TrkA-N domain protein - - - - - - - - - - - - Ion_trans_2,TrkA_N k141_1516_2 1163617.SCD_n01203 1.49e-67 206.0 2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,2VR76@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_1516_3 765912.Thimo_2164 5.93e-07 51.6 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1WXIE@135613|Chromatiales 135613|Chromatiales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF k141_18967_2 502025.Hoch_6348 3.66e-08 56.6 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_8494_2 1232683.ADIMK_0489 2.27e-26 107.0 COG4960@1|root,COG4960@2|Bacteria,1N7J0@1224|Proteobacteria,1T63E@1236|Gammaproteobacteria,46BDM@72275|Alteromonadaceae 1236|Gammaproteobacteria OU Type IV leader peptidase family - - - - - - - - - - - - Peptidase_A24 k141_8494_3 1215092.PA6_007_00010 9.9e-13 63.2 2DHPP@1|root,300HK@2|Bacteria,1Q927@1224|Proteobacteria,1TCJZ@1236|Gammaproteobacteria,1YKEE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8494_4 552398.HMPREF0866_02168 9.36e-14 77.4 COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3WSMJ@541000|Ruminococcaceae 186801|Clostridia K PFAM AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC k141_8494_5 1278309.KB907099_gene3018 5.58e-81 248.0 28IGK@1|root,2Z8I1@2|Bacteria,1RAH7@1224|Proteobacteria,1RPTY@1236|Gammaproteobacteria,1XJRN@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_3625_2 1123399.AQVE01000015_gene1813 3.37e-23 99.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,45ZU3@72273|Thiotrichales 72273|Thiotrichales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k141_16147_2 1380367.JIBC01000006_gene308 6.58e-05 47.8 2DNKU@1|root,32UJ9@2|Bacteria,1N54F@1224|Proteobacteria,2UE7X@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_17540_1 1123518.ARWI01000001_gene556 3.43e-91 276.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,45ZQP@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C k141_2917_3 1288826.MSNKSG1_06063 4.49e-165 464.0 COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,1RQIM@1236|Gammaproteobacteria,46A6G@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 k141_2917_4 1288826.MSNKSG1_06058 2.63e-110 318.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1S7AR@1236|Gammaproteobacteria,467J7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 k141_2917_5 1288826.MSNKSG1_06053 2.82e-74 227.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,465E6@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG0842 ABC-type multidrug transport system, permease component yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_9166_1 472759.Nhal_0779 6.06e-67 224.0 COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,1RQRW@1236|Gammaproteobacteria,1WWNC@135613|Chromatiales 135613|Chromatiales U Belongs to the V-ATPase 116 kDa subunit family - - - ko:K02123 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - V_ATPase_I k141_2325_2 1049564.TevJSym_bk00250 2.1e-40 142.0 COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP,YcgL k141_1683_2 187272.Mlg_2327 6.57e-196 550.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1WWW6@135613|Chromatiales 135613|Chromatiales M acid synthase - - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k141_1683_3 1177154.Y5S_03267 6.36e-58 186.0 COG1670@1|root,COG1670@2|Bacteria,1MZ2K@1224|Proteobacteria,1S9Q0@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3,Acetyltransf_4 k141_7239_1 519989.ECTPHS_01869 1.32e-114 343.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_7239_2 105559.Nwat_0227 3.31e-59 194.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_9975_1 391624.OIHEL45_04490 6.61e-73 226.0 COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria 28211|Alphaproteobacteria S rpsU-divergently transcribed protein cOQ9 - - ko:K18587 - - - - ko00000 - - - COQ9 k141_6490_1 1049564.TevJSym_ai01010 1.12e-21 94.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1J4Z3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_6490_2 317025.Tcr_1945 1.66e-37 137.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZXJ@72273|Thiotrichales 72273|Thiotrichales IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_254_1 1122599.AUGR01000002_gene3314 6.94e-136 395.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XS3F@135619|Oceanospirillales 135619|Oceanospirillales C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k141_254_2 717774.Marme_2197 3.7e-116 344.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM k141_3074_1 1380358.JADJ01000012_gene792 4.91e-81 254.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RVXM@1236|Gammaproteobacteria,1XI3N@135619|Oceanospirillales 135619|Oceanospirillales C Aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k141_7240_1 1288298.rosmuc_00152 5.04e-45 149.0 COG1846@1|root,COG1846@2|Bacteria,1RD9U@1224|Proteobacteria,2U7NF@28211|Alphaproteobacteria,46PCC@74030|Roseovarius 28211|Alphaproteobacteria K COG1846 Transcriptional regulators - - - - - - - - - - - - MarR_2 k141_7240_2 1294273.roselon_00960 2.83e-36 129.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria 28211|Alphaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 k141_5844_1 546274.EIKCOROL_00703 6.26e-07 50.8 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KPH0@206351|Neisseriales 206351|Neisseriales C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_10768_5 1288826.MSNKSG1_14067 1.72e-297 815.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1S04N@1236|Gammaproteobacteria,46AEI@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4 k141_10768_6 1288826.MSNKSG1_14072 1.35e-264 727.0 COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,1RMXR@1236|Gammaproteobacteria,46CEW@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_16282_1 768671.ThimaDRAFT_3191 2.54e-34 135.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C k141_6509_1 1278309.KB907099_gene2815 2.84e-29 112.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1S2UC@1236|Gammaproteobacteria,1XRRN@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_6509_2 1278309.KB907099_gene2814 5.09e-100 294.0 COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,1RPRS@1236|Gammaproteobacteria,1XKMU@135619|Oceanospirillales 135619|Oceanospirillales E PFAM Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE k141_6509_3 1278309.KB907099_gene2813 1.6e-120 364.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria,1XHVF@135619|Oceanospirillales 135619|Oceanospirillales CK FMN_bind - - - - - - - - - - - - FMN_bind,Fer4_5 k141_15625_1 439235.Dalk_1656 6.84e-154 441.0 COG0451@1|root,COG0451@2|Bacteria,1MW8N@1224|Proteobacteria,42NWD@68525|delta/epsilon subdivisions,2WIM8@28221|Deltaproteobacteria,2MJ2N@213118|Desulfobacterales 28221|Deltaproteobacteria GM NAD dependent epimerase/dehydratase family - - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k141_15625_2 1307759.JOMJ01000003_gene2014 2.23e-76 240.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2M9KK@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Polysaccharide biosynthesis protein - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k141_7999_1 1237149.C900_04526 7.6e-91 282.0 COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia 976|Bacteroidetes J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_4496_2 1278309.KB907106_gene1308 6.1e-127 365.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1XM9R@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_4496_3 1278309.KB907106_gene1307 8.21e-190 531.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XIWW@135619|Oceanospirillales 135619|Oceanospirillales HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 k141_4496_4 1278309.KB907106_gene1306 7.84e-110 317.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XKE3@135619|Oceanospirillales 135619|Oceanospirillales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_4496_5 1278309.KB907106_gene1305 1.88e-106 312.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1XHH5@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_12848_1 1278309.KB907109_gene3246 1.26e-109 320.0 2D1XD@1|root,32TBM@2|Bacteria,1N5MA@1224|Proteobacteria,1SC4H@1236|Gammaproteobacteria,1XKYT@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - UPF0259 k141_12848_2 1278309.KB907109_gene3247 2.06e-51 172.0 COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1XK72@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_18410_2 1415778.JQMM01000001_gene2084 3.19e-09 58.5 2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18410_3 1111728.ATYS01000048_gene3081 9.39e-08 53.1 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_0281 THF_DHG_CYH,THF_DHG_CYH_C k141_13514_1 1288826.MSNKSG1_00621 1.4e-95 288.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,46552@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Ketoacyl-synt_C,ketoacyl-synt k141_13514_2 1288826.MSNKSG1_00631 1.19e-117 337.0 COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,466RD@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF962 k141_13514_3 1288826.MSNKSG1_00636 7.32e-174 486.0 COG2207@1|root,COG2207@2|Bacteria,1N70D@1224|Proteobacteria,1S9TN@1236|Gammaproteobacteria,46924@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - HTH_18 k141_13514_4 1288826.MSNKSG1_00641 3.08e-199 555.0 COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,465CA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA - - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 k141_13514_5 1288826.MSNKSG1_00646 3.85e-76 230.0 COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1SQIV@1236|Gammaproteobacteria 1236|Gammaproteobacteria NPTU P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - - - - - - - - - - LTXXQ k141_14921_1 1288826.MSNKSG1_18190 1.09e-73 226.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,466SM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_14921_2 1288826.MSNKSG1_18195 0.0 1161.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_10769_1 1123261.AXDW01000007_gene2330 9.88e-40 141.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XCEA@135614|Xanthomonadales 135614|Xanthomonadales V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran k141_8000_1 754477.Q7C_987 1.04e-77 246.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,46007@72273|Thiotrichales 72273|Thiotrichales S DNA recombination protein RmuC - - - ko:K09760 - - - - ko00000 - - - RmuC k141_20555_2 1096930.L284_04200 0.000729 46.6 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K0SK@204457|Sphingomonadales 204457|Sphingomonadales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_8,Response_reg k141_11451_1 1288826.MSNKSG1_17436 0.0 1780.0 28S27@1|root,2ZEE0@2|Bacteria,1RAGA@1224|Proteobacteria,1S3DZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial Ig-like domain - - - - - - - - - - - - Big_5 k141_5865_1 1442599.JAAN01000020_gene2591 8.07e-54 178.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RSHU@1236|Gammaproteobacteria,1X4HC@135614|Xanthomonadales 135614|Xanthomonadales L Integrase core domain - - - - - - - - - - - - HTH_21,rve k141_5865_2 1123501.KB902311_gene33 1.7e-41 139.0 COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2UC5K@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - HTH_Tnp_1 k141_14220_1 1278309.KB907101_gene327 0.0 1153.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1XIGC@135619|Oceanospirillales 135619|Oceanospirillales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_14220_2 1278309.KB907101_gene326 1.47e-265 729.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XHUG@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_14220_3 1278309.KB907101_gene325 1.18e-101 299.0 COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,1XM5H@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_13,TetR_N k141_14220_4 1278309.KB907101_gene324 4.71e-22 94.7 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XK08@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_12849_1 1123360.thalar_00168 7.32e-49 165.0 COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Catalyzes the desulfonation of aliphatic sulfonates ssuD - 1.14.14.5 ko:K04091 ko00920,map00920 - R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 - - - Bac_luciferase k141_282_1 765912.Thimo_0613 1.54e-40 145.0 COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,1RMES@1236|Gammaproteobacteria,1WXRR@135613|Chromatiales 135613|Chromatiales H Transcriptional regulator, ModE family - - - ko:K02019 - - - - ko00000,ko03000 - - - HTH_1,TOBE k141_282_2 62928.azo3839 3.06e-92 279.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,2KU6S@206389|Rhodocyclales 206389|Rhodocyclales P Molybdenum ABC transporter periplasmic molybdate-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 k141_282_3 1026882.MAMP_02761 3.52e-120 347.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,461SD@72273|Thiotrichales 72273|Thiotrichales P Binding-protein-dependent transport system inner membrane component - - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_282_4 631362.Thi970DRAFT_00837 2.86e-93 285.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1WWTJ@135613|Chromatiales 135613|Chromatiales P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_5142_1 765910.MARPU_03160 9.04e-20 85.5 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales 135613|Chromatiales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k141_5142_2 713586.KB900536_gene1092 2.09e-226 638.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales 135613|Chromatiales J TIGRFAM ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_2350_1 247633.GP2143_14736 2.59e-43 153.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1J4PI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the GARS family purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01945,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729 GARS_A,GARS_C,GARS_N k141_17732_1 1288826.MSNKSG1_10183 7.82e-52 172.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria,46AIM@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_17732_2 1288826.MSNKSG1_10178 1.02e-111 322.0 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,1S934@1236|Gammaproteobacteria,46AMM@72275|Alteromonadaceae 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_17732_3 1288826.MSNKSG1_10173 7.07e-291 797.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RM8E@1236|Gammaproteobacteria,469IV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_21911_2 580332.Slit_2852 3.12e-44 147.0 COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,2VWEE@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_21911_3 2340.JV46_13870 1.46e-48 159.0 2DZRC@1|root,32VGV@2|Bacteria,1N2PT@1224|Proteobacteria,1SQQ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Cytochrom_C_2 k141_21911_4 870187.Thini_1596 1.59e-65 208.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,463S5@72273|Thiotrichales 72273|Thiotrichales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_7267_8 1304885.AUEY01000086_gene2459 5.65e-08 50.8 2C0WC@1|root,2ZEE6@2|Bacteria,1PACA@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_7267_9 265072.Mfla_0965 4.86e-32 121.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2VTZX@28216|Betaproteobacteria 28216|Betaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k141_10770_1 1278309.KB907099_gene2776 1.06e-65 211.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_12145_1 1278309.KB907100_gene1888 1.96e-197 561.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1XHCG@135619|Oceanospirillales 135619|Oceanospirillales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_12145_2 1278309.KB907100_gene1889 1.49e-81 246.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1XJ7H@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family (UPF0227) - - - ko:K07000 - - - - ko00000 - - - UPF0227 k141_6511_1 1163617.SCD_n02905 1.24e-53 175.0 COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2VKM6@28216|Betaproteobacteria 28216|Betaproteobacteria M Cytidylyltransferase neuA - 2.7.7.43 ko:K00983 ko00520,ko01100,map00520,map01100 - R01117,R04215 RC00152 ko00000,ko00001,ko01000 - - - CTP_transf_3 k141_21244_1 545276.KB898726_gene1046 1.7e-119 353.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1WXIP@135613|Chromatiales 135613|Chromatiales E Belongs to the agmatine deiminase family aguA - - - - - - - - - - - PAD_porph k141_21244_3 870187.Thini_0586 1.04e-15 75.9 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,463NK@72273|Thiotrichales 72273|Thiotrichales S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_19142_1 1123399.AQVE01000022_gene346 1.11e-18 88.2 COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,1RPMS@1236|Gammaproteobacteria,461WX@72273|Thiotrichales 72273|Thiotrichales M Capsule polysaccharide biosynthesis protein - - - ko:K07266 - - - - ko00000 - - - Capsule_synth k141_19142_2 553385.JEMF01000013_gene2472 6.76e-27 104.0 COG3524@1|root,COG3524@2|Bacteria,1R3ZY@1224|Proteobacteria,1RPZH@1236|Gammaproteobacteria,1XIW4@135619|Oceanospirillales 135619|Oceanospirillales M COG3524 Capsule polysaccharide export protein - - - ko:K10107 ko02010,map02010 M00249 - - ko00000,ko00001,ko00002,ko02000 3.A.1.101 - - - k141_14922_1 344747.PM8797T_02964 6.8e-70 217.0 COG2095@1|root,COG2095@2|Bacteria,2J2AQ@203682|Planctomycetes 203682|Planctomycetes U MarC family integral membrane protein - - - - - - - - - - - - MarC k141_14922_2 1094980.Mpsy_0337 8.38e-06 48.1 COG1301@1|root,arCOG04335@2157|Archaea,2XTU7@28890|Euryarchaeota,2NAEP@224756|Methanomicrobia 224756|Methanomicrobia C Sodium:dicarboxylate symporter family - - - - - - - - - - - - SDF k141_3098_1 768671.ThimaDRAFT_0195 3.19e-90 290.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WXFD@135613|Chromatiales 135613|Chromatiales P PFAM Cation - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_2351_1 1569209.BBPH01000095_gene1455 6.48e-126 367.0 COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2PV4X@265|Paracoccus 28211|Alphaproteobacteria G D-galactarate dehydratase / Altronate hydrolase, C terminus garD - 4.2.1.7,4.4.1.24 ko:K16846,ko:K16850 ko00040,ko00270,ko01100,map00040,map00270,map01100 M00631 R01540,R07633 RC00543,RC01785 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C k141_5991_2 1278309.KB907100_gene1951 1.83e-289 796.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIJV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_475_1 1121918.ARWE01000001_gene2179 9.32e-42 143.0 2ED7H@1|root,33743@2|Bacteria,1NA6E@1224|Proteobacteria,42V2U@68525|delta/epsilon subdivisions,2WS45@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_5352_1 1122137.AQXF01000001_gene3396 3.14e-24 99.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG0524 Sugar kinases, ribokinase family pfkB - 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_18565_1 1177928.TH2_01855 1.38e-51 177.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2TW2A@28211|Alphaproteobacteria,2JYUN@204441|Rhodospirillales 204441|Rhodospirillales G COG0477 Permeases of the major facilitator superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 k141_13050_1 305900.GV64_07280 2.13e-09 57.4 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,1XK02@135619|Oceanospirillales 135619|Oceanospirillales S Peptidase membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_3912_1 1168034.FH5T_02100 1.65e-99 307.0 COG3507@1|root,COG3507@2|Bacteria,4NIHD@976|Bacteroidetes,2FQIF@200643|Bacteroidia 976|Bacteroidetes G Glycosyl hydrolases family 43 - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - GH43_C,Glyco_hydro_43 k141_6676_1 1123393.KB891330_gene849 3.73e-20 86.7 2DP15@1|root,3303T@2|Bacteria,1PYYU@1224|Proteobacteria,2WE2T@28216|Betaproteobacteria,1KT3Q@119069|Hydrogenophilales 119069|Hydrogenophilales S Domain of unknown function (DUF4426) - - - - - - - - - - - - DUF4426 k141_19318_1 472759.Nhal_0521 1.55e-60 212.0 COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9 k141_14348_1 1121403.AUCV01000043_gene108 3.56e-55 192.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MPXR@213118|Desulfobacterales 28221|Deltaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_21401_1 1123355.JHYO01000034_gene563 1.66e-147 449.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,36XHA@31993|Methylocystaceae 28211|Alphaproteobacteria P AcrB/AcrD/AcrF family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran k141_21401_2 1131553.JIBI01000046_gene1599 3.08e-37 132.0 COG2010@1|root,COG2010@2|Bacteria,1NE41@1224|Proteobacteria,2WEJ6@28216|Betaproteobacteria,373D7@32003|Nitrosomonadales 28216|Betaproteobacteria C Cytochrome c, class I - - - - - - - - - - - - Cytochrome_CBB3 k141_21401_4 985665.HPL003_14305 7.35e-09 60.1 COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V0RM@1239|Firmicutes,4IPXS@91061|Bacilli,26ZIY@186822|Paenibacillaceae 91061|Bacilli KT helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 k141_10201_1 1538295.JY96_09640 4.2e-18 84.3 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,1KPD4@119065|unclassified Burkholderiales 28216|Betaproteobacteria EGP Major facilitator Superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_10201_2 396588.Tgr7_0696 2.12e-139 414.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales 135613|Chromatiales H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase k141_18566_1 225849.swp_3768 2.8e-37 127.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,2QC5X@267890|Shewanellaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_18566_2 754477.Q7C_785 1.38e-12 65.5 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,460XQ@72273|Thiotrichales 72273|Thiotrichales J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM k141_1185_1 1288826.MSNKSG1_07023 2.7e-92 283.0 COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,4654Q@72275|Alteromonadaceae 1236|Gammaproteobacteria P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) mdoD GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006109,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009889,GO:0009987,GO:0010556,GO:0010675,GO:0010962,GO:0016051,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031326,GO:0031975,GO:0032881,GO:0032885,GO:0032950,GO:0032951,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0043255,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050789,GO:0050794,GO:0051273,GO:0051274,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901576,GO:2000112 - ko:K03670 - - - - ko00000 - - - MdoG k141_1185_2 1396858.Q666_01290 1.29e-140 400.0 COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria,466TS@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1802 Transcriptional regulators prpR - - - - - - - - - - - FCD,GntR k141_1185_3 1288826.MSNKSG1_07013 2.51e-203 563.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,464GF@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407 PEP_mutase k141_1185_4 1288826.MSNKSG1_07008 4.15e-201 561.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,465RE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the citrate synthase family prpC GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630 Citrate_synt k141_1851_1 1208321.D104_13210 3.28e-12 63.9 2E4UV@1|root,32ZP8@2|Bacteria,1N4X4@1224|Proteobacteria,1SER2@1236|Gammaproteobacteria,1XQBH@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB k141_1851_2 1232683.ADIMK_0104 7.71e-188 527.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,1RYR9@1236|Gammaproteobacteria,468UK@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_1851_3 1232683.ADIMK_3457 2.16e-61 195.0 COG1802@1|root,COG1802@2|Bacteria 2|Bacteria K Transcriptional regulator csiR_1 - - ko:K15735 - - - - ko00000,ko03000 - - - FCD,GntR k141_19938_1 1469245.JFBG01000056_gene2484 1.66e-06 48.9 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1WWKN@135613|Chromatiales 135613|Chromatiales C C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - k141_19938_2 1123392.AQWL01000006_gene636 7.72e-95 301.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria 28216|Betaproteobacteria P Sulfate transporter antisigma-factor antagonist STAS - - - - - - - - - - - - STAS,Sulfate_transp k141_9440_2 713587.THITH_03835 7.67e-27 104.0 COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria 1224|Proteobacteria C COG2010 Cytochrome c, mono- and diheme variants cytC - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_17169_1 1177154.Y5S_00275 1.92e-49 171.0 28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1XHY9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_13051_1 1121943.KB899998_gene1552 1.85e-42 158.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XHBY@135619|Oceanospirillales 135619|Oceanospirillales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_12343_1 519989.ECTPHS_08783 2.14e-99 296.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k141_12343_2 1122201.AUAZ01000007_gene3598 1.13e-12 67.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,466SB@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k141_8770_1 243233.MCA3083 2.61e-70 229.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XEJ0@135618|Methylococcales 135618|Methylococcales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 k141_2520_1 1288826.MSNKSG1_03136 1.8e-129 376.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,465R6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 LpxB k141_2520_2 1288826.MSNKSG1_03131 7.58e-157 443.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,464XE@72275|Alteromonadaceae 1236|Gammaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - iPC815.YPO1056 Acetyltransf_11,Hexapep k141_2520_3 1288826.MSNKSG1_03126 1.38e-101 294.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,466WK@72275|Alteromonadaceae 1236|Gammaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - iJN746.PP_1602 FabA k141_2520_4 1288826.MSNKSG1_03121 9.3e-176 498.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,4642M@72275|Alteromonadaceae 1236|Gammaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD k141_2520_5 1288826.MSNKSG1_03116 5.94e-99 289.0 COG2825@1|root,COG2825@2|Bacteria,1N89S@1224|Proteobacteria,1SEHB@1236|Gammaproteobacteria,467JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2825 Outer membrane protein ompH - - ko:K06142 - - - - ko00000 - - - OmpH k141_2520_6 1288826.MSNKSG1_03111 2.74e-182 526.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_1186_1 123899.JPQP01000003_gene1281 4.81e-06 53.9 COG1414@1|root,COG1414@2|Bacteria,1PE7S@1224|Proteobacteria,2W892@28216|Betaproteobacteria,3T6BT@506|Alcaligenaceae 28216|Betaproteobacteria K helix_turn_helix isocitrate lyase regulation - - - - - - - - - - - - HTH_IclR,IclR k141_22059_1 1232683.ADIMK_3856 2.05e-69 221.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,464TY@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases atzB - 3.5.4.32 ko:K18456 - - - - ko00000,ko01000 - - - Amidohydro_1 k141_22059_2 1232683.ADIMK_3855 5.52e-136 389.0 COG3248@1|root,COG3248@2|Bacteria,1RC26@1224|Proteobacteria,1S3EM@1236|Gammaproteobacteria,46DI2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Nucleoside-specific channel-forming protein, Tsx - - - - - - - - - - - - Channel_Tsx,DUF5020 k141_22059_3 585502.HMPREF0645_0089 1.33e-16 86.7 COG4413@1|root,COG4413@2|Bacteria,4NHK4@976|Bacteroidetes,2FN7B@200643|Bacteroidia 976|Bacteroidetes E urea transporter - - - ko:K08717 - - - - ko00000,ko02000 1.A.28.2 - - UT k141_22059_4 342610.Patl_1160 2.3e-96 284.0 COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,2Q137@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran k141_22059_5 342610.Patl_1159 1.84e-100 295.0 COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,2Q137@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran k141_15066_1 395494.Galf_2171 7.13e-12 65.1 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,44VPA@713636|Nitrosomonadales 28216|Betaproteobacteria E PFAM aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_15066_2 243233.MCA0091 7.83e-22 95.1 COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1XFKE@135618|Methylococcales 135618|Methylococcales NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl k141_1852_1 388413.ALPR1_04183 2.21e-77 246.0 COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,47K2Z@768503|Cytophagia 976|Bacteroidetes C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_10223_2 1278309.KB907100_gene2206 5.86e-123 357.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XHIK@135619|Oceanospirillales 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_19331_1 1288826.MSNKSG1_15367 3.68e-276 758.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,46546@72275|Alteromonadaceae 1236|Gammaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0010181,GO:0015980,GO:0016020,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050662,GO:0051287,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k141_8782_1 1288826.MSNKSG1_13947 6.98e-57 179.0 COG0454@1|root,COG0456@2|Bacteria,1N538@1224|Proteobacteria,1S8WA@1236|Gammaproteobacteria,468RH@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 k141_8782_2 1288826.MSNKSG1_13942 1.23e-175 490.0 COG0834@1|root,COG0834@2|Bacteria,1MXME@1224|Proteobacteria,1RPQ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET Belongs to the bacterial solute-binding protein 3 family - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_8782_3 1288826.MSNKSG1_13937 9.76e-71 224.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,469PM@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_10951_1 1218075.BAYA01000029_gene5823 9.58e-27 107.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,1K3CA@119060|Burkholderiaceae 28216|Betaproteobacteria N With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_9460_1 1288826.MSNKSG1_05211 1.36e-79 245.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,4673V@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_9460_2 1288826.MSNKSG1_05206 6.62e-251 730.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,4645X@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_2545_1 1026882.MAMP_01949 9.24e-114 354.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales 72273|Thiotrichales E TIGRFAM aminopeptidase N, Escherichia coli type pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k141_8197_2 1278309.KB907105_gene1543 2.04e-112 330.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1XREM@135619|Oceanospirillales 135619|Oceanospirillales NU Tetratricopeptide repeat - - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_8 k141_8197_3 1278309.KB907105_gene1542 2.11e-256 705.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1XI0U@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_19959_2 1278309.KB907099_gene3031 4.79e-47 154.0 COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,1XK46@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_22074_1 319224.Sputcn32_0424 1.14e-80 244.0 COG1396@1|root,COG1396@2|Bacteria,1R4NU@1224|Proteobacteria,1RQG0@1236|Gammaproteobacteria,2QAVT@267890|Shewanellaceae 1236|Gammaproteobacteria K Helix-turn-helix XRE-family like proteins ydcN GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - Cupin_2,HTH_3 k141_22074_2 349521.HCH_04789 1.67e-36 124.0 COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria,1XM1J@135619|Oceanospirillales 135619|Oceanospirillales S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin k141_11622_1 1237149.C900_00749 9.59e-41 150.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40 k141_6006_1 748658.KB907313_gene2363 3.06e-105 332.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X2AG@135613|Chromatiales 135613|Chromatiales T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc,PilZ k141_3923_1 292415.Tbd_2380 1.64e-64 205.0 COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria 28216|Betaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_4687_1 1278309.KB907103_gene1050 3.29e-92 277.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XK1Y@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein UspA and related nucleotide-binding ydaA - - ko:K14055 - - - - ko00000 - - - Usp k141_4687_2 1278309.KB907103_gene1049 1.2e-74 225.0 COG0607@1|root,30IDD@2|Bacteria,1PEG3@1224|Proteobacteria,1RUXR@1236|Gammaproteobacteria,1XK5A@135619|Oceanospirillales 135619|Oceanospirillales P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 k141_4687_3 1278309.KB907103_gene1048 2.75e-220 617.0 COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,1RZUV@1236|Gammaproteobacteria,1XJ57@135619|Oceanospirillales 135619|Oceanospirillales T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_7460_1 1117647.M5M_04385 6.94e-09 64.3 COG1652@1|root,COG1652@2|Bacteria,1R2E7@1224|Proteobacteria,1T5NN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S haemagglutination activity domain - - - - - - - - - - - - Haemagg_act,LysM k141_7460_2 754476.Q7A_1224 2.17e-68 211.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_7460_4 1384056.N787_06005 1.49e-51 166.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1X6WU@135614|Xanthomonadales 135614|Xanthomonadales P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_1208_1 290398.Csal_3149 3.48e-13 65.9 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1XM1T@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF423 k141_1208_2 1278309.KB907100_gene2150 2.13e-30 108.0 COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1XM0J@135619|Oceanospirillales 135619|Oceanospirillales H ThiS family - - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_18584_1 876044.IMCC3088_662 1.05e-29 116.0 COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria,1J7KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_18584_2 314285.KT71_07724 8.68e-107 320.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RS5B@1236|Gammaproteobacteria,1JBSV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ghrB_1 - 1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81 ko:K00032,ko:K00050,ko:K00090 ko00030,ko00260,ko00480,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00480,map00620,map00630,map01100,map01110,map01120 - R00465,R01388,R01392,R01739,R02032,R02034 RC00001,RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_18584_3 351348.Maqu_2344 2.2e-114 343.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,464WN@72275|Alteromonadaceae 1236|Gammaproteobacteria C FMN-dependent dehydrogenase lldD - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh k141_8198_1 1123401.JHYQ01000002_gene2785 6.13e-47 163.0 COG0547@1|root,COG0547@2|Bacteria,1PI4H@1224|Proteobacteria,1T9UI@1236|Gammaproteobacteria,4623U@72273|Thiotrichales 72273|Thiotrichales E PFAM Glycosyl transferase family, a b domain - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_5378_1 1278309.KB907104_gene885 5.6e-198 552.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XI08@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_3304_1 1248232.BANQ01000056_gene2966 2.29e-29 113.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1XTG2@135623|Vibrionales 135623|Vibrionales S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 k141_3304_2 1200567.JNKD01000010_gene560 3e-07 55.1 COG2270@1|root,COG2270@2|Bacteria,1QUVA@1224|Proteobacteria,1T226@1236|Gammaproteobacteria,1Y6PV@135624|Aeromonadales 135624|Aeromonadales S Acetyl-coenzyme A transporter 1 - - - - - - - - - - - - MFS_1 k141_17933_1 981223.AIED01000003_gene2584 5.02e-33 127.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,3NJWT@468|Moraxellaceae 1236|Gammaproteobacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1596,iSDY_1059.SDY_0191 CTP_transf_1 k141_15088_1 1278307.KB906967_gene2571 5.15e-73 229.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,2QHSE@267894|Psychromonadaceae 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB2 - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_14354_1 1283300.ATXB01000001_gene1649 1.11e-09 57.8 COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,1S75J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein family, UPF0114 - - - - - - - - - - - - UPF0114 k141_14354_2 1049564.TevJSym_af00770 4.43e-59 187.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,1J72M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins resA - - - - - - - - - - - AhpC-TSA k141_14354_3 768671.ThimaDRAFT_3901 5.15e-43 147.0 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_9612_3 314285.KT71_07269 1.8e-31 118.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,1JAGV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_10385_1 211165.AJLN01000100_gene4105 4.86e-92 276.0 COG1028@1|root,COG1028@2|Bacteria,1G4KK@1117|Cyanobacteria 1117|Cyanobacteria IQ Short chain dehydrogenase - - - - - - - - - - - - adh_short_C2 k141_10385_2 1278309.KB907101_gene737 1.33e-258 718.0 COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,1RPFC@1236|Gammaproteobacteria,1XKJ0@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1 k141_10408_1 1288826.MSNKSG1_10308 1.83e-42 147.0 28Z9U@1|root,2ZM1P@2|Bacteria,1RBFF@1224|Proteobacteria,1S17A@1236|Gammaproteobacteria,4676U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12540_1 1121106.JQKB01000020_gene2041 1.53e-24 94.7 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,2JSQZ@204441|Rhodospirillales 204441|Rhodospirillales O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k141_12540_2 1279009.ADICEAN_03316 8.52e-11 65.5 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k141_20804_1 326298.Suden_0736 3.44e-94 291.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNN1@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria P Sulfate permease - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_22242_2 990073.ATHU01000001_gene1464 4.25e-22 100.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,NIT,Response_reg k141_6179_1 1288826.MSNKSG1_00191 5.49e-74 236.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,464AB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k141_6179_2 765911.Thivi_2307 5.9e-16 76.6 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1WW2I@135613|Chromatiales 135613|Chromatiales HL Thiamine monophosphate synthase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,NUDIX_4,TMP-TENI k141_8949_2 857087.Metme_3218 1.23e-71 227.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_5531_1 1177181.T9A_00450 4.31e-37 135.0 COG0697@1|root,COG0697@2|Bacteria,1R7CG@1224|Proteobacteria,1S0XU@1236|Gammaproteobacteria,1XJ96@135619|Oceanospirillales 135619|Oceanospirillales EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_10409_1 983544.Lacal_0869 6.61e-17 85.5 COG0784@1|root,COG1352@1|root,COG2201@1|root,COG4372@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4372@2|Bacteria,COG5002@2|Bacteria,4PKNJ@976|Bacteroidetes,1IJIK@117743|Flavobacteriia 976|Bacteroidetes T protein-glutamate methylesterase - - 2.1.1.80,3.1.1.61 ko:K00575,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg k141_16638_1 631362.Thi970DRAFT_03563 3.66e-31 115.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1WXYX@135613|Chromatiales 135613|Chromatiales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_16638_2 1444770.AF72_05240 8.69e-08 50.8 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1X871@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 k141_629_1 1123401.JHYQ01000016_gene2987 1.23e-169 478.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,4606J@72273|Thiotrichales 72273|Thiotrichales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas k141_21568_1 338963.Pcar_0534 4.29e-23 103.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k141_12541_1 765911.Thivi_4252 2.51e-51 176.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1WWKU@135613|Chromatiales 135613|Chromatiales M Sugar transferase, PEP-CTERM EpsH1 system associated - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 k141_6797_1 1122201.AUAZ01000037_gene3847 2.75e-118 356.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,468GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_4843_1 1238190.AMQY01000014_gene976 2.85e-113 335.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XII3@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_15194_1 911045.PSE_3991 6.31e-63 202.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA k141_15194_2 765914.ThisiDRAFT_1060 3.95e-29 114.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales 135613|Chromatiales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k141_11125_2 1469613.JT55_04950 9.7e-122 356.0 COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria,3FDVN@34008|Rhodovulum 28211|Alphaproteobacteria E COG0685 5,10-methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR k141_16639_1 1268068.PG5_55510 6.47e-131 384.0 COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,1RNNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C FAD linked oxidase domain protein - - 1.17.99.1 ko:K05797 ko00623,ko01100,ko01120,map00623,map01100,map01120 - R02675,R11194 RC00769 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_13914_2 1278309.KB907102_gene27 6.24e-176 494.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XIYJ@135619|Oceanospirillales 135619|Oceanospirillales M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_17340_1 1288826.MSNKSG1_16886 8.87e-121 350.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,46677@72275|Alteromonadaceae 1236|Gammaproteobacteria EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_17340_2 1288826.MSNKSG1_16881 1.39e-234 647.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,465P1@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k141_17340_3 1288826.MSNKSG1_16876 2.04e-154 445.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,465MM@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_7587_1 395493.BegalDRAFT_2440 4.62e-18 80.5 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_15998_1 1499686.BN1079_02586 4.3e-59 196.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_15998_2 287.DR97_2951 3.05e-83 258.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1YDYY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k141_13230_1 1444770.AF72_05280 6.15e-30 119.0 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1S23W@1236|Gammaproteobacteria,1X4E3@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria rpfE - - - - - - - - - - - - k141_630_1 870187.Thini_3100 4.11e-25 106.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,460Z9@72273|Thiotrichales 72273|Thiotrichales P PFAM TonB-dependent Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_5532_1 857087.Metme_1483 2.16e-46 156.0 COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1XFDF@135618|Methylococcales 135618|Methylococcales O Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_5532_2 1282362.AEAC466_13275 1.08e-19 89.4 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2TT6V@28211|Alphaproteobacteria,2KHKK@204458|Caulobacterales 204458|Caulobacterales P Voltage gated chloride channel - - - - - - - - - - - - Voltage_CLC k141_4844_1 1278309.KB907099_gene3129 0.000836 39.7 2DZDS@1|root,32V82@2|Bacteria,1N6EX@1224|Proteobacteria,1S9VE@1236|Gammaproteobacteria,1XKPN@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_4844_2 1278309.KB907099_gene3130 2.99e-44 145.0 2DZDS@1|root,32V82@2|Bacteria,1N6EX@1224|Proteobacteria,1S9VE@1236|Gammaproteobacteria,1XKPN@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_12542_1 999141.GME_13375 1.46e-18 79.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1XJN8@135619|Oceanospirillales 135619|Oceanospirillales J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_12542_2 948565.AFFP02000005_gene411 2.22e-69 213.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1Y85D@135625|Pasteurellales 135625|Pasteurellales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k141_10410_1 472759.Nhal_0313 4.19e-40 146.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1WX07@135613|Chromatiales 135613|Chromatiales M PFAM Cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_10410_2 522373.Smlt2372 6.25e-42 147.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1X449@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_2697_1 1278309.KB907100_gene2269 9.78e-111 325.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XIP5@135619|Oceanospirillales 135619|Oceanospirillales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k141_2697_2 1278309.KB907100_gene2268 2.82e-103 300.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1XJJN@135619|Oceanospirillales 135619|Oceanospirillales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_2697_3 1278309.KB907100_gene2267 7.8e-155 441.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1XIPZ@135619|Oceanospirillales 135619|Oceanospirillales S protein containing LysM domain - - - - - - - - - - - - LysM k141_6798_1 1150469.RSPPHO_03226 5.19e-06 46.6 2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,2UD5X@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_21569_1 1049564.TevJSym_am00320 3.1e-57 191.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1J9H8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E FAD dependent oxidoreductase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k141_11126_1 1167006.UWK_01458 5.59e-13 68.9 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MPYE@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM Transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_14506_2 316275.VSAL_II0670 1.88e-90 280.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,1XSPY@135623|Vibrionales 135623|Vibrionales S GTPases (G3E family) - - - - - - - - - - - - cobW k141_6180_1 223926.28809511 1.76e-100 304.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XW26@135623|Vibrionales 135623|Vibrionales S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb k141_6180_2 1056512.D515_00994 2.68e-47 162.0 COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,1SI75@1236|Gammaproteobacteria,1XWMS@135623|Vibrionales 135623|Vibrionales C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C k141_13231_2 713586.KB900536_gene672 9.57e-39 141.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria,1X2EF@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 k141_1373_1 1121035.AUCH01000003_gene1217 2.44e-49 181.0 COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,2VNMU@28216|Betaproteobacteria,2KUK5@206389|Rhodocyclales 206389|Rhodocyclales L PALM domain, HD hydrolase domain and - - - ko:K09749 - - - - ko00000 - - - FapA k141_1373_2 713586.KB900536_gene98 1.84e-65 210.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1WW4Q@135613|Chromatiales 135613|Chromatiales CH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_13915_1 396588.Tgr7_3149 1.38e-70 230.0 COG2199@1|root,COG3706@2|Bacteria,1R59V@1224|Proteobacteria,1S4YK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg k141_9634_1 420324.KI911956_gene3392 1.38e-99 305.0 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,2TRR9@28211|Alphaproteobacteria,1JR6J@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k141_9634_2 472759.Nhal_3683 8.71e-170 480.0 COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,1WZWK@135613|Chromatiales 135613|Chromatiales G pfkB family carbohydrate kinase - - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_9634_3 498211.CJA_2206 9.39e-33 117.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1FHDS@10|Cellvibrio 1236|Gammaproteobacteria M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_12543_1 1121396.KB893095_gene4377 6.11e-99 301.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM,DctQ k141_20026_1 1288826.MSNKSG1_02654 5.89e-169 493.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,464S9@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind k141_20026_2 1288826.MSNKSG1_02649 1.16e-238 656.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,465BM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d k141_20026_3 1288826.MSNKSG1_02644 5.47e-72 217.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,466ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k141_20026_4 1288826.MSNKSG1_02639 1.08e-33 116.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,468CG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_20026_5 1479237.JMLY01000001_gene1735 6.8e-66 201.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,466GC@72275|Alteromonadaceae 1236|Gammaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k141_20026_6 1288826.MSNKSG1_02629 0.0 1292.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,464IQ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD k141_20026_7 1288826.MSNKSG1_02624 0.0 1638.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,469RS@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, fused permease components - - - - - - - - - - - - DUF3394,DctM k141_20026_8 1288826.MSNKSG1_02619 1.02e-229 633.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,4656X@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, periplasmic component - - - ko:K07080 - - - - ko00000 - - - NMT1_3 k141_20026_9 1288826.MSNKSG1_02614 0.0 1518.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,464A0@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporters of the RND superfamily IV02_10640 - - ko:K07003 - - - - ko00000 - - - MMPL k141_20026_10 1288826.MSNKSG1_02609 5.28e-219 609.0 COG4447@1|root,COG4447@2|Bacteria,1R3TI@1224|Proteobacteria,1SZVS@1236|Gammaproteobacteria,467MA@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - PSII_BNR k141_20026_11 1288826.MSNKSG1_02604 1.53e-277 761.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,464MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_3453_1 1278309.KB907109_gene3254 2.42e-160 461.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XHIH@135619|Oceanospirillales 135619|Oceanospirillales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k141_3453_2 1278309.KB907109_gene3253 7.75e-88 261.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1XJZ1@135619|Oceanospirillales 135619|Oceanospirillales H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_3453_3 1278309.KB907109_gene3252 4.55e-172 482.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1XH37@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k141_3453_4 1278309.KB907109_gene3251 1.34e-85 258.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1XHBC@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_13232_1 472759.Nhal_0146 4.57e-94 290.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales 135613|Chromatiales K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_22243_1 1123518.ARWI01000001_gene1826 2.05e-96 322.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,MHYT,PAS_3,PAS_4,PAS_9 k141_15999_2 1453501.JELR01000001_gene1901 2.86e-19 92.8 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP k141_11127_2 640081.Dsui_2378 9.3e-23 91.7 2C84F@1|root,334ZR@2|Bacteria,1N6VS@1224|Proteobacteria,2VWHA@28216|Betaproteobacteria,2KXJN@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_11127_3 1298593.TOL_1925 1.67e-26 103.0 2BV15@1|root,32QDR@2|Bacteria,1RJ98@1224|Proteobacteria,1RYP4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_17342_1 998674.ATTE01000001_gene2787 1.09e-74 235.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales 72273|Thiotrichales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_2698_1 377629.TERTU_1649 9.12e-60 204.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,2PPC4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria O C-terminal, D2-small domain, of ClpB protein clpV - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_20805_1 1198232.CYCME_0743 3.57e-263 723.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales 72273|Thiotrichales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_1374_1 247639.MGP2080_08049 1.54e-06 50.1 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_1374_2 1049564.TevJSym_ap00800 6.91e-87 264.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1J4RX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 ACCA k141_4869_2 1380358.JADJ01000012_gene794 4.24e-116 345.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E oxidoreductase - - - - - - - - - - - - DAO k141_20818_1 349521.HCH_02263 1.78e-32 114.0 2E32V@1|root,32Y33@2|Bacteria,1N9B0@1224|Proteobacteria,1SCHJ@1236|Gammaproteobacteria,1XM0A@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20818_3 349521.HCH_05438 6.81e-82 245.0 COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,1S3YJ@1236|Gammaproteobacteria,1XRX2@135619|Oceanospirillales 135619|Oceanospirillales K Acetyltransferase (GNAT) domain - - 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_20818_4 1547437.LL06_24715 9.03e-83 260.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,2TT69@28211|Alphaproteobacteria,43IE3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO k141_3477_1 351348.Maqu_3619 4.01e-83 257.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,46469@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese k141_6202_1 1121439.dsat_0351 2.77e-25 99.4 2EQ8H@1|root,33HUS@2|Bacteria,1P3BS@1224|Proteobacteria,431XZ@68525|delta/epsilon subdivisions,2WWAX@28221|Deltaproteobacteria,2MCNS@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_6202_2 265072.Mfla_2628 5.69e-104 336.0 COG0715@1|root,COG2202@1|root,COG5001@1|root,COG0715@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales 206350|Nitrosomonadales T PFAM EAL domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,NMT1,PAS_3,PAS_9 k141_4870_1 686340.Metal_0661 1.89e-11 62.8 COG2265@1|root,COG2265@2|Bacteria,1QV4X@1224|Proteobacteria,1S273@1236|Gammaproteobacteria,1XFHH@135618|Methylococcales 135618|Methylococcales J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k141_11940_2 1278309.KB907107_gene1755 1.77e-101 300.0 COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA k141_11940_3 1278309.KB907107_gene1754 3.47e-60 192.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XHJD@135619|Oceanospirillales 135619|Oceanospirillales T Two component signalling adaptor domain - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_15440_1 857087.Metme_3976 1.49e-06 49.3 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1S4DQ@1236|Gammaproteobacteria,1XGEI@135618|Methylococcales 135618|Methylococcales NT SMART CheW-like protein - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_15440_2 55601.VANGNB10_cI1407c 4.64e-15 78.6 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XWA0@135623|Vibrionales 135623|Vibrionales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_7044_1 1288826.MSNKSG1_06113 9.01e-129 367.0 COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,1S1F0@1236|Gammaproteobacteria,467F2@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k141_20317_1 1177928.TH2_12342 3.81e-62 200.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JQQC@204441|Rhodospirillales 204441|Rhodospirillales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - - - - - - - - - - ABC_tran,TOBE_2 k141_20317_2 1122214.AQWH01000002_gene4394 3.16e-10 60.5 COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TRJ3@28211|Alphaproteobacteria,2PKQW@255475|Aurantimonadaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 k141_18201_1 765911.Thivi_2706 7.42e-55 197.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg k141_63_1 283699.D172_4140 1.46e-51 187.0 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,2Q1HB@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N k141_15441_1 498761.HM1_1945 3.36e-71 229.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia 186801|Clostridia H Belongs to the UbiD family - - 4.1.1.61,4.1.1.98 ko:K03182,ko:K16239 ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120 M00117 R01238,R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k141_1467_1 1089552.KI911559_gene616 8.7e-44 161.0 2F2Q4@1|root,33VKG@2|Bacteria,1NWD0@1224|Proteobacteria,2USFD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_18202_1 323261.Noc_2631 8.2e-54 179.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_14030_1 243159.AFE_2447 1.22e-06 48.5 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1S73Y@1236|Gammaproteobacteria,2NDSR@225057|Acidithiobacillales 225057|Acidithiobacillales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_20318_1 207954.MED92_04147 1.44e-32 130.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XIW5@135619|Oceanospirillales 135619|Oceanospirillales NU Tfp pilus assembly protein - - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_13343_1 313606.M23134_05183 0.000159 46.6 2AFVR@1|root,315YE@2|Bacteria,4PK8B@976|Bacteroidetes,47SSJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_13343_2 1047013.AQSP01000126_gene2739 2.45e-29 117.0 COG3525@1|root,COG3525@2|Bacteria,2NNQC@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolase family 20, catalytic domain - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b k141_21039_1 1185876.BN8_01275 1.72e-81 261.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_10539_1 1123399.AQVE01000020_gene1700 6.2e-115 355.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales 72273|Thiotrichales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k141_9825_1 1396858.Q666_10895 4.92e-82 252.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,464DG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_9825_2 1288826.MSNKSG1_04941 1.87e-151 432.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,464VM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_2860_1 857087.Metme_3218 7.89e-88 270.0 COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family - - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_9137_1 667632.KB890178_gene27 3.73e-20 92.4 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,1K2NX@119060|Burkholderiaceae 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 k141_5687_1 377629.TERTU_2471 1.64e-43 151.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,2PMZK@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D Segregation and condensation protein ScpA scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k141_16102_2 765913.ThidrDRAFT_3402 4.65e-89 269.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1WWW9@135613|Chromatiales 135613|Chromatiales L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt - - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T k141_20319_1 981384.AEYW01000021_gene3419 8.63e-111 334.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,4N9WW@97050|Ruegeria 28211|Alphaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k141_12630_2 999549.KI421513_gene3063 8.17e-83 269.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,280XH@191028|Leisingera 28211|Alphaproteobacteria M Penicillin-binding protein OB-like domain mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_14031_2 349124.Hhal_1843 3.85e-24 94.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_21040_1 1279019.ARQK01000033_gene1080 1.04e-36 136.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1WW6B@135613|Chromatiales 135613|Chromatiales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_21040_2 686340.Metal_3501 6.77e-56 184.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1XDKM@135618|Methylococcales 135618|Methylococcales M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k141_2159_1 472759.Nhal_3606 1.68e-14 73.2 2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1WZUU@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2802) - - - - - - - - - - - - DUF2802 k141_3570_2 697282.Mettu_1037 4.19e-26 97.1 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1XFSG@135618|Methylococcales 135618|Methylococcales S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p k141_18204_1 1288826.MSNKSG1_04701 3.41e-143 407.0 COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,46451@72275|Alteromonadaceae 1236|Gammaproteobacteria DT COG1718 Serine threonine protein kinase involved in cell cycle control IV02_22125 - 2.7.11.1 ko:K07178 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko01001,ko03009 - - - RIO1 k141_16826_1 999141.GME_02194 8.81e-37 127.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XK38@135619|Oceanospirillales 135619|Oceanospirillales FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hinT - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_1477_1 1472418.BBJC01000001_gene834 5.7e-30 119.0 COG1178@1|root,COG3840@1|root,COG1178@2|Bacteria,COG3840@2|Bacteria,1MWCF@1224|Proteobacteria,2TQKC@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1178 ABC-type Fe3 transport system permease component thiP - - ko:K02063 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - - BPD_transp_1 k141_1477_2 391595.RLO149_c040410 3.16e-103 305.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2P11J@2433|Roseobacter 28211|Alphaproteobacteria C COG2857 Cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_4950_1 713586.KB900536_gene2631 2.86e-59 186.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1WYSF@135613|Chromatiales 135613|Chromatiales P PFAM ApaG domain protein apaG - - ko:K06195 - - - - ko00000 - - - DUF525 k141_4950_2 395493.BegalDRAFT_1171 1.5e-09 57.8 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,1SE7Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_8456_1 317025.Tcr_1030 1.24e-87 263.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,45ZSP@72273|Thiotrichales 72273|Thiotrichales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_12647_1 713586.KB900536_gene89 5.59e-53 189.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales 135613|Chromatiales T PFAM EAL domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k141_13363_1 1175306.GWL_19210 5.69e-67 228.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2VHM3@28216|Betaproteobacteria,4756U@75682|Oxalobacteraceae 28216|Betaproteobacteria I Phospholipase D Active site motif - - 3.1.4.4 ko:K01115 ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231 - R01310,R02051,R07385 RC00017,RC00425 ko00000,ko00001,ko01000,ko04131 - - - PLDc,PLDc_2,SNARE_assoc k141_4263_1 1288826.MSNKSG1_11023 4.39e-07 52.0 COG1800@1|root,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - k141_4263_2 1288826.MSNKSG1_11028 7.72e-122 349.0 COG2197@1|root,COG2197@2|Bacteria,1N13M@1224|Proteobacteria,1SBU0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg k141_17495_1 225937.HP15_1806 2.58e-41 153.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,464A9@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_17495_2 557598.LHK_01100 1.2e-71 233.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,2KPS5@206351|Neisseriales 206351|Neisseriales P phosphonate C-P lyase system protein PhnK - - - ko:K13896 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k141_7059_1 536019.Mesop_5079 1.36e-63 214.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,43IWD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria EGP Major facilitator superfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_9839_1 1278309.KB907099_gene2389 1.58e-44 150.0 COG3117@1|root,COG3117@2|Bacteria,1N7VT@1224|Proteobacteria,1SD7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Lipopolysaccharide-assembly, LptC-related - - - - - - - - - - - - LptC k141_9839_2 1278309.KB907099_gene2388 7.86e-87 260.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1XMAP@135619|Oceanospirillales 135619|Oceanospirillales S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA k141_9839_3 207954.MED92_01589 1.24e-17 79.3 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XI7T@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter ATP-binding protein lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_19599_1 697282.Mettu_0422 1.91e-147 430.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XDTS@135618|Methylococcales 135618|Methylococcales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e k141_15467_1 1123073.KB899241_gene2017 6.06e-146 420.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1X580@135614|Xanthomonadales 135614|Xanthomonadales S ATPase (AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_2877_1 1283300.ATXB01000001_gene911 1.02e-16 84.3 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1XEN6@135618|Methylococcales 135618|Methylococcales T HDOD domain - - - - - - - - - - - - HDOD k141_7783_1 713586.KB900536_gene1527 1.42e-58 196.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amino Acid - - - - - - - - - - - - AA_permease_2 k141_7783_2 1123368.AUIS01000025_gene1489 1.04e-145 439.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RZ20@1236|Gammaproteobacteria,2NE5G@225057|Acidithiobacillales 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - EAL,GGDEF k141_7783_3 472759.Nhal_0232 8.59e-96 294.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WWMQ@135613|Chromatiales 135613|Chromatiales C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_21671_2 631362.Thi970DRAFT_03309 6.67e-163 459.0 COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T3U6@1236|Gammaproteobacteria,1X2Q2@135613|Chromatiales 135613|Chromatiales H Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family - - 2.1.1.156 ko:K18896 ko00260,map00260 - R10060 RC00003,RC03038 ko00000,ko00001,ko01000 - - - Methyltransf_25 k141_21671_3 405948.SACE_3901 8.28e-44 156.0 COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,2IAU4@201174|Actinobacteria,4E21M@85010|Pseudonocardiales 201174|Actinobacteria MQ PFAM Methyltransferase domain - - 2.1.1.156,2.1.1.157 ko:K18896,ko:K18897 ko00260,map00260 - R10060,R10061 RC00003,RC03038,RC03040 ko00000,ko00001,ko01000 - - - Methyltransf_11,Methyltransf_25 k141_16827_1 396588.Tgr7_2915 1.77e-115 338.0 COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria,1X286@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind k141_11282_1 1278309.KB907102_gene275 2.75e-100 310.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XIWM@135619|Oceanospirillales 135619|Oceanospirillales L DNA helicase recQ1 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_16110_1 118163.Ple7327_3451 1.6e-36 125.0 COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria,3VMXP@52604|Pleurocapsales 1117|Cyanobacteria S enzyme of the cupin superfamily - - - ko:K06995 - - - - ko00000 - - - Cupin_3 k141_16110_2 1454004.AW11_01265 7.46e-50 171.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2VPFR@28216|Betaproteobacteria 28216|Betaproteobacteria P Citrate transporter - - - - - - - - - - - - CitMHS k141_20341_2 998088.B565_0043 3.45e-42 149.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1Y4XV@135624|Aeromonadales 135624|Aeromonadales S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_14046_1 1121405.dsmv_1436 1.06e-130 387.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2WJF1@28221|Deltaproteobacteria,2MJ0Z@213118|Desulfobacterales 28221|Deltaproteobacteria F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k141_4951_1 1122164.JHWF01000025_gene85 3.98e-05 47.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1JC8N@118969|Legionellales 118969|Legionellales E Bacterial NAD-glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_1478_1 1121861.KB899916_gene1764 1.27e-57 198.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TTAY@28211|Alphaproteobacteria,2JW39@204441|Rhodospirillales 204441|Rhodospirillales C Molybdopterin oxidoreductase Fe4S4 domain - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_8457_1 1288826.MSNKSG1_05973 2.39e-179 513.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0514 Superfamily II DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k141_18920_2 1288826.MSNKSG1_04726 3.47e-206 574.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria,469RX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Alcohol dehydrogenase GroES-like domain - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 k141_17496_1 1082932.ATCR1_06746 2.99e-17 87.4 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,4BCZZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k141_3586_1 870187.Thini_1582 3.9e-61 200.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,45ZR9@72273|Thiotrichales 72273|Thiotrichales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_3586_2 1122194.AUHU01000014_gene1147 6.29e-72 229.0 COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - - k141_15468_1 1026882.MAMP_02023 2.48e-36 135.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,460HT@72273|Thiotrichales 72273|Thiotrichales G Belongs to the glucose-6-phosphate 1-epimerase family - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_11283_1 743299.Acife_1385 3.12e-23 99.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,2NC39@225057|Acidithiobacillales 225057|Acidithiobacillales J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM k141_11283_2 941449.dsx2_1651 8.61e-05 43.9 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2M8CA@213115|Desulfovibrionales 28221|Deltaproteobacteria O Protein of unknown function, DUF255 yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH k141_21061_2 1042375.AFPL01000015_gene2170 7.61e-90 274.0 COG1414@1|root,COG1414@2|Bacteria,1Q7BI@1224|Proteobacteria,1S1ZZ@1236|Gammaproteobacteria,469JE@72275|Alteromonadaceae 1236|Gammaproteobacteria K helix_turn_helix isocitrate lyase regulation - - - - - - - - - - - - HTH_IclR,IclR k141_21061_3 717774.Marme_1567 8.15e-25 99.4 COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,1S431@1236|Gammaproteobacteria,1XN3I@135619|Oceanospirillales 135619|Oceanospirillales E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k141_4265_1 998088.B565_0866 8.83e-12 64.3 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1Y3H9@135624|Aeromonadales 135624|Aeromonadales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_16828_1 1196324.A374_14350 3.74e-11 68.2 COG1266@1|root,COG1266@2|Bacteria,1UFRU@1239|Firmicutes,4IRAX@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_14047_1 1237149.C900_02644 2.32e-35 126.0 2CC1H@1|root,33P9C@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 k141_14047_2 1121904.ARBP01000001_gene5807 6.08e-07 51.6 COG1413@1|root,COG1413@2|Bacteria,4NXQU@976|Bacteroidetes 976|Bacteroidetes C lyase activity - - - - - - - - - - - - - k141_10556_1 633131.TR2A62_0195 1.28e-141 402.0 COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG3316 Transposase and inactivated derivatives - - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 k141_16111_1 1278309.KB907099_gene2415 6.6e-58 182.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XJQQ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 k141_7931_2 1122137.AQXF01000005_gene1003 5.13e-52 173.0 COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,2TSH8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I myo-inositol-1-phosphate synthase - - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth k141_20485_1 1122137.AQXF01000003_gene2130 4.26e-11 64.3 COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,2VFKD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k141_12798_1 1158756.AQXQ01000005_gene178 2.2e-07 56.2 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1WWC0@135613|Chromatiales 135613|Chromatiales T PFAM HPP family - - - - - - - - - - - - HPP k141_12798_2 2340.JV46_10490 4.68e-39 133.0 COG2920@1|root,COG2920@2|Bacteria,1NDX4@1224|Proteobacteria,1SGA8@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_12798_4 870187.Thini_2245 3.96e-29 110.0 COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,1SCVF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - MAPEG k141_10717_1 1163409.UUA_10571 1.65e-27 109.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1X31S@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 k141_10717_2 1123401.JHYQ01000001_gene1896 2.7e-25 100.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46014@72273|Thiotrichales 72273|Thiotrichales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k141_9940_1 323261.Noc_0342 4.66e-157 455.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PFAM peptidase - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_14182_1 377629.TERTU_4351 1.03e-192 542.0 COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,2PQ6D@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Pyridine nucleotide-disulphide oxidoreductase sqr - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_13485_1 713586.KB900536_gene609 3.17e-40 145.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales 135613|Chromatiales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_2281_1 631362.Thi970DRAFT_04937 4.26e-71 228.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales 135613|Chromatiales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_16961_2 1049564.TevJSym_ax00100 2.82e-31 119.0 COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1J7VM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_7198_1 713586.KB900536_gene619 1.58e-15 75.1 COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k141_7198_2 314345.SPV1_03473 4.02e-149 428.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria 1224|Proteobacteria T radical SAM - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM k141_916_1 1278309.KB907099_gene3023 4.44e-160 460.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XHG3@135619|Oceanospirillales 135619|Oceanospirillales F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_916_2 1278309.KB907099_gene3024 3.07e-267 754.0 COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XHGK@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) tmcA - 2.3.1.193 ko:K06957 - - - - ko00000,ko01000,ko03016 - - - DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3 k141_916_3 1278309.KB907099_gene3025 1.03e-117 345.0 COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1XJM0@135619|Oceanospirillales 135619|Oceanospirillales C Molybdenum cofactor sulfurase - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N k141_11406_1 760154.Sulba_2229 4.45e-69 230.0 COG4773@1|root,COG4773@2|Bacteria 2|Bacteria P Receptor - - - - - - - - - - - - OprD k141_11406_2 85643.Tmz1t_1305 9.64e-211 593.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,2KXYS@206389|Rhodocyclales 206389|Rhodocyclales G TRAP-type C4-dicarboxylate transport system, large permease - - - - - - - - - - - - DctM k141_11406_3 305700.B447_04287 1.4e-52 171.0 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2VYXV@28216|Betaproteobacteria 28216|Betaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_11406_4 85643.Tmz1t_1303 3.06e-103 310.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VP2F@28216|Betaproteobacteria 28216|Betaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_4442_1 365044.Pnap_1043 7.34e-86 268.0 2CEX8@1|root,32AEQ@2|Bacteria,1RII6@1224|Proteobacteria,2W2TE@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_21197_1 1288826.MSNKSG1_08063 2.45e-156 440.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,464V9@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind k141_21197_2 1288826.MSNKSG1_08058 8.3e-147 414.0 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,46413@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_21197_3 1288826.MSNKSG1_08053 1.45e-133 379.0 COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,464ST@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr k141_21197_4 1288826.MSNKSG1_08048 1.41e-307 837.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,4648D@72275|Alteromonadaceae 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_21197_5 1288826.MSNKSG1_08043 1.08e-241 664.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,46547@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_21197_6 1288826.MSNKSG1_08038 1.35e-49 157.0 COG2991@1|root,COG2991@2|Bacteria,1N8TF@1224|Proteobacteria,1SCB5@1236|Gammaproteobacteria,468G5@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K05952 - - - - ko00000 - - - NqrM k141_21197_7 1288826.MSNKSG1_08033 0.0 930.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,465C1@72275|Alteromonadaceae 1236|Gammaproteobacteria C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019725,GO:0022857,GO:0022890,GO:0034220,GO:0036094,GO:0042592,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363,GO:1902600 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_4669,iECs_1301.ECs4891,iZ_1308.Z5521 Pyr_redox_2,Pyr_redox_dim k141_21197_8 1288826.MSNKSG1_08028 1.57e-194 539.0 COG0584@1|root,COG0584@2|Bacteria,1RJ24@1224|Proteobacteria,1S6EE@1236|Gammaproteobacteria,46CZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria C glycerophosphoryl diester phosphodiesterase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_21197_9 1288826.MSNKSG1_08023 6.34e-276 754.0 COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,1S11K@1236|Gammaproteobacteria 1236|Gammaproteobacteria E 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase aroF - 2.5.1.54,5.4.99.5 ko:K03856,ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_21197_10 1288826.MSNKSG1_08018 1.31e-96 281.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,468DI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB k141_21197_11 1288826.MSNKSG1_08013 7.91e-220 607.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,465PU@72275|Alteromonadaceae 1236|Gammaproteobacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k141_21197_12 1288826.MSNKSG1_08008 5.17e-248 681.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,464FI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA GO:0002943,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus k141_21197_13 1288826.MSNKSG1_08003 5.2e-135 387.0 COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,1S295@1236|Gammaproteobacteria,466K7@72275|Alteromonadaceae 1236|Gammaproteobacteria GK ROK family - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK k141_11407_1 323261.Noc_2676 1.22e-60 198.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales 135613|Chromatiales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_9941_1 1288826.MSNKSG1_01903 3.98e-60 199.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RNHN@1236|Gammaproteobacteria,469NB@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acs-2 - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_9941_2 1288826.MSNKSG1_01908 1.34e-97 283.0 COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,1S44H@1236|Gammaproteobacteria,467PW@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT k141_12799_1 713587.THITH_02845 4.79e-34 129.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - PLDc_2 k141_12799_2 765914.ThisiDRAFT_0321 2.74e-66 212.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WXHR@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k141_19733_1 1278309.KB907099_gene2719 2.86e-115 356.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XIGX@135619|Oceanospirillales 135619|Oceanospirillales C formate dehydrogenase fdsA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_1637_1 1249627.D779_0933 4.35e-142 417.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales 135613|Chromatiales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_3036_1 999611.KI421504_gene2525 7.03e-94 285.0 COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,28255@191028|Leisingera 28211|Alphaproteobacteria E Glycine cleavage T-protein C-terminal barrel domain - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C,SnoaL_2 k141_3036_2 1278309.KB907101_gene435 7.91e-73 228.0 COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XIP0@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) - - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - Formyl_trans_N k141_19091_2 765912.Thimo_0056 4.12e-37 135.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1WWJP@135613|Chromatiales 135613|Chromatiales S Sterol-binding domain protein - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_19091_3 1051646.VITU9109_17803 1.08e-35 129.0 COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,1XXYG@135623|Vibrionales 135623|Vibrionales S membrane protein domain - - - - - - - - - - - - RDD k141_7199_1 1288826.MSNKSG1_09653 2.06e-192 544.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,465QH@72275|Alteromonadaceae 1236|Gammaproteobacteria CP COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit phaD - 1.6.5.3 ko:K00342,ko:K05561,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M k141_7199_2 1288826.MSNKSG1_09648 2.34e-74 223.0 COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,1SA5H@1236|Gammaproteobacteria,4682I@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1006 Multisubunit Na H antiporter, MnhC subunit phaC - - ko:K05560,ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 k141_4443_1 95619.PM1_0205510 5.05e-24 102.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase morA - - - - - - - - - - - EAL,GGDEF,PAS,PAS_8,PAS_9,dCache_2 k141_4443_2 748658.KB907319_gene764 1.43e-101 303.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_2282_1 1121374.KB891576_gene716 3.29e-98 317.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_2282_2 2340.JV46_15540 1.76e-15 74.3 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 k141_12800_1 887327.HMPREF0476_0473 4.93e-10 66.2 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,2KQ8N@206351|Neisseriales 206351|Neisseriales T Domain of unknown function (DUF3329) phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS_8 k141_17672_1 13333.ERN07644 2.14e-96 288.0 28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta 35493|Streptophyta U Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope ycf1 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0015031,GO:0015833,GO:0016020,GO:0019866,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0033036,GO:0042170,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - - - - - - - - - - Ycf1 k141_7933_2 1046714.AMRX01000001_gene1246 3.2e-52 195.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_213_1 1278309.KB907099_gene2480 0.0 1011.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_213_3 1278309.KB907099_gene2482 4.63e-79 235.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1XK8F@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional - - - - - - - - - - - - MerR_1 k141_16962_1 1168067.JAGP01000001_gene592 6.91e-27 105.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1S357@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B k141_16962_2 1121937.AUHJ01000002_gene3434 6.46e-92 281.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,46AVD@72275|Alteromonadaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_16962_3 1168067.JAGP01000001_gene591 1.33e-60 194.0 COG1082@1|root,COG1082@2|Bacteria,1Q3WR@1224|Proteobacteria,1S04R@1236|Gammaproteobacteria,461MT@72273|Thiotrichales 72273|Thiotrichales G Xylose isomerase - - - - - - - - - - - - - k141_3735_1 551275.KB899544_gene1508 3.13e-11 67.8 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,43WMM@69657|Hyphomonadaceae 28211|Alphaproteobacteria T COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg k141_11409_1 765912.Thimo_0147 5.52e-40 135.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,1WYI4@135613|Chromatiales 135613|Chromatiales P sulfur relay protein TusB DsrH - - - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_2283_1 1049564.TevJSym_aa01840 3.05e-66 216.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4G2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains zraR GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_7200_1 2340.JV46_12850 3.12e-98 295.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,1RZ6B@1236|Gammaproteobacteria,1J9XD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H PBP superfamily domain tupA - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 k141_1638_1 998674.ATTE01000001_gene532 1.45e-23 96.3 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,45ZWH@72273|Thiotrichales 72273|Thiotrichales I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_1638_2 765911.Thivi_3484 6.21e-114 340.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1WWIC@135613|Chromatiales 135613|Chromatiales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_4444_1 1026882.MAMP_01484 1.74e-77 243.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,45ZX2@72273|Thiotrichales 72273|Thiotrichales P PFAM sodium calcium exchanger - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_4444_2 1265502.KB905939_gene2387 8.51e-06 48.1 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,4ADJ3@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM VacJ family lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_19734_1 1461693.ATO10_11020 8.21e-76 248.0 COG3637@1|root,COG3637@2|Bacteria,1QV2K@1224|Proteobacteria,2TR2T@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Exopolysaccharide biosynthesis protein YbjH - - - - - - - - - - - - YjbH k141_8605_1 1408422.JHYF01000015_gene464 7.06e-67 210.0 COG1586@1|root,COG1586@2|Bacteria,1TQ7S@1239|Firmicutes,2480M@186801|Clostridia,36ET4@31979|Clostridiaceae 186801|Clostridia E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k141_8605_2 572477.Alvin_0173 4.97e-93 278.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1WWM4@135613|Chromatiales 135613|Chromatiales H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 k141_8605_4 1179226.AJXO01000009_gene2618 8.26e-29 123.0 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,4GXZ2@90964|Staphylococcaceae 91061|Bacilli C 4Fe-4S dicluster domain - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_17,Fer4_4,Fer4_8 k141_12118_1 314345.SPV1_09583 8.16e-119 364.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_3048_2 1123368.AUIS01000001_gene2029 1.39e-41 144.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,2NBWT@225057|Acidithiobacillales 225057|Acidithiobacillales IQ short-chain dehydrogenase reductase - - - - - - - - - - - - adh_short k141_17686_1 1278309.KB907100_gene2233 1.6e-172 495.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XI7E@135619|Oceanospirillales 135619|Oceanospirillales P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB - - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - - NhaB k141_17686_2 1278309.KB907100_gene2234 1.54e-162 456.0 COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1XI2I@135619|Oceanospirillales 135619|Oceanospirillales O Peroxiredoxin - - - - - - - - - - - - Glutaredoxin,Redoxin k141_17686_3 94624.Bpet3465 6.91e-66 214.0 COG3487@1|root,COG3487@2|Bacteria,1MX5H@1224|Proteobacteria,2VI9H@28216|Betaproteobacteria,3T442@506|Alcaligenaceae 28216|Betaproteobacteria P Imelysin - - - ko:K07231 - - - - ko00000 - - - Peptidase_M75 k141_6479_1 1384054.N790_08340 2.92e-42 147.0 COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,1RZ6C@1236|Gammaproteobacteria,1X6QA@135614|Xanthomonadales 135614|Xanthomonadales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k141_6479_2 323848.Nmul_A1979 3.63e-161 461.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,372H1@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_20506_1 1265313.HRUBRA_02262 4.93e-104 323.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4RW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DNA helicase uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_933_1 290398.Csal_2742 4.38e-143 410.0 COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,1XIFA@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K19337 - - - - ko00000,ko03000 - - - HTH_6,SIS k141_933_2 626887.J057_19725 3.32e-230 648.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,464A8@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf GO:0003674,GO:0003824,GO:0004345,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0009117,GO:0009372,GO:0009987,GO:0010699,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0023052,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - e_coli_core.b1852,iAF1260.b1852,iBWG_1329.BWG_1666,iE2348C_1286.E2348C_1977,iEC042_1314.EC042_2019,iECABU_c1320.ECABU_c21130,iECDH10B_1368.ECDH10B_1993,iECDH1ME8569_1439.ECDH1ME8569_1798,iECED1_1282.ECED1_2057,iECIAI39_1322.ECIAI39_1198,iECNA114_1301.ECNA114_1899,iECO26_1355.ECO26_2690,iECP_1309.ECP_1796,iECSF_1327.ECSF_1710,iECUMN_1333.ECUMN_2149,iECW_1372.ECW_m2026,iEKO11_1354.EKO11_1918,iEcDH1_1363.EcDH1_1789,iEcE24377_1341.EcE24377A_2082,iEcHS_1320.EcHS_A1944,iEcSMS35_1347.EcSMS35_1335,iEcolC_1368.EcolC_1780,iG2583_1286.G2583_2304,iJO1366.b1852,iJR904.b1852,iLF82_1304.LF82_3733,iNRG857_1313.NRG857_09280,iSDY_1059.SDY_1138,iWFL_1372.ECW_m2026,iY75_1357.Y75_RS09725,iYL1228.KPN_02367,ic_1306.c2265 G6PD_C,G6PD_N k141_933_3 1120963.KB894503_gene1967 1.87e-57 189.0 COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1S11C@1236|Gammaproteobacteria,2PZGD@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria G COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso k141_933_4 768066.HELO_3635 6.88e-48 161.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1XJQ5@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase k141_19098_1 392500.Swoo_3115 1.74e-87 265.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,2QATH@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_0281 THF_DHG_CYH,THF_DHG_CYH_C k141_19749_1 1278309.KB907104_gene821 1.61e-97 310.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XHS7@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the ClpA ClpB family - - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small k141_19235_1 571166.KI421509_gene4001 5.6e-76 243.0 COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Dehydrogenase nuoEF - 1.17.1.9 ko:K00122 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB k141_16357_1 1288826.MSNKSG1_16891 7.02e-109 320.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,464HS@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component - - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY k141_16357_2 768066.HELO_2583 1.69e-34 125.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XHIT@135619|Oceanospirillales 135619|Oceanospirillales EP (ABC) transporter, permease - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_13605_1 395493.BegalDRAFT_0465 3.25e-62 204.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,460IE@72273|Thiotrichales 72273|Thiotrichales U AAA domain - - - - - - - - - - - - AAA_22 k141_17075_1 697282.Mettu_0834 2.54e-71 225.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XE6R@135618|Methylococcales 135618|Methylococcales I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_17075_2 1260251.SPISAL_06505 3.68e-49 166.0 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1WZ46@135613|Chromatiales 135613|Chromatiales S PFAM electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_17075_3 396588.Tgr7_3151 2.31e-77 233.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales 135613|Chromatiales K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_17075_4 690850.Desaf_2364 6.06e-44 161.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_12242_2 1123368.AUIS01000005_gene371 5.71e-49 161.0 COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,1SA1H@1236|Gammaproteobacteria,2NCCT@225057|Acidithiobacillales 225057|Acidithiobacillales T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_1065_1 1278309.KB907100_gene2350 2.04e-152 447.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales 135619|Oceanospirillales L Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_7336_2 686340.Metal_2699 4.39e-69 226.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1XENA@135618|Methylococcales 135618|Methylococcales KLT kinase domain - - - - - - - - - - - - PP2C_2,Pkinase k141_21318_2 1349767.GJA_4701 2.65e-39 145.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,472DD@75682|Oxalobacteraceae 28216|Betaproteobacteria S protease with the C-terminal PDZ - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_21989_1 1242864.D187_007250 8.4e-23 107.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,439X6@68525|delta/epsilon subdivisions,2X1U7@28221|Deltaproteobacteria,2YWA9@29|Myxococcales 28221|Deltaproteobacteria T GHKL domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA k141_21989_2 1168065.DOK_06437 1.04e-63 207.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type phosphate phosphonate transport system periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_10096_1 1278309.KB907099_gene2459 5.95e-158 457.0 COG2204@1|root,COG2204@2|Bacteria,1QVPI@1224|Proteobacteria,1T2FZ@1236|Gammaproteobacteria,1XRSN@135619|Oceanospirillales 135619|Oceanospirillales T Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 k141_10096_2 1278309.KB907099_gene2458 3.41e-284 778.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1XHA8@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth k141_10096_3 1278309.KB907099_gene2457 4.91e-167 471.0 COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,1XIGJ@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the ompA family - - - ko:K21218 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_10096_4 1278309.KB907099_gene2456 9.48e-141 398.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1XH30@135619|Oceanospirillales 135619|Oceanospirillales L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt - - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T k141_10096_5 1120963.KB894493_gene2973 1.56e-22 91.3 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,2Q0KJ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O COG0450 Peroxiredoxin tsaA - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_3838_1 1278309.KB907099_gene3079 2.78e-137 391.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,1XIQY@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.149 ko:K08299 - - R10675 RC01095 ko00000,ko01000 - - - ECH_1 k141_3838_2 1278309.KB907099_gene3078 5.31e-264 724.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XI78@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_3838_3 1278309.KB907099_gene3077 0.0 928.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1XIE7@135619|Oceanospirillales 135619|Oceanospirillales C methylmalonate-semialdehyde dehydrogenase mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3838_4 1278309.KB907099_gene3074 1.78e-168 473.0 COG2207@1|root,COG2207@2|Bacteria,1QTSB@1224|Proteobacteria,1T356@1236|Gammaproteobacteria,1XRSU@135619|Oceanospirillales 135619|Oceanospirillales K AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_AraC k141_3838_5 1232683.ADIMK_3824 3.37e-58 184.0 COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria,46BN5@72275|Alteromonadaceae 1236|Gammaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase k141_3838_6 1278309.KB907099_gene3072 1.36e-77 233.0 COG1522@1|root,COG1522@2|Bacteria,1N2D6@1224|Proteobacteria,1S8VT@1236|Gammaproteobacteria,1XKP0@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_1800_1 91464.S7335_5034 4.47e-29 109.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1GYT4@1129|Synechococcus 1117|Cyanobacteria C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_4583_1 349124.Hhal_0475 1.78e-55 184.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1WWSX@135613|Chromatiales 135613|Chromatiales NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) - - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k141_4583_2 95619.PM1_0209870 1.09e-41 139.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_16374_1 1173024.KI912153_gene116 6.37e-05 52.0 COG0671@1|root,COG0671@2|Bacteria,1G6WU@1117|Cyanobacteria,1JJIT@1189|Stigonemataceae 1117|Cyanobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2 k141_1089_1 1123504.JQKD01000041_gene2857 2.59e-154 468.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2WGHK@28216|Betaproteobacteria,4AF4Y@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Cytochrome P450 - - 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_19247_1 1026882.MAMP_02700 7.21e-121 365.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4602V@72273|Thiotrichales 72273|Thiotrichales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_17089_1 1283300.ATXB01000001_gene1193 1.44e-47 161.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - DUF1295 k141_17089_2 887062.HGR_05424 9.82e-30 113.0 2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,2VVUJ@28216|Betaproteobacteria,4AID7@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_3204_1 314264.ROS217_11261 1.01e-92 273.0 COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,46P1F@74030|Roseovarius 28211|Alphaproteobacteria K Proline dehydrogenase transcriptional activator lrp GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - AsnC_trans_reg,HTH_24 k141_391_1 1288826.MSNKSG1_11453 1.95e-13 68.2 COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,1S58J@1236|Gammaproteobacteria,46AZ5@72275|Alteromonadaceae 1236|Gammaproteobacteria D Cobyrinic acid a,c-diamide synthase - - - - - - - - - - - - AAA_31 k141_391_2 225937.HP15_2766 1.15e-117 352.0 COG2199@1|root,COG3706@2|Bacteria,1RCH1@1224|Proteobacteria,1S3GU@1236|Gammaproteobacteria,466G7@72275|Alteromonadaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_391_3 1288826.MSNKSG1_11448 5.26e-206 571.0 COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,1T1IM@1236|Gammaproteobacteria,467KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 k141_391_4 930169.B5T_00392 2.19e-150 429.0 COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,1RXZC@1236|Gammaproteobacteria,1XPMD@135619|Oceanospirillales 135619|Oceanospirillales S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - - k141_391_5 1288826.MSNKSG1_11443 1.42e-121 347.0 COG4275@1|root,COG4275@2|Bacteria,1R8GI@1224|Proteobacteria,1SPK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ChrB domain-containing protein - - - - - - - - - - - - - k141_391_6 1288826.MSNKSG1_11438 8.78e-64 206.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,1RNP5@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_22003_1 1158762.KB898038_gene1892 1.44e-184 520.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales 135613|Chromatiales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_22003_3 472759.Nhal_3421 1.05e-147 427.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1WXVZ@135613|Chromatiales 135613|Chromatiales C Belongs to the AlaDH PNT family - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_22003_4 1117647.M5M_03100 1.46e-100 323.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1J4IX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_8728_1 754477.Q7C_1702 1.33e-101 309.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,460CN@72273|Thiotrichales 72273|Thiotrichales P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_8728_3 697282.Mettu_2473 1.02e-147 432.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XDTZ@135618|Methylococcales 135618|Methylococcales S modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k141_12958_1 1288826.MSNKSG1_04901 2.28e-38 141.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,46570@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_12958_2 1288826.MSNKSG1_04906 8e-173 483.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,464SB@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar basal body rod protein flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_12958_3 1288826.MSNKSG1_04911 4.3e-183 509.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,4647R@72275|Alteromonadaceae 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_12958_4 1288826.MSNKSG1_04916 3.4e-161 452.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,4675N@72275|Alteromonadaceae 1236|Gammaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH k141_12958_5 1288826.MSNKSG1_04921 1.73e-248 684.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,464ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_12958_6 1288826.MSNKSG1_04926 1.02e-231 639.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,466VA@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar rod assembly protein muramidase FlgJ flgJ GO:0003674,GO:0005198 - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k141_12958_7 1288826.MSNKSG1_04931 1.21e-69 228.0 COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,464V6@72275|Alteromonadaceae 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_10122_1 1278309.KB907101_gene521 4.4e-118 352.0 COG3064@1|root,COG3064@2|Bacteria,1RINZ@1224|Proteobacteria,1S7TN@1236|Gammaproteobacteria,1XM41@135619|Oceanospirillales 135619|Oceanospirillales M Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 k141_10122_2 1278309.KB907101_gene522 4.58e-147 420.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XHEF@135619|Oceanospirillales 135619|Oceanospirillales S ATPase, AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_15001_1 349102.Rsph17025_2804 3.36e-41 142.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,1FCKM@1060|Rhodobacter 28211|Alphaproteobacteria H Glutathione S-transferase, N-terminal domain yibF - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 k141_15001_2 1472418.BBJC01000001_gene828 3.88e-17 77.0 2ESC7@1|root,33JX0@2|Bacteria,1NHWS@1224|Proteobacteria,2UMQT@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_392_1 998674.ATTE01000001_gene213 2.88e-53 172.0 COG0393@1|root,COG0393@2|Bacteria,1N6BK@1224|Proteobacteria,1SAFJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 k141_5258_1 1288826.MSNKSG1_12092 7.11e-125 359.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,4659G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC k141_5258_2 1288826.MSNKSG1_12097 6.86e-95 281.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,464CI@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k141_9388_1 399739.Pmen_1835 9.67e-95 282.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1YDT7@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Belongs to the SUA5 family yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Sua5_yciO_yrdC k141_1090_1 396588.Tgr7_2686 9.67e-56 179.0 COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,1SA1H@1236|Gammaproteobacteria,1X12H@135613|Chromatiales 135613|Chromatiales T Cyclic nucleotide-binding domain - - - - - - - - - - - - cNMP_binding k141_8121_1 1232683.ADIMK_0702 3.24e-105 320.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RQ89@1236|Gammaproteobacteria,46A5X@72275|Alteromonadaceae 1236|Gammaproteobacteria C FAD dependent oxidoreductase puuB1 - - - - - - - - - - iJN746.PP_5257 DAO k141_8121_2 626887.J057_10566 1.05e-24 99.8 COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,464AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S DUF1338 - - - - - - - - - - - - DUF1338 k141_2461_1 1288826.MSNKSG1_11438 4.76e-209 583.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,1RNP5@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_16375_1 1208321.D104_14340 6.9e-53 171.0 COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,1S93W@1236|Gammaproteobacteria,1XKRX@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator, MarR - - - - - - - - - - - - MarR k141_16375_2 935840.JAEQ01000009_gene1351 2.32e-63 201.0 COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,43HRH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Amidohydrolase MA20_05990 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 k141_393_1 2340.JV46_24530 1.11e-50 166.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1J68X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB k141_7348_1 1288826.MSNKSG1_15442 1.91e-78 235.0 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,467F4@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - 1.6.5.3 ko:K00127,ko:K00334 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_7348_2 1288826.MSNKSG1_15437 2.41e-244 672.0 COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,1RS4Y@1236|Gammaproteobacteria,4668M@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2005 N-terminal domain of molybdenum-binding protein - - - - - - - - - - - - HTH_1,HTH_17,PBP_like k141_13631_1 1288826.MSNKSG1_16496 2.86e-111 325.0 28IWY@1|root,2Z8V1@2|Bacteria,1R9PZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_13631_2 1288826.MSNKSG1_16501 2.7e-243 672.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T1Q9@1236|Gammaproteobacteria,46CPR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_13631_3 1288826.MSNKSG1_16506 3.39e-175 489.0 COG2227@1|root,COG2227@2|Bacteria,1QXGB@1224|Proteobacteria,1T3BH@1236|Gammaproteobacteria,46D52@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k141_13631_4 1288826.MSNKSG1_16511 7.38e-224 617.0 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,1RRBB@1236|Gammaproteobacteria,46AD6@72275|Alteromonadaceae 1236|Gammaproteobacteria S Beta-lactamase superfamily domain meh - - - - - - - - - - - Lactamase_B k141_13631_5 1288826.MSNKSG1_16516 2.21e-10 60.8 COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,465KR@72275|Alteromonadaceae 1236|Gammaproteobacteria K transcriptional pdhR - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_9389_1 573413.Spirs_4181 8.54e-56 182.0 COG0656@1|root,COG0656@2|Bacteria,2J5XV@203691|Spirochaetes 203691|Spirochaetes S aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_9389_2 1038866.KB902773_gene868 6.28e-09 55.1 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,3JYIP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 k141_17823_1 1278309.KB907101_gene769 3.38e-66 202.0 COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,1S5AN@1236|Gammaproteobacteria,1XJUH@135619|Oceanospirillales 135619|Oceanospirillales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_17823_2 521674.Plim_1161 3.02e-58 187.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Acetyltransf_3 k141_17823_3 1042375.AFPL01000006_gene2944 5.79e-31 111.0 2CZ7C@1|root,32T5R@2|Bacteria,1N0CN@1224|Proteobacteria,1S9C8@1236|Gammaproteobacteria,468D8@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1091_2 757424.Hsero_3714 1.5e-23 101.0 COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2VJR3@28216|Betaproteobacteria,473MG@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabF3 - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_19249_1 1242864.D187_003015 5.12e-22 100.0 COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,PAS_4 k141_8122_1 472759.Nhal_0874 3.68e-32 126.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2066) - - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_16376_1 472759.Nhal_2777 5.96e-14 77.4 COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,1WXWT@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_15936_1 768671.ThimaDRAFT_0979 2.69e-44 153.0 COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_9559_1 1279017.AQYJ01000026_gene58 8.22e-96 321.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B k141_3380_1 340.xcc-b100_2144 6.13e-19 91.3 COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X3RD@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase rpfC - 2.7.13.3 ko:K10715 ko02020,ko02024,map02020,map02024 M00517 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,Hpt,Response_reg k141_22187_1 1115515.EV102420_02_03300 3.93e-37 132.0 COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,1RPAQ@1236|Gammaproteobacteria,3XP8D@561|Escherichia 1236|Gammaproteobacteria C Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC kefF GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016655,GO:0022898,GO:0022900,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032553,GO:0032879,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0036094,GO:0043167,GO:0043168,GO:0043269,GO:0043270,GO:0044093,GO:0044237,GO:0048037,GO:0048518,GO:0050662,GO:0050789,GO:0051049,GO:0051050,GO:0055114,GO:0065007,GO:0065009,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K11746 - - - - ko00000,ko02000 2.A.37.1.1 - - Flavodoxin_2 k141_5479_1 1188256.BASI01000001_gene656 3.07e-114 337.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,3FCKK@34008|Rhodovulum 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 k141_5479_2 1123360.thalar_02983 1.76e-05 46.2 COG0784@1|root,COG0784@2|Bacteria 2|Bacteria T Response regulator, receiver - - - - - - - - - - - - HATPase_c,HDOD,HisKA,PAS_3,PAS_9,Response_reg k141_18704_2 1094184.KWO_0117790 2.66e-14 75.9 COG0392@1|root,COG0392@2|Bacteria,1R4IS@1224|Proteobacteria,1RYQY@1236|Gammaproteobacteria,1XAI1@135614|Xanthomonadales 135614|Xanthomonadales S integral membrane protein - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM k141_4785_1 666685.R2APBS1_0141 2.18e-87 276.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1X3S1@135614|Xanthomonadales 135614|Xanthomonadales H receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k141_3381_1 1121374.KB891585_gene1940 3.87e-66 215.0 COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E M18 family aminopeptidase apeB GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 k141_6115_1 1384056.N787_09870 3.57e-18 85.5 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1X381@135614|Xanthomonadales 135614|Xanthomonadales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_6115_2 1232683.ADIMK_0794 1.45e-48 172.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,464F2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_1301_1 323848.Nmul_A2390 2.45e-47 161.0 COG3916@1|root,COG3916@2|Bacteria,1RB3V@1224|Proteobacteria,2VTA5@28216|Betaproteobacteria,372Y1@32003|Nitrosomonadales 28216|Betaproteobacteria H Autoinducer synthase - - 2.3.1.184 ko:K13060,ko:K13061 ko00270,ko01100,ko02020,ko02024,ko02025,map00270,map01100,map02020,map02024,map02025 - R08939,R08940 RC00021,RC00039 ko00000,ko00001,ko01000 - - - Autoind_synth k141_19402_1 1278309.KB907099_gene2405 1.93e-69 216.0 COG2186@1|root,COG2186@2|Bacteria,1NXAS@1224|Proteobacteria,1SYY0@1236|Gammaproteobacteria,1XRJC@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_19402_2 1278309.KB907099_gene2406 5.85e-209 580.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1XHDE@135619|Oceanospirillales 135619|Oceanospirillales C alcohol dehydrogenase - - - ko:K19745 ko00640,ko01100,map00640,map01100 - R00919 RC00095 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_19402_4 1278309.KB907099_gene2408 6.76e-79 246.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1XJMJ@135619|Oceanospirillales 135619|Oceanospirillales P protein involved in response to NO nnrS - - ko:K07234 - - - - ko00000 - - - NnrS k141_10330_1 1288826.MSNKSG1_08208 2.08e-116 336.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,464ZM@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Cytochrom_C_asm k141_10330_2 1288826.MSNKSG1_08213 1.35e-150 426.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,466DX@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECO111_1330.ECO111_2936,iYL1228.KPN_02080 CcmB k141_10330_3 1288826.MSNKSG1_08218 2.15e-149 420.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,466VK@72275|Alteromonadaceae 1236|Gammaproteobacteria O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479 ABC_tran k141_10330_4 1288826.MSNKSG1_08223 2.83e-62 202.0 2EIBS@1|root,33C35@2|Bacteria,1QVXE@1224|Proteobacteria,1SHEY@1236|Gammaproteobacteria,468VS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flagellar hook-length control protein FliK - - - - - - - - - - - - Flg_hook k141_6116_1 768670.Calni_1741 7.72e-49 163.0 COG0279@1|root,COG0279@2|Bacteria,2GFD6@200930|Deferribacteres 200930|Deferribacteres G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k141_572_1 1278309.KB907101_gene438 2.36e-68 208.0 2DNU1@1|root,32Z4S@2|Bacteria,1N8FB@1224|Proteobacteria,1T0XA@1236|Gammaproteobacteria,1XKJE@135619|Oceanospirillales 135619|Oceanospirillales S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like k141_572_2 1278309.KB907101_gene439 6.94e-71 217.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria,1XKHX@135619|Oceanospirillales 135619|Oceanospirillales M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - 3.4.17.13 ko:K13694,ko:K13695 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k141_572_3 1278309.KB907101_gene440 9.35e-99 288.0 2AQ2U@1|root,31F7Z@2|Bacteria,1R8TD@1224|Proteobacteria,1S0VX@1236|Gammaproteobacteria,1XKC4@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2947) - - - - - - - - - - - - DUF2947 k141_572_4 1278309.KB907101_gene441 2.22e-133 383.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria,1XJET@135619|Oceanospirillales 135619|Oceanospirillales L endonuclease I - - 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Endonuclease_1 k141_572_5 1278309.KB907101_gene442 4.78e-152 432.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XKSN@135619|Oceanospirillales 135619|Oceanospirillales T Response regulator receiver - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k141_572_6 1278309.KB907101_gene443 0.0 1495.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9,dCache_1 k141_572_7 1278309.KB907101_gene444 1.25e-120 361.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XH9G@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter - - - ko:K18893 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_5480_1 396588.Tgr7_2237 3.88e-96 288.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1WX1Y@135613|Chromatiales 135613|Chromatiales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg k141_4786_1 1134474.O59_004010 8.21e-85 270.0 2B1Z8@1|root,31UFT@2|Bacteria,1RHY7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - TIR_2 k141_11705_2 1236514.BAKL01000098_gene5151 5.34e-20 90.1 COG1083@1|root,COG1083@2|Bacteria,4NM98@976|Bacteroidetes,2FR2G@200643|Bacteroidia,4AQDY@815|Bacteroidaceae 976|Bacteroidetes M Psort location Cytoplasmic, score - - 2.7.7.43 ko:K00983 ko00520,ko01100,map00520,map01100 - R01117,R04215 RC00152 ko00000,ko00001,ko01000 - - - CTP_transf_3 k141_15937_1 1278309.KB907099_gene2961 2.62e-75 230.0 COG1802@1|root,COG1802@2|Bacteria,1MVXM@1224|Proteobacteria,1S0ME@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - FCD,GntR k141_15937_2 1278309.KB907099_gene2962 3.92e-149 430.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHZD@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamine synthetase family - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_6771_1 1026882.MAMP_00733 4.62e-113 336.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,461T8@72273|Thiotrichales 72273|Thiotrichales V ABC-type multidrug transport system ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_18056_1 929703.KE386491_gene1579 1.25e-44 163.0 COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia 976|Bacteroidetes I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_10331_1 1288826.MSNKSG1_07348 8.23e-109 320.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,465QS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph k141_20744_1 1120951.AUBG01000006_gene524 2.34e-07 54.3 COG4123@1|root,COG4123@2|Bacteria,4NGDY@976|Bacteroidetes,1HZFW@117743|Flavobacteriia 976|Bacteroidetes S Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_20744_2 82996.sch_16285 7.87e-72 231.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,403DR@613|Serratia 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_3401_1 987059.RBXJA2T_03688 1.72e-21 92.4 COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,1KK6F@119065|unclassified Burkholderiales 28216|Betaproteobacteria H 2-dehydropantoate 2-reductase panE2 - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_3401_2 1122201.AUAZ01000023_gene3018 8.16e-136 396.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RP9D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Trap-type c4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_7553_1 1123401.JHYQ01000003_gene2034 4.18e-99 294.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,46080@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N k141_14454_1 1123354.AUDR01000015_gene208 1.88e-53 179.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,1KRJB@119069|Hydrogenophilales 119069|Hydrogenophilales NT Two component signalling adaptor domain - - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_12504_1 1144310.PMI07_006411 7.52e-102 311.0 COG1012@1|root,COG1012@2|Bacteria,1NR51@1224|Proteobacteria,2UPF2@28211|Alphaproteobacteria,4BJ7A@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh k141_18723_1 317025.Tcr_0431 3.7e-21 88.6 2EPRN@1|root,33HC6@2|Bacteria,1NI9T@1224|Proteobacteria,1SICJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18723_2 1168067.JAGP01000001_gene1852 2.52e-52 181.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales 72273|Thiotrichales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_9579_1 1278309.KB907104_gene881 1.03e-106 316.0 COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,1XI9T@135619|Oceanospirillales 135619|Oceanospirillales P Voltage-dependent anion channel - - - - - - - - - - - - SLAC1 k141_9579_2 1121937.AUHJ01000004_gene991 2.59e-06 50.1 COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,468BD@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9579_3 261292.Nit79A3_3206 1.37e-131 381.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,372US@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF692) - - - ko:K09930 - - - - ko00000 - - - DUF692 k141_9579_4 207954.MED92_16405 1.83e-103 307.0 COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1XJMH@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09929 - - - - ko00000 - - - DUF2063 k141_10355_2 1158165.KB898877_gene1220 1.61e-43 144.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_22202_1 1123392.AQWL01000006_gene638 8.72e-35 137.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KRZ9@119069|Hydrogenophilales 119069|Hydrogenophilales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_18076_1 983545.Glaag_4490 1.31e-78 258.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG2217 Cation transport ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_14455_1 1288826.MSNKSG1_16886 6.27e-108 317.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,46677@72275|Alteromonadaceae 1236|Gammaproteobacteria EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k141_21527_1 1123288.SOV_2c01710 2.11e-06 54.7 COG2199@1|root,COG2199@2|Bacteria,1V04Z@1239|Firmicutes,4H8VQ@909932|Negativicutes 909932|Negativicutes T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_3402_1 64471.sync_2676 1.09e-36 129.0 COG0346@1|root,COG0346@2|Bacteria,1G7VE@1117|Cyanobacteria,1H174@1129|Synechococcus 1117|Cyanobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - k141_3402_2 153948.NAL212_0766 6.23e-34 126.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,3725F@32003|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k141_1316_1 1288826.MSNKSG1_01298 0.0 1165.0 COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k141_1316_2 1288826.MSNKSG1_01303 0.0 1167.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,465YM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_1316_3 1288826.MSNKSG1_01308 2.83e-197 546.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,464B8@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k141_1316_4 1288826.MSNKSG1_01313 1.39e-82 244.0 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,468QS@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 k141_1316_5 1288826.MSNKSG1_01318 3.4e-159 446.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,466PY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm k141_1316_6 1288826.MSNKSG1_01323 9.57e-213 588.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,464IK@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_1316_7 1288826.MSNKSG1_01328 4.64e-168 470.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,46776@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_1316_8 1288826.MSNKSG1_01333 3.81e-168 470.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,464QE@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 PdxJ k141_1316_9 1288826.MSNKSG1_01338 3.44e-203 588.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg k141_16603_1 1288826.MSNKSG1_10343 1.39e-251 696.0 COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,1RPW8@1236|Gammaproteobacteria,465IF@72275|Alteromonadaceae 1236|Gammaproteobacteria Q cytochrome P450 - - - - - - - - - - - - p450 k141_16603_2 1288826.MSNKSG1_10313 5.4e-27 103.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria,466CS@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the GST superfamily gstA - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_3 k141_11076_1 574966.KB898650_gene451 3.06e-40 152.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1XH2A@135619|Oceanospirillales 135619|Oceanospirillales M PFAM glycosyl transferase family 39 - - - - - - - - - - - - PMT,PMT_2 k141_12505_1 1082933.MEA186_18108 8.76e-48 166.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,43M00@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k141_13181_2 1096546.WYO_3587 2.03e-05 48.5 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VFW2@28211|Alphaproteobacteria,1JU3K@119045|Methylobacteriaceae 28211|Alphaproteobacteria I TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N k141_13860_1 1288826.MSNKSG1_09063 0.0 939.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,464PN@72275|Alteromonadaceae 1236|Gammaproteobacteria J COG1530 Ribonucleases G and E rng GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 k141_13860_2 1288826.MSNKSG1_09068 1.65e-125 358.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,467B9@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation yhdE GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - ko:K06287 - - - - ko00000 - - - Maf k141_7555_1 1461579.CCNK01000007_gene194 2.04e-39 135.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1Y8UG@135625|Pasteurellales 135625|Pasteurellales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k141_1974_1 1348114.OM33_21275 3.96e-09 58.2 COG3292@1|root,COG3829@1|root,COG4191@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RRSF@1236|Gammaproteobacteria,2Q1NM@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T Two component regulator propeller - - - - - - - - - - - - HATPase_c,PAS_3,Reg_prop,Y_Y_Y k141_1974_2 1523503.JPMY01000029_gene1148 2.56e-57 184.0 2DMP1@1|root,32SS8@2|Bacteria,1N6W6@1224|Proteobacteria,1T0UP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3237) - - - - - - - - - - - - DUF3237 k141_4002_1 1100720.ALKN01000028_gene2533 2.65e-23 99.8 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria,4A9NP@80864|Comamonadaceae 28216|Betaproteobacteria S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_4002_2 317025.Tcr_1541 5.27e-132 385.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales 72273|Thiotrichales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_5492_1 1137799.GZ78_02470 1.56e-76 255.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XHH3@135619|Oceanospirillales 135619|Oceanospirillales M penicillin-binding protein mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_21528_1 177437.HRM2_32920 2.95e-36 123.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales 28221|Deltaproteobacteria K PFAM Cold-shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_21528_2 879212.DespoDRAFT_00144 1.8e-07 50.4 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MJSM@213118|Desulfobacterales 28221|Deltaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_12506_1 1237149.C900_04800 2.22e-92 276.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_10357_1 1049564.TevJSym_ab01230 1.41e-62 202.0 COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H protein methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_7556_1 396588.Tgr7_2292 4.11e-48 167.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_7556_2 395493.BegalDRAFT_0363 7.21e-18 81.6 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,46094@72273|Thiotrichales 72273|Thiotrichales T PhoH-like protein - - - ko:K06217 - - - - ko00000 - - - PhoH k141_13182_1 1298593.TOL_1179 1.28e-79 258.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales 135619|Oceanospirillales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_3404_1 765911.Thivi_3209 1.16e-98 300.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales 135613|Chromatiales P PFAM Citrate transporter - - - - - - - - - - - - CitMHS k141_17300_1 626887.J057_08796 9.42e-32 130.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465M4@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_1975_1 1288826.MSNKSG1_06578 4.46e-125 360.0 COG2885@1|root,COG2885@2|Bacteria,1NF3D@1224|Proteobacteria,1SBSW@1236|Gammaproteobacteria,468ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of unknown function (DUF4892) - - - - - - - - - - - - DUF4892 k141_1975_2 1288826.MSNKSG1_06573 1.78e-14 72.4 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,4641H@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k141_2827_1 1408473.JHXO01000005_gene1580 7.25e-109 330.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,2FQJ2@200643|Bacteroidia 976|Bacteroidetes V beta-lactamase - - - - - - - - - - - - Beta-lactamase k141_11890_1 357804.Ping_2327 6.85e-59 201.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,2QJ72@267894|Psychromonadaceae 1236|Gammaproteobacteria P Chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_11890_2 983917.RGE_42590 7.01e-55 182.0 COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,2VP4J@28216|Betaproteobacteria 28216|Betaproteobacteria IM Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 k141_37_1 1123401.JHYQ01000002_gene2603 4.78e-34 120.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,461HI@72273|Thiotrichales 72273|Thiotrichales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF,QueF_N k141_747_2 86106.I862_00240 3.08e-18 85.1 COG0671@1|root,COG0671@2|Bacteria,1N4GM@1224|Proteobacteria,2TURF@28211|Alphaproteobacteria 28211|Alphaproteobacteria I PAP2 superfamily MA20_43480 - - ko:K12978 - - - - ko00000,ko01000,ko01005 - - - PAP2 k141_14701_1 1193181.BN10_1010011 3.44e-35 129.0 COG0847@1|root,COG0847@2|Bacteria,2IKNT@201174|Actinobacteria,4FH6A@85021|Intrasporangiaceae 201174|Actinobacteria L EXOIII dnaQ2 - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_14701_2 485915.Dret_2478 1.3e-08 57.8 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria,2M9E2@213115|Desulfovibrionales 28221|Deltaproteobacteria T CBS domain containing protein - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_16069_1 391593.RCCS2_17286 2e-57 198.0 COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,2P1YX@2433|Roseobacter 28211|Alphaproteobacteria S membrane metal-binding protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 k141_4916_1 1288826.MSNKSG1_08913 5.62e-95 288.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,464MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) IV02_13580 - - - - - - - - - - - DUF1329 k141_11219_1 767434.Fraau_2212 5.54e-19 87.8 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1X4P4@135614|Xanthomonadales 135614|Xanthomonadales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N k141_20978_1 318167.Sfri_2291 4.2e-180 528.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,2QAEU@267890|Shewanellaceae 1236|Gammaproteobacteria P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_18168_1 1278309.KB907104_gene916 1.19e-43 160.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales 135619|Oceanospirillales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_18868_1 1218352.B597_016405 3.05e-52 171.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1RQ26@1236|Gammaproteobacteria,1Z2MB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily attM - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B k141_18868_2 1301098.PKB_2171 1.75e-98 291.0 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RU8R@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_18868_3 1323663.AROI01000023_gene1497 1.14e-159 450.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1SITE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase k141_18868_4 644801.Psest_2359 5.55e-90 275.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,1YZQH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_3524_1 501479.ACNW01000080_gene4625 3.03e-10 59.7 COG3090@1|root,COG3090@2|Bacteria,1RH2H@1224|Proteobacteria,2UBPW@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - - - - - - - - - - DctQ k141_3524_2 501479.ACNW01000080_gene4626 8.76e-99 300.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_13983_2 1286106.MPL1_00692 4.86e-57 186.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,45ZW9@72273|Thiotrichales 72273|Thiotrichales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_7724_1 395493.BegalDRAFT_1677 1.46e-259 732.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales 72273|Thiotrichales O ATP-dependent Clp protease ATP-binding subunit ClpA - - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_7724_2 999141.GME_06559 1.35e-40 134.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1XKHQ@135619|Oceanospirillales 135619|Oceanospirillales J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a k141_20979_1 395494.Galf_0151 5.26e-30 114.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales 28216|Betaproteobacteria H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k141_20979_2 1122201.AUAZ01000040_gene3810 3.66e-29 111.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,46740@72275|Alteromonadaceae 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_10505_1 545264.KB898750_gene308 8.17e-188 548.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales 135613|Chromatiales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k141_1433_1 1415754.JQMK01000006_gene3770 3.09e-115 353.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal k141_1433_2 270374.MELB17_13322 4.17e-90 266.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,466WN@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs iorA - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_1433_3 1304885.AUEY01000009_gene1949 1.43e-111 334.0 COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,43CQR@68525|delta/epsilon subdivisions,2X7Y7@28221|Deltaproteobacteria,2MPPF@213118|Desulfobacterales 28221|Deltaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_N,HTH_18 k141_1433_4 398767.Glov_1440 5.19e-152 433.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,42PWU@68525|delta/epsilon subdivisions,2X5GP@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red k141_14702_2 377629.TERTU_2618 1.33e-08 55.8 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,2PN1M@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L Exonuclease VII, large subunit xseA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_4917_1 998674.ATTE01000001_gene3666 1.11e-16 78.6 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,45ZSA@72273|Thiotrichales 72273|Thiotrichales O PFAM Carbamoyltransferase - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k141_4917_2 998674.ATTE01000001_gene3667 1.12e-28 108.0 COG2192@1|root,COG2192@2|Bacteria,1R3MX@1224|Proteobacteria,1T69R@1236|Gammaproteobacteria 1236|Gammaproteobacteria O nodulation - - - - - - - - - - - - - k141_4917_3 998674.ATTE01000001_gene3668 2.01e-06 45.4 2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,1SHN2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_2126_1 349124.Hhal_0885 3.58e-18 80.1 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales 135613|Chromatiales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_2126_2 1245471.PCA10_03320 6.89e-88 284.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1YDBG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_13984_1 396588.Tgr7_2545 9.26e-32 112.0 2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_38_1 717772.THIAE_08950 1.58e-35 124.0 2F2WS@1|root,33VSD@2|Bacteria,1NWN4@1224|Proteobacteria,1SPNS@1236|Gammaproteobacteria,462GM@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_38_2 1168067.JAGP01000001_gene1466 7.26e-52 171.0 COG1344@1|root,COG1344@2|Bacteria,1MWE0@1224|Proteobacteria,1RYAM@1236|Gammaproteobacteria,462FI@72273|Thiotrichales 72273|Thiotrichales N Bacterial flagellin C-terminal helical region - - - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k141_18169_1 1051985.l11_12120 2.88e-75 238.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VN9Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Beta-lactamase superfamily domain - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 k141_11220_1 316067.Geob_3427 7.8e-34 126.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria 1224|Proteobacteria GM Nad-dependent epimerase dehydratase yeeZ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind k141_11220_2 396588.Tgr7_0025 6.37e-124 363.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_9803_2 2340.JV46_02820 1.5e-139 403.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1J4PA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935 Aminotran_5 k141_16773_1 396588.Tgr7_2238 2.01e-28 108.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1WZS4@135613|Chromatiales 135613|Chromatiales S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 k141_16773_3 1304275.C41B8_06017 1.58e-56 203.0 COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c k141_13299_1 1288826.MSNKSG1_15467 1.25e-53 174.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,464YT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria HA62_17960 - - - - - - - - - - - Metallophos,Metallophos_2 k141_13299_2 1288826.MSNKSG1_15462 4.34e-46 148.0 2E4CR@1|root,32Z86@2|Bacteria,1N9YH@1224|Proteobacteria,1SD46@1236|Gammaproteobacteria,468W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S NADH-dependant formate dehydrogenase delta subunit FdsD - - 1.17.1.9 ko:K00126 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - FdsD k141_13299_3 1288826.MSNKSG1_15457 1.39e-200 556.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,466A1@72275|Alteromonadaceae 1236|Gammaproteobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_13299_4 1288826.MSNKSG1_15452 4.05e-145 435.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,469S2@72275|Alteromonadaceae 1236|Gammaproteobacteria C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region fdhF GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 ko:K00123,ko:K22015 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - iECBD_1354.ECBD_3953 Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_7029_1 1397527.Q670_14655 1.96e-59 184.0 COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,1S941@1236|Gammaproteobacteria,1XMB6@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HxlR k141_7029_2 225937.HP15_1685 2.14e-123 353.0 COG2249@1|root,COG2249@2|Bacteria,1MWV9@1224|Proteobacteria,1RQ16@1236|Gammaproteobacteria,469K9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flavodoxin-like fold - - - ko:K03923 - - - - ko00000 - - - Flavodoxin_2 k141_7029_3 1397527.Q670_14670 6.99e-30 109.0 COG3791@1|root,COG3791@2|Bacteria 2|Bacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_20980_1 491952.Mar181_1481 1.42e-133 390.0 COG1653@1|root,COG1653@2|Bacteria,1R5DC@1224|Proteobacteria,1S3CM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G extracellular solute-binding - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 k141_20980_2 515620.EUBELI_20430 9.62e-08 54.3 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25YIF@186806|Eubacteriaceae 186801|Clostridia T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,SnoaL_3 k141_20265_2 207954.MED92_06308 1.47e-160 473.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XH8H@135619|Oceanospirillales 135619|Oceanospirillales T FOG PAS PAC domain - - - - - - - - - - - - MCPsignal,PAS_3 k141_20265_3 344747.PM8797T_02909 1.82e-51 205.0 COG0642@1|root,COG1352@1|root,COG2202@1|root,COG5000@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,2IWSR@203682|Planctomycetes 203682|Planctomycetes NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg k141_3526_1 1049564.TevJSym_ad00700 3.93e-15 70.9 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1J5Y6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSFV_1184.SFV_0380 DMRL_synthase k141_3526_2 349521.HCH_05953 7.31e-38 133.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XK4R@135619|Oceanospirillales 135619|Oceanospirillales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_6299_1 1278309.KB907099_gene3120 2.94e-131 381.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XI3K@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_6299_2 1278309.KB907099_gene3119 1.6e-98 291.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,1XJHR@135619|Oceanospirillales 135619|Oceanospirillales S CBS domain containing protein - - - - - - - - - - - - CBS k141_6299_3 501479.ACNW01000066_gene3245 1.34e-08 54.3 COG5457@1|root,COG5457@2|Bacteria,1Q1SW@1224|Proteobacteria,2UJEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1127) - - - - - - - - - - - - DUF1127 k141_6299_4 1278309.KB907099_gene3118 0.0 869.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1XHYA@135619|Oceanospirillales 135619|Oceanospirillales K containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR k141_16071_1 159450.NH14_11955 2.58e-39 149.0 COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2VIHY@28216|Betaproteobacteria,1K26P@119060|Burkholderiaceae 28216|Betaproteobacteria P Predicted Permease Membrane Region - - - ko:K07085 - - - - ko00000 2.A.81 - - Asp-Al_Ex,TrkA_C k141_18170_1 713586.KB900536_gene1141 9.25e-78 248.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_15416_1 95619.PM1_0223685 2.7e-164 491.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the GcvT family - - 1.5.3.1 ko:K00302 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 k141_15416_2 1380358.JADJ01000012_gene824 8.85e-50 159.0 COG4311@1|root,COG4311@2|Bacteria,1N2E9@1224|Proteobacteria,1S8ST@1236|Gammaproteobacteria 1236|Gammaproteobacteria E sarcosine oxidase - - 1.5.3.1 ko:K00304 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - SoxD k141_15416_3 717774.Marme_2428 1.03e-269 741.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,1XIN0@135619|Oceanospirillales 135619|Oceanospirillales E Sarcosine oxidase, subunit beta - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO k141_15416_4 999141.GME_14795 6.42e-71 222.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XHW1@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate - - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C k141_2842_1 1504672.669783715 4.1e-12 68.6 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,4AC80@80864|Comamonadaceae 28216|Betaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_2842_2 195105.CN97_12860 1.25e-08 55.5 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_6320_1 1286106.MPL1_03338 1.51e-78 242.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,460P3@72273|Thiotrichales 72273|Thiotrichales M lipoprotein - - - ko:K04754 - - - - ko00000 - - - MlaA k141_8419_2 757424.Hsero_1285 8.44e-68 216.0 COG0583@1|root,COG0583@2|Bacteria,1MW08@1224|Proteobacteria,2VKPC@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_10521_1 1121918.ARWE01000001_gene2909 1.09e-53 188.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,42SXG@68525|delta/epsilon subdivisions,2WP6Y@28221|Deltaproteobacteria,43THM@69541|Desulfuromonadales 28221|Deltaproteobacteria I SNARE associated Golgi protein - - - - - - - - - - - - LssY_C,PAP2,SNARE_assoc k141_18177_1 626887.J057_19030 2.18e-67 218.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,464FC@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_13316_1 395493.BegalDRAFT_3018 4.61e-53 184.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,45ZQG@72273|Thiotrichales 72273|Thiotrichales G 4-alpha-glucanotransferase - - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 k141_20290_1 1122201.AUAZ01000010_gene2577 2.07e-14 80.5 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4664A@72275|Alteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3 k141_21013_1 1288826.MSNKSG1_06218 3.21e-115 337.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,465C3@72275|Alteromonadaceae 1236|Gammaproteobacteria I desaturase desC - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_21013_2 1288826.MSNKSG1_06213 1.94e-114 337.0 COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,1S3X1@1236|Gammaproteobacteria,46BAC@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-dependent oxidoreductase - - - ko:K06955 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_7035_1 1121373.KB903626_gene3265 1.61e-13 65.1 2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_7035_2 266762.HQ36_04440 3.41e-14 74.7 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia,22WXH@171551|Porphyromonadaceae 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k141_21652_1 754476.Q7A_1935 1.06e-88 274.0 COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,1S2TH@1236|Gammaproteobacteria,4632U@72273|Thiotrichales 72273|Thiotrichales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_21652_2 626887.J057_18305 1.72e-22 99.8 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1SABB@1236|Gammaproteobacteria,467R8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component ttg2D - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_19577_1 1123367.C666_01370 2.08e-21 90.1 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,2KVFM@206389|Rhodocyclales 206389|Rhodocyclales S Peptidase M50 - - - - - - - - - - - - Peptidase_M50 k141_19577_2 349521.HCH_00871 1.33e-51 177.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,1S834@1236|Gammaproteobacteria,1XK62@135619|Oceanospirillales 135619|Oceanospirillales S secreted protein - - - - - - - - - - - - DUF1223 k141_19577_3 545276.KB898726_gene1022 2.22e-47 154.0 COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,1T11M@1236|Gammaproteobacteria,1X1AJ@135613|Chromatiales 135613|Chromatiales S Hemimethylated DNA-binding protein YccV like - - - ko:K11940 - - - - ko00000,ko03036 - - - YccV-like k141_5658_1 1288826.MSNKSG1_17366 5.98e-191 529.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,464CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L Exodeoxyribonuclease III crc - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_5658_2 1288826.MSNKSG1_17361 2.7e-143 405.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,4643W@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186 Pribosyltran k141_15592_1 1288826.MSNKSG1_08328 5e-234 647.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,464JE@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_217_1 1297865.APJD01000011_gene6837 4.49e-06 50.1 COG0745@1|root,COG2203@1|root,COG4191@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JR0R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Response regulator receiver - - - - - - - - - - - - CHASE3,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_217_2 653733.Selin_0950 1.07e-49 169.0 COG0628@1|root,COG0628@2|Bacteria 2|Bacteria D permease perM - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport k141_14186_1 1280952.HJA_03626 5.69e-114 345.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria 28211|Alphaproteobacteria F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_921_1 1232410.KI421420_gene3215 4.28e-64 207.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,42QBB@68525|delta/epsilon subdivisions,2WKEZ@28221|Deltaproteobacteria,43T67@69541|Desulfuromonadales 28221|Deltaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_921_2 479434.Sthe_3301 2.08e-08 54.7 COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia 189775|Thermomicrobia C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k141_218_1 395494.Galf_1546 5.5e-48 165.0 COG1879@1|root,COG1879@2|Bacteria,1MXJS@1224|Proteobacteria,2VJJZ@28216|Betaproteobacteria 28216|Betaproteobacteria G PFAM Periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_3741_1 1148.1653584 5.49e-10 60.8 COG2203@1|root,COG3614@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3614@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H6IG@1142|Synechocystis 1117|Cyanobacteria T CHASE - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,PAS_3,PAS_9 k141_15593_1 1397528.Q671_14960 2.16e-20 93.2 COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales 135619|Oceanospirillales L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_1639_1 1288826.MSNKSG1_04871 0.0 926.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,464T6@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) cyaB - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,MASE2 k141_1639_2 1288826.MSNKSG1_04876 1.88e-70 212.0 COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,4683B@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF962 k141_1639_3 1288826.MSNKSG1_04881 7.43e-60 188.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,4678D@72275|Alteromonadaceae 1236|Gammaproteobacteria C nitroreductase ydjA GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - - - - - - - - - - Nitroreductase k141_7938_1 1278309.KB907099_gene2704 5.09e-167 473.0 COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,1RRPT@1236|Gammaproteobacteria,1XH5A@135619|Oceanospirillales 135619|Oceanospirillales E Alcohol dehydrogenase GroES-like domain fdhA - 1.2.1.46 ko:K00148 ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200 - R00604 RC00188 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_3038_1 1278309.KB907100_gene2129 1.89e-50 175.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_9 k141_3038_2 1278309.KB907100_gene2130 4.9e-27 101.0 COG2960@1|root,COG2960@2|Bacteria 2|Bacteria M long-chain fatty acid transporting porin activity yqiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09806 - - - - ko00000 - - - BMFP k141_12802_6 1288826.MSNKSG1_12812 1.31e-247 681.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - - - - - - - - - - - GGDEF k141_12802_7 1288826.MSNKSG1_12807 0.0 932.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,4650Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0306 Phosphate sulphate permeases - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_12802_8 1288826.MSNKSG1_12802 5.47e-54 169.0 2E2KE@1|root,335N9@2|Bacteria,1NCMS@1224|Proteobacteria,1SE06@1236|Gammaproteobacteria,46C53@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12802_9 1288826.MSNKSG1_12797 0.0 1087.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,464QY@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0076 Glutamate decarboxylase and related PLP-dependent proteins gadB GO:0003674,GO:0003824,GO:0004068,GO:0016829,GO:0016830,GO:0016831 4.1.1.15 ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 M00027 R00261,R00489,R01682,R02466 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Pyridoxal_deC k141_12802_10 1288826.MSNKSG1_12792 7.88e-75 224.0 COG1550@1|root,COG1550@2|Bacteria,1N1MV@1224|Proteobacteria,1SAAS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09764 - - - - ko00000 - - - DUF503 k141_12802_11 1288826.MSNKSG1_12787 0.0 1125.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,4665Q@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases aidB GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K09456 - - - - ko00000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M k141_12802_12 1288826.MSNKSG1_12782 4.28e-134 381.0 COG1309@1|root,COG1309@2|Bacteria,1RJK5@1224|Proteobacteria,1S6NW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N k141_12802_13 1137799.GZ78_25930 0.000588 41.6 2EQ2V@1|root,33HP8@2|Bacteria,1NI2K@1224|Proteobacteria,1SHMN@1236|Gammaproteobacteria,1XMIX@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9281_1 743720.Psefu_0893 6.51e-43 150.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria,1YY3E@136845|Pseudomonas putida group 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_16987_1 1123504.JQKD01000003_gene598 2.15e-96 294.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,4ACCJ@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin k141_16987_2 743299.Acife_2674 9e-17 74.3 COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,1SE6E@1236|Gammaproteobacteria,2NCV4@225057|Acidithiobacillales 225057|Acidithiobacillales S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 k141_19758_1 1278309.KB907100_gene1848 8.52e-22 102.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_9 k141_10732_1 1026882.MAMP_00117 1.13e-152 436.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,460YS@72273|Thiotrichales 72273|Thiotrichales P Cation efflux family - - - - - - - - - - - - Cation_efflux k141_10732_2 1288826.MSNKSG1_04346 4.03e-266 755.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_7955_1 1122197.ATWI01000011_gene441 7.51e-57 180.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,4681G@72275|Alteromonadaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_7955_2 1122197.ATWI01000011_gene440 1.29e-57 182.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,467HF@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein - - - - - - - - - - - - ExbD k141_21881_1 1288826.MSNKSG1_18495 4.31e-197 574.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 k141_8623_1 627192.SLG_35320 1.69e-40 141.0 COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria 1224|Proteobacteria S LexA-binding, inner membrane-associated putative hydrolase ybcI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07038 - - - - ko00000 - - - YdjM k141_11430_1 1198232.CYCME_1314 1.44e-49 172.0 COG2960@1|root,COG2960@2|Bacteria,1NJYD@1224|Proteobacteria,1RYI7@1236|Gammaproteobacteria 1236|Gammaproteobacteria M long-chain fatty acid transporting porin activity - - - - - - - - - - - - - k141_4474_1 1049564.TevJSym_al00230 5.93e-94 283.0 COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,1RQHJ@1236|Gammaproteobacteria,1J7GZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G DeoC/LacD family aldolase fbaB GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640 DeoC k141_17698_1 1095769.CAHF01000011_gene2008 2.25e-132 389.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2VI37@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM FAD linked oxidase domain protein - - - - - - - - - - - - ALO,FAD_binding_4 k141_2306_2 1245471.PCA10_54730 1.2e-61 211.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1YDNK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H HemY protein N-terminus hemY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_2 k141_7224_1 745411.B3C1_18677 6.85e-142 428.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1J57N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k141_16988_2 314278.NB231_06126 4.81e-30 113.0 COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X2NE@135613|Chromatiales 135613|Chromatiales S mRNA catabolic process - - - - - - - - - - - - - k141_21217_1 1266914.ATUK01000012_gene155 6.88e-46 159.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_15599_2 477228.YO5_04032 6.69e-78 241.0 COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1YZWF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S NIF3 (NGG1p interacting factor 3) ybgI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - - - - - - - - - - NIF3 k141_16250_1 1288826.MSNKSG1_10318 5.88e-152 427.0 COG4380@1|root,COG4380@2|Bacteria,1R3WM@1224|Proteobacteria,1RSP7@1236|Gammaproteobacteria,468PI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative bacterial lipoprotein (DUF799) VY92_06375 - - - - - - - - - - - DUF799 k141_14194_1 1396858.Q666_06670 1.17e-31 121.0 COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria,466H7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family oprF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,OprF,TSP_3 k141_14194_2 1288826.MSNKSG1_09583 7.69e-78 232.0 COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,1T0MX@1236|Gammaproteobacteria,468NN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_14194_3 1288826.MSNKSG1_09588 6.5e-312 859.0 COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,1RQXQ@1236|Gammaproteobacteria,46434@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein tar - - ko:K03406,ko:K05875 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_14194_4 1288826.MSNKSG1_09593 0.0 1096.0 COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,464WC@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - - k141_14194_5 1288826.MSNKSG1_09598 0.0 1132.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,4661S@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - Collagen,DUF839 k141_14194_7 1288826.MSNKSG1_09608 2.65e-55 172.0 COG4568@1|root,COG4568@2|Bacteria,1NKDC@1224|Proteobacteria,1SUMY@1236|Gammaproteobacteria 1236|Gammaproteobacteria K rho-dependent transcription termination - - - ko:K19000 - - - - ko00000,ko03021 - - - - k141_14194_8 1288826.MSNKSG1_09613 1.16e-299 818.0 COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,46AIU@72275|Alteromonadaceae 1236|Gammaproteobacteria I Fatty acid desaturase - - 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase,Rubredoxin k141_14194_9 1288826.MSNKSG1_09618 1.19e-183 511.0 COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria,1RQ45@1236|Gammaproteobacteria,46CP5@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 k141_14194_10 1288826.MSNKSG1_09623 2.08e-123 367.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RPHJ@1236|Gammaproteobacteria,464JR@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bcd - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_4475_1 545276.KB898727_gene282 4.56e-43 140.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SCFA@1236|Gammaproteobacteria,1WYVX@135613|Chromatiales 135613|Chromatiales O Belongs to the sulfur carrier protein TusA family - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_12803_1 1123399.AQVE01000001_gene703 2.32e-28 111.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,463NF@72273|Thiotrichales 72273|Thiotrichales CH Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_12803_3 1121935.AQXX01000138_gene3179 3.84e-23 99.4 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XIR3@135619|Oceanospirillales 135619|Oceanospirillales H biosynthesis protein HemY hemY - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_7 k141_7956_1 1123237.Salmuc_02732 1.1e-29 123.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_1669_1 1049564.TevJSym_bi00190 1.07e-87 276.0 COG1509@1|root,COG1509@2|Bacteria,1NG2M@1224|Proteobacteria,1SR2C@1236|Gammaproteobacteria 1236|Gammaproteobacteria E lysine 2,3-aminomutase activity - - - - - - - - - - - - - k141_1669_2 768671.ThimaDRAFT_1764 2.03e-09 57.4 COG3439@1|root,COG3439@2|Bacteria,1RA8I@1224|Proteobacteria,1S34D@1236|Gammaproteobacteria,1WXZJ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 k141_19111_1 697282.Mettu_4224 1.39e-176 531.0 COG1196@1|root,COG1352@1|root,COG2201@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,1T2RH@1236|Gammaproteobacteria,1XE6G@135618|Methylococcales 135618|Methylococcales NT PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - - - - - - - - - - - CheB_methylest,CheR,CheR_N,PAS_10 k141_248_1 395493.BegalDRAFT_0232 9.68e-132 389.0 COG4651@1|root,COG4651@2|Bacteria,1QUQS@1224|Proteobacteria,1T21E@1236|Gammaproteobacteria,461MK@72273|Thiotrichales 72273|Thiotrichales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger k141_248_2 400668.Mmwyl1_1899 1.97e-11 61.2 COG0695@1|root,COG0695@2|Bacteria,1N0IY@1224|Proteobacteria,1SA4G@1236|Gammaproteobacteria,1XKKQ@135619|Oceanospirillales 135619|Oceanospirillales O Glutaredoxin - - - - - - - - - - - - GST_N_3,Glutaredoxin k141_9282_1 1123368.AUIS01000031_gene1431 2.51e-221 616.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase pucG - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k141_7225_1 367336.OM2255_09446 5.93e-59 188.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_7225_2 1208323.B30_02335 3.61e-51 167.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_12804_1 1121940.AUDZ01000012_gene908 1.84e-22 101.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XI7H@135619|Oceanospirillales 135619|Oceanospirillales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT k141_8624_1 713586.KB900536_gene2898 2.66e-23 97.8 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_8624_2 1255043.TVNIR_3429 5.56e-86 258.0 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales 135613|Chromatiales C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 k141_21883_1 653733.Selin_0676 0.000197 48.9 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator sdiA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032465,GO:0032467,GO:0032991,GO:0032993,GO:0043254,GO:0043565,GO:0044087,GO:0044089,GO:0044212,GO:0045787,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051302,GO:0051726,GO:0051781,GO:0060255,GO:0065007,GO:0080090,GO:0090068,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - ko:K07782,ko:K15852,ko:K18098,ko:K18304,ko:K19666,ko:K19731,ko:K19733,ko:K19734,ko:K20334,ko:K20540 ko02020,ko02024,ko02025,ko02026,map02020,map02024,map02025,map02026 M00644,M00769 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Autoind_bind,GerE k141_949_1 1288826.MSNKSG1_14557 5.59e-276 759.0 COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,1T1PC@1236|Gammaproteobacteria,46D4X@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily lplT - 2.3.1.40,6.2.1.20 ko:K05939,ko:K08227 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000,ko02000 2.A.1.42 - - MFS_1 k141_949_2 1288826.MSNKSG1_14562 4.17e-288 788.0 COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,1SYZV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2200 FOG EAL domain - - - - - - - - - - - - EAL k141_949_3 1288826.MSNKSG1_14567 7.87e-119 369.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_19759_1 1049564.TevJSym_ad00390 4.59e-21 89.7 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1J7WB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Tetrahydrodipicolinate N-succinyltransferase N-terminal dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0158 Hexapep,Hexapep_2,THDPS_N_2 k141_19759_2 95619.PM1_0217260 1.46e-95 290.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Succinyldiaminopimelate dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_3060_1 498211.CJA_1550 1.1e-06 60.8 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1QW2E@1224|Proteobacteria,1RPH1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L AAA domain - - - - - - - - - - - - AAA_11,AAA_12,DUF2726 k141_3060_2 1121441.AUCX01000009_gene2582 1.35e-14 77.8 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WNIK@28221|Deltaproteobacteria,2M9MA@213115|Desulfovibrionales 28221|Deltaproteobacteria N Membrane MotB of proton-channel complex MotA/MotB - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_3060_3 1307759.JOMJ01000003_gene1818 1.53e-19 87.4 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2M7ZH@213115|Desulfovibrionales 28221|Deltaproteobacteria N PFAM MotA TolQ ExbB proton channel motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_10734_1 1288826.MSNKSG1_02023 3.63e-139 394.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_249_1 1249627.D779_1881 3.06e-65 222.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_11432_1 1123368.AUIS01000005_gene486 1.52e-79 248.0 COG3395@1|root,COG3395@2|Bacteria,1QC4M@1224|Proteobacteria,1T7TD@1236|Gammaproteobacteria,2NBVC@225057|Acidithiobacillales 225057|Acidithiobacillales S Putative nucleotide-binding of sugar-metabolising enzyme - - - - - - - - - - - - DUF1357_C,DUF1537 k141_1671_1 1380387.JADM01000009_gene3237 2.1e-85 258.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XHX2@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_7957_1 1288826.MSNKSG1_07938 1.03e-220 632.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,464NY@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 PEP-utilizers,PEP-utilizers_C,PPDK_N k141_250_2 765913.ThidrDRAFT_1862 8.89e-30 117.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria,1WX76@135613|Chromatiales 135613|Chromatiales E lysine 2,3-aminomutase - - - - - - - - - - - - - k141_5121_1 1123517.JOMR01000001_gene1603 3.29e-107 317.0 COG0384@1|root,COG0384@2|Bacteria,1PHNM@1224|Proteobacteria,1RSZI@1236|Gammaproteobacteria,4634C@72273|Thiotrichales 72273|Thiotrichales S Phenazine biosynthesis-like protein - - 5.3.3.17 ko:K06998 ko00405,ko01130,ko02024,map00405,map01130,map02024 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - PhzC-PhzF k141_5121_2 509190.Cseg_3853 2.56e-19 87.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,2KF1I@204458|Caulobacterales 204458|Caulobacterales P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_17699_1 1288826.MSNKSG1_10588 1.37e-80 244.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,467BB@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k141_17699_2 1288826.MSNKSG1_10593 2.42e-103 301.0 COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,1S6R9@1236|Gammaproteobacteria,467ZJ@72275|Alteromonadaceae 1236|Gammaproteobacteria O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly ureE - - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N k141_13315_1 187272.Mlg_1865 1.11e-229 666.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_1452_1 935863.AWZR01000004_gene711 9.08e-18 87.4 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales 135614|Xanthomonadales P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_1452_2 713586.KB900536_gene1424 1.54e-31 112.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1WYUA@135613|Chromatiales 135613|Chromatiales G Phosphotransferase System - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_1452_3 454957.IA64_05650 1.24e-25 100.0 COG2893@1|root,COG2893@2|Bacteria,1NEI7@1224|Proteobacteria,1T14J@1236|Gammaproteobacteria,1X6E2@135614|Xanthomonadales 135614|Xanthomonadales G PTS system fructose IIA component family protein - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man k141_1452_4 1049564.TevJSym_ak00770 9.3e-111 328.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1J528@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Displays ATPase and GTPase activities rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_3540_1 1288826.MSNKSG1_08328 5.94e-23 95.9 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,464JE@72275|Alteromonadaceae 1236|Gammaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 k141_3540_2 1288826.MSNKSG1_08333 7.08e-177 494.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,464T4@72275|Alteromonadaceae 1236|Gammaproteobacteria N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 k141_3540_3 1288826.MSNKSG1_08338 1.97e-52 165.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,468JB@72275|Alteromonadaceae 1236|Gammaproteobacteria N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 k141_3540_4 1288826.MSNKSG1_08343 4.03e-164 461.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,464W5@72275|Alteromonadaceae 1236|Gammaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP k141_3540_5 1288826.MSNKSG1_08348 1.32e-68 209.0 COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,468FX@72275|Alteromonadaceae 1236|Gammaproteobacteria N COG3190 Flagellar biogenesis protein fliO - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO k141_16086_1 1288826.MSNKSG1_05636 3.83e-169 490.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1SM0Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT helical bimodular (HBM) domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_16086_2 1288826.MSNKSG1_05631 3.48e-118 342.0 COG1946@1|root,COG1946@2|Bacteria,1QTZJ@1224|Proteobacteria 1224|Proteobacteria I Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_3 k141_2145_2 525373.HMPREF0766_10205 6.29e-20 88.2 2DB9N@1|root,2Z7XI@2|Bacteria,4NGR0@976|Bacteroidetes,1IWBU@117747|Sphingobacteriia 976|Bacteroidetes S Glycosyl transferase family 90 lpsA - - - - - - - - - - - Glyco_transf_90 k141_7744_1 99598.Cal7507_0411 1.03e-41 142.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1HM7U@1161|Nostocales 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_7744_2 1163617.SCD_n02189 4.28e-109 328.0 COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria 28216|Betaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2 k141_7744_3 1163617.SCD_n01202 1.81e-127 383.0 COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2VJ4Z@28216|Betaproteobacteria 28216|Betaproteobacteria P TrkA-N domain protein - - - - - - - - - - - - Ion_trans_2,TrkA_N k141_20311_2 1278309.KB907100_gene1943 2.6e-279 768.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIJV@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_18897_1 717785.HYPMC_2668 9.32e-12 70.9 COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,2TV9N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GDYXXLXY protein - - - - - - - - - - - - GDYXXLXY k141_4245_1 1120950.KB892707_gene4871 5.91e-05 47.8 COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4DP3M@85009|Propionibacteriales 201174|Actinobacteria Q Flavin containing amine oxidoreductase crtI2 - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - Amino_oxidase k141_4245_2 765914.ThisiDRAFT_0271 1.25e-75 236.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RNRI@1236|Gammaproteobacteria,1WYA5@135613|Chromatiales 135613|Chromatiales I Squalene phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY k141_16098_1 998674.ATTE01000001_gene2757 2.74e-97 306.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales 72273|Thiotrichales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N k141_17475_1 1232410.KI421425_gene1552 2.02e-85 284.0 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales 28221|Deltaproteobacteria M OmpA family - - - - - - - - - - - - OmpA k141_21033_1 1278309.KB907105_gene1469 4.58e-52 169.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1XJAQ@135619|Oceanospirillales 135619|Oceanospirillales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_21033_2 1278309.KB907105_gene1468 3.96e-143 405.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1XJ87@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k141_21033_3 1278309.KB907105_gene1467 1.09e-114 337.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1XJZQ@135619|Oceanospirillales 135619|Oceanospirillales G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin k141_13338_1 1237149.C900_04439 8.11e-138 414.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia 976|Bacteroidetes EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_18898_1 1123073.KB899241_gene2709 8.72e-30 113.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1X2XT@135614|Xanthomonadales 135614|Xanthomonadales KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07660 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k141_18898_2 1278309.KB907108_gene1620 1.29e-37 128.0 COG3212@1|root,COG3212@2|Bacteria 2|Bacteria T peptidase Z012_07375 - - - - - - - - - - - PepSY k141_4246_1 1239962.C943_01621 1.65e-77 254.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia 976|Bacteroidetes EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_771_1 857087.Metme_0914 3.65e-13 70.5 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria U General secretion pathway protein J gspJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_771_2 1049564.TevJSym_av00300 9.99e-30 111.0 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,1J78U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG2165 Type II secretory pathway, pseudopilin PulG gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_3564_1 454957.IA64_02345 6.12e-56 188.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1X3U0@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar motor protein motB2 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k141_3564_2 987059.RBXJA2T_14526 2.69e-27 108.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,1KJE3@119065|unclassified Burkholderiales 28216|Betaproteobacteria N MotA/TolQ/ExbB proton channel family motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_19589_1 1117647.M5M_00820 2.09e-12 67.4 COG1307@1|root,COG1307@2|Bacteria,1R5M9@1224|Proteobacteria,1S6F7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lipid binding - - - - - - - - - - - - DegV k141_19589_2 317025.Tcr_0280 7.18e-21 90.9 COG3193@1|root,COG3193@2|Bacteria,1RK4B@1224|Proteobacteria,1S256@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_19589_3 2340.JV46_04650 3.28e-56 186.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos k141_2156_1 986075.CathTA2_1845 7.44e-11 61.2 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran k141_2156_2 187272.Mlg_1138 9.78e-95 284.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1WWXS@135613|Chromatiales 135613|Chromatiales P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU k141_2156_3 379731.PST_3004 1.4e-151 439.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1Z0Y3@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_2156_4 317025.Tcr_0464 5.43e-30 117.0 COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria,4632G@72273|Thiotrichales 72273|Thiotrichales M Gram-negative porin - - - - - - - - - - - - Porin_4 k141_7762_1 156889.Mmc1_2139 5.12e-108 321.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component dctP - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP k141_6338_1 1238450.VIBNISOn1_1710009 2.7e-168 474.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XT40@135623|Vibrionales 135623|Vibrionales F Belongs to the RimK family rimK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k141_6338_2 1279019.ARQK01000039_gene448 8.15e-56 179.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1WYD4@135613|Chromatiales 135613|Chromatiales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_6338_3 1167006.UWK_02198 4.15e-22 100.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42MB2@68525|delta/epsilon subdivisions,2WJAF@28221|Deltaproteobacteria,2MN15@213118|Desulfobacterales 28221|Deltaproteobacteria M POTRA domain TamA domain 1 - - - ko:K07277,ko:K07278 - - - - ko00000,ko02000,ko03029 1.B.33,1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_14027_1 1179773.BN6_21530 2.24e-22 102.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EABX@85010|Pseudonocardiales 201174|Actinobacteria M Insecticide toxin TcdB middle/N-terminal region - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB,TcdB_toxin_midN k141_1465_1 1122201.AUAZ01000023_gene3016 6.61e-113 332.0 COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,1RPF3@1236|Gammaproteobacteria,468GI@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K19338 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_16807_1 105559.Nwat_0440 1.05e-111 334.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales 135613|Chromatiales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_16807_2 748658.KB907316_gene520 1.31e-61 206.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_21660_1 1162668.LFE_1237 1.74e-19 89.4 COG0412@1|root,COG0412@2|Bacteria,3J1B9@40117|Nitrospirae 40117|Nitrospirae Q Alpha/beta hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_21660_2 1123487.KB892849_gene277 4.74e-13 67.0 COG2149@1|root,COG2149@2|Bacteria,1NGFR@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF202) - - - ko:K00389 - - - - ko00000 - - - DUF202 k141_11268_1 880071.Fleli_4073 1.41e-78 246.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,47JNE@768503|Cytophagia 976|Bacteroidetes E argininosuccinate synthase argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth k141_10535_1 1288826.MSNKSG1_14657 4.02e-112 330.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,466CC@72275|Alteromonadaceae 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k141_10535_2 1288826.MSNKSG1_14662 0.0 1217.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,464Q3@72275|Alteromonadaceae 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_21035_1 1122197.ATWI01000011_gene436 6.14e-75 246.0 COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 k141_5681_1 396588.Tgr7_0458 1.48e-17 94.7 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1WYS8@135613|Chromatiales 135613|Chromatiales KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - HAMP,HEAT_2,Pkinase,sCache_3_2 k141_15437_1 323261.Noc_2483 3.08e-126 378.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,1WW64@135613|Chromatiales 135613|Chromatiales M Belongs to the mannose-6-phosphate isomerase type 2 family - - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase k141_20314_1 573061.Clocel_3917 1.09e-25 104.0 COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,247MM@186801|Clostridia,36GKW@31979|Clostridiaceae 186801|Clostridia E TIGRFAM histidinol phosphate phosphatase HisJ hisK - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP k141_12625_1 1288826.MSNKSG1_15711 2.95e-299 818.0 COG0149@1|root,COG3707@1|root,COG0149@2|Bacteria,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,1RMQG@1236|Gammaproteobacteria,464HH@72275|Alteromonadaceae 1236|Gammaproteobacteria K Nitrate-and nitrite-responsive positive regulator nasR - - - - - - - - - - - ANTAR,NIT k141_12625_2 1288826.MSNKSG1_15716 1.51e-199 553.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,46520@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component nasD - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran k141_12625_3 1288826.MSNKSG1_15721 1.28e-230 635.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,46587@72275|Alteromonadaceae 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_12625_4 1288826.MSNKSG1_15726 0.0 946.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_12625_5 1288826.MSNKSG1_15731 0.0 1702.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,465G2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_12625_6 1288826.MSNKSG1_15736 3.39e-160 449.0 2F7YD@1|root,340C8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_12625_7 1288826.MSNKSG1_15751 5.11e-126 358.0 COG3157@1|root,COG3157@2|Bacteria,1MXFB@1224|Proteobacteria,1RNKQ@1236|Gammaproteobacteria,466T9@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG3157 Hemolysin-coregulated protein hcp - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k141_12625_8 1288826.MSNKSG1_15756 0.0 1434.0 COG2199@1|root,COG4191@1|root,COG2199@2|Bacteria,COG4191@2|Bacteria,1RE50@1224|Proteobacteria,1S3P4@1236|Gammaproteobacteria,4654C@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1 k141_12625_9 1288826.MSNKSG1_15761 2.49e-180 502.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,466JN@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE k141_12625_10 1288826.MSNKSG1_15766 5.94e-278 759.0 28KPT@1|root,2ZA7X@2|Bacteria,1MXE6@1224|Proteobacteria,1RYVK@1236|Gammaproteobacteria,465CZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT k141_12625_11 1288826.MSNKSG1_15771 0.0 976.0 COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,1RMKH@1236|Gammaproteobacteria,466AW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the amidase family nylA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_12625_13 1288826.MSNKSG1_15781 2.84e-150 430.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,466KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_5682_1 313606.M23134_03071 1.46e-49 181.0 COG1629@1|root,COG1629@2|Bacteria,4PM06@976|Bacteroidetes,47Y21@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,TonB_dep_Rec k141_15438_1 864069.MicloDRAFT_00061290 2.68e-09 60.8 COG2270@1|root,COG2270@2|Bacteria,1QVPF@1224|Proteobacteria,2TWJC@28211|Alphaproteobacteria,1JY30@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Transmembrane secretion effector - - - - - - - - - - - - MFS_3 k141_15438_2 1188256.BASI01000002_gene3414 3.55e-29 116.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,3FCK5@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC k141_16809_1 1410676.JNKL01000005_gene319 5.08e-19 84.3 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1Y3YM@135624|Aeromonadales 135624|Aeromonadales J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e k141_16809_2 1026882.MAMP_01367 3.61e-49 174.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales 72273|Thiotrichales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_20315_1 1265502.KB905969_gene1242 5.08e-56 194.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria 28216|Betaproteobacteria EGP Major facilitator Superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_12627_1 345341.KUTG_00451 1.79e-29 119.0 COG3227@1|root,COG3511@1|root,COG3227@2|Bacteria,COG3511@2|Bacteria,2H8MY@201174|Actinobacteria,4E20J@85010|Pseudonocardiales 201174|Actinobacteria M Phosphoesterase family - - 3.1.3.64 ko:K21302 ko00562,ko01100,ko05152,map00562,map01100,map05152 - - - ko00000,ko00001,ko01000 - - - F5_F8_type_C,Glyco_hydro_46,Phosphoesterase k141_11939_1 1278309.KB907099_gene2753 5.66e-246 685.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,1XHPP@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha k141_17477_1 1296415.JACC01000007_gene2472 1.79e-06 53.5 COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia,2YI6W@290174|Aquimarina 976|Bacteroidetes G Polysaccharide deacetylase pgdA_1 - - - - - - - - - - - Polysacc_deac_1 k141_16099_1 272943.RSP_0461 7.84e-36 133.0 COG0845@1|root,COG0845@2|Bacteria,1MXU4@1224|Proteobacteria,2TUXB@28211|Alphaproteobacteria,1FBH3@1060|Rhodobacter 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_11269_1 87626.PTD2_18680 1.62e-39 152.0 COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria,1RRQ9@1236|Gammaproteobacteria,2Q1DI@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - OMP_b-brl_3,Plug,TonB_dep_Rec k141_10536_1 59538.XP_005964165.1 1.15e-15 77.0 COG0021@1|root,KOG0523@2759|Eukaryota 2759|Eukaryota G transketolase activity DXS - 2.2.1.1,2.2.1.7 ko:K00615,ko:K01662 ko00030,ko00710,ko00730,ko00900,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map00730,map00900,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00096,M00165,M00167 R01067,R01641,R01830,R05636,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C,Transketolase_N k141_10536_2 243233.MCA0818 9.37e-31 117.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XDRY@135618|Methylococcales 135618|Methylococcales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_18900_1 870187.Thini_1080 5.78e-96 287.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_21036_1 472759.Nhal_2084 7.03e-33 132.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales 135613|Chromatiales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C k141_2157_1 866536.Belba_0300 2.94e-115 361.0 COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 k141_13340_1 396588.Tgr7_0663 5.34e-41 145.0 COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WVYJ@135613|Chromatiales 135613|Chromatiales T signal transduction protein - - - - - - - - - - - - HDOD k141_13340_2 1123401.JHYQ01000015_gene1412 6.25e-42 141.0 2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,1S97C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_62_1 367336.OM2255_13494 9.85e-68 218.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria 28211|Alphaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k141_12096_5 517433.PanABDRAFT_3691 1.05e-32 129.0 28N2X@1|root,2ZB8P@2|Bacteria,1R4KJ@1224|Proteobacteria,1T3E3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S sty2063 SWALL Q8Z5Z8 (EMBL AL627272) (262 aa) fasta scores E() 1.5e-07, 24.43 id in 266 aa, and to Escherichia coli O157 H7 - - - - - - - - - - - - - k141_18361_1 596153.Alide_2766 9.21e-59 189.0 COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria,4ADJ0@80864|Comamonadaceae 28216|Betaproteobacteria Q Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 k141_3732_1 1051646.VITU9109_13671 2.2e-39 143.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria,1Y2N9@135623|Vibrionales 135623|Vibrionales V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase k141_3732_2 314292.VAS14_03698 4.54e-28 109.0 COG2862@1|root,COG2862@2|Bacteria,1RE6N@1224|Proteobacteria,1S4EE@1236|Gammaproteobacteria,1XXHM@135623|Vibrionales 135623|Vibrionales S Uncharacterized protein family, UPF0114 - - - - - - - - - - - - UPF0114 k141_13480_1 292.DM42_3917 8.54e-52 182.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,1K486@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.6 ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_19087_1 519989.ECTPHS_06927 2.74e-13 70.5 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k141_19087_2 713586.KB900536_gene3023 4.2e-52 169.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1WY06@135613|Chromatiales 135613|Chromatiales I Cyclase dehydrase - - - - - - - - - - - - Polyketide_cyc k141_19087_3 1249627.D779_0581 7.02e-13 64.7 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1WYYA@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0125 (RnfH) family - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH k141_19728_1 270374.MELB17_20861 4.18e-107 322.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4641G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_19728_2 930169.B5T_03767 4.11e-48 169.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XHW7@135619|Oceanospirillales 135619|Oceanospirillales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_15585_1 2340.JV46_26720 1.1e-102 314.0 COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,1JARP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Nickel-dependent hydrogenase hydB - 1.12.5.1,1.12.99.6 ko:K05922,ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases k141_14180_1 1120953.AUBH01000001_gene848 4.82e-05 48.1 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Response_reg k141_9251_1 1278309.KB907100_gene2112 7.74e-262 725.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,1XM2S@135619|Oceanospirillales 135619|Oceanospirillales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_9251_2 207954.MED92_06876 3.32e-47 155.0 COG0394@1|root,COG0394@2|Bacteria,1NNNQ@1224|Proteobacteria,1SI2S@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Low molecular weight phosphatase family - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc k141_914_2 396588.Tgr7_1965 2.34e-17 80.9 COG2882@1|root,COG2882@2|Bacteria,1NHU4@1224|Proteobacteria,1SGCB@1236|Gammaproteobacteria,1WZS6@135613|Chromatiales 135613|Chromatiales N Flagellar FliJ protein - - - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ k141_5095_1 1278309.KB907099_gene2718 3.26e-76 235.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1XK16@135619|Oceanospirillales 135619|Oceanospirillales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k141_5095_2 1278309.KB907099_gene2719 1.41e-218 629.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XIGX@135619|Oceanospirillales 135619|Oceanospirillales C formate dehydrogenase fdsA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_4435_1 243277.VC_2555 6.08e-28 108.0 COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S9ZC@1236|Gammaproteobacteria,1Y2NN@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF3299) - - - ko:K09950 - - - - ko00000 - - - DUF3299 k141_12793_1 1237149.C900_03236 2.53e-68 216.0 COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47PMC@768503|Cytophagia 976|Bacteroidetes P K -dependent Na Ca exchanger yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_7922_2 1298593.TOL_0955 1.23e-47 166.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XING@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k141_16952_1 1288826.MSNKSG1_01413 1.99e-107 316.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,467NW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_2496,iEC042_1314.EC042_4342,iECOK1_1307.ECOK1_4443,iECS88_1305.ECS88_4426,iPC815.YPO3909,iUMN146_1321.UM146_20110,iUTI89_1310.UTI89_C4562 Asp_Glu_race k141_16952_2 1288826.MSNKSG1_01418 3.35e-244 670.0 COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria,1S7E5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised conserved protein (DUF2156) - - - - - - - - - - - - DUF2156 k141_16952_3 1288826.MSNKSG1_01423 1.21e-158 444.0 COG0500@1|root,COG2226@2|Bacteria,1R7VM@1224|Proteobacteria,1SKGK@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methylase involved in ubiquinone menaquinone biosynthesis - - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_25 k141_16952_4 1288826.MSNKSG1_01428 0.0 1253.0 COG0745@1|root,COG5001@1|root,COG0745@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4643S@72275|Alteromonadaceae 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_21844_1 1123368.AUIS01000023_gene933 1.35e-102 326.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 k141_7195_1 1158292.JPOE01000002_gene2265 4.95e-30 114.0 COG2847@1|root,COG2847@2|Bacteria,1N3BG@1224|Proteobacteria,2VX2P@28216|Betaproteobacteria,1KPK2@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_18362_1 1168065.DOK_06255 1.01e-89 292.0 COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1J7QM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Pfam:AHS1 uca - 6.3.4.6 ko:K01941 ko00220,ko00791,ko01100,map00220,map00791,map01100 - R00774 RC00378 ko00000,ko00001,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D k141_13481_1 675806.VII_002799 3.2e-13 74.3 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RNRU@1236|Gammaproteobacteria,1XU1F@135623|Vibrionales 135623|Vibrionales S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_17663_1 1453501.JELR01000002_gene152 0.000163 52.4 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_16232_2 754476.Q7A_2877 2.94e-260 719.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,45ZSD@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k141_16232_3 1249627.D779_2056 2.59e-13 67.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, E subunit - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_915_1 305900.GV64_18845 3.58e-52 169.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1XJJI@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ k141_209_1 1278309.KB907106_gene1257 1.39e-119 344.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XH9C@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A k141_209_2 1278309.KB907106_gene1256 0.0 894.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1XHMS@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C k141_209_3 1278309.KB907106_gene1255 1.51e-35 124.0 29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,1S4I9@1236|Gammaproteobacteria,1XJQY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_19729_1 1278309.KB907100_gene2174 2.29e-27 112.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K21021 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - CHASE8,EAL,GAF,GAF_2,GGDEF,HAMP,PAS_3,PAS_9 k141_9253_1 1234364.AMSF01000088_gene2737 6.21e-97 303.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1X3M6@135614|Xanthomonadales 135614|Xanthomonadales C NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_13482_1 1229172.JQFA01000004_gene602 6.9e-62 207.0 COG1283@1|root,COG1283@2|Bacteria,1G2NY@1117|Cyanobacteria 1117|Cyanobacteria P Na Pi-cotransporter family protein - - - - - - - - - - - - Na_Pi_cotrans k141_18363_1 1232683.ADIMK_0165 2.34e-40 145.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,463YB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_18363_2 1232683.ADIMK_0166 2.42e-50 164.0 2BXMA@1|root,2ZBQ1@2|Bacteria,1MXZ1@1224|Proteobacteria,1SAQB@1236|Gammaproteobacteria,468C6@72275|Alteromonadaceae 1236|Gammaproteobacteria S (twin-arginine translocation) pathway signal - - - - - - - - - - - - Gluconate_2-dh3 k141_20483_1 1198452.Jab_2c01530 3.95e-47 162.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,2VPDS@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_20483_2 1131553.JIBI01000030_gene2444 2.29e-78 237.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,37318@32003|Nitrosomonadales 28216|Betaproteobacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP k141_20483_3 323848.Nmul_A2159 5.88e-26 99.0 COG1531@1|root,COG1531@2|Bacteria,1N7PM@1224|Proteobacteria,2W6WU@28216|Betaproteobacteria,374JG@32003|Nitrosomonadales 28216|Betaproteobacteria AJ Protein of unknown function (DUF504) - - - - - - - - - - - - DUF504 k141_20483_4 1227349.C170_20065 3.88e-09 59.7 COG0001@1|root,COG0318@1|root,COG1020@1|root,COG3321@1|root,COG0001@2|Bacteria,COG0318@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae 91061|Bacilli Q Non-ribosomal peptide synthetase modules and related proteins nrsA - - - - - - - - - - - AMP-binding,AMP-binding_C,Aminotran_3,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,ketoacyl-synt k141_5097_2 1278309.KB907108_gene1556 4.92e-53 175.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XH6Q@135619|Oceanospirillales 135619|Oceanospirillales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k141_19088_1 1288826.MSNKSG1_13182 1.81e-202 585.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RX68@1236|Gammaproteobacteria,46688@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2203 FOG GAF domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3 k141_7924_1 768671.ThimaDRAFT_4194 2.61e-59 192.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1WWIU@135613|Chromatiales 135613|Chromatiales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_21210_1 95619.PM1_0211820 1.93e-18 90.1 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_11426_1 1317124.DW2_17370 2.66e-53 184.0 28KGS@1|root,2ZA2F@2|Bacteria,1RD5S@1224|Proteobacteria,2U7YS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - TniQ k141_16245_1 395493.BegalDRAFT_0086 8.13e-64 222.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,460BV@72273|Thiotrichales 72273|Thiotrichales E Bacterial NAD-glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k141_3054_1 1288826.MSNKSG1_13892 6.23e-249 684.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,464MK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_3054_2 1288826.MSNKSG1_13887 4.28e-67 204.0 COG2913@1|root,COG2913@2|Bacteria,1N44J@1224|Proteobacteria,1SSX3@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SmpA_OmlA k141_3054_3 1288826.MSNKSG1_13882 5.75e-247 681.0 COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,4641T@72275|Alteromonadaceae 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin k141_3054_4 1288826.MSNKSG1_13877 4.89e-130 371.0 COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1T10H@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N k141_944_1 765910.MARPU_05390 9.97e-13 72.8 COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1WWAJ@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c k141_3753_1 1049564.TevJSym_an00450 8.37e-169 483.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J8WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD k141_19105_1 1278309.KB907100_gene2003 2.6e-305 838.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XIJZ@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_19105_2 1278309.KB907100_gene2004 7.65e-88 265.0 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1S7YD@1236|Gammaproteobacteria,1XREV@135619|Oceanospirillales 135619|Oceanospirillales D Sporulation related domain - - - - - - - - - - - - SPOR k141_19105_3 1278309.KB907100_gene2005 3.49e-111 321.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1XIAU@135619|Oceanospirillales 135619|Oceanospirillales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome k141_19105_4 1278309.KB907100_gene2006 1.37e-206 579.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XI7F@135619|Oceanospirillales 135619|Oceanospirillales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small k141_15594_1 65672.G4U3G3 7.32e-45 160.0 COG1622@1|root,KOG4767@2759|Eukaryota,38FF8@33154|Opisthokonta,3NUKK@4751|Fungi,3UZNV@5204|Basidiomycota,22BUM@155619|Agaricomycetes 4751|Fungi C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 cox2 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600 - ko:K02261 ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.11,3.D.4.7,3.D.4.8 - - COX2,COX2_TM k141_15594_2 4896.SPMIT.06.1 1.15e-127 403.0 COG3344@1|root,KOG4768@2759|Eukaryota,39UKU@33154|Opisthokonta,3P0IZ@4751|Fungi,3QZIF@4890|Ascomycota 4751|Fungi A encoded by a mobile group II intron within the mitochondrial COX1 gene - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003964,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006278,GO:0006310,GO:0006314,GO:0006315,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - - - - - - - - - - Intron_maturas2,RVT_1 k141_15594_3 1259795.ARJK01000003_gene826 5.59e-26 101.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,42GED@68295|Thermoanaerobacterales 186801|Clostridia J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_15594_5 983920.Y88_0226 2.6e-126 375.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2K177@204457|Sphingomonadales 204457|Sphingomonadales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_2299_1 83219.PM02_15060 2.57e-118 369.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2TQJW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narZ - 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding,Nitr_red_alph_N k141_9965_1 744979.R2A130_3023 2.62e-109 329.0 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,2TR25@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Xanthine uracil - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease k141_18383_1 396588.Tgr7_0130 1.65e-28 107.0 2E1SU@1|root,32X2N@2|Bacteria,1N4HW@1224|Proteobacteria,1SAEX@1236|Gammaproteobacteria,1X167@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_18383_2 948106.AWZT01000051_gene3094 2.21e-78 244.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,1JZXD@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM k141_5117_1 1278309.KB907103_gene1156 2.06e-16 77.8 2DMMJ@1|root,32SFS@2|Bacteria,1N3DK@1224|Proteobacteria,1T003@1236|Gammaproteobacteria,1XM1Z@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5117_2 1278309.KB907103_gene1157 2.88e-67 208.0 2AHZA@1|root,318CM@2|Bacteria,1RHH8@1224|Proteobacteria,1S827@1236|Gammaproteobacteria,1XJVY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_9278_1 1286106.MPL1_12943 1.34e-47 155.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales 72273|Thiotrichales FG Histidine triad (HIT) protein - - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT k141_9278_2 1123517.JOMR01000001_gene3 5.35e-17 75.5 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,461D2@72273|Thiotrichales 72273|Thiotrichales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k141_7215_1 1278309.KB907100_gene2135 2.4e-58 192.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,1RNIW@1236|Gammaproteobacteria,1XHPY@135619|Oceanospirillales 135619|Oceanospirillales E Acetylornithine deacetylase - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_7215_2 1278309.KB907100_gene2137 8.21e-25 100.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XHNI@135619|Oceanospirillales 135619|Oceanospirillales E arginine N-succinyltransferase - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_3754_1 1211115.ALIQ01000136_gene1255 6.06e-32 117.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,3NBCC@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Cytochrome c cycA - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C k141_16984_2 2340.JV46_03550 1.06e-54 187.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1J4RR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990 Transket_pyr,Transketolase_C,Transketolase_N k141_21211_1 1122599.AUGR01000021_gene3193 1.42e-169 486.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RP5H@1236|Gammaproteobacteria,1XHYM@135619|Oceanospirillales 135619|Oceanospirillales P Nitrate nitrite transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_17694_1 1449351.RISW2_20145 1.52e-114 356.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,4KM41@93682|Roseivivax 28211|Alphaproteobacteria C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_7216_1 1348114.OM33_06955 8.95e-38 134.0 COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,2Q01F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair mutH GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - ko:K03573 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutH k141_11427_1 1288826.MSNKSG1_08718 1.25e-178 502.0 COG0451@1|root,COG1898@1|root,COG0451@2|Bacteria,COG1898@2|Bacteria,1MXGB@1224|Proteobacteria,1RSK7@1236|Gammaproteobacteria,46A1X@72275|Alteromonadaceae 1236|Gammaproteobacteria GM NAD dependent epimerase/dehydratase family fnlB - 1.1.1.367 ko:K19068 - - - - ko00000,ko01000 - - - Epimerase k141_18384_1 1288826.MSNKSG1_01608 4.19e-54 174.0 COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,467B2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Nitroreductase family nfnB - 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase k141_18384_2 1288826.MSNKSG1_01603 3.52e-39 137.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RR7U@1236|Gammaproteobacteria,464ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_5118_1 748247.AZKH_3055 5.36e-31 122.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales 206389|Rhodocyclales CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_3221_1 631454.N177_1535 1.39e-90 273.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,1JNBJ@119043|Rhodobiaceae 28211|Alphaproteobacteria S AAA domain (dynein-related subfamily) coxD - - - - - - - - - - - AAA_5 k141_13648_1 225937.HP15_2393 1.84e-42 147.0 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,464CM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2089 Sialic acid synthase neuB - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k141_13648_2 225937.HP15_2392 1.43e-157 446.0 2925F@1|root,2ZPQC@2|Bacteria,1N5YX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - PhyH k141_2471_1 1278309.KB907099_gene2371 8.89e-73 231.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1XHH2@135619|Oceanospirillales 135619|Oceanospirillales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_2471_2 1129794.C427_5045 1.17e-39 142.0 2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria,46A4G@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k141_2471_3 1278309.KB907099_gene2370 3.68e-100 291.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1XKP7@135619|Oceanospirillales 135619|Oceanospirillales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k141_2471_4 1278309.KB907099_gene2369 0.0 1159.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1XIDU@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_2471_5 1278309.KB907099_gene2368 2.77e-112 326.0 COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,1S8AC@1236|Gammaproteobacteria,1XJHZ@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - TetR_N,WHG k141_2471_6 1122201.AUAZ01000023_gene3020 2.91e-117 347.0 COG0583@1|root,COG0583@2|Bacteria,1RA6G@1224|Proteobacteria,1S6QJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_5947_1 1278309.KB907099_gene2635 7.88e-33 114.0 2EPBF@1|root,33GY7@2|Bacteria,1NHWE@1224|Proteobacteria,1SHUW@1236|Gammaproteobacteria,1XMPW@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_1814_1 1235689.K4NWH1_9CAUD 9.48e-31 124.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k141_415_1 225849.swp_2731 6.15e-15 80.1 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,2QB7X@267890|Shewanellaceae 1236|Gammaproteobacteria M rhs family - - - - - - - - - - - - RHS_repeat k141_21337_1 713586.KB900536_gene226 2.5e-31 110.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria 1224|Proteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a k141_21337_2 1255043.TVNIR_1527 1.95e-31 110.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales 135613|Chromatiales K PFAM Cold-shock protein, DNA-binding - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_21337_3 1379698.RBG1_1C00001G0062 7.65e-57 186.0 COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT k141_8739_1 713586.KB900536_gene3079 7.94e-70 230.0 COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1WX1A@135613|Chromatiales 135613|Chromatiales T Putative nucleotidyltransferase substrate binding domain - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_11548_1 1353537.TP2_03240 1.75e-09 58.2 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,2XM99@285107|Thioclava 28211|Alphaproteobacteria L Elongator protein 3, MiaB family, Radical SAM MA20_42330 - - - - - - - - - - - Radical_SAM k141_11548_2 626887.J057_03155 6.5e-62 213.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4654N@72275|Alteromonadaceae 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS k141_17839_1 1122619.KB892300_gene1005 1.43e-16 77.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,3T1TG@506|Alcaligenaceae 28216|Betaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k141_17839_2 349521.HCH_06216 1.68e-49 163.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_5948_1 95619.PM1_0221865 2.3e-70 226.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ATPase related to the helicase subunit of the Holliday junction resolvase rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_5278_1 1232683.ADIMK_0775 9.83e-191 538.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1S12D@1236|Gammaproteobacteria,469ID@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) - - - - - - - - - - - - DUF1329 k141_1117_1 214092.YPO2588 7.6e-85 270.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,41F0P@629|Yersinia 1236|Gammaproteobacteria V ABC transporter transmembrane region atmA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_2472_1 580332.Slit_1671 6.62e-63 210.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales 28216|Betaproteobacteria C Oxidoreductase FAD-binding domain protein ascD - 1.17.1.1 ko:K00523,ko:K18248 ko00520,ko00627,ko01120,map00520,map00627,map01120 M00637 R00823,R00825,R03391,R03392 RC00192,RC00230 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_19266_2 1249627.D779_1800 3.39e-37 131.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1WXA6@135613|Chromatiales 135613|Chromatiales H riboflavin synthase, alpha subunit - - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k141_8137_1 1279019.ARQK01000020_gene2437 3.81e-57 187.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_7360_2 1192034.CAP_1824 5.44e-20 86.3 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2YV1X@29|Myxococcales 28221|Deltaproteobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 k141_7360_3 1122613.ATUP01000001_gene293 1.13e-32 119.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,43XNF@69657|Hyphomonadaceae 28211|Alphaproteobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k141_7360_6 1117108.PAALTS15_12372 1.11e-40 146.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,26SND@186822|Paenibacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_5279_1 1286106.MPL1_03935 3.71e-36 131.0 28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,1RNKD@1236|Gammaproteobacteria,461V1@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_5279_2 1123237.Salmuc_04353 8.79e-10 58.2 COG3409@1|root,COG3409@2|Bacteria,1RAFU@1224|Proteobacteria,2U9U7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - PG_binding_1,Peptidase_M15_4 k141_14296_1 1049564.TevJSym_at00030 1.49e-99 302.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14296_2 768671.ThimaDRAFT_3218 1.53e-92 284.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales 135613|Chromatiales U Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_8740_1 1282360.ABAC460_01310 5.42e-21 88.6 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2KGN6@204458|Caulobacterales 204458|Caulobacterales C 2Fe-2S -binding domain protein - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k141_8740_2 1121381.JNIV01000016_gene1742 0.000118 47.4 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k141_20635_1 156889.Mmc1_1089 5.4e-134 389.0 COG0840@1|root,COG0840@2|Bacteria 2|Bacteria NT transmembrane signaling receptor activity - - - - - - - - - - - - 4HB_MCP_1,dCache_1,sCache_3_3 k141_20635_2 658187.LDG_7096 2.02e-18 87.4 COG1670@1|root,COG1708@1|root,COG4994@1|root,COG1670@2|Bacteria,COG1708@2|Bacteria,COG4994@2|Bacteria,1QYJI@1224|Proteobacteria,1T3QY@1236|Gammaproteobacteria,1JE53@118969|Legionellales 118969|Legionellales J Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Acetyltransf_10 k141_20635_3 298386.PBPRB0651 4.44e-84 256.0 COG2010@1|root,COG2010@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_21338_1 946483.Cenrod_1791 1.49e-24 102.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,2VI4E@28216|Betaproteobacteria,4A9SV@80864|Comamonadaceae 28216|Betaproteobacteria T Two component signalling adaptor domain cheV1-2 - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_21338_2 765913.ThidrDRAFT_2728 5.68e-39 139.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1WW26@135613|Chromatiales 135613|Chromatiales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_19892_1 1163617.SCD_n02267 1.99e-63 215.0 COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,1MU1B@1224|Proteobacteria,2WEGQ@28216|Betaproteobacteria 28216|Betaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_11 k141_5949_1 76114.ebA4491 5.83e-57 189.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,2KUSX@206389|Rhodocyclales 206389|Rhodocyclales C FAD binding glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_5949_2 511.JT27_03480 7.33e-25 102.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,3T26U@506|Alcaligenaceae 28216|Betaproteobacteria C Glycolate oxidase subunit glcD - 1.1.2.4,1.1.3.15,1.1.5.12 ko:K00102,ko:K00104,ko:K03777 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 - R00197,R00475,R00704,R11591 RC00042,RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_15757_1 1278309.KB907104_gene968 2.1e-126 365.0 2DUFW@1|root,33QG9@2|Bacteria,1R2X8@1224|Proteobacteria,1T5ZH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_15757_2 1278309.KB907104_gene967 5.16e-163 459.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XH8W@135619|Oceanospirillales 135619|Oceanospirillales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_15757_5 1278309.KB907104_gene964 1.63e-134 384.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1XI72@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k141_15757_6 1278309.KB907104_gene963 3.25e-245 679.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XIHN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k141_15757_7 1278309.KB907104_gene961 4.55e-107 323.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XI27@135619|Oceanospirillales 135619|Oceanospirillales G phosphomannomutase algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_12977_1 1288826.MSNKSG1_09873 3.59e-82 247.0 COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,1S6MS@1236|Gammaproteobacteria,46AW4@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_12977_2 1288826.MSNKSG1_09878 1.08e-247 678.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RZH1@1236|Gammaproteobacteria,46A21@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k141_12977_4 1288826.MSNKSG1_09888 3.99e-154 436.0 COG0596@1|root,COG0657@1|root,COG0596@2|Bacteria,COG0657@2|Bacteria,1RGAP@1224|Proteobacteria,1S1M7@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 k141_416_1 1335757.SPICUR_09010 4.03e-93 286.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WX1C@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 k141_416_2 472759.Nhal_0092 1.19e-56 196.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_17841_1 1123360.thalar_03006 8.99e-77 251.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT k141_7361_1 104623.Ser39006_01679 1.35e-54 181.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,3ZZTY@613|Serratia 1236|Gammaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_7361_2 349124.Hhal_1697 1.37e-38 132.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Preprotein translocase yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_1119_1 1288826.MSNKSG1_05196 6.15e-211 584.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S2ZF@1236|Gammaproteobacteria,467GM@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_5281_1 388399.SSE37_04015 1.7e-116 348.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter gguA - 3.6.3.17 ko:K10548 ko02010,map02010 M00216 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.5 - - ABC_tran k141_9404_1 998674.ATTE01000001_gene2524 9.35e-196 555.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,45ZTA@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_10144_1 1288826.MSNKSG1_04626 8.48e-240 659.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the class I fructose-bisphosphate aldolase family alf1 - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic k141_10144_2 1288826.MSNKSG1_04621 3.84e-218 603.0 COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria,1SIPM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - - - - - - - - - - - Lactamase_B_3 k141_10144_3 1288826.MSNKSG1_04616 1.25e-85 259.0 COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,4649D@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs dusC GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - ko:K05541 - - - - ko00000,ko01000,ko03016 - - - Dus k141_13649_1 1173026.Glo7428_0631 4.23e-11 64.7 COG1879@1|root,COG1879@2|Bacteria,1G06J@1117|Cyanobacteria 1117|Cyanobacteria G PFAM periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 k141_13649_2 1232683.ADIMK_3124 8.45e-179 530.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain virA - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_7,Response_reg k141_19267_1 1485545.JQLW01000007_gene796 1.01e-20 89.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase type 11 arsM - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 k141_19267_2 1249627.D779_2418 9.44e-65 203.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1RSM2@1236|Gammaproteobacteria,1WX5K@135613|Chromatiales 135613|Chromatiales L Belongs to the Nudix hydrolase family - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_12978_1 887062.HGR_08094 6.92e-40 146.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,4A9VA@80864|Comamonadaceae 28216|Betaproteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_12279_1 1232683.ADIMK_1426 1.06e-116 358.0 COG0404@1|root,COG3665@1|root,COG0404@2|Bacteria,COG3665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C k141_2474_1 90814.KL370891_gene1396 4.31e-06 48.9 COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Type I site-specific restriction-modification system R (restriction) subunit and related helicases - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoEI_R_C,HSDR_N,Helicase_C,ResIII k141_2474_3 889378.Spiaf_2693 1.41e-16 82.4 COG3634@1|root,COG3634@2|Bacteria,2JBED@203691|Spirochaetes 203691|Spirochaetes O Thioredoxin domain - - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k141_4600_1 425104.Ssed_3188 6.15e-214 601.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1R53C@1224|Proteobacteria,1RZQD@1236|Gammaproteobacteria,2QBJ7@267890|Shewanellaceae 1236|Gammaproteobacteria T HDOD domain - GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - - - - - - - - - - HD k141_3872_1 314232.SKA53_01946 1.27e-50 173.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2P8GF@245186|Loktanella 28211|Alphaproteobacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_1136_1 314278.NB231_00740 1.11e-128 383.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1WXRD@135613|Chromatiales 135613|Chromatiales O NfeD-like C-terminal, partner-binding - - - ko:K07403 - - - - ko00000 - - - NfeD k141_9418_1 110662.Syncc9605_1278 2.51e-17 82.0 COG4106@1|root,COG4106@2|Bacteria,1GHFH@1117|Cyanobacteria,1H0IV@1129|Synechococcus 1117|Cyanobacteria S COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_21356_1 1049564.TevJSym_bi00160 3.82e-51 174.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM FIST C domain - - - - - - - - - - - - FIST,FIST_C k141_10903_1 323261.Noc_0510 1.02e-70 227.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales 135613|Chromatiales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH k141_6638_1 1278309.KB907099_gene2939 0.0 1236.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,1XH4K@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the CobB CobQ family pta - 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,DRTGG,PTA_PTB k141_6638_2 1278309.KB907099_gene2938 5.56e-176 496.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XIJK@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 k141_6638_3 331869.BAL199_03199 2.71e-26 109.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,4BPQJ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L PFAM FAD binding domain of DNA photolyase phrB GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_432_1 1260251.SPISAL_02930 9.24e-19 80.9 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1WYM1@135613|Chromatiales 135613|Chromatiales U TIGRFAM preprotein translocase, YajC subunit - - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_432_2 1232683.ADIMK_1050 1.7e-136 395.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,464DG@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_13676_1 1288826.MSNKSG1_01483 3.66e-33 123.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,46759@72275|Alteromonadaceae 1236|Gammaproteobacteria CE COG0473 Isocitrate isopropylmalate dehydrogenase yeaU GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0006082,GO:0006108,GO:0008150,GO:0008152,GO:0009027,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_1288 Iso_dh k141_13676_2 1288826.MSNKSG1_01488 6.02e-179 499.0 COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,466J8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2200 FOG EAL domain ycgF - - ko:K21973 - - - - ko00000 - - - EAL k141_20010_2 1288826.MSNKSG1_09058 0.0 1520.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_8858_1 998674.ATTE01000001_gene2015 1.8e-68 231.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,46039@72273|Thiotrichales 72273|Thiotrichales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) - - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_16555_1 1288826.MSNKSG1_03727 0.0 1209.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,4657J@72275|Alteromonadaceae 1236|Gammaproteobacteria CM COG1042 Acyl-CoA synthetase (NDP forming) yfiQ GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_16555_2 1288826.MSNKSG1_03722 1.97e-227 625.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,464TQ@72275|Alteromonadaceae 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl k141_16555_3 1288826.MSNKSG1_03717 1.4e-204 566.0 COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,465UM@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the ompA family motY - - ko:K21218 ko02040,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_16555_4 1288826.MSNKSG1_03712 3.09e-244 671.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,4642S@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_2002,iYL1228.KPN_01074 Amidohydro_1 k141_16555_5 1288826.MSNKSG1_03707 2.52e-160 448.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,465BF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T k141_16555_6 1288826.MSNKSG1_03700 0.0 1294.0 COG1028@1|root,COG3320@1|root,COG1028@2|Bacteria,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,465Q8@72275|Alteromonadaceae 1236|Gammaproteobacteria M dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - - - - - - - - - - NAD_binding_4,adh_short k141_16555_7 1288826.MSNKSG1_03695 1.65e-61 190.0 297WX@1|root,2ZV3D@2|Bacteria,1PA9M@1224|Proteobacteria,1STMQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_16555_8 1288826.MSNKSG1_03690 0.0 1682.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,4641E@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase M16 family ptrA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_1952_1 1247963.JPHU01000029_gene93 6.84e-116 340.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve,rve_3 k141_6097_2 375451.RD1_0292 4.39e-37 126.0 COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,2P3I9@2433|Roseobacter 28211|Alphaproteobacteria G Domain of unknown function (DUF4170) MA20_05805 - - - - - - - - - - - DUF4170 k141_22164_1 1123393.KB891333_gene2529 1.93e-20 84.3 2A022@1|root,30N4D@2|Bacteria,1PU9H@1224|Proteobacteria,2WARI@28216|Betaproteobacteria,1KRVX@119069|Hydrogenophilales 119069|Hydrogenophilales S Domain of unknown function (DUF1840) - - - - - - - - - - - - DUF1840 k141_18033_2 1288826.MSNKSG1_06158 7.74e-207 574.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,465NP@72275|Alteromonadaceae 1236|Gammaproteobacteria C electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha k141_18033_3 1288826.MSNKSG1_06163 5.99e-163 457.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,464UJ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Electron transfer flavoprotein etfB - - ko:K03521 - - - - ko00000 - - - ETF k141_18033_4 1288826.MSNKSG1_06168 0.0 1127.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,464BX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Electron transfer flavoprotein-ubiquinone oxidoreductase etfD - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8,Thi4 k141_18033_5 1288826.MSNKSG1_06173 4.52e-104 301.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,467AX@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k141_18033_6 1288826.MSNKSG1_06178 2.67e-134 380.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,1S9CC@1236|Gammaproteobacteria,467ZR@72275|Alteromonadaceae 1236|Gammaproteobacteria T protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 k141_18033_7 1288826.MSNKSG1_06183 1.31e-211 585.0 COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,1RXYN@1236|Gammaproteobacteria,4688B@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxygen-independent coproporphyrinogen III oxidase - - - - - - - - - - - - Radical_SAM k141_18033_8 1288826.MSNKSG1_06188 3.29e-31 112.0 COG2062@1|root,COG2062@2|Bacteria,1NH0V@1224|Proteobacteria,1SJ8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T phosphohistidine phosphatase, SixA - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 k141_8275_1 1499967.BAYZ01000019_gene6314 1.03e-13 69.7 COG2062@1|root,COG2062@2|Bacteria,2NRKX@2323|unclassified Bacteria 2|Bacteria T Histidine phosphatase superfamily (branch 1) sixA - 3.6.1.55 ko:K03574,ko:K08296 - - - - ko00000,ko01000,ko03400 - - - His_Phos_1 k141_8275_2 1137799.GZ78_07160 3.93e-50 160.0 COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,1SA3S@1236|Gammaproteobacteria,1XQMF@135619|Oceanospirillales 135619|Oceanospirillales C Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_8295_1 1278309.KB907099_gene2748 2.17e-12 65.5 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XHRF@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter, ATP-binding protein - - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_8295_2 1278309.KB907099_gene2747 1.03e-227 632.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1XH3N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K11961 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_21512_1 555778.Hneap_1970 3.71e-71 234.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_17286_1 1500893.JQNB01000001_gene1797 1.97e-31 113.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1X5XV@135614|Xanthomonadales 135614|Xanthomonadales J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase k141_17286_2 1500890.JQNL01000001_gene2939 3.75e-50 161.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1X6H0@135614|Xanthomonadales 135614|Xanthomonadales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS k141_19406_1 90814.KL370891_gene622 8.84e-45 166.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,461PB@72273|Thiotrichales 72273|Thiotrichales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_9 k141_3387_1 1288826.MSNKSG1_08123 8.01e-93 280.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,464K3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rsmC - 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS,MTS_N k141_3387_2 1288826.MSNKSG1_08118 7.73e-144 406.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,466QA@72275|Alteromonadaceae 1236|Gammaproteobacteria H riboflavin synthase, alpha ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c19160,iECP_1309.ECP_1609,ic_1306.c2056 Lum_binding k141_16582_1 439497.RR11_1351 2.69e-49 167.0 COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,4NAZR@97050|Ruegeria 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 k141_16582_2 52598.EE36_10994 1.11e-41 149.0 COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria,3ZUWM@60136|Sulfitobacter 28211|Alphaproteobacteria S ATPases associated with a variety of cellular activities MA20_34815 - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran k141_11061_1 1042375.AFPL01000013_gene2462 1.12e-96 288.0 COG2141@1|root,COG2141@2|Bacteria,1MWI8@1224|Proteobacteria,1S10Y@1236|Gammaproteobacteria,468VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase k141_11061_2 1042375.AFPL01000013_gene2461 2.88e-127 365.0 COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,1S2WU@1236|Gammaproteobacteria,46836@72275|Alteromonadaceae 1236|Gammaproteobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored k141_11061_3 1042375.AFPL01000013_gene2460 8.19e-138 395.0 COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,1S12T@1236|Gammaproteobacteria,467JE@72275|Alteromonadaceae 1236|Gammaproteobacteria S F420-0:Gamma-glutamyl ligase - - 6.3.2.31,6.3.2.34 ko:K12234 ko00680,ko01120,map00680,map01120 M00378 R09399,R09400 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000 - - - F420_ligase k141_11061_4 1042375.AFPL01000013_gene2459 1.12e-68 215.0 COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,1SDYT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Guanylyl transferase CofC like - - 2.7.7.68 ko:K14941 ko00680,ko01120,map00680,map01120 M00378 R09397 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CofC k141_11061_5 1042375.AFPL01000013_gene2458 1.15e-153 441.0 COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,1RZ77@1236|Gammaproteobacteria,467KY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterised protein family UPF0052 - - 2.7.8.28 ko:K11212 ko00680,ko01120,map00680,map01120 M00378 R09398 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - UPF0052 k141_11061_6 1042375.AFPL01000013_gene2457 3.63e-231 644.0 COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,1RSCG@1236|Gammaproteobacteria,4668T@72275|Alteromonadaceae 1236|Gammaproteobacteria H Elongator protein 3, MiaB family, Radical SAM - - 2.5.1.77 ko:K11779 ko00680,ko01120,map00680,map01120 M00378 R09396 RC01381,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - CofC,Radical_SAM k141_11061_7 1042375.AFPL01000013_gene2456 1.95e-111 325.0 COG1309@1|root,COG1309@2|Bacteria,1ND64@1224|Proteobacteria,1RS7A@1236|Gammaproteobacteria,466YJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K YcdC-like protein, C-terminal region - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_3,TetR_N k141_11061_8 1278309.KB907100_gene2148 2.11e-165 463.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1XH39@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k141_11061_9 207954.MED92_06588 2.67e-114 332.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1XHYB@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG k141_6123_1 1101195.Meth11DRAFT_0731 4.29e-19 85.9 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,2KKJ0@206350|Nitrosomonadales 206350|Nitrosomonadales F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_6123_2 519989.ECTPHS_03919 2.24e-104 311.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1WWU0@135613|Chromatiales 135613|Chromatiales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_18708_1 203122.Sde_3378 2.49e-69 216.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,464II@72275|Alteromonadaceae 1236|Gammaproteobacteria F Deoxynucleoside kinase dgk - - - - - - - - - - - dNK k141_18708_2 1028803.GG9_0206 9.69e-50 164.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1Y8PP@135625|Pasteurellales 135625|Pasteurellales H Protein involved in 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity and folic acid-containing compound biosynthetic process folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_15942_1 391624.OIHEL45_07300 3.79e-111 332.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Pyridine nucleotide-disulphide oxidoreductase thcD - 1.14.13.111,1.18.1.3 ko:K00529,ko:K16968 ko00071,ko00360,ko00920,ko01120,ko01220,map00071,map00360,map00920,map01120,map01220 M00545 R02000,R06782,R06783,R09513 RC00098,RC02556 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C k141_10334_1 376733.IT41_00350 4.53e-125 365.0 COG1638@1|root,COG1638@2|Bacteria,1NU34@1224|Proteobacteria,2VFZE@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP k141_18059_1 1288826.MSNKSG1_04636 1.51e-39 134.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,467AH@72275|Alteromonadaceae 1236|Gammaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18 k141_18059_2 1288826.MSNKSG1_04641 2.37e-217 599.0 COG3687@1|root,COG3687@2|Bacteria,1RBP4@1224|Proteobacteria,1RZJF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metal-dependent hydrolase - - - ko:K07044 - - - - ko00000 - - - Metal_hydrol k141_18059_3 1288826.MSNKSG1_04646 1.11e-144 410.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,466RY@72275|Alteromonadaceae 1236|Gammaproteobacteria S VIT family - - - - - - - - - - - - VIT1 k141_18059_4 1288826.MSNKSG1_04651 1.46e-146 424.0 COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,1RNU6@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0348 Polyferredoxin - - - - - - - - - - - - Fer4_5 k141_1308_1 744985.HIMB59_00005190 6.81e-06 48.5 COG0715@1|root,COG0715@2|Bacteria,1R4AB@1224|Proteobacteria,2U2A0@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 k141_1308_2 398580.Dshi_2539 7.84e-40 139.0 COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2U67X@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional - - - - - - - - - - - - FCD,GntR k141_576_1 1288826.MSNKSG1_18065 1.51e-77 240.0 COG3203@1|root,COG3203@2|Bacteria,1N04Q@1224|Proteobacteria 1224|Proteobacteria M PFAM porin Gram-negative type - - - ko:K08720,ko:K09476 ko01501,ko02020,ko05111,map01501,map02020,map05111 M00746 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.1.1.1,1.B.1.2.1 - - Porin_4 k141_576_3 1288826.MSNKSG1_18070 8.17e-11 61.2 COG3025@1|root,COG3025@2|Bacteria,1MY43@1224|Proteobacteria,1RMP4@1236|Gammaproteobacteria,463Y2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Adenylate cyclase ygiF - 3.6.1.25 ko:K18446 - - - - ko00000,ko01000 - - - CHAD,CYTH k141_8296_1 396588.Tgr7_2206 2.3e-112 336.0 COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,1RMGI@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes lplA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_4078,iE2348C_1286.E2348C_4684,iECDH10B_1368.ECDH10B_4544,iECDH1ME8569_1439.ECDH1ME8569_4242,iEcDH1_1363.EcDH1_3612,iJO1366.b4386,iSDY_1059.SDY_4647,iY75_1357.Y75_RS22890 BPL_LplA_LipB,Lip_prot_lig_C k141_2641_1 713586.KB900536_gene998 5.63e-78 239.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1WWCR@135613|Chromatiales 135613|Chromatiales K response regulator receiver - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_10335_1 1185766.DL1_03665 4.38e-88 273.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2XMB6@285107|Thioclava 28211|Alphaproteobacteria C Catalyzes the formation of succinate from succinate semialdehyde gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_15943_1 1026882.MAMP_00731 1.39e-34 132.0 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,460MD@72273|Thiotrichales 72273|Thiotrichales T HDOD domain - - - - - - - - - - - - EAL,HDOD k141_11062_1 1121904.ARBP01000007_gene3050 2.93e-41 148.0 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_11062_2 452471.Aasi_0028 2.09e-06 52.4 COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,47MQP@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - k141_9568_1 314345.SPV1_13172 6.15e-49 169.0 COG3408@1|root,COG3408@2|Bacteria,1PGVT@1224|Proteobacteria 1224|Proteobacteria G Alkaline and neutral invertase - - - - - - - - - - - - GDE_C,Glyco_hydro_100 k141_9568_2 879212.DespoDRAFT_02680 2.83e-10 60.5 COG0561@1|root,COG0561@2|Bacteria,1QFFG@1224|Proteobacteria,42R6U@68525|delta/epsilon subdivisions,2WN0Q@28221|Deltaproteobacteria,2MMQ9@213118|Desulfobacterales 28221|Deltaproteobacteria S HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP k141_14442_1 1288826.MSNKSG1_06548 1.28e-08 54.7 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,4651F@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG0583 Transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k141_14442_2 1288826.MSNKSG1_06543 0.0 945.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,4642D@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k141_14442_3 1288826.MSNKSG1_06538 9.15e-157 439.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,464MP@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C k141_19407_1 1196835.A458_18720 3.49e-20 90.1 COG0668@1|root,COG0668@2|Bacteria,1RCM8@1224|Proteobacteria,1SCM2@1236|Gammaproteobacteria,1YZTR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel - - - - - - - - - - - - MS_channel k141_8875_1 765912.Thimo_0562 3.26e-75 232.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1WXHM@135613|Chromatiales 135613|Chromatiales IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 k141_8875_2 1121921.KB898706_gene2854 2.54e-49 163.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,2PNQ3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_6124_1 1209072.ALBT01000033_gene1729 1.54e-83 268.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1FGTG@10|Cellvibrio 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_17287_1 1283300.ATXB01000001_gene744 1.72e-117 365.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XDWG@135618|Methylococcales 135618|Methylococcales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_1309_1 1454004.AW11_01596 9.28e-13 67.8 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,1KQGC@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k141_1309_2 1120983.KB894572_gene2997 4.9e-34 121.0 2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_20750_2 1288826.MSNKSG1_01858 4.09e-60 206.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,465CI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria vgrG GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564 - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_2642_1 511062.GU3_05405 4.99e-59 201.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1Y3JF@135624|Aeromonadales 135624|Aeromonadales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C k141_21514_1 1288826.MSNKSG1_10818 1.14e-128 370.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,464BE@72275|Alteromonadaceae 1236|Gammaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_4790_1 909663.KI867150_gene1371 3.81e-34 135.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k141_10336_1 391625.PPSIR1_00715 2.96e-17 90.1 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k141_8876_1 580332.Slit_1176 1.11e-57 202.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria 28216|Betaproteobacteria S alpha-2-macroglobulin domain protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl k141_8298_1 644076.SCH4B_2809 1.09e-56 197.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,4NAGS@97050|Ruegeria 28211|Alphaproteobacteria M penicillin-binding protein mrcB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_15944_1 1255043.TVNIR_3207 2.82e-49 163.0 2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,1SJ45@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_12490_2 1499502.EV12_0967 4.64e-22 89.7 COG4095@1|root,COG4095@2|Bacteria,1G9AI@1117|Cyanobacteria,1MMQF@1212|Prochloraceae 1117|Cyanobacteria S PQ loop repeat - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - MtN3_slv,PQ-loop k141_18710_1 713586.KB900536_gene1349 1.06e-58 189.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1WW8G@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA k141_18710_2 1122197.ATWI01000013_gene2241 1.28e-10 61.6 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,464PF@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_13162_1 1288826.MSNKSG1_05361 3.99e-106 311.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RQVA@1236|Gammaproteobacteria,467B7@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_13162_2 1288826.MSNKSG1_05356 4.14e-206 572.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,1S5E8@1236|Gammaproteobacteria,46BX6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_13162_3 1288826.MSNKSG1_05351 3.82e-123 353.0 COG3218@1|root,COG3218@2|Bacteria,1RED4@1224|Proteobacteria 1224|Proteobacteria S transport system auxiliary component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux k141_11879_1 1278309.KB907105_gene1545 8.57e-124 362.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XIK3@135619|Oceanospirillales 135619|Oceanospirillales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k141_14669_1 1569209.BBPH01000022_gene337 2.54e-17 80.9 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2PVMU@265|Paracoccus 28211|Alphaproteobacteria H Cobalamin biosynthesis protein CobT VWA domain cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C k141_14669_2 83219.PM02_01740 4.52e-61 204.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,3ZV3M@60136|Sulfitobacter 28211|Alphaproteobacteria E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C k141_6290_1 1266909.AUAG01000010_gene2627 8.48e-88 270.0 COG0547@1|root,COG0547@2|Bacteria,1QDR6@1224|Proteobacteria,1T9UH@1236|Gammaproteobacteria,1WW56@135613|Chromatiales 135613|Chromatiales E PFAM Glycosyl transferase, family - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_7697_1 745310.G432_08130 1.08e-05 46.6 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria,2K0RD@204457|Sphingomonadales 204457|Sphingomonadales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 k141_7697_2 252305.OB2597_07959 1.6e-53 169.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2UBQ1@28211|Alphaproteobacteria,2PEE2@252301|Oceanicola 28211|Alphaproteobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 k141_7697_3 1288298.rosmuc_02342 1.18e-41 143.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2TTKD@28211|Alphaproteobacteria,46NSZ@74030|Roseovarius 28211|Alphaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_20937_1 1288826.MSNKSG1_02223 1.15e-126 368.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPGB@1236|Gammaproteobacteria,464X4@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases hcaD - 1.3.8.7,1.3.8.8 ko:K00249,ko:K00255 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_15361_1 351348.Maqu_3370 1.2e-63 197.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,466RT@72275|Alteromonadaceae 1236|Gammaproteobacteria O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB k141_15361_2 1288826.MSNKSG1_11818 1.21e-97 295.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1S1HS@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - DUF1298,WES_acyltransf k141_8391_1 1122135.KB893157_gene245 1.09e-140 403.0 COG0583@1|root,COG0583@2|Bacteria,1MU3N@1224|Proteobacteria,2TTS9@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_9779_1 675817.VDA_001963 1.27e-10 62.8 COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,1Y2PS@135623|Vibrionales 135623|Vibrionales V Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_D23 k141_9779_2 768066.HELO_1756 6.85e-13 67.0 COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1S26B@1236|Gammaproteobacteria,1XM78@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator slyA - - ko:K06075 - - - - ko00000,ko03000 - - - MarR,MarR_2 k141_16049_1 207954.MED92_02636 3.44e-87 268.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XHQ6@135619|Oceanospirillales 135619|Oceanospirillales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069,ko:K11073 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 k141_16049_2 1278309.KB907099_gene2973 9e-227 638.0 COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,1RPY9@1236|Gammaproteobacteria,1XI6Z@135619|Oceanospirillales 135619|Oceanospirillales T diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 k141_18141_1 1288826.MSNKSG1_09133 6.42e-163 465.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,4643J@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k141_730_1 1288826.MSNKSG1_17950 1.09e-311 856.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,46485@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB mshE - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N k141_9780_1 1294273.roselon_00665 3.85e-49 159.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS k141_11184_1 1288826.MSNKSG1_10243 5.99e-103 297.0 28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,1S270@1236|Gammaproteobacteria,4673R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Nucleoside 2-deoxyribosyltransferase YtoQ - - - - - - - - - - - - Nuc_deoxyri_tr3 k141_11184_2 1288826.MSNKSG1_10238 2.99e-65 214.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,468GC@72275|Alteromonadaceae 1236|Gammaproteobacteria CH FAD binding domain - - 1.14.13.7 ko:K03380 ko00623,ko00627,ko01120,map00623,map00627,map01120 - R00815,R03566 RC00046,RC00236 ko00000,ko00001,ko01000 - - - FAD_binding_3,Phe_hydrox_dim k141_20243_1 631362.Thi970DRAFT_04877 2.52e-93 286.0 COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1WXQU@135613|Chromatiales 135613|Chromatiales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_13274_1 1278309.KB907101_gene516 2.19e-39 135.0 2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,1SATY@1236|Gammaproteobacteria,1XM06@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_13274_2 1278309.KB907101_gene517 4.76e-98 300.0 COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,1SZTB@1236|Gammaproteobacteria,1XRNY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_17441_1 545243.BAEV01000189_gene2582 6.33e-19 89.0 COG5433@1|root,COG5433@2|Bacteria,1UZWV@1239|Firmicutes,24DPT@186801|Clostridia,36UF1@31979|Clostridiaceae 186801|Clostridia L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_assoc k141_20_1 1385515.N791_13720 5.06e-45 159.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S2K0@1236|Gammaproteobacteria,1X321@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_15363_1 317025.Tcr_0169 1.62e-68 224.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales 72273|Thiotrichales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_18849_1 572477.Alvin_0475 5.17e-22 95.9 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales 135613|Chromatiales G pfam mofrl - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL k141_18849_2 395493.BegalDRAFT_0683 4.45e-44 157.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,460G5@72273|Thiotrichales 72273|Thiotrichales T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 k141_2807_2 1283300.ATXB01000001_gene900 4.43e-49 160.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1XH0F@135618|Methylococcales 135618|Methylococcales NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_16050_1 96561.Dole_3250 5.57e-54 182.0 COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales 28221|Deltaproteobacteria L PFAM transposase IS4 family protein - - - - - - - - - - - - DDE_Tnp_1,DUF772 k141_1416_1 1278309.KB907108_gene1623 3.54e-165 471.0 COG2984@1|root,COG2984@2|Bacteria,1PHTD@1224|Proteobacteria,1RRJH@1236|Gammaproteobacteria,1XMRN@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind k141_1416_2 1278309.KB907108_gene1622 5.25e-203 591.0 COG4564@1|root,COG5002@1|root,COG4564@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1XRZS@135619|Oceanospirillales 135619|Oceanospirillales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Response_reg k141_13275_1 1278309.KB907109_gene3284 5.32e-177 498.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XHRU@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_18850_1 1453501.JELR01000001_gene1931 1.15e-11 65.9 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,464WE@72275|Alteromonadaceae 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 k141_18850_2 1049564.TevJSym_ba00240 1.41e-44 147.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity gloA - - ko:K08234 - - - - ko00000 - - - Glyoxalase k141_732_1 89187.ISM_11065 2.48e-139 409.0 COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VFZH@28211|Alphaproteobacteria,46PQ0@74030|Roseovarius 28211|Alphaproteobacteria H Catalyzes the synthesis of activated sulfate cysC - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,HTH_24,PUA_2 k141_20938_1 713586.KB900536_gene2790 6.98e-76 230.0 COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,1S7XG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - - - - - - - - - - TetR_C_10,TetR_N k141_20938_2 713586.KB900536_gene2789 1.45e-86 255.0 COG2210@1|root,COG2210@2|Bacteria,1RFWY@1224|Proteobacteria,1SQ8R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE k141_20938_3 292415.Tbd_1982 6.82e-28 102.0 COG0425@1|root,COG0425@2|Bacteria,1PZNF@1224|Proteobacteria,2W43C@28216|Betaproteobacteria 28216|Betaproteobacteria O Sulfurtransferase TusA - - - - - - - - - - - - TusA k141_20938_4 1049564.TevJSym_ac01960 8.63e-58 184.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid k141_8392_2 1288826.MSNKSG1_16581 2.4e-166 465.0 COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,1RNBZ@1236|Gammaproteobacteria,4652H@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH k141_8392_3 1288826.MSNKSG1_16576 6.9e-48 163.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_14670_1 247634.GPB2148_286 1.1e-31 125.0 2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,1RSN5@1236|Gammaproteobacteria,1J91N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_14670_2 1249627.D779_0636 3.98e-20 100.0 COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1WXF8@135613|Chromatiales 135613|Chromatiales T PFAM Chemotaxis methyl-accepting receptor, signalling - - - - - - - - - - - - HAMP,MCPsignal,sCache_2 k141_12572_1 1288826.MSNKSG1_02599 3.98e-228 650.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,465DP@72275|Alteromonadaceae 1236|Gammaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042 DUF3458,DUF3458_C,Peptidase_M1 k141_12572_2 1288826.MSNKSG1_02594 1.03e-203 563.0 2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,46438@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2797) LA2027 - - - - - - - - - - - DUF2797 k141_12572_3 1288826.MSNKSG1_02589 1.27e-63 194.0 COG3139@1|root,COG3139@2|Bacteria,1N7ZT@1224|Proteobacteria,1SC7K@1236|Gammaproteobacteria,468IW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1315) - - - ko:K09916 - - - - ko00000 - - - DUF1315 k141_12572_4 1288826.MSNKSG1_02584 2.36e-196 545.0 COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,463ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) glpG GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02441 - - - - ko00000 - - - NRho,Rhomboid,Rhomboid_N k141_12572_5 1288826.MSNKSG1_02579 3.12e-250 686.0 COG0639@1|root,COG0639@2|Bacteria,1QE1Y@1224|Proteobacteria,1RRG9@1236|Gammaproteobacteria,4646C@72275|Alteromonadaceae 1236|Gammaproteobacteria T Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - - - - - - - - - - Metallophos k141_12572_6 1288826.MSNKSG1_02574 4.07e-213 588.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,464AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iEcSMS35_1347.EcSMS35_2767 NAD_kinase k141_12572_7 1288826.MSNKSG1_02569 5.2e-180 508.0 COG4372@1|root,COG4372@2|Bacteria,1MX74@1224|Proteobacteria,1RMWF@1236|Gammaproteobacteria,466QI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transposase - - - - - - - - - - - - - k141_2808_1 1266909.AUAG01000022_gene1682 1.3e-81 262.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_13276_1 265072.Mfla_0519 6.03e-23 96.3 COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,2KNEN@206350|Nitrosomonadales 206350|Nitrosomonadales S Cobalt uptake substrate-specific transmembrane region - - - - - - - - - - - - CbiM k141_16770_1 1278309.KB907105_gene1419 8.41e-215 616.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales 135619|Oceanospirillales S of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL k141_16770_2 399739.Pmen_3260 3.57e-06 55.8 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1YF68@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Universal stress protein family ydaA - - ko:K14055 - - - - ko00000 - - - Usp k141_16770_3 1278309.KB907105_gene1421 5.4e-166 479.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1XHAP@135619|Oceanospirillales 135619|Oceanospirillales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k141_744_2 314278.NB231_09368 2.91e-94 292.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) cyaB - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,MASE2 k141_20968_1 1278309.KB907106_gene1358 9.76e-291 803.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1XH8T@135619|Oceanospirillales 135619|Oceanospirillales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k141_20968_2 1278309.KB907106_gene1357 5.59e-38 128.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1XKYP@135619|Oceanospirillales 135619|Oceanospirillales J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p k141_5621_1 395493.BegalDRAFT_0118 9.06e-19 87.8 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,461PA@72273|Thiotrichales 72273|Thiotrichales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_5621_2 1089551.KE386572_gene453 2.84e-20 87.8 COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9AJ@28211|Alphaproteobacteria,4BTCA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_5621_3 983920.Y88_1793 5.62e-34 138.0 COG5001@1|root,COG5001@2|Bacteria,1R04C@1224|Proteobacteria,2TYKH@28211|Alphaproteobacteria 28211|Alphaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_3 k141_5621_4 998088.B565_3083 1.26e-06 51.6 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y57Z@135624|Aeromonadales 135624|Aeromonadales NT Cache domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k141_15385_1 1278309.KB907099_gene3086 5.52e-151 444.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XHD0@135619|Oceanospirillales 135619|Oceanospirillales T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_2,sCache_2 k141_15385_2 1278309.KB907099_gene3087 0.0 876.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,1XHEJ@135619|Oceanospirillales 135619|Oceanospirillales C malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_15385_3 1123355.JHYO01000003_gene2802 1.11e-06 50.1 COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VFYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_15385_4 1278309.KB907099_gene3090 3e-34 123.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,1XMGP@135619|Oceanospirillales 135619|Oceanospirillales S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg k141_3520_1 296587.XP_002504675.1 2.55e-36 134.0 COG2230@1|root,2QQW3@2759|Eukaryota,37PQP@33090|Viridiplantae,34GV7@3041|Chlorophyta 3041|Chlorophyta M Mycolic acid cyclopropane synthetase - - - - - - - - - - - - CMAS k141_3520_2 543913.D521_1831 2.29e-27 108.0 2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,2VVUJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 k141_3520_3 666681.M301_1471 8.35e-86 263.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2VQHY@28216|Betaproteobacteria,2KKZM@206350|Nitrosomonadales 206350|Nitrosomonadales S Phospholipid methyltransferase - - - - - - - - - - - - DUF1295 k141_3520_5 1286106.MPL1_07443 1.62e-77 236.0 COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer Membrane Lipoprotein blc4 - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k141_9800_1 1123248.KB893315_gene3164 8.39e-69 219.0 COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1INU1@117747|Sphingobacteriia 976|Bacteroidetes O Pyridine nucleotide-disulphide oxidoreductase ypdA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 k141_6298_1 1278309.KB907099_gene2464 1.77e-113 335.0 COG1577@1|root,COG1577@2|Bacteria,1RIKN@1224|Proteobacteria,1S678@1236|Gammaproteobacteria,1XJSX@135619|Oceanospirillales 135619|Oceanospirillales I GHMP kinases N terminal domain - - - - - - - - - - - - GHMP_kinases_C,GHMP_kinases_N k141_6298_2 1278309.KB907099_gene2463 3.32e-264 725.0 COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria,1XHVV@135619|Oceanospirillales 135619|Oceanospirillales I Hydroxymethylglutaryl-coenzyme A synthase N terminal - - - - - - - - - - - - HMG_CoA_synt_C,HMG_CoA_synt_N k141_6298_3 1278309.KB907099_gene2462 2.29e-159 452.0 COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,1RP1W@1236|Gammaproteobacteria,1XJ1Z@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - - - - - - - - - - - FMN_dh k141_17450_1 1288826.MSNKSG1_05071 3.84e-78 236.0 COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1RSIE@1236|Gammaproteobacteria,46AD9@72275|Alteromonadaceae 1236|Gammaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD_2 k141_17450_2 1288826.MSNKSG1_05076 2.04e-183 511.0 COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,4676N@72275|Alteromonadaceae 1236|Gammaproteobacteria C Fe-S protein ycbX GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - ko:K07140 - - - - ko00000 - - - FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1 k141_17450_3 1288826.MSNKSG1_05081 7.05e-176 506.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,463XW@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains uup GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_12599_1 1278309.KB907112_gene3342 2.3e-164 462.0 COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,1XHEX@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator pdhR - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR k141_12599_2 1278309.KB907112_gene3341 1.1e-235 650.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RRF1@1236|Gammaproteobacteria,1XIBF@135619|Oceanospirillales 135619|Oceanospirillales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_12599_3 1278309.KB907112_gene3340 1.07e-97 286.0 COG4665@1|root,COG4665@2|Bacteria,1R4Q7@1224|Proteobacteria,1S3JY@1236|Gammaproteobacteria,1XJD6@135619|Oceanospirillales 135619|Oceanospirillales Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_18865_1 1288826.MSNKSG1_01133 3.42e-160 461.0 COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,1RMF5@1236|Gammaproteobacteria,46743@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase rstB - 2.7.13.3 ko:K02484,ko:K07639 ko02020,map02020 M00446 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_18865_2 1288826.MSNKSG1_01138 0.0 993.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,464DH@72275|Alteromonadaceae 1236|Gammaproteobacteria C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_18865_3 1288826.MSNKSG1_01143 3.71e-259 710.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,464Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k141_18865_4 1288826.MSNKSG1_01148 4.26e-220 607.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,465TZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.6,2.1.3.9 ko:K00611,ko:K09065,ko:K13252 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_18865_5 1288826.MSNKSG1_01153 1.63e-71 215.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,466TX@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin k141_18865_6 1288826.MSNKSG1_01158 3.82e-77 237.0 COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,1T2GY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tolA - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_2,TonB_C k141_13978_1 1278309.KB907101_gene349 8.79e-187 522.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XIDD@135619|Oceanospirillales 135619|Oceanospirillales S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k141_13978_2 1278309.KB907101_gene348 1.86e-227 634.0 COG0583@1|root,COG0583@2|Bacteria,1Q531@1224|Proteobacteria,1RWPD@1236|Gammaproteobacteria,1XIWT@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_13978_3 1278309.KB907101_gene347 1.13e-248 682.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1XH3X@135619|Oceanospirillales 135619|Oceanospirillales S PFAM Amidohydrolase 2 - - 4.2.1.83 ko:K10220 ko00362,ko01120,map00362,map01120 - R04478 RC00498 ko00000,ko00001,ko01000 - - - Amidohydro_2 k141_13978_4 1278309.KB907101_gene346 3.31e-139 395.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,1XIWA@135619|Oceanospirillales 135619|Oceanospirillales H Aldolase/RraA - - 4.1.3.17 ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 - R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000 - - - RraA-like k141_13978_5 1278309.KB907101_gene345 1.14e-207 579.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1XHK7@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF k141_8404_1 743720.Psefu_3115 1.91e-282 820.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C indolepyruvate ferredoxin oxidoreductase iorA - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C k141_8404_2 1282876.BAOK01000001_gene3321 2.59e-231 660.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_7853_3 1288826.MSNKSG1_16621 1.63e-57 189.0 COG2199@1|root,COG3706@2|Bacteria 2|Bacteria T GGDEF domain - - 2.7.7.65 ko:K13069 - - R08057 - ko00000,ko01000 - - - CZB,GGDEF,PAS_3,PAS_9 k141_7853_4 1288826.MSNKSG1_16616 1.21e-237 658.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1,dCache_2 k141_12720_1 1278309.KB907099_gene2853 7.53e-151 448.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XIC7@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_12720_2 1278309.KB907099_gene2854 1.69e-179 513.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XIDR@135619|Oceanospirillales 135619|Oceanospirillales C reductase - - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2 k141_5031_1 90814.KL370891_gene1851 5.73e-153 437.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales 72273|Thiotrichales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k141_11362_1 1049564.TevJSym_bw00100 5.42e-56 181.0 2C20N@1|root,32SGJ@2|Bacteria,1N3M9@1224|Proteobacteria,1S9VG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11362_2 768671.ThimaDRAFT_3369 4.6e-31 122.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales 135613|Chromatiales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 k141_13432_1 1168067.JAGP01000001_gene165 2.55e-141 411.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_14120_2 765912.Thimo_0389 2.15e-107 322.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1WWRH@135613|Chromatiales 1236|Gammaproteobacteria G Fructose-bisphosphate aldolase, class II, Calvin cycle subtype - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - Dabb,F_bP_aldolase k141_8538_1 570268.ANBB01000033_gene2212 9.65e-19 95.9 COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4EGXY@85012|Streptosporangiales 201174|Actinobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_15544_1 1342299.Z947_2749 1.72e-21 93.2 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,3ZW5S@60136|Sulfitobacter 28211|Alphaproteobacteria M Bacterial transferase hexapeptide (six repeats) lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k141_15544_2 351016.RAZWK3B_15683 2.43e-61 205.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2P2I5@2433|Roseobacter 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_16898_1 580332.Slit_2469 3.08e-35 137.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VRWJ@28216|Betaproteobacteria,44W8C@713636|Nitrosomonadales 28216|Betaproteobacteria NT histidine kinase HAMP region domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_9898_1 1216007.AOPM01000102_gene746 1.6e-13 77.4 COG2199@1|root,COG2199@2|Bacteria,1RDMU@1224|Proteobacteria,1RY8G@1236|Gammaproteobacteria,2PZZD@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k141_9898_2 379731.PST_0466 1.69e-20 86.7 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1Z184@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186 Pribosyltran k141_5798_1 1267211.KI669560_gene1671 2.53e-05 52.0 COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4NF5X@976|Bacteroidetes 976|Bacteroidetes T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA k141_17607_1 1121939.L861_21940 3.48e-10 57.0 COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,1XMQT@135619|Oceanospirillales 135619|Oceanospirillales O Cbb3-type cytochrome oxidase component FixQ ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_17607_2 522306.CAP2UW1_2533 2.4e-30 116.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1KQ6R@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_19016_2 292415.Tbd_2109 2.75e-22 91.3 2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,2W41I@28216|Betaproteobacteria,1KTCV@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - k141_19016_3 1265313.HRUBRA_02790 2.11e-06 51.6 COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,1RQWI@1236|Gammaproteobacteria,1J5R8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k141_21770_1 160488.PP_2494 8.31e-76 237.0 28HJH@1|root,2Z7UN@2|Bacteria,1R3V2@1224|Proteobacteria,1RNCZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10661_1 1178482.BJB45_02195 7.27e-20 84.3 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XJJA@135619|Oceanospirillales 135619|Oceanospirillales O Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k141_10661_2 105559.Nwat_1094 1.4e-114 345.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales 135613|Chromatiales T SMART Nucleotide binding protein, PINc - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_15558_1 1208321.D104_14800 5.92e-49 159.0 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,1XK0Z@135619|Oceanospirillales 135619|Oceanospirillales G Methylglyoxal synthase mgsA - 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS k141_15558_2 290398.Csal_0934 3.87e-46 164.0 COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1XJKN@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the glucose-6-phosphate 1-epimerase family - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim k141_12034_1 1150621.SMUL_0361 2.34e-73 251.0 COG0834@1|root,COG2199@1|root,COG2203@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria 1224|Proteobacteria T GAF domain - - - - - - - - - - - - GAF,GAF_2,GGDEF,PAS,PAS_4,PAS_9 k141_17608_1 1122137.AQXF01000002_gene283 3.79e-101 301.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria 28211|Alphaproteobacteria L NADP-dependent oxidoreductase - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k141_5799_1 1417296.U879_13905 8.84e-104 313.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Major facilitator Superfamily narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 k141_19017_1 207954.MED92_02354 2.64e-23 97.4 COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,1S90D@1236|Gammaproteobacteria,1XM2U@135619|Oceanospirillales 135619|Oceanospirillales K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE k141_20417_1 398580.Dshi_2581 8.29e-18 82.8 29M59@1|root,3082Q@2|Bacteria,1PUXY@1224|Proteobacteria,2U6M4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k141_20417_2 1185766.DL1_05665 3.77e-52 183.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2XKHP@285107|Thioclava 28211|Alphaproteobacteria L Helicase associated domain (HA2) Add an annotation hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_21154_1 1278309.KB907099_gene2606 7.95e-10 58.2 COG4125@1|root,COG4125@2|Bacteria,1RHF1@1224|Proteobacteria,1SBGV@1236|Gammaproteobacteria,1XS9K@135619|Oceanospirillales 135619|Oceanospirillales S Chlorhexidine efflux transporter - - - - - - - - - - - - BTP k141_21154_2 1278309.KB907099_gene2605 3.47e-81 244.0 2E92J@1|root,333BK@2|Bacteria,1N7V2@1224|Proteobacteria,1SDCF@1236|Gammaproteobacteria,1XPIP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_2251_1 1288826.MSNKSG1_09403 0.0 1018.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,464P4@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_2251_2 1288826.MSNKSG1_09398 0.0 1092.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C k141_2251_3 1288826.MSNKSG1_09393 4.02e-289 791.0 COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,1RZPI@1236|Gammaproteobacteria,46BEA@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2200 FOG EAL domain - - - - - - - - - - - - EAL k141_2251_4 1288826.MSNKSG1_09388 1.09e-120 345.0 COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,467A7@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG3038 Cytochrome B561 yceJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k141_2982_1 1288826.MSNKSG1_17231 1.55e-265 738.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,46466@72275|Alteromonadaceae 1236|Gammaproteobacteria H arginine decarboxylase speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3590,iE2348C_1286.E2348C_3191,iEC55989_1330.EC55989_3231,iECABU_c1320.ECABU_c32250,iECED1_1282.ECED1_3401,iECIAI1_1343.ECIAI1_3071,iECIAI39_1322.ECIAI39_3358,iECO103_1326.ECO103_3518,iECO26_1355.ECO26_4037,iECOK1_1307.ECOK1_3327,iECP_1309.ECP_2933,iECS88_1305.ECS88_3221,iECSE_1348.ECSE_3207,iECSF_1327.ECSF_2737,iECSP_1301.ECSP_3909,iECUMN_1333.ECUMN_3290,iECW_1372.ECW_m3198,iECs_1301.ECs3814,iEKO11_1354.EKO11_0788,iEcE24377_1341.EcE24377A_3281,iEcHS_1320.EcHS_A3096,iEcolC_1368.EcolC_0773,iG2583_1286.G2583_3597,iLF82_1304.LF82_2157,iNRG857_1313.NRG857_14440,iPC815.YPO0929,iSBO_1134.SBO_3051,iSDY_1059.SDY_3134,iSSON_1240.SSON_3092,iSbBS512_1146.SbBS512_E3371,iWFL_1372.ECW_m3198,iZ_1308.Z4283 Orn_Arg_deC_N k141_2982_2 1288826.MSNKSG1_17236 3.65e-220 606.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,46757@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_0125,iPC815.YPO3411,iSDY_1059.SDY_0028 Spermine_synt_N,Spermine_synth k141_2982_3 1288826.MSNKSG1_17241 5.88e-294 803.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,4652P@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_2982_5 1288826.MSNKSG1_17251 2.13e-47 152.0 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,46899@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane fusogenic activity yqiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09806 - - - - ko00000 - - - BMFP k141_2982_6 1288826.MSNKSG1_17256 5.08e-116 346.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,464ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATPase with chaperone activity comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_9910_1 396588.Tgr7_1240 8.27e-21 92.0 COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,1S88Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S amidohydrolase - - - - - - - - - - - - Amidohydro_2 k141_9910_4 498211.CJA_3357 2.75e-17 84.3 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1FGEW@10|Cellvibrio 1236|Gammaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD,HD_5 k141_5038_1 1255043.TVNIR_3114 2.8e-185 528.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales 135613|Chromatiales C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M k141_21771_1 472759.Nhal_1407 2.28e-60 217.0 COG0642@1|root,COG5001@1|root,COG2205@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WWRT@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - - - - - - - - - - DUF2222,EAL,GGDEF,HATPase_c,HisKA,Hpt,Response_reg k141_161_1 1165096.ARWF01000001_gene1288 5.04e-47 182.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,2KKXD@206350|Nitrosomonadales 206350|Nitrosomonadales O ResB-like family - - - ko:K07399 - - - - ko00000 - - - ResB k141_8556_2 743299.Acife_1479 8.41e-98 292.0 COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,1RYN3@1236|Gammaproteobacteria,2NDKN@225057|Acidithiobacillales 225057|Acidithiobacillales K WYL domain - - - - - - - - - - - - HTH_11,WYL k141_3678_1 1415778.JQMM01000001_gene1251 2.94e-07 53.1 2DP6U@1|root,330T2@2|Bacteria,1N7R9@1224|Proteobacteria,1SDI8@1236|Gammaproteobacteria,1JA9T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_OmpA,Gly-zipper_YMGG k141_3678_2 525318.HMPREF0497_0748 1.04e-17 81.3 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F6RF@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N k141_15559_2 1288826.MSNKSG1_16181 2.16e-133 390.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - - - - - - - - - - - PMT,PMT_2 k141_13444_1 1278309.KB907106_gene1232 2.02e-224 624.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria,1XIIE@135619|Oceanospirillales 135619|Oceanospirillales P amino acid ABC transporter aapQ - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_13444_2 1278309.KB907106_gene1233 6.09e-74 231.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria,1XIG0@135619|Oceanospirillales 135619|Oceanospirillales P Amino acid ABC transporter, permease aapM - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_16913_2 1121918.ARWE01000001_gene2831 3.34e-87 261.0 COG2755@1|root,COG2755@2|Bacteria,1RDVJ@1224|Proteobacteria 1224|Proteobacteria E lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL_2 k141_12739_1 1173263.Syn7502_00144 6.54e-51 176.0 COG0732@1|root,COG0732@2|Bacteria 2|Bacteria V type I restriction modification DNA specificity domain - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k141_12739_2 46429.BV95_00993 2.61e-33 126.0 COG3613@1|root,COG4271@1|root,COG3613@2|Bacteria,COG4271@2|Bacteria,1RFT4@1224|Proteobacteria,2UA59@28211|Alphaproteobacteria 28211|Alphaproteobacteria F DNA primase activity - - - - - - - - - - - - - k141_4374_2 1122212.AULO01000014_gene1185 1.14e-08 62.8 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1XMG0@135619|Oceanospirillales 135619|Oceanospirillales K ATP-dependent transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE k141_4374_3 765913.ThidrDRAFT_0792 1.44e-20 90.5 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_19702_1 1278309.KB907104_gene825 6.88e-28 118.0 2CAAX@1|root,309HW@2|Bacteria,1REWM@1224|Proteobacteria,1S4Y8@1236|Gammaproteobacteria,1XNDT@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_10663_1 631362.Thi970DRAFT_02219 4.95e-63 211.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_21772_1 1255043.TVNIR_1499 6.75e-09 57.4 COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1R6BM@1224|Proteobacteria,1RRQG@1236|Gammaproteobacteria,1WWNE@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,Response_reg k141_6442_1 1278309.KB907100_gene2098 2.45e-236 656.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XIG9@135619|Oceanospirillales 135619|Oceanospirillales P phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_6442_2 1278309.KB907100_gene2099 4.79e-190 533.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1XIMG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the peptidase M20A family. ArgE subfamily argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_8557_1 203122.Sde_0398 1.7e-68 229.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_12036_1 2340.JV46_24720 4.19e-37 129.0 COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,1JAGD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c soxX - - ko:K17223 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C,Cytochrome_CBB3 k141_7865_1 1278309.KB907109_gene3283 2.81e-166 480.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1XHEE@135619|Oceanospirillales 135619|Oceanospirillales P Chloride channel - - - - - - - - - - - - CBS,Voltage_CLC k141_7865_2 1278309.KB907109_gene3284 7.87e-74 229.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XHRU@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_13445_1 1396858.Q666_03595 1.76e-08 56.6 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,466JN@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE k141_13445_2 631454.N177_3817 7.44e-23 96.7 COG3181@1|root,COG3181@2|Bacteria,1NYMI@1224|Proteobacteria,2UTM7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k141_12740_1 472759.Nhal_0146 3.56e-75 240.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales 135613|Chromatiales K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase k141_21155_1 1122201.AUAZ01000009_gene2879 1.25e-46 164.0 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,465RR@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k141_21155_2 1049564.TevJSym_ax00490 1.82e-45 164.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k141_162_1 357804.Ping_2163 5.13e-83 270.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,2QIUT@267894|Psychromonadaceae 1236|Gammaproteobacteria M Bifunctional transglycosylase second domain mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k141_5801_2 402626.Rpic_0987 3.55e-42 147.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,1K0DX@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_9212_2 697282.Mettu_3160 3.24e-61 218.0 COG2202@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,GAF_2,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Hpt,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Phosphonate-bd,Reg_prop,Response_reg,TarH,Y_Y_Y k141_9212_3 525897.Dbac_0952 1.56e-91 283.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,42MWQ@68525|delta/epsilon subdivisions,2WM69@28221|Deltaproteobacteria,2MG2F@213115|Desulfovibrionales 28221|Deltaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_6443_1 1288826.MSNKSG1_11433 1.77e-73 241.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,468WP@72275|Alteromonadaceae 1236|Gammaproteobacteria I membrane-associated protein lssY - - ko:K03975 - - - - ko00000 - - - LssY_C,PAP2,SNARE_assoc k141_4375_1 1288826.MSNKSG1_08223 2.57e-173 493.0 2EIBS@1|root,33C35@2|Bacteria,1QVXE@1224|Proteobacteria,1SHEY@1236|Gammaproteobacteria,468VS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flagellar hook-length control protein FliK - - - - - - - - - - - - Flg_hook k141_12168_3 1278309.KB907100_gene2210 2.06e-151 429.0 COG2207@1|root,COG2207@2|Bacteria,1N70D@1224|Proteobacteria,1SCZK@1236|Gammaproteobacteria,1XJBU@135619|Oceanospirillales 135619|Oceanospirillales K COG2207 AraC-type DNA-binding domain-containing proteins - - - - - - - - - - - - AraC_binding,HTH_18 k141_19807_1 1288826.MSNKSG1_01678 2.71e-23 93.2 COG1266@1|root,COG1266@2|Bacteria,1R5RA@1224|Proteobacteria,1S0ZC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_19807_2 1288826.MSNKSG1_01683 3.4e-74 225.0 2CH3Z@1|root,32RP9@2|Bacteria,1MZF8@1224|Proteobacteria,1S8TF@1236|Gammaproteobacteria,468U3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2721) - - - - - - - - - - - - DUF2721 k141_11470_1 225937.HP15_1816 1.14e-82 255.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b k141_11470_2 1288826.MSNKSG1_06448 2.74e-108 317.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,465WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the precorrin methyltransferase family cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_15648_1 237609.PSAKL28_48800 1.38e-16 79.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis signal transduction protein chpC - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k141_15648_2 105559.Nwat_0113 3.89e-57 193.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1S0CW@1236|Gammaproteobacteria,1X2DN@135613|Chromatiales 135613|Chromatiales NT CheB methylesterase - - - ko:K06597 ko02020,map02020 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheB_methylest k141_19166_1 1049564.TevJSym_ad00780 2.36e-87 275.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_21936_1 1026882.MAMP_00009 2.95e-18 89.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,460ZY@72273|Thiotrichales 72273|Thiotrichales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k141_10032_1 870187.Thini_1186 3.62e-175 490.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,45ZUF@72273|Thiotrichales 72273|Thiotrichales S PFAM AAA domain (dynein-related subfamily) - - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_18424_1 1278309.KB907106_gene1382 2.53e-276 776.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1XHJB@135619|Oceanospirillales 135619|Oceanospirillales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_16305_1 754476.Q7A_1297 8.54e-33 134.0 COG0532@1|root,COG3064@1|root,COG0532@2|Bacteria,COG3064@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,45ZTR@72273|Thiotrichales 72273|Thiotrichales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N,IF2_assoc k141_21263_1 1288826.MSNKSG1_17935 0.0 1001.0 COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,464TU@72275|Alteromonadaceae 1236|Gammaproteobacteria NU pilus (MSHA type) biogenesis protein MshL mshL - - ko:K12282 - - - - ko00000,ko02044 - - - STN,Secretin,Secretin_N_2 k141_21263_2 1288826.MSNKSG1_17940 3.59e-95 283.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,465DA@72275|Alteromonadaceae 1236|Gammaproteobacteria U Type II secretory pathway, component ExeA mshM - - ko:K12283 - - - - ko00000,ko02044 - - - AAA_22 k141_5891_1 580332.Slit_2799 3.33e-79 242.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_6536_1 1278309.KB907101_gene534 1.3e-114 348.0 COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XHEH@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA rlmL - 2.1.1.173,2.1.1.264 ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 k141_6536_2 1042375.AFPL01000055_gene2248 3.61e-32 112.0 COG3130@1|root,COG3130@2|Bacteria,1N761@1224|Proteobacteria,1SCIC@1236|Gammaproteobacteria,468Z0@72275|Alteromonadaceae 1236|Gammaproteobacteria J During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) rmf GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032055,GO:0032268,GO:0032269,GO:0033554,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043555,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 - ko:K03812 - - - - ko00000,ko03009 - - - RMF k141_6536_3 1278309.KB907101_gene533 2.19e-212 590.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1XITP@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh k141_6536_4 1278309.KB907101_gene530 1.73e-153 449.0 COG4783@1|root,COG4783@2|Bacteria,1QTUQ@1224|Proteobacteria,1T1HY@1236|Gammaproteobacteria,1XRY3@135619|Oceanospirillales 135619|Oceanospirillales S Oxygen tolerance - - - - - - - - - - - - BatD k141_12877_1 1122619.KB892302_gene2488 8.68e-41 143.0 28J9Q@1|root,2Z94J@2|Bacteria,1N9VS@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_12877_2 1131553.JIBI01000056_gene155 2.39e-47 162.0 28J7S@1|root,2Z933@2|Bacteria,1R4RA@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_10792_1 870187.Thini_0135 5.22e-26 105.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,460E8@72273|Thiotrichales 72273|Thiotrichales J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_10792_2 1123399.AQVE01000020_gene1711 4.2e-17 83.6 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,463G0@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_5 k141_11471_1 1288826.MSNKSG1_10128 2.47e-38 128.0 2DQGT@1|root,336RW@2|Bacteria,1NDYA@1224|Proteobacteria,1SDC3@1236|Gammaproteobacteria,46BUD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3185) - - - - - - - - - - - - DUF3185 k141_11471_2 1288826.MSNKSG1_10123 2.65e-56 184.0 COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,466GD@72275|Alteromonadaceae 1236|Gammaproteobacteria S 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 k141_17763_1 43759.JNWK01000004_gene1047 4.62e-29 120.0 COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria 201174|Actinobacteria C Dehydrogenase lpd GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_4513_1 1123519.PSJM300_04090 8.26e-23 95.9 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1Z2ED@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 k141_4513_2 342610.Patl_3526 1.84e-05 47.0 COG3116@1|root,COG3116@2|Bacteria,1N9MH@1224|Proteobacteria,1SC7P@1236|Gammaproteobacteria,2Q2TU@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K03586 - - - - ko00000,ko03036 - - - FtsL k141_4513_3 396588.Tgr7_0763 2.1e-141 420.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k141_3134_1 935548.KI912159_gene6003 2.18e-32 132.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,43IG7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_3134_3 649764.HMPREF0762_01831 2.78e-07 53.5 COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CUAA@84998|Coriobacteriia 84998|Coriobacteriia J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB - - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C k141_8664_1 366394.Smed_1820 9.5e-16 78.6 2E03M@1|root,32VSF@2|Bacteria,1N1I1@1224|Proteobacteria,2UN7W@28211|Alphaproteobacteria,4BHDT@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_12170_1 1448139.AI20_18525 1.82e-111 348.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y479@135624|Aeromonadales 135624|Aeromonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k141_1730_1 1278309.KB907109_gene3242 2.4e-81 243.0 COG3045@1|root,COG3045@2|Bacteria,1RDI5@1224|Proteobacteria,1T060@1236|Gammaproteobacteria,1XJM1@135619|Oceanospirillales 135619|Oceanospirillales S CreA protein - - - ko:K05805 - - - - ko00000 - - - CreA k141_1730_2 1278309.KB907109_gene3241 0.0 1264.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XHJZ@135619|Oceanospirillales 135619|Oceanospirillales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_21937_1 1283300.ATXB01000002_gene3036 4.9e-83 261.0 COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria,1XF0I@135618|Methylococcales 135618|Methylococcales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - HDOD k141_21264_2 519989.ECTPHS_03267 3.1e-84 261.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1WWIR@135613|Chromatiales 135613|Chromatiales H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_10793_1 1288826.MSNKSG1_17441 7.7e-125 366.0 COG2067@1|root,COG2067@2|Bacteria,1RA6W@1224|Proteobacteria,1RPD8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2067 Long-chain fatty acid transport protein - - - - - - - - - - - - Toluene_X k141_2388_1 1288826.MSNKSG1_01483 6.72e-132 382.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,46759@72275|Alteromonadaceae 1236|Gammaproteobacteria CE COG0473 Isocitrate isopropylmalate dehydrogenase yeaU GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0006082,GO:0006108,GO:0008150,GO:0008152,GO:0009027,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_1288 Iso_dh k141_2388_2 1288826.MSNKSG1_01478 3.74e-121 347.0 2CFK9@1|root,2ZACR@2|Bacteria,1N5EA@1224|Proteobacteria,1S93H@1236|Gammaproteobacteria,4675U@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1439) - - - - - - - - - - - - DUF1439 k141_2388_3 1288826.MSNKSG1_01473 3.67e-41 135.0 2EGSV@1|root,33AIZ@2|Bacteria,1QAWM@1224|Proteobacteria,1T6BX@1236|Gammaproteobacteria,4690W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG k141_2388_4 1288826.MSNKSG1_01468 3.61e-19 85.1 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,465VR@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - 4.1.1.82 ko:K09459,ko:K10907 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_17024_1 1278309.KB907101_gene299 2.87e-278 765.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1XH7P@135619|Oceanospirillales 135619|Oceanospirillales F Deoxyguanosinetriphosphate triphosphohydrolase-like protein dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_17024_2 1278309.KB907101_gene298 1.95e-57 182.0 2EQTE@1|root,309FZ@2|Bacteria,1QSVM@1224|Proteobacteria,1RWG7@1236|Gammaproteobacteria,1XKZF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_3135_1 1288826.MSNKSG1_06828 2.4e-32 123.0 2B52F@1|root,31XVQ@2|Bacteria,1MYIZ@1224|Proteobacteria,1SPHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PEP-CTERM motif - - - - - - - - - - - - DUF4114,VPEP k141_19809_1 1278309.KB907104_gene817 4.47e-191 539.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1XH4E@135619|Oceanospirillales 135619|Oceanospirillales S type VI secretion protein - - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k141_19809_2 1278309.KB907104_gene818 9.27e-51 162.0 COG3518@1|root,COG3518@2|Bacteria,1RE8H@1224|Proteobacteria,1SDC0@1236|Gammaproteobacteria,1XMUP@135619|Oceanospirillales 135619|Oceanospirillales S Gene 25-like lysozyme - - - ko:K11905 - M00334 - - ko00000,ko00002,ko02044 - - - GPW_gp25 k141_8665_2 205922.Pfl01_0402 4.51e-28 111.0 COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S5D6@1236|Gammaproteobacteria,1YUKK@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria L Staphylococcal nuclease homologues - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - DUF4124,SNase k141_19167_1 1232683.ADIMK_4142 1.82e-138 397.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,46C5D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase mhpB - - - - - - - - - - - LigB k141_19167_2 491952.Mar181_1784 4.45e-37 130.0 COG0664@1|root,COG0664@2|Bacteria,1MZ52@1224|Proteobacteria,1SASM@1236|Gammaproteobacteria,1XKRK@135619|Oceanospirillales 135619|Oceanospirillales T cyclic nucleotide-binding - - - - - - - - - - - - cNMP_binding k141_5893_2 1469245.JFBG01000076_gene139 3.03e-100 297.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales 135613|Chromatiales O TIGRFAM FeS assembly ATPase SufC - - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_17025_1 1234364.AMSF01000024_gene3849 2.39e-112 332.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1X4F6@135614|Xanthomonadales 135614|Xanthomonadales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_20580_1 269799.Gmet_2352 1.02e-128 376.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C k141_19186_1 713587.THITH_06490 2.98e-26 100.0 2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,1S9XM@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19186_2 519989.ECTPHS_05741 5.27e-29 122.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RYYR@1236|Gammaproteobacteria,1X06T@135613|Chromatiales 135613|Chromatiales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF_2,GGDEF,PAS_3 k141_5178_1 1236959.BAMT01000001_gene1631 3.46e-161 464.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2WH9U@28216|Betaproteobacteria,2KME4@206350|Nitrosomonadales 206350|Nitrosomonadales I PFAM Carbamoyl-phosphate synthase L chain - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_5178_2 1219080.VEZ01S_07_00210 4.85e-14 73.9 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XTCK@135623|Vibrionales 135623|Vibrionales S metal-binding, possibly nucleic acid-binding protein yceD - - ko:K07040 - - - - ko00000 - - - DUF177 k141_7303_1 765912.Thimo_0969 5.51e-33 125.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1WX92@135613|Chromatiales 135613|Chromatiales D probably involved in intracellular septation - - - ko:K06190 - - - - ko00000 - - - IspA k141_7303_2 715451.ambt_11675 1.25e-46 151.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,467T6@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05527,ko:K09780 - - - - ko00000,ko03000 - - - YCII k141_7303_3 856793.MICA_1456 8.88e-40 148.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,4BQC7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O PPIC-type PPIASE domain ppiC - 5.2.1.8 ko:K01802,ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 k141_7303_5 1117319.PSPO_04187 2.73e-06 48.9 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,1RYM8@1236|Gammaproteobacteria,2Q4IN@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Glycosyltransferase like family 2 alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_8060_1 391615.ABSJ01000050_gene1176 5.46e-43 154.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1J7ED@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG1459 Type II secretory pathway, component PulF gspF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_19819_1 666685.R2APBS1_3004 2.34e-37 140.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1X3H3@135614|Xanthomonadales 135614|Xanthomonadales N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella fliC - - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_IN,Flagellin_N k141_1019_2 1189620.AJXL01000076_gene722 2.91e-07 53.1 2ERT0@1|root,33JC7@2|Bacteria,4NZ16@976|Bacteroidetes,1I6JX@117743|Flavobacteriia,2NXJR@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k141_11491_1 926554.KI912640_gene1366 1.47e-67 219.0 COG1960@1|root,COG1960@2|Bacteria,1WMGQ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N k141_1747_1 1121921.KB898708_gene1607 3.03e-14 72.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,2PMYF@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J tRNA synthetases class I (E and Q), anti-codon binding domain glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k141_13556_1 379731.PST_0056 2.33e-33 132.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNE@1236|Gammaproteobacteria,1Z1I6@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T COG2202 FOG PAS PAC domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,dCache_3 k141_8689_2 489653.NLA_6641 9.48e-43 141.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2VURH@28216|Betaproteobacteria,2KT9W@206351|Neisseriales 206351|Neisseriales L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG k141_4537_1 349521.HCH_02122 3.17e-51 172.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1XHER@135619|Oceanospirillales 135619|Oceanospirillales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_4537_2 519989.ECTPHS_03994 2.88e-24 101.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1WXGJ@135613|Chromatiales 135613|Chromatiales G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k141_15662_1 1385517.N800_11170 1.49e-07 53.1 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1X4H1@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_15662_2 1286106.MPL1_05779 4.61e-157 449.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,46040@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_19187_1 266117.Rxyl_1613 1.58e-05 47.0 COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2H0W0@201174|Actinobacteria 201174|Actinobacteria C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD k141_19187_2 290317.Cpha266_0120 2.05e-54 190.0 COG0243@1|root,COG0243@2|Bacteria,1FDP0@1090|Chlorobi 1090|Chlorobi C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_6556_1 765910.MARPU_04845 1.22e-54 191.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1WX0K@135613|Chromatiales 135613|Chromatiales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_333_1 713587.THITH_14700 9.47e-12 64.7 COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,1S2TH@1236|Gammaproteobacteria,1WY0K@135613|Chromatiales 135613|Chromatiales S PFAM Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans k141_333_2 400668.Mmwyl1_2336 1.1e-47 157.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1XKHG@135619|Oceanospirillales 135619|Oceanospirillales FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - - - - - - - - - - HIT k141_333_3 1131553.JIBI01000017_gene577 1.3e-24 103.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales 28216|Betaproteobacteria L RNA polymerase recycling family C-terminal - - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N k141_11492_1 1278309.KB907107_gene1641 3.14e-81 253.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria,1XRHB@135619|Oceanospirillales 135619|Oceanospirillales T Forkhead associated domain - - - ko:K11894 - - - - ko00000,ko02044 3.A.23.1 - - FHA k141_18435_1 1123517.JOMR01000001_gene1922 2.97e-62 211.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4603G@72273|Thiotrichales 72273|Thiotrichales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_18435_2 580332.Slit_2159 1.9e-31 124.0 COG2206@1|root,COG2206@2|Bacteria,1MWDU@1224|Proteobacteria,2VIAF@28216|Betaproteobacteria,44W5K@713636|Nitrosomonadales 28216|Betaproteobacteria T PFAM metal-dependent phosphohydrolase HD sub domain - - - - - - - - - - - - HD_5 k141_2413_1 580332.Slit_2512 7.17e-105 323.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales 28216|Betaproteobacteria V PFAM ABC transporter related - - - ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC_tran k141_2413_2 580332.Slit_2511 4.7e-81 254.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2VH7G@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM secretion protein HlyD family protein - - - ko:K01993,ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_2413_3 1116375.VEJY3_21651 2.87e-71 228.0 COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits - - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k141_14958_1 1328313.DS2_09547 5.94e-34 141.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,466MR@72275|Alteromonadaceae 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_8769_5 1288826.MSNKSG1_04226 7.73e-37 124.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,468BS@72275|Alteromonadaceae 1236|Gammaproteobacteria T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k141_10200_1 713586.KB900536_gene1413 1.22e-142 411.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales 135613|Chromatiales M Arabinose 5-phosphate isomerase - - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k141_18563_1 140626.JHWB01000009_gene1669 6.98e-13 71.6 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia 186801|Clostridia P Transporter, CPA2 family napA - - - - - - - - - - - Na_H_Exchanger k141_8186_2 1120953.AUBH01000004_gene2964 7.73e-64 199.0 COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,1SZJ5@1236|Gammaproteobacteria,46B6Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C Globin - - - - - - - - - - - - Globin k141_5350_1 1283300.ATXB01000001_gene573 3.44e-37 129.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1XF5X@135618|Methylococcales 135618|Methylococcales S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY k141_5350_2 472759.Nhal_0034 3.65e-31 110.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1WZDN@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bS21 family rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k141_3911_1 298386.PBPRB0645 1.43e-128 384.0 COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria 1224|Proteobacteria C COG0348 Polyferredoxin vnfA - - - - - - - - - - - Fer4_5 k141_18580_1 1087481.AGFX01000023_gene2245 8.57e-67 205.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,26ZF2@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k141_10217_1 1242864.D187_009230 2.13e-21 99.8 COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,43DHZ@68525|delta/epsilon subdivisions,2X8PR@28221|Deltaproteobacteria,2Z1U9@29|Myxococcales 1224|Proteobacteria S Porin subfamily - - - - - - - - - - - - Porin_2 k141_1877_1 670292.JH26_24975 1.2e-38 137.0 COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_490_1 1469613.JT55_19140 8.13e-85 265.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,3FCS4@34008|Rhodovulum 28211|Alphaproteobacteria F AICARFT/IMPCHase bienzyme purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS k141_4683_1 998674.ATTE01000001_gene2185 2.13e-77 236.0 COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,1RRAF@1236|Gammaproteobacteria,461JC@72273|Thiotrichales 72273|Thiotrichales S Lysine methyltransferase - - - - - - - - - - - - Methyltransf_16 k141_11616_1 1288826.MSNKSG1_18010 2.58e-107 310.0 2AFX8@1|root,3160N@2|Bacteria,1QE3Z@1224|Proteobacteria,1TAFT@1236|Gammaproteobacteria,4691A@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k141_11616_2 1288826.MSNKSG1_18005 1.88e-118 347.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,46416@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase, nitrogen specific glnL GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_7454_1 1121479.AUBS01000005_gene2680 2.59e-73 244.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 k141_13062_1 1288826.MSNKSG1_04491 1.04e-139 396.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae 1236|Gammaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 OMPdecase k141_13062_2 1288826.MSNKSG1_04486 2.41e-278 761.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,4664S@72275|Alteromonadaceae 1236|Gammaproteobacteria G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7,TPR_8 k141_13062_3 1288826.MSNKSG1_04481 2.13e-43 143.0 COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria,468XT@72275|Alteromonadaceae 1236|Gammaproteobacteria S Lipopolysaccharide assembly protein A domain - - - ko:K08992 - - - - ko00000 - - - LapA_dom k141_13062_4 1288826.MSNKSG1_04476 9.59e-64 194.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,467QW@72275|Alteromonadaceae 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_13062_5 1288826.MSNKSG1_04471 0.0 1067.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,464BF@72275|Alteromonadaceae 1236|Gammaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k141_13062_6 1288826.MSNKSG1_04466 8.59e-141 399.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,466NJ@72275|Alteromonadaceae 1236|Gammaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO1391,iSDY_1059.SDY_2348 Cytidylate_kin k141_5999_1 396588.Tgr7_2031 1.35e-71 225.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1WVZF@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR k141_17181_1 1380367.JIBC01000004_gene2340 1.11e-71 219.0 COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria,3ZX27@60136|Sulfitobacter 28211|Alphaproteobacteria K Crp-like helix-turn-helix domain - - - ko:K01420,ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding k141_8779_1 391613.RTM1035_16322 2.92e-91 293.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,46NJA@74030|Roseovarius 28211|Alphaproteobacteria L COG1643 HrpA-like helicases hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C k141_1204_1 227377.CBU_1520 6.84e-18 78.2 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1JEYK@118969|Legionellales 118969|Legionellales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grx - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_15081_1 1278309.KB907100_gene2073 2.1e-85 256.0 2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15081_2 1278309.KB907100_gene2074 4.94e-126 362.0 COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1XJ8K@135619|Oceanospirillales 135619|Oceanospirillales S hydrolase - - 3.1.3.102,3.1.3.104 ko:K20862 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 k141_491_1 765913.ThidrDRAFT_3356 3.21e-80 262.0 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales 135613|Chromatiales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k141_16477_1 1121926.AXWO01000002_gene1368 8.98e-05 47.8 COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria 201174|Actinobacteria G polysaccharide deacetylase xynD - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - CBM_2,Polysacc_deac_1 k141_2540_1 1188256.BASI01000005_gene2160 5.42e-09 56.2 COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,3FCQG@34008|Rhodovulum 28211|Alphaproteobacteria EGP Major Facilitator Superfamily MA20_42180 - - - - - - - - - - - MFS_1 k141_2540_2 1123360.thalar_03406 1.21e-125 371.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ATPase, AFG1 family zapE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k141_15839_1 1288826.MSNKSG1_11063 2.33e-129 371.0 COG3336@1|root,COG3336@2|Bacteria,1RAW2@1224|Proteobacteria,1S3HN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - ko:K02351 - - - - ko00000 - - - Caa3_CtaG k141_4684_1 1163617.SCD_n00315 1.7e-62 207.0 COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - k141_13745_1 1288826.MSNKSG1_13732 3.73e-129 376.0 COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,1T1TS@1236|Gammaproteobacteria,468B3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 k141_18582_1 519989.ECTPHS_02359 1.13e-50 182.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales 135613|Chromatiales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_17182_1 371731.Rsw2DRAFT_3277 4.67e-26 103.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,1FBEX@1060|Rhodobacter 28211|Alphaproteobacteria H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_17182_2 1122180.Lokhon_00809 1.15e-33 128.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2P8HV@245186|Loktanella 28211|Alphaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_5373_1 1278309.KB907103_gene1084 9.77e-72 231.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XI1K@135619|Oceanospirillales 135619|Oceanospirillales I Poly(3-hydroxyalkanoate) synthetase - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N k141_5373_2 1123053.AUDG01000016_gene3359 3.16e-06 48.1 COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria,1SGAT@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins XAC3035 - - - - - - - - - - - DUF836 k141_3298_2 545276.KB898725_gene837 9e-130 381.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X2HB@135613|Chromatiales 135613|Chromatiales M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k141_6000_1 296591.Bpro_5311 4.54e-40 144.0 COG3121@1|root,COG3121@2|Bacteria,1RFSJ@1224|Proteobacteria,2VQ6I@28216|Betaproteobacteria,4AGVT@80864|Comamonadaceae 28216|Betaproteobacteria NU COG3121 P pilus assembly protein, chaperone PapD - - - - - - - - - - - - PapD_N k141_10219_1 1336245.JAGO01000012_gene1860 1e-31 125.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_19955_2 1158292.JPOE01000002_gene3358 2.45e-33 122.0 COG1651@1|root,COG1651@2|Bacteria,1NEFD@1224|Proteobacteria,2VKFR@28216|Betaproteobacteria 28216|Betaproteobacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbG - - ko:K03805 - - - - ko00000,ko03110 - - - Thioredoxin_2 k141_11617_1 323261.Noc_2432 4.2e-87 268.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1X2FT@135613|Chromatiales 135613|Chromatiales S PFAM Aminoglycoside phosphotransferase - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_1205_2 1123368.AUIS01000003_gene1714 2.08e-12 63.2 2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,1SHMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cbb3-type cytochrome oxidase component FixQ - - - - - - - - - - - - FixQ k141_1205_3 2340.JV46_27920 5.51e-48 160.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1J4Y9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_1878_1 1395571.TMS3_0124375 4.54e-35 125.0 COG1943@1|root,COG1943@2|Bacteria,1MZZT@1224|Proteobacteria,1S9JG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - Y1_Tnp k141_1878_2 396588.Tgr7_2778 5.51e-55 194.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_16478_1 396014.BF93_17225 2.28e-12 67.8 COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4FDS9@85020|Dermabacteraceae 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_16478_2 1408452.JAGZ01000002_gene4222 0.000592 47.0 COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,2348E@1762|Mycobacteriaceae 201174|Actinobacteria T Histidine kinase - - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c k141_21413_1 1260251.SPISAL_03125 3.87e-59 212.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_21413_2 396588.Tgr7_0993 2.85e-38 139.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_8195_2 443598.AUFA01000051_gene46 3.04e-20 92.8 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TQPQ@28211|Alphaproteobacteria,3JRXB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain hprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_19327_1 1278309.KB907100_gene2113 4.33e-43 146.0 COG3907@1|root,COG3907@2|Bacteria,1QV68@1224|Proteobacteria,1SC79@1236|Gammaproteobacteria,1XKEF@135619|Oceanospirillales 135619|Oceanospirillales S PAP2 superfamily - - - ko:K12978 - - - - ko00000,ko01000,ko01005 - - - PAP2 k141_19327_2 1123401.JHYQ01000006_gene62 5.46e-137 394.0 COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,1RRMA@1236|Gammaproteobacteria 1236|Gammaproteobacteria E transglutaminase-like - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_19327_3 498211.CJA_0994 2.21e-103 307.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1RNV8@1236|Gammaproteobacteria,1FGFT@10|Cellvibrio 1236|Gammaproteobacteria E Transglutaminase/protease-like homologues - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_17928_1 323261.Noc_2374 1.61e-44 151.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1WWVR@135613|Chromatiales 135613|Chromatiales N TIGRFAM flagellar basal-body rod protein FlgF - - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_17928_2 1117647.M5M_02220 4.73e-39 146.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1J50K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_17183_1 1423144.Gal_02264 8.94e-26 111.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2TST4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k141_10220_1 1117315.AHCA01000012_gene2675 1.78e-96 290.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,2Q003@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_19956_1 571166.KI421509_gene1304 1.89e-136 399.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k141_1206_1 236097.ADG881_2815 4.99e-112 339.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1XI53@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_4686_1 479432.Sros_6464 4.78e-15 77.8 COG1309@1|root,COG1309@2|Bacteria,2GNBS@201174|Actinobacteria,4EK2F@85012|Streptosporangiales 201174|Actinobacteria K Tetracyclin repressor, C-terminal all-alpha domain - - - - - - - - - - - - TetR_C,TetR_N k141_4686_2 1096546.WYO_5251 0.000133 43.9 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q cytochrome P450 MA20_16700 - 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 k141_17184_1 582744.Msip34_2499 6.65e-78 244.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,2KKU8@206350|Nitrosomonadales 206350|Nitrosomonadales F Belongs to the dGTPase family. Type 2 subfamily - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc k141_13064_1 887062.HGR_10937 5.29e-59 187.0 COG3832@1|root,COG3832@2|Bacteria,1RJ9N@1224|Proteobacteria,2VVDA@28216|Betaproteobacteria,4AF30@80864|Comamonadaceae 28216|Betaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 k141_13064_2 371042.NG99_14560 6.03e-45 151.0 COG1733@1|root,COG1733@2|Bacteria,1R6HM@1224|Proteobacteria,1SEM2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_16480_1 686340.Metal_3442 3.21e-47 162.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XEAU@135618|Methylococcales 135618|Methylococcales F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_16480_2 999141.GME_07171 1.45e-09 59.3 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1XIIP@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the TrpC family trpC - 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS k141_2542_1 631362.Thi970DRAFT_01216 4.94e-30 109.0 COG3450@1|root,COG3450@2|Bacteria,1N8CD@1224|Proteobacteria,1SAR6@1236|Gammaproteobacteria,1X27X@135613|Chromatiales 135613|Chromatiales S enzyme of the cupin superfamily - - - ko:K06995 - - - - ko00000 - - - Cupin_3 k141_15843_1 743720.Psefu_3981 3.91e-49 171.0 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1YV27@136845|Pseudomonas putida group 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_7457_1 1278309.KB907100_gene2331 8.44e-60 209.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHMP@135619|Oceanospirillales 135619|Oceanospirillales T Chemotaxis protein histidine kinase and related - - - - - - - - - - - - CheW,HATPase_c,Hpt,Response_reg k141_7457_2 1278309.KB907100_gene2330 3.32e-91 287.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIUV@135619|Oceanospirillales 135619|Oceanospirillales NT chemotaxis protein - - - - - - - - - - - - HAMP,MCPsignal k141_15084_1 572477.Alvin_2897 4.63e-71 219.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1WWJX@135613|Chromatiales 135613|Chromatiales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like k141_15084_2 1149133.ppKF707_5328 2.58e-15 73.9 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1YEJT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_494_1 1122194.AUHU01000005_gene1027 1.46e-16 77.0 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,464SB@72275|Alteromonadaceae 1236|Gammaproteobacteria N Flagellar basal body rod protein flgF - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_494_2 1168065.DOK_02511 3.08e-61 203.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1J50K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_6002_1 493475.GARC_5203 2.27e-115 343.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,4658H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE k141_6002_2 1177179.A11A3_00045 2.7e-08 55.5 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,1XN39@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16481_1 314278.NB231_13146 7.05e-55 181.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1WW3W@135613|Chromatiales 135613|Chromatiales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k141_9589_3 1266925.JHVX01000008_gene257 1.15e-113 332.0 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria 28216|Betaproteobacteria L Transposase - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_21537_1 314345.SPV1_06539 2.73e-132 394.0 COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria 1224|Proteobacteria K UPF0761 membrane protein rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB k141_19428_1 1288826.MSNKSG1_05071 4.1e-90 268.0 COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1RSIE@1236|Gammaproteobacteria,46AD9@72275|Alteromonadaceae 1236|Gammaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD_2 k141_19428_2 1288826.MSNKSG1_05066 3.01e-55 176.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,466ZT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF924 k141_6138_1 1121904.ARBP01000006_gene3955 6.87e-20 84.7 2DCS6@1|root,2ZF4U@2|Bacteria,4P8QB@976|Bacteroidetes,47X2E@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_11089_1 491952.Mar181_2984 2.29e-88 274.0 COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,1RY9G@1236|Gammaproteobacteria,1XI44@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3419_1 1123073.KB899244_gene280 4.68e-19 87.4 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1X34V@135614|Xanthomonadales 135614|Xanthomonadales L the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 k141_3419_2 391615.ABSJ01000050_gene1237 2.38e-79 243.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1J5UI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin k141_3419_3 1397527.Q670_09095 6.3e-26 105.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1XH57@135619|Oceanospirillales 135619|Oceanospirillales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_13193_1 1196095.GAPWK_0896 6.47e-05 47.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_13193_2 69328.PVLB_21895 2.75e-14 72.4 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 PseudoU_synth_2,S4 k141_8328_1 1288826.MSNKSG1_02921 5.44e-77 244.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,464CV@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K03451 - - - - ko00000 2.A.15 - - BCCT k141_8328_2 1288826.MSNKSG1_02926 2.66e-220 608.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,464QG@72275|Alteromonadaceae 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) PA1766 - - - - - - - - - - - ATPgrasp_ST k141_8328_3 1288826.MSNKSG1_02931 7.14e-251 696.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,465H1@72275|Alteromonadaceae 1236|Gammaproteobacteria E 7 transmembrane helices usually fused to an inactive transglutaminase IV02_00930 - - - - - - - - - - - 7TM_transglut,Transglut_i_TM k141_18089_1 713586.KB900536_gene793 6.83e-29 114.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_18089_2 1249627.D779_1541 4.56e-228 644.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales 135613|Chromatiales CI TIGRFAM Oxaloacetate decarboxylase, alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA k141_1335_1 296591.Bpro_4279 4.88e-33 131.0 COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria 28216|Betaproteobacteria E Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth k141_8892_1 644801.Psest_3264 4.48e-130 392.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1Z0RF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_8892_2 87626.PTD2_07339 1e-82 263.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,2Q0X8@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_10361_2 644801.Psest_2115 8.21e-33 125.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1Z0YB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - - - - - - - - - - ABC_tran,ABC_tran_Xtn k141_4809_1 1173264.KI913949_gene2364 2.49e-33 126.0 COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria,1H8UZ@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - DinB_2,FGE-sulfatase k141_4809_2 1492922.GY26_02425 1.65e-25 100.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1S3NG@1236|Gammaproteobacteria,1JB67@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_8329_1 545276.KB898729_gene1533 2.05e-08 56.6 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1WWNM@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt k141_18090_1 391735.Veis_2907 2.18e-90 293.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,4A9UC@80864|Comamonadaceae 28216|Betaproteobacteria EQ 5-oxoprolinase oplaH - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_2669_1 640081.Dsui_3143 3.5e-08 59.3 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,2KWMY@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF4115) - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 k141_2669_2 187272.Mlg_1250 3.81e-41 149.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV pilus biogenesis stability protein PilW - - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_2669_3 343509.SG1763 7.44e-09 56.2 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_15170_1 1278309.KB907099_gene2783 1.42e-48 165.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XIS7@135619|Oceanospirillales 135619|Oceanospirillales E D-amino acid dehydrogenase dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_15170_2 1278309.KB907099_gene2784 7.68e-26 97.8 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XJX9@135619|Oceanospirillales 135619|Oceanospirillales J endoribonuclease - - - - - - - - - - - - Ribonuc_L-PSP k141_6140_1 1265505.ATUG01000002_gene1853 1.13e-20 95.9 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PKS@68525|delta/epsilon subdivisions,2WJBK@28221|Deltaproteobacteria,2MHTB@213118|Desulfobacterales 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg k141_8893_1 1122201.AUAZ01000005_gene630 7.81e-65 204.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RS6V@1236|Gammaproteobacteria,464BY@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - 4.1.1.77 ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R05374 RC00751,RC02672 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k141_8893_2 1137799.GZ78_07340 1.17e-29 114.0 COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1XISV@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds - - 4.1.3.39,4.1.3.43 ko:K01666,ko:K18365 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750,R05298 RC00307,RC00371,RC00572 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k141_3420_1 697282.Mettu_3961 1.66e-57 191.0 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1SXXS@1236|Gammaproteobacteria,1XGB3@135618|Methylococcales 135618|Methylococcales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_11091_1 292414.TM1040_0860 9.38e-114 338.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,4NAB5@97050|Ruegeria 28211|Alphaproteobacteria H 5-aminolevulinic acid synthase hemA - 2.3.1.37 ko:K00643 ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110 - R00830 RC00004,RC02815 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_609_1 207954.MED92_12104 2.07e-140 402.0 COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XI8C@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter permease - - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 k141_609_2 1122599.AUGR01000023_gene4139 1.87e-86 263.0 COG2113@1|root,COG2113@2|Bacteria,1MVXS@1224|Proteobacteria,1RQ3U@1236|Gammaproteobacteria,1XIM7@135619|Oceanospirillales 135619|Oceanospirillales E ABC transporter substrate-binding protein - - - - - - - - - - - - OpuAC k141_13886_1 314232.SKA53_00080 5.26e-95 291.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2P9BJ@245186|Loktanella 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_4819_1 545276.KB898725_gene792 3.08e-09 57.8 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales 135613|Chromatiales T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_4819_2 391008.Smal_0950 5.98e-30 116.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1X3TG@135614|Xanthomonadales 135614|Xanthomonadales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 k141_1989_1 1410608.JNKX01000018_gene2834 7.71e-16 81.6 COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,2FNHQ@200643|Bacteroidia,4AMBU@815|Bacteroidaceae 976|Bacteroidetes M Sulfatase - - - - - - - - - - - - Sulfatase k141_1989_2 1121413.JMKT01000014_gene2634 7.55e-07 54.7 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria,2MGVV@213115|Desulfovibrionales 28221|Deltaproteobacteria NT Two component signalling adaptor domain cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_19442_1 443152.MDG893_05804 3.83e-187 537.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,46435@72275|Alteromonadaceae 1236|Gammaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon k141_10381_1 926549.KI421517_gene2131 5.9e-39 146.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz k141_10381_2 742817.HMPREF9449_01512 3.44e-05 45.8 COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,2FNRW@200643|Bacteroidia,22YBK@171551|Porphyromonadaceae 976|Bacteroidetes GM COG4464 Capsular polysaccharide biosynthesis protein - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - k141_18107_1 290512.Paes_2185 8.33e-166 476.0 COG0161@1|root,COG0161@2|Bacteria,1FDPN@1090|Chlorobi 1090|Chlorobi H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_18107_2 396588.Tgr7_0755 1.81e-106 322.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WXBN@135613|Chromatiales 135613|Chromatiales C PFAM FAD linked oxidase domain protein - - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_22218_1 1538295.JY96_03475 1.48e-33 134.0 COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VJS8@28216|Betaproteobacteria 28216|Betaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k141_3430_1 318167.Sfri_0905 4.06e-06 51.2 2C39R@1|root,32UYY@2|Bacteria,1NMIM@1224|Proteobacteria,1SFZP@1236|Gammaproteobacteria,2QC0N@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1353_1 1211114.ALIP01000003_gene2789 2.72e-65 203.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1X6PT@135614|Xanthomonadales 135614|Xanthomonadales S phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - - - - - - - - - - Macro k141_1353_2 1117318.PRUB_07985 2.53e-41 141.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,2Q2GH@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Stringent starvation protein B sspB GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - ko:K03600 - - - - ko00000,ko03021 - - - SspB k141_1353_3 1524467.IV04_11150 1.39e-84 256.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,4001J@613|Serratia 1236|Gammaproteobacteria O Belongs to the GST superfamily sspA GO:0001000,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0008150,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0042594,GO:0043175,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N,GST_N_3 k141_1353_4 1304883.KI912532_gene1722 1.23e-18 83.6 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,2KUIS@206389|Rhodocyclales 206389|Rhodocyclales P Cytochrome C1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 k141_16623_1 1048983.EL17_13740 0.000209 44.7 COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA,PD40,TPR_16,TPR_2,TPR_8 k141_16623_2 227086.JGI_V11_53533 1.35e-89 273.0 COG0151@1|root,KOG0237@2759|Eukaryota 2759|Eukaryota F phosphoribosylamine-glycine ligase activity - - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_8340_1 1219065.VPR01S_05_02430 4.33e-51 166.0 COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,1S6DF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 k141_8340_2 1380394.JADL01000001_gene2134 9.09e-51 166.0 COG4319@1|root,COG4319@2|Bacteria,1N0SJ@1224|Proteobacteria,2UBCC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_3 k141_610_1 565045.NOR51B_828 1.74e-45 161.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1J6ZG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3,Phe_hydrox_dim k141_9608_2 228410.NE0874 1.32e-166 474.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,371XV@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k141_11720_1 1288826.MSNKSG1_09453 0.0 1036.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,46672@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) atuC - 6.4.1.5 ko:K13778 ko00281,map00281 - R03494 RC00367,RC00942 ko00000,ko00001,ko01000 - - - Carboxyl_trans k141_11720_2 1288826.MSNKSG1_09448 5.95e-203 562.0 COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,466BV@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) atuB - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 k141_11720_3 1288826.MSNKSG1_09443 8.31e-284 785.0 COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,1RR9Q@1236|Gammaproteobacteria,465U3@72275|Alteromonadaceae 1236|Gammaproteobacteria E Pfam:DUF1446 atuA - - - - - - - - - - - AtuA k141_4820_1 748658.KB907313_gene2380 4.85e-49 175.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_20781_1 1244869.H261_19546 1.51e-77 243.0 COG0847@1|root,COG0847@2|Bacteria,1MXM2@1224|Proteobacteria,2TUYC@28211|Alphaproteobacteria,2JVST@204441|Rhodospirillales 204441|Rhodospirillales L EXOIII - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_13887_1 1198232.CYCME_1941 1.03e-98 301.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,45ZNJ@72273|Thiotrichales 72273|Thiotrichales S Flavin containing amine oxidoreductase - - - ko:K06954 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_8916_1 1288826.MSNKSG1_06213 5.26e-109 320.0 COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,1S3X1@1236|Gammaproteobacteria,46BAC@72275|Alteromonadaceae 1236|Gammaproteobacteria S NAD FAD-dependent oxidoreductase - - - ko:K06955 - - - - ko00000 - - - Amino_oxidase,NAD_binding_8 k141_3431_1 983920.Y88_0466 4.94e-33 132.0 COG4206@1|root,COG4206@2|Bacteria,1R1JF@1224|Proteobacteria,2TZ3C@28211|Alphaproteobacteria,2KEQP@204457|Sphingomonadales 204457|Sphingomonadales H TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_2685_1 1288826.MSNKSG1_01738 0.000206 42.4 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SC7S@1236|Gammaproteobacteria,46931@72275|Alteromonadaceae 1236|Gammaproteobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase k141_2685_2 1288826.MSNKSG1_01733 2.3e-155 439.0 COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,1S1XJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_2685_3 1288826.MSNKSG1_01728 1.56e-152 429.0 COG0300@1|root,COG0300@2|Bacteria,1QUVN@1224|Proteobacteria,1T22I@1236|Gammaproteobacteria,466JC@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family csgA - - - - - - - - - - - adh_short k141_2685_4 1288826.MSNKSG1_01723 2.55e-69 209.0 2DQ92@1|root,335D5@2|Bacteria,1NG6T@1224|Proteobacteria,1SFWE@1236|Gammaproteobacteria,468WM@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_2685_5 1288826.MSNKSG1_01718 5.57e-187 525.0 COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,469KP@72275|Alteromonadaceae 1236|Gammaproteobacteria I alpha/beta hydrolase fold - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 k141_10382_1 1163409.UUA_10191 1.32e-43 144.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria,1X8PD@135614|Xanthomonadales 135614|Xanthomonadales L endonuclease containing a URI domain - - - - - - - - - - - - GIY-YIG k141_10382_2 247634.GPB2148_3515 3.6e-34 127.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1J4EQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Aminotran_3 k141_12526_1 296591.Bpro_1929 4.63e-47 163.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VSS4@28216|Betaproteobacteria 28216|Betaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k141_13211_2 1278309.KB907100_gene2083 1.78e-83 253.0 COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,1RQYV@1236|Gammaproteobacteria,1XIDK@135619|Oceanospirillales 135619|Oceanospirillales C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_16624_1 999541.bgla_1g28510 3.6e-51 176.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,1K2ZA@119060|Burkholderiaceae 28216|Betaproteobacteria L DNA photolyase phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k141_22220_1 935863.AWZR01000001_gene1608 1.25e-55 182.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,1X4H4@135614|Xanthomonadales 135614|Xanthomonadales S Alpha beta - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 k141_18109_1 493475.GARC_4908 3.26e-15 79.3 2CFU9@1|root,2Z9XM@2|Bacteria,1NBVN@1224|Proteobacteria,1T19G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_611_1 1266998.ATUJ01000022_gene3 2.18e-125 369.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,2PW41@265|Paracoccus 28211|Alphaproteobacteria F Amidohydrolase family - - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1,Urease_alpha k141_5603_2 986075.CathTA2_1839 6.2e-71 240.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HBPX@91061|Bacilli 91061|Bacilli P COG1178 ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k141_23_1 396588.Tgr7_0360 4.37e-127 372.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1WW3A@135613|Chromatiales 135613|Chromatiales F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N k141_18146_1 1485545.JQLW01000006_gene457 3.4e-31 120.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria 1224|Proteobacteria O Peptidase M48 agmM - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N k141_18146_2 713586.KB900536_gene186 4.94e-29 107.0 COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SF76@1236|Gammaproteobacteria,1WZJF@135613|Chromatiales 135613|Chromatiales C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 k141_18146_3 323848.Nmul_A0712 4.56e-36 125.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,373A7@32003|Nitrosomonadales 28216|Betaproteobacteria H diol metabolic process - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_18146_4 1042377.AFPJ01000032_gene2802 1.98e-45 160.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,464F3@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675 RsgA_GTPase k141_20944_1 1278309.KB907102_gene170 1.54e-76 234.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XIZ0@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_20944_2 1278309.KB907102_gene171 4.45e-171 483.0 COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1XJ99@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_1420_1 715451.ambt_00100 5.42e-56 187.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,464VA@72275|Alteromonadaceae 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N k141_2814_1 1408445.JHXP01000011_gene858 2.62e-22 96.3 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1JCZQ@118969|Legionellales 118969|Legionellales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB k141_2814_2 930169.B5T_00457 1.48e-05 45.4 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,1S9HX@1236|Gammaproteobacteria,1XPEX@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Cupredoxin_1 k141_11193_1 1123360.thalar_02940 1.13e-96 295.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria 28211|Alphaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_2118_1 501479.ACNW01000091_gene2215 6.58e-102 316.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_9089_2 261292.Nit79A3_2912 2.21e-19 83.2 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,37347@32003|Nitrosomonadales 28216|Betaproteobacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - - k141_20254_1 330214.NIDE1491 4.93e-31 125.0 COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae 40117|Nitrospirae T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - ABC_sub_bind,HATPase_c,HisKA_3,PAS_9 k141_20254_2 472759.Nhal_1438 1.68e-47 155.0 COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,1T2RG@1236|Gammaproteobacteria,1X15Y@135613|Chromatiales 135613|Chromatiales T cheY-homologous receiver domain - - - ko:K02485 - - - - ko00000,ko02022 - - - Response_reg k141_17443_1 713586.KB900536_gene2586 1.71e-99 321.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,1WWYS@135613|Chromatiales 135613|Chromatiales C FAD linked - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_17443_2 396588.Tgr7_2753 6.82e-29 109.0 COG3193@1|root,COG3193@2|Bacteria,1REZG@1224|Proteobacteria,1S5K5@1236|Gammaproteobacteria,1WYDR@135613|Chromatiales 135613|Chromatiales S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_12578_1 1278309.KB907100_gene1887 1.56e-194 560.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales 135619|Oceanospirillales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV k141_5604_1 1288826.MSNKSG1_10208 2.6e-40 139.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,469W8@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpaG - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_5214,iEcHS_1320.EcHS_A4584 FAA_hydrolase k141_5604_2 1288826.MSNKSG1_10213 2.3e-117 348.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,46A84@72275|Alteromonadaceae 1236|Gammaproteobacteria C Aldehyde dehydrogenase family hpaE - 1.2.1.60 ko:K00151 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04418 RC00254 ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_04787 Aldedh k141_18859_1 1121918.ARWE01000001_gene3562 1.34e-82 251.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria 1224|Proteobacteria Q Methyl-transferase - - - - - - - - - - - - Methyltransf_25,Methyltransf_31,Ubie_methyltran k141_18147_1 1278309.KB907102_gene186 1.36e-11 63.5 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XIX4@135619|Oceanospirillales 135619|Oceanospirillales T Bacterial regulatory protein, Fis family - - - ko:K10126 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_18147_2 1278309.KB907102_gene185 3.36e-68 227.0 COG4191@1|root,COG4191@2|Bacteria,1R4YU@1224|Proteobacteria,1RSG2@1236|Gammaproteobacteria,1XI49@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 k141_21632_1 857087.Metme_4135 7.14e-65 228.0 COG2203@1|root,COG3850@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XG4R@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S) - - - - - - - - - - - - EAL,GAF_2,GGDEF,HAMP,PAS_9,sCache_3_2 k141_16053_3 1396418.BATQ01000043_gene6417 2.24e-11 69.7 COG2373@1|root,COG2373@2|Bacteria,46TFK@74201|Verrucomicrobia,2IVBC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Alpha-2-macroglobulin MG1 domain - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,MG1 k141_6293_1 349965.yinte0001_5910 1.73e-46 164.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,41F1K@629|Yersinia 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJO1366.b4129,iWFL_1372.ECW_m4490 tRNA-synt_2,tRNA_anti-codon k141_10481_1 1278309.KB907099_gene3054 1.51e-82 262.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1XI7N@135619|Oceanospirillales 135619|Oceanospirillales I Acetyl propionyl-CoA carboxylase, alpha subunit - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 k141_13280_1 1216967.L100_14550 3.67e-21 90.5 arCOG06733@1|root,313GU@2|Bacteria,4NQIM@976|Bacteroidetes,1I3KE@117743|Flavobacteriia,34RMP@308865|Elizabethkingia 976|Bacteroidetes - - - - - - - - - - - - - - - k141_13280_2 1347392.CCEZ01000049_gene1527 0.000804 46.6 COG4978@1|root,COG4978@2|Bacteria,1V5CV@1239|Firmicutes,24HXP@186801|Clostridia,36J8S@31979|Clostridiaceae 186801|Clostridia KT GyrI-like small molecule binding domain - - - - - - - - - - - - GyrI-like k141_13280_4 1068978.AMETH_1005 1.95e-07 58.5 COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4DYFE@85010|Pseudonocardiales 201174|Actinobacteria I PFAM alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 k141_20946_1 491952.Mar181_0623 3.48e-88 280.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHCB@135619|Oceanospirillales 135619|Oceanospirillales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_736_2 395493.BegalDRAFT_3236 2.03e-40 140.0 COG2304@1|root,COG2304@2|Bacteria,1QVQA@1224|Proteobacteria,1S9W8@1236|Gammaproteobacteria,461GN@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 k141_736_3 1129794.C427_1893 1.09e-46 162.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,464NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA k141_13974_1 666685.R2APBS1_1177 1.24e-07 52.4 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1X61R@135614|Xanthomonadales 135614|Xanthomonadales J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k141_13974_2 1286106.MPL1_05519 1.68e-38 129.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,460WE@72273|Thiotrichales 72273|Thiotrichales J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 k141_14678_1 525897.Dbac_1341 3.64e-31 128.0 COG0845@1|root,COG2203@1|root,COG0845@2|Bacteria,COG2203@2|Bacteria,1N97Q@1224|Proteobacteria,42NAM@68525|delta/epsilon subdivisions,2WJTN@28221|Deltaproteobacteria,2MF14@213115|Desulfovibrionales 28221|Deltaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - GAF,HlyD_3,HlyD_D23 k141_17444_1 1134474.O59_004080 1.93e-88 283.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1FGCP@10|Cellvibrio 1236|Gammaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE - - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small k141_20255_1 472759.Nhal_0530 2.73e-18 85.9 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales 135613|Chromatiales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_20255_2 1286106.MPL1_11488 3.24e-57 183.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,460KS@72273|Thiotrichales 72273|Thiotrichales U MotA TolQ ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k141_12579_1 96561.Dole_0610 3.24e-11 70.9 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales 28221|Deltaproteobacteria K MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL k141_21633_1 1288826.MSNKSG1_06643 4.94e-144 431.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AM7@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2909 ATP-dependent transcriptional regulator malT - - ko:K03556 - - - - ko00000,ko03000 - - - GerE,TPR_19,TPR_4,TPR_8 k141_18860_1 713586.KB900536_gene2143 4.08e-58 202.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales 135613|Chromatiales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k141_9783_1 1123514.KB905899_gene853 5.91e-46 178.0 COG0642@1|root,COG2200@1|root,COG2200@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,NMT1,PAS,PAS_9,Response_reg k141_2816_1 1122137.AQXF01000001_gene3161 9.22e-98 316.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_13281_1 243090.RB7868 1.43e-39 141.0 COG1225@1|root,COG1225@2|Bacteria,2IZ7G@203682|Planctomycetes 203682|Planctomycetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,Redoxin k141_4204_1 1278309.KB907099_gene2794 1.45e-163 462.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XHPM@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_4204_2 1278309.KB907099_gene2795 1.47e-157 449.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XHI0@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_15369_1 1278309.KB907105_gene1533 2.79e-78 234.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XJI3@135619|Oceanospirillales 135619|Oceanospirillales K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins iscR - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 k141_15369_2 1278309.KB907105_gene1534 4.11e-273 749.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XHVJ@135619|Oceanospirillales 135619|Oceanospirillales E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k141_15369_4 1278309.KB907105_gene1536 4.72e-66 201.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1XK5J@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the HesB IscA family iscA - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn k141_15369_5 1278309.KB907105_gene1537 4.6e-94 278.0 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1XKE6@135619|Oceanospirillales 135619|Oceanospirillales O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB - - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C k141_15369_6 1278309.KB907105_gene1538 3.85e-134 397.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1XIID@135619|Oceanospirillales 135619|Oceanospirillales O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA - - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_16054_1 287.DR97_5225 5.73e-52 166.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1YG86@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K MerR family regulatory protein VL23_01195 - - - - - - - - - - - MerR_1 k141_1422_1 1278309.KB907106_gene1260 2.71e-150 449.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XHVX@135619|Oceanospirillales 135619|Oceanospirillales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_7012_1 1278309.KB907102_gene161 2.15e-40 140.0 COG0388@1|root,COG0388@2|Bacteria,1MXBR@1224|Proteobacteria,1RQ4Z@1236|Gammaproteobacteria,1XHKT@135619|Oceanospirillales 135619|Oceanospirillales S Carbon-nitrogen hydrolase - - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_7012_2 1278309.KB907102_gene160 8.93e-176 497.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XI0W@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase class I and II - - 2.6.1.84,2.6.1.88 ko:K12252,ko:K14287 ko00330,ko01100,map00330,map01100 - R08197,R08618 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_5606_1 696281.Desru_2671 1.74e-22 98.2 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_4 k141_5606_2 317025.Tcr_1221 1.66e-56 187.0 COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type phosphate phosphonate transport system periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd k141_11194_1 1288826.MSNKSG1_03732 3.6e-159 450.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,4650K@72275|Alteromonadaceae 1236|Gammaproteobacteria L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC k141_11194_2 1288826.MSNKSG1_03727 1.82e-235 671.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,4657J@72275|Alteromonadaceae 1236|Gammaproteobacteria CM COG1042 Acyl-CoA synthetase (NDP forming) yfiQ GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_10483_1 2340.JV46_04650 1.65e-09 60.5 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos k141_10483_2 472759.Nhal_1712 2.44e-19 86.7 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales 1236|Gammaproteobacteria F PFAM glycosyl transferase family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_738_1 1123514.KB905900_gene2067 1.42e-103 305.0 COG2850@1|root,COG2850@2|Bacteria,1RDTN@1224|Proteobacteria,1SDPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 k141_14679_1 391626.OAN307_c03800 3.15e-187 530.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve k141_20256_1 1232683.ADIMK_3234 3.46e-87 281.0 COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,4657J@72275|Alteromonadaceae 1236|Gammaproteobacteria CM COG1042 Acyl-CoA synthetase (NDP forming) yfiQ GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig k141_2817_2 743720.Psefu_3697 2.74e-69 224.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1YV49@136845|Pseudomonas putida group 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_11195_1 745014.OMB55_00004740 6.56e-43 153.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria 1236|Gammaproteobacteria U general secretion pathway protein xcsF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF k141_18148_1 1211579.PP4_31390 2.28e-67 219.0 COG0583@1|root,COG0583@2|Bacteria,1R1ZA@1224|Proteobacteria,1S379@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_18148_2 911045.PSE_2946 1.19e-127 373.0 COG1638@1|root,COG1638@2|Bacteria,1PER4@1224|Proteobacteria,2U0Q4@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP k141_25_1 994573.T472_0205120 1.76e-13 80.1 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes 1239|Firmicutes M domain protein - - - - - - - - - - - - DUF11 k141_9093_1 317025.Tcr_0442 4.68e-55 181.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,460E8@72273|Thiotrichales 72273|Thiotrichales J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_9093_2 1122164.JHWF01000001_gene1897 0.000258 42.7 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1JCM0@118969|Legionellales 118969|Legionellales I Biotin carboxylase C-terminal domain accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_6296_1 1049564.TevJSym_aa00880 1.43e-43 155.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1JC0J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_8409_1 909663.KI867150_gene1371 1.85e-23 102.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k141_2127_1 498211.CJA_0929 3.51e-06 50.4 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RS91@1236|Gammaproteobacteria,1FFTI@10|Cellvibrio 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k141_9109_1 43989.cce_2243 5.45e-73 253.0 COG5001@1|root,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,3KG35@43988|Cyanothece 1117|Cyanobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_18871_1 1121334.KB911067_gene189 6.39e-11 63.2 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae 186801|Clostridia J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_13300_1 380358.XALC_2190 1.66e-41 142.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CBS domain - - - - - - - - - - - - CBS k141_16774_1 2340.JV46_06000 1.99e-44 151.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1J6DD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C k141_17451_1 1278309.KB907101_gene422 0.0 947.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RMIU@1236|Gammaproteobacteria,1XHQR@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k141_17451_2 1278309.KB907101_gene423 2.57e-107 312.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,1XJX6@135619|Oceanospirillales 135619|Oceanospirillales S NnrU protein - - - - - - - - - - - - NnrU k141_17451_3 1278309.KB907101_gene424 6.72e-83 250.0 COG1802@1|root,COG1802@2|Bacteria,1Q85H@1224|Proteobacteria,1RZ0B@1236|Gammaproteobacteria,1XIUR@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K15735 - - - - ko00000,ko03000 - - - FCD,GntR k141_1435_2 1198232.CYCME_1559 1.44e-12 70.5 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,460ZS@72273|Thiotrichales 72273|Thiotrichales D Peptidase family M23 - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 k141_20266_1 317025.Tcr_1555 1.84e-144 412.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,460ZA@72273|Thiotrichales 72273|Thiotrichales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_4918_1 395493.BegalDRAFT_2465 1.46e-17 87.8 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales 72273|Thiotrichales O Peptidylprolyl isomerase - - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 k141_19028_1 653733.Selin_1727 3.52e-32 126.0 COG2206@1|root,COG2206@2|Bacteria 2|Bacteria T PFAM metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - DUF3391,HD,HD_5 k141_4378_2 393595.ABO_1032 6.85e-07 50.8 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1XHYX@135619|Oceanospirillales 135619|Oceanospirillales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA - 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k141_9215_1 1288826.MSNKSG1_16471 6.79e-106 307.0 COG3090@1|root,COG3090@2|Bacteria,1R4WJ@1224|Proteobacteria,1RZRQ@1236|Gammaproteobacteria,469X8@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k141_12042_1 1485545.JQLW01000010_gene1565 2.05e-17 82.4 COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - k141_21161_2 351348.Maqu_2513 2.67e-56 182.0 COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,1S1XJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 k141_3680_1 28229.ND2E_0534 2.62e-77 242.0 COG0842@1|root,COG0842@2|Bacteria,1QTBE@1224|Proteobacteria,1RNG9@1236|Gammaproteobacteria,2Q6FQ@267889|Colwelliaceae 1236|Gammaproteobacteria U ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 k141_15563_1 981384.AEYW01000013_gene512 3.17e-120 378.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,4NBWX@97050|Ruegeria 28211|Alphaproteobacteria EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_6447_1 1049564.TevJSym_am00160 8.81e-69 232.0 COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,1J9QI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N k141_170_1 1538295.JY96_08020 2.39e-34 133.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,1KJ0C@119065|unclassified Burkholderiales 28216|Betaproteobacteria D Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10,6.3.2.13 ko:K01929,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k141_21781_1 1250232.JQNJ01000001_gene812 1.6e-08 56.2 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase k141_21781_2 1124780.ANNU01000006_gene2875 7.22e-20 92.0 COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,47N37@768503|Cytophagia 976|Bacteroidetes I membrane - - - - - - - - - - - - - k141_16211_1 1122211.JMLW01000019_gene959 1.2e-20 94.4 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1XI63@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k141_16211_2 1260251.SPISAL_06435 8.83e-08 56.2 COG3147@1|root,COG3147@2|Bacteria,1MXHQ@1224|Proteobacteria,1RRKM@1236|Gammaproteobacteria,1WZKK@135613|Chromatiales 135613|Chromatiales D Sporulation related domain - - - ko:K03749 - - - - ko00000 - - - SPOR k141_10669_2 1288963.ADIS_3218 1.55e-58 188.0 COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,47MBX@768503|Cytophagia 976|Bacteroidetes O Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3,2OG-FeII_Oxy_4 k141_19706_1 1122137.AQXF01000003_gene2071 2.54e-62 209.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_11378_1 1156937.MFUM_870007 7.93e-36 138.0 COG0068@1|root,COG0068@2|Bacteria,46S89@74201|Verrucomicrobia,37FWV@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia O Acylphosphatase hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_20428_1 1124983.PFLCHA0_c50460 4.68e-52 175.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1YM7R@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase k141_19029_1 1123400.KB904747_gene552 5.39e-59 198.0 COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,1RQCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Radical SAM - - - - - - - - - - - - B12-binding,DUF4080,Radical_SAM k141_19029_2 1049564.TevJSym_ah00890 3.92e-45 150.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1J5QA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N k141_4379_1 522306.CAP2UW1_2225 8.41e-86 255.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria,1KQZR@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_4379_2 1219065.VPR01S_14_00030 1.87e-17 76.6 COG0346@1|root,COG0346@2|Bacteria,1N2SB@1224|Proteobacteria,1SA4P@1236|Gammaproteobacteria,1XY9F@135623|Vibrionales 135623|Vibrionales E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase k141_3681_1 1288826.MSNKSG1_04756 4.03e-120 349.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase k141_1581_2 1278309.KB907099_gene3116 5.78e-158 451.0 COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,1RMVA@1236|Gammaproteobacteria,1XHZC@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the adenine in position 1618 of 23S rRNA rlmF - 2.1.1.181 ko:K06970 - - R07232 RC00003,RC00335 ko00000,ko01000,ko03009 - - - Methyltransf_10 k141_1581_3 1278309.KB907099_gene3115 6.94e-92 272.0 2A8TA@1|root,30XW9@2|Bacteria,1RFF9@1224|Proteobacteria,1S42N@1236|Gammaproteobacteria,1XJYR@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_1581_4 1278309.KB907099_gene3114 3.53e-109 321.0 COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,1S4FU@1236|Gammaproteobacteria,1XRP3@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_9924_1 296591.Bpro_2495 1.67e-13 68.2 COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,2VT55@28216|Betaproteobacteria,4AEYR@80864|Comamonadaceae 28216|Betaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_9924_2 754477.Q7C_682 1.84e-26 107.0 COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria 1236|Gammaproteobacteria H molybdopterin-guanine dinucleotide biosynthesis protein mobB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.77 ko:K03753,ko:K13818 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - iB21_1397.B21_03691,iBWG_1329.BWG_3527,iECBD_1354.ECBD_4174,iECDH1ME8569_1439.ECDH1ME8569_3728,iEcDH1_1363.EcDH1_4130,iJO1366.b3856,iSbBS512_1146.SbBS512_E4328,iY75_1357.Y75_RS17805 MobB k141_7882_1 1038866.KB902770_gene4489 2.25e-05 47.0 COG1653@1|root,COG1653@2|Bacteria,1N1NW@1224|Proteobacteria,2U094@28211|Alphaproteobacteria,3K3GH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_7882_2 1370121.AUWS01000026_gene3200 3.57e-33 123.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N k141_3004_1 1049564.TevJSym_ao00250 8.87e-73 234.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1J4I7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_12767_1 1288826.MSNKSG1_14602 0.0 949.0 COG1807@1|root,COG1807@2|Bacteria,1MXH5@1224|Proteobacteria,1RSQE@1236|Gammaproteobacteria,464KM@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 k141_7166_1 1168067.JAGP01000001_gene2132 2.52e-88 270.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k141_4397_1 317025.Tcr_1150 2.6e-70 243.0 COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales 72273|Thiotrichales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9 k141_4397_2 1278309.KB907101_gene461 1.2e-169 476.0 COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,1RNF7@1236|Gammaproteobacteria,1XHWA@135619|Oceanospirillales 135619|Oceanospirillales V Transport permease protein - - - - - - - - - - - - ABC2_membrane k141_4397_3 1278309.KB907101_gene462 3.9e-132 380.0 COG1131@1|root,COG1131@2|Bacteria,1MX56@1224|Proteobacteria,1S0C7@1236|Gammaproteobacteria,1XIRY@135619|Oceanospirillales 135619|Oceanospirillales V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran k141_4397_4 1278309.KB907101_gene463 2.1e-66 216.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,1XHEM@135619|Oceanospirillales 135619|Oceanospirillales C Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,Lactonase k141_14863_1 1278309.KB907099_gene3134 3.15e-82 249.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria 1236|Gammaproteobacteria G protein conserved in bacteria - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF455 k141_14863_3 1278309.KB907099_gene3135 2.06e-190 533.0 2BXMY@1|root,2Z8Y9@2|Bacteria,1Q2YR@1224|Proteobacteria,1RR8Q@1236|Gammaproteobacteria,1XN9C@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14863_4 1278309.KB907099_gene3136 2.82e-91 269.0 COG0824@1|root,COG0824@2|Bacteria,1MZB3@1224|Proteobacteria,1SDTI@1236|Gammaproteobacteria,1XS9E@135619|Oceanospirillales 135619|Oceanospirillales S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 k141_14863_5 521719.ATXQ01000007_gene1166 7.06e-21 84.0 2DTA2@1|root,33JDB@2|Bacteria,1NI87@1224|Proteobacteria,1SH05@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Oxidoreductase-like protein, N-terminal - - - - - - - - - - - - Oxidored-like k141_14863_6 1278309.KB907099_gene3137 0.0 1378.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1XI3T@135619|Oceanospirillales 135619|Oceanospirillales C UPF0313 protein - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N k141_19047_1 472759.Nhal_2257 3.35e-97 288.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WWSW@135613|Chromatiales 135613|Chromatiales V PFAM ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_2265_1 765914.ThisiDRAFT_1870 1.07e-101 323.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales 135613|Chromatiales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k141_18320_1 1121948.AUAC01000003_gene2541 3.14e-05 45.1 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,43Y0B@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC k141_18320_2 1249997.JHZW01000003_gene2075 1.24e-63 210.0 COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia,2PH0T@252356|Maribacter 976|Bacteroidetes H MoeA N-terminal region (domain I and II) moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_6456_1 1177154.Y5S_00885 1.52e-93 282.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XI2H@135619|Oceanospirillales 135619|Oceanospirillales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA k141_4398_1 72664.XP_006404497.1 3.24e-49 158.0 COG0457@1|root,KOG1124@2759|Eukaryota,37TZH@33090|Viridiplantae,3GKZ9@35493|Streptophyta 35493|Streptophyta S Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits ycf3 - - - - - - - - - - - TPR_1 k141_21171_1 1287116.X734_08085 1.35e-22 103.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria,43NKB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U COG3210 Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - Glug,Haemagg_act k141_14864_1 1353537.TP2_01995 5.38e-78 244.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2XN47@285107|Thioclava 28211|Alphaproteobacteria C in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_14151_1 1041139.KB902578_gene5282 6.35e-69 221.0 COG1879@1|root,COG1879@2|Bacteria,1NZGQ@1224|Proteobacteria,2UDWV@28211|Alphaproteobacteria,4BD0A@82115|Rhizobiaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_4 k141_16933_2 395493.BegalDRAFT_2011 3.97e-70 223.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,4608J@72273|Thiotrichales 72273|Thiotrichales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like k141_19048_1 290398.Csal_2989 3.76e-49 172.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1XIAH@135619|Oceanospirillales 135619|Oceanospirillales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N k141_4399_1 675812.VHA_000584 1.79e-53 181.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XSRR@135623|Vibrionales 135623|Vibrionales S HI0933-like protein yhiN - - ko:K07007 - - - - ko00000 - - - HI0933_like k141_20454_2 713586.KB900536_gene2658 7.09e-90 276.0 COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1WZXR@135613|Chromatiales 135613|Chromatiales L COG1943 Transposase and inactivated derivatives - - - - - - - - - - - - - k141_16221_1 395493.BegalDRAFT_2995 1.23e-50 169.0 2A8YE@1|root,30Y24@2|Bacteria,1QBAG@1224|Proteobacteria,1T6V4@1236|Gammaproteobacteria,463E0@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k141_16221_3 1027273.GZ77_22155 1.3e-36 138.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XH7W@135619|Oceanospirillales 135619|Oceanospirillales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f k141_21804_1 90814.KL370891_gene1298 1.24e-18 81.3 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria 1224|Proteobacteria K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_21804_2 1049564.TevJSym_af00590 2.3e-23 93.2 COG1942@1|root,COG1942@2|Bacteria,1N1GC@1224|Proteobacteria,1SB41@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM macrophage migration inhibitory factor - - - - - - - - - - - - MIF k141_21172_1 626418.bglu_1g26140 9.97e-54 179.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1K1CS@119060|Burkholderiaceae 28216|Betaproteobacteria M glycosyl transferase group 1 gtrA - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k141_21172_2 1117315.AHCA01000002_gene3082 1.18e-27 108.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,2Q02U@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria HA62_17960 - - - - - - - - - - - Metallophos,Metallophos_2 k141_7167_1 472759.Nhal_3892 3.92e-129 399.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k141_181_1 1288826.MSNKSG1_12717 4.7e-121 347.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,466ZK@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins dsbA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k141_181_2 1288826.MSNKSG1_12722 1.77e-134 382.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,466NK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k141_181_3 1288826.MSNKSG1_12727 3.88e-145 409.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,466MM@72275|Alteromonadaceae 1236|Gammaproteobacteria D Necessary for normal cell division and for the maintenance of normal septation engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_181_4 1288826.MSNKSG1_12732 1.48e-147 416.0 COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,1S4A4@1236|Gammaproteobacteria,468EM@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR,TetR_N k141_181_5 1288826.MSNKSG1_12737 1.26e-178 507.0 COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,4656Y@72275|Alteromonadaceae 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family calB - 1.2.1.68 ko:K00154 - - - - ko00000,ko01000 - - - Aldedh k141_12066_1 1211579.PP4_07580 5.1e-20 97.8 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1YWW4@136845|Pseudomonas putida group 1236|Gammaproteobacteria U Belongs to the GSP D family rcpA - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - Secretin,T2SS-T3SS_pil_N k141_1598_1 329726.AM1_2488 9.72e-46 155.0 COG3001@1|root,COG3001@2|Bacteria,1G040@1117|Cyanobacteria 1117|Cyanobacteria G PFAM Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - - - - - - - - - - Fructosamin_kin k141_1598_2 1265313.HRUBRA_01471 2.21e-10 66.2 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1S4NJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Bacterial lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_16934_1 1278309.KB907099_gene3064 4.85e-150 430.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1XHD8@135619|Oceanospirillales 135619|Oceanospirillales I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_19049_1 396588.Tgr7_0981 2.52e-158 462.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_9925_1 765911.Thivi_3223 8.24e-77 252.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales 135613|Chromatiales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k141_9925_2 675817.VDA_002850 4.28e-46 158.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales 135623|Vibrionales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase k141_182_1 1121481.AUAS01000013_gene4296 2.33e-23 96.3 COG0115@1|root,COG0115@2|Bacteria,4NSFJ@976|Bacteroidetes,47PY5@768503|Cytophagia 976|Bacteroidetes EH Amino-transferase class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_182_2 1121481.AUAS01000013_gene4297 2.71e-45 155.0 COG0147@1|root,COG0147@2|Bacteria,4NFKB@976|Bacteroidetes,47N8A@768503|Cytophagia 976|Bacteroidetes EH chorismate binding enzyme pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Chorismate_bind k141_2266_1 1049564.TevJSym_ap00720 3.4e-293 831.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k141_7884_2 1120977.JHUX01000003_gene586 6.35e-32 112.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,3NPEH@468|Moraxellaceae 1236|Gammaproteobacteria S Fe-S assembly protein IscX iscX GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - - - - - - - - - - Fe-S_assembly k141_7884_3 870187.Thini_1264 2.37e-66 202.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Ferredoxin, 2Fe-2S type, ISC system fdx - - ko:K04755 - - - - ko00000 - - - Fer2 k141_7884_4 545264.KB898756_gene1598 3.48e-41 152.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1X01D@135613|Chromatiales 135613|Chromatiales O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA - - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k141_14865_1 743299.Acife_2600 2.03e-50 172.0 COG0446@1|root,COG0446@2|Bacteria,1QVWR@1224|Proteobacteria,1S0R6@1236|Gammaproteobacteria,2NBYY@225057|Acidithiobacillales 225057|Acidithiobacillales S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_14865_2 1122194.AUHU01000009_gene3247 8.51e-27 109.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,466K6@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_12067_1 413404.Rmag_0518 1.46e-18 84.7 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1J8P1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EH Anthranilate synthase component I, N terminal region pabB - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_12067_2 95619.PM1_0225735 5.98e-65 209.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH 4-amino-4-deoxychorismate lyase pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Aminotran_4 k141_18324_1 488538.SAR116_1471 5.92e-59 193.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 k141_20455_2 1392486.JIAF01000004_gene1417 4.93e-05 52.4 COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,2FP40@200643|Bacteroidia 976|Bacteroidetes S CAAX amino terminal protease family - - - ko:K07052 - - - - ko00000 - - - Abi k141_10685_1 1123368.AUIS01000002_gene1534 1.48e-302 868.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,2NBY2@225057|Acidithiobacillales 225057|Acidithiobacillales C Domain of unknown function (DUF3400) - - - - - - - - - - - - CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8 k141_17804_2 1278309.KB907108_gene1587 0.0 964.0 28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,1T4JE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11522_1 1387312.BAUS01000002_gene517 6.99e-33 125.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KKX0@206350|Nitrosomonadales 206350|Nitrosomonadales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_11522_2 1266914.ATUK01000002_gene487 3.06e-76 246.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_3192_3 1415778.JQMM01000001_gene1339 2.62e-07 55.5 2EJ60@1|root,2ZBZU@2|Bacteria,1RCGD@1224|Proteobacteria,1S2FZ@1236|Gammaproteobacteria,1J652@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Atypical PilZ domain, cyclic di-GMP receptor - - - - - - - - - - - - PilZ_2 k141_1059_1 522373.Smlt3825 3.13e-57 194.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1X3US@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k141_1059_2 1118235.CAJH01000022_gene1413 9.66e-17 81.3 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1X4XB@135614|Xanthomonadales 135614|Xanthomonadales NU assembly protein (PilN) pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN k141_16353_1 713586.KB900536_gene2669 3.88e-38 139.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria,1WZ2D@135613|Chromatiales 135613|Chromatiales S DUF218 domain - - - - - - - - - - - - DUF218 k141_5226_1 1123400.KB904783_gene1946 7.01e-07 50.4 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,460KB@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N k141_5226_2 1056820.KB900652_gene3292 1.46e-106 318.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,2PMV3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria F AIR synthase related protein, N-terminal domain purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2340 AIRS,AIRS_C k141_7330_1 1232437.KL661988_gene230 1.39e-11 69.7 2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,2MHXS@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_12929_1 768671.ThimaDRAFT_1370 2.31e-52 178.0 COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales 135613|Chromatiales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_12929_2 1121939.L861_21955 8.46e-33 122.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria,1XMCH@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09926 - - - - ko00000 - - - FixH k141_12929_3 1122197.ATWI01000009_gene1908 5.9e-24 103.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4650C@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0348 Polyferredoxin ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_13597_1 926550.CLDAP_14120 3.93e-50 185.0 COG3170@1|root,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - DUF1631 k141_10095_1 1288826.MSNKSG1_01098 7.45e-145 414.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,464XR@72275|Alteromonadaceae 1236|Gammaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) tas GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - - - - - - - - - - Aldo_ket_red k141_10095_3 1288826.MSNKSG1_01108 0.0 1430.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,46523@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0427 Acetyl-CoA hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C k141_10095_4 1288826.MSNKSG1_01113 2.71e-111 319.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1SPWN@1236|Gammaproteobacteria,46CRM@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 - - - - - - - - - - - - FKBP_C k141_12239_1 1249627.D779_2402 1.45e-220 617.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1WWT1@135613|Chromatiales 135613|Chromatiales O TIGRFAM FeS assembly protein SufB - - - ko:K09014 - - - - ko00000 - - - UPF0051 k141_379_1 86416.Clopa_1407 4e-15 79.7 COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,247IW@186801|Clostridia,36DYT@31979|Clostridiaceae 186801|Clostridia L DNA mismatch repair protein MutS mutS4 - - - - - - - - - - - MutS_III,MutS_V k141_8102_1 1278309.KB907102_gene160 5.44e-63 203.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XI0W@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase class I and II - - 2.6.1.84,2.6.1.88 ko:K12252,ko:K14287 ko00330,ko01100,map00330,map01100 - R08197,R08618 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k141_3193_1 1278309.KB907100_gene2100 4.21e-116 343.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1XH3F@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 k141_3193_2 1278309.KB907100_gene2099 3.14e-53 177.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1XIMG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the peptidase M20A family. ArgE subfamily argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k141_8714_1 95619.PM1_0228235 4.43e-34 125.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O oxidase, assembly ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 k141_8714_2 522373.Smlt0432 1.26e-45 157.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X3ZT@135614|Xanthomonadales 135614|Xanthomonadales C Heme copper-type cytochrome quinol oxidase subunit 3 cox3 - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_17805_1 1049564.TevJSym_ag01070 1.51e-118 353.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1J5T7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_11524_1 1386969.AWTB01000021_gene1420 4.18e-10 66.6 COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4GC61@85026|Gordoniaceae 201174|Actinobacteria L Helicase associated domain (HA2) Add an annotation hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_13598_2 713586.KB900536_gene929 0.000243 43.5 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales 135613|Chromatiales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k141_21988_1 1278309.KB907100_gene2178 4.2e-147 422.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XH9R@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase - - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_12930_2 395493.BegalDRAFT_3358 2.95e-47 166.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,460W5@72273|Thiotrichales 72273|Thiotrichales M PFAM Gram-negative bacterial tonB protein - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_10847_1 1278309.KB907110_gene3217 8.68e-219 618.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XHZZ@135619|Oceanospirillales 135619|Oceanospirillales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k141_10847_2 1278309.KB907110_gene3218 2e-273 754.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k141_14982_1 1163617.SCD_n02324 1.64e-11 63.5 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_14982_2 283166.BH06130 5.99e-64 205.0 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria,48TP7@772|Bartonellaceae 28211|Alphaproteobacteria C Nitroreductase family pnbA - - - - - - - - - - - Nitroreductase k141_14982_3 1249627.D779_0434 6.81e-70 214.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1WXYW@135613|Chromatiales 135613|Chromatiales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k141_4565_1 1288826.MSNKSG1_16286 4.12e-149 426.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,466MJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S secreted hydrolase attH - - - - - - - - - - - CrtC,Lipocalin_9 k141_4565_2 1479237.JMLY01000001_gene792 2.39e-144 410.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,466NX@72275|Alteromonadaceae 1236|Gammaproteobacteria O PFAM 20S proteasome, A and B subunits - - - ko:K07395 - - - - ko00000 - - - Proteasome k141_4565_3 1415754.JQMK01000002_gene2097 1.75e-82 250.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1RNV8@1236|Gammaproteobacteria,465M7@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1305 Transglutaminase-like enzymes - - - - - - - - - - - - Bact_transglu_N,Transglut_core k141_8103_1 1122599.AUGR01000002_gene3286 1.19e-26 106.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1XIX6@135619|Oceanospirillales 135619|Oceanospirillales E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ - - ko:K06203 - - - - ko00000 - - - EI24 k141_8103_2 396588.Tgr7_2028 7.32e-16 77.8 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1WW9A@135613|Chromatiales 135613|Chromatiales G PFAM carbohydrate kinase - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N k141_19231_3 1328313.DS2_01788 1.43e-21 87.8 2E8IW@1|root,332WU@2|Bacteria,1N6NY@1224|Proteobacteria,1SCX1@1236|Gammaproteobacteria,468TD@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1060_1 1288826.MSNKSG1_16871 1.46e-90 270.0 COG1346@1|root,COG1346@2|Bacteria,1R80J@1224|Proteobacteria,1S039@1236|Gammaproteobacteria,46DFX@72275|Alteromonadaceae 1236|Gammaproteobacteria M effector of murein hydrolase - - - - - - - - - - - - LrgB k141_1060_2 1288826.MSNKSG1_16876 1.62e-209 588.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,465MM@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0747 ABC-type dipeptide transport system, periplasmic component dppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_1778_1 1342299.Z947_4127 6.07e-120 346.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria,3ZVQ6@60136|Sulfitobacter 28211|Alphaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k141_1778_2 272943.RSP_1030 6.67e-89 270.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,1FAVI@1060|Rhodobacter 28211|Alphaproteobacteria H PFAM PfkB pfkB - 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k141_3194_1 324602.Caur_2618 8.04e-12 66.6 2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi,3778C@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function (DUF4395) - - - - - - - - - - - - DUF4395 k141_3194_2 1267534.KB906760_gene1494 2.73e-38 132.0 COG4994@1|root,COG4994@2|Bacteria,3Y8HQ@57723|Acidobacteria,2JNII@204432|Acidobacteriia 204432|Acidobacteriia S Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - DUF4440 k141_5229_1 666509.RCA23_c25920 9.75e-22 92.8 COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,2TRR5@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Precorrin-6y C5,15-methyltransferase cobL - 2.1.1.132 ko:K00595 ko00860,ko01100,map00860,map01100 - R05149 RC00003,RC01279 ko00000,ko00001,ko01000 - - - PCMT,TP_methylase k141_5229_2 314264.ROS217_13506 4.25e-91 273.0 COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,2TTJH@28211|Alphaproteobacteria,46P3F@74030|Roseovarius 28211|Alphaproteobacteria H COG2243 Precorrin-2 methylase cobI - 2.1.1.130,2.1.1.151 ko:K03394 ko00860,ko01100,map00860,map01100 - R03948,R05808 RC00003,RC01035,RC01662 ko00000,ko00001,ko01000 - - - TP_methylase k141_17806_1 697282.Mettu_1061 1.85e-158 484.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_12931_2 1500301.JQMF01000022_gene5681 4.14e-35 130.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria,4B7RA@82115|Rhizobiaceae 28211|Alphaproteobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr k141_1061_1 305900.GV64_02500 5.3e-53 170.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1XK2F@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_6607_1 1165096.ARWF01000001_gene1402 1.07e-09 62.8 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,2KKT6@206350|Nitrosomonadales 206350|Nitrosomonadales T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N k141_6607_2 1298593.TOL_3102 6.99e-43 146.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1XKFB@135619|Oceanospirillales 135619|Oceanospirillales G PTS fructose transporter subunit IIA ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 k141_6607_3 317025.Tcr_0972 1.05e-43 145.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,46133@72273|Thiotrichales 72273|Thiotrichales J Sigma 54 modulation protein yhbH - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k141_390_1 395493.BegalDRAFT_1894 8.84e-77 238.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,460JY@72273|Thiotrichales 72273|Thiotrichales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate - 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N k141_1082_2 686340.Metal_0210 1.79e-113 340.0 28I4Q@1|root,2Z886@2|Bacteria,1R41F@1224|Proteobacteria,1TI61@1236|Gammaproteobacteria,1XGKP@135618|Methylococcales 135618|Methylococcales S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 k141_1082_4 1123269.NX02_00150 8.08e-09 53.9 2EIDW@1|root,33C59@2|Bacteria,1NH9C@1224|Proteobacteria,2UKJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_1082_5 686340.Metal_0213 1.66e-44 168.0 2DBWF@1|root,2ZBGE@2|Bacteria,1N7XE@1224|Proteobacteria,1THYB@1236|Gammaproteobacteria,1XG17@135618|Methylococcales 135618|Methylococcales S Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotran_2 k141_1794_1 1278309.KB907107_gene1730 4.65e-134 415.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales 135619|Oceanospirillales T COG0591 Na proline symporter - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF k141_13625_1 754477.Q7C_1936 1.39e-45 152.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,4612G@72273|Thiotrichales 72273|Thiotrichales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_19242_1 1288826.MSNKSG1_06393 5.11e-173 483.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,467Q6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases yafS - - - - - - - - - - - Methyltransf_11 k141_19242_2 1288826.MSNKSG1_06388 1.04e-106 307.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,4676A@72275|Alteromonadaceae 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k141_19242_3 1288826.MSNKSG1_06383 6.33e-163 456.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,46491@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_H,RNase_T k141_19242_4 1288826.MSNKSG1_06378 0.0 1077.0 COG2198@1|root,COG2198@2|Bacteria,1QY43@1224|Proteobacteria,1S0ZB@1236|Gammaproteobacteria,4641V@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fimL - - - - - - - - - - - Hpt k141_19242_5 1288826.MSNKSG1_06373 1.45e-149 421.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,4675M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_19242_6 1288826.MSNKSG1_06368 5.59e-68 206.0 COG3255@1|root,COG3255@2|Bacteria,1N206@1224|Proteobacteria,1S8RI@1236|Gammaproteobacteria,4695T@72275|Alteromonadaceae 1236|Gammaproteobacteria I sterol carrier protein - - - - - - - - - - - - SCP2 k141_19242_7 1288826.MSNKSG1_06363 2.23e-222 617.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,464N3@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sohB GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N k141_19242_8 1288826.MSNKSG1_06358 3.26e-227 627.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,4640J@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases yhfP - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_19242_9 1288826.MSNKSG1_06353 2.1e-118 338.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria,46803@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF934 k141_19242_10 1288826.MSNKSG1_06348 9.81e-78 246.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,465NM@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0155 Sulfite reductase, beta subunit (hemoprotein) cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k141_7342_1 1288826.MSNKSG1_01678 8.5e-121 346.0 COG1266@1|root,COG1266@2|Bacteria,1R5RA@1224|Proteobacteria,1S0ZC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi k141_7342_2 1288826.MSNKSG1_01673 2.52e-202 560.0 COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,1RPGI@1236|Gammaproteobacteria,465M2@72275|Alteromonadaceae 1236|Gammaproteobacteria I enoyl-CoA hydratase isomerase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k141_7342_3 1288826.MSNKSG1_01668 6.6e-230 634.0 COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,1RR5K@1236|Gammaproteobacteria,46A5V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 k141_7342_4 1288826.MSNKSG1_01663 1.76e-71 215.0 COG2329@1|root,COG2329@2|Bacteria,1RJMH@1224|Proteobacteria,1SAYM@1236|Gammaproteobacteria,4687E@72275|Alteromonadaceae 1236|Gammaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_7342_5 1288826.MSNKSG1_01658 1.91e-136 420.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1T3BM@1236|Gammaproteobacteria,469XC@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631,EAL,GGDEF k141_2453_2 1288826.MSNKSG1_10348 5.75e-71 213.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1SA21@1236|Gammaproteobacteria,468QR@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K04755 - - - - ko00000 - - - Fer2 k141_2453_3 1288826.MSNKSG1_10353 3.77e-115 338.0 COG2207@1|root,COG2207@2|Bacteria,1R6AG@1224|Proteobacteria,1RXY3@1236|Gammaproteobacteria,469VC@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k141_10269_2 1237149.C900_01581 6.63e-68 215.0 COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia 976|Bacteroidetes O PFAM SPFH domain Band 7 family - - - - - - - - - - - - Band_7 k141_1922_1 1280953.HOC_07529 7.6e-54 182.0 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,43WJE@69657|Hyphomonadaceae 28211|Alphaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - 1.14.13.1 ko:K00480 ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220 - R00818,R05632,R06915,R06936,R06939 RC00389 ko00000,ko00001,ko01000 - - - FAD_binding_3 k141_3334_2 713586.KB900536_gene2054 9e-22 94.4 2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1WZCE@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4124) - - - - - - - - - - - - BiPBP_C,DUF4124 k141_3334_3 519989.ECTPHS_01379 7.52e-19 87.8 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 k141_15129_1 857087.Metme_3008 4.4e-27 112.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XDZ2@135618|Methylococcales 135618|Methylococcales P ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_5425_1 998674.ATTE01000001_gene600 3.17e-148 421.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,45ZPG@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k141_5425_2 1122207.MUS1_03750 3.58e-10 58.2 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XKE3@135619|Oceanospirillales 135619|Oceanospirillales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_17227_1 506534.Rhein_0865 2.4e-97 291.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1WX5G@135613|Chromatiales 135613|Chromatiales C PFAM NADH flavin oxidoreductase NADH oxidase - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k141_17227_2 1278309.KB907099_gene3003 2.66e-125 360.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,1XMGI@135619|Oceanospirillales 135619|Oceanospirillales H Nicotinamide mononucleotide transporter - - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter k141_6060_1 582744.Msip34_0601 6.85e-49 163.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,2KMHV@206350|Nitrosomonadales 206350|Nitrosomonadales S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 k141_12423_2 1280688.AUJB01000010_gene2766 1.16e-67 215.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - MetW,Methyltransf_11,Methyltransf_23 k141_14385_1 439497.RR11_1670 7.28e-20 82.4 2E4FG@1|root,32ZAN@2|Bacteria,1NCGS@1224|Proteobacteria,2UI2T@28211|Alphaproteobacteria,4NCSE@97050|Ruegeria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_19382_1 1502852.FG94_01974 2.21e-22 90.9 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,474FN@75682|Oxalobacteraceae 28216|Betaproteobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase k141_19382_2 1304883.KI912532_gene1960 1.44e-35 132.0 2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,2KYBI@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - k141_19382_3 1283300.ATXB01000002_gene3124 6.51e-71 230.0 COG2199@1|root,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,1S284@1236|Gammaproteobacteria,1XESE@135618|Methylococcales 135618|Methylococcales T TIGRFAM Diguanylate cyclase - - - - - - - - - - - - DUF484,GGDEF k141_6092_1 1278309.KB907099_gene2757 1.92e-13 67.0 COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,1SA2T@1236|Gammaproteobacteria,1XKVA@135619|Oceanospirillales 135619|Oceanospirillales O HupE / UreJ protein - - - ko:K03192 - - - - ko00000 - - - HupE_UreJ k141_6092_2 1278309.KB907099_gene2756 5.22e-113 327.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,1XIDZ@135619|Oceanospirillales 135619|Oceanospirillales KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW k141_4760_1 857087.Metme_0919 1.31e-30 124.0 2B14X@1|root,31TIS@2|Bacteria,1RM4A@1224|Proteobacteria,1THW5@1236|Gammaproteobacteria,1XFV8@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - k141_13128_1 477228.YO5_11205 9.77e-93 280.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RZH1@1236|Gammaproteobacteria,1Z07S@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C COG3258 Cytochrome c - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k141_20724_1 6412.HelroP173514 3.06e-13 68.9 COG0852@1|root,KOG1713@2759|Eukaryota,38BAK@33154|Opisthokonta,3B9TX@33208|Metazoa,3CTAV@33213|Bilateria 33208|Metazoa C NADH dehydrogenase (quinone) activity NDUFS3 GO:0001558,GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007568,GO:0008137,GO:0008150,GO:0008152,GO:0008340,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009966,GO:0009968,GO:0009987,GO:0010257,GO:0010259,GO:0010646,GO:0010648,GO:0010941,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016604,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0023051,GO:0023057,GO:0030308,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0040008,GO:0042773,GO:0042775,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0045926,GO:0046034,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048856,GO:0050136,GO:0050789,GO:0050794,GO:0051128,GO:0055086,GO:0055114,GO:0060548,GO:0065003,GO:0065007,GO:0070013,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0072593,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902531,GO:1902532,GO:1990204,GO:2001233,GO:2001234,GO:2001242,GO:2001243 1.6.5.3,1.6.99.3 ko:K03936 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1.6 - - Complex1_30kDa k141_20724_2 70448.Q0P3H6 3.11e-75 236.0 COG0649@1|root,KOG2870@2759|Eukaryota,37S7T@33090|Viridiplantae,34JA3@3041|Chlorophyta 3041|Chlorophyta C Belongs to the complex I 49 kDa subunit family - - 1.6.5.3,1.6.99.3 ko:K03935 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1.6 - - Complex1_49kDa k141_22145_1 225937.HP15_2397 3.43e-197 560.0 COG0667@1|root,COG1861@1|root,COG0667@2|Bacteria,COG1861@2|Bacteria,1RC4U@1224|Proteobacteria,1S6AT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red,CTP_transf_3 k141_22145_2 1122951.ATUE01000005_gene1677 5.78e-96 289.0 COG1028@1|root,COG1028@2|Bacteria,1ND2U@1224|Proteobacteria,1RZZH@1236|Gammaproteobacteria,3NMAA@468|Moraxellaceae 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_22145_3 225937.HP15_2395 5.83e-09 55.8 COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,1RYTC@1236|Gammaproteobacteria,4675D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Spore coat polysaccharide biosynthesis protein - - - - - - - - - - - - Acetyltransf_3,Glyco_tran_28_C k141_17251_1 743720.Psefu_3384 1.06e-08 55.5 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1YXDQ@136845|Pseudomonas putida group 1236|Gammaproteobacteria IQ PFAM AMP-dependent synthetase and ligase alkK - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_17251_2 876044.IMCC3088_662 1.68e-116 347.0 COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria,1J7KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EG COG2610 H gluconate symporter and related permeases - - - - - - - - - - - - GntP_permease k141_14410_1 1049564.TevJSym_av00430 1.02e-57 193.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1J4CI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM k141_14410_2 909663.KI867149_gene3210 2.68e-11 61.2 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,43ACP@68525|delta/epsilon subdivisions,2WW7Y@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k141_2604_1 765913.ThidrDRAFT_0025 2.7e-60 213.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - - - - - - - - - - CheW,HATPase_c,Hpt,Response_reg k141_18015_1 1123261.AXDW01000007_gene2198 5.01e-31 119.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1X3Y4@135614|Xanthomonadales 135614|Xanthomonadales NU twitching motility protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k141_18015_2 1336233.JAEH01000001_gene722 7.61e-18 86.3 COG0642@1|root,COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1R4W2@1224|Proteobacteria,1RYS1@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator receiver - - - ko:K07814 - - - - ko00000,ko02022 - - - HATPase_c,HD_5,HisKA,Response_reg k141_11678_1 1168067.JAGP01000001_gene163 1.52e-72 227.0 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1S4AM@1236|Gammaproteobacteria,461EF@72273|Thiotrichales 72273|Thiotrichales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_21484_1 572480.Arnit_2877 7.15e-11 63.2 COG3334@1|root,COG3334@2|Bacteria 2|Bacteria S PFAM MgtE intracellular ylxF - - ko:K02383 - - - - ko00000,ko02035 - - - MgtE_N k141_15893_1 1121459.AQXE01000001_gene2749 3.43e-28 116.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k141_3352_1 1278309.KB907101_gene543 2.43e-130 381.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XH5E@135619|Oceanospirillales 135619|Oceanospirillales C 2-oxoglutarate dehydrogenase complex lpdG - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_3352_3 1278309.KB907101_gene545 4.16e-200 555.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1XH3G@135619|Oceanospirillales 135619|Oceanospirillales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA k141_551_1 382464.ABSI01000023_gene590 1.57e-19 82.4 COG1017@1|root,COG1017@2|Bacteria,46TTM@74201|Verrucomicrobia,2IVC4@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Globin - - - - - - - - - - - - FAD_binding_6,Globin,NAD_binding_1 k141_551_3 1168065.DOK_09696 9.65e-41 146.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1J59G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_13129_1 95619.PM1_0209710 5.09e-79 244.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 k141_13820_1 270374.MELB17_10488 4.46e-11 58.9 2ECSP@1|root,336Q8@2|Bacteria,1NAR1@1224|Proteobacteria,1SG58@1236|Gammaproteobacteria,46C4M@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13820_2 1122599.AUGR01000005_gene1773 2.01e-18 77.4 2EQAZ@1|root,33HX4@2|Bacteria,1NGHQ@1224|Proteobacteria,1SH13@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - IV02_08010 - - - - - - - - - - - - k141_13820_3 1410620.SHLA_2c002170 2.17e-226 633.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,4BEYC@82115|Rhizobiaceae 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM k141_13820_4 467661.RKLH11_3714 1.72e-30 114.0 COG3090@1|root,COG3090@2|Bacteria,1R4WJ@1224|Proteobacteria,2U2ZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system small permease component uehB - - - - - - - - - - - DctQ k141_6735_2 1243664.CAVL020000008_gene4242 1.82e-31 116.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis dfrA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k141_2605_1 318586.Pden_1223 1.45e-46 162.0 COG0582@1|root,COG0582@2|Bacteria,1R6DN@1224|Proteobacteria,2TUXI@28211|Alphaproteobacteria,2PXYD@265|Paracoccus 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k141_18016_1 1500897.JQNA01000002_gene2909 1.48e-27 117.0 COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria,2VKYZ@28216|Betaproteobacteria,1K0Y2@119060|Burkholderiaceae 28216|Betaproteobacteria T histidine kinase HAMP region domain protein - - - - - - - - - - - - GGDEF,HAMP,dCache_1 k141_3353_1 1123400.KB904769_gene2881 2.82e-13 76.6 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,45ZMZ@72273|Thiotrichales 72273|Thiotrichales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k141_14411_2 1366050.N234_10995 1.74e-77 243.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,1K1VT@119060|Burkholderiaceae 28216|Betaproteobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase k141_20001_1 714961.BFZC1_15815 3.27e-08 52.0 COG2329@1|root,COG2329@2|Bacteria,1VAM1@1239|Firmicutes,4HJD7@91061|Bacilli,3IYMK@400634|Lysinibacillus 91061|Bacilli S Antibiotic biosynthesis monooxygenase yqjZ - - - - - - - - - - - ABM k141_20001_2 1202962.KB907150_gene1929 1.15e-24 102.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ybaP - - ko:K09973 - - - - ko00000 - - - TraB k141_17252_1 555778.Hneap_1706 7.26e-39 131.0 COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,1SAV8@1236|Gammaproteobacteria,1WZPV@135613|Chromatiales 135613|Chromatiales S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP k141_21485_1 1121935.AQXX01000086_gene5243 5.79e-16 78.2 COG0664@1|root,COG0664@2|Bacteria,1RKRH@1224|Proteobacteria,1S42Z@1236|Gammaproteobacteria,1XRTX@135619|Oceanospirillales 135619|Oceanospirillales T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding k141_22146_1 1178482.BJB45_20105 2e-41 140.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1XJKM@135619|Oceanospirillales 135619|Oceanospirillales J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_22146_2 765910.MARPU_16585 1.58e-105 316.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1WXMZ@135613|Chromatiales 135613|Chromatiales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_18662_2 1211777.BN77_p2140034 3.15e-06 55.5 COG2197@1|root,COG2197@2|Bacteria,1RM5G@1224|Proteobacteria,2UAKQ@28211|Alphaproteobacteria,4BFBG@82115|Rhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_18662_3 1278309.KB907100_gene2121 4.32e-200 565.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1XJEF@135619|Oceanospirillales 135619|Oceanospirillales S ErfK YbiS YcfS YnhG family protein - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD k141_18662_4 1278309.KB907100_gene2120 6.58e-83 249.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,1XKC0@135619|Oceanospirillales 135619|Oceanospirillales S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_2 k141_552_1 1278309.KB907101_gene744 2.22e-121 368.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1XI15@135619|Oceanospirillales 135619|Oceanospirillales S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 k141_13821_1 105559.Nwat_0486 1.37e-52 175.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_13821_2 1218075.BAYA01000004_gene1231 1.24e-19 83.2 COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,1K9EN@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the UPF0250 family ybeD - - ko:K09158 - - - - ko00000 - - - DUF493 k141_13821_3 1123279.ATUS01000006_gene3528 7.71e-40 138.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1J5SC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB k141_3354_2 1123393.KB891316_gene1129 1.61e-57 184.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales 119069|Hydrogenophilales S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI k141_4761_3 195522.BD01_0263 1.29e-24 104.0 COG4902@1|root,arCOG03957@2157|Archaea,2Y2Y5@28890|Euryarchaeota,245FE@183968|Thermococci 183968|Thermococci S Uncharacterized protein domain (DUF2202) - - - - - - - - - - - - DUF2202 k141_5448_1 1208323.B30_16958 2.15e-07 50.8 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2TQWY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM NnrUfamily protein nnrU - - - - - - - - - - - NnrU k141_5448_2 1510531.JQJJ01000010_gene2604 1.12e-24 94.0 COG5515@1|root,COG5515@2|Bacteria,1N87I@1224|Proteobacteria,2UF35@28211|Alphaproteobacteria 28211|Alphaproteobacteria S conserved small protein - - - - - - - - - - - - DUF1737 k141_22147_1 713586.KB900536_gene284 2.55e-47 163.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1WW8H@135613|Chromatiales 135613|Chromatiales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k141_18017_1 1500894.JQNN01000001_gene2947 3.97e-28 110.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,473WN@75682|Oxalobacteraceae 28216|Betaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_20002_1 1198232.CYCME_1104 3.91e-26 102.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,460JJ@72273|Thiotrichales 72273|Thiotrichales F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin k141_20002_2 265072.Mfla_1501 8.37e-42 147.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,2KKWE@206350|Nitrosomonadales 206350|Nitrosomonadales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG k141_8844_1 1122947.FR7_1605 2.24e-119 350.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4H3K3@909932|Negativicutes 909932|Negativicutes M NAD(P)H-binding - - - - - - - - - - - - GDP_Man_Dehyd k141_8844_2 1144319.PMI16_04692 2.66e-107 322.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,476D1@75682|Oxalobacteraceae 28216|Betaproteobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - Acetyltransf_3,CBS,DegT_DnrJ_EryC1 k141_14412_1 756499.Desde_3495 2.17e-39 143.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,2629Q@186807|Peptococcaceae 186801|Clostridia M PFAM Transglycosylase SLT domain yjbJ - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT k141_3355_1 1123393.KB891331_gene2846 4.28e-36 132.0 COG3221@1|root,COG3221@2|Bacteria,1PHN6@1224|Proteobacteria,2W8YN@28216|Betaproteobacteria,1KTGS@119069|Hydrogenophilales 119069|Hydrogenophilales P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - - - - - - - - - - Phosphonate-bd k141_16549_1 491952.Mar181_3510 5.43e-224 627.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XHN7@135619|Oceanospirillales 135619|Oceanospirillales S Tripartite tricarboxylate transporter TctA - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA k141_16549_2 400668.Mmwyl1_4434 9.82e-66 203.0 2DP8D@1|root,33103@2|Bacteria,1N80N@1224|Proteobacteria,1S6UN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB k141_16549_3 1232683.ADIMK_2577 1.61e-175 496.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,1RPKH@1236|Gammaproteobacteria,46ADN@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter family receptor tctC - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC k141_16549_4 400668.Mmwyl1_4432 2.82e-111 325.0 COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,1RYIX@1236|Gammaproteobacteria,1XNG0@135619|Oceanospirillales 135619|Oceanospirillales T transcriptional regulator - - - ko:K07666,ko:K07774 ko02020,ko02024,map02020,map02024 M00453,M00457 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_16549_5 491952.Mar181_3506 2.11e-142 422.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1T1KQ@1236|Gammaproteobacteria,1XN2T@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - 2.7.13.3 ko:K07649 ko02020,map02020 M00457 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k141_16549_6 491952.Mar181_3505 5.83e-116 347.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,1RMBC@1236|Gammaproteobacteria,1XP62@135619|Oceanospirillales 135619|Oceanospirillales P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_8 k141_16549_7 491952.Mar181_2541 1.13e-20 84.0 2ETFE@1|root,33KZC@2|Bacteria,1NQF2@1224|Proteobacteria,1SIZ1@1236|Gammaproteobacteria,1XMTF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_16549_8 1278309.KB907108_gene1586 2.32e-38 138.0 2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria,1XNQZ@135619|Oceanospirillales 135619|Oceanospirillales S Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - DUF1329 k141_9706_2 349124.Hhal_2085 1.98e-32 124.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales 135613|Chromatiales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_15273_2 1121918.ARWE01000001_gene2992 5.56e-24 103.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,43S51@69541|Desulfuromonadales 28221|Deltaproteobacteria M Mechanosensitive ion channel mscS-2 - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - MS_channel k141_14635_1 1278309.KB907101_gene485 9.61e-189 534.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIC9@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes - - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k141_14635_2 1123368.AUIS01000009_gene2472 5.51e-23 90.9 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria 1224|Proteobacteria NT Methyl-accepting chemotaxis protein - - - ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - PAS_3 k141_6877_1 207954.MED92_11194 1.21e-175 494.0 COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XI4S@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_6877_2 998674.ATTE01000001_gene212 4.44e-51 163.0 COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1T189@1236|Gammaproteobacteria,463TY@72273|Thiotrichales 72273|Thiotrichales S Putative heavy-metal-binding - - - - - - - - - - - - YbjQ_1 k141_6877_3 102125.Xen7305DRAFT_00032260 9.55e-05 43.9 COG0393@1|root,COG0393@2|Bacteria,1G74I@1117|Cyanobacteria,3VJVA@52604|Pleurocapsales 1117|Cyanobacteria S Putative heavy-metal-binding - - - - - - - - - - - - YbjQ_1 k141_20119_1 644107.SL1157_1548 1.39e-111 353.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,4NAWA@97050|Ruegeria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_4090_1 1198232.CYCME_0904 5.01e-79 252.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,460CG@72273|Thiotrichales 72273|Thiotrichales M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_11798_1 1042375.AFPL01000046_gene2020 4.34e-07 50.1 COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,467XB@72275|Alteromonadaceae 1236|Gammaproteobacteria S hydrolase (HAD superfamily) yigB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 ko:K20862 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 k141_11798_2 1278309.KB907100_gene2075 1.42e-178 503.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1XIGP@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k141_11798_3 1278309.KB907100_gene2076 9.94e-137 390.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1XJFR@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09921 - - - - ko00000 - - - DUF484 k141_11798_4 1278309.KB907100_gene2077 5.95e-58 186.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XHA1@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase k141_6880_1 1517416.IDAT_12655 6.03e-60 186.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,2QG2A@267893|Idiomarinaceae 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnB GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_6880_2 377629.TERTU_1053 1.71e-17 82.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,2PNAB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H NAD synthase nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase k141_9708_1 388401.RB2150_05733 2.87e-63 199.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,3ZGD0@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k141_6881_1 1318628.MARLIPOL_16214 2.88e-50 182.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,464FF@72275|Alteromonadaceae 1236|Gammaproteobacteria O Belongs to the peptidase S16 family - - - ko:K04770 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k141_15278_1 83406.HDN1F_33730 7.76e-19 91.7 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1J5AR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_6882_1 1283300.ATXB01000002_gene3021 2.85e-21 94.7 COG0810@1|root,COG0810@2|Bacteria,1QXPZ@1224|Proteobacteria,1T3FQ@1236|Gammaproteobacteria,1XH0Z@135618|Methylococcales 135618|Methylococcales M TolA C-terminal - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k141_6882_2 472759.Nhal_0183 1.67e-19 89.4 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales 135613|Chromatiales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_20121_1 1288826.MSNKSG1_08498 4.31e-312 851.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,4653T@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadI - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_11801_1 314270.RB2083_3811 5.42e-44 161.0 COG1566@1|root,COG1566@2|Bacteria,1QVP6@1224|Proteobacteria,2TWJ2@28211|Alphaproteobacteria,3ZG4Q@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria V Multidrug resistance efflux pump - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_15279_1 1163408.UU9_13758 9.7e-91 285.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1X55W@135614|Xanthomonadales 135614|Xanthomonadales E Peptidase family M3 prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_4091_1 1288826.MSNKSG1_06533 1.66e-246 678.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,465TC@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082 Iso_dh k141_4091_2 1288826.MSNKSG1_06528 9.62e-269 735.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,465AH@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k141_11802_1 519989.ECTPHS_10381 1.34e-163 470.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k141_6884_1 1278309.KB907103_gene1153 7.39e-311 868.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the aconitase IPM isomerase family acnB - 4.2.1.3,4.2.1.99 ko:K01682 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173 R01324,R01325,R01900,R04425 RC00497,RC00498,RC00618,RC01153 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_2_N,Aconitase_B_N k141_20124_1 870187.Thini_1858 6.2e-51 182.0 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales 72273|Thiotrichales S Belongs to the UPF0753 family - - - - - - - - - - - - DUF2309 k141_9709_1 396588.Tgr7_2033 3.24e-77 251.0 COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1WWHM@135613|Chromatiales 135613|Chromatiales Q TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM,DctQ k141_9709_2 349521.HCH_01653 3.01e-280 790.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_4093_2 1121934.AUDX01000007_gene1803 3.52e-05 49.3 COG2207@1|root,COG2207@2|Bacteria,2GITD@201174|Actinobacteria,4FRTB@85023|Microbacteriaceae 201174|Actinobacteria K AraC-binding-like domain - - - - - - - - - - - - AraC_binding_2,HTH_18 k141_6886_1 1122603.ATVI01000007_gene1746 1.6e-13 69.7 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1X4CA@135614|Xanthomonadales 135614|Xanthomonadales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k141_6886_2 1201293.AKXQ01000003_gene2591 3.31e-66 217.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Flagellar rod assembly protein muramidase FlgJ flgJ GO:0003674,GO:0005198 - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k141_20125_2 1205680.CAKO01000009_gene4041 1.4e-80 250.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales 204441|Rhodospirillales S MazG nucleotide pyrophosphohydrolase domain mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG k141_9711_1 1116472.MGMO_145c00050 9.28e-154 447.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XEM6@135618|Methylococcales 135618|Methylococcales F Thymidine phosphorylase - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C k141_11806_1 1055815.AYYA01000057_gene262 2.38e-08 55.5 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,3NINK@468|Moraxellaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_11806_2 314345.SPV1_05003 4.42e-53 176.0 COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria 1224|Proteobacteria O Protein-disulfide isomerase VP2116 - - ko:K07396 - - - - ko00000 - - - DSBA,Thioredoxin_5 k141_6887_1 1095769.CAHF01000022_gene432 2.55e-71 249.0 COG3209@1|root,COG3209@2|Bacteria,1QJCC@1224|Proteobacteria,2WF53@28216|Betaproteobacteria 28216|Betaproteobacteria M COG3209 Rhs family protein - - - ko:K11021 - - - - ko00000,ko02042 - - - SpvB,TcdB_toxin_midC,TcdB_toxin_midN k141_6888_1 1238182.C882_3485 2.06e-33 130.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JVCZ@204441|Rhodospirillales 204441|Rhodospirillales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_5594_4 1288826.MSNKSG1_05381 4.43e-127 367.0 COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,1RMQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria P thiamine ABC transporter tbpA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015888,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0030975,GO:0030976,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0045117,GO:0048037,GO:0050662,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0071702,GO:0071705,GO:0072348,GO:0097159,GO:1901363,GO:1901681 - ko:K02064 ko02010,map02010 M00191 - - ko00000,ko00001,ko00002,ko02000 3.A.1.19 - iAPECO1_1312.APECO1_1914,iSFxv_1172.SFxv_0065,iUTI89_1310.UTI89_C0076 SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8 k141_3501_1 1121918.ARWE01000001_gene3561 2.09e-72 226.0 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,42RTY@68525|delta/epsilon subdivisions,2WNFS@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_6988_1 1280944.HY17_12510 3.94e-29 115.0 2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,2UIVA@28211|Alphaproteobacteria,43YCR@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_720_1 90813.JQMT01000001_gene702 1.26e-83 267.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,461PI@72273|Thiotrichales 72273|Thiotrichales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - - - - - - - - - - - Proton_antipo_M,Proton_antipo_N k141_12569_1 987059.RBXJA2T_14051 6.25e-60 194.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VMPX@28216|Betaproteobacteria,1KIXZ@119065|unclassified Burkholderiales 28216|Betaproteobacteria H Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR1 - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_15_2 1337093.MBE-LCI_3314 9.95e-71 228.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC transporter - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran k141_20931_1 1288826.MSNKSG1_11453 7.51e-151 426.0 COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,1S58J@1236|Gammaproteobacteria,46AZ5@72275|Alteromonadaceae 1236|Gammaproteobacteria D Cobyrinic acid a,c-diamide synthase - - - - - - - - - - - - AAA_31 k141_20931_3 1288826.MSNKSG1_11463 1.34e-143 414.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,464E9@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_5595_1 1255043.TVNIR_1599 8.98e-71 225.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_9773_1 314345.SPV1_08456 3e-191 551.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria 1224|Proteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - - - - - - - - - - XFP,XFP_N k141_14662_1 1504981.KO116_4720 1.48e-130 387.0 COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,1RR6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the amidase family - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_14662_2 1042375.AFPL01000029_gene3378 4.87e-216 603.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,1RMG8@1236|Gammaproteobacteria,469Q8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - 1.14.13.235 ko:K22027 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_2,Acyl-CoA_dh_N k141_14662_3 1121940.AUDZ01000017_gene2490 7.62e-63 194.0 2CFH0@1|root,32S2Y@2|Bacteria,1N1H9@1224|Proteobacteria,1S5FU@1236|Gammaproteobacteria,1XPWJ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_14662_4 1121374.KB891592_gene2889 5.03e-67 209.0 2ASE4@1|root,31HTP@2|Bacteria,1RHGP@1224|Proteobacteria,1S6BD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 k141_14662_5 493475.GARC_1717 2.98e-252 698.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RSEF@1236|Gammaproteobacteria,46AGC@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ring hydroxylating alpha subunit (catalytic domain) antA - 1.14.13.172 ko:K18242 ko00626,ko01120,map00626,map01120 M00638 R07709,R07710 RC00490 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k141_14662_6 634452.APA01_22040 3.48e-22 91.3 COG5517@1|root,COG5517@2|Bacteria,1RH37@1224|Proteobacteria,2UCU1@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Ring hydroxylating beta subunit - - - - - - - - - - - - Ring_hydroxyl_B k141_15357_1 1123368.AUIS01000003_gene1721 5.92e-23 97.1 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,2NCH7@225057|Acidithiobacillales 225057|Acidithiobacillales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 k141_15357_2 1049564.TevJSym_aa00800 2.17e-26 108.0 COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,1J6DZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:0090499,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - iBWG_1329.BWG_3103,iECBD_1354.ECBD_0333,iECDH10B_1368.ECDH10B_3587,iECDH1ME8569_1439.ECDH1ME8569_3291,iETEC_1333.ETEC_3662,iEcDH1_1363.EcDH1_0301,iJO1366.b3412,iY75_1357.Y75_RS20155 Abhydrolase_1,Abhydrolase_6 k141_11176_1 1288826.MSNKSG1_14842 2.83e-217 605.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,465H4@72275|Alteromonadaceae 1236|Gammaproteobacteria LU Rossmann fold nucleotide-binding protein involved in DNA uptake smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_12570_1 1200792.AKYF01000020_gene5159 7.84e-06 47.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,26SM7@186822|Paenibacillaceae 91061|Bacilli E Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k141_12570_2 1227739.Hsw_1484 1.34e-12 67.8 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia 976|Bacteroidetes C Dehydrogenase E1 component pdhB - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C k141_7692_1 1038860.AXAP01000037_gene3196 4.25e-27 117.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JX8Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Guanylate_cyc,TPR_2,Trans_reg_C k141_16751_1 768066.HELO_2035 1.86e-71 228.0 COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,1RWXS@1236|Gammaproteobacteria,1XIMB@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_13960_1 1288826.MSNKSG1_05833 5.07e-77 236.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria,46682@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k141_13960_2 1288826.MSNKSG1_05681 6.42e-101 308.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4650M@72275|Alteromonadaceae 1236|Gammaproteobacteria S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 k141_6989_1 1288826.MSNKSG1_10708 7.25e-28 108.0 COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,1RTQR@1236|Gammaproteobacteria,4663V@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_6989_2 1288826.MSNKSG1_10713 8.1e-128 383.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,465C8@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_14663_1 582744.Msip34_1722 3.43e-73 242.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,2KKCC@206350|Nitrosomonadales 206350|Nitrosomonadales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k141_9076_1 697282.Mettu_0391 5.66e-132 386.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,1T05M@1236|Gammaproteobacteria,1XG6W@135618|Methylococcales 135618|Methylococcales P Mediates influx of magnesium ions - - - - - - - - - - - - CorA k141_20932_1 1454004.AW11_01265 2.43e-61 203.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2VPFR@28216|Betaproteobacteria 28216|Betaproteobacteria P Citrate transporter - - - - - - - - - - - - CitMHS k141_4197_1 580332.Slit_1721 9.41e-57 180.0 2EJVG@1|root,318S5@2|Bacteria,1Q0VB@1224|Proteobacteria,2W5S9@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4279) - - - - - - - - - - - - DUF4279 k141_18842_1 1198232.CYCME_1912 4.06e-178 506.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,460BZ@72273|Thiotrichales 72273|Thiotrichales C D-isomer specific 2-hydroxyacid dehydrogenase serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C k141_8385_1 754476.Q7A_2823 3.82e-89 273.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales 72273|Thiotrichales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt k141_8385_2 318167.Sfri_0020 2.76e-158 463.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,2Q9NH@267890|Shewanellaceae 1236|Gammaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_11872_1 1122599.AUGR01000023_gene4136 4.32e-36 129.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XHGB@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_11872_2 1286106.MPL1_09887 1.75e-46 161.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,4614Z@72273|Thiotrichales 72273|Thiotrichales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k141_11872_3 944562.HMPREF9102_0518 1.15e-39 144.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k141_721_1 697282.Mettu_1061 5.88e-197 590.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales 135618|Methylococcales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k141_838_2 1122599.AUGR01000014_gene649 0.0 889.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHA0@135619|Oceanospirillales 135619|Oceanospirillales T Integral membrane sensor signal transduction histidine kinase - - 2.7.13.3 ko:K08475,ko:K10125 ko02020,map02020 M00503,M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k141_838_3 1278309.KB907100_gene2195 1.2e-185 523.0 COG1638@1|root,COG1638@2|Bacteria,1MUBS@1224|Proteobacteria,1RRBQ@1236|Gammaproteobacteria,1XHP2@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_9871_1 1122599.AUGR01000013_gene716 1.58e-30 125.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XI12@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k141_10606_1 1123247.AUIJ01000008_gene2593 5.77e-101 317.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2TU7G@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_15510_1 362418.IW19_03425 6.21e-25 104.0 COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,2NUW9@237|Flavobacterium 976|Bacteroidetes V Multidrug ABC transporter ATPase - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran k141_15510_2 686340.Metal_0980 4.96e-52 176.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XETF@135618|Methylococcales 135618|Methylococcales F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK k141_3629_1 713586.KB900536_gene1203 3.97e-197 575.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales 135613|Chromatiales T Belongs to the PEP-utilizing enzyme family - - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_3629_2 519989.ECTPHS_02354 1.16e-76 233.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales 135613|Chromatiales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_14082_1 1286106.MPL1_00722 9.46e-75 253.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales 72273|Thiotrichales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k141_4987_2 331869.BAL199_21774 2.25e-30 112.0 COG2246@1|root,COG2246@2|Bacteria,1N6ST@1224|Proteobacteria,2UCW9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM GtrA family protein - - - - - - - - - - - - GtrA k141_11346_1 754477.Q7C_1141 3.54e-31 122.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales 72273|Thiotrichales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_11346_2 425104.Ssed_2580 2.51e-17 77.0 COG2105@1|root,COG2105@2|Bacteria,1PJ0B@1224|Proteobacteria,1TJSA@1236|Gammaproteobacteria,2QE62@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM AIG2 family protein - - - - - - - - - - - - - k141_3648_1 1231190.NA8A_05953 5.2e-19 86.3 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2U3PI@28211|Alphaproteobacteria,43P41@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_12700_1 232721.Ajs_2740 1.5e-12 63.5 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2VUB7@28216|Betaproteobacteria,4AF35@80864|Comamonadaceae 28216|Betaproteobacteria P Belongs to the ArsC family yffB - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC k141_14112_1 1288826.MSNKSG1_04701 2.07e-77 236.0 COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,46451@72275|Alteromonadaceae 1236|Gammaproteobacteria DT COG1718 Serine threonine protein kinase involved in cell cycle control IV02_22125 - 2.7.11.1 ko:K07178 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko01001,ko03009 - - - RIO1 k141_14112_2 1288826.MSNKSG1_04696 4.95e-88 263.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria,465HQ@72275|Alteromonadaceae 1236|Gammaproteobacteria M aspartate racemase ygeA GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race k141_7130_1 1036674.A28LD_1261 8.07e-76 237.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,2QFG6@267893|Idiomarinaceae 1236|Gammaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT k141_7130_2 1469245.JFBG01000020_gene1077 1.72e-18 80.9 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Preprotein translocase yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k141_10631_1 1278309.KB907108_gene1615 9.06e-240 675.0 COG1132@1|root,COG1132@2|Bacteria,1MYH7@1224|Proteobacteria,1S87B@1236|Gammaproteobacteria 1236|Gammaproteobacteria V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_10631_2 1278309.KB907108_gene1616 4.63e-61 197.0 COG1763@1|root,COG1763@2|Bacteria,1QUQC@1224|Proteobacteria,1S4HF@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mo-molybdopterin cofactor biosynthetic process - - - - - - - - - - - - - k141_15530_1 1122137.AQXF01000004_gene1409 2.96e-100 313.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind k141_1546_1 1042375.AFPL01000015_gene2203 1.62e-38 135.0 COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,1RZJZ@1236|Gammaproteobacteria,46BJ8@72275|Alteromonadaceae 1236|Gammaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_1546_2 1318628.MARLIPOL_04080 1.42e-208 585.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RRDH@1236|Gammaproteobacteria,4680W@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ring hydroxylating alpha subunit (catalytic domain) antA - 1.14.12.1,1.14.13.239 ko:K05599,ko:K22443 ko00627,ko01120,map00627,map01120 M00637 R00823,R00825 RC00192 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k141_2946_1 1123073.KB899241_gene3231 1.55e-08 58.9 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1X7J9@135614|Xanthomonadales 135614|Xanthomonadales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k141_6417_1 243233.MCA0663 3.48e-58 195.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1XE19@135618|Methylococcales 135618|Methylococcales T PFAM PhoH-like protein - - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH k141_20402_1 1278309.KB907099_gene2705 1.67e-230 638.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP3X@1236|Gammaproteobacteria,1XIGM@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K21826 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k141_3649_1 697282.Mettu_1547 8.31e-92 283.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XEHZ@135618|Methylococcales 135618|Methylococcales C FAD linked oxidases, C-terminal domain - - 1.1.5.12 ko:K03777 ko00620,ko01120,map00620,map01120 - R00704,R11591 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 k141_14113_1 2340.JV46_15490 1.35e-76 230.0 COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1J7BW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the DsrF TusC family tusC GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_11347_1 571166.KI421509_gene456 1.36e-106 313.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lolD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k141_2947_1 323848.Nmul_A2472 5.65e-62 204.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k141_15531_1 1278309.KB907100_gene2162 2.89e-20 84.7 COG1507@1|root,COG1507@2|Bacteria,1RDW4@1224|Proteobacteria,1S5CM@1236|Gammaproteobacteria,1XKAI@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF501) - - - ko:K09009 - - - - ko00000 - - - DUF501 k141_15531_2 1278309.KB907100_gene2163 1.07e-81 250.0 COG3608@1|root,COG3608@2|Bacteria,1MV55@1224|Proteobacteria,1S6VH@1236|Gammaproteobacteria,1XPHG@135619|Oceanospirillales 135619|Oceanospirillales S Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA k141_5007_2 1232683.ADIMK_4134 7.98e-134 385.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,464MH@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 k141_5007_3 1288494.EBAPG3_13350 2.09e-06 49.3 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,372K1@32003|Nitrosomonadales 28216|Betaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - NfeD k141_10633_1 519989.ECTPHS_06737 1.99e-76 243.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales 135613|Chromatiales HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - ATP-grasp_3,RLAN,RimK k141_6418_1 28258.KP05_01155 4.04e-84 264.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria 1236|Gammaproteobacteria C malate quinone oxidoreductase - - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_19676_2 870187.Thini_4032 3.81e-44 147.0 2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,1S97C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_21736_1 1278309.KB907099_gene2420 0.0 928.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XIAV@135619|Oceanospirillales 135619|Oceanospirillales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_21736_2 1278309.KB907099_gene2421 3.84e-66 213.0 COG2959@1|root,COG2959@2|Bacteria,1N3SM@1224|Proteobacteria,1S9N7@1236|Gammaproteobacteria,1XME6@135619|Oceanospirillales 135619|Oceanospirillales H enzyme of heme biosynthesis - - - - - - - - - - - - - k141_7836_1 1278309.KB907100_gene2323 5.74e-86 256.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1XK0E@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component gtrA - - - - - - - - - - - DctQ k141_7836_2 1278309.KB907100_gene2324 2.42e-112 325.0 COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,1XJTP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF416) - - - ko:K09891 - - - - ko00000 - - - DUF416 k141_7836_3 1278309.KB907100_gene2325 5.77e-37 126.0 2EKD5@1|root,3371Y@2|Bacteria,1NESA@1224|Proteobacteria,1SFNU@1236|Gammaproteobacteria,1XR2R@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7836_4 1278309.KB907100_gene2326 8.01e-52 168.0 2CDP6@1|root,32RY5@2|Bacteria,1N1TI@1224|Proteobacteria,1SC2T@1236|Gammaproteobacteria,1XKWR@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_7836_5 1278309.KB907100_gene2327 5.96e-131 378.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S364@1236|Gammaproteobacteria,1XR2Z@135619|Oceanospirillales 135619|Oceanospirillales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg k141_7836_6 1278309.KB907100_gene2328 1.37e-62 193.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1XKKD@135619|Oceanospirillales 135619|Oceanospirillales T COG0784 FOG CheY-like receiver - - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k141_7836_7 1278309.KB907100_gene2329 7.9e-66 206.0 COG0835@1|root,COG0835@2|Bacteria,1NF0B@1224|Proteobacteria,1SD1Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT CheW-like domain - - - - - - - - - - - - CheW k141_7836_8 1278309.KB907100_gene2330 4.52e-220 633.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIUV@135619|Oceanospirillales 135619|Oceanospirillales NT chemotaxis protein - - - - - - - - - - - - HAMP,MCPsignal k141_8518_1 768671.ThimaDRAFT_4052 1.53e-104 318.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k141_17578_1 1278309.KB907100_gene2171 4.21e-197 566.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1XHXZ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k141_17578_2 1232683.ADIMK_2370 1.22e-210 585.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,464JJ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_9187_1 1288826.MSNKSG1_11878 2.65e-35 121.0 COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,1SR7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k141_9187_2 1288826.MSNKSG1_11873 2.7e-296 808.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,465VE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Cytochrome_CBB3,Mo-co_dimer,Oxidored_molyb k141_9187_3 1288826.MSNKSG1_11868 2.2e-172 482.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria 1224|Proteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_9187_4 1288826.MSNKSG1_11863 2.46e-207 577.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,464C7@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0530 Ca2 Na antiporter Z012_08255 - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_9187_5 1288826.MSNKSG1_11858 8.95e-274 752.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,465Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1055 Na H antiporter NhaD and related arsenite permeases nhaD - - - - - - - - - - - CitMHS k141_9187_6 1288826.MSNKSG1_11853 0.0 972.0 COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,46A2J@72275|Alteromonadaceae 1236|Gammaproteobacteria C malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo k141_3650_1 269798.CHU_1434 1.42e-117 365.0 COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,47XZT@768503|Cytophagia 976|Bacteroidetes E B12 binding domain metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind k141_21126_1 292415.Tbd_2108 2.81e-20 90.5 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1KS7N@119069|Hydrogenophilales 119069|Hydrogenophilales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_4349_1 1237149.C900_03476 2.62e-76 245.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran k141_18985_1 880070.Cycma_2517 1.45e-128 392.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia 976|Bacteroidetes O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_14807_2 743299.Acife_0569 1.79e-53 177.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,1S5K2@1236|Gammaproteobacteria,2NC9B@225057|Acidithiobacillales 225057|Acidithiobacillales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k141_14807_3 105559.Nwat_1218 4.3e-110 326.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales 135613|Chromatiales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_14114_1 1026882.MAMP_01154 4.14e-27 115.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,460Z5@72273|Thiotrichales 72273|Thiotrichales P Voltage gated chloride channel clcA - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC k141_15532_1 671143.DAMO_0362 2.54e-81 250.0 COG2837@1|root,COG2837@2|Bacteria 2|Bacteria P iron assimilation dyp - - ko:K07223 - - - - ko00000 - - - Dyp_perox k141_11349_1 1367847.JCM7686_1981 5.28e-07 53.9 2ADQT@1|root,313G5@2|Bacteria,1PSCN@1224|Proteobacteria,2V4JJ@28211|Alphaproteobacteria,2PX7P@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_11349_2 1461694.ATO9_15130 1.71e-30 120.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria,2PD8B@252301|Oceanicola 28211|Alphaproteobacteria E Oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N k141_2948_1 713587.THITH_00145 1.44e-35 136.0 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1X17E@135613|Chromatiales 135613|Chromatiales U Pfam:T4SC - - - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC k141_2948_2 765914.ThisiDRAFT_1262 3.63e-17 83.2 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WWUD@135613|Chromatiales 135613|Chromatiales NU general secretion pathway protein D - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k141_21737_1 1415756.JQMY01000001_gene454 1.21e-27 102.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2UF3C@28211|Alphaproteobacteria,2PEQ8@252301|Oceanicola 28211|Alphaproteobacteria O Belongs to the sulfur carrier protein TusA family tusA - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA k141_21737_2 666509.RCA23_c14780 7.13e-70 219.0 COG0583@1|root,COG0583@2|Bacteria,1MV5N@1224|Proteobacteria,2TRAX@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator MA20_05050 - - - - - - - - - - - HTH_1,LysR_substrate k141_4350_1 1278309.KB907099_gene2593 9.02e-63 194.0 COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,1S8J5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Domain of unknown function (DUF1924) shp - - - - - - - - - - - DUF1924 k141_21127_1 1049564.TevJSym_aw00060 1.43e-20 94.7 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - dsrS - - - - - - - - - - - - k141_20404_1 999141.GME_03972 7.59e-121 350.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1XI46@135619|Oceanospirillales 135619|Oceanospirillales C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF k141_17579_1 998674.ATTE01000001_gene1086 1.02e-128 391.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales 72273|Thiotrichales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_5760_1 1278309.KB907109_gene3234 3.7e-56 177.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1XKGN@135619|Oceanospirillales 135619|Oceanospirillales U Preprotein translocase subunit SecG secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG k141_5760_2 1278309.KB907109_gene3233 2.82e-136 390.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1XISD@135619|Oceanospirillales 135619|Oceanospirillales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k141_5760_3 1278309.KB907109_gene3232 1.72e-276 761.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XH2Q@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_5760_4 1278309.KB907109_gene3231 1.99e-169 478.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XHU9@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind k141_5760_5 1278309.KB907109_gene3230 0.0 1107.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XIG3@135619|Oceanospirillales 135619|Oceanospirillales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_5760_6 1278309.KB907109_gene3229 3.51e-101 296.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1XHHV@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_12703_1 880070.Cycma_3347 6.13e-09 62.8 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_131_2 1288826.MSNKSG1_06023 1.05e-142 404.0 COG3638@1|root,COG3638@2|Bacteria,1RF8E@1224|Proteobacteria,1S3VW@1236|Gammaproteobacteria,46AR5@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG3638 ABC-type phosphate phosphonate transport system, ATPase component phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k141_11441_2 1288826.MSNKSG1_13502 7.42e-294 804.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,466YN@72275|Alteromonadaceae 1236|Gammaproteobacteria F COG0044 Dihydroorotase and related cyclic amidohydrolases pyrC - 3.5.2.3,3.5.2.5 ko:K01465,ko:K01466 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00051,M00546 R01993,R02425 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_11441_3 1288826.MSNKSG1_13497 4.54e-240 660.0 COG0715@1|root,COG0715@2|Bacteria,1QVPH@1224|Proteobacteria,1T2FY@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - k141_11441_4 1288826.MSNKSG1_13492 4.44e-54 169.0 COG0776@1|root,COG0776@2|Bacteria,1N18A@1224|Proteobacteria,1SAIM@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupA - - ko:K05787 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k141_11441_5 1288826.MSNKSG1_13487 1.05e-252 693.0 28M2K@1|root,2ZAH0@2|Bacteria,1R6X6@1224|Proteobacteria,1RZU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_11441_6 1288826.MSNKSG1_13482 0.0 1247.0 COG1593@1|root,COG1593@2|Bacteria,1PJM6@1224|Proteobacteria,1RPHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM k141_11441_7 1288826.MSNKSG1_13462 1.77e-64 209.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,464KD@72275|Alteromonadaceae 1236|Gammaproteobacteria H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_10759_1 1288826.MSNKSG1_12172 7.78e-160 465.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,466IR@72275|Alteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain lapD - - - - - - - - - - - EAL,GGDEF,HAMP,LapD_MoxY_N k141_7980_1 1191299.AJYX01000071_gene1191 0.000694 43.5 2E6QP@1|root,331AW@2|Bacteria,1N83E@1224|Proteobacteria,1SDRG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7980_3 412965.COSY_0206 1.22e-43 147.0 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1SDBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE k141_20539_1 1026882.MAMP_01343 1.36e-89 275.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales 72273|Thiotrichales H PFAM aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_14909_1 1278309.KB907099_gene3111 3.62e-313 857.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XI11@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_14909_2 1278309.KB907099_gene3113 6.31e-74 224.0 COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,1S49H@1236|Gammaproteobacteria,1XJHA@135619|Oceanospirillales 135619|Oceanospirillales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR k141_14909_3 1278309.KB907099_gene3114 9.46e-25 99.4 COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,1S4FU@1236|Gammaproteobacteria,1XRP3@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_3761_2 247634.GPB2148_789 4.89e-115 338.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0501 Zn-dependent protease with chaperone function Z012_09445 - - - - - - - - - - - Peptidase_M48 k141_3761_3 686340.Metal_3994 7.73e-39 142.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XE1Y@135618|Methylococcales 135618|Methylococcales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k141_264_1 998088.B565_3040 4.2e-168 511.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1Y3WV@135624|Aeromonadales 135624|Aeromonadales L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_19781_2 1123228.AUIH01000034_gene2791 4.74e-29 111.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1XJAQ@135619|Oceanospirillales 135619|Oceanospirillales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 k141_6500_1 396588.Tgr7_0827 3.94e-102 304.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k141_972_1 1122137.AQXF01000005_gene1257 4.81e-73 224.0 COG1309@1|root,COG1309@2|Bacteria,1RGJ3@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator pfiT - - - - - - - - - - - TetR_C_4,TetR_N k141_21891_1 1191523.MROS_1246 1.09e-63 207.0 COG0612@1|root,COG0612@2|Bacteria 2|Bacteria L Peptidase, M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k141_4489_1 1288826.MSNKSG1_11358 2.52e-140 417.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4673P@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k141_4489_2 1288826.MSNKSG1_11363 1.77e-260 713.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 k141_4489_3 1288826.MSNKSG1_11368 6.26e-63 192.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,467W6@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - - - - - - - - - - Iron_traffic k141_12827_1 1278309.KB907104_gene821 3.87e-115 356.0 COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XHS7@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the ClpA ClpB family - - - ko:K11907 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - AAA,AAA_2,ClpB_D2-small k141_16269_1 443152.MDG893_10916 6.41e-64 213.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,465TI@72275|Alteromonadaceae 1236|Gammaproteobacteria KLT COG0515 Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase k141_7252_1 1000565.METUNv1_00310 5.22e-15 78.6 2D5F0@1|root,32TIY@2|Bacteria,1N1FC@1224|Proteobacteria,2VYG3@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_8633_1 1278309.KB907102_gene194 0.0 1028.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XIWI@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_8633_2 1278309.KB907102_gene195 2.56e-188 527.0 COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,1RYY7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nitrilase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase k141_8633_3 1278309.KB907102_gene196 1.22e-90 266.0 COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,1S3X0@1236|Gammaproteobacteria,1XPGG@135619|Oceanospirillales 135619|Oceanospirillales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_8633_4 1278309.KB907102_gene197 5.74e-142 403.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,1RYP5@1236|Gammaproteobacteria,1XRI6@135619|Oceanospirillales 135619|Oceanospirillales K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k141_8633_6 1278309.KB907102_gene198 4.76e-262 724.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XNZE@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K05590 - - - - ko00000,ko01000,ko03009 - - - DEAD,Helicase_C k141_8633_7 1278309.KB907102_gene199 1.05e-65 221.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XHNQ@135619|Oceanospirillales 135619|Oceanospirillales K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,ResIII,SNF2_N k141_19125_1 1123360.thalar_03072 1.08e-195 553.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria 28211|Alphaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_284_3 247490.KSU1_C1031 5.42e-127 377.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2IZRY@203682|Planctomycetes 203682|Planctomycetes S Peptidase family M50 - - - - - - - - - - - - CBS,Peptidase_M50 k141_284_4 545264.KB898747_gene546 4.59e-84 254.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1WWRN@135613|Chromatiales 135613|Chromatiales P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k141_6517_2 555778.Hneap_0659 9.67e-46 162.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,1WXYC@135613|Chromatiales 135613|Chromatiales EGP Major Facilitator Superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_3101_2 187272.Mlg_2637 1.89e-29 119.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales 135613|Chromatiales M PFAM Three-deoxy-D-manno-octulosonic-acid transferase - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N,Kdo k141_19144_2 1225785.CM001983_gene2996 8.87e-165 503.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,2JD68@204037|Dickeya 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_21247_1 1337093.MBE-LCI_1272 4.41e-129 385.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2P7WM@245186|Loktanella 28211|Alphaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_16284_2 2340.JV46_18410 3.31e-38 134.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1J6GH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200 - - - - ko00000 - - - CcmH,TPR_19 k141_16284_3 1217718.ALOU01000001_gene4573 4.69e-57 184.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1K777@119060|Burkholderiaceae 28216|Betaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ccmG - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin k141_16284_4 1380358.JADJ01000007_gene3082 1.59e-20 90.9 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales 135619|Oceanospirillales O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k141_7271_2 1236541.BALL01000052_gene4347 2.52e-169 484.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,2QA3X@267890|Shewanellaceae 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_3779_1 580332.Slit_2799 5.74e-76 234.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k141_3779_2 1122134.KB893650_gene5 1.3e-08 62.8 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T5FB@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_4499_1 1266925.JHVX01000001_gene2631 4.24e-50 166.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WFS6@28216|Betaproteobacteria,372JC@32003|Nitrosomonadales 28216|Betaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC k141_4499_2 1163617.SCD_n02609 1.55e-68 217.0 COG0457@1|root,COG0457@2|Bacteria,1R85G@1224|Proteobacteria,2W1NE@28216|Betaproteobacteria 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_4499_3 1120985.AUMI01000021_gene2833 1.21e-32 131.0 COG2199@1|root,COG3706@2|Bacteria,1UYCS@1239|Firmicutes,4H3J7@909932|Negativicutes 909932|Negativicutes T Diguanylate cyclase (GGDEF) domain protein - - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - FIST,FIST_C,GGDEF k141_984_1 545276.KB898724_gene1980 7.68e-33 132.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales 135613|Chromatiales T PFAM Metal-dependent hydrolase HDOD - - - - - - - - - - - - HDOD,bPH_2 k141_18416_1 367336.OM2255_07975 2.86e-105 337.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k141_3102_1 1123393.KB891330_gene761 2.52e-19 87.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1KSCE@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k141_10008_1 1278309.KB907102_gene110 4.2e-199 555.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XI2N@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP k141_6518_1 13035.Dacsa_2388 1.85e-06 48.5 COG0667@1|root,COG0667@2|Bacteria,1G2Y9@1117|Cyanobacteria 1117|Cyanobacteria C aldo keto reductase - - 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red k141_6518_2 1265503.KB905162_gene3569 1.92e-09 62.0 COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,NMT1,dCache_1,dCache_3 k141_285_2 1283300.ATXB01000002_gene2567 5.77e-38 134.0 COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,1SASF@1236|Gammaproteobacteria,1XFJZ@135618|Methylococcales 135618|Methylococcales I COG0575 CDP-diglyceride synthetase - - - - - - - - - - - - CarS-like k141_12153_1 655815.ZPR_2636 1.01e-43 158.0 COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,1I087@117743|Flavobacteriia 976|Bacteroidetes E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k141_5145_2 1122599.AUGR01000039_gene3171 6.98e-23 95.9 COG0847@1|root,COG0847@2|Bacteria,1RHD8@1224|Proteobacteria,1SAI6@1236|Gammaproteobacteria,1XRHP@135619|Oceanospirillales 135619|Oceanospirillales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - k141_5145_3 911045.PSE_p0323 9.13e-79 240.0 COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2TUCA@28211|Alphaproteobacteria 28211|Alphaproteobacteria T pyridoxamine 5-phosphate MA20_18655 - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx k141_5145_4 911045.PSE_p0322 5.69e-90 266.0 COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K09958 - - - - ko00000 - - - DUF1348 k141_5145_5 1232683.ADIMK_3933 2.46e-97 286.0 COG2128@1|root,COG2128@2|Bacteria,1RASD@1224|Proteobacteria,1S391@1236|Gammaproteobacteria,466JY@72275|Alteromonadaceae 1236|Gammaproteobacteria O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k141_5145_6 1232683.ADIMK_3934 4.08e-116 339.0 COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,1RMJ5@1236|Gammaproteobacteria,464B4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate k141_19145_1 28229.ND2E_0401 6.45e-102 308.0 COG5635@1|root,COG5635@2|Bacteria,1MY1P@1224|Proteobacteria,1RZKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Nacht domain - - - - - - - - - - - - - k141_15630_1 1278309.KB907099_gene2873 7.35e-174 491.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RQZ8@1236|Gammaproteobacteria,1XIK5@135619|Oceanospirillales 135619|Oceanospirillales C Oxidoreductase FAD-binding domain - - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_1708_1 347834.RHE_CH03193 4.05e-35 135.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria,4BB4B@82115|Rhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator ampR GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010604,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0032268,GO:0032270,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0043455,GO:0043565,GO:0043900,GO:0043901,GO:0044424,GO:0044464,GO:0045862,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051173,GO:0051222,GO:0051223,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1900190,GO:1900191,GO:1900231,GO:1900232,GO:1900376,GO:1900378,GO:1901363,GO:1903506,GO:1903530,GO:1903532,GO:1904951,GO:2000112,GO:2001141 - ko:K17850 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko03000 - - - HTH_1,LysR_substrate k141_11455_1 1121441.AUCX01000018_gene1452 1.07e-95 290.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2M99U@213115|Desulfovibrionales 28221|Deltaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2848 Pribosyl_synth,Pribosyltran_N k141_14227_1 1288826.MSNKSG1_16251 6.82e-133 384.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,466KI@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_14227_2 1288826.MSNKSG1_16246 1.43e-265 739.0 COG4206@1|root,COG4206@2|Bacteria,1QUPS@1224|Proteobacteria,1T2KE@1236|Gammaproteobacteria,467H2@72275|Alteromonadaceae 1236|Gammaproteobacteria H TonB dependent receptor oprC - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_3780_1 94624.Bpet3409 8.33e-104 324.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3T1CY@506|Alcaligenaceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenases fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k141_8008_1 1122599.AUGR01000017_gene2995 3.39e-15 73.6 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1XH58@135619|Oceanospirillales 135619|Oceanospirillales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_8008_2 1278309.KB907105_gene1532 1.04e-136 391.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XHGQ@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_14925_1 1121403.AUCV01000050_gene2094 2.14e-109 335.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,42PKT@68525|delta/epsilon subdivisions,2WK85@28221|Deltaproteobacteria,2MPTE@213118|Desulfobacterales 28221|Deltaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k141_15631_1 1469613.JT55_04430 2.04e-26 107.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,2U1T4@28211|Alphaproteobacteria,3FDD9@34008|Rhodovulum 28211|Alphaproteobacteria K helix_turn_helix, arabinose operon control protein pobR - - ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 k141_16285_1 862908.BMS_1128 1.98e-78 238.0 COG1432@1|root,COG1432@2|Bacteria,1QC1U@1224|Proteobacteria,42TAH@68525|delta/epsilon subdivisions,2WPYX@28221|Deltaproteobacteria 28221|Deltaproteobacteria S NYN domain - - - - - - - - - - - - NYN k141_20558_1 1500301.JQMF01000008_gene840 4.49e-20 95.5 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4B95Y@82115|Rhizobiaceae 28211|Alphaproteobacteria T GHKL domain fixL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_9 k141_4500_1 1288826.MSNKSG1_15946 5.66e-180 501.0 COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1S1FQ@1236|Gammaproteobacteria,46CHF@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.159,1.1.1.206 ko:K00076,ko:K08081 ko00121,ko00960,ko01100,ko01110,map00121,map00960,map01100,map01110 - R02832 RC00144 ko00000,ko00001,ko01000 - - - adh_short_C2 k141_17739_1 1049564.TevJSym_aa02480 9.62e-81 251.0 COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1J7WK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_10010_1 1500893.JQNB01000001_gene1262 3.24e-38 136.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X3ZT@135614|Xanthomonadales 135614|Xanthomonadales C Heme copper-type cytochrome quinol oxidase subunit 3 cox3 - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k141_10010_3 1384056.N787_06955 1.73e-07 51.6 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X34C@135614|Xanthomonadales 135614|Xanthomonadales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_6519_1 1121434.AULY01000011_gene1739 9.29e-14 79.0 COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MADW@213115|Desulfovibrionales 28221|Deltaproteobacteria KT SMART Protein phosphatase - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_2,SSF,SpoIIE k141_14926_1 977880.RALTA_A1406 7.64e-32 122.0 COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,2VKVW@28216|Betaproteobacteria,1K3JQ@119060|Burkholderiaceae 28216|Betaproteobacteria M MltA-interacting protein MipA - - - - - - - - - - - - MipA k141_10229_1 1232683.ADIMK_3919 6.77e-95 291.0 COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria 1224|Proteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - k141_16491_1 1117647.M5M_14340 6.31e-24 105.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1J531@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M M COG4775 Outer membrane protein protective antigen OMA87 - - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_7463_1 1278309.KB907102_gene168 1.18e-66 209.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,1XK5F@135619|Oceanospirillales 135619|Oceanospirillales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_7463_2 1278309.KB907102_gene167 7.95e-143 405.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,1XJQZ@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin k141_7463_3 1278309.KB907102_gene166 2.91e-48 160.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria,1XJJP@135619|Oceanospirillales 135619|Oceanospirillales S Haloacid dehalogenase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_3308_1 455436.DS989813_gene1069 1.39e-63 201.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,4669C@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein Z012_09465 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc k141_19332_2 400668.Mmwyl1_3037 3.05e-174 490.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1XKDZ@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_19332_3 400668.Mmwyl1_3038 1.07e-150 430.0 COG0491@1|root,COG0491@2|Bacteria,1NGQE@1224|Proteobacteria,1RMI3@1236|Gammaproteobacteria,1XIH2@135619|Oceanospirillales 135619|Oceanospirillales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k141_19332_4 400668.Mmwyl1_3039 1.27e-49 163.0 COG3531@1|root,COG3531@2|Bacteria,1RA76@1224|Proteobacteria,1RSJ2@1236|Gammaproteobacteria,1XS76@135619|Oceanospirillales 135619|Oceanospirillales O Protein-disulfide isomerase - - - ko:K07396 - - - - ko00000 - - - DSBA k141_1881_1 994573.T472_0205120 1.41e-07 62.4 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes 1239|Firmicutes M domain protein - - - - - - - - - - - - DUF11 k141_8785_1 270374.MELB17_19681 3.22e-16 75.1 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,46894@72275|Alteromonadaceae 1236|Gammaproteobacteria S Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - - - - - - - - - - PilZ k141_8785_2 395493.BegalDRAFT_1683 4.04e-154 446.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,45ZQZ@72273|Thiotrichales 72273|Thiotrichales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - ATPase,ChlI k141_20696_1 398578.Daci_2254 3.13e-56 188.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,4AB9E@80864|Comamonadaceae 28216|Betaproteobacteria O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family coxI - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI k141_17935_1 1288826.MSNKSG1_13247 1.17e-106 318.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,1RR20@1236|Gammaproteobacteria,4656R@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 k141_17935_2 1288826.MSNKSG1_13252 5.05e-185 514.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,4672Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S ATPase (AAA superfamily) - - - ko:K06923 - - - - ko00000 - - - DUF815 k141_17935_3 1288826.MSNKSG1_13257 3.47e-79 236.0 COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,46733@72275|Alteromonadaceae 1236|Gammaproteobacteria G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992 MGS k141_2550_1 395019.Bmul_0549 1.03e-40 144.0 2CJRU@1|root,2ZUZ5@2|Bacteria,1RERA@1224|Proteobacteria,2W0IF@28216|Betaproteobacteria,1K16B@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_14358_1 1249627.D779_1728 3.31e-82 249.0 COG1051@1|root,COG1051@2|Bacteria,1RC3I@1224|Proteobacteria,1S34Y@1236|Gammaproteobacteria,1WY35@135613|Chromatiales 135613|Chromatiales F NUDIX domain - - - - - - - - - - - - NUDIX k141_18590_1 1121937.AUHJ01000001_gene494 3.62e-18 84.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,465KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Aminotran_3 k141_18590_2 379731.PST_2671 2.82e-52 173.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1Z0IE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_2444 PALP k141_11629_1 633131.TR2A62_2121 3.57e-110 321.0 COG1011@1|root,COG1011@2|Bacteria,1NYX7@1224|Proteobacteria,2TVNX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 k141_15848_1 1278309.KB907108_gene1589 2.57e-34 131.0 COG4447@1|root,COG4447@2|Bacteria,1R5ZV@1224|Proteobacteria,1S0FG@1236|Gammaproteobacteria,1XMK0@135619|Oceanospirillales 135619|Oceanospirillales S Photosynthesis system II assembly factor YCF48 - - - - - - - - - - - - PSII_BNR k141_15848_2 237609.PSAKL28_05790 2.52e-133 387.0 COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,1RZTU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_12369_1 1266914.ATUK01000011_gene2493 8.15e-57 186.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1WX04@135613|Chromatiales 135613|Chromatiales D PFAM Cobyrinic acid a,c-diamide synthase - - - - - - - - - - - - AAA_31 k141_12369_2 999141.GME_13698 6.18e-48 160.0 COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,1XKDU@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis signal transduction protein cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_12369_3 395493.BegalDRAFT_1551 7.35e-68 228.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales 72273|Thiotrichales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_10954_1 1121921.KB898708_gene1532 1.21e-11 69.7 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,2PNEH@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria D ZipA, C-terminal domain (FtsZ-binding) zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k141_10954_2 2340.JV46_14410 1.56e-118 375.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1J4IV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k141_17936_1 1298593.TOL_0790 4.09e-111 325.0 COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria 1236|Gammaproteobacteria T membrane-anchored protein conserved in bacteria - - - - - - - - - - - - DUF347 k141_21419_2 269798.CHU_0864 5.44e-42 151.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k141_3310_1 395493.BegalDRAFT_1784 8.6e-88 273.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4601I@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM cytochrome c oxidase accessory protein FixG - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_6692_1 1122236.KB905142_gene414 1.92e-84 251.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2VQ5F@28216|Betaproteobacteria,2KNUD@206350|Nitrosomonadales 206350|Nitrosomonadales P Cyanate lyase C-terminal domain, Cyanate hydratase - - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase k141_4693_1 1121935.AQXX01000142_gene2234 3.56e-47 173.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHWH@135619|Oceanospirillales 135619|Oceanospirillales NT Chemotaxis protein histidine kinase and related - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_16494_1 1122137.AQXF01000004_gene1547 2.83e-82 251.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k141_15850_1 557598.LHK_03097 1.99e-19 92.8 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,2KPT0@206351|Neisseriales 206351|Neisseriales O Psort location CytoplasmicMembrane, score - - - ko:K07399 - - - - ko00000 - - - ResB k141_21439_1 351348.Maqu_1992 6.25e-18 77.8 COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria,468IN@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) rsbV - - ko:K20978 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001 - - - STAS_2 k141_19978_1 1278309.KB907107_gene1750 1.81e-98 292.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1XJVZ@135619|Oceanospirillales 135619|Oceanospirillales N Required for flagellar hook formation. May act as a scaffolding protein - - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k141_19978_2 1278309.KB907107_gene1751 2.65e-85 253.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,1XJIJ@135619|Oceanospirillales 135619|Oceanospirillales N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k141_1898_1 1288826.MSNKSG1_06963 4.59e-108 325.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,465VX@72275|Alteromonadaceae 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - GNVR,Wzz k141_1898_2 1288826.MSNKSG1_06958 1.84e-204 566.0 COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,4649B@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0489 ATPases involved in chromosome partitioning - - - - - - - - - - - - AAA_31,CbiA k141_11645_1 1121935.AQXX01000141_gene2128 3.81e-41 143.0 COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,1S0D0@1236|Gammaproteobacteria,1XIUX@135619|Oceanospirillales 135619|Oceanospirillales P PFAM binding-protein-dependent transport systems inner membrane component gtsB - - ko:K17316 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_11645_2 1121935.AQXX01000141_gene2127 3.66e-158 449.0 COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,1RZHT@1236|Gammaproteobacteria,1XHVR@135619|Oceanospirillales 135619|Oceanospirillales P PFAM binding-protein-dependent transport systems inner membrane component gtsC - - ko:K17317 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k141_11645_3 349521.HCH_06079 6.99e-172 490.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XIFT@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the ABC transporter superfamily - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 k141_11645_4 1349767.GJA_1472 4e-64 212.0 COG2207@1|root,COG2207@2|Bacteria,1NDY5@1224|Proteobacteria,2VIGE@28216|Betaproteobacteria,474TW@75682|Oxalobacteraceae 28216|Betaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 k141_1225_1 314262.MED193_21269 4.5e-134 385.0 COG1082@1|root,COG1082@2|Bacteria,1MW1Z@1224|Proteobacteria,2U51B@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Sugar phosphate - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N k141_22093_2 1278309.KB907109_gene3291 1.31e-101 295.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1XJ74@135619|Oceanospirillales 135619|Oceanospirillales E acetolactate synthase ilvH - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C k141_22093_3 1278309.KB907109_gene3290 1.23e-206 583.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XHV2@135619|Oceanospirillales 135619|Oceanospirillales E acetolactate synthase ilvB-1 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_8215_1 1288826.MSNKSG1_06448 1.25e-96 287.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,465WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the precorrin methyltransferase family cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_3999 CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase k141_8215_2 1288826.MSNKSG1_06443 2.97e-148 423.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae 1236|Gammaproteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 DAHP_synth_1 k141_9476_2 1278309.KB907109_gene3263 3.31e-45 160.0 COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1SWJ5@1236|Gammaproteobacteria,1XMWK@135619|Oceanospirillales 135619|Oceanospirillales M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - TonB_C k141_9476_3 948106.AWZT01000036_gene1737 9.72e-18 79.7 COG2146@1|root,COG2146@2|Bacteria,1PTAZ@1224|Proteobacteria,2WDC6@28216|Betaproteobacteria,1K9ZG@119060|Burkholderiaceae 28216|Betaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske k141_9476_4 1278309.KB907109_gene3261 3.95e-110 320.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XJBB@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA k141_13074_1 1278309.KB907100_gene1830 0.0 1034.0 COG0304@1|root,COG0304@2|Bacteria,1MV67@1224|Proteobacteria,1RMXJ@1236|Gammaproteobacteria,1XHM8@135619|Oceanospirillales 135619|Oceanospirillales IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.180 ko:K18473 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k141_13074_2 1278309.KB907100_gene1829 2.52e-116 337.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1XJH9@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - Gly-zipper_Omp,OMP_b-brl,OmpA k141_13074_3 1123326.JFBL01000015_gene2460 1.52e-25 114.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SZE@68525|delta/epsilon subdivisions 1224|Proteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K21022,ko:K21085 ko02025,ko02026,map02025,map02026 - - - ko00000,ko00001,ko01000 - - - CBS,GGDEF k141_13074_5 946362.XP_004997743.1 8.28e-31 130.0 COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta 33154|Opisthokonta Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k141_514_1 530564.Psta_4013 5.34e-16 85.1 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes 203682|Planctomycetes T FHA domain - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - FHA,GAF_2,SpoIIE k141_6030_1 398767.Glov_0766 5.63e-85 262.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family gnnB - - - - - - - - - - iAF987.Gmet_2351 DegT_DnrJ_EryC1 k141_17957_1 290398.Csal_2577 2.5e-79 241.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1XIY0@135619|Oceanospirillales 135619|Oceanospirillales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_17957_2 323261.Noc_2017 1.99e-45 154.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1WXJF@135613|Chromatiales 135613|Chromatiales E HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - - - - - - - - - - HAD k141_3948_1 1049564.TevJSym_ac01470 3.1e-16 74.3 COG2940@1|root,COG2940@2|Bacteria 2|Bacteria K SET domain CP_0991 - - ko:K07117 - - - - ko00000 - - - SET k141_13762_1 1232683.ADIMK_0298 8.12e-42 149.0 COG2207@1|root,COG2207@2|Bacteria,1RA7U@1224|Proteobacteria,1S2Q5@1236|Gammaproteobacteria,469NW@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins benR - - - - - - - - - - - AraC_binding_2,HTH_18 k141_13762_2 1232683.ADIMK_2278 1.53e-105 319.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,464VI@72275|Alteromonadaceae 1236|Gammaproteobacteria E Histidine ammonia-lyase hutH GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic k141_1899_1 1278309.KB907099_gene2765 5.34e-39 131.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1S5WM@1236|Gammaproteobacteria,1XJYB@135619|Oceanospirillales 135619|Oceanospirillales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k141_7481_1 572477.Alvin_2064 1.58e-228 652.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH k141_22094_2 396588.Tgr7_1482 4.43e-15 70.9 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales 135613|Chromatiales S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 k141_22094_3 547045.NEISICOT_00288 5.2e-18 80.5 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,2KQ3X@206351|Neisseriales 206351|Neisseriales C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17 k141_12393_1 1266909.AUAG01000010_gene2612 1.07e-154 457.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales 135613|Chromatiales C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2 k141_12393_2 648757.Rvan_0591 1.29e-28 110.0 2E6CU@1|root,3310G@2|Bacteria,1NBK1@1224|Proteobacteria,2UGBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_21440_3 365046.Rta_20400 3.29e-50 164.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,4A9KP@80864|Comamonadaceae 28216|Betaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_15857_1 1288826.MSNKSG1_09838 5.54e-172 481.0 COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,464AP@72275|Alteromonadaceae 1236|Gammaproteobacteria S DUF1338 - - - - - - - - - - - - DUF1338 k141_15857_2 1288826.MSNKSG1_09833 5.87e-255 701.0 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,4661T@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG3138 Arginine ornithine N-succinyltransferase beta subunit astA - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k141_15857_3 1288826.MSNKSG1_09828 2.53e-88 261.0 COG1522@1|root,COG1522@2|Bacteria,1RH53@1224|Proteobacteria,1S493@1236|Gammaproteobacteria,466UQ@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1522 Transcriptional regulators - - - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k141_15857_5 1288826.MSNKSG1_09823 0.0 1112.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,464ZH@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) fadD - - - - - - - - - - - AMP-binding k141_15857_7 351348.Maqu_2886 7.23e-189 527.0 COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,1RZTS@1236|Gammaproteobacteria,468M2@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_15857_8 1288826.MSNKSG1_09808 5.4e-169 471.0 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,46401@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - SLT k141_14508_1 314345.SPV1_08456 4.97e-65 218.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria 1224|Proteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - - - - - - - - - - XFP,XFP_N k141_4846_1 269799.Gmet_2352 5.84e-94 284.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C k141_4846_2 1410653.JHVC01000005_gene2562 1.62e-07 52.8 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,36DUG@31979|Clostridiaceae 186801|Clostridia E Belongs to the DegT DnrJ EryC1 family degT1 - - - - - - - - - - - DegT_DnrJ_EryC1 k141_8950_1 107636.JQNK01000009_gene3567 4.07e-89 278.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,36ZN0@31993|Methylocystaceae 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_8950_2 1278309.KB907105_gene1497 1.6e-144 415.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XIT5@135619|Oceanospirillales 135619|Oceanospirillales S permease lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k141_22244_2 1227276.HMPREF9148_00807 3.82e-16 76.3 COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,2FM7Z@200643|Bacteroidia 976|Bacteroidetes G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim k141_16642_2 243365.CV_0222 2.15e-28 110.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,2VTQI@28216|Betaproteobacteria,2KR5F@206351|Neisseriales 206351|Neisseriales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_21570_1 981336.F944_02787 1.73e-90 288.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3NIKD@468|Moraxellaceae 1236|Gammaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_633_1 1305735.JAFT01000005_gene2034 1.4e-71 236.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2PDAN@252301|Oceanicola 28211|Alphaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_13917_1 545276.KB898732_gene2480 1.06e-38 138.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM k141_13917_2 927677.ALVU02000004_gene4790 1.74e-46 168.0 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H57M@1142|Synechocystis 1117|Cyanobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GGDEF,PAS_3,PAS_9 k141_15195_1 1232683.ADIMK_3867 2.11e-66 206.0 COG3195@1|root,COG3195@2|Bacteria,1RH9S@1224|Proteobacteria,1S25P@1236|Gammaproteobacteria,468I3@72275|Alteromonadaceae 1236|Gammaproteobacteria S OHCU decarboxylase uraD - - - - - - - - - - - OHCU_decarbox k141_15195_2 1232683.ADIMK_3866 1.2e-207 575.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,46542@72275|Alteromonadaceae 1236|Gammaproteobacteria G xylanase chitin deacetylase puuE - 3.5.1.104,3.5.1.41,3.5.2.5 ko:K01452,ko:K16842,ko:K22278 ko00230,ko00520,ko01100,ko01120,map00230,map00520,map01100,map01120 M00546 R02333,R02425 RC00166,RC00300,RC00680 ko00000,ko00001,ko00002,ko01000 - - - Polysacc_deac_1 k141_6799_1 765911.Thivi_4235 3.03e-101 317.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria,1X081@135613|Chromatiales 135613|Chromatiales P PFAM von Willebrand factor type A - - - - - - - - - - - - VWA k141_6799_2 1123401.JHYQ01000015_gene1399 1.25e-59 191.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,461Q0@72273|Thiotrichales 72273|Thiotrichales S CbbQ/NirQ/NorQ C-terminal - - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C k141_9636_1 1046724.KB889919_gene208 2.78e-08 56.2 COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,467VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Type IV Pilus-assembly protein W pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW k141_9636_2 935863.AWZR01000002_gene973 1.51e-10 63.9 COG4726@1|root,COG4726@2|Bacteria,1N7KP@1224|Proteobacteria,1SW23@1236|Gammaproteobacteria,1X8MK@135614|Xanthomonadales 135614|Xanthomonadales NU PilX N-terminal - - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX,PilX_N k141_19458_1 1278309.KB907102_gene154 7.7e-212 594.0 COG4857@1|root,COG4857@2|Bacteria,1MXBW@1224|Proteobacteria,1RMDV@1236|Gammaproteobacteria,1XIVK@135619|Oceanospirillales 135619|Oceanospirillales F Phosphotransferase enzyme family mtnK - 2.7.1.100 ko:K00899 ko00270,ko01100,map00270,map01100 M00034 R04143 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APH k141_19458_2 1122599.AUGR01000014_gene510 2.41e-170 484.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1XICP@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B k141_19458_3 1168065.DOK_01089 7.17e-71 219.0 COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1J672@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_00643 ARD k141_19458_4 1122599.AUGR01000014_gene516 1.23e-98 293.0 COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1XJT4@135619|Oceanospirillales 135619|Oceanospirillales E Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC - 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase k141_19458_5 1122599.AUGR01000014_gene517 2.25e-95 283.0 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1XJJH@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.1.1.104,4.2.1.109 ko:K08964,ko:K22130 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k141_19458_6 1026882.MAMP_02311 3.29e-215 605.0 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1T5FQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF k141_19458_7 1278309.KB907102_gene151 9.63e-180 507.0 COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RMUB@1236|Gammaproteobacteria,1XHXN@135619|Oceanospirillales 135619|Oceanospirillales EJ PFAM Asparaginase glutaminase ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase k141_19458_8 1278309.KB907102_gene150 4.89e-214 594.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XII3@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_20806_1 396588.Tgr7_0039 7.03e-21 95.9 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RWW8@1236|Gammaproteobacteria,1X085@135613|Chromatiales 135613|Chromatiales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA k141_20806_2 1236541.BALL01000052_gene4347 9.62e-27 107.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,2QA3X@267890|Shewanellaceae 1236|Gammaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_10414_1 936136.ARRT01000006_gene4869 3.08e-70 226.0 COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,2TR59@28211|Alphaproteobacteria,4B7NK@82115|Rhizobiaceae 28211|Alphaproteobacteria S Transposase - - - - - - - - - - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 k141_10414_2 1207063.P24_18789 3.14e-70 212.0 COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,2U7MB@28211|Alphaproteobacteria,2JTIQ@204441|Rhodospirillales 204441|Rhodospirillales L IS66 Orf2 like protein - - - - - - - - - - - - TnpB_IS66 k141_6181_1 1279017.AQYJ01000026_gene171 3.81e-37 151.0 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS k141_4847_2 1537994.JQFW01000015_gene1923 4.79e-70 229.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k141_3455_1 491952.Mar181_1945 2.88e-21 89.0 COG3915@1|root,COG3915@2|Bacteria,1RHJS@1224|Proteobacteria,1S0M5@1236|Gammaproteobacteria,1XS9X@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - Oxidored_molyb k141_12544_1 765911.Thivi_4358 1.23e-15 73.9 COG0680@1|root,COG0680@2|Bacteria,1RGFM@1224|Proteobacteria,1S4XN@1236|Gammaproteobacteria,1WY9T@135613|Chromatiales 135613|Chromatiales C PFAM Peptidase A31, hydrogen uptake protein - - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI k141_12544_3 1123401.JHYQ01000005_gene245 6.75e-113 335.0 COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,462CC@72273|Thiotrichales 72273|Thiotrichales C Hydrogenase (NiFe) small subunit HydA - - 1.12.5.1 ko:K05927 - - - - ko00000,ko01000 - - - NiFe_hyd_SSU_C,Oxidored_q6 k141_14509_1 1265313.HRUBRA_00798 3.78e-52 178.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1J5K7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion macA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_14509_2 697282.Mettu_4275 2.09e-29 110.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XDVV@135618|Methylococcales 135618|Methylococcales V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_16002_1 1227349.C170_25882 7.55e-10 64.7 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HA6I@91061|Bacilli,26QR6@186822|Paenibacillaceae 91061|Bacilli C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - - - - - - - - - - Oxidored_FMN k141_22245_1 1123393.KB891333_gene2507 6.46e-98 295.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales 119069|Hydrogenophilales G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK k141_13918_2 1122164.JHWF01000016_gene1566 3.51e-44 149.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1JDAN@118969|Legionellales 118969|Legionellales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ k141_16644_1 398580.Dshi_2388 7.25e-22 100.0 COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,2TR9F@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,T2SSE_N k141_8951_1 1122599.AUGR01000017_gene2942 1.91e-48 163.0 2CCB7@1|root,32RV9@2|Bacteria,1N236@1224|Proteobacteria,1S9YE@1236|Gammaproteobacteria,1XQBC@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8951_2 1229172.JQFA01000004_gene1928 1.01e-24 100.0 COG0551@1|root,COG0551@2|Bacteria,1G9Z5@1117|Cyanobacteria,1HFAU@1150|Oscillatoriales 1117|Cyanobacteria L Protein of unknown function (DUF2726) - - - - - - - - - - - - DUF2726 k141_12545_2 740709.A10D4_12488 1.52e-67 224.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,2QF6X@267893|Idiomarinaceae 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k141_3456_1 543728.Vapar_3947 5.62e-87 272.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,4AEXG@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM Glycosyl transferase, family 2 - - - ko:K11936 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 - Cellulose_synt,Glyco_tranf_2_3,Glycos_transf_2 k141_20807_1 1502851.FG93_03286 2.54e-21 100.0 COG1414@1|root,COG3386@1|root,COG1414@2|Bacteria,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2U3WG@28211|Alphaproteobacteria,3K6E3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K SMP-30/Gluconolaconase/LRE-like region - - - ko:K14274 ko00040,map00040 - R02427 RC00713 ko00000,ko00001,ko01000 - - - HTH_IclR,IclR,SGL k141_19459_1 1278309.KB907102_gene135 1.68e-12 73.6 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XHNH@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_11128_1 1278309.KB907100_gene1889 9.3e-21 87.4 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1XJ7H@135619|Oceanospirillales 135619|Oceanospirillales S Uncharacterised protein family (UPF0227) - - - ko:K07000 - - - - ko00000 - - - UPF0227 k141_11128_2 1278309.KB907100_gene1890 1.33e-115 338.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1XJ9U@135619|Oceanospirillales 135619|Oceanospirillales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos k141_11128_3 1278309.KB907100_gene1891 6.53e-96 280.0 COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1S55I@1236|Gammaproteobacteria,1XRFC@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1249) - - - ko:K09920 - - - - ko00000 - - - DUF1249 k141_11128_4 1278309.KB907100_gene1892 2.15e-26 101.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XK4I@135619|Oceanospirillales 135619|Oceanospirillales L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_10415_1 1122599.AUGR01000002_gene3396 2.24e-40 140.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,1XJCN@135619|Oceanospirillales 135619|Oceanospirillales T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k141_10415_2 156578.ATW7_15764 2.57e-29 114.0 COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1SR53@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - - k141_2700_1 1515746.HR45_04930 1.14e-88 265.0 COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria,2Q9FI@267890|Shewanellaceae 1236|Gammaproteobacteria S Bacterial transferase hexapeptide (six repeats) sat - - ko:K18234 - - - - ko00000,ko01000,ko01504 - - - Hexapep k141_2700_2 224911.27351058 8.48e-26 102.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,2TTIW@28211|Alphaproteobacteria,3JRBF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Formate/nitrite transporter MA20_17080 - - - - - - - - - - - Form_Nir_trans k141_22246_1 1255043.TVNIR_2974 2.73e-89 270.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Aldo keto - - - - - - - - - - - - Aldo_ket_red k141_6182_1 1049564.TevJSym_bm00130 8.36e-135 403.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1J4GN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N k141_18768_1 1278309.KB907106_gene1245 1.8e-85 260.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RR72@1236|Gammaproteobacteria,1XHDP@135619|Oceanospirillales 135619|Oceanospirillales G TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP k141_18768_2 1278309.KB907106_gene1244 2.08e-307 846.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIFZ@135619|Oceanospirillales 135619|Oceanospirillales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - DUF3365,HAMP,MCPsignal k141_16003_1 396588.Tgr7_3044 5.57e-83 253.0 COG0515@1|root,COG0515@2|Bacteria,1NUIB@1224|Proteobacteria 1224|Proteobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase k141_5533_1 1278309.KB907104_gene891 4.88e-17 79.7 COG3064@1|root,COG3064@2|Bacteria,1MZUF@1224|Proteobacteria,1S95Z@1236|Gammaproteobacteria,1XKQT@135619|Oceanospirillales 135619|Oceanospirillales M SprA-related family - - - - - - - - - - - - SprA-related k141_5533_2 1278309.KB907104_gene890 8.88e-41 135.0 2EKEJ@1|root,33E4R@2|Bacteria,1NN8J@1224|Proteobacteria,1SJEW@1236|Gammaproteobacteria,1XMWD@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_5533_3 1278309.KB907104_gene889 1.05e-135 387.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1XJD7@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 k141_5533_4 1278309.KB907104_gene888 1.4e-151 430.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1XJ9G@135619|Oceanospirillales 135619|Oceanospirillales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_25 k141_5533_5 425104.Ssed_0176 3.47e-27 111.0 COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,2Q9G2@267890|Shewanellaceae 1236|Gammaproteobacteria S The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:0090499,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - iBWG_1329.BWG_3103,iECBD_1354.ECBD_0333,iECDH10B_1368.ECDH10B_3587,iECDH1ME8569_1439.ECDH1ME8569_3291,iETEC_1333.ETEC_3662,iEcDH1_1363.EcDH1_0301,iJO1366.b3412,iY75_1357.Y75_RS20155 Abhydrolase_1,Abhydrolase_6 k141_9638_1 163908.KB235896_gene194 0.000354 42.4 COG0499@1|root,COG0499@2|Bacteria,1G1MN@1117|Cyanobacteria,1HIF4@1161|Nostocales 1117|Cyanobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k141_9638_2 314271.RB2654_01980 1.38e-23 92.4 COG0640@1|root,COG0640@2|Bacteria,1N10H@1224|Proteobacteria,2UBRH@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional - - - - - - - - - - - - HTH_20 k141_14511_1 1278309.KB907100_gene1956 1.17e-128 375.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XMZ2@135619|Oceanospirillales 135619|Oceanospirillales E Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 k141_3457_1 472759.Nhal_2480 2.84e-53 179.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1WXJN@135613|Chromatiales 135613|Chromatiales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k141_3457_2 1230476.C207_00291 5.88e-10 60.8 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,3JSUZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I enoyl-CoA hydratase isomerase MA20_44845 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k141_10416_1 1232683.ADIMK_4110 4.26e-67 213.0 COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,1SBTI@1236|Gammaproteobacteria,46BV1@72275|Alteromonadaceae 1236|Gammaproteobacteria T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp k141_13235_2 1386089.N865_07180 8.54e-26 107.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - - - - - - - - - - Abi k141_1375_1 1278309.KB907101_gene803 6.41e-15 67.8 28QQX@1|root,2ZD6C@2|Bacteria,1P899@1224|Proteobacteria,1SVKS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_1375_2 1278309.KB907101_gene802 1.98e-180 505.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1XI03@135619|Oceanospirillales 135619|Oceanospirillales I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_1375_3 1123514.KB905899_gene1198 2.5e-28 116.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,463MS@72273|Thiotrichales 72273|Thiotrichales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_2002_1 1278309.KB907110_gene3179 1.18e-27 109.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1XKK2@135619|Oceanospirillales 135619|Oceanospirillales S MJ0042 family finger-like protein - - - - - - - - - - - - DUF3426,zinc_ribbon_5 k141_2002_2 1278309.KB907110_gene3178 1.89e-199 554.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1XHE4@135619|Oceanospirillales 135619|Oceanospirillales J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k141_16025_1 2340.JV46_16560 3.44e-09 56.6 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1J6HM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k141_16025_2 317025.Tcr_1570 1.87e-131 384.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales 72273|Thiotrichales H PFAM aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_17357_1 1122194.AUHU01000002_gene2949 1.34e-78 240.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,466N6@72275|Alteromonadaceae 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin k141_17357_2 1323663.AROI01000009_gene3636 1.14e-49 170.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L dna polymerase iii holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_16663_1 395493.BegalDRAFT_0901 7.46e-197 552.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_2014_1 1163617.SCD_n01945 1.23e-56 195.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria 28216|Betaproteobacteria S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH k141_1441_1 1382304.JNIL01000001_gene307 2.92e-69 230.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,27813@186823|Alicyclobacillaceae 91061|Bacilli KT Sigma-54 interaction domain bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat k141_9113_1 697282.Mettu_0846 1.39e-40 141.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XEB3@135618|Methylococcales 135618|Methylococcales E subfamily IB - - - - - - - - - - - - HAD k141_9113_2 631362.Thi970DRAFT_02736 1.62e-48 162.0 COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,1X2U2@135613|Chromatiales 135613|Chromatiales F Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX k141_11896_1 1121033.AUCF01000010_gene4530 5.13e-23 91.7 COG2168@1|root,COG2168@2|Bacteria,1Q1N2@1224|Proteobacteria,2UGTE@28211|Alphaproteobacteria,2JXP6@204441|Rhodospirillales 204441|Rhodospirillales P DsrH like protein - - - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_20987_1 1304888.ATWF01000001_gene1090 6.45e-89 284.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2GF7H@200930|Deferribacteres 200930|Deferribacteres T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc k141_1442_1 1184267.A11Q_865 2.09e-53 176.0 COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM class II aldolase adducin family protein - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II k141_7031_1 522373.Smlt0627 1.68e-28 108.0 COG2246@1|root,COG2246@2|Bacteria,1NA3W@1224|Proteobacteria,1SAZZ@1236|Gammaproteobacteria,1X7SI@135614|Xanthomonadales 135614|Xanthomonadales S GtrA-like protein - - - - - - - - - - - - GtrA k141_7031_2 395493.BegalDRAFT_2568 3.3e-73 235.0 COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,1S0R5@1236|Gammaproteobacteria 1236|Gammaproteobacteria H amine oxidase - - - - - - - - - - - - Amino_oxidase k141_4208_1 1288826.MSNKSG1_01223 7.4e-170 488.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,46499@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0608 Single-stranded DNA-specific exonuclease recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 k141_4208_2 1288826.MSNKSG1_01218 2.57e-261 720.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,463ZB@72275|Alteromonadaceae 1236|Gammaproteobacteria E Threonine synthase thrC GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025 PALP,Thr_synth_N k141_5635_1 1123228.AUIH01000009_gene1939 2.42e-48 170.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_18878_1 1288826.MSNKSG1_14167 4.37e-164 472.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein ctpH - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_17454_2 1134474.O59_004070 1.58e-50 173.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S type VI secretion protein impJ2 - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k141_11228_1 1384054.N790_09125 5.61e-52 182.0 COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,1R64W@1224|Proteobacteria,1RZ3W@1236|Gammaproteobacteria,1X59R@135614|Xanthomonadales 135614|Xanthomonadales L Ribonuclease - - - - - - - - - - - - Big_5,Endonuclease_1,LTD k141_14707_1 83406.HDN1F_34760 2.49e-18 94.0 COG3297@1|root,COG3297@2|Bacteria,1N3RU@1224|Proteobacteria,1T05Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria U involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_13307_2 1205680.CAKO01000002_gene2644 2.19e-28 114.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2JPFJ@204441|Rhodospirillales 204441|Rhodospirillales S peptidase U62, modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD k141_6308_1 572477.Alvin_1323 2.85e-77 244.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim k141_2147_2 1288298.rosmuc_00091 7.07e-69 212.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,2U7ND@28211|Alphaproteobacteria,46Q3Q@74030|Roseovarius 28211|Alphaproteobacteria K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 k141_9121_1 207954.MED92_11444 2.77e-83 261.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XICX@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_9121_2 991905.SL003B_0415 7.55e-97 293.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TTN2@28211|Alphaproteobacteria,4BPDY@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component urtC - - ko:K11961 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 k141_14011_1 1502850.FG91_01876 1e-72 238.0 COG2850@1|root,COG2850@2|Bacteria,1RDTN@1224|Proteobacteria,2U8MT@28211|Alphaproteobacteria,2K4YG@204457|Sphingomonadales 204457|Sphingomonadales S Cupin superfamily protein - - - - - - - - - - - - Cupin_8 k141_21020_1 357804.Ping_2914 4.27e-29 110.0 2BV15@1|root,32QDR@2|Bacteria,1RJ98@1224|Proteobacteria,1RYP4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB k141_18886_1 521674.Plim_1432 2.68e-30 115.0 COG1678@1|root,COG1678@2|Bacteria,2J0F0@203682|Planctomycetes 203682|Planctomycetes K Transcriptional regulator - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_15421_1 391626.OAN307_c07510 2.8e-67 216.0 COG3279@1|root,COG3300@1|root,COG3279@2|Bacteria,COG3300@2|Bacteria,1PXIQ@1224|Proteobacteria,2TT3B@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Carbon monoxide dehydrogenase operon C protein coxC GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K21696 - - - - ko00000,ko03000 - - - LytTR,MHYT k141_19582_1 1196095.GAPWK_2727 5.75e-98 297.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM k141_20298_1 1313301.AUGC01000004_gene2355 5e-82 261.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N k141_5662_1 1122137.AQXF01000005_gene1229 6.87e-33 119.0 COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,2UCZN@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Putative thioesterase (yiiD_Cterm) - - - - - - - - - - - - YiiD_C k141_5662_2 1279017.AQYJ01000027_gene1778 2.84e-08 54.3 COG4591@1|root,COG4591@2|Bacteria,1QVRH@1224|Proteobacteria,1T2I0@1236|Gammaproteobacteria,4668Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_4233_1 666681.M301_0483 0.000418 49.7 COG4191@1|root,COG4585@1|root,COG4191@2|Bacteria,COG4585@2|Bacteria,1N1PW@1224|Proteobacteria,2VU49@28216|Betaproteobacteria 28216|Betaproteobacteria T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - HATPase_c,HisKA_3 k141_3547_1 713587.THITH_02640 4.88e-138 403.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG k141_17463_1 1082705.JIBP01000017_gene547 1.6e-08 58.5 COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria 1224|Proteobacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins gspM GO:0008150,GO:0009405,GO:0044419,GO:0051704 - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM k141_17463_2 519989.ECTPHS_04299 1.66e-26 117.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1X1FM@135613|Chromatiales 135613|Chromatiales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_9813_1 589865.DaAHT2_0170 4.01e-23 101.0 2DKFZ@1|root,309D6@2|Bacteria,1QZK6@1224|Proteobacteria,43CQP@68525|delta/epsilon subdivisions,2X7Y5@28221|Deltaproteobacteria,2MPAB@213118|Desulfobacterales 28221|Deltaproteobacteria S Domain of unknown function (DUF4382) - - - - - - - - - - - - CarboxypepD_reg,DUF4382 k141_756_1 1288826.MSNKSG1_06138 2.17e-189 532.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RSCK@1236|Gammaproteobacteria,463XY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Saccharopine dehydrogenase lys - - - - - - - - - - - Sacchrp_dh_NADP k141_756_2 1288826.MSNKSG1_06133 0.0 973.0 COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,466X9@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components cydC GO:0000101,GO:0003333,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006857,GO:0006865,GO:0008150,GO:0009889,GO:0015399,GO:0015405,GO:0015711,GO:0015804,GO:0015833,GO:0015849,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0032973,GO:0032991,GO:0033228,GO:0034220,GO:0034635,GO:0034775,GO:0035443,GO:0035672,GO:0042623,GO:0042626,GO:0042883,GO:0042886,GO:0042939,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051181,GO:0051193,GO:0051234,GO:0055085,GO:0065007,GO:0070453,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0098533,GO:0098655,GO:0098656,GO:0098796,GO:0098797,GO:0140115,GO:1901401,GO:1901463,GO:1902494,GO:1902495,GO:1903712,GO:1903825,GO:1904949,GO:1905039,GO:1990351 - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - iEC55989_1330.EC55989_0931,iECIAI1_1343.ECIAI1_0926,iECO103_1326.ECO103_0929,iECO111_1330.ECO111_0954,iECSE_1348.ECSE_0944,iECW_1372.ECW_m0996,iEKO11_1354.EKO11_2951,iSDY_1059.SDY_2375,iWFL_1372.ECW_m0996 ABC_membrane,ABC_tran k141_756_3 1288826.MSNKSG1_06128 1.18e-34 130.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,465RH@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k141_11259_1 1278309.KB907109_gene3296 5.68e-115 335.0 COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,1RNFR@1236|Gammaproteobacteria,1XH35@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - ko:K02521 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_11259_2 1278309.KB907109_gene3295 6.01e-144 412.0 COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,1S2RI@1236|Gammaproteobacteria,1XJPS@135619|Oceanospirillales 135619|Oceanospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_5663_1 314262.MED193_14697 1.74e-38 145.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2P1XD@2433|Roseobacter 28211|Alphaproteobacteria D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k141_18183_1 1163617.SCD_n02272 2.08e-14 72.8 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKVT@28216|Betaproteobacteria 28216|Betaproteobacteria I PFAM membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k141_18183_2 317025.Tcr_1610 1.15e-60 198.0 COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,1S74G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_1459_1 1288826.MSNKSG1_17051 1.66e-102 303.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1RDY0@1224|Proteobacteria,1SYCB@1236|Gammaproteobacteria,46CWP@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases ascD - 1.16.1.3,1.17.1.1,1.5.1.41 ko:K00523,ko:K05368 ko00520,ko00740,ko00860,ko01100,map00520,map00740,map00860,map01100 - R00097,R03391,R03392,R05705 RC00126,RC00220,RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_1459_2 1288826.MSNKSG1_17056 1.31e-278 763.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,46647@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_2 k141_21655_2 1121935.AQXX01000085_gene5321 5.22e-80 237.0 COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,1S686@1236|Gammaproteobacteria,1XKRD@135619|Oceanospirillales 135619|Oceanospirillales S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 k141_21655_4 1278309.KB907100_gene2261 4.39e-113 346.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XH31@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C k141_3548_1 1121373.KB903665_gene3110 7.35e-41 153.0 COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia 976|Bacteroidetes S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin k141_4234_1 472759.Nhal_2781 1.29e-06 48.9 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_4234_2 472759.Nhal_2780 1.34e-56 186.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RWHU@1236|Gammaproteobacteria,1WYF3@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161,ko:K00162,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k141_9814_1 87626.PTD2_07294 0.000527 45.8 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,2Q5GQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS_9,Response_reg,dCache_1 k141_21021_1 1232410.KI421421_gene3529 2.31e-67 238.0 COG2067@1|root,COG2885@1|root,COG2067@2|Bacteria,COG2885@2|Bacteria,1MY5K@1224|Proteobacteria 1224|Proteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - DUF11 k141_11928_1 1288826.MSNKSG1_00586 4.07e-149 423.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1S61M@1236|Gammaproteobacteria,467SZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k141_11928_2 1288826.MSNKSG1_00591 4.04e-91 268.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,466HW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k141_11928_3 1288826.MSNKSG1_00596 5.88e-25 102.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,4657V@72275|Alteromonadaceae 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_16793_1 1278309.KB907099_gene3021 1.79e-88 263.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1XJVW@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF924 k141_16793_2 1278309.KB907099_gene3022 1.18e-132 386.0 COG2199@1|root,COG3706@2|Bacteria,1N9K1@1224|Proteobacteria,1SCWP@1236|Gammaproteobacteria,1XMHY@135619|Oceanospirillales 135619|Oceanospirillales T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF k141_16793_3 713586.KB900536_gene156 1.35e-37 140.0 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity ugpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k141_16793_4 1278309.KB907099_gene3023 1.62e-84 264.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XHG3@135619|Oceanospirillales 135619|Oceanospirillales F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N k141_9122_1 267608.RSp1219 1.76e-84 278.0 COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,1KG4U@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasA - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_5664_1 1417296.U879_20045 2.42e-69 219.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_11260_1 765911.Thivi_0551 1.25e-38 141.0 COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales 135613|Chromatiales C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_17,Fer4_8 k141_11260_2 292415.Tbd_2479 4.2e-69 216.0 COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria 28216|Betaproteobacteria C Nitrate reductase gamma subunit - - - - - - - - - - - - Nitrate_red_gam k141_14012_1 1278309.KB907099_gene3062 2.25e-58 188.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,1SYK4@1236|Gammaproteobacteria,1XJ2X@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_14012_2 1278309.KB907099_gene3063 2.41e-167 472.0 COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,1SYJD@1236|Gammaproteobacteria,1XHTG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k141_17464_1 32042.PstZobell_14066 2.4e-26 106.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1Z0IP@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE k141_17464_2 85643.Tmz1t_0537 5.63e-91 271.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,2KUKC@206389|Rhodocyclales 206389|Rhodocyclales P COG4149 ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 k141_14722_1 631362.Thi970DRAFT_04271 3.42e-90 281.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales 135613|Chromatiales O PFAM Magnesium chelatase, ChlI subunit - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k141_15422_1 1278309.KB907100_gene2224 2.34e-157 459.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1XHT6@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_15422_2 748247.AZKH_p0314 1.49e-41 153.0 COG1018@1|root,COG3182@1|root,COG1018@2|Bacteria,COG3182@2|Bacteria,1MU6E@1224|Proteobacteria,2VK6Y@28216|Betaproteobacteria,2KXZ4@206389|Rhodocyclales 206389|Rhodocyclales C (sprot VANB_PSEUH). The vanillate demethylase (EC 1.14.13.82) consists of two proteins an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin - - - ko:K03863 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001 - - - Fer2 k141_12624_1 1122599.AUGR01000014_gene588 7.15e-40 142.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1XN2Q@135619|Oceanospirillales 135619|Oceanospirillales C 4Fe-4S binding domain - - - - - - - - - - - - CCG,Fer4_8 k141_12624_2 1122599.AUGR01000014_gene589 5.6e-173 492.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,1XHN3@135619|Oceanospirillales 135619|Oceanospirillales C FAD binding domain glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 k141_3549_1 379731.PST_1281 6.41e-89 275.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1Z0AN@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C Cytochrome bd-type quinol oxidase, subunit 1 cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iPC815.YPO1117,iSFxv_1172.SFxv_0621,iS_1188.S0577 Cyt_bd_oxida_I k141_56_1 1288826.MSNKSG1_14177 7.5e-96 286.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k141_56_2 1288826.MSNKSG1_14172 0.0 951.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,464HZ@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_20299_1 1109445.AGSX01000043_gene292 8.38e-37 153.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1Z18Z@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_9815_1 1122197.ATWI01000011_gene442 2.5e-62 199.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k141_9815_2 1122197.ATWI01000011_gene443 2.69e-28 113.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_2148_1 1278309.KB907099_gene2737 3.24e-316 890.0 COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,1XH4U@135619|Oceanospirillales 135619|Oceanospirillales T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg k141_21022_1 187272.Mlg_1350 2.19e-71 224.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales 135613|Chromatiales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ k141_7750_1 177437.HRM2_18130 2.02e-30 115.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MJ8C@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k141_7750_2 314231.FP2506_02405 4.44e-18 94.0 COG3307@1|root,COG3307@2|Bacteria,1NI7K@1224|Proteobacteria,2USRW@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG3307 Lipid A core - O-antigen ligase - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C k141_17465_1 572477.Alvin_2756 2.13e-12 66.2 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase k141_17465_2 78398.KS43_16715 8.58e-42 145.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1MPV5@122277|Pectobacterium 1236|Gammaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_00132,iE2348C_1286.E2348C_0137,iECBD_1354.ECBD_3485,iECB_1328.ECB_00133,iECD_1391.ECD_00133,iPC815.YPO3401 Pantoate_transf k141_16794_1 1278309.KB907104_gene838 2.39e-90 302.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria KLT Serine threonine protein kinase stk1 - 2.7.11.1 ko:K08282,ko:K11916,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02044 - - - FGE-sulfatase,Pkinase k141_3715_1 1121403.AUCV01000007_gene1200 4.46e-52 187.0 COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,42ZP1@68525|delta/epsilon subdivisions 1224|Proteobacteria M Glycosyl transferase family group 2 alg8 - 2.4.1.33 ko:K19290 ko00051,map00051 - R08692 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.7,4.D.1.1.9 GT2 - Glyco_tranf_2_3 k141_14168_1 83406.HDN1F_02170 5.58e-106 316.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1J57X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k141_7178_1 697282.Mettu_3162 6.26e-66 230.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_13468_1 765912.Thimo_0823 5.19e-207 584.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWGD@135613|Chromatiales 135613|Chromatiales T response regulator - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k141_13468_2 1122927.KB895414_gene5239 4.43e-07 52.4 COG2199@1|root,COG4191@1|root,COG2199@2|Bacteria,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4IUTK@91061|Bacilli 91061|Bacilli T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF,HATPase_c,HisKA k141_11399_1 754476.Q7A_247 9.93e-90 275.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,46093@72273|Thiotrichales 72273|Thiotrichales LU TIGRFAM DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A k141_11399_2 396588.Tgr7_0192 3.79e-62 195.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales 135613|Chromatiales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 k141_11399_3 948565.AFFP02000001_gene1083 0.000674 42.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1Y70A@135625|Pasteurellales 135625|Pasteurellales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom k141_200_1 1288826.MSNKSG1_05311 7.92e-114 331.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,466F8@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG3001 Fructosamine-3-kinase yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - - - - - - - - - - Fructosamin_kin k141_200_2 1288826.MSNKSG1_05306 3.46e-61 187.0 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,468VX@72275|Alteromonadaceae 1236|Gammaproteobacteria C acylphosphatase activity acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Acylphosphatase k141_200_3 714943.Mucpa_1298 1.98e-07 54.3 COG1961@1|root,COG1961@2|Bacteria,4NHW0@976|Bacteroidetes,1IR5S@117747|Sphingobacteriia 976|Bacteroidetes L Recombinase - - - - - - - - - - - - Recombinase,Resolvase k141_200_4 1288826.MSNKSG1_05296 6.22e-24 94.4 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S8Q5@1236|Gammaproteobacteria,46DGH@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG1335 Amidases related to nicotinamidase - - - - - - - - - - - - Isochorismatase k141_18350_1 1125863.JAFN01000001_gene187 5.25e-17 85.9 COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - ABC_sub_bind,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_18350_2 722419.PH505_am00440 2.1e-137 405.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2Q02V@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains fleR - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_3017_1 1121405.dsmv_1524 2.16e-23 93.6 COG4392@1|root,COG4392@2|Bacteria,1NAPF@1224|Proteobacteria,432FK@68525|delta/epsilon subdivisions,2WXDN@28221|Deltaproteobacteria,2MME1@213118|Desulfobacterales 28221|Deltaproteobacteria S Branched-chain amino acid transport protein (AzlD) - - - - - - - - - - - - AzlD k141_3017_2 1278309.KB907099_gene2823 1.39e-142 406.0 COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1RZYJ@1236|Gammaproteobacteria,1XQXV@135619|Oceanospirillales 135619|Oceanospirillales E AzlC family - - - - - - - - - - - - AzlC k141_3017_3 1278309.KB907099_gene2822 4.82e-107 317.0 COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1Q5AK@1224|Proteobacteria,1S19Z@1236|Gammaproteobacteria,1XK64@135619|Oceanospirillales 135619|Oceanospirillales K MarR family - - - - - - - - - - - - Acetyltransf_1,MarR,MarR_2 k141_10703_1 396588.Tgr7_2153 2.56e-150 436.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k141_12082_1 1535422.ND16A_3953 1.87e-12 64.7 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator cymR - - - - - - - - - - - Rrf2 k141_12789_1 395493.BegalDRAFT_3276 1.45e-45 155.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,460S6@72273|Thiotrichales 72273|Thiotrichales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k141_12789_2 2340.JV46_27640 1.09e-21 92.8 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1J4F2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k141_21825_1 626887.J057_02570 2.57e-54 181.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,4652T@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1230 Co Zn Cd efflux system component - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_19718_1 452637.Oter_2222 1.85e-36 134.0 COG1566@1|root,COG1566@2|Bacteria,46V91@74201|Verrucomicrobia,3K8CS@414999|Opitutae 414999|Opitutae V HlyD family secretion protein - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_19718_2 555778.Hneap_0659 6.43e-25 103.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,1WXYC@135613|Chromatiales 135613|Chromatiales EGP Major Facilitator Superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k141_17655_1 398580.Dshi_1652 3.74e-108 323.0 COG1653@1|root,COG1653@2|Bacteria,1MXZJ@1224|Proteobacteria,2TSFY@28211|Alphaproteobacteria 28211|Alphaproteobacteria G ABC-type sugar transport system periplasmic component aglE - - ko:K10232 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - SBP_bac_1,SBP_bac_8 k141_8589_1 870187.Thini_2499 6.81e-122 373.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales 72273|Thiotrichales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_20474_1 493475.GARC_1392 1.13e-10 72.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_6468_1 1049564.TevJSym_ak00380 2.43e-202 578.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1J572@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Oligopeptidase A prlC GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_6468_2 1292035.H476_1502 1.69e-05 49.7 COG3584@1|root,COG3807@1|root,COG3584@2|Bacteria,COG3807@2|Bacteria,1TTIK@1239|Firmicutes,2493P@186801|Clostridia,25T9G@186804|Peptostreptococcaceae 186801|Clostridia T 3D domain - - - - - - - - - - - - 3D,SH3_3 k141_16940_1 748247.AZKH_4193 3.19e-42 159.0 COG0840@1|root,COG0840@2|Bacteria,1NCMF@1224|Proteobacteria,2VJC0@28216|Betaproteobacteria,2KW4V@206389|Rhodocyclales 206389|Rhodocyclales NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_9239_1 398767.Glov_1886 0.000956 48.1 COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,1R5RG@1224|Proteobacteria,42NHW@68525|delta/epsilon subdivisions,2WKI8@28221|Deltaproteobacteria,43TKH@69541|Desulfuromonadales 28221|Deltaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Trm112p k141_9239_2 1156937.MFUM_810052 2e-08 62.0 COG0500@1|root,COG2226@2|Bacteria,46WVS@74201|Verrucomicrobia,37GFF@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 k141_12083_1 1121943.KB899998_gene1563 2.07e-41 155.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XHV8@135619|Oceanospirillales 135619|Oceanospirillales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_201_1 1202962.KB907154_gene771 2.67e-07 56.2 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains luxO - - ko:K10912 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_201_2 29486.NJ56_03030 1.56e-16 79.3 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,41FAP@629|Yersinia 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA GO:0003674,GO:0005215,GO:0005451,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006875,GO:0006883,GO:0006885,GO:0006950,GO:0006970,GO:0008150,GO:0008289,GO:0008324,GO:0009628,GO:0009651,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0042592,GO:0043157,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0055065,GO:0055067,GO:0055078,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1901611,GO:1901612,GO:1902600 - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - iSF_1195.SF0016,iSFxv_1172.SFxv_0017,iS_1188.S0018 Na_H_antiport_1 k141_8590_1 666685.R2APBS1_0347 1.29e-80 255.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1X3SN@135614|Xanthomonadales 135614|Xanthomonadales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groEL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_1621_1 391593.RCCS2_11954 8.1e-61 190.0 COG1522@1|root,COG1522@2|Bacteria,1RI7R@1224|Proteobacteria,2U9CC@28211|Alphaproteobacteria,2P2V8@2433|Roseobacter 28211|Alphaproteobacteria K Transcriptional Regulator, AsnC family aldR - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 k141_14877_1 870187.Thini_1080 2.72e-42 146.0 COG0730@1|root,COG0730@2|Bacteria,1MY0T@1224|Proteobacteria,1RS7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_14877_2 1485544.JQKP01000003_gene122 2.28e-57 178.0 COG2920@1|root,COG2920@2|Bacteria,1RITK@1224|Proteobacteria,2W32H@28216|Betaproteobacteria,44WIY@713636|Nitrosomonadales 28216|Betaproteobacteria P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_14877_3 7739.XP_002600896.1 0.000291 44.3 COG2110@1|root,KOG2633@2759|Eukaryota,39CUN@33154|Opisthokonta,3BE16@33208|Metazoa,3CTKM@33213|Bilateria,48463@7711|Chordata 33208|Metazoa BK positive regulation of interleukin-4-mediated signaling pathway PARP14 GO:0000166,GO:0001932,GO:0001933,GO:0001934,GO:0001959,GO:0001960,GO:0001961,GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006471,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010468,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0016740,GO:0016757,GO:0016763,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0023057,GO:0031323,GO:0031324,GO:0031325,GO:0031347,GO:0031348,GO:0031399,GO:0031400,GO:0031401,GO:0032268,GO:0032269,GO:0032270,GO:0036094,GO:0036211,GO:0042325,GO:0042326,GO:0042327,GO:0042509,GO:0042531,GO:0042532,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045824,GO:0045936,GO:0045937,GO:0046425,GO:0046426,GO:0046427,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050662,GO:0050730,GO:0050731,GO:0050732,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051248,GO:0051287,GO:0060255,GO:0060330,GO:0060331,GO:0060334,GO:0060336,GO:0060759,GO:0060760,GO:0060761,GO:0065007,GO:0070212,GO:0070403,GO:0071704,GO:0080090,GO:0080134,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1902214,GO:1902216,GO:1902531,GO:1902532,GO:1902533,GO:1904892,GO:1904893,GO:1904894 2.4.2.30 ko:K05747,ko:K15261 ko04062,ko04144,ko04520,ko04530,ko04666,ko04810,ko05100,ko05130,ko05131,ko05132,ko05231,map04062,map04144,map04520,map04530,map04666,map04810,map05100,map05130,map05131,map05132,map05231 - - - ko00000,ko00001,ko01000,ko04131,ko04812 - - - Macro,PARP,WWE k141_10704_1 977880.RALTA_B0267 3.63e-30 117.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,1K33W@119060|Burkholderiaceae 28216|Betaproteobacteria C Isocitrate lyase - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k141_19075_1 1122599.AUGR01000009_gene2437 5.09e-166 469.0 COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,1RSBY@1236|Gammaproteobacteria,1XHRB@135619|Oceanospirillales 135619|Oceanospirillales Q Phytanoyl-CoA dioxygenase (PhyH) ectD - 1.14.11.55 ko:K10674 ko00260,ko01120,map00260,map01120 - R08050 RC00661 ko00000,ko00001,ko01000 - - - PhyH k141_19075_2 377629.TERTU_3380 1.43e-77 232.0 COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,1S41A@1236|Gammaproteobacteria,2PNK6@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Ectoine synthase ectC - 4.2.1.108 ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06979 RC01729 ko00000,ko00001,ko00002,ko01000 - - - Ectoine_synth k141_19075_3 1278309.KB907099_gene2788 4.88e-283 777.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1XHNN@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family ectB - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k141_19075_4 1056512.D515_01026 1.53e-25 101.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,1XVUK@135623|Vibrionales 135623|Vibrionales K L-2,4-diaminobutyric acid acetyltransferase ectA GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 k141_3716_2 1127673.GLIP_2928 4.65e-27 119.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_14170_2 1123261.AXDW01000004_gene2857 4.33e-17 81.3 COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1T8T9@1236|Gammaproteobacteria,1X7ZW@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretion system (T2SS), protein M - - - - - - - - - - - - T2SSM k141_7905_1 1201293.AKXQ01000018_gene2746 1.5e-28 118.0 COG1018@1|root,COG3217@1|root,COG1018@2|Bacteria,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Mosc domain protein beta barrel domain protein ycbX GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - ko:K07140 - - - - ko00000 - - - FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1 k141_3019_1 329726.AM1_5439 8.61e-55 174.0 COG3791@1|root,COG3791@2|Bacteria,1G5S8@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA k141_3019_2 1298593.TOL_2835 5.37e-16 78.6 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S10P@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_202_1 935567.JAES01000001_gene2175 1.12e-60 197.0 COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,1S5SD@1236|Gammaproteobacteria,1X617@135614|Xanthomonadales 135614|Xanthomonadales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k141_21193_1 555778.Hneap_0780 3.3e-86 267.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXYB@135613|Chromatiales 135613|Chromatiales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_21193_2 269796.Rru_A2913 8.47e-81 246.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,2JQ2Y@204441|Rhodospirillales 204441|Rhodospirillales T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C k141_6469_1 388401.RB2150_03279 4.68e-103 321.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3ZG8F@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C Malic enzyme dme GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic k141_7180_1 349521.HCH_00575 7.14e-98 293.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1XI5W@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 k141_7180_2 395493.BegalDRAFT_2669 3.54e-34 132.0 COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,1NEBU@1224|Proteobacteria,1RYA6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T response regulator - - - - - - - - - - - - Response_reg k141_19719_1 595537.Varpa_4424 4.05e-125 366.0 COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,4ACT9@80864|Comamonadaceae 28216|Betaproteobacteria M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_4420_1 1288826.MSNKSG1_18195 5.2e-90 285.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k141_4420_2 1288826.MSNKSG1_18200 3.3e-204 566.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,4645H@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator metR - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_11401_1 765913.ThidrDRAFT_4145 8.15e-150 452.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWAU@135613|Chromatiales 135613|Chromatiales U Hydrophobe Amphiphile Efflux-1 (HAE1) - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k141_21828_2 1123401.JHYQ01000015_gene1412 1.56e-44 148.0 2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,1S97C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10705_1 1288826.MSNKSG1_03385 5.27e-84 265.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,46481@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the glutamate synthase family gltB - - - - - - - - - - - Glu_synthase k141_906_1 1288826.MSNKSG1_12462 7.54e-199 559.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_906_2 1288826.MSNKSG1_12467 0.0 1521.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,463Z7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k141_906_3 1288826.MSNKSG1_12472 1.43e-247 680.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,466NT@72275|Alteromonadaceae 1236|Gammaproteobacteria S phosphotransferase related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH k141_906_4 1288826.MSNKSG1_12477 1.32e-150 424.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,466S9@72275|Alteromonadaceae 1236|Gammaproteobacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_9951_2 247639.MGP2080_00290 9.26e-35 134.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k141_16970_1 1297742.A176_01680 8.51e-28 122.0 COG0727@1|root,COG0727@2|Bacteria,1N9E6@1224|Proteobacteria,438VA@68525|delta/epsilon subdivisions,2X2J7@28221|Deltaproteobacteria,2YXW8@29|Myxococcales 28221|Deltaproteobacteria S PFAM Uncharacterised protein family (UPF0153) - - - ko:K18475 - - - - ko00000,ko01000,ko02035 - - - CxxCxxCC k141_10723_1 247633.GP2143_02214 6.95e-60 196.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1J4YQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase dapC - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_9266_1 1120953.AUBH01000008_gene311 3.72e-37 138.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,4640Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL k141_9266_2 93220.LV28_11260 7.9e-27 102.0 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria,1K734@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - DUF1269 k141_11418_1 933262.AXAM01000016_gene149 1.95e-59 202.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales 28221|Deltaproteobacteria M TIGRFAM penicillin-binding protein, 1A family mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iAF987.Gmet_0354 PCB_OB,Transgly,Transpeptidase k141_18373_1 367336.OM2255_09121 4.21e-62 195.0 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,2TUK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S hydrolases of HD superfamily MA20_42120 - - ko:K06952 - - - - ko00000 - - - HD,HD_3 k141_3042_1 693444.D782_1121 1.95e-08 56.6 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains yfhA GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_3042_2 388051.AUFE01000012_gene2825 4.59e-08 57.8 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2WGJC@28216|Betaproteobacteria,1K4DX@119060|Burkholderiaceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA k141_923_1 1144275.COCOR_07191 2.91e-39 142.0 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QY0@68525|delta/epsilon subdivisions,2WMTP@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_3745_1 1500894.JQNN01000001_gene2617 2.25e-62 212.0 COG0303@1|root,COG0746@1|root,COG0303@2|Bacteria,COG0746@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,473QZ@75682|Oxalobacteraceae 28216|Betaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor moeA2 - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k141_4449_1 225937.HP15_2386 1.22e-123 362.0 COG0451@1|root,COG0451@2|Bacteria,1NXWA@1224|Proteobacteria,1RZWF@1236|Gammaproteobacteria,4646D@72275|Alteromonadaceae 1236|Gammaproteobacteria GM Vitamin K epoxide reductase family - - - - - - - - - - - - Epimerase,SPW,VKOR k141_4449_2 225937.HP15_2385 3.17e-235 652.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,464FW@72275|Alteromonadaceae 1236|Gammaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd GO:0000271,GO:0003674,GO:0003824,GO:0003979,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_2287 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k141_4449_3 225937.HP15_2384 4.62e-76 230.0 COG2148@1|root,COG2148@2|Bacteria,1R4J5@1224|Proteobacteria,1RP9R@1236|Gammaproteobacteria,466P1@72275|Alteromonadaceae 1236|Gammaproteobacteria M Bacterial sugar transferase wbfU - - - - - - - - - - - Bac_transf k141_9952_1 392500.Swoo_1484 1.69e-55 181.0 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,2Q9MA@267890|Shewanellaceae 1236|Gammaproteobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp k141_17679_1 1122137.AQXF01000012_gene3453 4.61e-41 135.0 2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,2UG09@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_13488_1 1288826.MSNKSG1_04431 0.0 1117.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0405 Gamma-glutamyltransferase ggt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706 G_glu_transpept k141_13488_2 1288826.MSNKSG1_04426 6.13e-55 171.0 COG0011@1|root,COG0011@2|Bacteria,1N8R0@1224|Proteobacteria,1SCF3@1236|Gammaproteobacteria,4690Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S YKOF-related Family - - - - - - - - - - - - Thiamine_BP,Ykof k141_13488_3 1288826.MSNKSG1_04421 0.0 1224.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RR0R@1236|Gammaproteobacteria,469YC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 k141_4559_1 1288826.MSNKSG1_02173 4.76e-84 263.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,465RZ@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II acs - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_4559_2 1288826.MSNKSG1_02178 7.3e-131 372.0 COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,1RZGS@1236|Gammaproteobacteria,46AH7@72275|Alteromonadaceae 1236|Gammaproteobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k141_4559_3 1288826.MSNKSG1_02183 2.92e-135 387.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,4641B@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0119 Isopropylmalate homocitrate citramalate synthases mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like k141_17065_1 1122201.AUAZ01000018_gene1681 3.93e-65 217.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,463YC@72275|Alteromonadaceae 1236|Gammaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Anticodon_1,tRNA-synt_1g,tRNA_bind k141_12225_1 1288826.MSNKSG1_08503 5.19e-155 446.0 COG1028@1|root,COG1028@2|Bacteria,1MXRY@1224|Proteobacteria,1RZMB@1236|Gammaproteobacteria,46CH9@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k141_21302_1 1127673.GLIP_2928 3.4e-68 236.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_5210_1 1121921.KB898711_gene1998 4.09e-51 174.0 COG0421@1|root,COG0421@2|Bacteria,1QWZZ@1224|Proteobacteria,1T31M@1236|Gammaproteobacteria,2PNTX@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Methyltransf_25 k141_19848_1 1255043.TVNIR_0868 1.55e-43 150.0 28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,1RS8I@1236|Gammaproteobacteria,1WWZ9@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_19848_2 870187.Thini_1163 1.82e-118 353.0 2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18456_1 1049564.TevJSym_aa02480 6.35e-31 117.0 COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,1RRQ6@1236|Gammaproteobacteria,1J7WK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k141_14272_1 28229.ND2E_1968 1.12e-14 73.9 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,2Q79R@267889|Colwelliaceae 1236|Gammaproteobacteria S MMPL family VP1286 - - ko:K07003 - - - - ko00000 - - - MMPL k141_14272_2 1328313.DS2_08555 8.03e-42 150.0 COG1309@1|root,COG1309@2|Bacteria,1RA1I@1224|Proteobacteria,1S35J@1236|Gammaproteobacteria,46BVU@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N k141_365_1 754476.Q7A_2795 9.64e-122 356.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,461ZY@72273|Thiotrichales 72273|Thiotrichales P TIGRFAM cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux k141_365_2 1198232.CYCME_1695 2.46e-309 872.0 28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,1RN0X@1236|Gammaproteobacteria,461PJ@72273|Thiotrichales 72273|Thiotrichales M Fatty acid cis/trans isomerase (CTI) - - - - - - - - - - - - CTI k141_19219_1 1042377.AFPJ01000051_gene35 2.88e-50 175.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_10085_1 90813.JQMT01000001_gene1820 2.58e-78 251.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,463SJ@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp k141_10085_2 265072.Mfla_2576 1.91e-21 92.8 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KNA6@206350|Nitrosomonadales 206350|Nitrosomonadales EG EamA-like transporter family - - - - - - - - - - - - EamA k141_3179_1 396588.Tgr7_0300 7.51e-91 286.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept k141_1050_1 1288826.MSNKSG1_11488 2.94e-36 132.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,469E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycolate oxidase iron-sulfur subunit glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 k141_3838_7 1278309.KB907099_gene3071 9.81e-189 533.0 COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,1XS4E@135619|Oceanospirillales 135619|Oceanospirillales E Amino Acid - - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k141_18466_1 94122.Shewana3_3543 4.44e-16 80.5 COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9 k141_6593_1 1198232.CYCME_0604 1.21e-25 107.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,45ZS2@72273|Thiotrichales 72273|Thiotrichales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin,Thioredoxin_7 k141_6593_2 880073.Calab_1229 1.32e-27 109.0 COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria 2|Bacteria O Thioredoxin-like resA - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Thioredoxin_8 k141_20618_1 1040989.AWZU01000008_gene3666 6.74e-23 98.2 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TPR_19,Trans_reg_C k141_1780_2 1166948.JPZL01000001_gene2547 8.74e-109 327.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XIU2@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_1780_3 1049564.TevJSym_bp00040 4.03e-109 319.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1J5QX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Phosphoserine phosphatase - - - - - - - - - - - - HAD k141_3199_1 999141.GME_07449 4.31e-50 180.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XHUD@135619|Oceanospirillales 135619|Oceanospirillales L Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k141_12937_1 1163407.UU7_11864 1.31e-73 244.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k141_12937_2 1046724.KB889876_gene333 2.22e-105 313.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,464SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k141_17807_1 1278309.KB907106_gene1259 9.16e-232 668.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,1XKKF@135619|Oceanospirillales 135619|Oceanospirillales M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_17807_2 1278309.KB907106_gene1260 1.08e-214 619.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XHVX@135619|Oceanospirillales 135619|Oceanospirillales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_8716_1 207954.MED92_04914 1.54e-46 154.0 29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,1S4I9@1236|Gammaproteobacteria,1XJQY@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8716_2 1278309.KB907106_gene1247 1.03e-290 799.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XH3S@135619|Oceanospirillales 135619|Oceanospirillales G TRAP C4-dicarboxylate transport system permease DctM subunit - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM k141_8716_3 207954.MED92_04929 5.57e-101 296.0 COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,1RZ8E@1236|Gammaproteobacteria,1XIKV@135619|Oceanospirillales 135619|Oceanospirillales G PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ k141_21319_2 1286106.MPL1_03353 7.08e-14 70.5 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,45ZQH@72273|Thiotrichales 72273|Thiotrichales E peptidase - - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 k141_12243_1 111781.Lepto7376_2763 8.13e-38 135.0 COG1216@1|root,COG1216@2|Bacteria,1G2TX@1117|Cyanobacteria,1H9Y9@1150|Oscillatoriales 1117|Cyanobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - - k141_11525_1 713587.THITH_06425 1.07e-08 56.2 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C k141_11525_2 870187.Thini_4125 7.57e-139 400.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales 72273|Thiotrichales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_11525_3 1123228.AUIH01000006_gene2220 1.47e-09 55.1 COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,1XMQT@135619|Oceanospirillales 135619|Oceanospirillales O Cbb3-type cytochrome oxidase component FixQ ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_11525_4 870187.Thini_4123 1.63e-114 332.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM cytochrome c oxidase, cbb3-type, subunit II - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO k141_21990_1 1288826.MSNKSG1_08273 1.53e-23 99.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,465TJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_21990_2 930166.CD58_08400 1.37e-51 171.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria N this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine motC - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_5933_1 1288826.MSNKSG1_09958 3.98e-71 219.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc k141_5933_2 1288826.MSNKSG1_09963 4.43e-49 156.0 2E5ME@1|root,330CB@2|Bacteria,1N8G6@1224|Proteobacteria,1SC9I@1236|Gammaproteobacteria,468TX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phosphate-starvation-inducible E IV02_05780 - - - - - - - - - - - PsiE k141_5933_3 1288826.MSNKSG1_09968 1.68e-297 815.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF k141_5933_4 1288826.MSNKSG1_09973 5.35e-145 410.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,46768@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - DUF4124,SLT k141_5933_5 1288826.MSNKSG1_09978 1.18e-302 857.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,463XX@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_12938_1 177437.HRM2_25270 1.13e-80 243.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42P3W@68525|delta/epsilon subdivisions,2WNCT@28221|Deltaproteobacteria,2MHNB@213118|Desulfobacterales 28221|Deltaproteobacteria M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k141_6594_1 375451.RD1_0403 1.12e-29 111.0 COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,2U77W@28211|Alphaproteobacteria,2P2VK@2433|Roseobacter 28211|Alphaproteobacteria S protein with SCP PR1 domains - - - - - - - - - - - - CAP k141_13607_1 314345.SPV1_03478 3.45e-105 310.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase type 11 arsM - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 k141_13607_2 377629.TERTU_2737 8.36e-51 166.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,2PNJJ@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Putative zinc- or iron-chelating domain ycgN - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_13607_3 745411.B3C1_16445 1.34e-13 70.5 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1J5VV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction histidine kinase phoQ - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,PhoQ_Sensor k141_19865_1 2340.JV46_24290 2.21e-134 391.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1J9VF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Hydrogenase formation hypA family hypD GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - ko:K04654 - - - - ko00000 - - - HypD k141_9375_1 1288826.MSNKSG1_04376 7.31e-54 171.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,468EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_9375_2 1288826.MSNKSG1_04371 2.42e-70 213.0 28WMF@1|root,2ZIMA@2|Bacteria,1PB4R@1224|Proteobacteria,1STAY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_9375_3 1288826.MSNKSG1_04366 8.89e-59 181.0 2E53A@1|root,32ZWE@2|Bacteria,1N77T@1224|Proteobacteria,1SA8T@1236|Gammaproteobacteria,46B9B@72275|Alteromonadaceae 1236|Gammaproteobacteria S YrhK-like protein - - - - - - - - - - - - YrhK k141_9375_4 1288826.MSNKSG1_04361 1.71e-74 223.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,467XF@72275|Alteromonadaceae 1236|Gammaproteobacteria H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a k141_9375_5 1288826.MSNKSG1_04356 1.06e-162 455.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,467W8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K13053,ko:K14160 - - - - ko00000,ko03036,ko03400 - - - RecA,SulA k141_9375_6 1288826.MSNKSG1_04351 0.0 914.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,465IA@72275|Alteromonadaceae 1236|Gammaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS k141_9375_7 1288826.MSNKSG1_04346 0.0 1295.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,464B5@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k141_11526_1 572477.Alvin_2221 1.86e-40 148.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales 135613|Chromatiales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_11526_2 377629.TERTU_1962 5.75e-45 147.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,2PNP2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S ATP-dependent Clp protease adaptor protein ClpS clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k141_8106_1 270374.MELB17_14281 5.08e-228 657.0 COG3533@1|root,COG3533@2|Bacteria,1QXFU@1224|Proteobacteria,1T3AW@1236|Gammaproteobacteria,46D4B@72275|Alteromonadaceae 1236|Gammaproteobacteria S Beta-L-arabinofuranosidase, GH127 - - - - - - - - - - - - - k141_8106_2 1288826.MSNKSG1_06853 2.32e-61 194.0 COG0110@1|root,COG0110@2|Bacteria,1RDQE@1224|Proteobacteria,1S3RJ@1236|Gammaproteobacteria,466XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Acetyltransferase (Isoleucine patch superfamily) - - - - - - - - - - - - Hexapep,Hexapep_2 k141_13608_1 1089547.KB913013_gene2859 1.37e-15 82.0 COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - PKD,Peptidase_S8,fn3 k141_21991_2 1056820.KB900674_gene2495 5.34e-46 157.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1S4U5@1236|Gammaproteobacteria,2PQ1Q@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K01090,ko:K11890,ko:K20074 ko02025,map02025 - - - ko00000,ko00001,ko01000,ko01009,ko02044 - - - PP2C_2 k141_10849_1 626887.J057_02845 1.89e-20 87.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,4667F@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 k141_10849_2 1288826.MSNKSG1_01848 9.51e-263 719.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,464P0@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_2 k141_10849_3 1288826.MSNKSG1_01853 5.29e-205 568.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,1RMMY@1236|Gammaproteobacteria,464MY@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k141_10849_4 1288826.MSNKSG1_01858 0.0 1047.0 COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,465CI@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria vgrG GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564 - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Phage_GPD k141_21320_1 1469613.JT55_07295 1.25e-100 313.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,3FCW9@34008|Rhodovulum 28211|Alphaproteobacteria M Transglycosylase mrcB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k141_14985_1 1298593.TOL_0771 1e-68 219.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XIHM@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k141_14985_2 765912.Thimo_1678 1.99e-62 194.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1WYGS@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k141_14985_3 1049564.TevJSym_ao00050 1.14e-94 287.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P k141_5236_1 768671.ThimaDRAFT_3347 1.19e-60 201.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales 135613|Chromatiales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 k141_12244_1 207954.MED92_08211 4.4e-133 398.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XJGP@135619|Oceanospirillales 135619|Oceanospirillales N Flagellar hook protein flgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k141_10097_2 1049564.TevJSym_ak00120 6.72e-65 206.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1J6UB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D AAA domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k141_19239_1 1196835.A458_11055 5.97e-81 258.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1Z1XH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria KLT Serine threonine protein phosphatase - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase k141_3200_1 56110.Oscil6304_1271 2.69e-23 102.0 COG0675@1|root,COG0675@2|Bacteria,1FZWK@1117|Cyanobacteria,1H7MR@1150|Oscillatoriales 1117|Cyanobacteria L Putative transposase DNA-binding domain - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k141_10098_1 986075.CathTA2_0037 1.46e-25 101.0 2AHMV@1|root,317ZT@2|Bacteria,1VPFH@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k141_21992_1 1122137.AQXF01000001_gene3200 2.29e-88 262.0 COG0589@1|root,COG0589@2|Bacteria,1R9XB@1224|Proteobacteria,2U59E@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Universal stress protein - - - - - - - - - - - - Usp k141_20708_2 1278309.KB907099_gene2656 2.45e-98 304.0 COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,1XH3C@135619|Oceanospirillales 135619|Oceanospirillales KQ transcriptional regulator - - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat k141_17223_2 644107.SL1157_1581 2.33e-16 72.8 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,4NCP0@97050|Ruegeria 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k141_17223_3 2340.JV46_07280 1.96e-36 125.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1J6GF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k141_16523_1 1123253.AUBD01000006_gene836 6.7e-06 47.8 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X55Q@135614|Xanthomonadales 135614|Xanthomonadales EH component I pabB - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k141_16523_2 765911.Thivi_0021 1.95e-61 198.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 k141_13082_1 999550.KI421507_gene2398 8.41e-48 157.0 COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - SH3_4 k141_6044_1 1144319.PMI16_02666 5.77e-24 92.4 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,474TX@75682|Oxalobacteraceae 28216|Betaproteobacteria K 'Cold-shock' DNA-binding domain cspD2 - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_6044_2 28258.KP05_08370 5.19e-13 65.5 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1XKHN@135619|Oceanospirillales 135619|Oceanospirillales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS k141_15866_1 1123355.JHYO01000008_gene2613 3.04e-20 82.0 2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,2UXGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3012) - - - - - - - - - - - - DUF3012 k141_15866_2 1056512.D515_01104 9.26e-69 210.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1XXE0@135623|Vibrionales 135623|Vibrionales J COG1186 Protein chain release factor B yaeJ - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_15866_3 1278309.KB907101_gene486 4.62e-298 838.0 COG4564@1|root,COG5001@1|root,COG4564@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_9,Reg_prop,Y_Y_Y,dCache_2 k141_527_1 42565.FP66_02095 5.3e-39 135.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1XJKM@135619|Oceanospirillales 135619|Oceanospirillales J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_527_2 287.DR97_2870 1.95e-71 223.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1YEDQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D Necessary for normal cell division and for the maintenance of normal septation engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k141_4720_1 1123401.JHYQ01000001_gene1884 3.43e-73 233.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 k141_18610_1 686340.Metal_2645 9e-61 188.0 COG1742@1|root,COG1742@2|Bacteria,1MZI8@1224|Proteobacteria,1SA4U@1236|Gammaproteobacteria,1XGXG@135618|Methylococcales 135618|Methylococcales S Uncharacterised BCR, YnfA/UPF0060 family - - - - - - - - - - - - UPF0060 k141_18610_2 1123360.thalar_01367 1.65e-248 695.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - ko:K03319,ko:K09477,ko:K11106,ko:K14445 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.47,2.A.47.1,2.A.47.3.2,2.A.47.3.3 - - Na_sulph_symp k141_14378_1 1049564.TevJSym_au00430 6.58e-56 192.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1J524@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k141_14378_2 396588.Tgr7_0954 1.47e-21 94.4 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales 135613|Chromatiales Q PFAM methyltransferase - - - - - - - - - - - - Methyltransf_11 k141_5413_1 493475.GARC_3502 7.94e-10 59.7 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,464Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria T GGDEF domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9 k141_3319_1 1288826.MSNKSG1_02966 2.49e-50 179.0 COG1073@1|root,COG1073@2|Bacteria,1NVTC@1224|Proteobacteria,1RNXQ@1236|Gammaproteobacteria,464FA@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1073 Hydrolases of the alpha beta superfamily - - - - - - - - - - - - Lipase_bact_N k141_3319_2 1288826.MSNKSG1_02971 0.0 1010.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,4643Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumA GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1778,iPC815.YPO3335 Fumerase,Fumerase_C k141_20709_1 1129794.C427_4193 2.65e-12 70.5 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k141_17975_1 1208321.D104_15290 4.63e-73 226.0 COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XJ8R@135619|Oceanospirillales 135619|Oceanospirillales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k141_18611_1 1423144.Gal_02441 0.000106 42.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,34FRD@302485|Phaeobacter 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_18611_2 1123360.thalar_01275 4.11e-76 233.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the complex I subunit 6 family nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 k141_13777_1 1298858.AUEL01000013_gene5011 2.68e-93 285.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,43IV4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family y4uB - - - - - - - - - - - Aminotran_3 k141_1240_1 1288826.MSNKSG1_05521 1.53e-147 417.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,466QM@72275|Alteromonadaceae 1236|Gammaproteobacteria U General secretion pathway protein J gspJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ k141_1240_2 1288826.MSNKSG1_05516 6.47e-81 240.0 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,468WY@72275|Alteromonadaceae 1236|Gammaproteobacteria NU General secretion pathway protein I gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI k141_1240_3 1288826.MSNKSG1_05511 2.13e-118 339.0 COG4970@1|root,COG4970@2|Bacteria,1QXFS@1224|Proteobacteria,1T3AT@1236|Gammaproteobacteria,46D49@72275|Alteromonadaceae 1236|Gammaproteobacteria U general secretion pathway protein H gspH - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl k141_1240_4 1288826.MSNKSG1_05506 2.72e-97 283.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,467BP@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG2165 Type II secretory pathway, pseudopilin PulG gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k141_4721_1 1158762.KB898049_gene761 2.19e-16 83.6 COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,1WXFR@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K20977 ko02020,ko02025,map02020,map02025 M00820 - - ko00000,ko00001,ko00002,ko02022 - - - HATPase_c_2,Response_reg,SpoIIE k141_6708_2 1288826.MSNKSG1_09328 4.65e-193 536.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria 1236|Gammaproteobacteria N With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine motA GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0008150,GO:0009288,GO:0009425,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0120100,GO:0120101 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_6708_3 1288826.MSNKSG1_09333 2.78e-44 150.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,4656J@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase k141_13083_3 293613.A1E_00100 3.54e-09 57.8 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,47EYQ@766|Rickettsiales 766|Rickettsiales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_9488_1 349521.HCH_02127 5.18e-06 49.3 2EPM2@1|root,32UXG@2|Bacteria 2|Bacteria S PilZ domain - - - - - - - - - - - - PilZ k141_11657_1 1101195.Meth11DRAFT_1563 2.45e-110 328.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KKW1@206350|Nitrosomonadales 206350|Nitrosomonadales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k141_3955_1 1049564.TevJSym_ag00680 1.44e-76 240.0 COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,1RYIC@1236|Gammaproteobacteria 1236|Gammaproteobacteria C FAD dependent oxidoreductase - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388,ko:K16885 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - FAD_oxidored,Pyr_redox_2 k141_3320_1 305900.GV64_07840 3.65e-34 128.0 COG0179@1|root,COG0179@2|Bacteria,1MW82@1224|Proteobacteria,1RQYW@1236|Gammaproteobacteria,1XHSD@135619|Oceanospirillales 135619|Oceanospirillales Q Fumarylacetoacetase - - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FAA_hydrolase,FAA_hydrolase_N k141_528_1 472759.Nhal_3943 3.71e-129 387.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales 135613|Chromatiales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS k141_8226_1 1288826.MSNKSG1_04566 0.0 1184.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,4654Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX k141_8226_2 1288826.MSNKSG1_04571 4.64e-74 227.0 COG0834@1|root,COG0834@2|Bacteria,1NCKT@1224|Proteobacteria,1SD6E@1236|Gammaproteobacteria,46DIV@72275|Alteromonadaceae 1236|Gammaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k141_10988_1 1278309.KB907100_gene2168 1.62e-10 59.7 COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1SYC9@1236|Gammaproteobacteria,1XRJI@135619|Oceanospirillales 135619|Oceanospirillales P (ABC) transporter - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k141_10988_2 1278309.KB907100_gene2169 2.18e-167 469.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1RPXK@1236|Gammaproteobacteria,1XIHE@135619|Oceanospirillales 135619|Oceanospirillales ET belongs to the bacterial solute-binding protein 3 family - - - ko:K02030,ko:K10014,ko:K10022 ko02010,map02010 M00226,M00235,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.1,3.A.1.3.11 - - SBP_bac_3 k141_10988_3 1278309.KB907100_gene2170 9.36e-122 351.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,1XHMI@135619|Oceanospirillales 135619|Oceanospirillales E ATP-binding protein - - 3.6.3.21 ko:K02028,ko:K10025 ko02010,map02010 M00235,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.11 - - ABC_tran k141_16524_1 1288826.MSNKSG1_00216 7.49e-53 173.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,464WM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004161,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - iPC815.YPO3176,iSFV_1184.SFV_0386 polyprenyl_synt k141_16524_2 1288826.MSNKSG1_00221 4.13e-36 124.0 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,4690N@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_16524_3 1288826.MSNKSG1_00226 1.78e-122 352.0 COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,4678K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 k141_17976_1 1117647.M5M_00520 4.66e-48 175.0 COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RYVF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA replication and repair protein RecF - - - - - - - - - - - - AAA_29,SbcCD_C k141_10254_1 1278309.KB907099_gene2857 1.79e-146 422.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1XIGG@135619|Oceanospirillales 135619|Oceanospirillales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtC - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_10254_2 1278309.KB907099_gene2856 4.26e-195 545.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1XHPK@135619|Oceanospirillales 135619|Oceanospirillales P ABC-type nitrate sulfonate bicarbonate transport system, permease component nrtB - - ko:K15577 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - BPD_transp_1 k141_17977_1 232348.ADXL01000091_gene455 3.23e-15 79.7 COG2801@1|root,COG2801@2|Bacteria,1G5RM@1117|Cyanobacteria,1GZMX@1129|Synechococcus 1117|Cyanobacteria L Transposase and inactivated derivatives - - - - - - - - - - - - HTH_32,rve k141_6045_1 1131813.AQVT01000001_gene898 4.48e-76 247.0 COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2TU8Z@28211|Alphaproteobacteria,1JTH5@119045|Methylobacteriaceae 28211|Alphaproteobacteria P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k141_18612_1 270374.MELB17_20871 3.1e-114 342.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_22104_2 1286106.MPL1_06517 2.35e-35 132.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,4616P@72273|Thiotrichales 72273|Thiotrichales Q toluene tolerance - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC k141_3340_2 555778.Hneap_2072 7.83e-53 171.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1WXZY@135613|Chromatiales 135613|Chromatiales S Sulfur oxidation protein SoxY - - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY k141_3340_3 1469245.JFBG01000056_gene2481 3.64e-30 113.0 COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,1WYSI@135613|Chromatiales 135613|Chromatiales C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K17223 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C,Cytochrome_CBB3 k141_5432_1 765912.Thimo_3702 1.61e-84 267.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas k141_22125_1 1163617.SCD_n00042 9.79e-64 202.0 2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,2VUGJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2846) - - - - - - - - - - - - DUF2846 k141_22125_2 1122599.AUGR01000005_gene1830 7.77e-79 249.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XI7A@135619|Oceanospirillales 135619|Oceanospirillales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_21467_1 748247.AZKH_1794 2.44e-32 115.0 COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,2VTP9@28216|Betaproteobacteria 28216|Betaproteobacteria KT Response regulator receiver domain - - - - - - - - - - - - Response_reg k141_21467_2 261292.Nit79A3_3076 1.11e-42 164.0 COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,2VK4W@28216|Betaproteobacteria,372YF@32003|Nitrosomonadales 28216|Betaproteobacteria T Signal transduction histidine kinase, phosphotransfer (Hpt) - - - - - - - - - - - - GGDEF,Hpt,Response_reg k141_6067_1 225937.HP15_2391 4.46e-92 281.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - Polysacc_synt k141_13799_1 1288826.MSNKSG1_04711 3.04e-38 130.0 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,1SFHW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 k141_14389_1 391615.ABSJ01000035_gene1009 1.27e-179 543.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_8836_1 84531.JMTZ01000059_gene2521 3.37e-79 250.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1X39P@135614|Xanthomonadales 135614|Xanthomonadales P Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_8836_2 688245.CtCNB1_0203 7.56e-20 82.8 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,4AE4W@80864|Comamonadaceae 28216|Betaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II k141_9508_1 643867.Ftrac_2008 1.59e-13 68.6 COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes,47R6J@768503|Cytophagia 976|Bacteroidetes S Lipopolysaccharide-assembly, LptC-related - - - - - - - - - - - - LptC k141_15135_1 595494.Tola_0632 0.0 1029.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1Y3MV@135624|Aeromonadales 135624|Aeromonadales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 k141_20716_1 1278309.KB907101_gene535 6.93e-264 726.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,1XHKQ@135619|Oceanospirillales 135619|Oceanospirillales P Ammonium transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k141_3341_1 1122599.AUGR01000016_gene2858 1.72e-133 386.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XH3I@135619|Oceanospirillales 135619|Oceanospirillales M UDP-glucose 4-epimerase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k141_10277_2 395493.BegalDRAFT_1290 7.64e-56 181.0 COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1SZTK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved hypothetical ATP binding protein - - - - - - - - - - - - ATP_bind_1 k141_22127_1 706587.Desti_2549 7.64e-12 68.2 COG0348@1|root,COG1143@1|root,COG1149@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1149@2|Bacteria,1QUNB@1224|Proteobacteria,43BMZ@68525|delta/epsilon subdivisions,2X701@28221|Deltaproteobacteria,2MQGZ@213462|Syntrophobacterales 28221|Deltaproteobacteria C PFAM 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_4,Fer4_5 k141_18639_1 1288826.MSNKSG1_17376 2.7e-70 218.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,464U7@72275|Alteromonadaceae 1236|Gammaproteobacteria S stress-induced protein yicC GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - DUF1732,YicC_N k141_18639_2 1288826.MSNKSG1_17371 1.81e-163 458.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,464J3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k141_19366_1 1049564.TevJSym_ak00290 4.14e-53 171.0 COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,1S5W4@1236|Gammaproteobacteria,1J7C6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria OU NfeD-like C-terminal, partner-binding ybbJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07340 - - - - ko00000 - - - NfeD k141_19366_2 1282876.BAOK01000002_gene901 4.62e-20 90.1 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,4BPFE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O prohibitin homologues qmcA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Band_7,Band_7_C k141_538_1 1288826.MSNKSG1_00541 2.58e-128 368.0 COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria 1236|Gammaproteobacteria C it plays a direct role in the translocation of protons across the membrane - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_538_2 1288826.MSNKSG1_00536 3.6e-42 139.0 COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k141_538_3 686340.Metal_2548 7.93e-34 129.0 COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria,1XFA4@135618|Methylococcales 135618|Methylococcales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP k141_538_4 1288826.MSNKSG1_00526 7.54e-309 848.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA1 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_21583_2 1205683.CAKR01000009_gene1796 1.72e-103 308.0 COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,41FBH@629|Yersinia 1236|Gammaproteobacteria F Synthesizes selenophosphate from selenide and ATP selD GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574 AIRS,AIRS_C k141_9648_1 314231.FP2506_09386 2.78e-26 103.0 COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,2U5RY@28211|Alphaproteobacteria,2PKUR@255475|Aurantimonadaceae 28211|Alphaproteobacteria K Repressor involved in choline regulation of the bet genes betI - - ko:K02167 - - - - ko00000,ko03000 - - - TetR_C_6,TetR_N k141_9648_2 999550.KI421507_gene2067 9.05e-33 124.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG3119 Arylsulfatase A and related enzymes betC - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - Choline_sulf_C,DUF4976,Sulfatase k141_17349_1 870187.Thini_1765 3.37e-131 377.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,45ZTM@72273|Thiotrichales 72273|Thiotrichales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran k141_2714_1 1121035.AUCH01000002_gene1569 2.59e-15 82.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KUNX@206389|Rhodocyclales 206389|Rhodocyclales T Histidine Phosphotransfer domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS,Response_reg k141_641_1 344747.PM8797T_21833 0.000105 57.0 COG0652@1|root,COG1470@1|root,COG1864@1|root,COG3210@1|root,COG3391@1|root,COG0652@2|Bacteria,COG1470@2|Bacteria,COG1864@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,2IXHS@203682|Planctomycetes 203682|Planctomycetes O Peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - He_PIG,Pro_isomerase k141_13932_1 511062.GU3_05795 2.65e-18 78.2 2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S type III effector hopJ - - - - - - - - - - - HopJ k141_13932_2 1049564.TevJSym_ah00580 1.22e-120 347.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1J4D9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0450 Peroxiredoxin tsaA - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA k141_10435_1 861299.J421_1914 2.25e-26 99.4 COG1278@1|root,COG1278@2|Bacteria 2|Bacteria K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_11747_2 930169.B5T_03514 1.62e-40 156.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XKXU@135619|Oceanospirillales 135619|Oceanospirillales M COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - - - - - - - - - - Sulfatase k141_6809_1 1565129.JSFF01000017_gene2879 2.02e-67 221.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,2Q92G@267890|Shewanellaceae 1236|Gammaproteobacteria P Citrate transporter nhaD - - - - - - - - - - - CitMHS k141_6192_1 396588.Tgr7_1327 3.25e-27 106.0 COG1580@1|root,COG1580@2|Bacteria,1N2N9@1224|Proteobacteria,1SAF0@1236|Gammaproteobacteria,1WZ98@135613|Chromatiales 135613|Chromatiales N Controls the rotational direction of flagella during chemotaxis - - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_6192_2 765914.ThisiDRAFT_0156 1.01e-150 433.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1WWMX@135613|Chromatiales 135613|Chromatiales N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C k141_22256_11 1196028.ALEF01000043_gene479 2.15e-89 272.0 COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,4HCF9@91061|Bacilli,4C694@84406|Virgibacillus 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k141_22256_12 118173.KB235910_gene4689 3.72e-32 136.0 COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria,1H9Z1@1150|Oscillatoriales 1117|Cyanobacteria L 'Superfamily II - - - - - - - - - - - - Helicase_C,ResIII k141_22256_14 1465639.A0A060BL17_9CAUD 8.93e-73 234.0 4QAXN@10239|Viruses,4QVNW@35237|dsDNA viruses no RNA stage,4QPV1@28883|Caudovirales 28883|Caudovirales S D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - - k141_22256_15 469616.FMAG_02606 1.61e-63 206.0 COG0863@1|root,COG0863@2|Bacteria,37CTG@32066|Fusobacteria 32066|Fusobacteria L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k141_22256_17 751945.Theos_1690 4.3e-32 125.0 2CHRY@1|root,30Z9E@2|Bacteria,1WN8T@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - k141_22256_36 1380387.JADM01000008_gene942 2.15e-92 291.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1RMTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k141_22256_47 471874.PROSTU_04412 1.98e-79 252.0 2BZ9Z@1|root,2Z97E@2|Bacteria,1RD7Q@1224|Proteobacteria,1S06R@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_22256_62 306263.Cla_0843 0.000254 45.4 2C4D9@1|root,33FB1@2|Bacteria,1NMSX@1224|Proteobacteria,42W0V@68525|delta/epsilon subdivisions,2YQB1@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k141_22256_69 1244869.H261_11004 1.33e-15 84.0 2DBA1@1|root,2Z80P@2|Bacteria,1MW1Q@1224|Proteobacteria,2TVGH@28211|Alphaproteobacteria,2JW3D@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k141_22256_74 1415630.U771_15235 1.88e-17 96.3 COG5185@1|root,COG5185@2|Bacteria,1R2WJ@1224|Proteobacteria,1T5Z8@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k141_22256_77 1244869.H261_11074 5.06e-27 126.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,2JV2T@204441|Rhodospirillales 204441|Rhodospirillales S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Lambda_tail_I,Phage-tail_3 k141_21600_1 864051.BurJ1DRAFT_3552 4.92e-16 75.9 COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KM3I@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Dihaem cytochrome c - - - - - - - - - - - - DHC k141_21600_2 765913.ThidrDRAFT_1546 1.35e-29 110.0 COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,1S8J5@1236|Gammaproteobacteria,1WYMT@135613|Chromatiales 135613|Chromatiales C Domain of unknown function (DUF1924) - - - - - - - - - - - - DUF1924 k141_11765_1 519989.ECTPHS_04299 2.88e-22 101.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1X1FM@135613|Chromatiales 135613|Chromatiales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL k141_2035_2 1255043.TVNIR_1527 7.09e-32 112.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales 135613|Chromatiales K PFAM Cold-shock protein, DNA-binding - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k141_2035_3 1095769.CAHF01000007_gene1691 1.46e-82 256.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,472Q2@75682|Oxalobacteraceae 28216|Betaproteobacteria I Transposase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase k141_670_1 1036674.A28LD_1745 3.27e-51 176.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,2QF87@267893|Idiomarinaceae 1236|Gammaproteobacteria J histidyl-tRNA synthetase hisS GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358 HGTP_anticodon,tRNA-synt_His k141_670_2 29495.EA26_03910 7.02e-10 58.5 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1Y2NR@135623|Vibrionales 135623|Vibrionales S Tetratricopeptide repeat-like domain - - - - - - - - - - - - TPR_21 k141_16686_1 349521.HCH_00962 3.89e-105 318.0 COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XHE6@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,CbiA,GATase_3 k141_5731_1 1278309.KB907100_gene1867 4.34e-15 73.6 COG0392@1|root,COG0392@2|Bacteria,1RM0R@1224|Proteobacteria,1T0HH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM k141_5731_2 1278309.KB907100_gene1868 3.47e-225 623.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XHPM@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k141_5731_3 1278309.KB907100_gene1869 7.49e-128 367.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1XJCK@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB k141_5731_4 1278309.KB907100_gene1870 1.58e-44 145.0 COG2921@1|root,COG2921@2|Bacteria,1QSYF@1224|Proteobacteria,1RWKJ@1236|Gammaproteobacteria,1XMEF@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 k141_5731_5 1278309.KB907100_gene1871 2.58e-174 489.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1XI1R@135619|Oceanospirillales 135619|Oceanospirillales E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction dat - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 k141_5731_6 1278309.KB907100_gene1872 1.63e-199 558.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XI5M@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the peptidase S11 family dacA - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_9867_1 420662.Mpe_A3582 1.12e-95 289.0 COG5424@1|root,COG5424@2|Bacteria,1R7J8@1224|Proteobacteria,2VP7H@28216|Betaproteobacteria 28216|Betaproteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k141_18255_1 1288826.MSNKSG1_12652 0.0 1288.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - DUF1631,EAL,GGDEF,PilZ k141_13384_1 1348657.M622_01660 1.32e-14 70.5 COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,2KX24@206389|Rhodocyclales 206389|Rhodocyclales K Protein of unknown function (DUF3579) - - - - - - - - - - - - DUF3579 k141_13384_2 396588.Tgr7_0698 1.55e-89 280.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1WX4U@135613|Chromatiales 135613|Chromatiales T PFAM Metal-dependent phosphohydrolase, HD - - - - - - - - - - - - DUF3391,HD_5 k141_11316_1 1454202.PPBDW_60040___1 9.26e-260 734.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1XVW9@135623|Vibrionales 135623|Vibrionales V COG0286 Type I restriction-modification system methyltransferase subunit - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k141_7820_1 713586.KB900536_gene2310 1.15e-247 685.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1WWJ4@135613|Chromatiales 135613|Chromatiales S Radical SAM superfamily pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k141_7820_2 1255043.TVNIR_1647 2.69e-80 242.0 COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,1S7GD@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Nitrite reductase heme biosynthesis H protein nirH - - - - - - - - - - - HTH_AsnC-type k141_7820_3 713586.KB900536_gene2308 5.06e-71 217.0 COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,1S8HH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K heme biosynthesis protein nirG - - - - - - - - - - - HTH_AsnC-type k141_7820_4 1255043.TVNIR_1645 1.55e-43 147.0 COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,1S620@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG1522 Transcriptional regulators nirL - - - - - - - - - - - HTH_AsnC-type k141_19641_1 1278309.KB907099_gene2721 6.71e-36 125.0 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1XJMK@135619|Oceanospirillales 135619|Oceanospirillales C Thioredoxin-like [2Fe-2S] ferredoxin - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - 2Fe-2S_thioredx k141_19641_2 1278309.KB907099_gene2720 0.0 947.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales 135619|Oceanospirillales C NADH-quinone oxidoreductase subunit F fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB k141_6390_3 648757.Rvan_1818 1.89e-121 383.0 COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2TY55@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Bacterial type II and III secretion system protein pilQ - - ko:K02453,ko:K02666 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - Secretin,Secretin_N k141_2212_1 439235.Dalk_5147 2.96e-46 168.0 COG3266@1|root,COG3267@1|root,COG3409@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales 28221|Deltaproteobacteria U PFAM Peptidoglycan-binding domain 1 protein - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 k141_2212_2 1280946.HY29_06600 1.02e-50 170.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,43Y2Q@69657|Hyphomonadaceae 28211|Alphaproteobacteria K response regulator fixJ - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_12676_1 870187.Thini_4191 2.79e-38 141.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,45ZT2@72273|Thiotrichales 72273|Thiotrichales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_12676_2 444878.E3SR12_9CAUD 9.42e-12 64.3 4QB9C@10239|Viruses,4QWED@35237|dsDNA viruses no RNA stage,4QTNA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k141_12676_3 985054.JQEZ01000001_gene1948 1.66e-79 253.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4NCCE@97050|Ruegeria 28211|Alphaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 k141_12676_4 28229.ND2E_3900 1.46e-20 92.4 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria,2Q71A@267889|Colwelliaceae 1236|Gammaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 k141_97_1 287.DR97_3825 1.49e-13 66.6 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1YGT6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S k141_97_2 1278309.KB907100_gene1967 7.25e-163 461.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XHEV@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt k141_97_3 1278309.KB907100_gene1968 5.15e-52 178.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XHE2@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C k141_18968_1 1336243.JAEA01000002_gene2598 3.49e-29 114.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,1JT1M@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM ATPase associated with various cellular activities AAA_3 moxR GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k141_18968_2 1530186.JQEY01000004_gene1967 3.27e-60 197.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) MA20_44650 - - - - - - - - - - - DUF58 k141_20382_1 1288826.MSNKSG1_06648 0.0 1412.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,465XA@72275|Alteromonadaceae 1236|Gammaproteobacteria KL COG1199 Rad3-related DNA helicases dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_20382_2 1288826.MSNKSG1_06653 4.43e-135 385.0 2DRAW@1|root,33B0D@2|Bacteria,1QXFT@1224|Proteobacteria,1T3AV@1236|Gammaproteobacteria,468VR@72275|Alteromonadaceae 1236|Gammaproteobacteria S Type II secretion system protein B - - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB k141_20382_3 1288826.MSNKSG1_06658 8.91e-135 395.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,4658U@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG3267 Type II secretory pathway, component ExeA gspA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 k141_4313_1 1288826.MSNKSG1_05286 3.79e-83 245.0 2E652@1|root,330TV@2|Bacteria,1NB4A@1224|Proteobacteria,1SD67@1236|Gammaproteobacteria,46BSW@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4313_2 1288826.MSNKSG1_05281 5.49e-207 573.0 COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,466DB@72275|Alteromonadaceae 1236|Gammaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family nhaR - - ko:K03717 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k141_4313_3 1288826.MSNKSG1_05276 2.09e-148 417.0 COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,1RR4T@1236|Gammaproteobacteria,467EN@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct k141_4313_4 1288826.MSNKSG1_05271 2.61e-263 724.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,465JY@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 k141_4313_5 1288826.MSNKSG1_05266 9.25e-189 525.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,4648H@72275|Alteromonadaceae 1236|Gammaproteobacteria NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_14077_1 857087.Metme_2375 8.81e-93 308.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales 135618|Methylococcales T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GGDEF,Response_reg k141_14077_2 1238450.VIBNISOn1_1430098 9.49e-14 81.3 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTC9@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - - - - - - - - - - MCPsignal,dCache_1 k141_14077_3 998088.B565_3175 1.27e-54 173.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1Y5YH@135624|Aeromonadales 135624|Aeromonadales T cheY-homologous receiver domain - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_14077_5 1122604.JONR01000020_gene488 7.06e-06 52.4 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k141_16860_1 1249627.D779_2403 1.63e-101 300.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales 135613|Chromatiales O TIGRFAM FeS assembly ATPase SufC - - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k141_16860_2 246197.MXAN_1155 5.55e-25 108.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2Z0A5@29|Myxococcales 28221|Deltaproteobacteria O FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 k141_4980_2 1288826.MSNKSG1_02454 4.38e-174 487.0 COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,466E6@72275|Alteromonadaceae 1236|Gammaproteobacteria S epimerase, PhzC PhzF homolog yddE - - - - - - - - - - - PhzC-PhzF k141_4980_3 1288826.MSNKSG1_02449 5.33e-286 781.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,465GF@72275|Alteromonadaceae 1236|Gammaproteobacteria S flavoproteins yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like k141_4980_4 1122603.ATVI01000010_gene936 4.8e-52 167.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S990@1236|Gammaproteobacteria,1X7H2@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_4980_5 270374.MELB17_08851 4.21e-137 392.0 COG3473@1|root,COG3473@2|Bacteria,1N3F7@1224|Proteobacteria,1RQGE@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the conversion of maleate to fumarate maiA - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race k141_4980_6 270374.MELB17_08846 9.77e-297 818.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k141_4996_3 1158756.AQXQ01000012_gene1699 1.38e-28 111.0 COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,1RNKV@1236|Gammaproteobacteria,1WW87@135613|Chromatiales 135613|Chromatiales S Bacterial lipid A biosynthesis acyltransferase - - - - - - - - - - - - Lip_A_acyltrans k141_16163_2 754477.Q7C_2633 5.35e-06 49.7 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria,460XW@72273|Thiotrichales 72273|Thiotrichales NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k141_5754_2 1116472.MGMO_141c00070 3.89e-111 327.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,1XE0S@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF815) - - - ko:K06923 - - - - ko00000 - - - DUF815 k141_18978_1 1163617.SCD_n00693 2.88e-58 196.0 COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2VPGJ@28216|Betaproteobacteria 28216|Betaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA2 - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k141_3640_1 1123368.AUIS01000019_gene1205 2.27e-43 152.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA k141_19661_1 1298593.TOL_2732 4.18e-73 245.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XHKH@135619|Oceanospirillales 135619|Oceanospirillales F Carbamoyl-phosphate synthetase ammonia chain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k141_4332_1 1249627.D779_0874 1.66e-38 134.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1WY0F@135613|Chromatiales 135613|Chromatiales P PFAM Rhodanese-like - - - - - - - - - - - - Rhodanese k141_4332_2 933262.AXAM01000004_gene2387 2.25e-27 102.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,4375Q@68525|delta/epsilon subdivisions,2X23D@28221|Deltaproteobacteria,2MMCJ@213118|Desulfobacterales 28221|Deltaproteobacteria O Glutaredoxin - - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k141_4332_3 580332.Slit_2205 2.63e-66 205.0 COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,44VT6@713636|Nitrosomonadales 28216|Betaproteobacteria O Thioredoxin trxC - 1.8.1.8 ko:K03672 - - - - ko00000,ko01000,ko03110 - - - Thioredoxin k141_10620_1 323848.Nmul_A1553 2.85e-09 58.2 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,373I3@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 k141_9881_1 1245471.PCA10_37860 1.43e-43 155.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1YEMY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L DNA polymerase III, delta subunit, C terminal holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k141_21730_1 1049564.TevJSym_bg00260 1.66e-109 325.0 COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_5 k141_21730_2 1049564.TevJSym_bg00250 5.88e-179 522.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,1J4NX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P von Willebrand factor (vWF) type A domain norD - - ko:K02448 - - R00294 RC02794 ko00000 3.D.4.10 - - VWA,VWA_2 k141_11338_1 317025.Tcr_1635 1.18e-118 354.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4602E@72273|Thiotrichales 72273|Thiotrichales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k141_4333_2 1535422.ND16A_3571 1.07e-07 52.4 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2Q707@267889|Colwelliaceae 1236|Gammaproteobacteria L Transposase - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k141_9186_1 367336.OM2255_08581 1.38e-49 167.0 COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2TW57@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane transporter protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07090 - - - - ko00000 - - - TauE k141_9186_2 1202962.KB907159_gene3263 9.09e-14 70.9 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C k141_7832_1 870187.Thini_4142 2.6e-86 266.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,462PQ@72273|Thiotrichales 72273|Thiotrichales CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C k141_4997_1 686340.Metal_0262 3.84e-09 55.8 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XF41@135618|Methylococcales 135618|Methylococcales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB k141_4997_2 472759.Nhal_2446 2.84e-67 208.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1WX65@135613|Chromatiales 135613|Chromatiales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase k141_4997_3 105559.Nwat_1075 1.49e-112 334.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 k141_1538_2 998088.B565_3855 4.56e-102 301.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1Y3KB@135624|Aeromonadales 135624|Aeromonadales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran k141_1538_3 713586.KB900536_gene2324 5.63e-65 206.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WZW4@135613|Chromatiales 135613|Chromatiales L Endonuclease/Exonuclease/phosphatase family - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k141_119_1 287.DR97_2708 1.41e-29 106.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1YGRU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_119_2 1452718.JBOY01000097_gene2976 1.64e-32 119.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_10621_1 864051.BurJ1DRAFT_3355 4.24e-47 157.0 2DZRC@1|root,32VGV@2|Bacteria,1N3WQ@1224|Proteobacteria,2VVKX@28216|Betaproteobacteria,1KNWW@119065|unclassified Burkholderiales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_15519_1 1288826.MSNKSG1_06238 8.56e-160 450.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,465C9@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k141_15519_2 1288826.MSNKSG1_06243 1.87e-90 275.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,464X8@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - iJN746.PP_2734 CMAS k141_19662_1 1234364.AMSF01000068_gene2137 5.03e-40 141.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S5DB@1236|Gammaproteobacteria,1X4XD@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF502) YH67_14670 - - - - - - - - - - - DUF502 k141_2228_1 1288826.MSNKSG1_10848 9.29e-164 459.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,4675Y@72275|Alteromonadaceae 1236|Gammaproteobacteria M effector of murein hydrolase yohK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - LrgB k141_18266_1 1278309.KB907100_gene2182 8.74e-38 140.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XI8B@135619|Oceanospirillales 135619|Oceanospirillales M protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA k141_18266_2 1278309.KB907100_gene2181 1.53e-137 389.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1XIRE@135619|Oceanospirillales 135619|Oceanospirillales E Imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD k141_18266_3 1278309.KB907100_gene2180 1.83e-147 416.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XHZW@135619|Oceanospirillales 135619|Oceanospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase k141_15639_2 1288826.MSNKSG1_09428 1.41e-240 662.0 COG0715@1|root,COG0715@2|Bacteria,1QVPH@1224|Proteobacteria,1T2FY@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - k141_15639_3 1288826.MSNKSG1_09433 3.69e-255 699.0 28M2K@1|root,2ZAH0@2|Bacteria,1R6X6@1224|Proteobacteria,1RZU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8674_2 458817.Shal_0856 4.04e-59 188.0 28PNW@1|root,2ZCBD@2|Bacteria,1RIQY@1224|Proteobacteria,1SKNQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15654_1 420662.Mpe_A1272 1.15e-24 101.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,1KIUZ@119065|unclassified Burkholderiales 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_15654_2 357804.Ping_1712 1.75e-11 62.8 COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,1T0AG@1236|Gammaproteobacteria 1236|Gammaproteobacteria I phosphoesterase, PA-phosphatase - - - - - - - - - - - - PAP2 k141_21270_1 1470591.BW41_00304 1.46e-35 132.0 2BMG5@1|root,32G0V@2|Bacteria,1Q0U4@1224|Proteobacteria,2VEMD@28211|Alphaproteobacteria,2K841@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k141_21270_3 1173022.Cri9333_0623 6.55e-08 53.9 COG4422@1|root,COG4422@2|Bacteria,1G1Q2@1117|Cyanobacteria,1HA22@1150|Oscillatoriales 1117|Cyanobacteria S COG4422 Bacteriophage protein gp37 - - - - - - - - - - - - DUF5131 k141_21947_1 400668.Mmwyl1_2481 1.64e-26 103.0 COG1802@1|root,COG1802@2|Bacteria,1P6WQ@1224|Proteobacteria,1SYFS@1236|Gammaproteobacteria,1XQAF@135619|Oceanospirillales 135619|Oceanospirillales K FCD - - - - - - - - - - - - FCD,GntR k141_21947_2 400668.Mmwyl1_2482 6.4e-73 220.0 COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,1S6JH@1236|Gammaproteobacteria,1XRIX@135619|Oceanospirillales 135619|Oceanospirillales S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD k141_21947_3 101162.XP_007686437.1 4.22e-11 63.9 COG1012@1|root,KOG2451@2759|Eukaryota,38D8C@33154|Opisthokonta,3NVW2@4751|Fungi,3QNK0@4890|Ascomycota,1ZYJS@147541|Dothideomycetes,4KB3G@92860|Pleosporales 4751|Fungi E Belongs to the aldehyde dehydrogenase family UGA2 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034599,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0050896,GO:0051287,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3140_1 1278309.KB907102_gene210 5.67e-82 253.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1XRU4@135619|Oceanospirillales 135619|Oceanospirillales S FOG TPR repeat - - - - - - - - - - - - Peptidase_C39_2,Peptidase_C70,TPR_16,TPR_8 k141_3140_2 686578.AFFX01000009_gene3111 4.88e-09 53.9 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_5902_1 1358423.N180_16065 1.01e-69 222.0 28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia 976|Bacteroidetes S Putative beta-barrel porin-2, OmpL-like. bbp2 - - - - - - - - - - - - BBP2 k141_1009_1 557598.LHK_02972 7.57e-104 314.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,2KQ62@206351|Neisseriales 206351|Neisseriales EGP Acetyl-coenzyme A transporter 1 ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 k141_14240_1 754476.Q7A_1021 1.98e-53 179.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales 72273|Thiotrichales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k141_14240_2 83406.HDN1F_06760 1.19e-93 284.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1J5BU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin k141_16317_1 666509.RCA23_c15840 1.24e-74 233.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD k141_16317_2 351016.RAZWK3B_00575 3.07e-08 55.5 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2U5K0@28211|Alphaproteobacteria,2P2X9@2433|Roseobacter 28211|Alphaproteobacteria S Twin-arginine translocation pathway signal sequence domain protein - - - - - - - - - - - - Ysc84 k141_17037_1 1288826.MSNKSG1_16926 1.4e-234 648.0 COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,4672V@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2829 Outer membrane phospholipase A pldA GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0008970,GO:0009279,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044462,GO:0044464,GO:0045203,GO:0046872,GO:0046983,GO:0052689,GO:0071944 3.1.1.32,3.1.1.4 ko:K01058 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 - R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_4201,iECUMN_1333.ECUMN_4347,iEcSMS35_1347.EcSMS35_4188 PLA1 k141_322_1 1188256.BASI01000001_gene435 1.6e-158 458.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,3FE0Z@34008|Rhodovulum 28211|Alphaproteobacteria F Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k141_5168_1 640081.Dsui_1326 8.78e-46 157.0 COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,2VTQI@28216|Betaproteobacteria,2KWPB@206389|Rhodocyclales 206389|Rhodocyclales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS k141_3801_1 1448139.AI20_14115 1.74e-23 94.0 COG1366@1|root,COG1366@2|Bacteria,1N8B6@1224|Proteobacteria,1SDVH@1236|Gammaproteobacteria,1Y65X@135624|Aeromonadales 135624|Aeromonadales T STAS domain - - - - - - - - - - - - STAS_2 k141_3801_2 1282356.H045_08290 5.5e-14 67.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1YTK0@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria KT Protein involved in kinase activity, two-component response regulator activity, chemotaxis, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent IV02_18015 - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k141_14947_1 95619.PM1_0200755 7.78e-134 388.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k141_14947_2 156889.Mmc1_0871 2.13e-14 70.5 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k141_10040_1 388399.SSE37_21860 2.78e-48 169.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0277 FAD FMN-containing dehydrogenases - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 k141_18428_2 228410.NE1717 1.91e-57 186.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,3722G@32003|Nitrosomonadales 28216|Betaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k141_7295_2 1286106.MPL1_07353 3.33e-52 174.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,460C1@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 k141_1010_1 999549.KI421513_gene3183 2.55e-63 196.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,281E1@191028|Leisingera 28211|Alphaproteobacteria P Ferric uptake regulator family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_1010_2 981384.AEYW01000006_gene2974 1.84e-50 172.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,4N9R7@97050|Ruegeria 28211|Alphaproteobacteria F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k141_10803_1 224325.AF_1737 7.19e-06 55.1 COG1331@1|root,arCOG02007@2157|Archaea,2XU5Q@28890|Euryarchaeota,246VZ@183980|Archaeoglobi 183980|Archaeoglobi O N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH k141_10803_2 243924.LT42_18350 2.13e-09 67.0 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_3141_2 371731.Rsw2DRAFT_3095 1.12e-51 167.0 COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,1FC0D@1060|Rhodobacter 28211|Alphaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_11479_1 283942.IL0396 2.34e-27 114.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,2QFAU@267893|Idiomarinaceae 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k141_11479_2 498211.CJA_2804 7.77e-116 338.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1FG79@10|Cellvibrio 1236|Gammaproteobacteria S Branched-chain amino acid ATP-binding cassette transporter lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k141_14948_1 1208323.B30_07706 1.43e-20 89.4 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component dctP - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP k141_14948_2 252305.OB2597_01082 8.64e-40 139.0 COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2TU4N@28211|Alphaproteobacteria,2PDZU@252301|Oceanicola 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component dctQ - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ k141_1740_1 1042375.AFPL01000013_gene2466 4.85e-101 305.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB k141_13543_1 1049564.TevJSym_an00030 6.25e-186 533.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7AF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F 5'-nucleotidase, C-terminal domain soxB - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C k141_12888_1 1288826.MSNKSG1_16271 1.05e-82 269.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_12888_2 1288826.MSNKSG1_16266 3.11e-238 662.0 COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,1RP0X@1236|Gammaproteobacteria,464PK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 k141_12888_3 1288826.MSNKSG1_16261 2.43e-101 293.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria,4688E@72275|Alteromonadaceae 1236|Gammaproteobacteria P Ion transport 2 domain protein - - - - - - - - - - - - Ion_trans_2 k141_12888_4 1288826.MSNKSG1_16256 0.0 1207.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4663R@72275|Alteromonadaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_2402_1 1004785.AMBLS11_15170 1.1e-86 269.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,4640Z@72275|Alteromonadaceae 1236|Gammaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL k141_6546_2 523791.Kkor_0303 4.09e-54 174.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XJNA@135619|Oceanospirillales 135619|Oceanospirillales S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k141_6546_3 472759.Nhal_2770 2.1e-07 51.6 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales 135613|Chromatiales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k141_8676_1 1198232.CYCME_1885 2.86e-26 106.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales 72273|Thiotrichales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k141_8676_2 561230.PC1_3499 4.11e-42 150.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1MQUM@122277|Pectobacterium 1236|Gammaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440 Ala_racemase_C,Ala_racemase_N k141_17038_1 1469607.KK073769_gene5550 1.57e-134 420.0 COG2202@1|root,COG3852@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1HTQ5@1161|Nostocales 1117|Cyanobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k141_1011_1 95619.PM1_0211920 5.92e-91 290.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 k141_13544_2 443254.Marpi_1437 1.36e-19 86.3 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GCYC@200918|Thermotogae 200918|Thermotogae K Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2,HTH_3 k141_325_1 1122201.AUAZ01000017_gene2907 8.07e-76 236.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,464BG@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0331 (acyl-carrier-protein) S-malonyltransferase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k141_11480_1 1249627.D779_1731 1.58e-94 292.0 COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RYB6@1236|Gammaproteobacteria,1X0A2@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k141_19179_1 402777.KB235903_gene1311 2.49e-45 171.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1HA1U@1150|Oscillatoriales 1117|Cyanobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9 k141_2403_1 6669.EFX90246 1.29e-14 71.2 2CHIC@1|root,2QWKE@2759|Eukaryota,38DAH@33154|Opisthokonta,3BJXB@33208|Metazoa,3D3WI@33213|Bilateria,4207C@6656|Arthropoda 33208|Metazoa S Protein of unknown function (DUF2452) C1orf50 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - DUF2452 k141_2403_2 742823.HMPREF9465_00289 1.65e-16 76.6 COG0607@1|root,COG0607@2|Bacteria,1NGN9@1224|Proteobacteria,2VUUZ@28216|Betaproteobacteria,4PR9P@995019|Sutterellaceae 28216|Betaproteobacteria P Rhodanese Homology Domain - - - ko:K03972 - - - - ko00000 - - - Rhodanese k141_1741_1 1123237.Salmuc_01104 1.85e-21 89.4 COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator, GntR family - - - - - - - - - - - - FCD,GntR k141_1741_2 1461693.ATO10_00995 1.6e-42 145.0 COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2TUDN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Pyrimidine 5'-nucleotidase - - - ko:K07025 - - - - ko00000 - - - HAD_2 k141_7296_1 469381.Dpep_0731 8.87e-13 68.2 COG0745@1|root,COG0745@2|Bacteria,3TAJR@508458|Synergistetes 508458|Synergistetes K PFAM response regulator receiver - - - ko:K07657,ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_7296_2 1121921.KB898706_gene2854 2.58e-48 161.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,2PNQ3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK2 - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_7296_3 472759.Nhal_0031 7.73e-25 96.3 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1WYI8@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB k141_17039_1 713586.KB900536_gene2205 5.15e-16 80.9 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWTP@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K10126,ko:K10943 ko02020,ko05111,map02020,map05111 M00504,M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21271_1 1122603.ATVI01000007_gene1691 7.51e-175 496.0 COG2813@1|root,COG2813@2|Bacteria,1QWWU@1224|Proteobacteria,1T5SK@1236|Gammaproteobacteria,1XARZ@135614|Xanthomonadales 1224|Proteobacteria J Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k141_10042_1 35754.JNYJ01000007_gene2936 3.42e-14 82.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria 201174|Actinobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3 k141_5904_2 1026882.MAMP_03141 8.32e-69 221.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales 72273|Thiotrichales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_3142_1 203122.Sde_1054 2.81e-51 183.0 COG0557@1|root,COG3064@1|root,COG0557@2|Bacteria,COG3064@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k141_3142_2 1049564.TevJSym_ac00930 1.23e-61 198.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1J53F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k141_13545_1 396588.Tgr7_2294 4.84e-92 285.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_17040_1 314345.SPV1_13604 4.55e-74 239.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria 1224|Proteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS k141_9334_2 1198232.CYCME_1914 9.89e-137 415.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_14950_1 1168067.JAGP01000001_gene592 2.08e-70 219.0 COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1S357@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B k141_14950_2 1158292.JPOE01000005_gene1376 6.5e-25 102.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,2W0MI@28216|Betaproteobacteria 28216|Betaproteobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase k141_12889_1 1206777.B195_06975 1.57e-89 275.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1Z76K@136849|Pseudomonas syringae group 1236|Gammaproteobacteria T chemotaxis cheV - - ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg k141_12889_2 765913.ThidrDRAFT_2728 1.26e-12 66.6 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1WW26@135613|Chromatiales 135613|Chromatiales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k141_8678_1 1121918.ARWE01000001_gene2909 8.64e-37 139.0 COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,42SXG@68525|delta/epsilon subdivisions,2WP6Y@28221|Deltaproteobacteria,43THM@69541|Desulfuromonadales 28221|Deltaproteobacteria I SNARE associated Golgi protein - - - - - - - - - - - - LssY_C,PAP2,SNARE_assoc k141_6548_1 1049564.TevJSym_aa02510 2.68e-45 158.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1J544@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_6548_2 1231190.NA8A_18953 4.85e-07 52.8 COG3090@1|root,COG3090@2|Bacteria,1RDY3@1224|Proteobacteria,2U7K9@28211|Alphaproteobacteria,43PBU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_21272_1 326297.Sama_2059 9.43e-99 308.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,2Q8WZ@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM Isocitrate dehydrogenase NADP-dependent monomeric type icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k141_20583_1 1288826.MSNKSG1_06728 4.15e-308 861.0 COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae 1236|Gammaproteobacteria O protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,YfiO k141_20583_2 1288826.MSNKSG1_06733 0.0 939.0 COG0457@1|root,COG0457@2|Bacteria,1NXHU@1224|Proteobacteria,1SQ3D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S FOG TPR repeat - - - - - - - - - - - - - k141_20583_3 1288826.MSNKSG1_06738 3.67e-124 354.0 2B4XH@1|root,32REP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_20583_4 1288826.MSNKSG1_06743 2.53e-248 683.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,1RMRY@1236|Gammaproteobacteria,464I9@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_28405 - - ko:K09989 - - - - ko00000 - - - VWA_CoxE k141_8045_1 754476.Q7A_2838 1.68e-182 520.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales 72273|Thiotrichales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_8045_2 396588.Tgr7_0517 7.27e-267 739.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales 135613|Chromatiales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k141_8045_3 243233.MCA2980 2.88e-07 51.2 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1XEJW@135618|Methylococcales 135618|Methylococcales O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 k141_15671_2 981327.F925_00768 4.35e-42 144.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,3NKGB@468|Moraxellaceae 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k141_19199_1 1294143.H681_02065 1.18e-35 140.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_6566_2 314345.SPV1_07119 7.41e-112 332.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria 1224|Proteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k141_3815_1 722419.PH505_ah00830 5.23e-55 194.0 COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,2PZXA@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg,SBP_bac_3,dCache_1 k141_18585_1 160488.PP_2279 1.19e-66 219.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k141_12366_1 744980.TRICHSKD4_2573 7.47e-105 314.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2TS3I@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component urtA - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 k141_12366_2 930169.B5T_03327 2.63e-29 114.0 COG0583@1|root,COG0583@2|Bacteria,1MW4Y@1224|Proteobacteria,1RNJT@1236|Gammaproteobacteria,1XN24@135619|Oceanospirillales 135619|Oceanospirillales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k141_2547_1 1121035.AUCH01000001_gene1882 2.52e-53 177.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,2KUN1@206389|Rhodocyclales 206389|Rhodocyclales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO k141_19960_1 1123487.KB892834_gene2776 3.07e-11 64.7 COG2206@1|root,COG2206@2|Bacteria,1MWDU@1224|Proteobacteria,2VIAF@28216|Betaproteobacteria,2KZ48@206389|Rhodocyclales 206389|Rhodocyclales T Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD k141_16488_1 1131553.JIBI01000030_gene2437 3.89e-84 276.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,372DJ@32003|Nitrosomonadales 28216|Betaproteobacteria T Diguanylate cyclase phosphodiesterase with PAS PAC - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,Response_reg k141_7461_1 1173027.Mic7113_5686 4.75e-77 259.0 COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1H7Q7@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg k141_22075_1 1288826.MSNKSG1_10988 6.11e-148 417.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,465FY@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain narL GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg k141_22075_2 1288826.MSNKSG1_10983 2.75e-73 236.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,465S0@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG3850 Signal transduction histidine kinase, nitrate nitrite-specific narX GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA_3,PilJ k141_10226_1 1121403.AUCV01000003_gene1791 4.49e-108 321.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2MIBW@213118|Desulfobacterales 28221|Deltaproteobacteria P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 k141_20692_1 1278309.KB907100_gene2046 5.68e-85 255.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1XJXU@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the UPF0301 (AlgH) family algH - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k141_20692_2 1278309.KB907100_gene2045 3.7e-158 451.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1XJV0@135619|Oceanospirillales 135619|Oceanospirillales M Periplasmic protein TonB, links inner and outer membranes tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C k141_20692_3 1278309.KB907100_gene2044 2.46e-217 601.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1XI8S@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N k141_20692_4 1278309.KB907100_gene2043 4.19e-139 397.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XJ89@135619|Oceanospirillales 135619|Oceanospirillales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA k141_20692_5 1278309.KB907100_gene2042 3.81e-274 751.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1XHEZ@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k141_20692_6 1278309.KB907100_gene2041 3.39e-252 705.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XI3G@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k141_4688_1 1499686.BN1079_01142 4.17e-14 82.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 k141_10952_1 857087.Metme_0630 4.33e-187 530.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1XE7S@135618|Methylococcales 135618|Methylococcales S Belongs to the RtcB family rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k141_16489_1 684719.HIMB114_00002440 1.36e-16 80.9 COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_8784_1 405948.SACE_5949 6.85e-09 58.2 COG1903@1|root,COG1903@2|Bacteria,2GM41@201174|Actinobacteria,4E0I9@85010|Pseudonocardiales 201174|Actinobacteria H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A cbiD - 2.1.1.195 ko:K02188 ko00860,ko01100,map00860,map01100 - R07773 RC00003,RC02051 ko00000,ko00001,ko01000 - - - CbiD k141_8784_2 391613.RTM1035_11705 1.56e-39 140.0 COG2099@1|root,COG2099@2|Bacteria,1MW48@1224|Proteobacteria,2TWW4@28211|Alphaproteobacteria,46QE5@74030|Roseovarius 28211|Alphaproteobacteria C COG2099 Precorrin-6x reductase cobK - 1.3.1.106,1.3.1.54 ko:K05895 ko00860,ko01100,map00860,map01100 - R05150,R05812 RC01280 ko00000,ko00001,ko01000 - - - CbiJ k141_14355_1 506534.Rhein_0937 5.08e-50 167.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1S1Z5@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 k141_14355_2 640511.BC1002_4073 6.59e-16 77.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2VIUC@28216|Betaproteobacteria,1K7Z8@119060|Burkholderiaceae 28216|Betaproteobacteria S 2-Nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO k141_9463_1 1288826.MSNKSG1_14037 1.12e-06 50.1 COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,1RNSM@1236|Gammaproteobacteria,466Y1@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily pagO - - - - - - - - - - - EamA k141_9463_2 472759.Nhal_3473 1.44e-53 176.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1WW5C@135613|Chromatiales 135613|Chromatiales V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA k141_18586_1 1278309.KB907099_gene2704 1.02e-115 340.0 COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,1RRPT@1236|Gammaproteobacteria,1XH5A@135619|Oceanospirillales 135619|Oceanospirillales E Alcohol dehydrogenase GroES-like domain fdhA - 1.2.1.46 ko:K00148 ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200 - R00604 RC00188 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k141_18586_2 399739.Pmen_4544 1.5e-43 149.0 COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria 1236|Gammaproteobacteria L dna polymerase iii - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k141_11625_1 236097.ADG881_869 1.54e-68 216.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XHRF@135619|Oceanospirillales 135619|Oceanospirillales S ABC transporter, ATP-binding protein - - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k141_1880_1 1122599.AUGR01000001_gene103 2.62e-21 90.5 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1XR9S@135619|Oceanospirillales 135619|Oceanospirillales EH Branched-chain amino acid aminotransferase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k141_1880_2 1278309.KB907106_gene1263 5.72e-315 870.0 COG3851@1|root,COG3851@2|Bacteria,1QUAD@1224|Proteobacteria,1RMGY@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase uhpB GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 M00473,M00818 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,MASE1 k141_1880_3 1278309.KB907106_gene1262 9.41e-96 282.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1XJIV@135619|Oceanospirillales 135619|Oceanospirillales E COG2755 Lysophospholipase L1 and related esterases tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 k141_1880_4 1278309.KB907106_gene1261 4.09e-130 374.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1XJAU@135619|Oceanospirillales 135619|Oceanospirillales Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_1880_5 1278309.KB907106_gene1260 9.51e-39 144.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XHVX@135619|Oceanospirillales 135619|Oceanospirillales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_13066_1 1288826.MSNKSG1_08223 5.23e-52 175.0 2EIBS@1|root,33C35@2|Bacteria,1QVXE@1224|Proteobacteria,1SHEY@1236|Gammaproteobacteria,468VS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flagellar hook-length control protein FliK - - - - - - - - - - - - Flg_hook k141_13066_2 1288826.MSNKSG1_08228 9.11e-69 208.0 COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,1SCWV@1236|Gammaproteobacteria,468FB@72275|Alteromonadaceae 1236|Gammaproteobacteria N homolog of the cytoplasmic domain of flagellar protein FhlB flhB2 - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 k141_13066_3 1288826.MSNKSG1_08233 6.82e-252 692.0 COG0714@1|root,COG0714@2|Bacteria,1QDUZ@1224|Proteobacteria,1RQGT@1236|Gammaproteobacteria,469BG@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases yehL - - - - - - - - - - - AAA_5 k141_13066_4 1288826.MSNKSG1_08238 7.49e-113 344.0 COG2518@1|root,COG2804@1|root,COG2518@2|Bacteria,COG2804@2|Bacteria,1R5CG@1224|Proteobacteria,1RV00@1236|Gammaproteobacteria,469V8@72275|Alteromonadaceae 1236|Gammaproteobacteria NOU Type II secretion system (T2SS), protein E, N-terminal domain - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - PCMT,T2SSE,T2SSE_N k141_15846_1 670487.Ocepr_1561 4.54e-09 57.0 2DQNP@1|root,337TM@2|Bacteria,1WJYU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - k141_15846_2 675814.VIC_004297 9.01e-09 57.4 2AWG7@1|root,31NCG@2|Bacteria,1QK3G@1224|Proteobacteria,1TI69@1236|Gammaproteobacteria,1XYGT@135623|Vibrionales 135623|Vibrionales S Domain of unknown function (DUF4345) - - - - - - - - - - - - DUF4345 k141_13758_1 1288826.MSNKSG1_04181 2e-84 256.0 COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,467YG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0036094,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k141_13758_2 1288826.MSNKSG1_04176 1.74e-128 365.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,467CU@72275|Alteromonadaceae 1236|Gammaproteobacteria S adenosyltransferase pduO - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans,Haem_degrading k141_13758_3 1288826.MSNKSG1_04171 0.0 1034.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQE2@1236|Gammaproteobacteria,4676E@72275|Alteromonadaceae 1236|Gammaproteobacteria NT COG0840 Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal k141_13758_4 1288826.MSNKSG1_04166 3.28e-199 553.0 COG3725@1|root,COG3725@2|Bacteria,1RH1N@1224|Proteobacteria,1S6GK@1236|Gammaproteobacteria,467BI@72275|Alteromonadaceae 1236|Gammaproteobacteria V Membrane protein required for beta-lactamase induction ampE - - ko:K03807 - - - - ko00000 - - - AmpE k141_13758_5 1288826.MSNKSG1_04161 1.99e-125 358.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,46701@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG3023 Negative regulator of beta-lactamase expression ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Amidase_2 k141_13758_6 1288826.MSNKSG1_04156 5.71e-168 491.0 COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,1T261@1236|Gammaproteobacteria,465VJ@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Protein of unknown function (DUF1631) - - - - - - - - - - - - DUF1631 k141_9475_1 580332.Slit_1617 1.55e-98 304.0 COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the NiFe NiFeSe hydrogenase large subunit family - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases k141_16513_1 335283.Neut_0937 1.4e-87 276.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,372VA@32003|Nitrosomonadales 28216|Betaproteobacteria O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k141_7478_1 1123368.AUIS01000011_gene1180 3.71e-94 299.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 k141_508_1 1469245.JFBG01000051_gene2132 2.92e-87 273.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_508_2 472759.Nhal_3896 1.54e-17 82.4 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_12389_1 1123360.thalar_01645 1.71e-81 254.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2TRP9@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0569 K transport systems, NAD-binding component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N k141_5398_1 765912.Thimo_0697 3.44e-70 222.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1WXDA@135613|Chromatiales 135613|Chromatiales S A predicted alpha-helical domain with a conserved ER motif. - - - - - - - - - - - - Alpha-E k141_2561_1 1122599.AUGR01000023_gene4165 9.23e-63 202.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1XHJM@135619|Oceanospirillales 135619|Oceanospirillales C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k141_2561_2 1278309.KB907110_gene3189 2.35e-221 615.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,1XHMK@135619|Oceanospirillales 135619|Oceanospirillales C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k141_2561_3 1278309.KB907110_gene3190 2.49e-54 185.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1XHUX@135619|Oceanospirillales 135619|Oceanospirillales T PrkA family serine protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k141_4711_1 525903.Taci_0157 2.9e-20 96.7 COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,3TAMT@508458|Synergistetes 508458|Synergistetes T histidine kinase A domain protein - - - - - - - - - - - - GGDEF,HATPase_c,HisKA,Hpt,Response_reg k141_22090_1 1122599.AUGR01000008_gene2555 1.12e-31 122.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XH8Y@135619|Oceanospirillales 135619|Oceanospirillales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos k141_21435_2 754476.Q7A_2837 1.23e-42 141.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales 72273|Thiotrichales H Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k141_21435_3 243233.MCA0098 1.68e-161 466.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XDYT@135618|Methylococcales 135618|Methylococcales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_19976_1 580332.Slit_2034 6.23e-09 56.2 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,44UZT@713636|Nitrosomonadales 28216|Betaproteobacteria P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip k141_19976_2 472759.Nhal_2317 2.9e-66 211.0 COG0204@1|root,COG0204@2|Bacteria,1PDUQ@1224|Proteobacteria,1S51R@1236|Gammaproteobacteria,1X1S0@135613|Chromatiales 135613|Chromatiales I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k141_12390_1 1122194.AUHU01000003_gene2298 2.07e-36 141.0 COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,464BZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria icmF - - ko:K11891 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - IcmF-related,IcmF_C,ImcF-related_N k141_3943_1 367336.OM2255_09451 4.47e-95 288.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k141_2562_2 518766.Rmar_0621 2.83e-17 75.1 COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1FJNC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k141_5399_1 1237149.C900_04531 5.69e-68 223.0 COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47JUX@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated protein GldE gldE - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_1897_1 1278309.KB907099_gene3010 1.51e-99 296.0 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,1XIRC@135619|Oceanospirillales 135619|Oceanospirillales E Allophanate hydrolase - - - - - - - - - - - - CT_A_B k141_1897_2 1278309.KB907099_gene3011 9.43e-147 416.0 COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,1XHH1@135619|Oceanospirillales 135619|Oceanospirillales E Allophanate hydrolase - - - - - - - - - - - - CT_C_D k141_1897_3 1278309.KB907099_gene3012 6.97e-157 442.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,1XIKT@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k141_1897_4 1278309.KB907099_gene3013 8.42e-190 526.0 COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,1RN4P@1236|Gammaproteobacteria,1XHXY@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the D-glutamate cyclase family - - - - - - - - - - - - DUF1445 k141_1897_6 1278309.KB907099_gene3015 1.06e-17 83.2 COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XIPG@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing EAL and modified HD-GYP domains - - - - - - - - - - - - EAL,HDOD k141_19342_1 580332.Slit_2429 4.19e-31 116.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2VU5M@28216|Betaproteobacteria 28216|Betaproteobacteria S Tellurite resistance protein TerB - - - - - - - - - - - - TerB k141_17954_1 44689.DDB0252883 6.21e-46 167.0 KOG3825@1|root,KOG3825@2759|Eukaryota,3XBKG@554915|Amoebozoa 554915|Amoebozoa L Deoxyribonuclease II - - 3.1.22.1 ko:K01158 ko04142,map04142 - - - ko00000,ko00001,ko01000 - - - DNase_II k141_21436_1 1269813.ATUL01000008_gene1511 9.04e-26 103.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k141_12391_1 1123517.JOMR01000001_gene1037 7.1e-17 84.7 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1SBFD@1236|Gammaproteobacteria,461AX@72273|Thiotrichales 72273|Thiotrichales S Protein conserved in bacteria - - - - - - - - - - - - - k141_19977_1 323261.Noc_3022 8.94e-78 247.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales 135613|Chromatiales EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k141_7479_1 1278309.KB907102_gene18 6.43e-209 592.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k141_1222_2 1278309.KB907103_gene1188 0.0 1637.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1XHDB@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.117 ko:K20455 ko00640,map00640 - R11263 RC01152 ko00000,ko00001,ko01000 - - - Aconitase,Aconitase_C k141_1222_3 1278309.KB907103_gene1187 6.47e-265 726.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,1XI36@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt k141_1222_4 1278309.KB907103_gene1186 1.61e-55 180.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,1XI1U@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase k141_3944_1 999550.KI421507_gene3450 4.89e-66 206.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE k141_510_1 1278309.KB907105_gene1525 4.62e-156 447.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XHR4@135619|Oceanospirillales 135619|Oceanospirillales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 k141_13760_1 626887.J057_02305 2.4e-61 209.0 COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,469CV@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction histidine kinase regulating citrate malate metabolism dcuS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 2.7.13.3 ko:K02476,ko:K07701,ko:K11614 ko02020,map02020 M00488,M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 k141_6027_2 1268068.PG5_55490 5.64e-36 125.0 COG2010@1|root,COG2010@2|Bacteria,1N7JC@1224|Proteobacteria 1224|Proteobacteria C COG2010 Cytochrome c, mono- and diheme variants - - - ko:K20200 ko00623,ko01120,map00623,map01120 - R02675,R11194 RC00769 ko00000,ko00001 - - - Cytochrome_CBB3 k141_8800_1 396588.Tgr7_3143 1.41e-80 267.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,CHASE4,EAL,GGDEF k141_4870_2 1121019.AUMN01000010_gene2154 5.04e-21 95.5 COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,1W880@1268|Micrococcaceae 201174|Actinobacteria C FMN-dependent dehydrogenase - - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh k141_20045_1 396588.Tgr7_1294 1.34e-38 138.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1WY4W@135613|Chromatiales 135613|Chromatiales S PFAM Uncharacterised protein family (UPF0227) - - - ko:K07000 - - - - ko00000 - - - UPF0227 k141_20045_2 228410.NE0621 9.72e-42 139.0 COG1359@1|root,COG1359@2|Bacteria,1PVN1@1224|Proteobacteria,2W4K2@28216|Betaproteobacteria,373DC@32003|Nitrosomonadales 28216|Betaproteobacteria C Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM k141_20045_3 261292.Nit79A3_1583 1.95e-127 374.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2W9B6@28216|Betaproteobacteria,372NE@32003|Nitrosomonadales 28216|Betaproteobacteria C alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH k141_7608_1 1449350.OCH239_16650 2.04e-110 333.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,4KMA7@93682|Roseivivax 28211|Alphaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k141_3478_1 998674.ATTE01000001_gene3480 3.03e-89 275.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4602X@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k141_3478_2 1196323.ALKF01000182_gene5242 1.73e-05 47.4 COG2267@1|root,COG2267@2|Bacteria,1V1Y6@1239|Firmicutes,4HFW7@91061|Bacilli,26SM4@186822|Paenibacillaceae 91061|Bacilli I Alpha beta hydrolase pcaD - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k141_15199_2 1278309.KB907103_gene1089 1.34e-79 238.0 COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein uspA - - ko:K06149 - - - - ko00000 - - - Usp k141_15199_3 1278309.KB907103_gene1090 4.9e-88 261.0 2AXNW@1|root,31PPD@2|Bacteria,1RJSX@1224|Proteobacteria,1S6SP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15199_4 283942.IL1584 1.68e-25 96.3 COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,2QGKC@267893|Idiomarinaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1653) - - - - - - - - - - - - DUF1653 k141_15199_5 1278309.KB907103_gene1092 4.31e-125 361.0 29T2C@1|root,30E8V@2|Bacteria,1RG9N@1224|Proteobacteria,1S3YX@1236|Gammaproteobacteria,1XJJ1@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15199_6 1278309.KB907103_gene1093 0.0 1590.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XIHW@135619|Oceanospirillales 135619|Oceanospirillales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom k141_15199_7 1278309.KB907103_gene1094 1.75e-109 316.0 2C7JX@1|root,322VC@2|Bacteria,1N2M6@1224|Proteobacteria,1S68U@1236|Gammaproteobacteria,1XKAU@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15199_8 1278309.KB907103_gene1095 4.79e-34 120.0 2EHUF@1|root,33BK2@2|Bacteria,1NMAC@1224|Proteobacteria,1SGY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_15199_9 1278309.KB907103_gene1096 3.51e-82 245.0 COG5404@1|root,COG5404@2|Bacteria,1RD22@1224|Proteobacteria,1RYWE@1236|Gammaproteobacteria,1XKI1@135619|Oceanospirillales 135619|Oceanospirillales D Cell division inhibitor SulA - - - - - - - - - - - - SulA k141_15199_10 1278309.KB907103_gene1097 1.89e-126 361.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1XJ8P@135619|Oceanospirillales 135619|Oceanospirillales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_15199_11 1278309.KB907103_gene1098 0.0 1295.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XIVR@135619|Oceanospirillales 135619|Oceanospirillales KL helicase dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII k141_15199_12 1278309.KB907103_gene1099 7.16e-269 744.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XH7F@135619|Oceanospirillales 135619|Oceanospirillales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C k141_15199_13 1278309.KB907103_gene1100 2.79e-256 713.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XH4M@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0061 (SELO) family - - - - - - - - - - - - UPF0061 k141_15199_14 1278309.KB907103_gene1101 4.88e-32 113.0 2ESX3@1|root,33KFF@2|Bacteria,1NH3W@1224|Proteobacteria,1SIN0@1236|Gammaproteobacteria,1XMPS@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_15199_15 1278309.KB907103_gene1102 1.77e-24 100.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XI3C@135619|Oceanospirillales 135619|Oceanospirillales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k141_20819_1 1269813.ATUL01000005_gene1975 4.82e-66 212.0 COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,1RNKV@1236|Gammaproteobacteria,1WW87@135613|Chromatiales 135613|Chromatiales S Bacterial lipid A biosynthesis acyltransferase - - - - - - - - - - - - Lip_A_acyltrans k141_21589_2 1165096.ARWF01000001_gene1888 1.97e-14 68.9 2EJUZ@1|root,333IS@2|Bacteria,1NFIG@1224|Proteobacteria,2VWAA@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k141_21589_3 697282.Mettu_0466 4.6e-16 77.4 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1XE62@135618|Methylococcales 135618|Methylococcales E PFAM Aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 k141_6203_1 1122599.AUGR01000024_gene1377 1.38e-08 59.7 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XISX@135619|Oceanospirillales 135619|Oceanospirillales NU Tfp pilus assembly protein, tip-associated adhesin PilY1 - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k141_10443_1 1288826.MSNKSG1_18250 2.24e-169 486.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,464F2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k141_10443_2 1288826.MSNKSG1_18255 0.0 1356.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,464GR@72275|Alteromonadaceae 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k141_10443_3 1288826.MSNKSG1_18260 1.22e-50 159.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,468J3@72275|Alteromonadaceae 1236|Gammaproteobacteria J Binds the 23S rRNA rpmE GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 k141_10443_4 1288826.MSNKSG1_18265 8.75e-121 354.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,465MY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0281 Malic enzyme maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic k141_4016_2 426114.THI_0245 3.37e-39 141.0 COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,2WGQY@28216|Betaproteobacteria,1KN64@119065|unclassified Burkholderiales 28216|Betaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_16022_1 349521.HCH_02504 3.21e-83 258.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 1.1.1.219,4.2.1.46 ko:K00091,ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k141_7609_1 946483.Cenrod_1884 5.19e-48 168.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,4ABK0@80864|Comamonadaceae 28216|Betaproteobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_16661_1 1278309.KB907101_gene582 5.03e-84 249.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,1XKRT@135619|Oceanospirillales 135619|Oceanospirillales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA k141_16661_2 1278309.KB907101_gene581 9.68e-95 278.0 29C1Y@1|root,2ZZ0F@2|Bacteria,1REVX@1224|Proteobacteria,1S4BA@1236|Gammaproteobacteria,1XMFU@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3087) - - - - - - - - - - - - DUF3087 k141_8971_1 243277.VC_0125 1.38e-43 153.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XSWN@135623|Vibrionales 135623|Vibrionales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k141_8971_2 396588.Tgr7_0042 2.53e-52 172.0 COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1WWQ9@135613|Chromatiales 135613|Chromatiales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 k141_10444_1 322710.Avin_44200 1.64e-13 75.1 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Secretion Protein VVA0148 - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k141_3479_1 1085623.GNIT_1757 0.000498 47.4 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,466SQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 k141_3479_2 1249627.D779_2185 3.29e-49 166.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1WWGF@135613|Chromatiales 135613|Chromatiales F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k141_7610_1 1469613.JT55_07230 2.3e-25 100.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2TSP3@28211|Alphaproteobacteria,3FDAJ@34008|Rhodovulum 28211|Alphaproteobacteria M LrgB-like family lrgB - - - - - - - - - - - LrgB k141_7610_2 1288298.rosmuc_02101 2.45e-70 216.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2TT92@28211|Alphaproteobacteria,46Q2N@74030|Roseovarius 28211|Alphaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids cobO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR k141_18784_1 1249627.D779_0551 2.52e-23 95.1 COG2153@1|root,COG2153@2|Bacteria,1N7TN@1224|Proteobacteria,1SCI6@1236|Gammaproteobacteria,1WYQK@135613|Chromatiales 135613|Chromatiales S protein acetylation - - - - - - - - - - - - - k141_18784_3 1005048.CFU_3902 1.39e-41 152.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,472DD@75682|Oxalobacteraceae 28216|Betaproteobacteria S protease with the C-terminal PDZ - - - - - - - - - - - - PDZ_2,Peptidase_M61 k141_10445_1 634500.EbC_12110 2.07e-67 217.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,3X5NS@551|Erwinia 1236|Gammaproteobacteria M Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 ko:K07806 ko00520,ko01503,ko02020,map00520,map01503,map02020 M00721,M00761 R07659 RC00006,RC01514 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 - - iSFxv_1172.SFxv_2574 DegT_DnrJ_EryC1 k141_17356_1 1288826.MSNKSG1_08143 0.0 1103.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,464UW@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2902 NAD-specific glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k141_17356_2 1288826.MSNKSG1_08138 3.43e-162 454.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,466D6@72275|Alteromonadaceae 1236|Gammaproteobacteria P Reversible hydration of carbon dioxide can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Pro_CA k141_20820_1 1278309.KB907100_gene2220 4.27e-116 337.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,1XR7H@135619|Oceanospirillales 135619|Oceanospirillales V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_20820_2 1121033.AUCF01000014_gene1270 1.63e-22 95.5 COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2TX2S@28211|Alphaproteobacteria,2JZ2A@204441|Rhodospirillales 204441|Rhodospirillales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_8972_1 1122137.AQXF01000001_gene2834 4.9e-08 58.9 COG0500@1|root,COG2226@2|Bacteria,1RHJG@1224|Proteobacteria,2U9N0@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Methyltransf_31 k141_21590_1 1279009.ADICEAN_02919 9.46e-153 463.0 COG1038@1|root,COG1038@2|Bacteria,4NFHU@976|Bacteroidetes,47N5S@768503|Cytophagia 976|Bacteroidetes C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second cfiB - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA k141_6204_1 1278309.KB907103_gene1056 9.7e-213 595.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XH3K@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer k141_16662_1 1278309.KB907099_gene2604 4.93e-243 676.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1XJKY@135619|Oceanospirillales 135619|Oceanospirillales J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase k141_16024_1 713586.KB900536_gene82 1.01e-26 106.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS k141_16024_2 545276.KB898724_gene2063 2.96e-106 323.0 COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1X2EG@135613|Chromatiales 135613|Chromatiales P PUA-like domain - - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 k141_647_1 207954.MED92_02636 9.58e-90 275.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XHQ6@135619|Oceanospirillales 135619|Oceanospirillales E Required for the activity of the bacterial periplasmic transport system of putrescine - - - ko:K11069,ko:K11073 ko02010,map02010 M00299,M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1,3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 k141_647_2 207954.MED92_02641 7.03e-278 765.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHHJ@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutamine synthetase family - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C k141_647_3 207954.MED92_02646 7.38e-223 623.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XIRJ@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO k141_2725_1 754477.Q7C_1650 6.62e-95 289.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,4606R@72273|Thiotrichales 72273|Thiotrichales L ATPase (AAA - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N k141_2725_2 1049564.TevJSym_ah00210 1.15e-37 129.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1J6UX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB k141_2013_1 713586.KB900536_gene2264 7.38e-32 120.0 COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,DUF302 k141_2013_2 713586.KB900536_gene2263 1.18e-33 122.0 COG3439@1|root,COG3439@2|Bacteria,1N3NF@1224|Proteobacteria,1ST0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - k141_2013_3 697282.Mettu_3269 1.44e-34 139.0 COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XDJQ@135618|Methylococcales 135618|Methylococcales F PFAM Adenylate cyclase, class-I - - 4.6.1.1 ko:K05851 ko00230,ko02026,ko05111,map00230,map02026,map05111 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - Adenyl_cycl_N,Adenylate_cycl k141_5558_1 1232683.ADIMK_0290 5.96e-276 760.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RYGT@1236|Gammaproteobacteria,466BG@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit benA - 1.14.12.10 ko:K05549 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k141_5558_2 1395571.TMS3_0115520 4.53e-79 238.0 COG5517@1|root,COG5517@2|Bacteria,1RAVG@1224|Proteobacteria,1S4XB@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG5517 Small subunit of phenylpropionate dioxygenase benB - 1.14.12.10 ko:K05550 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_01871 Ring_hydroxyl_B k141_5558_3 1042209.HK44_005470 1.28e-135 394.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RN9X@1236|Gammaproteobacteria,1YRI0@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Oxidoreductase FAD-binding domain benC GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.25,1.18.1.7 ko:K05784,ko:K14581,ko:K16161 ko00362,ko00364,ko00622,ko00624,ko00626,ko00627,ko00633,ko00642,ko00680,ko01100,ko01120,ko01200,ko01220,map00362,map00364,map00622,map00624,map00626,map00627,map00633,map00642,map00680,map01100,map01120,map01200,map01220 M00174,M00534,M00551,M00638 R01142,R02968,R05290,R05291,R05422,R05423,R05424,R05425,R05426,R05427,R05428,R05621,R05622,R05665,R06909,R06930,R06937,R07704,R07706,R07709,R07710,R08100,R08101,R08108,R08109,R08110,R09159,R09233 RC00091,RC00098,RC00157,RC00173,RC00270,RC00274,RC00275,RC00490,RC01376,RC01377,RC01378,RC01450,RC01801,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k141_6205_1 563040.Saut_0792 9.82e-07 55.5 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH k141_20821_1 317025.Tcr_0436 4.61e-122 355.0 COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,1S5NE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like k141_4017_1 1049564.TevJSym_bp00150 1.1e-159 454.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1J4QF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.6,2.1.3.9 ko:K00611,ko:K09065,ko:K13252 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k141_4017_2 717772.THIAE_06015 6.41e-14 69.7 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG0790 FOG TPR repeat, SEL1 subfamily Z012_10315 - - ko:K07126 - - - - ko00000 - - - Sel1 k141_4874_1 301.JNHE01000002_gene2283 8.33e-41 154.0 COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1YEBJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 - - R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 - - - DAO,Methyltransf_30 k141_21591_1 991.IW20_11560 1.61e-17 85.5 COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia,2NT2N@237|Flavobacterium 976|Bacteroidetes P TonB-dependent receptor phuR - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec k141_10447_1 225937.HP15_2341 1.65e-83 263.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,465KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0729 Outer membrane protein ytfM GO:0002790,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 k141_7613_1 523791.Kkor_0017 1.46e-49 177.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XHTD@135619|Oceanospirillales 135619|Oceanospirillales L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep - 3.6.4.12 ko:K03656 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k141_648_1 398580.Dshi_0154 1.97e-19 83.6 COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VG85@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NAD(P)H-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red k141_648_2 1366046.HIMB11_02952 2.53e-17 76.6 2BYIU@1|root,30YX8@2|Bacteria,1PKTI@1224|Proteobacteria,2UZFC@28211|Alphaproteobacteria,3ZHY9@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k141_9665_1 1288826.MSNKSG1_12932 0.0 889.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,464KJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair rapA GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - Helicase_C,RapA_C,SNF2_N k141_9665_2 1288826.MSNKSG1_12937 5.43e-175 488.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,4671M@72275|Alteromonadaceae 1236|Gammaproteobacteria E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - ko:K06203 - - - - ko00000 - - iJR904.b2413,iYL1228.KPN_02760 EI24 k141_9665_3 1288826.MSNKSG1_12942 3.76e-87 256.0 COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,1SGEP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM VanZ - - - - - - - - - - - - VanZ k141_9665_4 1288826.MSNKSG1_12952 1.33e-121 350.0 COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,1S3YF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S methyltransferase - - - - - - - - - - - - PrmA k141_16699_1 243233.MCA2977 4.37e-56 194.0 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,1XDPA@135618|Methylococcales 135618|Methylococcales T Histidine kinase - - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c k141_6241_1 1260251.SPISAL_01960 8.91e-10 60.1 COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,1S5RT@1236|Gammaproteobacteria,1X0MN@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1614) - - - - - - - - - - - - DUF1614 k141_6241_2 565045.NOR51B_537 4.36e-83 258.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1JACS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the ribose-phosphate pyrophosphokinase family - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N k141_19488_1 572480.Arnit_2548 2.19e-47 162.0 COG0500@1|root,COG0500@2|Bacteria,1QZYW@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - - k141_2751_1 1278309.KB907107_gene1703 3.33e-156 451.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XI62@135619|Oceanospirillales 135619|Oceanospirillales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_2751_2 1278309.KB907107_gene1702 2.19e-99 294.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNWB@1236|Gammaproteobacteria,1XJ9S@135619|Oceanospirillales 135619|Oceanospirillales U PFAM MotA TolQ ExbB proton channel - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB k141_14551_1 391615.ABSJ01000034_gene1021 1.44e-15 73.2 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J chain release factor yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k141_14551_2 29486.NJ56_12855 2.13e-97 296.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,41F54@629|Yersinia 1236|Gammaproteobacteria S alpha/beta hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k141_20343_2 1111732.AZOD01000028_gene779 1.27e-38 135.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1SYQJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Sugar transferase - - - ko:K13012 - - - - ko00000,ko01005 - - - Bac_transf k141_1480_1 1168067.JAGP01000001_gene409 3.35e-55 189.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF k141_9840_1 472759.Nhal_2379 5.88e-142 440.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales 135613|Chromatiales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_4266_1 666681.M301_0510 2.09e-19 85.5 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KN77@206350|Nitrosomonadales 206350|Nitrosomonadales T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl k141_4266_2 1121935.AQXX01000141_gene2070 2.13e-23 94.7 2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,1XMGS@135619|Oceanospirillales 135619|Oceanospirillales S PilZ domain - - - - - - - - - - - - PilZ k141_10557_1 1123058.KB894240_gene1966 9.26e-78 238.0 COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,1HWQ3@117743|Flavobacteriia 976|Bacteroidetes M Transferase wcgN - 2.7.8.36 ko:K15915 - - R10184 RC00002 ko00000,ko01000 - - - Bac_transf k141_795_1 1117958.PE143B_0126040 3.34e-54 182.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB1 - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_18921_1 279714.FuraDRAFT_2631 1.98e-57 196.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,2KPPS@206351|Neisseriales 206351|Neisseriales G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI k141_18921_2 1123368.AUIS01000009_gene2489 1.09e-24 103.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,2NC1J@225057|Acidithiobacillales 225057|Acidithiobacillales H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k141_7062_1 391619.PGA1_c32800 2.27e-111 343.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,34E44@302485|Phaeobacter 28211|Alphaproteobacteria C Aldehyde dehydrogenase family aldA - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_4267_1 261292.Nit79A3_2959 8.5e-75 242.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,372QB@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k141_12648_1 1278309.KB907099_gene2505 5.43e-84 256.0 COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,1RR15@1236|Gammaproteobacteria,1XJI6@135619|Oceanospirillales 135619|Oceanospirillales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 k141_12648_2 1278309.KB907099_gene2504 8.47e-167 476.0 COG0715@1|root,COG0715@2|Bacteria,1MWUA@1224|Proteobacteria,1S2B3@1236|Gammaproteobacteria,1XK1M@135619|Oceanospirillales 135619|Oceanospirillales P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - NMT1 k141_8458_1 1499967.BAYZ01000009_gene5347 4.1e-70 226.0 COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria 2|Bacteria S Vacuole effluxer Atg22 like yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 k141_19600_2 187272.Mlg_0825 6.19e-121 347.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1WW5U@135613|Chromatiales 135613|Chromatiales F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD,dUTPase k141_796_1 1218074.BAXZ01000010_gene2464 1.52e-11 63.9 COG1999@1|root,COG1999@2|Bacteria,1RKIP@1224|Proteobacteria,2VS9B@28216|Betaproteobacteria,1K2MK@119060|Burkholderiaceae 28216|Betaproteobacteria S Electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_796_2 1043493.BBLU01000011_gene271 4.41e-17 80.9 COG2847@1|root,COG2847@2|Bacteria,2IR3D@201174|Actinobacteria 201174|Actinobacteria S protein conserved in bacteria - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_4268_1 1163409.UUA_07245 5.11e-59 196.0 COG0454@1|root,COG1947@1|root,COG0454@2|Bacteria,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1X30B@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,GHMP_kinases_C,GHMP_kinases_N k141_14750_1 1278309.KB907100_gene2069 1.13e-82 260.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria,1XIYZ@135619|Oceanospirillales 135619|Oceanospirillales G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N k141_14750_2 1278309.KB907100_gene2068 1e-84 251.0 COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,1S92X@1236|Gammaproteobacteria,1XK77@135619|Oceanospirillales 135619|Oceanospirillales I dehydratase - - 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydratas k141_14750_3 1278309.KB907100_gene2067 7.29e-110 318.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1XJPK@135619|Oceanospirillales 135619|Oceanospirillales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k141_14750_4 1278309.KB907100_gene2066 5.13e-110 332.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1XHI6@135619|Oceanospirillales 135619|Oceanospirillales IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k141_11284_1 1168065.DOK_06125 2.7e-79 254.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k141_15470_1 1288826.MSNKSG1_10613 1.8e-160 452.0 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,466PK@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD k141_19625_2 1278309.KB907101_gene738 1.33e-134 386.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1XHER@135619|Oceanospirillales 135619|Oceanospirillales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase k141_16129_1 391165.GbCGDNIH1_1270 9.97e-35 137.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,2JR77@204441|Rhodospirillales 204441|Rhodospirillales P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran k141_10575_1 644107.SL1157_A0170 1.23e-132 387.0 COG0395@1|root,COG0395@2|Bacteria,1MUMG@1224|Proteobacteria,2TVBP@28211|Alphaproteobacteria,4NB65@97050|Ruegeria 28211|Alphaproteobacteria P Binding-protein-dependent transport systems inner membrane component aglG - - ko:K10234 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - BPD_transp_1 k141_12661_1 1196031.ALEG01000047_gene212 3.52e-34 123.0 COG1622@1|root,COG1622@2|Bacteria,1V4J8@1239|Firmicutes,4HHHE@91061|Bacilli,1ZCSP@1386|Bacillus 91061|Bacilli C oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 k141_12661_2 472759.Nhal_0418 5.38e-08 55.1 COG0843@1|root,COG0843@2|Bacteria,1QDZV@1224|Proteobacteria,1RYXY@1236|Gammaproteobacteria,1X0EJ@135613|Chromatiales 135613|Chromatiales C PFAM cytochrome c oxidase subunit I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k141_21688_1 1288826.MSNKSG1_16966 1.34e-73 223.0 COG1580@1|root,COG1580@2|Bacteria,1ND67@1224|Proteobacteria,1SDZM@1236|Gammaproteobacteria,468F7@72275|Alteromonadaceae 1236|Gammaproteobacteria N Controls the rotational direction of flagella during chemotaxis - - - ko:K02415 - - - - ko00000,ko02035 - - - FliL k141_21688_2 351348.Maqu_0468 2.13e-98 288.0 COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,467E0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein dsbB - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB k141_21688_3 1288826.MSNKSG1_16976 5.42e-108 311.0 COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,4678R@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the Rsd AlgQ family rsd GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ k141_7803_1 367336.OM2255_09586 1.74e-27 106.0 COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase gst - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N_3 k141_7803_2 571166.KI421509_gene3903 9.9e-52 170.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly k141_18239_1 519989.ECTPHS_07486 3.67e-75 241.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1WYMY@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase k141_18239_2 76114.ebA1169 1.86e-51 175.0 COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,2VPZX@28216|Betaproteobacteria,2KVZZ@206389|Rhodocyclales 206389|Rhodocyclales K LytTr DNA-binding domain - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k141_18239_3 998674.ATTE01000001_gene2628 2.95e-10 60.8 COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,1T4CA@1236|Gammaproteobacteria,463WF@72273|Thiotrichales 72273|Thiotrichales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 k141_7079_2 1278309.KB907100_gene2225 6.26e-116 334.0 COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,1XJDA@135619|Oceanospirillales 135619|Oceanospirillales F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran k141_7079_3 1278309.KB907100_gene2224 2.71e-314 867.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1XHT6@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_5719_1 1288826.MSNKSG1_01243 2.19e-53 172.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,4650X@72275|Alteromonadaceae 1236|Gammaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k141_5719_2 1288826.MSNKSG1_01248 6.88e-192 533.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,466AI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD k141_5719_3 1288826.MSNKSG1_01253 1.94e-196 547.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,466QJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S aminomethyltransferase related to GcvT ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C k141_5719_5 1288826.MSNKSG1_01263 1.67e-58 181.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,468IZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Flavinator of succinate dehydrogenase ygfY GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 k141_5719_6 1288826.MSNKSG1_01268 0.0 1093.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,464BS@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k141_5719_7 1288826.MSNKSG1_01273 5.02e-134 382.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_11980_1 1123392.AQWL01000008_gene1214 4.03e-20 88.6 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,1KTFM@119069|Hydrogenophilales 119069|Hydrogenophilales G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k141_14773_1 1278309.KB907099_gene2649 4.84e-57 190.0 COG0644@1|root,COG0644@2|Bacteria,1R3YA@1224|Proteobacteria,1RSKZ@1236|Gammaproteobacteria,1XHXF@135619|Oceanospirillales 135619|Oceanospirillales C Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k141_14773_2 1278309.KB907099_gene2648 1.01e-135 389.0 COG1404@1|root,COG1404@2|Bacteria,1MYNH@1224|Proteobacteria,1S5IH@1236|Gammaproteobacteria,1XK1U@135619|Oceanospirillales 135619|Oceanospirillales O Subtilase family - - - - - - - - - - - - Peptidase_S8 k141_14773_3 207954.MED92_14003 2.65e-15 75.9 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1S0VQ@1236|Gammaproteobacteria,1XI1P@135619|Oceanospirillales 135619|Oceanospirillales V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran k141_84_1 998674.ATTE01000001_gene2477 1.02e-42 149.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1S3NG@1236|Gammaproteobacteria,460PS@72273|Thiotrichales 72273|Thiotrichales S PFAM Copper chaperone SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_84_2 1249627.D779_0981 3.62e-40 139.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1WYZ4@135613|Chromatiales 135613|Chromatiales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC k141_2899_1 396588.Tgr7_0125 3.06e-94 306.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4CC@1236|Gammaproteobacteria,1X2QS@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Response_reg k141_2899_2 1177179.A11A3_14712 5.09e-54 181.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RNIM@1236|Gammaproteobacteria,1XQZY@135619|Oceanospirillales 135619|Oceanospirillales EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Osmo_CC,Sugar_tr k141_14065_2 1528098.NOVO_08120 1.17e-24 96.7 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,47FFJ@766|Rickettsiales 766|Rickettsiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 k141_18949_1 1123401.JHYQ01000038_gene1595 5.63e-24 99.4 2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18949_3 2340.JV46_05640 5.31e-26 97.1 2C7TU@1|root,32RJT@2|Bacteria,1N2CD@1224|Proteobacteria,1S96C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_18949_4 1249627.D779_3302 2.02e-09 58.9 COG0547@1|root,COG0547@2|Bacteria,1QDR6@1224|Proteobacteria,1T9UH@1236|Gammaproteobacteria,1WW56@135613|Chromatiales 135613|Chromatiales E PFAM Glycosyl transferase, family - - - - - - - - - - - - Glycos_trans_3N,Glycos_transf_3 k141_19626_2 748658.KB907325_gene664 9.23e-17 79.3 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales 135613|Chromatiales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_17517_1 1288826.MSNKSG1_12462 2.61e-66 213.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N k141_17517_2 1288826.MSNKSG1_12457 1.69e-233 643.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,464RG@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0056 PdxA k141_17517_3 1288826.MSNKSG1_12452 1.56e-191 532.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,464VH@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k141_17517_4 1288826.MSNKSG1_12447 1.1e-197 547.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,4658I@72275|Alteromonadaceae 1236|Gammaproteobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074 Metallophos k141_17517_5 1288826.MSNKSG1_12442 2.12e-80 240.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,468G6@72275|Alteromonadaceae 1236|Gammaproteobacteria S small membrane protein ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 k141_17517_6 1288826.MSNKSG1_12437 8.59e-39 129.0 COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,46922@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG2104 Sulfur transfer protein involved in thiamine biosynthesis thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS k141_17517_7 1288826.MSNKSG1_12432 4.15e-189 525.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,465GP@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 ThiG k141_17517_8 1288826.MSNKSG1_12427 1.36e-130 371.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,465HE@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions slmA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N k141_18240_1 1207063.P24_18784 5.31e-45 149.0 COG2963@1|root,COG2963@2|Bacteria,1NH66@1224|Proteobacteria,2UD9V@28211|Alphaproteobacteria,2JUTK@204441|Rhodospirillales 204441|Rhodospirillales L Evidence 4 Homologs of previously reported genes of - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k141_11981_1 1279009.ADICEAN_02917 2.07e-16 76.3 2CJFR@1|root,32RQT@2|Bacteria,4NVPU@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k141_11981_2 1047013.AQSP01000029_gene2170 3.02e-39 145.0 COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase k141_7081_1 1168067.JAGP01000001_gene162 6.35e-31 119.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,4612J@72273|Thiotrichales 72273|Thiotrichales M Lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k141_10578_1 436308.Nmar_1245 6.36e-73 239.0 COG0419@1|root,COG1122@1|root,arCOG00202@2157|Archaea,arCOG00368@2157|Archaea,41S9P@651137|Thaumarchaeota 651137|Thaumarchaeota LP AAA domain - - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_15 k141_19627_1 1342302.JASC01000014_gene2166 1.47e-85 282.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3ZY2S@60136|Sulfitobacter 28211|Alphaproteobacteria T Sterile alpha motif. - - - - - - - - - - - - AAA_16,BTAD,DZR,Guanylate_cyc,SAM_1,SAM_2,TPR_12 k141_4970_1 519989.ECTPHS_08261 5.02e-98 298.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase k141_18241_1 396588.Tgr7_0129 1.26e-34 127.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1WWVF@135613|Chromatiales 135613|Chromatiales S Competence protein - - - - - - - - - - - - Pribosyltran k141_2198_1 1168065.DOK_07389 9.41e-13 67.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1J4PE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K02533,ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_2198_2 998674.ATTE01000001_gene1025 1.51e-88 268.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,46025@72273|Thiotrichales 72273|Thiotrichales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k141_7082_1 83406.HDN1F_01790 3.25e-103 325.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1J55N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NT Chemotaxis protein histidine kinase cheA3 - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k141_3606_1 519989.ECTPHS_03719 4.13e-100 311.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_5720_1 95619.PM1_0227220 2.09e-152 440.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k141_12119_1 1286106.MPL1_00737 3.96e-43 142.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,4631K@72273|Thiotrichales 72273|Thiotrichales O selT selW selH selenoprotein - - - ko:K07401 - - - - ko00000 - - - Rdx k141_12119_2 283942.IL1622 5.3e-33 122.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,2QGDV@267893|Idiomarinaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB k141_7949_1 1278309.KB907099_gene2722 1.6e-208 580.0 COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,1RS4Y@1236|Gammaproteobacteria,1XJ3G@135619|Oceanospirillales 135619|Oceanospirillales P PBP superfamily domain - - - - - - - - - - - - HTH_1,PBP_like k141_7949_2 1278309.KB907099_gene2721 1.33e-06 48.9 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1XJMK@135619|Oceanospirillales 135619|Oceanospirillales C Thioredoxin-like [2Fe-2S] ferredoxin - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - 2Fe-2S_thioredx k141_5106_1 1007105.PT7_1087 5.37e-73 232.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,3T2BH@506|Alcaligenaceae 28216|Betaproteobacteria P Chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp k141_21208_1 1288826.MSNKSG1_06333 2.3e-53 186.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4643G@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine synthase metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k141_21208_2 1288826.MSNKSG1_06328 5.76e-136 385.0 COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,465AK@72275|Alteromonadaceae 1236|Gammaproteobacteria C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins nfuA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - ko:K07400 - - - - ko00000 - - - Fe-S_biosyn,NifU k141_21208_3 1288826.MSNKSG1_06323 2.7e-284 776.0 COG4399@1|root,COG4399@2|Bacteria,1R42C@1224|Proteobacteria,1RPWG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF445 k141_21208_4 1288826.MSNKSG1_06318 4.16e-74 221.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,467QI@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of a sulfur-relay system tusE GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC k141_21208_5 1288826.MSNKSG1_06313 1.1e-54 171.0 COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions tusB GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH k141_21208_6 1288826.MSNKSG1_06308 1.35e-76 228.0 COG2923@1|root,COG2923@2|Bacteria 2|Bacteria P tRNA processing tusC GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07236 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DrsE k141_21208_7 1288826.MSNKSG1_06303 7.11e-93 271.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,467M1@72275|Alteromonadaceae 1236|Gammaproteobacteria P conserved protein involved in intracellular sulfur reduction tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k141_21208_8 1288826.MSNKSG1_06298 8.9e-152 428.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,46771@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the BI1 family yccA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k141_21208_10 1288826.MSNKSG1_06288 4.89e-88 267.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,4643H@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase k141_21868_1 1510531.JQJJ01000009_gene1031 1.94e-41 151.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3JTTQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Sigma-54 interaction domain - - - ko:K02481,ko:K07714,ko:K11384 ko02020,map02020 M00500,M00505 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_21868_2 66429.JOFL01000006_gene2054 3.38e-26 105.0 COG2813@1|root,COG2813@2|Bacteria,2I8VY@201174|Actinobacteria 201174|Actinobacteria J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k141_19099_1 1288826.MSNKSG1_09778 2.39e-108 313.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,467Z8@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09941 - - - - ko00000 - - - DUF1415 k141_5107_1 1237149.C900_01121 5.92e-60 204.0 COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes,47MMG@768503|Cytophagia 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA,PD40 k141_6480_1 1122169.AREN01000022_gene11 2.17e-15 79.3 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K response regulator pilR - - - - - - - - - - - GerE,Response_reg k141_17688_1 1278309.KB907106_gene1259 1.2e-44 165.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,1XKKF@135619|Oceanospirillales 135619|Oceanospirillales M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA k141_1657_1 1208323.B30_14941 5.72e-68 225.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2TQKZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria N flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA k141_3050_1 1423144.Gal_00233 3.46e-19 83.2 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,34FII@302485|Phaeobacter 28211|Alphaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - HPPK k141_3050_2 644107.SL1157_1882 2.22e-62 192.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,4NC58@97050|Ruegeria 28211|Alphaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_3050_3 89187.ISM_13785 1.44e-16 79.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,46P1A@74030|Roseovarius 28211|Alphaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_7210_1 754476.Q7A_2172 2.57e-63 200.0 COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,1S3KC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - MarR_2,NTP_transf_2 k141_7210_2 1380387.JADM01000007_gene686 7.36e-11 59.7 2AXM7@1|root,31PMG@2|Bacteria,1RIYV@1224|Proteobacteria,1S732@1236|Gammaproteobacteria,1XKE9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_20508_1 1158165.KB898872_gene1094 5.48e-88 282.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.1,1.7.1.15 ko:K00362,ko:K05297 ko00071,ko00910,ko01120,map00071,map00910,map01120 M00530 R00787,R02000 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 k141_8612_1 338963.Pcar_3048 3.79e-103 302.0 2A70U@1|root,30VW1@2|Bacteria,1RGBZ@1224|Proteobacteria,42VYK@68525|delta/epsilon subdivisions,2WSFU@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 k141_8612_2 207954.MED92_14313 8.76e-40 134.0 COG5470@1|root,COG5470@2|Bacteria,1NBM7@1224|Proteobacteria,1SFKK@1236|Gammaproteobacteria,1XMHX@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 k141_8612_3 314345.SPV1_01822 1.09e-144 410.0 COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria 1224|Proteobacteria O Methyl-transferase - - - - - - - - - - - - ICMT,PEMT k141_8612_4 224911.27354821 3.18e-50 166.0 2B1WH@1|root,30C4Q@2|Bacteria,1R3E9@1224|Proteobacteria,2U7UN@28211|Alphaproteobacteria,3K27G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG k141_16980_1 390235.PputW619_0632 1.87e-31 114.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1YY59@136845|Pseudomonas putida group 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 k141_16980_2 1236959.BAMT01000004_gene824 4.26e-25 102.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,2KM7R@206350|Nitrosomonadales 206350|Nitrosomonadales P PFAM CBS domain - - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC k141_19750_1 1089552.KI911559_gene2017 6.18e-37 126.0 COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2JT7W@204441|Rhodospirillales 204441|Rhodospirillales L Transposase - - - - - - - - - - - - HTH_Tnp_1 k141_11422_1 7668.SPU_005613-tr 4.46e-08 60.5 KOG0613@1|root,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria 33208|Metazoa T myosin light chain kinase activity - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - I-set,Pkinase,fn3 k141_11422_2 1123400.KB904754_gene1013 6.38e-87 268.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,460H3@72273|Thiotrichales 72273|Thiotrichales S PFAM YicC-like family, N-terminal region - - - - - - - - - - - - DUF1732,YicC_N k141_11422_3 626887.J057_04751 2.99e-76 235.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,466I4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k141_11422_4 1335757.SPICUR_01535 1.43e-25 100.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales 135613|Chromatiales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k141_11422_5 765914.ThisiDRAFT_1993 8.06e-148 439.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k141_14901_1 990285.RGCCGE502_07961 7.21e-32 127.0 COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,4BAYB@82115|Rhizobiaceae 28211|Alphaproteobacteria T Response regulator containing a CheY-like receiver domain and a GGDEF domain pleD GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF,Response_reg k141_14901_2 543913.D521_1162 6.6e-75 239.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WGST@28216|Betaproteobacteria,1KR82@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase rubB - 1.18.1.1 ko:K05297,ko:K12265 ko00071,ko05132,map00071,map05132 - R02000 - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_13492_1 1288826.MSNKSG1_17561 2.93e-183 512.0 2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 k141_13492_2 1288826.MSNKSG1_17566 6.76e-128 365.0 COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,46CF3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_13492_3 1288826.MSNKSG1_17571 1.75e-135 386.0 COG5662@1|root,COG5662@2|Bacteria,1NGBV@1224|Proteobacteria,1SGXN@1236|Gammaproteobacteria,46BR4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 k141_13492_4 1288826.MSNKSG1_17576 5.19e-59 186.0 2AYIH@1|root,31QN9@2|Bacteria,1QN8E@1224|Proteobacteria,1SH36@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13492_5 1288826.MSNKSG1_17581 6.84e-281 772.0 COG0457@1|root,COG0457@2|Bacteria,1N8R8@1224|Proteobacteria,1SBTP@1236|Gammaproteobacteria,468VH@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16 k141_13492_6 1288826.MSNKSG1_17586 2.98e-250 690.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,463YV@72275|Alteromonadaceae 1236|Gammaproteobacteria H Glutamate-1-semialdehyde aminotransferase hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 k141_7951_2 765910.MARPU_06210 9.68e-70 220.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales 135613|Chromatiales O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k141_232_1 1121935.AQXX01000142_gene2229 1.05e-21 95.5 COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XK35@135619|Oceanospirillales 135619|Oceanospirillales NT CheW-like domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_232_2 1515746.HR45_13830 1.16e-71 219.0 COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,2QAKC@267890|Shewanellaceae 1236|Gammaproteobacteria NT PFAM CheW domain protein cheW - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k141_935_1 1278309.KB907100_gene2097 1.23e-109 319.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XJD4@135619|Oceanospirillales 135619|Oceanospirillales P COG1392 Phosphate transport regulator (distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div k141_935_2 553385.JEMF01000039_gene2928 2.27e-38 139.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XIG9@135619|Oceanospirillales 135619|Oceanospirillales P phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 k141_9955_1 521011.Mpal_0355 1.72e-53 181.0 arCOG08055@1|root,arCOG08055@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - Methyltransf_11 k141_18380_1 1288826.MSNKSG1_09043 1.29e-223 623.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,4641S@72275|Alteromonadaceae 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k141_18380_2 1288826.MSNKSG1_09048 1.27e-62 194.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,467RH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 k141_4462_1 1288826.MSNKSG1_05396 2.65e-249 686.0 COG0420@1|root,COG0420@2|Bacteria,1MY4X@1224|Proteobacteria,1RSFB@1236|Gammaproteobacteria,468KQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0420 DNA repair exonuclease - - - - - - - - - - - - Metallophos k141_4462_2 1288826.MSNKSG1_05401 6e-161 478.0 COG1196@1|root,COG1196@2|Bacteria,1QU97@1224|Proteobacteria,1T3AS@1236|Gammaproteobacteria,467TR@72275|Alteromonadaceae 1236|Gammaproteobacteria D COG0419 ATPase involved in DNA repair - - - - - - - - - - - - AAA_23,AAA_27 k141_21870_1 1244869.H261_21708 2.04e-16 87.0 COG4251@1|root,COG4251@2|Bacteria,1R2YE@1224|Proteobacteria 1224|Proteobacteria T signal transduction Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_9 k141_1658_1 765913.ThidrDRAFT_3532 1.93e-73 244.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales 135613|Chromatiales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA k141_5108_1 1278309.KB907104_gene840 2.81e-46 164.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,1XRAP@135619|Oceanospirillales 135619|Oceanospirillales S Cobalamin synthesis protein cobW C-terminal domain - - - - - - - - - - - - cobW k141_5108_2 2340.JV46_08500 1.64e-41 142.0 2DTFC@1|root,33K4P@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - 2OG-FeII_Oxy_5 k141_19751_1 472759.Nhal_3799 4.44e-59 189.0 COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales 135613|Chromatiales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k141_9270_1 443152.MDG893_07760 0.0 1010.0 COG1061@1|root,COG2227@1|root,COG2932@1|root,COG3886@1|root,COG1061@2|Bacteria,COG2227@2|Bacteria,COG2932@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4657B@72275|Alteromonadaceae 1236|Gammaproteobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,Methyltransf_25,PLDc_2,ResIII k141_3052_1 572477.Alvin_1573 9.97e-58 197.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WWDP@135613|Chromatiales 135613|Chromatiales NT histidine kinase HAMP region domain protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k141_11423_2 323848.Nmul_A1364 9.3e-41 142.0 COG0741@1|root,COG0741@2|Bacteria,1Q0FH@1224|Proteobacteria,2W58U@28216|Betaproteobacteria 28216|Betaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k141_1659_1 765912.Thimo_1749 2.2e-69 222.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - k141_5844_3 301.JNHE01000068_gene2663 4.03e-09 53.9 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ k141_5844_4 375286.mma_1634 1.57e-79 248.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae 28216|Betaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N k141_10748_1 391616.OA238_c41960 1.07e-08 55.5 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems senC - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC k141_10748_2 367336.OM2255_09131 3.83e-50 163.0 COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain regA GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K15012 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg k141_19772_1 870187.Thini_3765 8.61e-21 92.4 COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD k141_9976_1 631362.Thi970DRAFT_04809 1.43e-35 143.0 COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXS9@135613|Chromatiales 1236|Gammaproteobacteria NT PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain - - - ko:K03406,ko:K05875 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CHASE3,HAMP,MCPsignal,TarH,dCache_1 k141_19123_1 1122197.ATWI01000011_gene443 1.57e-88 284.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 k141_16262_1 2340.JV46_02580 7.85e-19 85.1 COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,1S76Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 k141_3075_1 391593.RCCS2_17966 2.41e-158 460.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,2P1JF@2433|Roseobacter 28211|Alphaproteobacteria T membrane GTPase involved in stress response typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k141_5128_1 754476.Q7A_982 1.1e-24 104.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales 72273|Thiotrichales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_5128_2 338963.Pcar_0271 1.23e-108 330.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,43UX8@69541|Desulfuromonadales 28221|Deltaproteobacteria I PLD-like domain - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 k141_2327_2 1121378.KB899704_gene2461 4.46e-05 47.0 COG2217@1|root,COG2217@2|Bacteria,1WJ55@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P ATPase P-type (Transporting), HAD superfamily, subfamily IC pacS - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase k141_2327_3 1283300.ATXB01000001_gene33 8.32e-57 189.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XFW1@135618|Methylococcales 135618|Methylococcales P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex k141_9291_2 202952.BBLI01000032_gene2295 4.06e-05 49.3 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,3NIWA@468|Moraxellaceae 1236|Gammaproteobacteria K Sigma-54 interaction domain - - - ko:K11914,ko:K12266 ko05132,map05132 - - - ko00000,ko00001,ko02044,ko03000 - - - HTH_8,Sigma54_activat,V4R,XylR_N k141_961_1 261292.Nit79A3_0750 6.62e-75 231.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,2WGF2@28216|Betaproteobacteria,371P0@32003|Nitrosomonadales 28216|Betaproteobacteria L NUDIX domain - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k141_961_2 1049564.TevJSym_ag00570 2.84e-36 132.0 COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6- deoxy-6-sulfo-D-fructose 1-phosphate (SFP) yihV GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0061594,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 2.7.1.184,2.7.1.3 ko:K00846,ko:K18478 ko00051,ko01100,ko01120,map00051,map01100,map01120 - R00866,R03819,R10970 RC00002,RC00017,RC00608 ko00000,ko00001,ko01000,ko04147 - - - PfkB,Rieske k141_255_2 911239.CF149_21083 1.41e-108 327.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P found to be peripherally associated with the inner membrane in Escherichia coli trkA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iE2348C_1286.E2348C_3552 TrkA_C,TrkA_N k141_17090_1 1323663.AROI01000002_gene1221 1.22e-56 182.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k141_17090_2 247634.GPB2148_605 7.13e-108 323.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1J4KE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein k141_18486_1 1304885.AUEY01000035_gene2235 4.23e-56 181.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42SPM@68525|delta/epsilon subdivisions,2WMYY@28221|Deltaproteobacteria,2MK4C@213118|Desulfobacterales 28221|Deltaproteobacteria S Haemolysin-III related - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k141_18486_2 1049564.TevJSym_ax00140 2.72e-41 143.0 COG3193@1|root,COG3193@2|Bacteria,1REZG@1224|Proteobacteria,1S5K5@1236|Gammaproteobacteria,1JB26@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading k141_18486_3 717785.HYPMC_0044 1.24e-12 70.9 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,3N71V@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria CO Thioredoxin-like tlpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - AhpC-TSA,Redoxin k141_13632_1 588068.H9YAF4_9CAUD 5.13e-22 101.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k141_2462_1 323261.Noc_0723 9.07e-12 65.1 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat k141_12959_2 2340.JV46_16140 9.18e-78 236.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1J5V2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k141_6611_1 1288826.MSNKSG1_09628 1.54e-218 604.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,465RV@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI,HTH_18 k141_6611_3 1288826.MSNKSG1_09638 8.36e-153 447.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_8123_1 1415778.JQMM01000001_gene1543 1.87e-14 74.7 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1J5PD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k141_5260_1 357808.RoseRS_4625 1.19e-19 90.5 COG0778@1|root,COG0778@2|Bacteria,2GAR2@200795|Chloroflexi,377W1@32061|Chloroflexia 32061|Chloroflexia C Nitroreductase family - - - - - - - - - - - - Nitroreductase k141_5260_2 243233.MCA2827 5.88e-21 89.0 COG2236@1|root,COG2236@2|Bacteria,1RKB0@1224|Proteobacteria,1S7J1@1236|Gammaproteobacteria,1XFMX@135618|Methylococcales 135618|Methylococcales F Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran k141_8729_2 323261.Noc_0364 1.67e-69 225.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1WVVC@135613|Chromatiales 135613|Chromatiales F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_3851_1 1278309.KB907111_gene3347 1.48e-217 603.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1XH7N@135619|Oceanospirillales 135619|Oceanospirillales S Transcription factor - - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 k141_3851_2 1278309.KB907111_gene3348 3.01e-155 439.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XH6W@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA - - 2.1.1.200 ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k141_3851_3 1042209.HK44_006920 2.07e-87 274.0 COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,1RP5I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B k141_3851_4 1278309.KB907111_gene3349 7.64e-158 447.0 COG0596@1|root,COG0596@2|Bacteria,1QXP7@1224|Proteobacteria,1T5IG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 k141_3851_5 1278309.KB907111_gene3350 1.97e-310 848.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1XHPF@135619|Oceanospirillales 135619|Oceanospirillales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 k141_1093_1 766499.C357_21112 5.83e-77 248.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067,ko:K06192 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k141_10143_1 1049564.TevJSym_aw00330 1.85e-46 163.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k141_19886_1 582744.Msip34_1871 3.24e-67 218.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,2KKGB@206350|Nitrosomonadales 206350|Nitrosomonadales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_9401_1 160492.XF_1504 6.85e-47 162.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1X4G5@135614|Xanthomonadales 135614|Xanthomonadales S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N k141_12275_1 999549.KI421513_gene3292 2.54e-77 234.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,27ZFP@191028|Leisingera 28211|Alphaproteobacteria L Single-strand binding protein family ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k141_12973_1 1165841.SULAR_02433 2.66e-142 410.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria P Co Zn Cd efflux system component czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer k141_12973_2 1158146.KB907125_gene2237 1.03e-13 72.8 COG1575@1|root,COG1575@2|Bacteria 2|Bacteria H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA k141_3855_1 1049564.TevJSym_ax00490 2.45e-168 512.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k141_3855_2 1232683.ADIMK_0726 1.68e-122 355.0 COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1SYPB@1236|Gammaproteobacteria,469B5@72275|Alteromonadaceae 1236|Gammaproteobacteria K FCD - - - ko:K11474 - - - - ko00000,ko03000 - - - FCD,GntR k141_3855_3 1232683.ADIMK_0725 1.44e-226 629.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RY6Q@1236|Gammaproteobacteria,469XK@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_3855_4 1122201.AUAZ01000009_gene2763 5.25e-130 373.0 COG4665@1|root,COG4665@2|Bacteria,1RE14@1224|Proteobacteria,1S582@1236|Gammaproteobacteria,46AGS@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_15017_2 1122134.KB893650_gene1371 9.74e-16 72.8 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4597_1 555778.Hneap_0171 1.84e-15 80.9 COG1416@1|root,COG5662@1|root,COG1416@2|Bacteria,COG5662@2|Bacteria,1MYMK@1224|Proteobacteria,1SD2F@1236|Gammaproteobacteria,1X1AM@135613|Chromatiales 135613|Chromatiales K AntiSigma factor - - - ko:K09004 - - - - ko00000 - - - - k141_4597_2 1163617.SCD_n01931 1.48e-45 155.0 COG1595@1|root,COG1595@2|Bacteria,1RKQH@1224|Proteobacteria,2VSYG@28216|Betaproteobacteria 28216|Betaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k141_9402_1 1238450.VIBNISOn1_560001 2.29e-12 67.4 COG2206@1|root,COG2206@2|Bacteria,1RA8P@1224|Proteobacteria,1RSQ4@1236|Gammaproteobacteria,1Y0CI@135623|Vibrionales 135623|Vibrionales T Histidine Phosphotransfer domain - - - - - - - - - - - - HD_5,Hpt k141_9402_2 572477.Alvin_0866 3.19e-67 207.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria,1WXZR@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k141_19261_2 472759.Nhal_3696 9.37e-59 186.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, E subunit - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k141_19887_1 1163408.UU9_13653 1.11e-89 270.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1X4NB@135614|Xanthomonadales 135614|Xanthomonadales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k141_3218_1 1121004.ATVC01000005_gene1381 2.51e-52 189.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE,EAL,GGDEF,MASE1,PAS,PAS_7 k141_10879_1 1198232.CYCME_2487 4.51e-108 324.0 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales 72273|Thiotrichales O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm k141_10879_2 717772.THIAE_10505 2.02e-28 116.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein Ccs1 ResB - - - ko:K07399 - - - - ko00000 - - - ResB k141_13645_1 1124780.ANNU01000006_gene2808 3.77e-36 138.0 COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia 976|Bacteroidetes NU PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 k141_13645_2 1279009.ADICEAN_02041 1.66e-12 65.9 COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,47MRM@768503|Cytophagia 976|Bacteroidetes S PFAM (2R)-phospho-3-sulfolactate synthase ComA - - 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 - - - ComA k141_14293_1 768671.ThimaDRAFT_1183 2.24e-75 240.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1WWKI@135613|Chromatiales 135613|Chromatiales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_7 k141_17835_1 1121904.ARBP01000004_gene979 4.85e-46 168.0 COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,POTRA k141_5274_1 1415756.JQMY01000001_gene939 8.55e-131 394.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2PCC4@252301|Oceanicola 28211|Alphaproteobacteria C Belongs to the aldehyde dehydrogenase family aldA - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_3856_1 1116375.VEJY3_17691 2.26e-100 307.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVGD@135623|Vibrionales 135623|Vibrionales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k141_15018_1 1288826.MSNKSG1_08918 2.42e-134 396.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,4645D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) aidA - - - - - - - - - - - DUF1302 k141_13646_1 1278309.KB907101_gene395 5.31e-89 272.0 28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1XHY9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_17101_2 1535422.ND16A_0509 9.55e-21 87.4 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,2Q6ZG@267889|Colwelliaceae 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_17101_3 227377.CBU_0001 3.62e-38 142.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1JCEX@118969|Legionellales 118969|Legionellales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_413_1 187272.Mlg_1485 4.09e-65 221.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k141_8135_1 1415778.JQMM01000001_gene207 1.55e-69 217.0 COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,1J5SB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip k141_8135_2 1278309.KB907099_gene3104 2.3e-81 241.0 COG3232@1|root,COG3232@2|Bacteria,1RB8A@1224|Proteobacteria,1S3SG@1236|Gammaproteobacteria,1XJWW@135619|Oceanospirillales 135619|Oceanospirillales E 5-carboxymethyl-2-hydroxymuconate isomerase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - CHMI k141_8135_3 1278309.KB907099_gene3103 2.64e-276 761.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XHE8@135619|Oceanospirillales 135619|Oceanospirillales C belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 ko:K00130,ko:K00151,ko:K10217 ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00555,M00569 R02565,R02566,R02762,R03889,R04418,R05353 RC00080,RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k141_21336_2 314278.NB231_10083 4.43e-35 127.0 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,1S4UH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C k141_21336_3 396588.Tgr7_3151 2.78e-62 194.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales 135613|Chromatiales K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - Peptidase_S24 k141_3219_1 1249627.D779_1733 1.98e-20 90.9 COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,1WXQY@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 k141_3219_2 1249627.D779_1734 4.89e-62 191.0 COG0347@1|root,COG0347@2|Bacteria,1RIY4@1224|Proteobacteria,1S67U@1236|Gammaproteobacteria,1WYIZ@135613|Chromatiales 135613|Chromatiales K Belongs to the P(II) protein family - - - - - - - - - - - - P-II k141_3219_3 572477.Alvin_1923 2.66e-14 70.5 COG1051@1|root,COG1051@2|Bacteria,1RC3I@1224|Proteobacteria,1S34Y@1236|Gammaproteobacteria,1WY35@135613|Chromatiales 135613|Chromatiales F NUDIX domain - - - - - - - - - - - - NUDIX k141_4599_1 1461694.ATO9_05480 1.3e-67 216.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,2PC8T@252301|Oceanicola 28211|Alphaproteobacteria NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k141_14294_1 187272.Mlg_1179 2.51e-79 252.0 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1RY9Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_19263_1 314292.VAS14_17221 1.62e-46 163.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XU6C@135623|Vibrionales 135623|Vibrionales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k141_9403_1 1121921.KB898706_gene3345 3.91e-22 91.3 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,2PNR1@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria J Ribonuclease P rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P k141_9403_2 1026882.MAMP_00432 1.23e-17 75.1 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,461IG@72273|Thiotrichales 72273|Thiotrichales J Ribosomal protein L34 rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 k141_9403_3 187272.Mlg_0001 8.44e-104 315.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales 135613|Chromatiales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k141_17837_1 1288826.MSNKSG1_05151 6.63e-70 232.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,465AY@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes sucA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_18504_1 95619.PM1_0226550 2.68e-44 151.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k141_18504_2 396588.Tgr7_2901 7.38e-73 248.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X29W@135613|Chromatiales 135613|Chromatiales NT chemotaxis - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k141_15019_1 396588.Tgr7_2285 1.1e-73 236.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k141_13647_1 1278309.KB907106_gene1233 3.26e-196 549.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria,1XIG0@135619|Oceanospirillales 135619|Oceanospirillales P Amino acid ABC transporter, permease aapM - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 k141_12976_1 1278309.KB907105_gene1466 7.71e-41 140.0 COG2995@1|root,COG2995@2|Bacteria,1N2QU@1224|Proteobacteria,1S9RM@1236|Gammaproteobacteria,1XREU@135619|Oceanospirillales 135619|Oceanospirillales S Paraquat-inducible protein A - - - - - - - - - - - - PqiA k141_12976_2 1278309.KB907105_gene1465 1.57e-119 345.0 COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XIA3@135619|Oceanospirillales 135619|Oceanospirillales S paraquat-inducible protein A - - - - - - - - - - - - PqiA k141_12976_3 1278309.KB907105_gene1464 1.44e-42 154.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XJ1N@135619|Oceanospirillales 135619|Oceanospirillales Q Paraquat-inducible protein B - - - - - - - - - - - - MlaD k141_1812_2 243233.MCA1969 2.19e-138 397.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XET4@135618|Methylococcales 135618|Methylococcales Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k141_8737_2 1278309.KB907103_gene1112 3.41e-195 542.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1XHS5@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth k141_8737_3 1278309.KB907103_gene1113 1.37e-227 632.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1XIT6@135619|Oceanospirillales 135619|Oceanospirillales EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k141_8737_4 1278309.KB907103_gene1114 2.18e-48 155.0 2DPGF@1|root,331YU@2|Bacteria,1N6ZX@1224|Proteobacteria,1SDQJ@1236|Gammaproteobacteria,1XMBB@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_8737_5 1278309.KB907103_gene1115 4.4e-99 289.0 COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,1S2XX@1236|Gammaproteobacteria,1XQZ8@135619|Oceanospirillales 135619|Oceanospirillales S PHB accumulation regulatory domain - - - - - - - - - - - - PHB_acc,PHB_acc_N k141_8737_6 207954.MED92_05273 4.18e-34 119.0 COG4321@1|root,COG4321@2|Bacteria,1MZP2@1224|Proteobacteria,1S865@1236|Gammaproteobacteria,1XK3D@135619|Oceanospirillales 135619|Oceanospirillales S Ribbon-helix-helix domain - - - - - - - - - - - - RHH_4 k141_3220_1 236097.ADG881_3113 2.32e-61 198.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,1S21F@1236|Gammaproteobacteria,1XJVG@135619|Oceanospirillales 135619|Oceanospirillales S TRAP transporter T-component - - - - - - - - - - - - TAtT k141_1114_1 1278309.KB907103_gene1088 0.0 1021.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XIPX@135619|Oceanospirillales 135619|Oceanospirillales S mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_18012_2 1121921.KB898709_gene368 8.3e-167 469.0 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,2PMH4@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria P Formate/nitrite transporter fnt - - ko:K06212,ko:K21993 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 - - Form_Nir_trans k141_18012_4 1210884.HG799472_gene14777 9.19e-22 90.1 2E6DG@1|root,33113@2|Bacteria 2|Bacteria - - VP2964 - - - - - - - - - - - DUF4145 k141_20721_1 713586.KB900536_gene2986 4.77e-27 110.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1WW6E@135613|Chromatiales 135613|Chromatiales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g k141_17248_1 1469613.JT55_18275 3.84e-137 398.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components nrtA - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 k141_14406_1 296591.Bpro_0234 4.9e-13 70.5 COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2VX3A@28216|Betaproteobacteria,4AJB3@80864|Comamonadaceae 28216|Betaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k141_15890_2 1249627.D779_2199 5.13e-150 430.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k141_15890_3 318167.Sfri_2291 9.95e-15 73.6 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,2QAEU@267890|Shewanellaceae 1236|Gammaproteobacteria P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k141_11023_1 314256.OG2516_12251 1.15e-89 286.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,2PC8U@252301|Oceanicola 28211|Alphaproteobacteria K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - RNB,S1 k141_10298_1 1049564.TevJSym_ab02040 4.97e-40 141.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,1J6J1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterised protein family UPF0066 yaeB GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - - - - - - - - - - UPF0066 k141_22144_1 367299.JOEE01000001_gene1610 1.65e-79 263.0 COG2905@1|root,COG2905@2|Bacteria,2I91C@201174|Actinobacteria,4FEXU@85021|Intrasporangiaceae 201174|Actinobacteria T Putative nucleotidyltransferase DUF294 - - - ko:K07182 - - - - ko00000 - - - CBS,DUF294,DUF294_C,cNMP_binding k141_6089_1 367336.OM2255_03640 8.79e-96 298.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC-type oligopeptide transport system periplasmic component nikA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 k141_6732_1 292415.Tbd_1993 3.33e-34 120.0 COG4831@1|root,COG4831@2|Bacteria,1N4ET@1224|Proteobacteria 1224|Proteobacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_6732_2 2340.JV46_26610 1.48e-50 162.0 COG4831@1|root,COG4831@2|Bacteria,1N55K@1224|Proteobacteria 1224|Proteobacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 k141_11024_1 391613.RTM1035_01245 1.37e-115 337.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TUIC@28211|Alphaproteobacteria,46Q49@74030|Roseovarius 28211|Alphaproteobacteria P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component cmpD - - ko:K02049,ko:K15578 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.17 - - ABC_tran k141_9526_1 1121904.ARBP01000024_gene6617 1.26e-11 66.6 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF k141_19998_1 744979.R2A130_3320 2.81e-241 705.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k141_6090_1 1122137.AQXF01000001_gene2620 6.42e-15 79.3 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 k141_2602_1 1278309.KB907102_gene80 5.81e-109 324.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XHA2@135619|Oceanospirillales 135619|Oceanospirillales U type II secretion system protein pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF k141_2602_2 1441629.PCH70_43330 9.72e-37 134.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1Z4UK@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02464,ko:K02654 ko03070,map03070 M00331 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15,3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k141_11676_1 1165841.SULAR_05008 2.14e-24 103.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1 k141_11025_1 519989.ECTPHS_00660 1.71e-49 178.0 COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,1T23G@1236|Gammaproteobacteria,1X2J6@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k141_20723_1 1207063.P24_04315 5.55e-91 276.0 COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria,2V9I3@28211|Alphaproteobacteria,2JUKN@204441|Rhodospirillales 204441|Rhodospirillales S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k141_9527_1 140110.NechaP30214 1.18e-10 60.8 2B36M@1|root,2S0EA@2759|Eukaryota,3A28P@33154|Opisthokonta,3P2ZF@4751|Fungi,3QUSW@4890|Ascomycota,213A1@147550|Sordariomycetes,3TDC4@5125|Hypocreales,1FR8H@110618|Nectriaceae 4751|Fungi S to pyridoxamine phosphate oxidase family protein - - - - - - - - - - - - Putative_PNPOx k141_6091_1 929703.KE386491_gene38 2.02e-43 147.0 28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia 976|Bacteroidetes S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - DUF1599 k141_21482_1 1278309.KB907100_gene2020 1.05e-89 282.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k141_21482_2 1123514.KB905902_gene308 1.19e-27 105.0 COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,1S8EV@1236|Gammaproteobacteria,461DB@72273|Thiotrichales 72273|Thiotrichales S membrane - - - - - - - - - - - - - k141_21482_3 1278309.KB907100_gene2018 3.29e-78 234.0 COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,1SYS0@1236|Gammaproteobacteria,1XS84@135619|Oceanospirillales 135619|Oceanospirillales S Acyl-ACP thioesterase - - - - - - - - - - - - 4HBT_2 k141_4759_1 1288826.MSNKSG1_07063 1.93e-167 473.0 2AK3X@1|root,3369U@2|Bacteria,1N7U0@1224|Proteobacteria,1SD30@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_4759_2 1288826.MSNKSG1_07068 5.96e-263 720.0 2CAGX@1|root,2Z7W4@2|Bacteria,1P64Q@1224|Proteobacteria,1RPYY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_13127_1 1123392.AQWL01000003_gene150 3.7e-100 315.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1KSM8@119069|Hydrogenophilales 119069|Hydrogenophilales O HypF finger - - - - - - - - - - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF k141_12446_1 1288826.MSNKSG1_06228 8.93e-104 305.0 COG0300@1|root,COG0300@2|Bacteria,1RFF2@1224|Proteobacteria,1S4ME@1236|Gammaproteobacteria,46CWM@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k141_12446_2 1288826.MSNKSG1_06223 3.7e-104 301.0 COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,467W4@72275|Alteromonadaceae 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 k141_12446_3 1288826.MSNKSG1_06218 8.64e-106 311.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,465C3@72275|Alteromonadaceae 1236|Gammaproteobacteria I desaturase desC - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k141_5443_1 1232683.ADIMK_1384 1.83e-146 425.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,467IV@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_5443_2 1288826.MSNKSG1_10228 3.55e-24 100.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RRYY@1236|Gammaproteobacteria,469F2@72275|Alteromonadaceae 1236|Gammaproteobacteria EGP Transmembrane secretion effector bcr - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr k141_1943_1 1278309.KB907103_gene1035 1.96e-148 425.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XIBJ@135619|Oceanospirillales 135619|Oceanospirillales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - - - - - - - - - - - PALP k141_1943_2 1278309.KB907103_gene1036 2.35e-48 155.0 2B33B@1|root,31VQY@2|Bacteria,1QTM4@1224|Proteobacteria,1RXQ3@1236|Gammaproteobacteria,1XMRP@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k141_1943_3 1278309.KB907103_gene1037 4.96e-147 424.0 COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1XHAR@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate pdxB - 1.1.1.290 ko:K03473 ko00750,ko01100,map00750,map01100 M00124 R04210 RC00084 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C,DUF3410 k141_6733_1 998674.ATTE01000001_gene2309 9.78e-27 103.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity ung - 3.2.2.27 ko:K03648,ko:K21929 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k141_6733_2 247634.GPB2148_3824 1.17e-12 64.3 COG3089@1|root,COG3089@2|Bacteria,1PCAQ@1224|Proteobacteria,1SGN9@1236|Gammaproteobacteria,1J79D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria IV02_22800 - - ko:K09898 - - - - ko00000 - - - UPF0270 k141_15891_1 1278309.KB907099_gene2531 2.64e-209 605.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales 135619|Oceanospirillales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k141_15891_2 1278309.KB907099_gene2532 1.04e-28 114.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,1XI9Q@135619|Oceanospirillales 135619|Oceanospirillales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k141_18014_1 1288826.MSNKSG1_11818 1.93e-279 768.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1S1HS@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - DUF1298,WES_acyltransf k141_11677_1 572477.Alvin_2182 4.9e-23 99.8 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1WWTV@135613|Chromatiales 135613|Chromatiales O TIGRFAM Cytochrome c-type biogenesis protein CcmI - - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_2 k141_8843_1 1288826.MSNKSG1_12037 2.18e-140 407.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1SMIE@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf k141_8843_2 1288826.MSNKSG1_12042 1.05e-226 624.0 COG2267@1|root,COG2267@2|Bacteria,1REM5@1224|Proteobacteria,1S52K@1236|Gammaproteobacteria 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - - k141_8843_3 1288826.MSNKSG1_12047 3.94e-168 471.0 2DN8V@1|root,32W5E@2|Bacteria,1N1PA@1224|Proteobacteria,1SBHH@1236|Gammaproteobacteria,46DFH@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_8843_4 1288826.MSNKSG1_12052 9.8e-62 189.0 2EGJT@1|root,33ABY@2|Bacteria,1NGI4@1224|Proteobacteria,1SH79@1236|Gammaproteobacteria,46CBD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - - - - - - - - - - PHA_gran_rgn k141_8843_5 1288826.MSNKSG1_12057 3.84e-184 512.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,464M8@72275|Alteromonadaceae 1236|Gammaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Ubie_methyltran k141_8843_6 1288826.MSNKSG1_12062 1.59e-135 385.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,4689F@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 k141_15145_1 1298593.TOL_2566 2.44e-42 148.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1XIYR@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k141_15145_2 314278.NB231_02743 5.35e-93 282.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1WVWB@135613|Chromatiales 135613|Chromatiales GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k141_11037_1 472759.Nhal_3430 1.51e-147 433.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1WX8Q@135613|Chromatiales 135613|Chromatiales M Cell wall hydrolase autolysin - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k141_12463_1 864051.BurJ1DRAFT_1736 2.98e-21 90.9 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,2W30E@28216|Betaproteobacteria,1KNKV@119065|unclassified Burkholderiales 28216|Betaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD k141_12463_2 396588.Tgr7_0536 3.95e-07 54.3 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k141_20734_1 28229.ND2E_0765 1.34e-54 184.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,2Q5PC@267889|Colwelliaceae 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k141_20734_2 272123.Anacy_5045 1.66e-26 105.0 COG0057@1|root,COG0057@2|Bacteria,1G0ZV@1117|Cyanobacteria,1HKGS@1161|Nostocales 1117|Cyanobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap3 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k141_14427_3 1163617.SCD_n00546 7.26e-32 115.0 2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k141_14427_4 1336233.JAEH01000008_gene2195 2.28e-19 84.7 COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,1RRAF@1236|Gammaproteobacteria,2QB7C@267890|Shewanellaceae 1236|Gammaproteobacteria S Lysine methyltransferase - - - - - - - - - - - - Methyltransf_16 k141_6756_1 713587.THITH_06085 8.19e-39 146.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k141_10314_1 1288826.MSNKSG1_15372 7.39e-189 548.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,464RK@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iECs_1301.ECs3167,iG2583_1286.G2583_2820,iZ_1308.Z3542 Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k141_18685_1 1439940.BAY1663_03529 8.67e-89 266.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the GST superfamily - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_N k141_21504_1 318161.Sden_2591 3e-73 228.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,2Q98H@267890|Shewanellaceae 1236|Gammaproteobacteria O PFAM Glutathione S-transferase maiA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016034,GO:0016054,GO:0016853,GO:0016859,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3 k141_21504_2 283699.D172_0083 5.38e-18 86.3 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RXYJ@1236|Gammaproteobacteria,2Q5DU@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k141_2617_1 298386.PBPRB0577 2.43e-30 127.0 2DBPZ@1|root,2ZABJ@2|Bacteria,1R7CU@1224|Proteobacteria,1SKX7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_17267_4 697282.Mettu_4199 4.95e-31 112.0 2ADWZ@1|root,339E7@2|Bacteria,1NFWS@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_9538_1 1410620.SHLA_8c000240 6.38e-116 356.0 COG1653@1|root,COG1653@2|Bacteria,1N1NW@1224|Proteobacteria,2U094@28211|Alphaproteobacteria,4BBCW@82115|Rhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 k141_1289_1 1122201.AUAZ01000027_gene2208 1.5e-18 84.3 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RPA8@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_11693_2 228410.NE0370 6.57e-10 59.7 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,372VF@32003|Nitrosomonadales 28216|Betaproteobacteria C PFAM FAD dependent oxidoreductase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C k141_1953_1 519989.ECTPHS_10069 3.29e-36 142.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXMA@135613|Chromatiales 135613|Chromatiales T Chemotaxis sensory transducer - - - ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3 k141_7525_2 1288826.MSNKSG1_12372 3.66e-251 689.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae 1236|Gammaproteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 k141_7525_3 1288826.MSNKSG1_12367 3.52e-149 421.0 COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,1S52N@1236|Gammaproteobacteria,466YG@72275|Alteromonadaceae 1236|Gammaproteobacteria E threonine efflux protein - - - - - - - - - - - - LysE k141_7525_4 1288826.MSNKSG1_12362 0.0 934.0 COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria,464TA@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpd_2 - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k141_7525_5 1288826.MSNKSG1_12357 1.01e-102 298.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1S3UH@1236|Gammaproteobacteria,46CR7@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin k141_7525_6 930169.B5T_01548 2.83e-103 313.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,1RZ26@1236|Gammaproteobacteria,1XJPW@135619|Oceanospirillales 135619|Oceanospirillales M COG3203 Outer membrane protein (porin) - - - - - - - - - - - - Porin_4 k141_7525_7 1288826.MSNKSG1_12342 2.42e-282 771.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 k141_7525_8 1288826.MSNKSG1_12337 0.0 886.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,465ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa2 - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS k141_7525_9 1288826.MSNKSG1_12332 3.22e-287 787.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,4668P@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM k141_7525_10 1288826.MSNKSG1_12327 3.28e-131 372.0 COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,1S44W@1236|Gammaproteobacteria,467BV@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k141_7525_11 1288826.MSNKSG1_12322 1.7e-260 713.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,46527@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_7525_12 1288826.MSNKSG1_12317 1.92e-100 291.0 28PDJ@1|root,2ZC5G@2|Bacteria,1RCPJ@1224|Proteobacteria,1S3C7@1236|Gammaproteobacteria,468R2@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_7525_13 1288826.MSNKSG1_12312 1.49e-259 711.0 COG3525@1|root,COG3525@2|Bacteria,1QR2G@1224|Proteobacteria,1RZNM@1236|Gammaproteobacteria,466IG@72275|Alteromonadaceae 1236|Gammaproteobacteria G beta-N-acetylglucosaminidase - - 3.2.1.35 ko:K01197 ko00531,ko01100,map00531,map01100 M00076,M00077 R07824,R07825,R10905 - ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 - - - Glyco_hydro_20b,NAGidase k141_7525_14 1288826.MSNKSG1_12307 1.87e-155 437.0 COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,466G0@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09797 - - - - ko00000 - - - SIMPL k141_7525_15 1288826.MSNKSG1_12302 2.03e-104 303.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation ymdB GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - - - - - - - - - - Macro k141_20089_5 1288826.MSNKSG1_08578 1.45e-107 311.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,467SJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein affecting phage T7 exclusion by the F plasmid fxsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - ko:K07113 - - - - ko00000 - - - FxsA k141_20089_6 1288826.MSNKSG1_08583 2.38e-49 163.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,465UP@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 k141_9695_1 765912.Thimo_2955 6.07e-49 162.0 COG2193@1|root,COG2193@2|Bacteria,1PE4V@1224|Proteobacteria,1SAG5@1236|Gammaproteobacteria,1WZ24@135613|Chromatiales 135613|Chromatiales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k141_9695_3 1249627.D779_1746 2.17e-59 184.0 COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,1S5Y6@1236|Gammaproteobacteria,1WYHX@135613|Chromatiales 135613|Chromatiales CQ carboxysome shell protein - - - - - - - - - - - - BMC k141_9695_4 314278.NB231_15178 2.98e-26 99.4 COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,1S9JX@1236|Gammaproteobacteria,1WZ5P@135613|Chromatiales 135613|Chromatiales CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL k141_17424_1 1278309.KB907104_gene834 2.36e-189 538.0 COG1360@1|root,COG3455@1|root,COG1360@2|Bacteria,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1T1GU@1236|Gammaproteobacteria,1XR5C@135619|Oceanospirillales 135619|Oceanospirillales N Type VI secretion system protein DotU - - - ko:K11892 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DotU,OmpA k141_17424_2 1278309.KB907104_gene833 6.09e-67 214.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,1XHSM@135619|Oceanospirillales 135619|Oceanospirillales S type VI secretion protein, VC_A0114 family - - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k141_20868_1 62928.azo0514 5.43e-27 108.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VKUY@28216|Betaproteobacteria,2KVVJ@206389|Rhodocyclales 206389|Rhodocyclales C Part of a membrane complex involved in electron transport - - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_4068_1 1121935.AQXX01000018_gene3767 1.88e-05 46.6 COG1204@1|root,COG1204@2|Bacteria,1MW4Z@1224|Proteobacteria,1RXXN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DEAD DEAH box helicase - - - - - - - - - - - - DEAD,Helicase_C k141_4068_2 28229.ND2E_0062 8.59e-93 279.0 2C2MI@1|root,2ZBMN@2|Bacteria,1RAX0@1224|Proteobacteria,1S35B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1837) - - - - - - - - - - - - DUF1837 k141_6846_2 545264.KB898746_gene877 5.01e-37 132.0 COG0526@1|root,COG0526@2|Bacteria,1NAUV@1224|Proteobacteria,1SF3P@1236|Gammaproteobacteria,1WYJM@135613|Chromatiales 135613|Chromatiales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA k141_9696_1 646529.Desaci_2897 1.16e-33 124.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,2612Y@186807|Peptococcaceae 186801|Clostridia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k141_20090_1 455436.DS989813_gene1015 7.85e-29 113.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,464AJ@72275|Alteromonadaceae 1236|Gammaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k141_4069_1 1278309.KB907101_gene390 3.25e-49 169.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1XH5Z@135619|Oceanospirillales 135619|Oceanospirillales E FAD dependent oxidoreductase - - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO k141_6848_1 156578.ATW7_08846 1.47e-116 343.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2340 AIRS,AIRS_C k141_14595_1 105559.Nwat_3050 7.36e-188 549.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1WXCY@135613|Chromatiales 135613|Chromatiales G phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k141_14595_2 2340.JV46_16840 7.19e-136 392.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1J5E4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 AA_kinase,NAT k141_9697_1 1366050.N234_11485 3.78e-98 309.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae 28216|Betaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k141_20870_3 1121035.AUCH01000003_gene1334 3.53e-69 220.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VRFJ@28216|Betaproteobacteria,2KW3Z@206389|Rhodocyclales 206389|Rhodocyclales HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran k141_20870_4 522306.CAP2UW1_3901 2.77e-14 72.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,1KQUV@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria U FecCD transport family btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD k141_20091_1 323261.Noc_1657 3.26e-74 231.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1WXA1@135613|Chromatiales 135613|Chromatiales L TIGRFAM hydrolase, TatD family - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k141_20091_2 95619.PM1_0225755 2.43e-37 127.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU pilus assembly protein, PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ k141_9056_2 1288826.MSNKSG1_06763 1.31e-114 327.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,46785@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0260 family ycgN - - ko:K09160 - - - - ko00000 - - - CxxCxxCC k141_9056_3 1288826.MSNKSG1_06768 1.95e-58 181.0 COG3100@1|root,COG3100@2|Bacteria 2|Bacteria S YcgL domain-containing protein ycgL - - ko:K09902 - - - - ko00000 - - - YcgL k141_9056_4 1288826.MSNKSG1_06773 9.57e-266 729.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,464UE@72275|Alteromonadaceae 1236|Gammaproteobacteria J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC k141_9056_5 1288826.MSNKSG1_06778 7.59e-144 405.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,466DN@72275|Alteromonadaceae 1236|Gammaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 k141_9056_6 1288826.MSNKSG1_06783 2.83e-58 181.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,4683K@72275|Alteromonadaceae 1236|Gammaproteobacteria S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd k141_9056_7 1288826.MSNKSG1_06788 5.8e-86 272.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,464IG@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 k141_20871_1 511062.GU3_15605 2.13e-58 188.0 COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,1RYIX@1236|Gammaproteobacteria,1Y6HG@135624|Aeromonadales 135624|Aeromonadales T Transcriptional regulatory protein, C terminal - - - ko:K07774 ko02020,map02020 M00457 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k141_14596_1 395493.BegalDRAFT_0242 8.13e-135 417.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales 72273|Thiotrichales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran k141_6850_1 1208323.B30_20843 2.23e-129 371.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k141_2075_1 1255043.TVNIR_2381 3.72e-118 361.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB k141_2075_2 396588.Tgr7_2629 1.39e-55 185.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k141_4071_1 1120956.JHZK01000003_gene341 5.95e-54 184.0 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2TU5N@28211|Alphaproteobacteria,1JPV2@119043|Rhodobiaceae 28211|Alphaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp k141_6851_1 768671.ThimaDRAFT_2993 1.93e-80 257.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1WW1S@135613|Chromatiales 135613|Chromatiales V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k141_20872_1 1288826.MSNKSG1_01698 9.67e-94 276.0 COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,467AT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1279 Lysine efflux permease argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - iPC815.YPO0918 LysE k141_20872_2 225937.HP15_868 1.8e-44 151.0 COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,1RNIC@1236|Gammaproteobacteria,467JU@72275|Alteromonadaceae 1236|Gammaproteobacteria K Transcriptional regulator argP GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032297,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090329,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000104,GO:2000112,GO:2000113,GO:2001141 - ko:K05596 - - - - ko00000,ko03000,ko03036 - - - HTH_1,LysR_substrate k141_14598_1 153948.NAL212_3117 1.88e-96 308.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,372PZ@32003|Nitrosomonadales 28216|Betaproteobacteria L RNA polymerase recycling family C-terminal - - - ko:K03580 - - - - ko00000,ko01000,ko03021 - - - DUF3883,Helicase_C,RapA_C,ResIII,SNF2_N k141_9058_1 1278309.KB907104_gene909 4.18e-54 184.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XIJ4@135619|Oceanospirillales 135619|Oceanospirillales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_9058_2 1278309.KB907104_gene908 2.13e-158 448.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,1XJGK@135619|Oceanospirillales 135619|Oceanospirillales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k141_4072_2 519989.ECTPHS_13203 3.08e-244 688.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales 135613|Chromatiales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k141_14599_1 519989.ECTPHS_06307 1.03e-184 529.0 COG3408@1|root,COG3408@2|Bacteria,1R3W7@1224|Proteobacteria,1RVZH@1236|Gammaproteobacteria,1X040@135613|Chromatiales 135613|Chromatiales G Alkaline and neutral invertase - - - - - - - - - - - - Glyco_hydro_100 k141_9059_1 314278.NB231_06036 3.23e-23 97.4 COG5488@1|root,COG5488@2|Bacteria,1N9B7@1224|Proteobacteria,1SF1J@1236|Gammaproteobacteria,1X1FG@135613|Chromatiales 135613|Chromatiales S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 k141_2078_1 497321.C664_16013 1.53e-53 179.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KV7X@206389|Rhodocyclales 206389|Rhodocyclales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k141_4073_1 713586.KB900536_gene1727 3.8e-48 164.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales 135613|Chromatiales HJ TIGRFAM alpha-L-glutamate ligase-like protein - - - - - - - - - - - - ATPgrasp_ST k141_20873_4 472759.Nhal_0005 1.35e-152 444.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1X061@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k141_6852_1 1278309.KB907102_gene191 3.2e-64 217.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1XKF3@135619|Oceanospirillales 135619|Oceanospirillales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - SH3_3,Sel1 k141_6852_2 1278309.KB907102_gene192 7.68e-90 272.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,1XI5J@135619|Oceanospirillales 135619|Oceanospirillales M Domain of unknown function (DUF3524) - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 k141_9060_1 883126.HMPREF9710_02552 1.41e-56 194.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,473HW@75682|Oxalobacteraceae 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k141_20093_1 1166016.W5S_1258 7.06e-155 459.0 COG0223@1|root,COG0451@1|root,COG0223@2|Bacteria,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1MR8T@122277|Pectobacterium 1236|Gammaproteobacteria I Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 ko:K01784,ko:K10011 ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503 M00361,M00362,M00632,M00721,M00761 R00291,R02984,R07658,R07660 RC00026,RC00289,RC01575,RC01812 ko00000,ko00001,ko00002,ko01000,ko01005 - - iPC815.YPO2420,iSFV_1184.SFV_2325 Epimerase,Formyl_trans_C,Formyl_trans_N k141_20093_2 1121396.KB893024_gene3900 2.1e-135 394.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria,2MN5W@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyltransferase like family 2 arnC - 2.4.2.53 ko:K10012,ko:K20534 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8,4.D.2.1.9 GT2 - Glycos_transf_2 k141_20093_3 1484158.PSNIH1_16690 2.54e-35 131.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,3VY7D@53335|Pantoea 1236|Gammaproteobacteria M Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides arnB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 ko:K07806 ko00520,ko01503,ko02020,map00520,map01503,map02020 M00721,M00761 R07659 RC00006,RC01514 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 - - iSFxv_1172.SFxv_2574 DegT_DnrJ_EryC1 k141_14600_1 1056820.KB900632_gene2207 1.15e-38 152.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,2PN6V@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Domain of unknown function (DUF4131) ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k141_14600_2 1517416.IDAT_02710 2.04e-63 199.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,2QFYA@267893|Idiomarinaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2062) TLL0138 - - ko:K09928 - - - - ko00000 - - - DUF2062 k141_9698_1 1288826.MSNKSG1_18575 8.95e-135 382.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,4686M@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019538,GO:0020037,GO:0030091,GO:0031224,GO:0031226,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - ko:K17247 - - - - ko00000 - - - Ferric_reduct k141_9698_2 1288826.MSNKSG1_18570 1.48e-202 561.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,464E2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb k141_9698_3 1288826.MSNKSG1_18565 8.98e-187 520.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4645F@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf k141_20874_1 439497.RR11_1140 5.25e-32 124.0 COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,2TR17@28211|Alphaproteobacteria,4NAAC@97050|Ruegeria 28211|Alphaproteobacteria V ABC transporter transmembrane region prsD - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran k141_20874_2 246200.SPO3727 1.27e-14 75.1 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria,4NB1P@97050|Ruegeria 28211|Alphaproteobacteria M VacJ family lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA k141_4074_1 1288826.MSNKSG1_04236 1.32e-126 387.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0474 Cation transport ATPase - - 3.6.3.6 ko:K01535,ko:K12955 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.24,3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase k141_15251_1 864069.MicloDRAFT_00039000 2.05e-155 442.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria,1JUEV@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 k141_15251_3 1278309.KB907099_gene2709 7.4e-216 598.0 COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1S03A@1236|Gammaproteobacteria,1XN5X@135619|Oceanospirillales 135619|Oceanospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k141_15251_4 1278309.KB907099_gene2710 2.03e-110 319.0 COG3090@1|root,COG3090@2|Bacteria,1RFS4@1224|Proteobacteria,1S4VU@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ k141_15251_5 1278309.KB907099_gene2711 7.36e-265 731.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RPU7@1236|Gammaproteobacteria,1XISS@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k141_15251_6 1278309.KB907099_gene2775 1.79e-112 324.0 COG1396@1|root,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,1S4B9@1236|Gammaproteobacteria,1XJVH@135619|Oceanospirillales 135619|Oceanospirillales K XRE family transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_3 k141_15251_7 1278309.KB907099_gene2776 1.81e-78 244.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1XHQT@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_6854_1 765914.ThisiDRAFT_2159 1.71e-75 241.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH k141_20875_1 637389.Acaty_c1032 6.28e-48 162.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_14602_2 109871.XP_006682955.1 2.05e-19 92.0 2D322@1|root,2SPY8@2759|Eukaryota,39XSF@33154|Opisthokonta,3PI67@4751|Fungi 33154|Opisthokonta S to Hypothetical protein CBG24020 - - - - - - - - - - - - - k141_2081_1 1328313.DS2_03830 7.54e-13 78.2 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,464CY@72275|Alteromonadaceae 1236|Gammaproteobacteria S membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 k141_20876_1 1278309.KB907099_gene2561 1.57e-110 337.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RZNZ@1236|Gammaproteobacteria,1XKDT@135619|Oceanospirillales 135619|Oceanospirillales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k141_6856_1 1168067.JAGP01000001_gene2073 1.64e-66 225.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales 72273|Thiotrichales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge k141_14603_2 1415778.JQMM01000001_gene571 4.57e-120 355.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1J4NN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA k141_15252_1 1206777.B195_19531 3.18e-89 290.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1Z4YA@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M Soluble lytic murein transglycosylase slt GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 iETEC_1333.ETEC_4747,iPC815.YPO0452 SLT,SLT_L k141_6857_1 1461693.ATO10_06406 1.08e-52 189.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria 28211|Alphaproteobacteria L double-strand break repair protein AddB addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 k141_11834_2 1278309.KB907101_gene674 1.68e-56 181.0 2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,1S4JB@1236|Gammaproteobacteria,1XJQ4@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2889) - - - - - - - - - - - - DUF2889 k141_4125_1 1283284.AZUK01000001_gene2523 7.26e-105 313.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1Y6GF@135624|Aeromonadales 135624|Aeromonadales P TOBE domain - - - ko:K10191 ko02010,map02010 M00199 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.4 - - ABC_tran,TOBE_2 k141_6936_1 1100720.ALKN01000028_gene2533 1.25e-13 70.5 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria,4A9NP@80864|Comamonadaceae 28216|Betaproteobacteria S FIST N domain - - - - - - - - - - - - FIST,FIST_C k141_6936_2 754476.Q7A_1472 6.5e-91 276.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales 72273|Thiotrichales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_6937_1 1121943.KB900000_gene1212 7.95e-68 221.0 28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3360) - - - - - - - - - - - - DUF3360 k141_20157_1 187272.Mlg_0341 3.82e-96 287.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1WWUW@135613|Chromatiales 135613|Chromatiales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k141_20157_2 391615.ABSJ01000042_gene2250 1.35e-19 87.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1J5GD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer k141_9737_1 1288826.MSNKSG1_08913 3.8e-213 594.0 28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1RN8H@1236|Gammaproteobacteria,464MQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1329) IV02_13580 - - - - - - - - - - - DUF1329 k141_9737_2 1288826.MSNKSG1_08908 5.41e-261 738.0 COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1S2DV@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE ## 24086 queries scanned ## Total time (seconds): 95.58936667442322 ## Rate: 251.97 q/s